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JOURNAL ARTICLE
Justine Hoch, Christina Hospodar, Gabriela Koch da Costa Aguiar Alves, Karen Adolph
Independent locomotion is associated with a range of positive developmental outcomes, but unlike cognitive, linguistic, and social skills, acquiring motor skills requires infants to generate their own input for learning. We tested factors that shape infants' spontaneous locomotion by observing forty 12- to 22-month-olds (19 girls, 21 boys) during free play. Infants were recruited from the New York City area, and caregivers reported that 25 infants were White, six were Asian, four were Black, and five had multiple races; four were Hispanic or Latino...
April 22, 2024: Developmental Psychology
#2
JOURNAL ARTICLE
Hugo Câmara-Costa, Lilia Tokpo, Leila Francillette, Hanna Toure, Dominique Brugel, Anne Laurent-Vannier, Philippe Meyer, Georges Dellatolas, Mathilde Chevignard
PURPOSE/OBJECTIVE: To investigate the occurrence of behavioral problems 7 years after severe pediatric traumatic brain injury (TBI), and their evolution from 3 months to 7 years postinjury. METHOD/DESIGN: Thirty-four participants, 38% girls, M ( SD ) age at injury 7.6 (4.7) years, age at assessment 15 (4.6) years, underwent comprehensive assessments 7 years after severe TBI from March 2014 to March 2016 and were matched to a control group by age, gender, and parental education...
April 22, 2024: Rehabilitation Psychology
#3
JOURNAL ARTICLE
Redoy Ranjan, Gie Ken-Dror, Ida Martinelli, Elvira Grandone, Sini Hiltunen, Erik Lindgren, Maurizio Margaglione, Veronique Le Cam Duchez, Aude Triquenot Bagan, Marialuisa Zedde, Nicola Giannini, Ynte M Ruigrok, Bradford B Worrall, Jennifer J Majersik, Jukka Putaala, Elena Haapaniemi, Susanna M Zuurbier, Matthijs C Brouwer, Serena M Passamonti, Maria Abbattista, Paolo Bucciarelli, Robin Lemmens, Emanuela Pappalardo, Paolo Costa, Marina Colombi, Diana Aguiar de Sousa, Sofia Rodrigues, Patrícia Canhão, Aleksander Tkach, Rosa Santacroce, Giovanni Favuzzi, Antonio Arauz, Donatella Colaizzo, Kostas Spengos, Amanda Hodge, Reina Ditta, Alessandro Pezzini, Jonathan M Coutinho, Vincent Thijs, Katarina Jood, Turgut Tatlisumak, José M Ferro, Pankaj Sharma
BACKGROUND AND PURPOSE: Coma is an independent predictor of poor clinical outcomes in cerebral venous thrombosis (CVT). We aimed to describe the association of age, sex, and radiological characteristics of adult coma patients with CVT. METHODS: We used data from the international, multicentre prospective observational BEAST (Biorepository to Establish the Aetiology of Sinovenous Thrombosis) study. Only positively associated variables with coma with <10% missing data in univariate analysis were considered for the multivariate logistic regression model...
April 22, 2024: European Journal of Neurology
#4
Habib Bouguenina, Stephanos Nicolaou, Yann-Vaï Le Bihan, Elizabeth A Bowling, Cheyenne Calderon, John J Caldwell, Brinley Harrington, Angela Hayes, P Craig McAndrew, Costas Mitsopoulos, Fernando Jr Sialana, Andrea Scarpino, Mark Stubbs, Arjun Thapaliya, Siddhartha Tyagi, Hannah Z Wang, Francesca Wood, Rosemary Burke, Florence Raynaud, Jyoti Choudhary, Rob L M van Montfort, Amine Sadok, Thomas F Westbrook, Ian Collins, Rajesh Chopra
[This corrects the article DOI: 10.1016/j.isci.2023.107059.].
