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Atopic eczema

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https://www.readbyqxmd.com/read/27928524/review-of-medicinal-remedies-on-hand-eczema-based-on-iranian-traditional-medicine-a-narrative-review-article
#1
REVIEW
Parvin Mansouri, Aleme Khademi, Daryoush Pahlevan, Zahra Memariani, Jale Aliasl, Laila Shirbeigii
BACKGROUND: Hand Eczema (HE) is a dermatological disorder with frequent relapses and multiple causes such as atopic, allergic and irritant contact dermatitis. The management is complex because of the wide range of different pathogenesis. Efficacy of some of available treatments is not well established and it can affect patients' quality of life significantly. METHODS: Reports on HE such as diagnosis, pathophysiology, pharmacological and nonpharmacological therapy that described in medieval Iranian medicine, were gathered and analyzed from selected medical and pharmaceutical textbooks of Iranian Traditional Medicine (ITM)...
August 2016: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/27918470/vitamin-d-status-and-efficacy-of-vitamin-d-supplementation-in-atopic-dermatitis-a-systematic-review-and-meta-analysis
#2
Min Jung Kim, Soo-Nyung Kim, Yang Won Lee, Yong Beom Choe, Kyu Joong Ahn
Recent literature has highlighted the possible role of vitamin D in atopic dermatitis (AD), and that vitamin D supplementation might help to treat AD. This study determined the relationship between vitamin D level and AD, and assessed the efficacy of vitamin D supplementation. We searched the MEDLINE, EMBASE, and Cochrane databases up to May 2015. Observational studies and randomized controlled trials were included based on the available data on the serum 25-hydroxyvitamin D (25(OH)D) level and quantified data available for severity assessed using the Scoring Atopic Dermatitis (SCORAD) index or Eczema Area and Severity Index (EASI) score...
December 3, 2016: Nutrients
https://www.readbyqxmd.com/read/27910751/recent-advances-in-pharmacotherapeutic-paradigm-of-mild-to-recalcitrant-atopic-dermatitis
#3
Zahid Hussain, Shariza Sahudin, Hnin Ei Thu, Ahmad Nazrun Shuid, Syed Nasir Abbas Bukhari, Endang Kumolosasi
Atopic dermatitis (AD) is a common, chronic skin inflammatory disorder characterized by perivascular infiltration of immunoglobulin E (IgE), T lymphocytes, and mast cells. The key factors responsible for the pathophysiology of this disease are immunological disorders and defects in epidermal barrier properties. Pruritus, intense itching, psychological stress, deprived physical and mental performance, and sleep disturbance are the hallmark features of this dermatological disorder. Preventive interventions such as educational programs, avoidance of allergens, and exclusive care toward the skin could play a partial role in suppressing the symptoms...
2016: Critical Reviews in Therapeutic Drug Carrier Systems
https://www.readbyqxmd.com/read/27904267/application-of-topical-acids-improves-atopic-dermatitis-in-murine-model-by-enhancement-of-skin-barrier-functions-regardless-of-the-origin-of-acids
#4
Noo Ri Lee, Hae-Jin Lee, Na Young Yoon, Donghye Kim, Minyoung Jung, Eung Ho Choi
BACKGROUND: The acidic pH of the stratum corneum (SC) is important for epidermal permeability barrier homeostasis. Acidification of the skin surface has been suggested as a therapeutic strategy for skin disorders such as atopic dermatitis (AD). OBJECTIVE: We performed an animal study to evaluate the usefulness of acidification of SC for inhibition of AD lesions and to find out if the therapeutic effect of vinegar is attributable to its herbal contents, rather than its acidity...
December 2016: Annals of Dermatology
https://www.readbyqxmd.com/read/27904184/current-understanding-in-pathogenesis-of-atopic-dermatitis
#5
Tess McPherson
There have been advances in our understanding of the complex pathogenesis of atopic eczema over the past few decades. This article examines the multiple factors which are implicated in this process.
