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https://www.readbyqxmd.com/read/29326456/case-report-coronectomy-of-an-impacted-and-submerged-second-deciduous-molar
#1
M G Hussain, S K Sah, I McHenry
Coronectomy is a widely-accepted technique available for the treatment of impacted wisdom teeth. The fundamental principle is to prevent trauma to the inferior dental nerve (IDN). Many publications have demonstrated its positive outcomes but there is no literature available regarding coronectomy of deciduous teeth. This case report highlights the complex approach to managing a severely infraoccluded 85 in the mixed dentition of a 10-year-old female. The report demonstrates and discusses the combined orthodontic and oral surgical approach to prevent damage to the IDN and to allow space for orthodontic movement...
January 12, 2018: British Dental Journal
https://www.readbyqxmd.com/read/29325955/endovascular-patch-embolization-for-blood-blister-like-aneurysms-in-the-dorsal-segment-of-the-internal-carotid-artery
#2
Xudong Hao, Guilin Li, Jian Ren, Jingwei Li, Chuan He, Hong-Qi Zhang
OBJECTIVE: Blood blister-like aneurysms (BBAs) in the dorsal segment of the internal carotid artery (ICA) are fragile and difficult to treat, and the optimal treatment for BBAs is still controversial. We report clinical and angiographic results with procedural details for the treatment of BBA by using the endovascular patch embolization method. METHODS: We retrospectively reviewed patients who presented with subarachnoid hemorrhage(SAH) caused by ICA-BBAs and were treated with the endovascular patch embolization method in our center from October 2011 to March 2015...
January 8, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29325889/early-cell-response-of-osteogenic-cells-on-differently-modified-implant-surfaces-sequences-of-cell-proliferation-adherence-and-differentiation
#3
Sebastian Blatt, Andreas Max Pabst, Eik Schiegnitz, Marco Hosang, Thomas Ziebart, Christian Walter, Bilal Al-Nawas, Marcus Oliver Klein
OBJECTIVES: Osseointegration of dental implants is a crucial prerequisite for long-term survival. Therefore, surface modifications are needed to interact with the extracellular environment and to trigger osteogenic cell responses such as cell proliferation, adherence, and differentiation. The purpose of this study was to investigate different surface modifications in vitro over 2 weeks. MATERIALS AND METHODS: Commercially available cells from a human osteogenic cell line (HHOB-c) were cultivated on the following surfaces: titanium with smooth surfaces (polished titanium (P), machined titanium (M), polyetheretherketone (Peek)), titanium with rough and hydrophilised surfaces (acid etched titanium (A), sandblasted acid etched titanium (SA and SA2), sandblasted acid etched hydrophilised (SAH), titanium plasma painted titanium (TPS)), titanium with calcium phosphate-containing surfaces (titanium plasma painted calcium phosphate modified titanium (TPS-CaP), sandblasted calcium phosphate modified titanium (S-CaP), sandblasted acid etched calcium phosphate modified titanium (SA-CaP)), and zirconium-oxide (yttrium amplified zirconium (Z), yttrium amplified Ca2+ delivering zirconium (Z-Ca))...
December 26, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29325587/human-echinostomiasis-a-case-report
#4
Ranjit Sah, Shusila Khadka, Rabin Hamal, Sagar Poudyal
BACKGROUND: Echinostomiasis is a food-borne infection caused by an intestinal trematodes belonging to the family Echinostomatidae. They infect the gastrointestinal tract of humans. Patients are usually asymptomatic. However, with heavy infections, the worms can produce catarrhal inflammation with mild ulceration and the patient may experience abdominal pain, anorexia, nausea, vomiting, diarrhea and weight loss. Infection are associated with common sociocultural practices of eating raw or insufficiently cooked mollusks and fish...
January 11, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29325471/intracranial-subarachnoid-hemorrhage-following-cervical-laminoplasty-a-report-of-two-cases
#5
Yuichi Kondo, Kazunari Fushimi, Makoto Takasawa, Shigeo Kanamori, Takaki Miyagawa, Kenji Kawashima, Kazutoshi Yokoyama, Haruhiko Akiyama
Intracranial hemorrhage is a rare complication of spinal surgery. Case 1 was a 58-year-old man who underwent cervical laminoplasty. No apparent iatrogenic dural rupture or cerebrospinal fluid leakage was observed. An hour after the surgery, the patient had convulsions and became restless thereafter. CT revealed an intracranial SAH. The patient recovered normal consciousness the next morning. Case 2 was a 68-year-old woman who underwent cervical laminoplasty without postoperative CSF leakage. Six days after the surgery, the patient continued to complain of nausea and headache...
