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https://www.readbyqxmd.com/read/29333076/parenchyma-sparing-hepatectomy-psh-versus-non-psh-for-bilobar-liver-metastases-of-colorectal-cancer
#1
Lidewij Spelt, Daniel Ansari, Max Swanling, Peter Holka, Roland Andersson
Background: Preoperative interventions have increased the resectability of colorectal cancer (CRC) liver metastases. This retrospective study compares outcomes after liver resection for bilobar CRC metastases between patients who underwent parenchyma-sparing hepatectomy (PSH), i.e., segmentectomies and smaller resections on both lobes, and those treated with non-PSH, i.e., hemihepatectomy plus any resection on the other lobe. Methods: A cohort of 119 patients who underwent liver resection for bilobar CRC metastases were included...
January 2018: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/29330681/verification-of-nonwords-the-baseword-frequency-effect-in-children-s-pseudohomophone-reading
#2
Simon P Tiffin-Richards, Sascha Schroeder
In this study, we investigated the baseword frequency effect in children and its implications for models of visual word recognition. The baseword frequency effect reflects the finding that response latencies in the lexical decision task to nonwords derived from high-frequency basewords (e.g., GREAN derived from GREEN) are shorter than for those derived from low-frequency basewords (e.g., SLEAT derived from SLEET). Importantly, the baseword frequency effect presents a challenge to current activation-based models of visual word recognition...
January 12, 2018: Psychonomic Bulletin & Review
https://www.readbyqxmd.com/read/29326089/associations-between-markers-of-oxidative-stress-skeletal-muscle-mass-and-function-and-to-the-influence-of-resistance-exercise-training-in-older-adults
#3
Ciriaco Carru, Mariasole Da Boit, Panagiotis Paliogiannis, Angelo Zinellu, Salvatore Sotgia, Rachael Sibson, Judith R Meakin, Richard M Aspden, Arduino A Mangoni, Stuart R Gray
BACKGROUND: Oxidative stress (OS) negatively affects skeletal muscle homeostasis in experimental models of ageing. However, little is known about the associations between circulating OS markers and parameters of muscle mass and function, and their responses to exercise training, in humans. METHODS: Maximal voluntary contraction (MVC, primary outcome) and isokinetic torque of the knee extensors at 30° s-1 (MIT), muscle cross-sectional area (MCSA) and quality (MQ, secondary outcomes), and plasma concentrations of malondialdehyde (MDA, pro-OS), homocysteine (HCY, pro-OS), taurine (TAU, anti-OS), and protein sulphydryl groups (PSH, anti-OS) were measured in 27 healthy older males and 23 females at baseline and after an 18-week resistance exercise program, with or without a nutritional intervention (fish oil vs...
January 8, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29304111/combined-bulked-segregant-sequencing-and-traditional-linkage-analysis-for-identification-of-candidate-gene-for-purple-leaf-sheath-in-maize
#4
Pengcheng Li, Cancan Du, Yingying Zhang, Shuangyi Yin, Enying Zhang, Huimin Fang, Dezhou Lin, Chenwu Xu, Zefeng Yang
Anthocyanin accumulation in various maize tissues plays important roles in plant growth and development. In addition, some color-related traits can be used as morphological markers in conventional maize breeding processes and purity identification of hybrid seeds. Here, we noticed that the leaf sheath color was controlled by a dominant gene, because purple (PSH) and green leaf sheaths (GSH) were separated at a ratio of 3:1 in an F2 population. To map the gene, an F2 and a recombinant inbred line (RIL) population were derived from a cross between inbred line T877 (PSH) and DH1M (GSH)...
2018: PloS One
https://www.readbyqxmd.com/read/29295625/anti-hydroxyl-radical-activity-redox-potential-and-anti-ache-activity-of-amanita-strobiliformis-polysaccharide-extract
#5
Maja Karaman, Ljiljana Janjušević, Dragica Jakovljević, Filip Šibul, Boris Pejin
This study outlines antioxidant and anti-AChE activities of the polysaccharide (PSH) extract from the mushroom species Amanita strobiliformis. Both the presence of α and ß glucans within the aforementioned extract was recorded. PSH extract displayed a profound scavenging activity of OH radicals (IC50 value, 11.86 ± 0.59 μg/mL) and high potential for reduction of Fe3+ ions (174.11 ± 8.70 mg eq. AA/g d.w.) being almost 48- and 5-fold more effective than mannitol and butylated hydroxytoluene used as a positive control, respectively...
