keyword
https://read.qxmd.com/read/38537226/can-platelet-activation-markers-predict-preeclampsia-and-or-its-severity
#1
JOURNAL ARTICLE
Tuğçe Arslanoğlu, Kübra Kurt-Bilirer, Nihal Çallıoğlu, Selvi Aydın-Şenel, Işıl Turan-Bakırcı, İklil N Koç-Erol, Emre Kar, Zeliha Bayram, Ibrahim Polat
OBJECTIVE: This study aimed to evaluate the value of platelet activation markers in predicting preeclampsia and its severity. Preeclampsia is a serious pregnancy complication that affects 3-5% of pregnancies and can lead to significant morbidity and mortality for both the mother and the fetus. METHODS: The study included 99 patients diagnosed with preeclampsia and 60 healthy pregnant women as a control group. Platelet activation markers such as mean platelet volume (MPV), platelet distribution width (PDW), platelet count, and plateletcrit were evaluated along with other clinical parameters...
2024: Cirugia y Cirujanos
https://read.qxmd.com/read/38537035/polyphenol-analysis-in-human-milk-by-a-rapid-cost-effective-and-accurate-micromethod-translational-development
#2
JOURNAL ARTICLE
Mariela Valentina Cortez, Ana Veronica Scotta, Agustín Ramiro Miranda, Elio Andrés Soria
OBJECTIVE: To develop a rapid method for analysing polyphenols, which are potentially active antioxidants against neonatal oxidative stress, from small human milk (HM) volumes. METHODS: Acid and alkaline extractions were compared using two dyes: Folin-Ciocalteu and Fast Blue BB. Linearity, sensitivity, recovery percentage, polyphenol content, precision, and stability were assessed in 14 HM samples and compared using the Kruskal-Wallis H test (p<0.05). The best technique was applied to 284 HM samples to determine their polyphenolic content and its association with maternal diet by multifactorial linear regression...
2024: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
https://read.qxmd.com/read/38537008/impact-of-anthro-metabolic-indices-and-gestational-weight-gain-on-maternal-and-neonatal-outcomes-a-prospective-observational-study
#3
JOURNAL ARTICLE
Esra Keles, Leyla Kaya, Neşe Yakşi, Zahide Kaya, Önder Tosun
OBJECTIVE: The aim of this study was to examine the relationship of anthro-metabolic indices on maternal and neonatal outcomes. METHODS: This prospective observational study was conducted on healthy mother-baby pairs between January 1, 2023 and July 1, 2023. Detailed sociodemographic information was collected through an interview with the mother. Clinical, biochemical, obstetric, fetal, and neonatal outcomes were abstracted from hospital medical records. Anthropometric measurements were obtained from the examination of mother-baby pairs...
2024: Revista da Associação Médica Brasileira
https://read.qxmd.com/read/38537006/effect-of-mode-of-delivery-on-postpartum-health-related-quality-of-life
#4
JOURNAL ARTICLE
Esra Keles, Leyla Kaya, Neşe Yakşi, Zahide Kaya
OBJECTIVE: The aim of the study was to explore the impact of mode of delivery on health-related quality of life in mothers. METHODS: This cross-sectional study was conducted between May and August 2022 on healthy singleton pregnant women aged between 18 and 45 years. Data on socio-demographic variables, clinic features, pregnancy and birth characteristics, and neonatal outcomes were collected. Health-related quality of life was assessed by using EQ-5D-5L questionnaire...
2024: Revista da Associação Médica Brasileira
https://read.qxmd.com/read/38536979/exclusive-breastfeeding-duration-within-a-cohort-of-indigenous-terena-living-in-the-urban-area-of-campo-grande-central-west-region-brazil
#5
JOURNAL ARTICLE
Deise Bresan, Maurício Soares Leite, Teresa Gontijo de Castro, Aline Alves Ferreira, Elenir Rose Jardim Cury
In Brazil, current information about breastfeeding indicators among indigenous living in the urban areas is lacking. This article describes the duration of exclusive breastfeeding and its associations with mother and child characteristics in a cohort of Terena infants. The study enrolled infants born between June 2017 to July 2018 (n = 42) and living in villages of the urban area of Campo Grande, Mato Grosso do Sul State, Brazil. Information was collected in four time-points. Variables on maternal sociodemographics and on maternal and child health characteristics were collected, respectively, during the antenatal and the first-month interviews...
