keyword
MENU ▼
Read by QxMD icon Read
search

dupuytren treatment

keyword
https://www.readbyqxmd.com/read/29157019/patients-needs-during-a-surgical-intervention-process-for-dupuytren-s-disease
#1
Christina Turesson, Joanna Kvist, Barbro Krevers
PURPOSE: To explore and describe clients' needs during a surgical intervention process for Dupuytren's disease. MATERIALS AND METHODS: Design: Interview study with 21 men undergoing surgical intervention for Dupuytren's disease. Qualitative content analysis was performed with the model of Patient Evaluation Process as a theoretical framework. RESULTS: The primary reason for seeking medical care was to receive an intervention to improve hand function...
November 21, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29103246/dupuytren-s-contracture-current-treatment-methods
#2
REVIEW
Guy Feldman, Nimrod Rozen, Guy Rubin
Dupuytren's disease is a common benign fibromatosis of the palmar and digital fascia. The exact pathophysiology and epidemiology of this condition have not been entirely identified. Pathologic fibrous bands cause a flexion contracture of the metacarpal phalangeal joints and proximal interphalangeal joint. Treatment includes fasciectomy, needle fasciotomy, and enzymatic fasciectomy.
October 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29068929/effect-of-compound-21-a-selective-angiotensin-ii-type-2-receptor-agonist-in-a-murine-xenograft-model-of-dupuytren-disease
#3
Jessica Chisholm, Alison J Gareau, Stephanie Byun, Justin L Paletz, David Tang, Jason Williams, Terry LeVatte, Michael Bezuhly
BACKGROUND: Although surgical excision and intralesional collagenase injection are mainstays in Dupuytren disease treatment, no effective medical therapy exists for recurrent disease. Compound 21, a selective agonist of the angiotensin II type 2 receptor, has been shown to protect against fibrosis in models of myocardial infarction and stroke. The authors investigated the potential use of compound 21 in the treatment of Dupuytren disease. METHODS: Human dermal fibroblasts were treated in vitro with compound 21 and assessed for viability using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay, migration by means of scratch assay, and profibrotic gene transcription by means of quantitative reverse transcription polymerase chain reaction...
November 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29062633/comparative-effectiveness-of-needle-aponeurotomy-and-collagenase-injection-for-dupuytren-s-contracture-a-multicenter-study
#4
Chao Zhou, Steven E R Hovius, Adriana J Pieters, Harm P Slijper, Reinier Feitz, Ruud W Selles
BACKGROUND: Although the efficacy of collagenase clostridium histolyticum (CCH) injections has been demonstrated by randomized clinical trials, the relative effectiveness of CCH remains uncertain. Our aim was to compare the outcomes of CCH with those of percutaneous needle aponeurotomy (PNA) in daily clinical practice. METHODS: We analyzed data from patients undergoing PNA or CCH between 2011 and 2014 at 7 practice sites in the Netherlands. We examined the degree of improvement in contracture and adverse effects at 6-12 weeks after surgery or the last injection...
September 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28958137/short-term-effect-of-shockwave-therapy-temperature-controlled-high-energy-adjustable-multi-mode-emission-laser-or-stretching-in-dupuytren%C3%A2-s-disease-a-prospective-randomized-clinical-trial
#5
A Notarnicola, G Maccagnano, F Rifino, V Pesce, M F Gallone, I Covelli, B Moretti
Dupuytren’s disease is a debilitating disease of the hand characterized by nodules on the surface of the palm with progressive loss of finger extension. The chosen forms of treatment are infiltrative and surgical. Conservative treatment could be useful but few studies have been carried out and these regarded mainly stretching exercises and thermo-therapy. To date, no study has analyzed the effects of biostimulation with shock-waves (SW) and high energy laser therapy [Temperature controlled High Energy Adjustable multi-mode emission Laser (THEAL)]...