January 2, 2018: Natural Product Research
https://www.readbyqxmd.com/read/29195290/static-field-gradient-polarizabilities-of-small-atoms-and-molecules-at-finite-temperature
#6
Juha Tiihonen, Ilkka Kylänpää, Tapio T Rantala
In this work, we propose new field-free estimators of static field-gradient polarizabilities for finite temperature path-integral Monte Carlo method. Namely, dipole-quadrupole polarizability A, dipole-dipole-quadrupole polarizability B, and quadrupole-quadrupole polarizability C are computed for several up to two-electron systems: H, H-, He, Li+, Be2+, Ps2, PsH, H2+, H2, H3+, and HeH+. We provide complementary data for ground state electronic properties within the adiabatic approximation and demonstrate good agreement with available values in the literature...
November 28, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29187690/-treatment-for-paroxysmal-sympathetic-hyperactivity-in-amyotrophic-lateral-sclerosis-patient
#7
Katsunori Yokoi, Tetsuo Ando, Sawao Ishikawa
We report a case of an 80-year-old man who contracted amyotrophic lateral sclerosis (ALS) 15 years ago, was put on a ventilator 8 years ago, and became locked in 3 years ago. Two years ago, he began to suffer from sudden symptoms of paroxysmal sympathetic hyperactivity (PSH) attacks (hot flushes, abnormal sweating, tachycardia, and increased blood pressure). One day, he developed multiple-organ failure. This failure healed in a few days, but PSH attacks remained. His catecholamine levels were abnormal: adrenaline, 215 pg/ml; noradrenaline, 5,960 pg/ml; and dopamine, 606 pg/ml...
December 27, 2017: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/29183036/surgical-approach-to-right-hepatic-core-deepest-region-surrounded-by-major-portal-pedicles-and-right-hepatic-vein
#8
Keigo Tani, Takeaki Ishizawa, Yoshihiro Sakamoto, Kiyoshi Hasegawa, Norihiro Kokudo
BACKGROUND/AIMS: The resection of hepatic tumors located in the region surrounded by the right hepatic vein (RHV) and the portal pedicles of the right paramedian/lateral sector (the right hepatic core) remains a challenge for liver surgeons. The aim of this study was to demonstrate the surgical techniques and outcomes of our atypical-parenchyma-sparing hepatectomy (atypical-PSH) approach for the removal of tumors in the right hepatic core. METHODS: Perioperative records of 1,179 consecutive patients who had undergone hepatectomy for hepatocellular carcinoma or colorectal liver metastases from January 2006 to December 2014 were retrospectively reviewed...
November 28, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/29166776/the-polysaccharide-extracts-from-the-fungi-coprinus-comatus-and-coprinellus-truncorum-do-exhibit-ache-inhibitory-activity
#9
Boris Pejin, Kristina Tešanović, Dragica Jakovljević, Sonja Kaišarević, Filip Šibul, Milena Rašeta, Maja Karaman
The polysaccharide (PSH) extracts from the edible mushroom species Coprinus comatus and Coprinellus truncorum were screened in liquid for their acetylcholinesterase inhibitory (AChE) activity. Both extracts were found to display inhibition of the aforementioned enzyme reaching similar IC50 values of 0.62 ± 0.07 and 0.61 ± 0.03 mg/mL, respectively. According to the means of FTIR spectroscopy, these PSH extracts mostly contained β-glucans. However, the presence of some proteins and polyphenolics as minor ingredients were also detected...
November 22, 2017: Natural Product Research
https://www.readbyqxmd.com/read/29151238/predictability-of-hypoadrenalism-occurrence-and-duration-after-adrenalectomy-for-acth-independent-hypercortisolism
#10
V Morelli, L Minelli, C Eller-Vainicher, S Palmieri, E Cairoli, A Spada, M Arosio, I Chiodini
OBJECTIVE: To evaluate if the parameters of hypothalamic-pituitary-adrenal (HPA) axis activity could predict the occurrence and duration of post-surgical hypocortisolism (PSH) in patients with Cushing's syndrome (CS) and with adrenal incidentaloma (AI). METHODS: We studied 80 patients (54 females, age 53.3 ± 11 years), who underwent adrenalectomy for CS (17 patients) or for AI (53 patients). Before surgery, we measured adrenocorticotroph hormone (ACTH), urinary free cortisol (UFC) and serum cortisol after 1 mg dexamethasone suppression test (1 mg-DST) levels...