May 17, 2024: IScience
#5
Rafael Everton Assunção Ribeiro da Costa, Maria Clara Amorim Silva, Erlan Clayton Xavier Cavalcante, Rodrigo de Oliveira Castelo Branco, Cristiane Amaral Dos Reis, Sabas Carlos Vieira
Granulosa cell tumor (GCT) is a rare ovarian malignancy that represents only 2-3% of all cases. There are two subtypes of GCT: juvenile/JGCT (5% of cases) and adult/AGCT (95% of cases). This study aimed to describe a series of 6 GCT cases. The 6 study patients were managed from June 2011 to November 2022 in a private oncology clinic located in Teresina (PI), Brazil. At diagnosis, the mean patient age was 47 years, and symptoms in 5 patients (83%) were pelvic pain and/or increased abdominal volume. The majority of the patients (N=4/67%) had no comorbidities or findings related to GCT on physical examination...
2024: Pan African Medical Journal
#6
Mafalda Batista da Costa, Harriet R Tenenbaum, Alexandra Grandison
The rise of feminist and LGBTQIA+ movements paved the way for many equality reforms. These include language reforms, which facilitate inclusion of multiple groups in society. For example, the shift from the generic "he" to "he or she" and "they" allows for the inclusion of women, transgender, and non-binary individuals in many narratives. For this reason, many institutions worldwide encourage neutral language. It remains unclear how individuals interpret neutral language. One case of neutral language is the pronoun "they," which has been assigned multiple definitions from the 1970s to 2022...
2024: Frontiers in Psychology
#7
JOURNAL ARTICLE
Rafael Hernán Mateus-Vargas, Verónica Arias-Pérez, Iván Sandoval-Hernández, Jens Andre Hammerl, Elías Barquero-Calvo
Apex predators are exposed to antimicrobial compounds and resistant microbes, which accumulate at different trophic levels of the related ecosystems. The study aimed to characterize the presence and the antimicrobial resistance patterns of fecal Escherichia coli isolated from cloacal swab samples obtained from wild-living American crocodiles ( Crocodylus acutus ) ( n = 53). Sampling was conducted within the distinctive context of a freshwater-intensive aquaculture farm in Costa Rica, where incoming crocodiles are temporarily held in captivity before release...
2024: Frontiers in Veterinary Science
#8
Valentina Frittitta, Giuliano Costa, Maria Teresa Cannizzaro, Cristina Inserra, Valeria Garretto, Elena Dipietro, Orazio Strazzieri, Silvia Motta, Marco Barbanti, Corrado Tamburino
Paravalvular regurgitation remains a frequent finding after transcatheter aortic valve replacement and is associated with unfavorable outcomes if more-than-mild grade. In this case, a patient underwent a third transcatheter aortic valve replacement procedure for worsening symptoms due to severe paravalvular regurgitation. The case underlines the role of preprocedural planning in achieving treatment success.
April 3, 2024: JACC. Case reports
#9
Caroline Filan, Seleipiri Charles, Paloma Casteleiro Costa, Weibo Niu, Brian F Cheng, Zhexing Wen, Hang Lu, Francisco E Robles
Brain organoids provide a unique opportunity to model organ development in a system similar to human organogenesis in vivo. Brain organoids thus hold great promise for drug screening and disease modeling. Conventional approaches to organoid characterization predominantly rely on molecular analysis methods, which are expensive, time-consuming, labor-intensive, and involve the destruction of the valuable 3D architecture of the organoids. This reliance on end-point assays makes it challenging to assess cellular and subcellular events occurring during organoid development in their 3D context...
April 1, 2024: Research Square
#10
JOURNAL ARTICLE
Mateus Rozalem Aranha, Victor Montal, Hilde van den Brink, Jordi Pegueroles, Maria Carmona-Iragui, Laura Videla, Lucia Maure Blesa, Bessy Benejam, Javier Arranz, Sílvia Valldeneu, Isabel Barroeta, Susana Fernández, Laia Ribas, Daniel Alcolea, Sofía González-Ortiz, Núria Bargalló, Geert Jan Biessels, Rafael Blesa, Alberto Lleó, Artur Martins Coutinho, Cláudia Costa Leite, Alexandre Bejanin, Juan Fortea
BACKGROUND: Cortical microinfarcts (CMI) were attributed to cerebrovascular disease and cerebral amyloid angiopathy (CAA). CAA is frequent in Down syndrome (DS) while hypertension is rare, yet no studies have assessed CMI in DS. METHODS: We included 195 adults with DS, 63 with symptomatic sporadic Alzheimer's disease (AD), and 106 controls with 3T magnetic resonance imaging. We assessed CMI prevalence in each group and CMI association with age, AD clinical continuum, vascular risk factors, vascular neuroimaging findings, amyloid/tau/neurodegeneration biomarkers, and cognition in DS...