January 12, 2018: International Journal of Neuroscience
https://www.readbyqxmd.com/read/29323183/delivery-of-xenon-containing-echogenic-liposomes-inhibits-early-brain-injury-following-subarachnoid-hemorrhage
#6
Yi-Feng Miao, Tao Peng, Melanie R Moody, Melvin E Klegerman, Jaroslaw Aronowski, James Grotta, David D McPherson, Hyunggun Kim, Shao-Ling Huang
Xenon (Xe), a noble gas, has promising neuroprotective properties with no proven adverse side-effects. We evaluated neuroprotective effects of Xe delivered by Xe-containing echogenic liposomes (Xe-ELIP) via ultrasound-controlled cerebral drug release on early brain injury following subarachnoid hemorrhage (SAH). The Xe-ELIP structure was evaluated by ultrasound imaging, electron microscopy and gas chromatography-mass spectroscopy. Animals were randomly divided into five groups: Sham, SAH, SAH treated with Xe-ELIP, empty ELIP, or Xe-saturated saline...
January 11, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29322973/facial-nerve-schwannomas-a-case-series-with-an-analysis-of-imaging-findings
#7
Shambhu K Sah, You You Guo, Nirajan Mahaseth, Yanlin Chen, Silin Du, Yongmei Li
Facial nerve schwannomas (FNSs) are rare benign tumors arising from the Schwann cells of the sheath of the facial nerve. These tumors may arise anywhere along the course of the facial nerve. Owing to their rarity and nonspecific clinical and radiological presentations, the preoperative diagnosis of FNSs is exceedingly difficult. In this study, we present four cases of histopathologically proven extratemporal schwannomas and a solitary case of intratemporal schwannoma. The purpose of this study was mainly focused on analyzing the imaging findings of extratemporal and intratemporal schwannomas in an effort to better characterize these lesions preoperatively...
January 2018: Neurology India
https://www.readbyqxmd.com/read/29313314/duration-of-agitation-fluctuations-of-consciousness-and-associations-with-outcome-in-patients-with-subarachnoid-hemorrhage
#8
Michael E Reznik, Ali Mahta, J Michael Schmidt, Hans-Peter Frey, Soojin Park, David J Roh, Sachin Agarwal, Jan Claassen
BACKGROUND: Agitation is common after subarachnoid hemorrhage (SAH) and may be independently associated with outcomes. We sought to determine whether the duration of agitation and fluctuating consciousness were also associated with outcomes in patients with SAH. METHODS: We identified all patients with positive Richmond Agitation Sedation Scale (RASS) scores from a prospective observational cohort of patients with SAH from 2011 to 2015. Total duration of agitation was extrapolated for each patient using available RASS scores, and 24-h mean and standard deviation (SD) of RASS scores were calculated for each patient...
January 8, 2018: Neurocritical Care
https://www.readbyqxmd.com/read/29311276/species-specific-interactions-of-arr-with-rplk-mediate-stringent-response-in-bacteria
#9
Priyanka Agrawal, Rajagopal Varada, Shivjee Sah, Souvik Bhattacharyya, Umesh Varshney
Bacteria respond to stressful growth conditions through a conserved phenomenon of 'stringent response' mediated by synthesis of stress alarmones, ppGpp or pppGpp [referred to as (p)ppGpp]. The (p)ppGpp synthesis is known to occur by ribosome associated RelA. In addition, a dual function protein SpoT (with both the synthetase and hydrolase activities) maintains (p)ppGpp homeostasis. The presence of (p)ppGpp is also known to contribute to antibiotic resistance in bacteria. Mycobacterium smegmatis possesses Arr, which inactivates rifampicin by its ADP-ribosylation...
January 8, 2018: Journal of Bacteriology
https://www.readbyqxmd.com/read/29310519/intranasal-stem-cell-treatment-as-a-novel-therapy-for-subarachnoid-hemorrhage
#10
Cora H Nijboer, Elke Kooijman, Cindy T van Velthoven, Erik Van Tilborg, Ivo A Tiebosch, Niels Eijkelkamp, Rick M Dijkhuizen, Jozef Kesecioglu, Cobi Heijnen
Subarachnoid hemorrhage (SAH) represents a major health problem in Western society due to high mortality and morbidity, and the relative young age of patients. Currently, efficacious therapeutic options are very limited. Mesenchymal stem cell (MSC) administration has been shown to improve functional outcome and lesion size in experimental models of stroke and neonatal hypoxic-ischemic brain injury. Here we studied the therapeutic potential of intranasally administered bone marrow-derived MSCs relatively late post-insult using a rat endovascular puncture model for SAH...
