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status asthmaticus pediatric

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https://www.readbyqxmd.com/read/27889372/-non-invasive-ventilation-in-children-do-we-need-more-evidence
#1
G Mortamet, G Emeriaud, P Jouvet, B Fauroux, S Essouri
Respiratory failure is the leading cause of hospital admissions in the pediatric intensive care unit (PICU) and is associated with significant morbidity and mortality. Mechanical ventilation, preferentially delivered by a non-invasive route (NIV), is currently the first-line treatment for respiratory failure since it is associated with a reduction in the intubation rate. This ventilatory support is increasingly used in the PICU, but its wider use contrasts with the paucity of studies in this field. This review aims to describe the main indications of NIV in acute settings: (i) bronchiolitis; (ii) postextubation respiratory failure; (iii) acute respiratory distress syndrome; (iv) pneumonia; (v) status asthmaticus; (vi) acute chest syndrome; (vii) left heart failure; (viii) exacerbation of chronic respiratory failure; (ix) upper airway obstruction and (x) end-of-life care...
November 23, 2016: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/27785078/anti-inflammatory-dosing-of-theophylline-in-the-treatment-of-status-asthmaticus-in-children
#2
Nemr S Eid, Adrian O'Hagan, Scott Bickel, Ronald Morton, Sarah Jacobson, John A Myers
BACKGROUND: Low-dose theophylline has been recognized for its ability to restore histone deacetylase-2 activity which leads to improved steroid responsiveness and thus improved clinical outcome. We retrospectively evaluated the effect of low-dose theophylline therapy in pediatric patients hospitalized for an acute asthma exacerbation as a proof of concept study. METHODS: We compared patients who received low-dose theophylline (5-7 mg/kg/day) in addition to current standard of care to patients who were treated with current standard of care alone...
2016: Journal of Asthma and Allergy
https://www.readbyqxmd.com/read/27670564/venovenous-extracorporeal-membrane-oxygenation-in-pediatric-respiratory-failure
#3
P Benson Ham, Brice Hwang, Linda J Wise, K Christian Walters, Walter L Pipkin, Charles G Howell, Jatinder Bhatia, Robyn Hatley
Conventional treatment of respiratory failure involves positive pressure ventilation that can worsen lung damage. Extracorporeal membrane oxygenation (ECMO) is typically used when conventional therapy fails. In this study, we evaluated the use of venovenous (VV)-ECMO for the treatment of severe pediatric respiratory failure at our institution. A retrospective analysis of pediatric patients (age 1-18) placed on ECMO in the last 15 years (1999-2014) by the pediatric surgery team for respiratory failure was performed...
September 2016: American Surgeon
https://www.readbyqxmd.com/read/27428241/general-anesthesia-exposure-in-early-life-reduces-the-risk-of-allergic-diseases-a-nationwide-population-based-cohort-study
#4
Ho-Chang Kuo, Ya-Ling Yang, Shu-Chen Ho, Mindy Ming-Huey Guo, Jyun-Hong Jiang, Ying-Hsien Huang
General anesthesia (GA) has been used for second line treatment strategy for status asthmaticus in pediatric patients. The association between GA in children and risk of followed-up allergic diseases is unclear. This study aims to assess the risk of allergic diseases after GA in children.We did a nationwide retrospective cohort study by analyzing data from the National Health Insurance Research Database (NHIRD) in Taiwan. The subsequent risks for allergic diseases, including asthma (ICD-9: 493.X), allergic rhinitis (AR; ICD-9 CM code 477...
July 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27292859/allocating-staff-intensive-therapies-in-pediatric-status-asthmaticus
#5
(no author information available yet)
No abstract text is available yet for this article.
July 2016: American Journal of Bioethics: AJOB
https://www.readbyqxmd.com/read/27012614/impact-of-obesity-on-clinical-outcomes-in-urban-children-hospitalized-for-status-asthmaticus
#6
Elena Aragona, Eussra El-Magbri, Justin Wang, Tessa Scheckelhoff, Trevor Scheckelhoff, Assata Hyacinthe, Suja Nair, Amina Khan, Gustavo Nino, Dinesh K Pillai
BACKGROUND AND OBJECTIVE: The prevalence of both childhood asthma and obesity remain at historically high levels and disproportionately affect urban children. Asthma is a common and costly cause for pediatric hospitalization. Our objective was to determine the effect of obesity on outcomes among urban children hospitalized with status asthmaticus. METHODS: A retrospective cohort study was performed by using billing system data and chart review to evaluate urban children admitted for asthma...
April 2016: Hospital Pediatrics
https://www.readbyqxmd.com/read/26761478/noninvasive-ventilation-in-status-asthmaticus-in-children-levels-of-evidence
#7
Paula de Souza Silva, Sérgio Saldanha Menna Barreto
OBJECTIVE: To evaluate the quality of available evidence to establish guidelines for the use of noninvasive ventilation for the management of status asthmaticus in children unresponsive to standard treatment. METHODS: Search, selection and analysis of all original articles on asthma and noninvasive ventilation in children, published until September 1, 2014 in all languages in the electronic databases PubMed, Web of Science, Cochrane Library, Scopus and SciELO, located using the search terms: "asthma", "status asthmaticus", "noninvasive ventilation", "Bronchospasm", "continuous positive airway pressure", "child", "infant", "pediatrics", "hypercapnia", "respiratory failure" and the keywords "BIPAP", "CPAP", "Bilevel", "acute asthma" and "near fatal asthma"...
