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https://www.readbyqxmd.com/read/29036977/-safety-and-feasibility-of-sheathless-transfemoral-aortic-valve-implantation
#1
H J Pei, S Y Teng, T Luo, Y J Wu, Y J Yang, S B Qiao, B Xu, R L Gao
Objective: To investigate the safety and feasibility of sheathless transfemoral aortic valve replacement (TAVR). Methods: In this prospective study, we enrolled 23 patients with severe aortic stenosis (AS) who were inoperable or at high-risk for surgical aortic valve replacement operation in Fuwai hospital From September 2012 to June 2015. Multislice spiral CT and angiography of femoral artery showed that all patients had minimal femoral artery diameters (<6.5 mm) and severe calcification which was not suitable for transfemoral TAVR through sheath...
September 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/29036176/association-and-clinical-utility-of-nat2-in-the-prediction-of-isoniazid-induced-liver-injury-in-singaporean-patients
#2
Sze Ling Chan, Angeline Poh Gek Chua, Folefac Aminkeng, Cynthia Bin Eng Chee, Shengnan Jin, Marie Loh, Suay Hong Gan, Yee Tang Wang, Liam R Brunham
BACKGROUND AND AIMS: Isoniazid (INH) is part of the first-line-therapy for tuberculosis (TB) but can cause drug-induced liver injury (DILI). Several candidate single nucleotide polymorphisms (SNPs) have been previously identified but the clinical utility of these SNPs in the prediction of INH-DILI remains uncertain. The aim of this study was to assess the association between selected candidate SNPs and the risk of INH-DILI and to assess the clinical validity of associated variants in a Singaporean population...
2017: PloS One
https://www.readbyqxmd.com/read/29036173/pre-treatment-with-gnrha-or-ulipristal-acetate-prior-to-laparoscopic-and-laparotomic-myomectomy-a-systematic-review-and-meta-analysis
#3
Inge de Milliano, Moniek Twisk, Johannes C Ket, Judith A Huirne, Wouter J Hehenkamp
BACKGROUND: Myomectomy has potential risks of complications. To reduce these risks, medical pre-treatment can be applied to reduce fibroid size and thereby potentially decrease intra-operative blood loss, the need for blood transfusion and emergency hysterectomy. The aim of this systematic review and meta-analysis is to study the effectiveness of medical pre-treatment with Gonadotropin-releasing hormone agonists (GnRHa) or ulipristal acetate prior to laparoscopic or laparotomic myomectomy on intra-operative and post-operative outcomes...
2017: PloS One
https://www.readbyqxmd.com/read/29035701/does-sofa-predict-outcomes-better-than-sirs-in-brazilian-icu-patients-with-suspected-infection-a-retrospective-cohort-study
#4
Regis Goulart Rosa, Rafael Barberena Moraes, Thiago Costa Lisboa, Daniel Pretto Schunemann, Cassiano Teixeira
We compared the discriminatory capacity of the sequential organ failure assessment (SOFA) versus the systemic inflammatory response syndrome (SIRS) score for predicting ICU mortality, need for and length of mechanical ventilation (MV), ICU stay, and hospitalization in patients with suspected infection admitted to a mixed Brazilian ICU. We performed a retrospective analysis of a longitudinal ICU database from a tertiary hospital in Southern Brazil. Patients were categorized according to whether they met the criteria for sepsis according to SOFA (variation ≥2 points over the baseline clinical condition) and SIRS (SIRS score ≥2 points)...
October 13, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29035699/risk-factors-for-complications-of-intraoral-removal-of-submandibular-sialoliths
#5
Sung Hwa Dong, Seok Hyun Kim, Jeon Gang Doo, Ah Ra Jung, Young Chan Lee, Young-Gyu Eun
PURPOSE: Intraoral removal of submandibular sialoliths is a surgical technique for the treatment of sialolithiasis and is reported to have excellent outcomes. The aim of this study was to determine the risk factors leading to complications of this procedure. PATIENTS AND METHODS: The medical records of 200 patients who had undergone intraoral removal of sialoliths from January 2006 through June 2015 were retrospectively reviewed. A telephone survey was used to check postoperative symptoms...