April 21, 2024: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
#11
JOURNAL ARTICLE
Fernanda Oliveira Meller, Caroline Dos Santos Costa, Micaela Rabelo Quadra, Vanessa Iribarrem Avena Miranda, Fernanda Daminelli Eugênio, Tamara Justin da Silva, Maria Vitória Rodrigues Teixeira, Antônio Augusto Schäfer
The objective of this study is to evaluate the association between the consumption of ultra-processed foods (UPF) and the mental health of pregnant women from the South of Brazil. This is a cross-sectional study carried out in Criciúma, Brazil, through face-to-face interviews, from April to December 2022. Pregnant women aged 18 or older who underwent prenatal care in the 48 Basic Health Units of the municipality and who were in their third trimester of pregnancy were included. High consumption of UPF was considered as 6 or more items or subgroups of UPF consumed on the day before the interview, using the Nova-UPF screener...
April 22, 2024: British Journal of Nutrition
#12
JOURNAL ARTICLE
Andrés Benchetrit, Fernando Messina, Mario Matteo, Mariana Vázquez, Roxana Paul, Germán Gil Zbinden, Nora Costa, Gabriela Santiso
Pseudomycetomas are rare fungal subcutaneous infections caused by dermatophytes, which are mainly observed in immunocompromised patients. Mycobacterium genavense is considered an opportunistic pathogen in people living with HIV/AIDS (PLWHA), clinically resembling the presentation of Mycobacterium avium complex (MAC). Here, we describe the case of a 26-year-old PLWHA with a 3-month history of a 4cm tumoral, duroelastic and painful lesion located on the back. Histopathology of the tumoral lesion revealed chronic granulomatous inflammation with grains composed of PAS-positive and Grocott-positive septate hyphae, as well as acid-fast bacilli (AFB)...
April 20, 2024: Revista Argentina de Microbiología
#13
JOURNAL ARTICLE
Ana Carolina Prado Sousa, Adriane Suzin, Vinícius da Silva Rodrigues, Laís Miguel Rezende, Rodrigo da Costa Maia, Raíssa Brauner Kamla Vieira, Matias Pablo Juan Szabó
Wild boars or feral pigs are classified by the Brazilian Institute for the Environment and Renewable Resources (IBAMA) in "Category I of invasive exotic species". They cause economic losses, harm the environment, serve as hosts and reservoirs for several zoonotic disease agents, and provide a blood meal for tick species that act as vectors for zoonotic diseases. The objective of this study was to identify tick species on wild boars, assess host-seeking ticks in the related environment, and identify other potential tick hosts coexisting with wild boars on a farm located in the state of Minas Gerais, southeastern Brazil...
May 2024: Veterinary Parasitology (Amsterdam)
#14
JOURNAL ARTICLE
Marloes Franssen, Juul Achten, Duncan Appelbe, Matthew L Costa, Susan Dutton, James Mason, Jenny Gould, Andrew Gray, Amar Rangan, Warren Sheehan, Harvinder Singh, Stephen E Gwilym
AIMS: Fractures of the humeral shaft represent 3% to 5% of all fractures. The most common treatment for isolated humeral diaphysis fractures in the UK is non-operative using functional bracing, which carries a low risk of complications, but is associated with a longer healing time and a greater risk of nonunion than surgery. There is an increasing trend to surgical treatment, which may lead to quicker functional recovery and lower rates of fracture nonunion than functional bracing. However, surgery carries inherent risk, including infection, bleeding, and nerve damage...
April 22, 2024: Bone & joint open
#15
REVIEW
Alvaro Umaña Quesada
The paper focuses on the failure to account for the value of standing tropical forests, and of ecosystem services in general, in economic decision-making. This blindness to the values of nature has led to overexploitation, degradation and destruction of tropical forests, which, in turn, has also significantly contributed to greenhouse gas emissions. Forest conservation and restoration has a critical role to play in the fight against climate change and brings a vast array of additional benefits, from security in water, energy, food, health and livelihoods to maintaining biodiversity itself as a core component of our living planet...
