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https://www.readbyqxmd.com/read/28925375/modelling-the-effect-of-electrode-displacement-on-transcranial-direct-current-stimulation-tdcs
#1
Sriharsha Ramaraju, Mohammed Ali Roula, Peter McCarthy
Transcranial Direct Current Stimulation (tDCS) is a neuromodulatory technique that delivers a low-intensity, direct current to cortical areas with the purpose of modulating underlying brain activity. Recent studies have reported inconsistencies in tDCS outcomes. The underlying assumption of many tDCS studies has been that replication of electrode montage equates to replicating stimulation conditions. It is possible however that anatomical difference between subjects, as well as inherent inaccuracies in montage placement, could affect current flow to targeted areas...
September 19, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28921774/modulating-vicarious-tactile-perception-with-transcranial-electrical-current-stimulation
#2
Natalie C Bowling, Michael J Banissy
Our capacity to share the experiences of others is a critical part of social behaviour. One process thought to be important for this is vicarious perception. Passively viewing touch activates some of the same network of brain regions as the direct experience of touch. This vicarious experience is usually implicit, but for some people, viewing touch evokes conscious tactile sensations (mirror-touch synaesthesia). Recent work has attempted to induce conscious vicarious touch in those that do not normally experience these sensations, using transcranial direct current stimulation (tDCS)...
September 16, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28917592/prefrontal-versus-motor-cortex-transcranial-direct-current-stimulation-tdcs-effects-on-post-surgical-opioid-use
#3
Jeffrey J Borckardt, Scott T Reeves, Cole Milliken, Brittan Carter, Thomas I Epperson, Ryan J Gunselman, Alok Madan, H Del Schutte, Harry A Demos, Mark S George
BACKGROUND: Pain is often a complaint that precedes total knee arthroplasty (TKA), however the procedure itself is associated with considerable post-operative pain lasting days to weeks which can predict longer-term surgical outcomes. Previously, we reported significant opioid-sparing effects of motor cortex transcranial direct current stimulation from a single-blind trial. In the present study, we used double-blind methodology to compare motor cortex tDCS and prefrontal cortex tDCS to both sham and active-control (active electrodes over non-pain modulating brain areas) tDCS...
September 6, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28917591/increased-left-prefrontal-brain-perfusion-after-mri-compatible-tdcs-attenuates-momentary-ruminative-self-referential-thoughts
#4
Chris Baeken, Jonathan Remue, Marie-Anne Vanderhasselt, Andre R Brunoni, Sara De Witte, Romain Duprat, Ernst H W Koster, Rudi De Raedt, Guo-Rong Wu
BACKGROUND: Transcranial direct current stimulation (tDCS) is a non-invasive electrical stimulation technique, assumed to influence cognition and emotional processing. OBJECTIVE: However, it is unclear how tDCS influences spontaneous cognitive processes such as momentary self-referential thoughts on the neuronal level. METHODS: Forty healthy female volunteers participated in a single session sham-controlled crossover tDCS study while being in the MRI scanner...
September 6, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28912542/transcranial-direct-current-stimulation-tdcs-applied-to-the-left-dorsolateral-premotor-cortex-dpmc-interferes-with-rhythm-reproduction
#5
B Pollok, C L Overhagen, A Keitel, V Krause
Movement timing in the sub-second range engages a brain network comprising cortical and sub-cortical areas. The present study aims at investigating the functional significance of the left dorsolateral premotor cortex (dPMC) for precise movement timing as determined by sensorimotor synchronization and rhythm reproduction. To this end, 18 healthy volunteers performed an auditorily paced synchronization-continuation task with the right hand. A simple reaction time task served as control condition. Transcranial direct current stimulation (tDCS) was applied over the left dPMC in order to modulate cortical excitability either with anodal or cathodal polarity or as sham stimulation...
September 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28906348/effect-of-anodal-transcranial-direct-current-stimulation-of-the-motor-cortex-on-elbow-flexor-muscle-strength-in-the-very-old
#6
Kentaro Oki, Leatha A Clark, Shinichi Amano, Brian C Clark
BACKGROUND AND PURPOSE: Muscle weakness predisposes older adults to a fourfold increase in functional limitations and has previously been associated with reduced motor cortex excitability in aging adults. The purpose of this study was to determine whether a single session of anodal transcranial direct current stimulation (tDCS) of the motor cortex would increase elbow flexion muscle strength and electromyographic (EMG) amplitude in very old individuals. METHODS: Eleven very old individuals-85...