January 8, 2018: Stem Cells and Development
https://www.readbyqxmd.com/read/29309312/the-link-between-cerebrovascular-hemodynamics-and-rehabilitation-outcomes-after-aneurysmal-subarachnoid-hemorrhage
#11
Forrest A Brooks, Uvieoghene Ughwanogho, Galen V Henderson, Randie Black-Schaffer, Farzaneh A Sorond, Can Ozan Tan
OBJECTIVE: To assess the relation between cerebrovascular function early after aneurysmal subarachnoid hemorrhage (SAH) onset and functional and rehabilitation outcomes. DESIGN: Observational cohort study of SAH patients (n=133) admitted to rehabilitation (n=49), discharged home (n=52), or died before discharge (n=10). Hemodynamic markers of cerebral autoregulatory function obtained from blood flow velocities in the middle cerebral artery and arterial pressure waveforms, recorded daily on days 2-4 after symptom onset, and functional independence measure (FIM™) scores and FIM efficiency for those admitted to acute rehabilitation...
January 5, 2018: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/29306849/verbal-learning-and-memory-outcome-in-selective-amygdalohippocampectomy-versus-temporal-lobe-resection-in-patients-with-hippocampal-sclerosis
#12
Mette Thrane Foged, Kirsten Vinter, Louise Stauning, Troels W Kjær, Brice Ozenne, Sándor Beniczky, Olaf B Paulson, Flemming Find Madsen, Lars H Pinborg
PURPOSE: With the advent of new very selective techniques like thermal laser ablation to treat drug-resistant focal epilepsy, the controversy of resection size in relation to seizure outcome versus cognitive deficits has gained new relevance. The purpose of this study was to test the influence of the selective amygdalohippocampectomy (SAH) versus nonselective temporal lobe resection (TLR) on seizure outcome and cognition in patients with mesial temporal lobe epilepsy (MTLE) and histopathological verified hippocampal sclerosis (HS)...
January 4, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29305915/intraventricular-hemorrhage-due-to-subarachnoid-hemorrhage-does-the-severity-matter
#13
Marvin Darkwah Oppong, Oliver Gembruch, Annika Herten, Roman Frantsev, Mehdi Chihi, Philipp Dammann, Nicolai El Hindy, Michael Forsting, Ulrich Sure, Ramazan Jabbarli
OBJECT: Aneurysm rupture might be accompanied by intraventricular hemorrhage (IVH) that is associated with poor outcome of subarachnoid hemorrhage (SAH). The aim of this study was to analyze risk factors and clinical impact of IVH severity. MATERIAL AND METHODS: 995 consecutive SAH patients treated at our institution between January 2003 and June 2016 were eligible for this study. Clinical and radiological findings were correlated with the presence and severity of IVH assessed with the original Graeb score...
January 3, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29302787/pediatric-abusive-head-trauma-in-taiwan-clinical-characteristics-and-risk-factors-associated-with-mortality
#14
An-Lun Wu, Lai-Chu See, Shao-Hsuan Hsia, Hui-Tzu Tu, Nan-Kai Wang, Jing-Long Huang, Yih-Shiou Hwang, Chi-Chun Lai, Wei-Chi Wu
PURPOSE: To report the clinical characteristics of abusive head trauma (AHT) in Taiwan and identify the risk factors associated with mortality of these patients. METHODS: Children with clinically diagnosed AHT from January 1, 2000, to October 31, 2015 were reviewed. The demographic data, clinical features, and associated retinal and radiologic findings were analyzed. The multivariable logistic regression model analysis was performed to identify the risk factors associated with in-hospital mortality...
January 4, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29301852/potein-kinase-g-activation-reverses-oxidative-stress-and-restores-osteoblast-function-and-bone-formation-in-male-mice-with-type-1-diabetes
#15
Hema Kalyanaraman, Gerburg Schwaerzer, Ghania Ramdani, Francine Castillo, Brian T Scott, Wolfgang Dillmann, Robert L Sah, Darren E Casteel, Renate B Pilz
Bone loss and fractures are under-recognized complications of type 1 diabetes, and are primarily due to impaired bone formation by osteoblasts. The mechanisms leading to osteoblast dysfunction in diabetes are incompletely understood, but insulin deficiency, poor glycemic control, and hyperglycemia-induced oxidative stress likely contribute. Here we show that insulin promotes osteoblast proliferation and survival via the nitric oxide (NO)/cGMP/protein kinase G (PKG) signal transduction pathway, and that PKG stimulation of Akt provides a positive feedback loop...
