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JOURNAL ARTICLE
Jean Toniolo, Edgard Brice Ngoungou, Pierre-Marie Preux, Pascale Beloni
BACKGROUND: 31.4 million people in low- and middle-income countries die from chronic diseases annually, particularly in Africa. To address this, strategies such as task-shifting from doctors to nurses have been proposed and have been endorsed by the World Health Organization as a potential solution; however, no comprehensive review exists describing the extent of nurse-led chronic disease management in Africa. AIMS: This study aimed to provide a thorough description of the current roles of nurses in managing chronic diseases in Africa, identify their levels of knowledge, the challenges, and gaps they encounter in this endeavor...
2024: PloS One
#2
JOURNAL ARTICLE
Health care managers' perspectives on workforce licensing practice in Ethiopia: A qualitative study.
Eshetu Cherinet Teka, Meron Yakob Gebreyes, Endalkachew Tsedal Alemneh, Biruk Hailu Tesfaye, Firew Ayalew Desta, Yohannes Molla Asemu, Ermias Gebreyohannes Wolde, Wondimu Daniel Ashena, Samuel Mengistu, Tewodros Abebaw Melese, Fikadie Dagnew Biset, Bezawit Worku Degefu, Bethlehem Bizuayehu Kebede, Tangut Dagnew Azeze, Wudasie Teshome Shewatatek, Melese Achamo Seboka, Abera Bezabih Gebreegzi, Mekonnen Desie Degebasa, Tsedale Tafesse Lemu, Yeshiwork Eshetu Abebe, Matias Azanaw Alayu, Fatuma Ahmed Ebrahim, Eden Workneh Sahlemariam, Genet Kifle Woldesemayat, Hailemaryam Balcha Admassu, Bethlehem Shikabaw Chekol
BACKGROUND: Professional licensing bodies are valuable sources for tracking the health workforce, as many skilled health-care providers require formal training, registration, and licensure. Regulatory activities in Ethiopia were not effectively implemented due to poor follow-up and gaps in skilled human resources, budget, and information technology infrastructure. OBJECTIVE: The aim of this study was to explore and describe the lived experiences and challenges faced by health care managers in health professionals' licensure practices in Ethiopia...
2024: PloS One
#3
JOURNAL ARTICLE
Hela Ghali, Aymen El Hraiech, Hend Ben Souda, Majdi Karray, Bruno Pavy, Chekib Zedini
BACKGROUND: Faced with the increase in the number of chronic diseases with the aging of the population, and with the observation of the insufficiency of therapeutic control, a new need has emerged, that of having a patient as a partner in care. METHODS: This study is a randomized controlled trial. Patients with coronary heart disease will be recruited from one clinical site and randomly assigned into two groups: the intervention group and the control group. All participants will be followed up for a total of one year (with three-time points for data collection)...
2024: PloS One
#4
JOURNAL ARTICLE
Siliang Luan, Zhongtai Jiang
Globally, traffic accidents on the highway network contribute significantly to a high fatality rate, drawing considerable attention from health institutions. The efficiency of transportation plays a vital role in mitigating the severe consequences of these incidents. This study delves into the issues of emergency vehicles experiencing delays despite having priority. Therefore, we construct mixed-integer linear programming with semi-soft time windows (MIPSSTW) model for optimizing emergency vehicle routing in highway incidents...
2024: PloS One
#5
JOURNAL ARTICLE
Laura J McGowan, Deepti A John, Ryan P W Kenny, Emma C Joyes, Emma A Adams, Hosein Shabaninejad, Catherine Richmond, Fiona R Beyer, David Landes, Richard G Watt, Falko F Sniehotta, Martha Paisi, Claire Bambra, Dawn Craig, Eileen Kaner, Sheena E Ramsay
BACKGROUND: People experiencing homelessness co-occurring with substance use or offending ('severe and multiple disadvantage' SMD) often have high levels of poor oral health and related health behaviours (particularly, substance use, smoking, poor diet). This systematic review aimed to assess the effectiveness and cost-effectiveness of interventions in adults experiencing SMD to improve oral health and related health behaviours. METHODS AND FINDINGS: From inception to February 2023, five bibliographic databases (MEDLINE, EMBASE, PsycINFO, CINAHL, and Scopus) and grey literature were searched...