September 21, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29035641/analysis-of-clinical-features-of-lipoblastoma-in-children
#6
Ji-Won Han, Hongbeom Kim, Joong Kee Youn, Chaeyoun Oh, Sung-Eun Jung, Kwi-Won Park, Seong-Cheol Lee, Hyun-Young Kim
OBJECTIVE: A lipoblastoma is pathologically benign but often recurs. Due to its rarity, studies are scarce. The purpose of this study was to investigate the clinical characteristics of lipoblastoma occurring in children and to detect any correlations with the expression of Ki-67. PARTICIPANTS: From 1998 to 2010, 33 patients were diagnosed with lipoblastoma at Seoul National University Children's Hospital. METHODS: Ki-67 immunohistochemistry staining of the tumor tissue was performed...
October 16, 2017: Pediatric Hematology and Oncology
https://www.readbyqxmd.com/read/29035459/level-of-platelet-distribution-width-and-outcome-prediction-in-patients-with-traumatic-brain-injury
#7
Biao Zhang, Jianjun Gu, Yizhen Qiu, Jin Zhao, Yi Song, Huojun Jiang, Aliang Ding, Xiaoqi Chen, Rongming Yu, Guofang Liu, Aihao Hu
BACKGROUND: This study examines the clinical utility of the level of increased platelet distribution width (PDW) as a predictor of outcome in patients with traumatic brain injury. METHODS: In this retrospective study, 120 patients with traumatic brain injury (TBI) were recruited. Age, gender, PDW, and Glasgow Coma Scale (GCS) scores were measured. These patients were divided into two groups based on their 30-day outcomes. Receiver operating curves (ROCs) were generated to identify predictors of 30-day mortality...
October 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/29035177/use-of-epidural-analgesia-as-an-adjunct-in-elective-abdominal-wall-reconstruction-a-review-of-4983-cases
#8
Efstathios Karamanos, Sophie Dream, Anthony Falvo, Nathan Schmoekel, Aamir Siddiqui
CONTEXT: Use of epidural analgesia in patients undergoing elective abdominal wall reconstruction is common. OBJECTIVE: To assess the impact of epidural analgesia in patients undergoing abdominal wall reconstruction. DESIGN: All patients who underwent elective ventral hernia repair from 2005 to 2014 were retrospectively identified. Patients were divided into two groups by the postoperative use of epidural analgesics as an adjunct analgesic method...
2017: Permanente Journal
https://www.readbyqxmd.com/read/29035134/hand-assisted-laparoscopic-versus-laparoscopic-nephrectomy-as-outpatient-procedures-a-prospective-randomized-study
#9
Nessn H Azawi, Tom Christensen, Claus Dahl, Lars Lund
OBJECTIVES: The aims of this study were to discuss the hand-assisted laparoscopic nephrectomy (HALNo) outpatient procedure and compare it to the transperitoneal laparoscopic nephrectomy (LNo) outpatient procedure. MATERIALS AND METHODS: A prospective, randomized study of 30 patients with renal tumor who were recruited between November 2014 and February 2016 was performed. The primary endpoint of the study was length of hospital stay (LOS). RESULTS: Fifteen patients received HALNo and 15 received LNo, with a male to female ratio of 2:1...
October 16, 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/29034562/canine-central-corneal-thickness-measurements-via-pentacam-hr-%C3%A2-optical-coherence-tomography-optovue-ivue-%C3%A2-and-high-resolution-ultrasound-biomicroscopy
#10
Allison E Wolfel, Samantha L Pederson, Allison M Cleymaet, Ann M Hess, Kate S Freeman
OBJECTIVE: To compare central corneal thickness (CCT) values in canine eyes using Pentacam-HR(®) Scheimpflug imaging (Pentacam), Optovue(®) iVue spectral-domain optical coherence tomography (SD-OCT), and high-resolution ultrasound biomicroscopy (UBM) and generate normative canine Pentacam CCT values. ANIMALS STUDIED: Twenty-four client-owned dogs (37 eyes) with nondiseased cornea(s) presenting to the Colorado State University Veterinary Teaching Hospital. PROCEDURES: Corneal images were acquired via Pentacam, SD-OCT, and UBM in the listed order...