June 10, 2024: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
#16
REVIEW
Christina Morgenstern, Isabel Lastres-Becker, Birsen Can Demirdöğen, Vera Marisa Costa, Andreas Daiber, Roberta Foresti, Roberto Motterlini, Sibel Kalyoncu, Burak I Arioz, Sermin Genc, Monika Jakubowska, Ioannis P Trougakos, Aleksandra Piechota-Polanczyk, Michel Mickael, Marlene Santos, Thomas W Kensler, Antonio Cuadrado, Ian M Copple
The cytoprotective transcription factor NRF2 regulates the expression of several hundred genes in mammalian cells and is a promising therapeutic target in a number of diseases associated with oxidative stress and inflammation. Hence, an ability to monitor basal and inducible NRF2 signalling is vital for mechanistic understanding in translational studies. Due to some caveats related to the direct measurement of NRF2 levels, the modulation of NRF2 activity is typically determined by measuring changes in the expression of one or more of its target genes and/or the associated protein products...
March 30, 2024: Redox Biology
#17
JOURNAL ARTICLE
Maria Miguel Coelho, Inês Costa, Ana Carolina Ferreira de Albuquerque, Fernando Martins Dos Santos Junior, Bárbara Silva, Renata Silva, Carla Fernandes, Fernando Remião, Maria Elizabeth Tiritan
The misuse of pharmaceuticals has significantly increased in recent decades, becoming a major public health concern. The risks associated with medication misuse are particularly high in cases of overdose, especially when the active substances are chiral, as enantioselectivity plays an important role in toxicity. Promethazine (PMZ) is a chiral antihistamine marketed as a racemate and it is misused in "Purple Drank", a recreational drug beverage, that combines codeine and/or PMZ, with soda or alcohol leading to serious health consequences and fatalities in consumers around the world, particularly among teenagers...
April 15, 2024: Journal of Pharmaceutical and Biomedical Analysis
#18
REVIEW
Anne Cathrine Staff, Maria Laura Costa, Ralf Dechend, Daniel P Jacobsen, Meryam Sugulle
Cardiovascular disease (CVD) is globally the leading cause of death and disability. Sex-specific causes of female CVD are under-investigated. Pregnancy remains an underinvestigated sex-specific stress test for future CVD and a hitherto missed opportunity to initiate prevention of CVD at a young age. Population-based studies show a strong association between female CVD and hypertensive disorders of pregnancy. This association is also present after other pregnancy complications that are associated with placental dysfunction, including fetal growth restriction, preterm delivery and gestational diabetes mellitus...
April 20, 2024: Pregnancy Hypertension
#19
JOURNAL ARTICLE
Thiago S Oliveira, Hericles M Campos, Rafael M Costa, Raphaela C Georg, Jacqueline A Leite, Rita C Tostes, Elson A Costa, Fernanda Cristina A Santos, Núbia S Lobato, Fernando P Filgueira, Paulo César Ghedini
Estrone (E1) constitutes the primary component in oral conjugated equine estrogens (CEEs) and serves as the principal estrogen precursor in the female circulation in the post-menopause. E1 induces endothelium-dependent vasodilation and activate PI3K/NO/cGMP signaling. To assess whether E1 mitigates vascular dysfunction associated with postmenopause and explore the underlying mechanisms, we examined the vascular effects of E1 in ovariectomized (OVX) rats, a postmenopausal experimental model. Blood pressure was measured using tail-cuff plethysmography, and aortic rings were isolated to assess responses to phenylephrine, acetylcholine (ACh), and sodium nitroprusside...
April 21, 2024: Naunyn-Schmiedeberg's Archives of Pharmacology
#20
JOURNAL ARTICLE
Nicole Felix, Paula C Nogueira, Isadora M Silva, Thomaz Alexandre Costa, Carlos Alberto Campello, Carlos Stecca, Renato D Lopes
INTRODUCTION: Several interventions have been tested for cardio-protection against anthracycline-induced cancer therapy-related cardiovascular dysfunction (CTRCD). The role of statins in this setting remains unclear. METHODS: We systematically searched PubMed, Embase, Cochrane Library, Clinicaltrials.gov, and Web of Science for randomized controlled trials (RCTs) comparing statins versus control (placebo or no intervention) for preventing anthracycline-induced CTRCD...
April 19, 2024: European Journal of Internal Medicine
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