2024: PloS One
#6
JOURNAL ARTICLE
Christine Rousset-Jablonski, Barbara Lortal, Sophie Lantheaume, Laurent Arnould, Hélène Simon, Anne-Sophie Tuszynski, Mélanie Courtier, Soukayna Debbah, Marc Lefrançois, Sita Balbin, Anne-Sophie Kably, Alain Toledano
PURPOSE: To improve the quality of care for patients with breast cancer, an analysis of the health-care pathway, considering feedback from both health-care practitioners (HCPs) and patients, is needed. METHODS: Between 2020 and 2022, we conducted a survey at French breast cancer centers and analyzed information from questionnaires completed by HCPs and patients. We collected information on center organization, diagnostic processes, treatment decisions and modalities, supportive care, patient advocacy groups, and work issues...
April 18, 2024: Breast Cancer: the Journal of the Japanese Breast Cancer Society
#7
Karen Spilsbury, Andy Charlwood, Carl Thompson, Kirsty Haunch, Danat Valizade, Reena Devi, Cornell Jackson, David Phillip Alldred, Antony Arthur, Lucy Brown, Paul Edwards, Will Fenton, Heather Gage, Matthew Glover, Barbara Hanratty, Julienne Meyer, Aileen Waton
BACKGROUND: Quality of life and care varies between and within the care homes in which almost half a million older people live and over half a million direct care staff (registered nurses and care assistants) work. The reasons are complex, understudied and sometimes oversimplified, but staff and their work are a significant influence. OBJECTIVE(S): To explore variations in the care home nursing and support workforce; how resident and relatives' needs in care homes are linked to care home staffing; how different staffing models impact on care quality, outcomes and costs; how workforce numbers, skill mix and stability meet residents' needs; the contributions of the care home workforce to enhancing quality of care; staff relationships as a platform for implementation by providers...
April 2024: Health Soc Care Deliv Res
#8
JOURNAL ARTICLE
Nimish N Shah, Lama Ghazi, Yu Yamamoto, Sanchit Kumar, Melissa Martin, Michael Simonov, Ralph J Riello Iii, Kamil F Faridi, Tariq Ahmad, F Perry Wilson, Nihar R Desai
BACKGROUND: Lipid-lowering therapy (LLT) is underutilized for very high-risk atherosclerotic cardiovascular disease. PROMPT-LIPID (PRagmatic Trial of Messaging to Providers about Treatment of HyperLIPIDemia) sought to determine whether electronic health record (EHR) alerts improve 90-day LLT intensification in patients with very high-risk atherosclerotic cardiovascular disease. METHODS: PROMPT-LIPID was a pragmatic trial in which cardiovascular and internal medicine clinicians within Yale New Haven Health (New Haven, CT) were cluster-randomized to receive an EHR alert with individualized LLT recommendations or no alert for outpatients with very high-risk atherosclerotic cardiovascular disease and LDL-C (low-density lipoprotein cholesterol), ≥70 mg/dL...
April 18, 2024: Circulation. Cardiovascular Quality and Outcomes
#9
JOURNAL ARTICLE
Kuntal Sen, Rima Izem, Yuelin Long, Jiji Jiang, Laura L Konczal, Robert J McCarter, Andrea L Gropman, Jirair K Bedoyan
BACKGROUND: Ornithine transcarbamylase deficiency (OTCD) due to an X-linked OTC mutation, is responsible for moderate to severe hyperammonemia (HA) with substantial morbidity and mortality. About 80% of females with OTCD remain apparently "asymptomatic" with limited studies of their clinical characteristics and long-term health vulnerabilities. Multimodal neuroimaging studies and executive function testing have shown that asymptomatic females exhibit limitations when stressed to perform at higher cognitive load and had reduced activation of the prefrontal cortex...
April 2024: Molecular Genetics & Genomic Medicine
#10
Javeed Iqbal, Muhammad Mohsin Khan, Abdulnasser Thabet, Kazim Mohammed, Gianluca Scalia, Bipin Chaurasia
KEY CLINICAL MESSAGE: Successful management of cervical tuberculosis and severe kyphosis was achieved using a PEEK expandable cage and titanium plate, demonstrating favorable outcomes in restoring cervical alignment and stability. This approach represents a promising alternative for addressing complex cervical pathologies, highlighting the potential of PEEK-based interventions in surgical management. ABSTRACT: Cervical tuberculosis can lead to severe vertebral destruction and kyphosis, posing challenges in surgical management...