January 4, 2018: Diabetes
https://www.readbyqxmd.com/read/29296615/minocycline-protects-against-delayed-cerebral-ischemia-after-subarachnoid-hemorrhage-via-matrix-metalloproteinase-9-inhibition
#16
Ananth K Vellimana, Meng-Liang Zhou, Itender Singh, Diane J Aum, James W Nelson, Glenn R Harris, Umeshkumar Athiraman, Byung H Han, Gregory J Zipfel
Objective: Delayed cerebral ischemia (DCI) is an independent risk factor for poor outcome after aneurysmal subarachnoid hemorrhage (SAH) and is multifactorial in etiology. While prior studies have suggested a role for matrix metalloproteinase-9 (MMP-9) in early brain injury after SAH, its contribution to the pathophysiology of DCI is unclear. Methods: In the first experiment, wild-type (WT) and MMP-9-/- mice were subjected to sham or endovascular perforation SAH surgery...
December 2017: Annals of Clinical and Translational Neurology
https://www.readbyqxmd.com/read/29295925/evolution-of-real-contact-area-under-shear-and-the-value-of-static-friction-of-soft-materials
#17
R Sahli, G Pallares, C Ducottet, I E Ben Ali, S Al Akhrass, M Guibert, J Scheibert
The frictional properties of a rough contact interface are controlled by its area of real contact, the dynamical variations of which underlie our modern understanding of the ubiquitous rate-and-state friction law. In particular, the real contact area is proportional to the normal load, slowly increases at rest through aging, and drops at slip inception. Here, through direct measurements on various contacts involving elastomers or human fingertips, we show that the real contact area also decreases under shear, with reductions as large as 30[Formula: see text], starting well before macroscopic sliding...
January 2, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29291402/chop-induces-apoptosis-by-affecting-brain-iron-metabolism-in-rats-with-subarachnoid-hemorrhage
#18
Jun Zhao, Xiang Xiang, Hongxia Zhang, Dengzhi Jiang, Yidan Liang, Wang Qing, Liu Liu, Qing Zhao, Zhaohui He
The endoplasmic reticulum stress-related factor CCAAT/enhancer binding protein (C/EBP) homologous protein (CHOP) aggravates early brain injury (EBI) in rats after subarachnoid hemorrhage (SAH). Our research aims to investigate the role of CHOP-mediated iron metabolism in EBI after SAH and the underlying mechanism. Male Sprague-Dawley rats were used to establish SAH models. Tunicamycin (Tm) was employed to excite CHOP expression, and two CHOP small interfering RNAs (siRNAs) were used to inhibit CHOP expression...
December 29, 2017: Experimental Neurology
https://www.readbyqxmd.com/read/29290070/one-hour-postoperative-parathyroid-hormone-levels-do-not-reliably-predict-hypocalcemia-after-thyroidectomy
#19
Zeyad Sahli, Alireza Najafian, Stacie Kahan, Eric B Schneider, Martha A Zeiger, Aarti Mathur
INTRODUCTION: Hypocalcemia is a well-known complication after total thyroidectomy. Studies have indicated that the presence of low postoperative parathyroid hormone (PTH) levels can predict hypocalcemia. However, definitive study designs are lacking. The aim of this study was to determine whether postoperative PTH alone can accurately predict postoperative biochemical hypocalcemia. METHODS: Under IRB approval, a prospective study of 218 consecutive patients who underwent total or completion thyroidectomy by two surgeons between June 2014 and June 2016 was performed...
December 31, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29284999/high-burden-of-stroke-risk-factors-in-developing-country-the-case-study-of-bosnia-herzegovina
#20
Marija Bender, Edin Jusufovic, Vesna Railic, Sima Kelava, Selma Tinjak, Damir Dzevdetbegovic, Dario Mot, Mensuda Tresnjo, Sandra Lakicevic, Natasa Pejanovic-Skobic, Osman Sinanovic
Introduction: The burden of stroke has been increasing worldwide, especially in developing countries. Very few data regarding epidemiology of stroke are available in Bosnia and Herzegovina (BH). Patients and methods: We undertook a retrospective hospital-based study in all hospitals existing in five cantons and one district of BH. The patients were recruited between January 1st, 2014, and December 31st, 2014, and only first-ever-in-lifetime strokes (FES) were included for evaluation...
December 2017: Materia Socio-medica
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