September 12, 2017: Journal of Geriatric Physical Therapy
https://www.readbyqxmd.com/read/28903772/transcranial-direct-current-stimulation-tdcs-for-improving-capacity-in-activities-and-arm-function-after-stroke-a-network-meta-analysis-of-randomised-controlled-trials
#7
REVIEW
Bernhard Elsner, Gert Kwakkel, Joachim Kugler, Jan Mehrholz
BACKGROUND: Transcranial Direct Current Stimulation (tDCS) is an emerging approach for improving capacity in activities of daily living (ADL) and upper limb function after stroke. However, it remains unclear what type of tDCS stimulation is most effective. Our aim was to give an overview of the evidence network regarding the efficacy and safety of tDCS and to estimate the effectiveness of the different stimulation types. METHODS: We performed a systematic review of randomised trials using network meta-analysis (NMA), searching the following databases until 5 July 2016: Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, CINAHL, AMED, Web of Science, and four other databases...
September 13, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28902872/anodal-transcranial-direct-current-stimulation-of-the-right-anterior-temporal-lobe-did-not-significantly-affect-verbal-insight
#8
Takatsugu Aihara, Takeshi Ogawa, Takeaki Shimokawa, Okito Yamashita
Humans often utilize past experience to solve difficult problems. However, if past experience is insufficient to solve a problem, solvers may reach an impasse. Insight can be valuable for breaking an impasse, enabling the reinterpretation or re-representation of a problem. Previous studies using between-subjects designs have revealed a causal relationship between the anterior temporal lobes (ATLs) and non-verbal insight, by enhancing the right ATL while inhibiting the left ATL using transcranial direct current stimulation (tDCS)...
2017: PloS One
https://www.readbyqxmd.com/read/28892581/direct-current-stimulation-modulates-the-excitability-of-the-sensory-and-motor-fibres-in-the-human-posterior-tibial-nerve-with-a-long-lasting-effect-on-the-h-reflex
#9
Francesco Bolzoni, Roberto Esposti, Carlo Bruttini, Giuseppe Zenoni, Elzbieta Jankowska, Paolo Cavallari
Several studies demonstrated that transcutaneous direct current stimulation (DCS) may modulate CNS excitability. However, much less is known about how DC affects peripheral nerve fibres. We investigated the action of DCS on motor and sensory fibres of the human posterior tibial nerve, with supplementary analysis in acute experiments on rats. In forty human subjects, electric pulses at the popliteal fossa were used to elicit either M-waves or H-reflexes in the Soleus, before (15 min), during (10 min) and after (30 min) DCS...
September 11, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28889119/sham-transcranial-electrical-stimulation-and-its-effects-on-corticospinal-excitability-a-systematic-review-and-meta-analysis
#10
Thusharika D Dissanayaka, Maryam Zoghi, Michael Farrell, Gary F Egan, Shapour Jaberzadeh
Sham stimulation is used in randomized controlled trials (RCTs) to assess the efficacy of active stimulation and placebo effects. It should mimic the characteristics of active stimulation to achieve blinding integrity. The present study was a systematic review and meta-analysis of the published literature to identify the effects of sham transcranial electrical stimulation (tES) - including anodal and cathodal transcranial direct current stimulation (a-tDCS, c-tDCS), transcranial alternating current stimulation (tACS), transcranial random noise stimulation (tRNS) and transcranial pulsed current stimulation (tPCS) - on corticospinal excitability (CSE), compared to baseline in healthy individuals...
September 11, 2017: Reviews in the Neurosciences
https://www.readbyqxmd.com/read/28887641/interference-effects-of-transcranial-direct-current-stimulation-over-the-right-frontal-cortex-and-adrenergic-system-on-conditioned-fear
#11
Mohammad Nasehi, Reyhaneh Soltanpour, Mohaddeseh Ebrahimi-Ghiri, Shahram Zarrabian, Mohammad-Reza Zarrindast
RATIONALE: The effects of pharmacological interventions on fear memory have widely been studied, but there are very few studies about the effects of brain electrical stimulation on fear memory function. OBJECTIVE: Therefore, our aim was to determine whether anodal/cathodal transcranial direct current stimulation (tDCS) over the right frontal cortex would modify propranolol-induced contextual and auditory fear memory deficits, before or after training. METHODS: The adult NMRI male mice were randomly assigned into three groups: the sham group, the anodal tDCS group, and the cathodal tDCS group...
