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https://www.readbyqxmd.com/read/29350775/randomized-trial-of-transcranial-dc-stimulation-for-post-stroke-dysphagia
#1
Sonja Suntrup-Krueger, Corinna Ringmaier, Paul Muhle, Andreas Wollbrink, Andre Kemmling, Uta Hanning, Inga Claus, Tobias Warnecke, Inga Teismann, Christo Pantev, Rainer Dziewas
OBJECTIVE: We evaluated whether transcranial direct current stimulation (tDCS) is able to enhance dysphagia rehabilitation following stroke. Besides relating clinical effects with neuroplastic changes in cortical swallowing processing we aimed to identify factors influencing treatment success. METHODS: In this double-blind, randomized study 60 acute dysphagic stroke patients received contralesional anodal (1 mA, 20 min) or sham tDCS on four consecutive days. Swallowing function was thoroughly assessed before and after the intervention using the validated Fiberoptic Endoscopic Dysphagia Severity Scale (FEDSS) and clinical assessment...
January 19, 2018: Annals of Neurology
https://www.readbyqxmd.com/read/29336898/effect-of-transcranial-direct-current-stimulation-on-short-term-and-long-term-treatment-of-chronic-tinnitus
#2
Hamidreza Abtahi, Ahmadreza Okhovvat, Somaiie Heidari, Azar Gharagazarloo, Motahare Mirdamadi, Mohammad Hossein Nilforoush, Hossein Ghazavi
OBJECTIVE: This study was conducted to investigate the effectiveness of anodal and cathodal methods in reducing the intensity of tinnitus and to compare them with the control. METHODOLOGY: This randomized double-blind clinical trial with case and control groups was conducted in Al-Zahra Hospital in Isfahan between 2015 and 2016. In this trial, 51 patients with tinnitus, for at least one year, were selected among those outpatients visiting the throat, nose and ear clinic within this period...
January 6, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/29335751/transcranial-direct-current-stimulation-enhances-foot-sole-somatosensation-when-standing-in-older-adults
#3
Junhong Zhou, On-Yee Lo, Lewis A Lipsitz, Jue Zhang, Jing Fang, Brad Manor
Foot-sole somatosensation is critical for safe mobility in older adults. Somatosensation arises when afferent input activates a neural network that includes the primary somatosensory cortex. Transcranial direct current stimulation (tDCS), as a strategy to increase somatosensory cortical excitability, may, therefore, enhance foot-sole somatosensation. We hypothesized that a single session of tDCS would improve foot-sole somatosensation, and thus mobility, in older adults. Twenty healthy older adults completed this randomized, double-blinded, cross-over study consisting of two visits separated by one week...
January 15, 2018: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/29335430/transspinal-direct-current-stimulation-produces-persistent-plasticity-in-human-motor-pathways
#4
Lynda M Murray, Behdad Tahayori, Maria Knikou
The spinal cord is an integration center for descending, ascending, and segmental neural signals. Noninvasive transspinal stimulation may thus constitute an effective method for concomitant modulation of local and distal neural circuits. In this study, we established changes in cortical excitability and input/output function of corticospinal and spinal neural circuits before, at 0-15 and at 30-45 minutes after cathodal, anodal, and sham transspinal direct current stimulation (tsDCS) to the thoracic region in healthy individuals...
January 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29330825/poststimulation-time-interval-dependent-effects-of-motor-cortex-anodal-tdcs-on-reaction-time-task-performance
#5
Andrés Molero-Chamizo, José R Alameda Bailén, Tamara Garrido Béjar, Macarena García López, Inmaculada Jaén Rodríguez, Carolina Gutiérrez Lérida, Silvia Pérez Panal, Gloria González Ángel, Laura Lemus Corchero, María J Ruiz Vega, Michael A Nitsche, Guadalupe N Rivera-Urbina
Anodal transcranial direct current stimulation (tDCS) induces long-term potentiation-like plasticity, which is associated with long-lasting effects on different cognitive, emotional, and motor performances. Specifically, tDCS applied over the motor cortex is considered to improve reaction time in simple and complex tasks. The timing of tDCS relative to task performance could determine the efficacy of tDCS to modulate performance. The aim of this study was to compare the effects of a single session of anodal tDCS (1...