November 2016: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/27902816/association-of-filaggrin-loss-of-function-and-thymic-stromal-lymphopoietin-variation-with-treatment-use-in-pediatric-atopic-dermatitis
#6
Joshua Chang, Nandita Mitra, Ole Hoffstad, David J Margolis
Importance: Atopic dermatitis (AD) is a common illness of childhood. Objective: To determine whether variations in FLG and TSLP genotype corresponded to differences in treatment use over time. Design, Setting, and Participants: This prospective cohort study recruited and followed a volunteer sample of 842 children enrolled in the Pediatric Eczema Elective Registry who provided saliva samples for DNA extraction for 10 years. Eligibility criteria included age 2 to 17 years, AD diagnosis without cancer, and prior pimecrolimus use...
November 30, 2016: JAMA Dermatology
https://www.readbyqxmd.com/read/27888035/racial-differences-in-food-allergy-phenotype-and-health-care-utilization-among-us-children
#7
Mahboobeh Mahdavinia, Susan R Fox, Bridget M Smith, Christine James, Erica L Palmisano, Aisha Mohamed, Zeeshan Zahid, Amal H Assa'ad, Mary C Tobin, Ruchi S Gupta
BACKGROUND: Food allergy (FA) is a prevalent condition in the United States, but little is known about its phenotypes in racial minority groups. OBJECTIVE: The objective of this study was to characterize disease phenotypes and disparities in health care utilization among African American (AA), Hispanic, and white children with FA. METHODS: We conducted a large, 2-center, retrospective cohort study of children aged 0-17 years with FA seen in allergy/immunology clinics at 2 urban tertiary care centers in the United States...
November 22, 2016: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/27881942/allergic-rhinitis-bronchial-asthma-and-other-allergies-in-patients-with-alzheimer-s-disease-unnoticed-issue
#8
Andrzej Bożek, Piotr Bednarski, Jerzy Jarzab
INTRODUCTION: Allergic diseases are becoming more prevalent in elderly patients. Allergic diseases have been observed in patients with Alzheimer's disease (AD). The prevalence of atopic bronchial asthma, allergic rhinitis and atopic dermatitis was analyzed in such elderly Polish population. AIM: Analysis of the presence of allergic diseases in the patients with AD in Poland, including asthma, allergic rhinoconjunctivitis and atopic dermatitis. MATERIAL AND METHODS: The recruitment of subjects with AD was conducted at 6 sites representative of Polish rural and urban areas, and 1060 subjects with a mean age of 69...
October 2016: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/27881529/co-occurrence-and-clustering-of-health-conditions-at-age-11-cross-sectional-findings-from-the-millennium-cohort-study
#9
Kathryn R Hesketh, James Fagg, Graciela Muniz-Terrera, Helen Bedford, Catherine Law, Steven Hope
OBJECTIVES: To identify patterns of co-occurrence and clustering of 6 common adverse health conditions in 11-year-old children and explore differences by sociodemographic factors. DESIGN: Nationally representative prospective cohort study. SETTING: Children born in the UK between 2000 and 2002. PARTICIPANTS: 11 399 11-year-old singleton children for whom data on all 6 health conditions and sociodemographic information were available (complete cases)...
November 22, 2016: BMJ Open
https://www.readbyqxmd.com/read/27868221/what-s-new-in-atopic-eczema-an-analysis-of-systematic-reviews-published-in-2014-part-2-treatment-and-prevention
#10
REVIEW
A Lloyd-Lavery, N K Rogers, S J Hatfield, D Grindlay, R Barnett, K S Thomas
This review forms part of a series of annual updates that summarize the evidence base for atopic eczema (AE). It provides a summary of key findings from 12 systematic reviews (SRs) that were published or indexed during 2014, and focuses on the treatment and prevention of AE. For an update of SRs on the epidemiology, mechanisms of disease and methodological issues, see Part 1 of this update. Although phototherapy and various systemic medications (including ciclosporin, azathioprine and methotrexate) are commonly used to treat AE, many of these have not been robustly assessed in head-to-head randomized controlled trials...