September 8, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28885111/effects-of-different-montages-of-transcranial-direct-current-stimulation-on-the-risk-of-falls-and-lower-limb-function-after-stroke
#12
Suellen Marinho Andrade, José Jamacy de Almeida Ferreira, Thatiana Silva Rufino, Germana Medeiros, Jader Duarte Brito, Michele Alexandre da Silva, Raquel de Negreiros Moreira
BACKGROUND: Stroke is associated with high rates of falling and severe impairment of lower limb in patients who survive. OBJECTIVE: The aim of this study was to analyze the effectiveness of different montages of transcranial direct current stimulation (tDCS) on reducing falls and on lower limb function after acute stroke. METHODS: Sixty participants with acute stroke were randomly allocated into four groups with different electrode's setups: anodal, cathodal, bilateral and sham tDCS...
September 8, 2017: Neurological Research
https://www.readbyqxmd.com/read/28884523/response-of-umbilical-cord-mesenchymal-stromal-cells-to-varying-titanium-topographical-signals
#13
Ines Lauria, Miriam Höner, Sebastian Kant, Roswitha Davtalab, Thomas Weik, Katrin Sternberg, Horst Fischer
A wide variety of titanium implant modifications have been developed to improve tissue- or cell-material interactions including bone bonding, implant failure, and contact osteogenesis. Osteogenesis can be stimulated by mechanobiological signals such as topography though translation of in vivo reactions to in vitro bioactivity and stem cell culture data, and vice versa, is challenging. We hypothesized that a systematic in vitro approach comparing clinically well-accepted implant surface topographical modifications could shed light on potential cell biological mechanisms provoked by submicron-, micron- or macrostructured surfaces...
September 7, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28878714/modulating-the-activity-of-the-dlpfc-and-ofc-has-distinct-effects-on-risk-and-ambiguity-decision-making-a-tdcs-study
#14
Xiaolan Yang, Mei Gao, Jinchuan Shi, Hang Ye, Shu Chen
Human beings are constantly exposed to two types of uncertainty situations, risk and ambiguity. Neuroscientific studies suggest that the dorsolateral prefrontal cortex (DLPFC) and the orbital frontal cortex (OFC) play significant roles in human decision making under uncertainty. We applied the transcranial direct current stimulation (tDCS) device to modulate the activity of participants' DLPFC and OFC separately, comparing the causal relationships between people's behaviors and the activity of the corresponding brain cortex when confronted with situations of risk and ambiguity...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28877142/adding-prefrontal-transcranial-direct-current-stimulation-before-occipital-nerve-stimulation-in-fibromyalgia
#15
Hye Bin Yoo, Jan Ost, Wim Joos, Tony Van Havenbergh, Dirk De Ridder, Sven Vanneste
OBJECTIVES: Fibromyalgia is a type of chronic musculoskeletal pain without a clear peripheral origin of nociception, often associated with depression. The underlying pathophysiology involves changes in a functional network that is related to pain and emotional processing in the central nervous system. Transcranial direct current stimulation (tDCS) targeting the dorsolateral prefrontal cortex or the occipital nerve (ON) are non-invasive neuromodulation techniques capable of improving fibromyalgia symptoms...
September 1, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28870510/repeated-transcranial-direct-current-stimulation-improves-cognitive-dysfunction-and-synaptic-plasticity-deficit-in-the-prefrontal-cortex-of-streptozotocin-induced-diabetic-rats
#16
Yi-Jen Wu, Chou-Ching Lin, Che-Ming Yeh, Miao-Er Chien, Ming-Chung Tsao, Philip Tseng, Chin-Wei Huang, Kuei-Sen Hsu
BACKGROUND: Cognitive dysfunction is commonly observed in diabetic patients. We have previously reported that anodal transcranial direct current stimulation (tDCS) over the dorsolateral prefrontal cortex can facilitate visuospatial working memory in diabetic patients with concomitant diabetic peripheral neuropathy and mild cognitive impairment, but the underlying mechanisms remain unclear. OBJECTIVE: We investigated the cellular mechanisms underlying the effect of tDCS on cognitive decline in streptozotocin (STZ)-induced diabetic rats...