January 12, 2018: Cognitive, Affective & Behavioral Neuroscience
https://www.readbyqxmd.com/read/29329367/effects-of-anodal-transcranial-direct-current-stimulation-over-the-ventrolateral-prefrontal-cortex-on-episodic-memory-formation-and-retrieval
#6
Angela Medvedeva, Maurizio Materassi, Victorita Neacsu, Jesssica Beresford-Webb, Aya Hussin, Naghma Khan, Felix Newton, Giulia Galli
In the past decade, several studies have investigated the effects of transcranial direct current stimulation (tDCS) on episodic memory abilities. However, the specific conditions under which tDCS affects memory remain largely unclear. Here, we report data from 4 experiments aimed at investigating the effects of anodal tDCS over the left ventrolateral prefrontal cortex (VLPFC) on verbal episodic memory. We evaluated tDCS-induced effects as a function of time of administration, nature of the memory encoding task, and age of the participants...
January 10, 2018: Cerebral Cortex
https://www.readbyqxmd.com/read/29329154/effects-on-volume-load-and-ratings-of-perceived-exertion-in-individuals-advanced-weight-training-after-transcranial-direct-current-stimulation
#7
Eduardo Lattari, Blair José Rosa Filho, Sidnei Jorge Fonseca Junior, Eric Murillo-Rodriguez, Nuno Rocha, Sérgio Machado, Geraldo Albuquerque Maranhão Neto
The aim of this study was investigate the effects of transcranial direct current stimulation (tDCS) on volume-load and ratings of perceived exertion. Fifteen young healthy individuals, aged between 20 and 30 years in advanced strength training were recruited. Test and retest of the 10 maximum repetitions (10RM) were performed to determine the reliability of load utilized. Subjects performed three experimental conditions in a randomized, double-blinded crossover design: anodic stimulation (a-tDCS), cathodic stimulation (c-tDCS) and sham (2 mA for 20 minutes targeting the dorsolateral prefrontal cortex cortex left)...
January 11, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29317605/non-invasive-modulation-reduces-repetitive-behavior-in-a-rat-model-through-the-sensorimotor-cortico-striatal-circuit
#8
Henriette Edemann-Callesen, Bettina Habelt, Franziska Wieske, Mark Jackson, Niranjan Khadka, Daniele Mattei, Nadine Bernhardt, Andreas Heinz, David Liebetanz, Marom Bikson, Frank Padberg, Ravit Hadar, Michael A Nitsche, Christine Winter
Involuntary movements as seen in repetitive disorders such as Tourette Syndrome (TS) results from cortical hyperexcitability that arise due to striato-thalamo-cortical circuit (STC) imbalance. Transcranial direct current stimulation (tDCS) is a stimulation procedure that changes cortical excitability, yet its relevance in repetitive disorders such as TS remains largely unexplored. Here, we employed the dopamine transporter-overexpressing (DAT-tg) rat model to investigate behavioral and neurobiological effects of frontal tDCS...
January 10, 2018: Translational Psychiatry
https://www.readbyqxmd.com/read/29301545/personalized-upper-limb-training-combined-with-anodal-tdcs-for-sensorimotor-recovery-in-spastic-hemiparesis-study-protocol-for-a-randomized-controlled-trial
#9
Mindy F Levin, Melanie C Baniña, Silvi Frenkel-Toledo, Sigal Berman, Nachum Soroker, John M Solomon, Dario G Liebermann
BACKGROUND: Recovery of voluntary movement is a main rehabilitation goal. Efforts to identify effective upper limb (UL) interventions after stroke have been unsatisfactory. This study includes personalized impairment-based UL reaching training in virtual reality (VR) combined with non-invasive brain stimulation to enhance motor learning. The approach is guided by limiting reaching training to the angular zone in which active control is preserved ("active control zone") after identification of a "spasticity zone"...
January 4, 2018: Trials
https://www.readbyqxmd.com/read/29301026/cerebellar-transcranial-direct-current-stimulation-improves-procedural-learning-in-nonclinical-psychosis-a-double-blind-crossover-study
#10
Tina Gupta, Derek J Dean, Nicholas J Kelley, Jessica A Bernard, Ivanka Ristanovic, Vijay A Mittal
The present double-blind crossover study examines the effects of cerebellar transcranial direct current stimulation (tDCS) in controls and in an analogue population to psychosis: individuals reporting elevated symptoms of nonclinical psychosis (NCP). A total of 18 controls and 24 NCP individuals were randomized into conditions consisting of 25 minutes of anodal (active) or sham cerebellar tDCS. Following this, both groups completed a pursuit rotor task designed to measure procedural learning performance. Participants then returned 1-week later and received the corresponding condition (either active or sham) and repeated the pursuit rotor task...