April 2024: Clinical Case Reports
#11
Satomi Mizutani, Hidehiko Kuribayashi, Noriyuki Saeki, Hideki Ito, Yasutaka Nakamura, Makoto Masuda, Yoshito Kamio, Masashi Kawamoto, Tatsuji Enomoto
KEY CLINICAL MESSAGE: Even in the absence of other symptoms or other pulmonary manifestations suggesting Sjögren's syndrome (SS), it is necessary to include SS in the differential diagnosis of diffuse cystic lung disease (CLD). ABSTRACT: A case of SS that presented initially with diffuse CLD is reported. This case is considered rare because diffuse pulmonary cysts were observed in the early stage with few symptoms, only cysts were observed without other lung lesions on imaging, cyst formation was histologically considered to be alveolar loss, and airway lesions not observed on imaging were suspected based on lung function testing...
April 2024: Clinical Case Reports
#12
Samuel Addisu Abera, Amanuel Kassa Tadesse, Kirubel Addisu Abera, Kassa Berie Zegeye, Mohammed Alemu Ibrahim, Ashenafi Amsalu Feleke, Cheru Lilay Gebrehiwet, Segenet Bizuneh Mengistu, Hirut Tesfahun Alemu, Yohannis Derbew Molla
KEY CLINICAL MESSAGE: Duodenal GISTs are rare and challenging tumors. Acute life-threatening upper GI bleeding is a possible presentation of duodenal GISTs. Surgery is the standard treatment for localized duodenal GISTs. Imatinib is an effective adjuvant therapy for duodenal GISTs. ABSTRACT: GIST is the most common mesenchymal neoplasm of the gastrointestinal tract, accounting for 1%-2% of gastrointestinal tumors. They originate from the interstitial cells of Cajal and are rare in patients younger than 30 years...
April 2024: Clinical Case Reports
#13
Alex José Castellón Méndez, Allan Bodán Campbell, Victor Rosales Obregón, Mohammed Zahran
KEY CLINICAL MESSAGE: Rare yet significant, this case sheds light on the uncommon presentation of Waldmann's disease in adults, showcasing the diagnostic challenges it poses. A multidisciplinary approach, integrating clinical, endoscopic, histological, and radiological evaluations, is crucial for accurate diagnosis and management. Further research is needed to deepen our understanding of this complex disorder. ABSTRACT: Waldmann's disease, or primary intestinal lymphangiectasia, is a rare disorder characterized by protein-losing enteropathy due to dilation and leakage of intestinal lymphatic vessels...
April 2024: Clinical Case Reports
#14
JOURNAL ARTICLE
Juan Carlos Núñez-Enríquez, Rubí Romo-Rodríguez, Pedro Gaspar-Mendoza, Gabriela Zamora-Herrera, Lizeth Torres-Pineda, Jiovanni Amador-Cardoso, Jebea A López-Blanco, Laura Alfaro-Hernández, Lucero López-García, Arely Rosas-Cruz, Dulce Rosario Alberto-Aguilar, César Omar Trejo-Pichardo, Dalia Ramírez-Ramírez, Astin Cruz-Maza, Janet Flores-Lujano, Nuria Luna-Silva, Angélica Martínez-Martell, Karina Martínez-Jose, Anabel Ramírez-Ramírez, Juan Carlos Solis-Poblano, Patricia Zagoya-Martínez, Vanessa Terán-Cerqueda, Andrea Huerta-Moreno, Álvaro Montiel-Jarquín, Miguel Garrido-Hernández, Raquel Hernández-Ramos, Daniela Olvera-Caraza, Cynthia Shanat Cruz-Medina, Enoch Alvarez-Rodríguez, Lénica Anahí Chávez-Aguilar, Wilfrido Herrera-Olivares, Brianda García-Hidalgo, Lena Sarahí Cano-Cuapio, Claudia Guevara-Espejel, Gerardo Juárez-Avendaño, Juan Carlos Balandrán, Ma Del Rocío Baños-Lara, Mariana Cárdenas-González, Elena R Álvarez-Buylla, Sonia Mayra Pérez-Tapia, Diana Casique-Aguirre, Rosana Pelayo
The main objective of the National Project for Research and Incidence of Childhood Leukemias is to reduce early mortality rates for these neoplasms in the vulnerable regions of Mexico. This project was conducted in the states of Oaxaca, Puebla, and Tlaxcala. A key strategy of the project is the implementation of an effective roadmap to ensure that leukemia patients are the target of maximum benefit of interdisciplinary collaboration between researchers, clinicians, surveyors, and laboratories. This strategy guarantees the comprehensive management of diagnosis and follow-up samples of pediatric patients with leukemia, centralizing, managing, and analyzing the information collected...