November 21, 2016: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/27858989/poem-a-core-instrument-to-measure-symptoms-in-clinical-trials-a-home-statement
#11
Ph I Spuls, L A A Gerbens, E Simpson, C J Apfelbacher, J R Chalmers, K S Thomas, C A C Prinsen, L B von Kobyletzki, J A Singh, H C Williams, J Schmitt
BACKGROUND: The Harmonising Outcome Measures for Eczema (HOME) initiative has defined four core outcome domains for a core outcome set (COS) to be measured in all atopic eczema (AE) trials to ensure cross-trial comparison: clinical signs, symptoms, quality of life and long-term control. OBJECTIVES: The aim of this paper is to report on the consensus process that was used to select the core instrument to consistently assess symptoms in all future AE trials. METHODS: Following the HOME roadmap, two systematic reviews were performed which identified three instruments that had sufficient evidence of validity, reliability, and feasibility to be considered for the final COS...
November 17, 2016: British Journal of Dermatology
https://www.readbyqxmd.com/read/27846960/prescribing-success-developing-an-integrated-prescription-and-eczema-action-plan-for-atopic-dermatitis
#12
EDITORIAL
Maxwell B Sauder, Alana McEvoy, Michele Louise Ramien
No abstract text is available yet for this article.
December 2016: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/27845865/gastrodia-elata-blume-extract-modulates-antioxidant-activity-and-ultraviolet-a-irradiated-skin-aging-in-human-dermal-fibroblast-cells
#13
Eunju Song, Haeyon Chung, Eugene Shim, Jung-Ky Jeong, Bok-Kyung Han, Hyuk-Joon Choi, Jinah Hwang
Gastrodia elata Blume (GEB), a traditional herbal medicine, has been used to treat a wide range of neurological disorders (e.g., paralysis and stroke) and skin problems (e.g., atopic dermatitis and eczema) in oriental medicine. This study was designed to investigate the antioxidant ability of GEB and its antiaging effect on human dermal fibroblast cells (HDF). The total phenolic and flavonoid contents of GEB were 21.8 and 0.43 mg/g dry weight (DW), respectively. The ergothioneine content of GEB was 0.41 mg/mL DW...
November 2016: Journal of Medicinal Food
https://www.readbyqxmd.com/read/27832218/guidelines-for-the-management-of-atopic-dermatitis-in-singapore
#14
Yong Kwang Tay, Yuin Chew Chan, Nisha Suyien Chandran, Madeline Sl Ho, Mark Ja Koh, Yen Loo Lim, Mark By Tang, Thamotharampillai Thirumoorthy
INTRODUCTION: Atopic dermatitis is a common, chronic pruritic condition affecting both children and adults, which has a negative impact on the quality of life. These guidelines were developed by an expert workgroup appointed by the Dermatological Society of Singapore, to provide doctors with information to assist in the management of their patients with atopic dermatitis. The workgroup members are experienced dermatologists with interest and expertise in eczemas. MATERIALS AND METHODS: Workgroup members arrived at a consensus on the topics to be included...
October 2016: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/27828633/staphylococcus-aureus-resistance-to-topical-antimicrobials-in-atopic-dermatitis
#15
Giancarlo Rezende Bessa, Vanessa Petry Quinto, Daiane Corrêa Machado, Caroline Lipnharski, Magda Blessmann Weber, Renan Rangel Bonamigo, Pedro Alves D'Azevedo
Background: Topical antimicrobial drugs are indicated for limited superficial pyodermitis treatment, although they are largely used as self-prescribed medication for a variety of inflammatory dermatoses, including atopic dermatitis. Monitoring bacterial susceptibility to these drugs is difficult, given the paucity of laboratory standardization. Objective: To evaluate the prevalence of Staphylococcus aureus topical antimicrobial drug resistance in atopic dermatitis patients...