August 24, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28868196/novel-approach-to-continuous-neurophysiological-monitoring-during-surgery-of-peripheral-nerve-tumors
#17
Ángel Saponaro-González, Pedro Javier Pérez-Lorensu
BACKGROUND: Intraoperative neurophysiological monitoring (IONM) with nerve action potential (NAP) can be useful during peripheral nerve surgery. However, current methodologies are not optimized for continuous recording of the NAP. The use of newer electrodes may make it possible to more conveniently obtain continuous recordings of the NAP during surgery. METHODS: After localizing the nerve of interest and dissecting it from the adjacent soft tissue, two APS(®) (Automatic Periodic Stimulation) electrodes, originally designed for stimulation of the vagus nerve during thyroid surgery, are placed on the nerve on either sides of the tumor for stimulation and recording using two subdermal electroencephalogram (EEG) needles as anode and reference, respectively...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28868118/effects-of-left-prefrontal-transcranial-direct-current-stimulation-on-the-acquisition-of-contextual-and-cued-fear-memory
#18
Shahsanam Abbasi, Mohammad Nasehi, Hamid Reza Soleimanpour Lichaei, Mohammad-Reza Zarrindast
OBJECTIVES: Behavioral and neuroimaging studies have shown that transcranial direct current stimulation, as a non-invasive neuromodulatory technique, beyond regional effects can modify functionally interconnected remote cortical and subcortical areas. In this study, we hypothesized that the induced changes in cortical excitability following the application of cathodal or anodal tDCS over the left frontal cortex as pre-training would affect functional connectivity in resting-state circuits of fear memory and consequently could improve or disturb the acquisition of fear memory...
June 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28866447/efficacy-of-fronto-temporal-transcranial-direct-current-stimulation-for-refractory-auditory-verbal-hallucinations-in-schizophrenia-a-randomized-double-blind-sham-controlled-study
#19
Anushree Bose, Venkataram Shivakumar, Sri Mahavir Agarwal, Sunil V Kalmady, Sonia Shenoy, Vanteemar S Sreeraj, Janardhanan C Narayanaswamy, Ganesan Venkatasubramanian
Persistent auditory verbal hallucinations (AVH) that are refractory to antipsychotic medications are reported in about 20-30% of schizophrenia patients. Transcranial Direct Current Stimulation (tDCS), a non-invasive and safe neuromodulatory technique, has attracted significant interest as an add-on treatment for refractory AVH in schizophrenia. Studies examining the efficacy of tDCS for refractory AVH in schizophrenia have reported inconsistent findings. In this study, using a randomized, double-blind, sham-controlled design (RCT), we sought to examine the effect of add-on tDCS [anode corresponding to left dorsolateral prefrontal cortex and cathode to left temporo-parietal junction; 2-mA, twice-daily sessions for 5-days] to treat refractory AVH in schizophrenia patients (N=25); following this RCT phase, patients that had <30% reduction in AVH severity were offered an open-label extension (OLE) active stimulation to evaluate the effect of cross-over to verum tDCS...
August 30, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28864916/effects-of-transcranial-direct-current-stimulation-on-the-auditory-mismatch-negativity-response-and-working-memory-performance-in-schizophrenia-a-pilot-study
#20
Danielle Impey, Ashley Baddeley, Renee Nelson, Alain Labelle, Verner Knott
Cognitive impairment has been proposed to be the core feature of schizophrenia (Sz). Transcranial direct current stimulation (tDCS) is a non-invasive form of brain stimulation which can improve cognitive function in healthy participants and in psychiatric patients with cognitive deficits. tDCS has been shown to improve cognition and hallucination symptoms in Sz, a disorder also associated with marked sensory processing deficits. Recent findings in healthy controls demonstrate that anodal tDCS increases auditory deviance detection, as measured by the brain-based event-related potential, mismatch negativity (MMN), which is a putative biomarker of Sz that has been proposed as a target for treatment of Sz cognition...
September 1, 2017: Journal of Neural Transmission
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