December 30, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29288683/what-is-difficult-for-you-can-be-easy-for-me-effects-of-increasing-individual-task-demand-on-prefrontal-lateralization-a-tdcs-study
#11
A Vergallito, Leonor J Romero Lauro, Rolando Bonandrini, Laura Zapparoli, Laura Danelli, Manuela Berlingeri
Neuroimaging studies suggest that increment of the cognitive load associated with a specific task may induce the recruitment of a more bilateral brain network. In most studies, however, task demand has been manipulated in a static and pre-specified way, regardless of individual cognitive resources. Here we implemented a new paradigm based on a pre-experimental assessment to set up subject-specific levels of task demand and applied tDCS (transcranial direct current stimulation) to assess each hemisphere involvement in task performance...
December 27, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/29283556/nanochannels-photoelectrochemical-biosensor
#12
Nan Zhang, Yi-Fan Ruan, Li-Bin Zhang, Wei-Wei Zhao, Jing-Juan Xu, Hong-Yuan Chen
Nanochannels have brought new opportunities for biosensor development. Herein we present the novel concept of nanochannels photoelectrochemical (PEC) biosensor based on the integration of a unique CuxO nanopyramid islands (NPIs) photocathode, the anodic aluminum oxide (AAO) membrance, and the alkaline phosphatase (ALP) catalytic chemistry. The CuxO NPIs photocathode possessed good performance, and further assembly with AAO will yield the designed architecture composed of vertically-aligned, highly-ordered nanoarrays bottomed with CuxO NPIs film...
December 28, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29282470/efficacy-and-safety-of-transcranial-direct-current-stimulation-as-an-add-on-treatment-for-bipolar-depression-a-randomized-clinical-trial
#13
Bernardo Sampaio-Junior, Gabriel Tortella, Lucas Borrione, Adriano H Moffa, Rodrigo Machado-Vieira, Eric Cretaz, Adriano Fernandes da Silva, Renério Fraguas, Luana V Aparício, Izio Klein, Beny Lafer, Stephan Goerigk, Isabela Martins Benseñor, Paulo Andrade Lotufo, Wagner F Gattaz, André Russowsky Brunoni
Importance: More effective, tolerable interventions for bipolar depression treatment are needed. Transcranial direct current stimulation (tDCS) is a novel therapeutic modality with few severe adverse events that showed promising results for unipolar depression. Objective: To determine the efficacy and safety of tDCS as an add-on treatment for bipolar depression. Design, Setting, and Participants: A randomized, sham-controlled, double-blind trial (the Bipolar Depression Electrical Treatment Trial [BETTER]) was conducted from July 1, 2014, to March 30, 2016, at an outpatient, single-center academic setting...
