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https://www.readbyqxmd.com/read/28932371/estimating-postoperative-survival-rate-of-gastric-cancer-patients-and-its-effective-factors-in-babol-northern-iran-2006-2011
#1
Seyed-Reza Modarres, Abdolrahim Gholizadeh-Pasha, Soheil Khatibi, Sepideh Siadati
BACKGROUND: The importance of gastric cancer, considering its progressive course and high mortality is one of the reasons we pay attention to patients' survival and the significance of this study was to estimate survival and determine the effective factors on patients with gastric cancer. METHODS: In this cross-sectional study, all patients with gastric cancer who underwent surgery in Shahid Beheshti Hospital, Babol, northern Iran during 2006-2011 were enrolled...
2017: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/28932365/causal-role-of-infectious-agents-in-cancer-an-overview
#2
REVIEW
Jila Masrour-Roudsari, Soheil Ebrahimpour
Cancer is a complex group of diseases with multiple eventual causes. The underlying causes are not fully known. Thus, learning more about the known causes of cancer is an important issue. Moreover, among these factors, infection and its association to cancers is controversial. Although, it seems that the genome instability of the cells can initiate cancer development. The purpose of this review was to present the role of infection in the development of cancer. Infectious agents, such as hepatitis B (HBV) and C viruses (HCV), Epstein-Barr virus (EBV), human papillomavirus (HPV), human immunodeficiency virus type 1 (HIV-1), Helicobacter pylori (H...
2017: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/28906323/novel-method-enabling-the-use-of-cryopreserved-primary-acute-myeloid-leukemia-cells-in-functional-drug-screens
#3
Michelle Degnin, Anupriya Agarwal, Katherine Tarlock, Soheil Meshinchi, Brian J Druker, Cristina E Tognon
The ability to assess antileukemic drug activity on primary patient samples is a powerful tool in determining potential drug targets and selection of therapeutic agents with biological and functional rationale. We previously established small molecule inhibitor screens for use on freshly isolated leukemia cells for this purpose. Here we describe a method that produces functional small molecule inhibitor screening results using cryopreserved primary acute myeloid leukemia cells. This method was established to take advantage of biorepositories containing archival material, such as those established by the Children's Oncology Group, and to enable validation of potential pathway dependencies uncovered by genomic analysis...
September 12, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28899746/performance-of-five-research-domain-automated-wm-lesion-segmentation-methods-in-a-multi-center-ms-study
#4
Alexandra de Sitter, Martijn D Steenwijk, Aurélie Ruet, Adriaan Versteeg, Yahou Liu, Ronald A van Schijndel, Petra J W Pouwels, Iris D Kilsdonk, Keith S Cover, Bob W van Dijk, Stefan Ropele, Maria A Rocca, Marios Yiannakas, Mike P Wattjes, Soheil Damangir, Giovanni B Frisoni, Jaume Sastre-Garriga, Alex Rovira, Christian Enzinger, Massimo Filippi, Jette Frederiksen, Olga Ciccarelli, Ludwig Kappos, Frederik Barkhof, Hugo Vrenken
BACKGROUND AND PURPOSE: In vivoidentification of white matter lesions plays a key-role in evaluation of patients with multiple sclerosis (MS). Automated lesion segmentation methods have been developed to substitute manual outlining, but evidence of their performance in multi-center investigations is lacking. In this work, five research-domain automated segmentation methods were evaluated using a multi-center MS dataset. METHODS: 70 MS patients (median EDSS of 2...
September 9, 2017: NeuroImage
https://www.readbyqxmd.com/read/28891835/the-effect-of-dextromethorphan-premedication-on-cough-and-patient-tolerance-during-flexible-bronchoscopy-a-randomized-double-blind-placebo-controlled-trial
#5
Shahideh Amini, Soheil Peiman, Mahdi Khatuni, Marziyeh Ghalamkari, Besharat Rahimi
BACKGROUND: Patients undergoing bronchoscopy can experience problems such as anxiety and cough, requiring various doses of sedatives and analgesics. The purposes of this study were to investigate the effect of premedication with dextromethorphan on patients' cough and anxiety, and the use of analgesics/sedatives during flexible bronchoscopy (FB). METHODS: A randomized, double-blind, placebo-controlled, prospective study was performed to assess the effect of dextromethorphan premedication on patients who underwent diagnostic bronchoscopy...
