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https://www.readbyqxmd.com/read/27876251/-food-protein-induced-enterocolitis-syndrome-a-case-report-of-diarrhea-with-hypovolemic-shock-and-methemoglobinemia
#1
L Genere, N Pecciarini, N Peretti, F Villard, A Lachaux
We report on the case of a young infant with chronic diarrhea that worsened and turned into hypovolemic shock with methemoglobinemia. We underline and discuss the main features of food protein-induced enterocolitis syndrome (FPIES). FPIES is a non-IgE-mediated food allergy involving tumor necrosis factor-alpha (TNF-α). Many triggering foods exist but cow's milk, as in the case reported herein, is one of the most frequent. It can start early or be delayed and start around the average age of 5 months. Symptoms are nonspecific with diarrhea and vomiting, but in the presence of methemoglobinemia, the diagnosis must be seriously considered...
November 18, 2016: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/27853717/amiata-donkey-milk-chain-animal-health-evaluation-and-milk-quality
#2
Giuseppe Ragona, Franco Corrias, Martina Benedetti, Maria Paladini, Federica Salari, Lolanda Altomonte, Mina Martini
This study presents an investigation of Amiata donkey health and quality of milk for human consumption. Thirty-one lactating dairy jennies were examined. The following samples were collected: faecal samples from the rectum of animals for parasitological examination; cervical swabs for the detection of bacteria causing reproductive disorders; and blood samples for serological diagnosis of main zoonotic (Brucella spp., Leptospira spp.) and donkey abortion agents (Brucella spp., Leptospira spp., Salmonella abortus equi, Equine viral arterithis virus, Equine herpesvirus type 1)...
June 3, 2016: Italian Journal of Food Safety
https://www.readbyqxmd.com/read/27849231/cow-s-milk-allergy-evaluating-tolerance-through-skin-prick-test
#3
Flavia Valença de Oliveira Neves, Cleonir de Moraes Lui Beck, Andrea Keiko Fujinami Gushken, Glauce Hiromi Yonamine, Ana Paula Beltran Moschione Castro, Mayra de Barros Dorna, Cristiane de Jesus Nunes Dos Santos, Antonio Carlos Pastorino
Objective: To evaluate the wheal diameter in allergy skin-prick tests (SPT) with cow's milk extract (CM) comparing tolerant and persistent patients. Method: A retrospective cohort study involving database analysis of children with diagnosis of cow's milk protein allergy (CMPA) mediated by immunoglobulin E in a specialized outpatient clinic that regularly performed SPT between January 2000 and July 2015. Patients were allocated into two groups: tolerant or persistent...
September 2016: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/27799957/prospective-evaluation-of-testing-with-baked-milk-to-predict-safe-ingestion-of-baked-milk-in-unheated-milk-allergic-children
#4
Allison Kwan, Maria Asper, Sasson Lavi, Elana Lavine, David Hummel, Julia E Upton
BACKGROUND: Cow's milk allergy is one of the most common food allergies affecting young children. A subset of milk-allergic individuals can eat baked milk without allergic symptoms which is beneficial in terms of prognostication and liberalization of the diet. A retrospective study suggested that skin prick testing (SPT) with a baked milk (muffin) slurry may provide a sensitive means of predicting the outcome of a medically supervised baked milk oral food challenge. We evaluated the predictive value of SPT with baked milk to identify unheated milk-allergic children who are able to safely eat baked milk...
2016: Allergy, Asthma, and Clinical Immunology
https://www.readbyqxmd.com/read/27741063/iodine-status-and-growth-in-0-2-year-old-infants-with-cow-s-milk-protein-allergy
#5
Rut Anne Thomassen, Janne Anita Kvammen, Mari Borge Eskerud, Pétur Benedikt Júlíusson, Christine Henriksen, Jarle Rugtveit
OBJECTIVES: To investigate iodine status and growth in cow's milk protein allergic infants and to identify potential predictors of iodine status and growth. METHODS: Fifty-seven infants under two years of age were included in an observational cross-sectional study. Two spot urine samples were collected and analysed for iodine, together with a three-day food record and a food frequency questionnaire. Urine iodine concentrations were compared to the WHO cut-off values for iodine deficiency...