December 27, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/29259570/galvanic-tongue-stimulation-inhibits-five-basic-tastes-induced-by-aqueous-electrolyte-solutions
#14
Kazuma Aoyama, Kenta Sakurai, Satoru Sakurai, Makoto Mizukami, Taro Maeda, Hideyuki Ando
Galvanic tongue stimulation (GTS) modulates taste sensation. However, the effect of GTS is contingent on the electrode polarity in the proximity of the tongue. If an anodal electrode is attached in the proximity of the tongue, an electrical or metallic taste is elicited. On the other hand, if only cathodal electrode is attached in the proximity of the tongue, the salty taste, which is induced by electrolyte materials, is inhibited. The mechanism of this taste inhibition is not adequately understood. In this study, we aim to demonstrate that the inhibition is cause by ions, which elicit taste and which migrate from the taste sensors on the tongue by GTS...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29259554/strengthening-of-existing-episodic-memories-through-non-invasive-stimulation-of-prefrontal-cortex-in-older-adults-with-subjective-memory-complaints
#15
Rosa Manenti, Marco Sandrini, Elena Gobbi, Chiara Cobelli, Michela Brambilla, Giuliano Binetti, Maria Cotelli
Episodic memory is critical to daily life functioning. This type of declarative memory declines with age and is the earliest cognitive function to be compromised in Alzheimer's disease (AD). Subjective memory complaints are commonly reported by older adults and have been considered a risk factor for developing AD. The possibilities for prevention of memory disorders in older adults have increased substantially in recent years. Previous studies have shown that anodal transcranial Direct Current Stimulation (tDCS) applied over the left lateral prefrontal cortex (PFC) after a contextual reminder strengthened existing verbal episodic memories, conceivably through reconsolidation, in elderly people...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29249932/no-interaction-between-tdcs-current-strength-and-baseline-performance-a-conceptual-replication
#16
Gemma Learmonth, Francesca Felisatti, Numaya Siriwardena, Matthew Checketts, Christopher S Y Benwell, Gesine Märker, Gregor Thut, Monika Harvey
Several recent studies have reported non-linear effects of transcranial direct current stimulation (tDCS), which has been attributed to an interaction between the stimulation parameters (e.g., current strength, duration) and the neural state of the cortex being stimulated (e.g., indexed by baseline performance ability, age) (see Fertonani and Miniussi, 2016). We have recently described one such non-linear interaction between current strength and baseline performance on a visuospatial attention (landmark) task (Benwell et al...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29249931/preliminary-evidence-of-other-race-effect-like-behavior-induced-by-cathodal-tdcs-over-the-right-occipital-cortex-in-the-absence-of-overall-effects-on-face-object-processing
#17
Andrea I Costantino, Matilde Titoni, Francesco Bossi, Isabella Premoli, Michael A Nitsche, Davide Rivolta
Neuromodulation techniques such as tDCS have provided important insight into the neurophysiological mechanisms that mediate cognition. Albeit anodal tDCS (a-tDCS) often enhances cognitive skills, the role of cathodal tDCS (c-tDCS) in visual cognition is largely unexplored and inconclusive. Here, in a single-blind, sham-controlled study, we investigated the offline effects of 1.5 mA c-tDCS over the right occipital cortex of 86 participants on four tasks assessing perception and memory of both faces and objects...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29248858/cathodal-electrical-stimulation-of-frontoparietal-cortex-disrupts-statistical-learning-of-visual-configural-information
#18
Abbey S Nydam, David K Sewell, Paul E Dux
Attentional performance is facilitated by exploiting regularities and redundancies in the environment by way of incidental statistical learning. For example, during visual search, response times to a target are reduced by repeating distractor configurations-a phenomenon known as contextual cueing (Chun & Jiang, 1998). A range of neuroscientific methods have provided evidence that incidental statistical learning relies on subcortical neural structures associated with long-term memory, such as the hippocampus...
November 22, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/29245151/substantial-enhancement-of-anaerobic-pyridine-bio-mineralization-by-electrical-stimulation
#19
Xinbai Jiang, Jinyou Shen, Kaichun Xu, Dan Chen, Yang Mu, Xiuyun Sun, Weiqing Han, Jiansheng Li, Lianjun Wang
Due to highly recalcitrant and toxicological nature of pyridine, the conventional anaerobic bioprocess is often limited by low removal rate and poor process stability. In this study, an electricity-assisted anaerobic system was developed in order to enhance biodegradation of pyridine from wastewater. The results showed that the performance and stability of the anaerobic reactor was remarkably improved for pyridine biodegradation with the applied direct current of 0.3 mA, where the efficiencies of pyridine and total organic carbon removal as well as NH4+-N formation were as high as 100...
December 5, 2017: Water Research
https://www.readbyqxmd.com/read/29242502/impact-of-electrode-position-on-the-elicitation-of-sodium-spikes-in-retinal-bipolar-cells
#20
Frank Rattay, Hassan Bassereh, Andreas Fellner
Bipolar cells of the magnocellular pathway in the primate retina can generate action potentials because they have an axonal segment with high sodium channel density, comparable to the sodium channel band in retinal ganglion cells or pyramidal cells. The similarity between the non-human primate and the human retina is of interest for the research on retinal implants for the blind, and especially, the conditions to elicit sodium spikes in bipolar cells using extracellular stimulation. A comparison of excitation characteristics of three model neurons, a bipolar cell, a retinal ganglion cell, and a cortical pyramidal cell, demonstrates the similarities and differences regarding stimulation with microelectrodes...
December 14, 2017: Scientific Reports
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