2024: Cadernos de Saúde Pública
https://read.qxmd.com/read/38536883/maternal-and-umbilical-cord-blood-lead-levels-in-selected-informal-settlements-in-nairobi-kenya-a-cross-sectional-study
#6
JOURNAL ARTICLE
Edith A Lumumba, Anne M Riederer, John O Onyatta, Sarah Benki-Nugent, Catherine J Karr, Faridah H Were
No abstract text is available yet for this article.
March 2024: Environmental Health Perspectives
https://read.qxmd.com/read/38536856/factors-associated-with-the-uptake-of-intermittent-preventive-treatment-for-malaria-during-pregnancy-in-cameroon-an-analysis-of-data-from-the-2018-cameroon-demographic-and-health-survey
#7
JOURNAL ARTICLE
Dominique Ken Guimsop, Ange Faustine Kenmogne Talla, Haoua Kodji, Jerome Ateudjieu
Malaria in pregnancy is a major public health concern that contributes to a significant increase in maternal and child mortality and morbidity. Intermittent preventive treatment of malaria during pregnancy using sulfadoxine-pyrimethamine (IPTp-SP) is a key intervention recommended by the World Health Organization (WHO) and implemented in Cameroon to reduce the morbidity associated with malaria during pregnancy. This study aimed to assess the distribution of the poor uptake of IPTp-SP (i.e. fewer than three doses) in Cameroon and the factors associated...
2024: PLOS Glob Public Health
https://read.qxmd.com/read/38536799/pubertal-timing-a-life-course-pathway-linking-early-life-risk-to-adulthood-cardiometabolic-health
#8
JOURNAL ARTICLE
Maria E Bleil, Bradley M Appelhans, Steven E Gregorich, Robert A Hiatt, Glenn I Roisman, Cathryn Booth-LaForce
OBJECTIVE: To evaluate a series of prospective life course models testing whether the timing of pubertal development is a pathway through which prepubertal risk factors may influence adulthood cardiometabolic health. METHODS: Subjects were 655 female participants in the NICHD Study of Early Child Care and Youth Development (SECCYD) and recent SECCYD 30-year follow-up, the Study of Health in Early and Adult Life (SHINE). Prepubertal risk factors included maternal menarcheal age, child race/ethnicity, child health status indicators, and child adversity indicators...
2024: PloS One
https://read.qxmd.com/read/38536796/breastfeeding-cognitive-ability-and-residual-confounding-a-comment-on-studies-by-pereyra-el%C3%A3-as-et-al
#9
JOURNAL ARTICLE
Kimmo Sorjonen, Gustav Nilsonne, Michael Ingre, Bo Melin
Recent studies found positive effects of breastfeeding on the child's cognitive ability and educational outcomes even when adjusting for maternal cognitive ability in addition to a large number of other potential confounders. The authors claimed an important role of breastfeeding for the child's cognitive scores. However, it is well known that error in the measurement of confounders can leave room for residual confounding. In the present reanalyses, we found incongruent effects indicating simultaneous increasing and decreasing effects of breastfeeding on the child's cognitive ability and educational outcomes...
2024: PloS One
https://read.qxmd.com/read/38536791/intrauterine-and-early-life-malnutrition-in-rats-disrupts-the-circadian-rhythm-programming-of-energy-metabolites-through-adulthood
#10
JOURNAL ARTICLE
Dulce Jocelyn Bustamante-Valdez, Martin Alejandro Fuentes-Cano, Jesus Salvador Gonzalez-Ruano, Alonso Martinez-Canabal, Rene Cardenas-Vazquez, Pilar Duran
Maternal malnutrition plays a crucial role in functional development, resulting in behavioral, cognitive, and metabolic abnormalities and disturbances. "Cafeteria diet" has been linked to obesity, metabolic syndrome, diabetes, and other metabolic disruptions in the mammalian lifespan. However, there are very few reports about the effect of intrauterine and early postnatal malnutrition on the circadian rhythm programming of energy metabolites. In mammals, circadian rhythm central control is fundamental for correct interaction with the environment and physiological regulation...
2024: PloS One
https://read.qxmd.com/read/38536661/trial-of-labor-after-2-previous-cesareans-a-multicenter-study
#11
JOURNAL ARTICLE
Yael Gold Zamir, Tzuria Peled, Hila Hochler, Hen Y Sela, Ari Weiss, Michal Lipschuetz, Joshua Isaac Rosenbloom, Sorina Grisaru-Granovsky, Misgav Rottenstreich
BACKGROUND: Trial of labor after cesarean after 2 cesarean deliveries is linked to a lower success rate of vaginal delivery and higher rates of adverse obstetrical outcomes than trial of labor after cesarean after 1 previous cesarean delivery. OBJECTIVE: This study aimed to investigate the factors associated with failed trial of labor after cesarean among women with 2 previous cesarean deliveries. STUDY DESIGN: This was a multicenter retrospective cohort study, which included all women with singleton pregnancies attempting trial of labor after cesarean after 2 previous cesarean deliveries between 2003 and 2021...