October 12, 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27738596/middle-east-consensus-statement-on-the-diagnosis-and-management-of-functional-gastrointestinal-disorders-in-12-months-old-infants
#6
Yvan Vandenplas, Muath Abdurrahman Alturaiki, Wafaa Al-Qabandi, Fawaz AlRefaee, Ziad Bassil, Bassam Eid, Ahmed El Beleidy, Ali Ibrahim Almehaidib, Pierre Mouawad, Maroun Sokhn
This paper covers algorithms for the management of regurgitation, constipation and infantile colic in infants. Anti-regurgitation formula may be considered in infants with troublesome regurgitation, while diagnostic investigations or drug therapy are not indicated in the absence of warning signs. Although probiotics have shown some positive evidence for the management of functional gastrointestinal disorders (FGIDs), the evidence is not strong enough to make a recommendation. A partially hydrolyzed infant formula with prebiotics and β-palmitate may be considered as a dietary intervention for functional constipation in formula fed infants...
September 2016: Pediatric Gastroenterology, Hepatology & Nutrition
https://www.readbyqxmd.com/read/27646861/what-s-in-the-bottle-a-review-of-infant-formulas
#7
Kelly Green Corkins, Teresa Shurley
Infant formulas are designed to be a substitute for breast milk. Since they are sole source of nutrition for growing and developing infants, they are highly regulated by the government. All ingredients in infant formulas must be considered "generally recognized as safe." Manufacturers are continually modifying their products to make them more like breast milk. Functional ingredients added to infant formula include long-chain polyunsaturated fatty acids, nucleotides, prebiotics, and probiotics. The most common breast milk substitutes are standard cow's milk-based term infant formulas, which include subcategories of organic and breast milk supplementation, and come in standard dilutions of 19 or 20 calories per ounce...
September 19, 2016: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/27642151/-infant-food-diversification-assessment-of-practices-in-relation-to-french-recommendations-in-pediatricians-and-pediatric-residents-in-southern-france
#8
T Banti, A Carsin, B Chabrol, R Reynaud, A Fabre
: Infant food diversification has undergone a rapid succession of good practice recommendations in France, but there has been no assessment of pediatrician practices on food diversification. OBJECTIVE: To assess the practices of pediatricians in relation to current recommendations of the French Society of Pediatrics on infant food diversification. METHODS: This was an observational study conducted from 1 November 2014 to 31 March 2015. The study population consisted of 97 pediatricians in the Var department and 84 pediatric residents assigned to the University of Aix-Marseille in France...
October 2016: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/27634007/-clinical-characteristics-and-management-of-infants-less-than-1-year-old-suspected-with-allergy-to-cow-s-milk-protein
#9
Germán Errázuriz, Yalda Lucero, Sergio Ceresa, Mónica Gonzalez, Maureen Rossel, Andrés Vives
INTRODUCTION: Cow's milk protein allergy (CMPA) is highly prevalent in infants (2-5%). It has a wide clinical spectrum, and confirmation through an oral food challenge (OFC) is relevant for its differential diagnosis. Information on this topic is scarce in Chile. OBJECTIVE: To describe the demographic and clinical features of infants with suspected CMPA. PATIENTS AND METHOD: A retrospective study of patients<1 year-old, treated for suspected CMPA between 2009 and 2011...
September 12, 2016: Revista Chilena de Pediatría
https://www.readbyqxmd.com/read/27624222/eosinophilia-in-infants-with-food-protein-induced-enterocolitis-syndrome-in-japan
#10
Mitsuaki Kimura, Masaki Shimomura, Hideaki Morishita, Takaaki Meguro, Shiro Seto
BACKGROUND: Many Japanese infants with food protein-induced enterocolitis syndrome (FPIES) show eosinophilia, which has been thought to be a characteristic of food protein-induced proctocolitis (FPIP). METHODS: To elucidate the characteristics of eosinophilia in Japanese FPIES patients, 113 infants with non-IgE-mediated gastrointestinal food allergy due to cow's milk were enrolled and classified into FPIES (n = 94) and FPIP (n = 19). RESULTS: The percentage of peripheral blood eosinophils (Eo) was increased in most FPIES patients (median, 7...