October 2015: Revista Brasileira de Terapia Intensiva
https://www.readbyqxmd.com/read/26570951/1291-early-venovenous-ecmo-for-refractory-status-asthmaticus-in-a-pediatric-adolescent
#8
Dominick Figueroa, Jose Hernandez Rivera, Fernando Beltramo
No abstract text is available yet for this article.
December 2015: Critical Care Medicine
https://www.readbyqxmd.com/read/26380574/morphine-an-effective-abortive-therapy-for-pediatric-paroxysmal-sympathetic-hyperactivity-after-hypoxic-brain-injury
#9
Deborah S Raithel, Kirsten H Ohler, Isabel Porto, Alma R Bicknese, Donna M Kraus
Paroxysmal sympathetic hyperactivity (PSH) is a life-threatening condition characterized by hyperadrenergic activity and autonomic dysfunction. Also termed autonomic storms, PSH can occur after a variety of cerebral insults, most commonly traumatic brain injury. Limited pediatric literature is available, especially in patients with brain injury from hypoxia. No consensus exists for the terminology, diagnostic criteria, or treatment algorithm for PSH. Thus, the optimal management, including medication selection and dosing, remains unclear...
July 2015: Journal of Pediatric Pharmacology and Therapeutics: JPPT: the Official Journal of PPAG
https://www.readbyqxmd.com/read/26106203/an-asthma-protocol-improved-adherence-to-evidence-based-guidelines-for-pediatric-subjects-with-status-asthmaticus-in-the-emergency-department
#10
Andrew G Miller, Moira E Breslin, Leslie C Pineda, James W Fox
BACKGROUND: In our institution's pediatric emergency department, adherence to evidence-based asthma guidelines was noted to be suboptimal for patients with asthma exacerbations. We hypothesized that an evidence-based asthma protocol would improve time to treatment and adherence to National Institutes of Health guidelines for patients presenting to the emergency department with status asthmaticus. METHODS: Subjects at our institution were retrospectively identified through an electronic medical record search following institutional review board approval...
December 2015: Respiratory Care
https://www.readbyqxmd.com/read/25831031/cervical-lung-herniation-complicating-a-case-of-acute-asphyxial-asthma-in-a-child
#11
Melissa A Martchek, Benjamin E Padilla, Mark R Zonfrillo, Eron Y Friedlaender
The abrupt onset of respiratory failure secondary to asthma, known as acute asphyxial asthma (AAA) in adults, is uncommonly reported in children. Here, we report a case of a child with the acute onset of respiratory failure consistent with AAA complicated by the finding of a neck mass during resuscitation. This 11-year-old boy with a history of asthma initially presented in respiratory failure with altered mental status after the complaint of difficulty in breathing minutes before collapsing at home. Initially, his respiratory failure was thought to be secondary to status asthmaticus, and treatment was initiated accordingly...
April 2015: Pediatric Emergency Care
https://www.readbyqxmd.com/read/25738493/diastolic-hypotension-in-pediatric-patients-with-asthma-receiving-continuous-albuterol
#12
Sarah Wisecup, Shannan Eades, Syed Shahrukh Hashmi, Cheryl Samuels, Ricardo Alberto Mosquera
OBJECTIVES: Concerns have been raised regarding cardiac side effects of continuous high-dose albuterol nebulization in status asthmaticus management. Our study goal was to determine prevalence and potential risk factors for hypotension development during continuous albuterol administration in pediatric patients. METHODS: A retrospective cohort study was conducted at Children's Memorial Hermann Hospital from 1 January 2011 to 31 August 2012. A total of 152 patients admitted to pediatric intensive or intermediate care units who received continuous albuterol nebulization for management of status asthmaticus were analyzed...
September 2015: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/25580870/volatile-anesthetics-for-status-asthmaticus-in-pediatric-patients-a-comprehensive-review-and-case-series
#13
REVIEW
Sabrina Carrié, Thomas Anthony Anderson
Status asthmaticus is an acute, intractable asthma attack refractory to standard interventions that can lead to progressive respiratory failure. Successful management requires a fundamental understanding of the disease process, its clinical presentation, and proper evaluation. Treatment must be instituted early and is aimed at reversing the airway inflammation, bronchoconstriction, and hyper-reactivity that often lead to lower airway obstruction, impaired ventilation, and oxygenation. Most patients are effectively treated with standard therapy including beta2-adrenergic agonists and corticosteroids...