July 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28951096/variation-in-treatment-recommendations-for-dupuytren-disease
#6
Catherine McMillan, Celine Yeung, Paul Binhammer
PURPOSE: To examine agreement on Dupuytren disease (DD) treatment recommendations in an international sample of hand surgeons. METHODS: A survey was developed to determine expertise in needle aponeurotomy, surgery, and collagenase injection to treat DD and to examine treatment recommendations for 16 case scenarios. Case scenarios were predeveloped using expert input. Each case represented a unique combination of 4 dichotomous variables including cord thickness, contracture severity, patient age, and joint involvement...
September 23, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28917432/complications-after-treating-dupuytren-s-disease-a-systematic-literature-review
#7
C Krefter, M Marks, S Hensler, D B Herren, M Calcagni
The objective of this study was to review the incidence of complications associated with different treatment options for patients with Dupuytren's disease. In a systematic literature review, the PubMed, EMBASE, Cochrane and Scopus databases were searched for clinical studies reporting complications after collagenase treatment, percutaneous needle fasciotomy (PNF), fasciectomy and dermofasciectomy. The incidence of complications was extracted from each study and stratified by procedure. From a total of 2251 references, 113 studies were analyzed and included with complication incidences varying from 0% to 100%...
October 2017: Hand Surgery and Rehabilitation
https://www.readbyqxmd.com/read/28886342/a-genome-wide-association-study-of-dupuytren-disease-reveals-17-additional-variants-implicated-in-fibrosis
#8
Michael Ng, Dipti Thakkar, Lorraine Southam, Paul Werker, Roel Ophoff, Kerstin Becker, Michael Nothnagel, Andre Franke, Peter Nürnberg, Ana Isabel Espirito-Santo, David Izadi, Hans Christian Hennies, Jagdeep Nanchahal, Eleftheria Zeggini, Dominic Furniss
Individuals with Dupuytren disease (DD) are commonly seen by physicians and surgeons across multiple specialties. It is an increasingly common and disabling fibroproliferative disorder of the palmar fascia, which leads to flexion contractures of the digits, and is associated with other tissue-specific fibroses. DD affects between 5% and 25% of people of European descent and is the most common inherited disease of connective tissue. We undertook the largest GWAS to date in individuals with a surgically validated diagnosis of DD from the UK, with replication in British, Dutch, and German individuals...
September 7, 2017: American Journal of Human Genetics
https://www.readbyqxmd.com/read/28885215/hyperspectral-imaging-as-a-novel-diagnostic-tool-in-microcirculation-of-wounds
#9
Georg Daeschlein, Inga Langner, Thomas Wild, Sebastian von Podewils, Claudia Sicher, Thomas Kiefer, Michael Jünger
Monitoring of perfusion is a cornerstone in surgery, phlebology and basic science to proof wound healing by interventions. In chronic wound management it is of utmost importance to realize and parametrize wound bed perfusion to verify actual, and plan further treatment by noninvasive diagnostics. Up to now monitoring is based on visual inspection of wounds as conventionally practiced over more than decades. The main problems of visual inspection are the lack of standardization and comparability because of interindividual variations...
September 4, 2017: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/28871791/real-time-bioimpedance-sensing-of-antifibrotic-drug-action-in-primary-human-cells
#10
Maryam Parviz, Priyanka Toshniwal, Helena M Viola, Livia C Hool, P Mark W Fear, Fiona M Wood, Katharina Gaus, K Swaminathan Iyer, J Justin Gooding
Fibrotic diseases are among the most serious health issues with severe burdens due to their chronic nature and a large number of patients suffering from the debilitating effects and long-term sequelae. Collagenase treatment is a nonsurgical option but has limited results. To date, there is no potent noninvasive solution for fibrosis. Part of the reason for this is the lack of appropriate in vitro live cell screening tools to assess the efficacy of new therapeutical agents. Here, we demonstrate the utility of a cell-based electrochemical impedance biosensor platform to screen the efficacy of potential antifibrotic compounds...