September 10, 2016: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/27622938/breastfeeding-and-il-10-levels-in-children-affected-by-cow-s-milk-protein-allergy-a-restrospective-study
#11
Sara Manti, Vassilios Lougaris, Caterina Cuppari, Lucia Tardino, Valeria Dipasquale, Teresa Arrigo, Carmelo Salpietro, Salvatore Leonardi
AIM: To assess the protective role of breast-feeding in infants with CMPA-related AEDS as well as IL-10 utility as marker of disease evolution. METHODS: 64 breast-feeding children with CMPA-related AEDS (31 males and 33 females; mean age 5.56±2.41months; 21 mild AEDS; 25 moderate AEDS; 18 severe AEDS) and 60 artificial feeding babies (33 males and 27 females; mean age 6.01±2.08months; 26 mild AEDS; 19 moderate AEDS; 15 severe AEDS) were evaluated. In all patients serum IL-10 levels were detected...
September 8, 2016: Immunobiology
https://www.readbyqxmd.com/read/27612000/probabilistic-modelling-to-assess-exposure-to-3-artificial-sweeteners-of-young-irish-patients-aged-1-3-years-with-pku-and-cmpa
#12
Aaron J O'Sullivan, Sandrine Pigat, Cian O'Mahony, Michael J Gibney, Aideen I McKevitt
The choice of suitable normal foods is limited for individuals with particular medical conditions e.g. inborn errors of metabolism (phenylketonuria, PKU) or severe cow's milk protein allergy (CMPA). Patients may have dietary restrictions and exclusive or partial replacement of specific food groups with specially formulated products to meet particular nutrition requirements. Artificial sweeteners are used to improve the appearance and palatability of such food products to avoid food refusal and ensure dietary adherence...
September 9, 2016: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/27603546/identification-of-the-critical-amino-acid-residues-of-immunoglobulin-e-and-immunoglobulin-g-epitopes-in-%C3%AE-lactalbumin-by-alanine-scanning-analysis
#13
Cong Yanjun, Zhou Shengyun, Li Linfeng
α-Lactalbumin represents one of the major allergens causing cow milk allergy. Few studies have clearly evaluated immunological relationships between immunoglobulin E (IgE) and immunoglobulin G (IgG)-binding epitopes of α-lactalbumin. IgE- and IgG-binding epitopes were immunolabeled with individual sera from cow milk-allergic patients. Alanine scanning of immunodominant epitopes was used to identify the critical amino acid (aa). Our initial data revealed Val(8) , Phe(9) , Arg(10) , Tyr(103) , Leu(105) , and His(107) were the critical aa for IgE-binding epitope...
October 2016: Journal of Food Science
https://www.readbyqxmd.com/read/27582492/cow-s-milk-protein-allergy
#14
Grace Mousan, Deepak Kamat
Cow's milk protein allergy (CMPA) is a common condition encountered in children with incidence estimated as 2% to 7.5% in the first year of life. Formula and breast-fed babies can present with symptoms of CMPA. It is important to accurately diagnose CMPA to avoid the consequences of either under- or overdiagnosis. CMPA is classically categorized into immunoglobulin E (IgE)- or non-IgE-mediated reaction that vary in clinical manifestations, diagnostic evaluation, and prognosis. The most commonly involved systems in patients with CMPA are gastrointestinal, skin, and respiratory...
October 2016: Clinical Pediatrics
https://www.readbyqxmd.com/read/27568925/presumed-allergic-proctocolitis-resolves-with-probiotic-monotherapy-a-report-of-4-cases
#15
Victoria J Martin, Wayne G Shreffler, Qian Yuan
BACKGROUND The prevalence of allergic diseases has been dramatically rising in the United States and other developed nations over recent decades. Growing evidence suggests a partial role for the microbiome in the development of these allergic diseases. Food protein-induced allergic proctocolitis (AP) (also referred to as cow's milk protein intolerance or allergy) is among the earliest and most common food allergic diseases of infancy, yet its pathophysiology is not well understood. The currently accepted clinical practice is to restrict the diet until 12 months of age...