May 2015: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/25560428/effect-of-high-dose-continuous-albuterol-nebulization-on-clinical-variables-in-children-with-status-asthmaticus
#14
Suwannee Phumeetham, Thomas J Bahk, Shamel Abd-Allah, Mudit Mathur
OBJECTIVES: Continuous albuterol nebulization is generally administered at 2.5-20 mg/hr at most centers. We examined the effect of high-dose (75 or 150 mg/hr) albuterol on clinical variables in children with status asthmaticus. DESIGN: Retrospective analysis of inpatient medical records and prospectively collected computerized PICU respiratory therapy database. SETTING: Twenty-five-bed multidisciplinary PICU in a tertiary care children's hospital...
February 2015: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/25449960/childhood-obesity-and-in-hospital-asthma-resource-utilization
#15
Jessica Bettenhausen, Henry Puls, Mary Ann Queen, Christina Peacock, Stephanie Burrus, Christopher Miller, Ashley Daly, Jeffrey D Colvin
OBJECTIVE: To examine the relationship between pediatric obesity and inpatient length of stay (LOS), resource utilization, readmission rates, and total billed charges for in-hospital status asthmaticus. DESIGN/METHODS: We conducted a cross-sectional study of patients 5 to 17 years old hospitalized with status asthmaticus to 1 free-standing children's hospital system over 12 months. Only hospitalized patients initially treated in the hospital's emergency department were included to ensure all therapies/charges were examined...
March 2015: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/24714184/-development-and-effectiveness-of-a-tailored-education-program-for-caregivers-of-asthmatic-children
#16
RANDOMIZED CONTROLLED TRIAL
Misa Iio, Koji Takenaka, Masami Narita, Masaki Futamura, Mana Hamaguchi, Kanako Fukushima, Orie Yamano, Jun Haraguchi, Hirokazu Sakai, Akira Ishiguro, Yukihiro Ohya
BACKGROUND: We developed a tailored education program using a touch-screen computer for changing management behavior with asthmatic children and their caregivers. The purpose of this study was to examine the effect of the tailored education program. METHODS: Caregivers including children with asthma were recruited during visits to a national children's hospital and those whose month-long asthma condition on the JPAC (Japanese Pediatric Asthma Program) score was 14 and below were included...
February 2014: Arerugī, [Allergy]
https://www.readbyqxmd.com/read/24673123/relevance-of-chest-radiography-in-pediatric-inpatients-with-asthma
#17
Sridaran Narayanan, Terri Magruder, Susan Chu Walley, Tony Powers, Terry Craft Wall
INTRODUCTION: The goals of this study are to identify factors associated with ordering of chest radiographs (CXR's) in children hospitalized with acute asthma exacerbations and determine the overall clinical impact of these CXR's. METHODS: A retrospective study was performed with children ≥ 2 years of age admitted from our emergency department (ED) between 6/1/2011 and 5/31/2012 with a primary diagnosis of acute asthma exacerbation or status asthmaticus. Patients were excluded if they had been on antibiotics prior to the emergency visit, received continuous albuterol or intravenous magnesium during the hospitalization, or had another chronic disease affecting lung function...
September 2014: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/24639274/transient-intrapulmonary-shunting-in-a-patient-treated-with-%C3%AE-%C3%A2-adrenergic-agonists-for-status-asthmaticus
#18
Melissa L Bates, Joseph E Jacobson, Marlowe W Eldridge
Intrapulmonary arteriovenous anastomoses (IPAVs) are large-diameter pathways that directly connect the arterial and venous networks, bypassing the pulmonary capillaries. Ubiquitously present in healthy humans, these pathways are recruited in experimental conditions by exercise, hypoxia, and catecholamines and have been previously shown to be closed by hyperoxia. Whether they play a role in pulmonary pathophysiology is unknown. Here, we describe IPAV recruitment associated with hypoxemia and right-to-left shunt in a patient with status asthmaticus, treated with agonists of the B2-adrenergic pathway...
April 2014: Pediatrics
https://www.readbyqxmd.com/read/24515516/dexamethasone-for-acute-asthma-exacerbations-in-children-a-meta-analysis
#19
REVIEW
Grant E Keeney, Matthew P Gray, Andrea K Morrison, Michael N Levas, Elizabeth A Kessler, Garick D Hill, Marc H Gorelick, Jeffrey L Jackson
BACKGROUND AND OBJECTIVE: Dexamethasone has been proposed as an equivalent therapy to prednisone/prednisolone for acute asthma exacerbations in pediatric patients. Although multiple small trials exist, clear consensus data are lacking. This systematic review and meta-analysis aimed to determine whether intramuscular or oral dexamethasone is equivalent or superior to a 5-day course of oral prednisone or prednisolone. The primary outcome of interest was return visits or hospital readmissions...
March 2014: Pediatrics
https://www.readbyqxmd.com/read/24062374/quality-indicators-for-high-acuity-pediatric-conditions
#20
REVIEW
Antonia S Stang, Sharon E Straus, Jennifer Crotts, David W Johnson, Astrid Guttmann
OBJECTIVE: Identifying gaps in care and improving outcomes for severely ill children requires the development of evidence-based performance measures. We used a systematic process involving multiple stakeholders to identify and develop evidence-based quality indicators for high acuity pediatric conditions relevant to any emergency department (ED) setting where children are seen. METHODS: A prioritized list of clinical conditions was selected by an advisory panel...
October 2013: Pediatrics
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