September 7, 2017: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/28883080/phenotype-in-combination-with-genotype-improves-outcome-prediction-in-acute-myeloid-leukemia-a-report-from-children-s-oncology-group-protocol-aaml0531
#6
Andrew P Voigt, Lisa Eidenschink Brodersen, Todd A Alonzo, Robert B Gerbing, Andrew J Menssen, Elisabeth R Wilson, Samir Kahwash, Susana C Raimondi, Betsy A Hirsch, Alan S Gamis, Soheil Meshinchi, Denise A Wells, Michael R Loken
Diagnostic biomarkers can be used to determine relapse risk in acute myeloid leukemia, and certain genetic aberrancies have prognostic relevance. A diagnostic immunophenotypic expression profile, which quantifies the amounts of distinct gene products, not just their presence or absence, was established to improve outcome prediction for patients with acute myeloid leukemia. The immunophenotypic expression profile, which defines each patient's leukemia as a location in 15-dimensional space, was generated for 769 patients enrolled in the Children's Oncology Group AAML0531 protocol...
September 7, 2017: Haematologica
https://www.readbyqxmd.com/read/28846013/feasibility-and-data-quality-of-the-national-spinal-cord-injury-registry-of-iran-nscir-ir-a-pilot-study
#7
Khatereh Naghdi, Zahra Azadmanjir, Soheil Saadat, Aidin Abedi, Sahar Koohi Habibi, Pegah Derakhshan, Mahdi Safdarian, Shayan Abdollah Zadegan, Abbas Amirjamshidi, Mahdi Sharif-Alhoseini, Jalil Arab Kheradmand, Mahdi Mohammadzadeh, Kazem Zendehdel, Zahra Khazaeipour, Seyed Mahmood Ramak Hashemi, Hooshang Saberi, Kourosh Karimi Yarandi, Seyed Ebrahim Ketabchi, Shahrokh Yousefzadeh-Chabok, Hamid Heidari, Arezo Sotodeh, Khalil Pestei, Zahra Ghodsi, Farideh Sadeghian, Vanessa Noonan, Edward C Benzel, Gerard Oreilly, Jens Chapman, Ellen Merete Hagen, Michael G Fehlings, Alexander R Vaccaro, Morteza Faghih Jooybari, Mohammad Reza Zarei, Mohammad Reza Zafarghandi, Payman Salamati, Saeed Nezareh, Moein Khormali, Mohsen Sadeghi-Naini, Seyed Behzad Jazayeri, Bizhan Aarabi, Vafa Rahimi-Movaghar
BACKGROUND: Spinal cord injury (SCI) is one of the most disabling consequences of trauma with unparalleled economic, social, and personal burden. Any attempt aimed at improving quality of care should be based on comprehensive and reliable data. This pilot investigation studied the feasibility of implementing the National Spinal Cord and Column Injury Registry of Iran (NSCIR-IR) and scrutinized the quality of the registered data. METHODS: From October 2015 to May 2016, over an 8-month period, 65 eligible trauma patients who were admitted to hospitals in three academic centers in mainland Iran were included in this pilot study...
August 2017: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/28836761/high-speed-4d-computational-microscopy-of-bacterial-surface-motility
#8
Jaime de Anda, Ernest Y Lee, Calvin K Lee, Rachel R Bennett, Xiang Ji, Soheil Soltani, Mark C Harrison, Amy E Baker, Yun Luo, Tom Chou, George A O'Toole, Andrea M Armani, Ramin Golestanian, Gerard C L Wong
Bacteria exhibit surface motility modes that play pivotal roles in early-stage biofilm community development, such as type IV pili-driven "twitching" motility and flagellum-driven "spinning" and "swarming" motility. Appendage-driven motility is controlled by molecular motors, and analysis of surface motility behavior is complicated by its inherently 3D nature, the speed of which is too fast for confocal microscopy to capture. Here, we combine electromagnetic field computation and statistical image analysis to generate 3D movies close to a surface at 5 ms time resolution using conventional inverted microscopes...
September 1, 2017: ACS Nano
https://www.readbyqxmd.com/read/28827021/toward-cure-chronic-hepatitis-b-infection-and-hepatocellular-carcinoma-prevention-lessons-learned-from-nucleos-t-ide-analogues-therapy
#9
REVIEW
Soheil Tavakolpour, Hajar Sadat Mirsafaei, Somayeh Elkaei Behjati, Mojtaba Ghasemiadl, Meisam Akhlaghdoust, Shahnaz Sali
Nucleos(t)ide analogues (NAs) could successfully suppress hepatitis B virus (HBV) replication in patients with chronic hepatitis B (CHB). However, due to probable development of drug resistance or low/delayed response, these treatments may not be satisfactory. In addition to the HBV DNA polymerase inhibiting activity, these drugs could lead to changes in cytokines profiles. It is important to monitor these changes so that they could be used as target of treatment. Evaluating the previously reported immune responses due to NAs treatments, it was concluded that interferon-gamma (IFN-γ), tumor necrosis factor-alpha (TNF-α), interleukin-4 (IL-4), and IL-12 increase after the treatment...