September 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/27822435/isolated-ectopic-cilia-in-an-11-year-old-girl
#16
Hosny Ahmed Zein, M Tarek A Moustafa
Ectopic cilia (EC) are a very rare condition with only few cases reported in literature. Many associations were seen with ectopic cilia which include distichiasis, choristoma and aberrant lacrimal gland, hypochromic nevus, atopic eczema and others. We are reporting a case of an 11-year-old girl with isolated left upper lid ectopic cilia, which was confirmed by surgical removal and histopathological study.
2016: GMS Ophthalmology Cases
https://www.readbyqxmd.com/read/27813070/atopic-dermatitis-a-tale-of-two-distinct-pathomechanisms-that-make-you-itch
#17
Edward F Knol, DirkJan Hijnen
Atopic dermatitis (AD) or eczema is the most common chronic inflammatory skin disease. It is a multifactorial disease with local and systemic immune changes. Current therapies focus on restoring the local skin barrier or inhibiting immune responses. In this issue of the European Journal of Immunology, Sehra et al. [Eur. J. Immunol. 2016. 46:2609-2613] describe a mouse model with T-cell-specific expression of constitutively active Stat6 in Flaky tail mice, which have mutations in the Flg and Tmem79 genes. The authors describe that it is the combination of changes in the skin barrier proteins filaggrin and Tmem79, together with Th2 cytokine signaling in the constitutively active Stat6 transgene, that drives the immune-pathomechanism in AD...
November 2016: European Journal of Immunology
https://www.readbyqxmd.com/read/27812754/household-environment-lifestyle-behaviors-and-dietary-habits-in-relation-to-childhood-atopic-eczema-in-shanghai-china
#18
Jiao Cai, Wei Liu, Yu Hu, Zhijun Zou, Li Shen, Chen Huang
PURPOSES: We aim to investigate associations of the child's individual characteristics, building characteristics, home environmental exposures, family lifestyle behaviors, and dietary habits on childhood eczema during lifetime-ever and in the last year before the survey. METHODS: During April 2011-April 2012, we conducted a cross-sectional study and collected 13,335 parents-reported questionnaires of 4-6-year-old children from 72 kindergartens in Shanghai, China...
November 3, 2016: International Archives of Occupational and Environmental Health
https://www.readbyqxmd.com/read/27812181/altered-gut-microbiota-composition-associated-with-eczema-in-infants
#19
Huajun Zheng, Hong Liang, Yuezhu Wang, Maohua Miao, Tao Shi, Fen Yang, Enuo Liu, Wei Yuan, Zai-Si Ji, De-Kun Li
Eczema is frequently the first manifestation of an atopic diathesis and alteration in the diversity of gut microbiota has been reported in infants with eczema. To identify specific bacterial communities associated with eczema, we conducted a case-control study of 50 infants with eczema (cases) and 51 healthy infants (controls). We performed high-throughput sequencing for V3-V4 hypervariable regions of the 16S rRNA genes from the gut fecal material. A total of 12,386 OTUs (operational taxonomic units) at a 97% similarity level were obtained from the two groups, and we observed a difference in taxa abundance, but not the taxonomic composition, of gut microbiota between the two groups...
2016: PloS One
https://www.readbyqxmd.com/read/27805275/what-s-new-in-atopic-eczema-an-analysis-of-systematic-reviews-published-in-2014-part-1-epidemiology-risk-factors-and-outcomes
#20
REVIEW
S J Hatfield, N K Rogers, A Lloyd-Lavery, D Grindlay, R Barnett, K S Thomas
This review summarizes key findings from nine systematic reviews on atopic eczema (AE) published or first indexed in 2014. It focuses on epidemiology, disease processes and methodological issues. There is reasonable evidence to conclude that high birth weight (> 4000 g) is a risk factor for the development of AE. A lower socioeconomic position is associated with lower prevalence of AE. The effect of exposure to traffic-related air pollution in childhood on the development of AE is uncertain. CD14 polymorphisms do not appear to have an effect in AE...
November 2, 2016: Clinical and Experimental Dermatology
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