October 27, 2017: ACS Sensors
https://www.readbyqxmd.com/read/28860097/effectiveness-of-conservative-surgical-and-post-surgical-interventions-for-trigger-finger-dupuytren-s-disease-and-de-quervain-s-disease-a-systematic-review
#11
REVIEW
Bionka M Huisstede, Saskia Gladdines, Manon S Randsdorp, Bart W Koes
OBJECTIVES: To provide an evidence-based overview of the effectiveness of conservative and (post)-surgical interventions for trigger finger, Dupuytren's -, and De Quervain's disease. DATA SOURCES: The Cochrane Library, PEDro, PubMed, Embase and CINAHL were searched to identify relevant systematic reviews and RCTs. DATA SELECTION AND EXTRACTION: Two reviewers independently extracted the data, and assessed the methodological quality. DATA SYNTHESIS: A best-evidence synthesis was performed to summarize the results...
August 28, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28854973/efficacy-and-safety-of-collagenase-clostridium-histolyticum-for-dupuytren-disease-nodules-a-randomized-controlled-trial
#12
Bronier Costas, Stephen Coleman, Greg Kaufman, Robert James, Brian Cohen, R Glenn Gaston
BACKGROUND: To determine the safety and efficacy of collagenase clostridium histolyticum (CCH) injection for the treatment of palmar Dupuytren disease nodules. METHODS: In this 8-week, double-blind trial, palpable palmar nodules on one hand of adults with Dupuytren disease were selected for treatment. Patients were randomly assigned using an interactive web response system to receive a dose of 0.25 mg, 0.40 mg, or 0.60 mg (1:1:1 ratio) and then allocated to active treatment (CCH) or placebo (4:1 ratio)...
August 30, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28843342/readability-of-online-materials-for-dupuytren-s-contracture
#13
Pauline Joy F Santos, David A Daar, Austin Badeau, Amber Leis
STUDY DESIGN: Descriptive. BACKGROUND: Dupuytren's contracture is a common disorder involving fibrosis of the palmar fascia. As patients are increasingly using online materials to gather health care information, it is imperative to assess the readability and appropriateness of this content. The recommended grade level for patient educational materials is seventh to eighth grade according to the National Institutes of Health. This study aims to assess the readability and content of online patient resources for Dupuytren's contracture...
August 23, 2017: Journal of Hand Therapy: Official Journal of the American Society of Hand Therapists
https://www.readbyqxmd.com/read/28841903/a-feasibility-study-investigating-the-acceptability-and-design-of-a-multicentre-randomised-controlled-trial-of-needle-fasciotomy-versus-limited-fasciectomy-for-the-treatment-of-dupuytren-s-contractures-of-the-fingers-hand-1-study-protocol-for-a-randomised-controlled
#14
Eleanor Harrison, Wei Tan, Nicola Mills, Alexia Karantana, Kirsty Sprange, Lelia Duley, Daisy Elliott, Jane Blazeby, William Hollingworth, Alan A Montgomery, Tim Davis
BACKGROUND: Dupuytren's contractures are fibrous cords under the skin of the palm of the hand. The contractures are painless but cause one or more fingers to curl into the palm, resulting in loss of function. Standard treatment within the NHS is surgery to remove (fasciectomy) or divide (fasciotomy) the contractures, and the treatment offered is frequently determined by surgeon preference. This study aims to determine the feasibility of conducting a large, multicentre randomised controlled trial to assess the clinical and cost-effectiveness of needle fasciotomy versus limited fasciectomy for the treatment of Dupuytren's contracture...
August 25, 2017: Trials
https://www.readbyqxmd.com/read/28841617/benefit-of-local-anesthesia-in-reducing-pain-during-collagenase-injection-for-dupuytren-s-contracture
#15
Jesper Nordenskjöld, Markus Waldén, Anders Kjellin, Herbert Franzén, Isam Atroshi
Collagenase injection for Dupuytren's contracture is commonly administered without anesthesia. The authors studied the benefit of injecting local anesthesia before collagenase in reducing treatment-related pain. This prospective cohort study included 187 patients (mean age, 69 years; 80 percent men) at two orthopedic departments in Sweden. At one center, 161 consecutive patients scheduled for collagenase injection were assigned to two groups by alternating outpatient clinics; 78 received collagenase without local anesthesia using a modified method (injecting 0...