December 1, 2023: American journal of obstetrics & gynecology MFM
https://read.qxmd.com/read/38536618/genome-constitution-and-evolution-of-elymus-atratus-poaceae-triticeae-inferred-from-cytogenetic-and-phylogenetic-analysis
#12
JOURNAL ARTICLE
Lu Tan, Dan-Dan Wu, Chang-Bing Zhang, Yi-Ran Cheng, Li-Na Sha, Xing Fan, Hou-Yang Kang, Yi Wang, Hai-Qin Zhang, Marcial Escudero, Yong-Hong Zhou
BACKGROUND: Elymus atratus (Nevski) Hand.-Mazz. is perennial hexaploid wheatgrass. It was assigned to the genus Elymus L. sensu stricto based on morphological characters. Its genome constitution has not been disentangled yet. OBJECTIVE: To identify the genome constitution and origin of E. atratus. METHODS: In this study, genomic in situ hybridization and fluorescence in situ hybridization, and phylogenetic analysis based on the Acc1, DMC1 and matK sequences were performed...
March 27, 2024: Genes & Genomics
https://read.qxmd.com/read/38536599/inter-district-and-wealth-related-inequalities-in-maternal-and-child-health-service-coverage-and-child-mortality-within-addis-ababa-city
#13
JOURNAL ARTICLE
Wubegzier Mekonnen, Worku Dechassa, Desalegn Y Melesse, Natalia Tejedor-Garavito, Kristine Nilsen, Theodros Getachew, Shegaw Mulu, Naod Wondrad
In sub-Saharan Africa, urban areas generally have better access to and use of maternal, newborn, and child health (MNCH) services than rural areas, but previous research indicates that there are significant intra-urban disparities. This study aims to investigate temporal trends and geographic differences in maternal, newborn, and child health service utilization between Addis Ababa's poorest and richest districts and households. A World Bank district-based poverty index was used to classify districts into the top 60% (non-poor) and bottom 40% (poor), and wealth index data from the Ethiopian Demographic and Health Survey (EDHS) was used to classify households into the top 60% (non-poor) and bottom 40% (poor)...
March 27, 2024: Journal of Urban Health
https://read.qxmd.com/read/38536597/exosomal-encapsulation-of-mir-3198-promotes-proliferation-and-migration-of-trophoblasts-in-preeclampsia
#14
JOURNAL ARTICLE
Yuchen Li, Yanling Yu, Dejun Li, Lei Li
PURPOSE: Preeclampsia (PE) is a vascular remodeling disorder cloesly linked to trophoblast dysfunction, involving defects in their proliferation, migration, and apoptosis. Maternal exosomal microRNAs (miRNAs) have been reported to play pivotal roles in the development of PE. However, the mechanism underlying the role of maternal exosomes in trophoblast dysfunction regarding the development of PE is poorly understood. METHODS: Plasma exosomes from maternal peripheral blood were collected from pregnant women with PE and from those with normal pregnancy...
March 27, 2024: Journal of Assisted Reproduction and Genetics
https://read.qxmd.com/read/38536596/pathologic-maternal-and-neonatal-outcomes-associated-with-programmed-embryo-transfer-potential-etiologies-and-strategies-for-prevention
#15
REVIEW
Kirk P Conrad, Frauke von Versen-Höynck, Valerie L Baker
PURPOSE: In the first of two companion papers, we comprehensively reviewed the recent evidence in the primary literature, which addressed the increased prevalence of hypertensive disorders of pregnancy, late-onset or term preeclampsia, fetal overgrowth, postterm birth, and placenta accreta in women conceiving by in vitro fertilization. The preponderance of evidence implicated frozen embryo transfer cycles and, specifically, those employing programmed endometrial preparations, in the higher risk for these adverse maternal and neonatal pregnancy outcomes...
March 27, 2024: Journal of Assisted Reproduction and Genetics
https://read.qxmd.com/read/38536594/pathologic-maternal-and-neonatal-outcomes-associated-with-programmed-embryo-transfer
#16
REVIEW
Kirk P Conrad, Frauke von Versen-Höynck, Valerie L Baker
PURPOSE: In this first of two companion papers, we critically review the evidence recently published in the primary literature, which addresses adverse maternal and neonatal pregnancy outcomes associated with programmed embryo transfer cycles. We next consider whether these pathological pregnancy outcomes might be attributable to traditional risk factors, unknown parental factors, embryo culture, culture duration, or cryopreservation. Finally, in the second companion article, we explore potential etiologies and suggest strategies for prevention...