2016: American Journal of Case Reports
https://www.readbyqxmd.com/read/27545065/humoral-and-cellular-responses-to-casein-in-patients-with-food-protein-induced-enterocolitis-to-cow-s-milk
#16
Jean Christoph Caubet, Ramon Bencharitiwong, Andrew Ross, Hugh A Sampson, M Cecilia Berin, Anna Nowak-Węgrzyn
BACKGROUND: Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-mediated food allergy manifesting within 1 to 4 hours of food ingestion with repetitive emesis and lethargy. OBJECTIVE: We sought to characterize immune responses to casein in children with FPIES caused by cow's milk (CM). METHODS: Total IgE and IgM, CM-specific IgG, and casein-specific IgE, IgG, IgG4, and IgM levels, as well as immunoglobulin free light chains, were measured in both patients with active and those with resolved CM-FPIES...
July 15, 2016: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27526059/evaluation-of-an-amino-acid-based-formula-in-infants-not-responding-to-extensively-hydrolyzed-protein-formula
#17
Jon Vanderhoof, Nancy Moore, Delphine de Boissieu
Nearly 2% to 3% of infants and children younger than 3 years have confirmed cow's milk protein allergy with multiple clinical presentations including atopic dermatitis (AD), diarrhea, and vomiting/spitting up. Although most infants with cow's milk protein allergy experience clinical improvement with the use of an extensively hydrolyzed (EH) formula, highly sensitive infants may require an amino acid-based formula. In this observational, prospective study, 30 infants (1-12 months of age) with a history of weight loss and persistent allergic manifestations while on an EH formula were provided an amino acid-based formula for 12 weeks...
November 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27498217/awareness-of-allergic-enterocolitis-among-primary-care-paediatricians-a-web-based-pilot-survey
#18
P Comberiati, M Landi, A Martelli, G L Piacentini, C Capristo, G Paiola, D G Peroni
BACKGROUND: Allergic enterocolitis, also known as food protein-induced enterocolitis syndrome (FPIES), is an increasingly reported and potentially severe non-IgE mediated food allergy of the first years of life, which is often misdiagnosed due to its non-specific presenting symptoms and lack of diagnostic guidelines. OBJECTIVE: We sought to determine the knowledge of clinical, diagnostic and therapeutic features of FPIES among Italian primary-care paediatricians...
September 2016: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/27437928/amino-acid-based-formula-in-cow-s-milk-allergy-long-term-effects-on-body-growth-and-protein-metabolism-a-randomized-trial
#19
Roberto Berni Canani, Rita Nocerino, Tullio Frediani, Sandra Lucarelli, Carmen Di Scala, Elena Varin, Ludovica Leone, Antonella Muraro, Carlo Agostoni
OBJECTIVES: The long-term effects of amino acid-based formula (AAF) in the treatment of cow's milk allergy (CMA) is largely unexplored. This study comparatively evaluates body growth and protein metabolism in CMA children treated with AAF or with extensively hydrolysed whey formula (eHWF), and healthy controls (HCs). METHODS: A 12-month multicentre randomised control trial (RCT) was conducted in outpatients with CMA (aged 5-12 m) randomised in two groups, treated with AAF (Group 1) and eHWF (Group 2), and compared with HCs (Group 3) fed with follow-on (if age <12 m) or growing-up formula (if age >12 m)...
July 20, 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27397020/breastfeeding-and-complementary-feeding
#20
Christine Prell, Berthold Koletzko
BACKGROUND: Proper infant nutrition promotes healthy growth and development and lowers the risk of disease in later life. METHODS: This review is based on pertinent articles retrieved by a selective search, including guidelines, meta-analyses, and systematic reviews. RESULTS: Infants should be exclusively breast-fed until at least the age of 4 months. Infants who are no longer being breast-fed, or no longer exclusively so, should be given commercially available low-protein infant formula containing long-chain polyunsaturated fatty acids...
June 24, 2016: Deutsches Ärzteblatt International
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