November 18, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/29147959/port-site-hernia-after-laparoscopic-sleeve-gastrectomy-a-retrospective-cohort-study-of-352-patients
#11
Ilhan Ece, Huseyin Yilmaz, Husnu Alptekin, Serdar Yormaz, Bayram Colak, Mustafa Sahin
Port site hernia (PSH) following laparoscopic procedures is a rare but serious complication. The aim of this study was to evaluate the rate of PSH after laparoscopic sleeve gastrectomy (LSG), and the efficacy of closure of the port site as a means of preventing PSH. A retrospective analysis was performed on 386 patients who underwent LSG between December 2009 and January 2015. 352 (91.2%) of the patient were followed up for at least 24 months. In the first 206 patients, the fascial layers of the trocar incisions were not closed, while in the next 146 cases, routine closure of the trocar sites was performed...
November 16, 2017: Updates in Surgery
https://www.readbyqxmd.com/read/29112196/understanding-the-roles-of-mutations-in-the-amyloid-precursor-protein-in-alzheimer-disease
#12
REVIEW
S Hunter, C Brayne
Many models of disease progression in Alzheimer's disease (AD) have been proposed to help guide experimental design and aid the interpretation of results. Models focussing on the genetic evidence include the amyloid cascade (ACH) and presenilin (PSH) hypotheses and the amyloid precursor protein (APP) matrix approach (AMA), of which the ACH has held a dominant position for over two decades. However, the ACH has never been fully accepted and has not yet delivered on its therapeutic promise. We review the ACH, PSH and AMA in relation to levels of APP proteolytic fragments reported from AD-associated mutations in APP...
November 7, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/29112167/overexpression-of-a-new-chitinase-gene-euchit2-enhances-resistance-to-erysiphe-cichoracearum-dc-in-tobacco-plants
#13
Xuan Dong, Yichen Zhao, Xin Ran, Linxia Guo, De-Gang Zhao
In this study, we cloned a new chitinase gene, EuCHIT2, from Eucommia ulmoides Oliver (E. ulmoides) using rapid amplification of cDNA ends (RACE) technology and constructed an overexpression vector, pSH-35S-EuCHIT2, to introduce it into tobacco (Nicotiana tabacum cv. Xanthi). Resistance to Erysiphe cichoracearum de Candolle (E.cichoracearum DC) and molecular mechanisms in the transgenic tobacco were determined by drop inoculation, spore counting, determination of physicochemical indicators, and analysis of gene expression...
November 7, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29064900/use-of-prophylactic-mesh-when-creating-a-colostomy-does-not-prevent-parastomal-hernia-a-randomized-controlled-trial-stomamesh
#14
Christoffer Odensten, Karin Strigård, Jörgen Rutegård, Michael Dahlberg, Ulrika Ståhle, Ulf Gunnarsson, Pia Näsvall
OBJECTIVE: The aim of this study was to determine whether parastomal hernia (PSH) rate can be reduced by using synthetic mesh in the sublay position when constructing permanent end colostomy. The secondary aim was to investigate possible side-effects of the mesh. BACKGROUND: Prevention of PSH is important as it often causes discomfort and leakage from stoma dressing. Different methods of prevention have been tried, including several mesh techniques. The incidence of PSH is high; up to 78%...
October 23, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/29052472/extraction-and-reliable-determination-of-acrylamide-from-thermally-processed-foods-using-ionic-liquid-based-ultrasound-assisted-selective-microextraction-combined-with-spectrophotometry
#15
Nail Altunay, Adil Elik, Ramazan Gürkan
Acrylamide (AAm) is a carcinogenic chemical that can form in thermally processed foods by the Maillard reaction of glucose with asparagine. AAm can easily be formed especially in frequently consumed chips and cereal-based foods depending on processing conditions. Considering these properties of AAm, a new, simple and green method is proposed for the extraction of AAm from thermally processed food samples. In this study, an ionic liquid (1-butyl-3-methylimidazolium tetrafluoroborate, [Bmim][BF4]) as extractant was used in the presence of a cationic phenazine group dye, 3,7-diamino-5-phenylphenazinium chloride (PSH(+), phenosafranine) at pH 7...