2024: Frontiers in Oncology
#15
Hannah Lineberger, Ryan Cronk, Sena Kpodzro, Aaron Salzberg, Darcy M Anderson
INTRODUCTION: Environmental health services (e.g., water, sanitation, hygiene, cleaning, waste management) in healthcare facilities are important to improve health outcomes and strengthen health systems, but coverage gaps remain. The World Health Organization and United Nations Children's Fund developed WASH FIT, a quality improvement tool, to help assess and improve environmental health services. Fifty-three countries have adopted it. However, there is little evidence of its effectiveness...
April 6, 2024: medRxiv
#16
REVIEW
Zhuce Shao, Huanshen Gao, Benlong Wang, Shenqi Zhang
Osteoporosis, arthritis, and fractures are examples of orthopedic illnesses that not only significantly impair patients' quality of life but also complicate and raise the expense of therapy. It has been discovered in recent years that the pathophysiology of orthopedic disorders is significantly influenced by the microbiota. By employing machine learning and deep learning techniques to conduct a thorough analysis of the disease-causing microbiome, we can enhance our comprehension of the pathophysiology of many illnesses and expedite the creation of novel treatment approaches...
2024: Frontiers in Cellular and Infection Microbiology
#17
JOURNAL ARTICLE
Shuo Tian, Haitao Zhong, Mengyue Yin, Pei Jiang, Qiao Liu
PURPOSE: This study aims to conduct a comprehensive cost-effectiveness comparison between novel oral anticoagulants (NOACs) and warfarin in Chinese patients with left ventricular thrombosis (LVT). By incorporating the impact of volume-based procurement (VBP) policy for pharmaceuticals in China, this analysis intends to provide crucial insights for informed healthcare decision-making. PATIENTS AND METHODS: A Markov model was employed to simulate the disease progression of LVT over a 54-week time horizon, using weekly cycles and six mutually exclusive health states...
2024: Risk Management and Healthcare Policy
#18
REVIEW
Tina M Savvaides, Michelle R Demetres, Kerri I Aronson
BACKGROUND: Understandable, comprehensive, and accessible educational materials for patients with interstitial lung disease (ILD) are lacking. Patients consistently ask for improved access to evidence-based information about ILD. Nonetheless, few research studies focus directly on developing and evaluating interventions to improve patient knowledge. OBJECTIVE: We describe the current landscape of patient education in ILD, identify gaps in current approaches to information delivery, and provide frameworks to address these challenges through novel educational tools...
March 2024: ATS scholar
#19
JOURNAL ARTICLE
Merel Laauwen, Saskia Nowicki
Progress toward universal access to safe drinking water depends on rural water service delivery models that incorporate water safety management. Water supplies of all types have high rates of fecal contamination unless water safety risks are actively managed through water source protection, treatment, distribution, and storage. Recognizing the role of treatment within this broader risk-based framework, this study focuses on the implementation of passive chlorination and ultraviolet (UV) disinfection technologies in rural settings...
April 12, 2024: ACS ES&T water
#20
JOURNAL ARTICLE
Zhongmin Fu, Yan Xie, Peifang Li, Menghui Gao, Jiali Chen, Ning Ning
BACKGROUND: The use of multidisciplinary treatment programs in out-of-hospital healthcare is a new area of research. Little is known about the benefits of this method in the management of discharged patients undergoing cervical spondylosis surgery. OBJECTIVE: This study aimed to explore the effect of a contracted-based, multidisciplinary follow-up plan in patients after cervical spondylosis surgery. METHODS: This non-blinded non-randomized controlled study was conducted with 88 patients (44 in the intervention group, 44 in the control group)...
2024: Frontiers in Medicine
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