August 5, 2017: Immunology Letters
https://www.readbyqxmd.com/read/28814098/quantitative-and-qualitative-mri-evaluation-of-cerebral-small-vessel-disease-in-an-elderly-population-a-longitudinal-study
#10
Ruta Nylander, Markus Fahlström, Egill Rostrup, Joel Kullberg, Soheil Damangir, Håkan Ahlström, Lars Lind, Elna-Marie Larsson
Background Cerebral white matter hyperintensities (WMHs), lacunes, and microbleeds are seen on magnetic resonance imaging (MRI) in small vessel disease (SVD). Purpose To assess SVD on MRI and its evolution over five years in an elderly population and to investigate whether relative cerebral blood flow (rCBF) at baseline was related to the progression of white matter (WM) lesions. Material and Methods In a population-based study, 406 participants aged 75 years underwent morphological MRI of the brain and 252 of them again at age 80 years...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28797806/towards-personalized-medicine-for-patients-with-autoimmune-diseases-opportunities-and-challenges
#11
REVIEW
Soheil Tavakolpour
There is generally no cure for autoimmune disorders, but the symptoms can be managed. Currently available drugs/treatments are more potent than those in the past decades. However, finding the right drug and right patients has remained a serious problem. We should revise our diagnosis criteria to more accurate ones. During the recent years, personalized medicine has attracted much attention. However, it needs to be well-explained for autoimmune diseases. Personalized medicine aims to find the most optimum drugs for a patient...
August 8, 2017: Immunology Letters
https://www.readbyqxmd.com/read/28796968/measure-for-measure-measuring-the-impact-of-measuring-residual-disease-in-acute-myeloid-leukemia
#12
Frederick R Appelbaum, Soheil Meshinchi
No abstract text is available yet for this article.
August 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28769726/a-new-species-of-the-genus-capoeta-valenciennes-1842-from-the-caspian-sea-basin-in-iran-teleostei-cyprinidae
#13
Arash Jouladeh-Roudbar, Soheil Eagderi, Hamid Reza Ghanavi, Ignacio Doadrio
A new species of algae-scraping cyprinid of the genus Capoeta Valenciennes, 1842 is described from the Kheyroud River, located in the southern part of the Caspian Sea basin in Iran. The species differs from other members of this genus by a combination of the following characters: one pair of barbels; predorsal length equal to postdorsal length; maxillary barbel slightly smaller than eye's horizontal diameter and reach to posterior margin of orbit; intranasal length slightly shorter than snout length; lateral line with 46-54 scales; 7-9 scales between dorsal-fin origin and lateral line, and 6-7 scales between anal-fin origin and lateral line...
2017: ZooKeys
https://www.readbyqxmd.com/read/28767288/arsenic-trioxide-consolidation-allows-anthracycline-dose-reduction-for-pediatric-patients-with-acute-promyelocytic-leukemia-report-from-the-children-s-oncology-group-phase-iii-historically-controlled-trial-aaml0631
#14
MULTICENTER STUDY
Matthew A Kutny, Todd A Alonzo, Robert B Gerbing, Yi-Cheng Wang, Susana C Raimondi, Betsy A Hirsch, Cecilia H Fu, Soheil Meshinchi, Alan S Gamis, James H Feusner, John J Gregory
Purpose The Children's Oncology Group AAML0631 trial for newly diagnosed pediatric acute promyelocytic leukemia (APL) was a phase III historically controlled trial to determine the survival of patients receiving arsenic trioxide (ATO) consolidation and reduced doses of anthracyclines. Patients and Methods Patients age 2 to 21 years with de novo APL confirmed by PML-RARα polymerase chain reaction were stratified as standard risk (SR) or high risk (HR) on the basis of diagnostic WBC count. All patients received all-trans retinoic acid (ATRA) during induction, each consolidation course, and maintenance...