March 27, 2024: Journal of Assisted Reproduction and Genetics
https://read.qxmd.com/read/38536552/il-6-enhances-the-activation-of-pi3k-akt-mtor-gsk-3%C3%AE-by-upregulating-grpr-in-hippocampal-neurons-of-autistic-mice
#17
JOURNAL ARTICLE
Heli Li, Xinyuan Wang, Cong Hu, Jinru Cui, Hao Li, Xiaoping Luo, Yan Hao
Autism spectrum disorder (ASD) is a neurological disorder associated with brain inflammation. The underlying mechanisms could be attributed to the activation of PI3K signaling in the inflamed brain of ASD. Multiple studies highlight the role of GRPR in regulating ASD like abnormal behavior and enhancing the PI3K signaling. However, the molecular mechanism by which GRPR regulates PI3K signaling in neurons of individuals with ASD is still unclear. In this study, we utilized a maternal immune activation model to investigate the effects of GRPR on PI3K signaling in the inflamed brain of ASD mice...
March 27, 2024: Journal of Neuroimmune Pharmacology: the Official Journal of the Society on NeuroImmune Pharmacology
https://read.qxmd.com/read/38536449/evaluation-of-systemic-immune-inflammation-index-for-predicting-late-onset-fetal-growth-restriction
#18
JOURNAL ARTICLE
Fahri Burcin Firatligil, Serap Topkara Sucu, Sitare Tuncdemir, Erkan Saglam, Murat Levent Dereli, Sadullah Ozkan, Yildiz Akdas Reis, Kadriye Yakut Yucel, Sevki Celen, Ali Turhan Caglar
INTRODUCTION: To determine a cut-off value for systemic immune-inflammation index (SII) (neutrophil × platelet/lymphocyte) in the prediction of fetal growth restriction (FGR). MATERIALS AND METHODS: This case-control study was conducted retrospectively at the Obstetrics-Gynecology and Perinatology Clinics of Etlik Zubeyde Hanim Women's Health Education and Training Hospital. Singleton pregnant women with late-onset FGR who were followed up in outpatient clinics or hospitalized and whose pregnancy resulted at our hospital were included in the study group (group I)...
March 27, 2024: Archives of Gynecology and Obstetrics
https://read.qxmd.com/read/38536442/a-phase-1-double-blinded-placebo-controlled-clinical-trial-to-evaluate-the-safety-and-immunogenicity-of-hev-239-hecolin%C3%A2-vaccine-in-healthy-us-adults
#19
JOURNAL ARTICLE
Carol M Kao, Christina A Rostad, Lauren E Nolan, Etza Peters, Jennifer Kleinhenz, Jacob D Sherman, Ashley Tippett, J Wai Kuo Shih, Inci Yildirim, Vivien Agbakoba, Tatiana Beresnev, Cassandra Ballou, Satoshi Kamidani, Vinit Karmali, Muktha Natrajan, Erin M Scherer, Nadine Rouphael, Evan J Anderson
INTRODUCTION: Establishing the safety and immunogenicity of a hepatitis E virus vaccine in multiple populations could facilitate broader access and prevent maternal and infant mortality. METHODS: We conducted a phase 1, randomized, double-blinded, placebo-controlled (4:1 vaccine: placebo) trial of 30 µg HEV-239 (Hecolin®, Xiamen Innovax Biotech Company Limited, China) administered intramuscularly in healthy US adults aged 18-45 years. Participants were vaccinated on days 1, 29, and 180...
March 27, 2024: Journal of Infectious Diseases
https://read.qxmd.com/read/38536215/infant-mortality-by-selected-maternal-characteristics-and-race-and-hispanic-origin-in-the-united-states-2019-2021
#20
JOURNAL ARTICLE
Danielle M Ely, Anne K Driscoll
Objectives- This report presents infant mortality rates for selected maternal characteristics (prepregnancy body mass index, cigarette smoking during pregnancy, receipt of Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) benefits during pregnancy, timing of prenatal care, and source of payment for delivery) for the five largest maternal race and Hispanic-origin groups in the United States for combined years 2019-2021. Methods-Descriptive tabulations based on data from the linked birth/infant death files for 2019-2021 are presented...
March 2024: National Vital Statistics Reports
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