September 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28806826/-treatment-of-dupuytren-s-disease-with-collagenase-injections-in-germany-efficacy-and-adverse-effects-in-110-treated-joints
#16
Adrian Pototschnig, Elias Volkmer, Riccardo E Giunta
Background Since 2011, a new minimally-invasive treatment for Dupuytren's disease has been available in the form of injectable collagenase (Xiapex®, Pfizer). Purpose Our aim is to report about the results and adverse effects of injectable collagenase for the treatment of Dupuytren's disease in Germany. Patients and Methods We treated 78 patients (61 male, 17 female) with 87 injections in 87 digits (little finger n = 40, ring finger n = 37, middle finger n = 8 and index n = 2). We documented the range of motion before treatment, after 6 weeks and after 6 months...
August 2017: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://www.readbyqxmd.com/read/28774258/the-hand-of-sabazios-evidence-of-dupuytren-s-disease-in-antiquity-and-the-origin-of-the-hand-of-benediction
#17
Matthew J Zdilla
Dupuytren's disease gained its eponym from the surgeon Baron Guillaume Dupuytren (1777-1835). However, the terms "Cline's contracture" and "Cooper's contracture," named after the two surgeons who proposed the treatment for the palmar contractures prior to Dupuytren, have also been used to describe the disease. In addition to the eponyms attributed to these three surgeons, a number of other appellations with interesting provenance exist for Dupuytren's disease including the "Curse of the MacCrimmons," "Celtic hand," "Viking's disease," and the "Hand of Benediction...
September 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/28732844/efficacy-and-safety-of-collagenase-treatment-for-dupuytren-s-disease-2-year-follow-up-results
#18
A Van Beeck, M Van den Broek, M Michielsen, K Didden, K Vuylsteke, F Verstreken
Dupuytren's contracture is a common hand problem that affects the palmar fascia. Several treatment options exist, but none are curative and recurrence is common. Bacterial collagenase has recently been proven beneficial for treating Dupuytren's disease, cleaving the collagen fibers at different sites, with weakening and eventually rupture of the fibrous cords after manipulation. An independent prospective follow-up study was organized on 87 patients, treated with one or more collagenase injections. Inclusion criteria were a contracture of at least 20° at the metacarpophalangeal (MCP) or the proximal interphalangeal (PIP) joint...
October 2017: Hand Surgery and Rehabilitation
https://www.readbyqxmd.com/read/28732843/preliminary-results-with-non-centrifuged-autologous-fat-graft-and-percutaneous-aponeurotomy-for-treating-dupuytren-s-disease
#19
U Tuncel, A Kurt, M Gumus, O Aydogdu, N Güzel, O Demir
The aim of this study was to describe our experience with treating Dupuytren's disease using needle aponeurotomy and non-centrifuged autologous fat grafting. The study included 17 patients (18 hands). Patients were treated with needle aponeurotomy and non-centrifuged autologous fat graft under general anesthesia. The fat grafts were injected into the surgical area so as to stay in contact with the operated site. An extension splint was used for 1 week postoperatively and the patients received hand therapy for 3 weeks...
October 2017: Hand Surgery and Rehabilitation
https://www.readbyqxmd.com/read/28691512/the-incidence-of-complex-regional-pain-syndrome-in-simultaneous-surgical-treatment-of-carpal-tunnel-syndrome-and-dupuytren-contracture
#20
Mitchell Buller, Steven Schulz, Morton Kasdan, Bradon J Wilhelmi
BACKGROUND: To determine the incidence of complex regional pain syndrome (CRPS) in the concurrent surgical treatment of Dupuytren contracture (DC) and carpal tunnel syndrome (CTS) through a thorough review of evidence available in the literature. METHODS: The indices of 260 hand surgery books and PubMed were searched for concomitant references to DC and CTS. Studies were eligible for inclusion if they evaluated the outcome of patients treated with simultaneous fasciectomy or fasciotomy for DC and carpal tunnel release using CRPS as a complication of treatment...
July 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
keyword
keyword
85697
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"