October 31, 2017: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29032372/parenchymal-sparing-surgery-for-the-surgical-treatment-of-multiple-colorectal-liver-metastases-is-a-safer-approach-than-major-hepatectomy-not-impairing-patients-prognosis-a-bi-institutional-propensity-score-matched-analysis
#16
Matteo Donadon, Matteo Cescon, Alessandro Cucchetti, Matteo Cimino, Guido Costa, Benedetta Pesi, Giorgio Ercolani, Antonio Daniele Pinna, Guido Torzilli
BACKGROUND: The performance of parenchymal-sparing hepatectomy (PSH) versus major hepatectomy (MH) in patients with multiple colorectal liver metastases (CLM) is a matter that is yet debated. We investigated the outcome of patients with multiple CLM undergoing PSH instead of MH. METHODS: Databases at 2 institutions were reviewed. A propensity score-matched analysis was applied. Among 554 patients, 110 undergoing PSH and 110 undergoing MH were matched. They were similar in baseline characteristics, comorbidity, and tumor features...
October 14, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/29028454/the-longtan-modification-an-effective-and-economical-surgical-innovation-for-parastomal-hernia-post-intraperitoneal-sigmoidostomy
#17
Peng Wang, Hao Su, Jianwei Liang, Zheng Wang, Zhixiang Zhou, Haitao Zhou
PURPOSE: This study was designed to introduce a new surgical innovation, referred to as the "Longtan modification," for cases with parastomal hernia (PSH) following intraperitoneal sigmoidostomy, and to assess the safety and feasibility of this procedure. METHODS: Between January 2013 and June 2016, a total of 26 consecutive cases with PSH successfully underwent this procedure. The patient demographics, surgical outcomes, stoma-related complications, and the stoma function were collected and analyzed...
October 13, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28984074/availability-of-comprehensive-services-in-permanent-supportive-housing-in-los-angeles
#18
Benjamin F Henwood, Taylor Harris, Darlene Woo, Hailey Winetrobe, Harmony Rhoades, Suzanne L Wenzel
Studies have often described a specific model or models of permanent supportive housing (PSH), yet few studies have systematically examined what services are typically offered to PSH tenants in any given service system and how those services are offered. Using telephone surveys from 23 PSH agency supervisors and qualitative data collected from 11 focus groups with 60 frontline providers and 17 individual interviews with supervisors from a subset of surveyed agencies-all of which were completed between July 2014 and December 2015-the goal of this study is to better understand what services are being offered in PSH organisations located in Los Angeles and what barriers frontline providers face in delivering these services...
October 6, 2017: Health & Social Care in the Community
https://www.readbyqxmd.com/read/28978176/dexmedetomidine-attenuates-acute-paroxysmal-sympathetic-hyperactivity
#19
Yuan Peng, Haifeng Zhu, Haodong Chen, Zijin Zhu, Huahai Zhou, Shuguang Zhang, Lili Gao, Lei Shi, Xiaoliang Li, Zhengxiang Luo
We evaluated the curative effect of dexmedetomidine on paroxysmal sympathetic hyperactivity (PSH) in a retrospective study of 72 PSH patients after neurosurgery. Our results showed that dexmedetomidine was superior to propofol for treatment of PSH with respect to: average time needed to reduce paroxysmal hypertension (PH) to <140/90 mmHg (29.03±8.86 vs. 42.0±14.77 min), average remission time of PH (3.97±1.73 vs. 5.65±1.51 min), PH remission rate (61.22±10.8% vs. 41.52±14.15%), PH duration (9.31±2...
September 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28964298/implementation-of-a-perioperative-surgical-home-protocol-for-pediatric-patients-presenting-for-adenoidectomy
#20
Vidya T Raman, Dmitry Tumin, Joshua Uffman, Arlyne K Thung, Candice Burrier, Kris R Jatana, Charles Elmaraghy, Joseph D Tobias
INTRODUCTION: The perioperative surgical home (PSH) is a patient-centered model designed to improve health, streamline the delivery of health care, and reduce the cost of care. Following the national introduction of PSH in 2014 by the ASA, adult hospitals have reported success with this model, with studies validating the benefits of PSH including reducing length of stay, lowering costs, and improving patient satisfaction. METHODS: Eligible patients, ranging in age from 16-35 months of age, were identified by the pre-admission testing (PAT) registered nurses (RNs) and faculty anesthesiologists upon review of the patient history...
October 2017: International Journal of Pediatric Otorhinolaryngology
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