September 10, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28759290/high-dose-vitamin-d-supplementation-is-associated-with-a-reduction-in-depression-score-among-adolescent-girls-a-nine-week-follow-up-study
#15
Afsane Bahrami, Seyed Reza Mazloum, Shahrokh Maghsoudi, Davood Soleimani, Sayyed Saeid Khayyatzadeh, Soheil Arekhi, Arsalan Arya, Seyed Jamal Mirmoosavi, Gordon A Ferns, Hamidreza Bahrami-Taghanaki, Majid Ghayour-Mobarhan
Although vitamin D deficiency is known to be a risk factor for some psychological disorders, there have been few studies on the effects of vitamin D supplementation on their symptoms. Depression and aggression are common mental disorders and are associated with disability and disease burden. We aimed to evaluate the effectiveness of high-dose vitamin D supplementation on depression and aggression scores in adolescent girls. Nine hundred forty adolescent girls received vitamin D3 at a dose of 50,000 IU/week for 9 weeks...
July 31, 2017: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/28756466/anatomic-and-non-anatomic-anterior-cruciate-ligament-posterolateral-bundle-augmentation-affects-graft-function
#16
Can Yapici, Levent Surer, Kenan Keklikci, Dongliang Shi, Soheil Sabzevari, Monica A Linde, Patrick Smolinski, Freddie H Fu
PURPOSE: The purpose of this study is to compare knee laxity and graft function (tissue force) between anatomic and non-anatomic posterolateral (PL) bundle augmentation. METHODS: Twelve (n = 12) fresh-frozen mature, unpaired porcine knees were tested using a robotic testing system. Four knee states were compared: (a) intact anterior cruciate ligament (ACL), (b) deficient PL and intermediate bundles, (c) anatomic PL augmentation, and (d) non-anatomic PL augmentation...
July 29, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28748052/the-effect-of-repeated-torque-tightening-on-total-lengths-of-implant-abutments-in-different-internal-implant%C3%A2-abutment-connections
#17
Fariba Saleh Saber, Nader Abolfazli, Soheil Jannatii Ataei, Mahsa Taghizade Motlagh, Vahede Gharekhani
Background. Since the misfit of crown has an important role in clinical performance of implant-supported prostheses, and due to the impact of the settling effect on misfit, the aim of this study was to investigate the impact of torque forces on the total lengths of narrow and short implant abutments in different internal implant‒abutment connections. Methods. In four different implant‒abutment connections, 8 analog implants with a normal diameter (4 mm) and narrow abutment (4.5 mm) were selected from groups of internal hex, internal octagon, morse hex 6° and morse hex 11°...
2017: Journal of Dental Research, Dental Clinics, Dental Prospects
https://www.readbyqxmd.com/read/28733967/mass-defect-from-nuclear-physics-to-mass-spectral-analysis
#18
Soheil Pourshahian
Mass defect is associated with the binding energy of the nucleus. It is a fundamental property of the nucleus and the principle behind nuclear energy. Mass defect has also entered into the mass spectrometry terminology with the availability of high resolution mass spectrometry and has found application in mass spectral analysis. In this application, isobaric masses are differentiated and identified by their mass defect. What is the relationship between nuclear mass defect and mass defect used in mass spectral analysis, and are they the same? Graphical Abstract ᅟ...
July 21, 2017: Journal of the American Society for Mass Spectrometry
https://www.readbyqxmd.com/read/28711019/photo-catalytic-anti-bacterial-and-anti-cancer-properties-of-phyto-mediated-synthesis-of-silver-nanoparticles-from-artemisia-tournefortiana-rchb-extract
#19
Fahimeh Baghbani-Arani, Rabee Movagharnia, Alireza Sharifian, Soheil Salehi, Seyed Ataollah Sadat Shandiz
Metal nanoparticles have largely been investigated due to their potential medicinal activities. This study demonstrates the biological properties of green-synthesized silver nanoparticles (AgNPs) by using Artemisia tournefortiana Rchb ethanol extract. Instrumentations such as ultraviolet-visible spectra analysis, high-resolution transmission electron microscopy, scanning electron microscopy, energy-dispersive X-ray analysis, X-ray diffraction, and Fourier transform infrared spectroscopy were used to reveal the synthesized AgNPs...
July 6, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28702157/food-bioactive-componts-a-possible-adjuvant-for-h-pylori-eradication
#20
Soheil Ebrahimpour, Haleh Esmaeili, Reza Ghadimi
No abstract text is available yet for this article.
2017: Caspian Journal of Internal Medicine
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