October 15, 2017: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/29034236/prognostic-value-of-the-new-prostate-cancer-international-society-of-urological-pathology-grade-groups
#11
Anne Offermann, Silke Hohensteiner, Christiane Kuempers, Julika Ribbat-Idel, Felix Schneider, Finn Becker, Marie Christine Hupe, Stefan Duensing, Axel S Merseburger, Jutta Kirfel, Markus Reischl, Verena Lubczyk, Rainer Kuefer, Sven Perner
Gleason grading is the best independent predictor for prostate cancer (PCa) progression. Recently, a new PCa grading system has been introduced by the International Society of Urological Pathology (ISUP) and is recommended by the World Health Organization (WHO). Following studies observed more accurate and simplified grade stratification of the new system. Aim of this study was to compare the prognostic value of the new grade groups compared to the former Gleason Grading and to determine whether re-definition of Gleason Pattern 4 might reduce upgrading from prostate biopsy to radical prostatectomy (RP) specimen...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/29034090/pre-to-postoperative-coagulation-profile-of-307-patients-undergoing-oesophageal-resection-with-epidural-blockade-over-a-10-year-period-in-a-single-hospital-implications-for-the-risk-of-spinal-haematoma
#12
Owain Thomas, Emanuel Lybeck, Per Flisberg, Ulf Schött
BACKGROUND: Epidural anaesthesia and analgesia are indicated for oesophageal surgery. A rare but serious complication is spinal haematoma, which can occur on insertion, manipulation or withdrawal of catheters. Evidence and guidelines are vague regarding which tests are appropriate and how to interpret their results. We aimed to describe how routine coagulation test results change during oesophagectomy's perioperative course. METHODS: Following ethical approval, we retrospectively identified patients who had undergone oesophagectomy between 2002 and 2012...
2017: Perioperative Medicine
https://www.readbyqxmd.com/read/29033778/a-case-of-basaloid-squamous-cell-carcinoma-of-polypoid-type-in-the-esophagus
#13
Ki Hun Lee, Sang Jin Lee, Hak Soo Kim, Sung Eun Kim, Soo Yong Choi, Hyun Ju Lee, Suk Hun Ha, Kwang Hoon Oh, Dae-Woon Eom
Basaloid squamous cell carcinoma of the esophagus is very rare. Further, polypoid type of esophageal cancer is also rare. We have recently treated a case of basaloid squamous cell carcinoma which presented as a 1.3-cm esophageal polyp. A 48-year-old woman was referred to our hospital because of a polypoid mass at 36 cm distance from the upper incisor on endoscopic examination, and the result of the biopsy was basaloid squamous cell carcinoma. The patient underwent Ivor Lewis operation with lymph node dissection...
September 2017: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/29033610/a-pilot-randomized-controlled-clinical-trial-of-second-uterine-curettage-versus-usual-care-to-determine-the-effect-of-re-curettage-on-patients-need-for-chemotherapy-among-women-with-low-risk-nonmetastatic-gestational-trophoblastic-neoplasm-in-urmia-iran
#14
Haleh Ayatollahi, Zahra Yekta, Elnaz Afsari
OBJECTIVE: The objective of this study was to determine if second curettage was associated with a decreased need for the number of chemotherapy treatments compared to usual care. METHODS: A pilot randomized controlled clinical trial was designed at Motahhari Referral Hospital in 2014. Fifty-two patients with low risk, nonmetastatic gestational trophoblastic neoplasm were assigned randomly to two arms. The interventional arm included a repeat uterine curettage, and the control group received standard care (chemotherapy)...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/29033572/role-of-heart-rate-variability-in-preoperative-assessment-of-physiological-reserves-in-patients-undergoing-major-abdominal-surgery
#15
Petr Reimer, Jan Máca, Pavel Szturz, Ondřej Jor, Roman Kula, Pavel Ševčík, Michal Burda, Milan Adamus
BACKGROUND: Major abdominal surgery (MAS) is associated with increased morbidity and mortality. The main objective of our study was to evaluate the predictive value of heart-rate variability (HRV) concerning development of postoperative complications in patients undergoing MAS. The secondary objectives were to identify the relationship of HRV and use of vasoactive drugs during anesthesia, intensive care unit length of stay (ICU-LOS), and hospital length of stay (H-LOS). PATIENTS AND METHODS: Sixty-five patients scheduled for elective MAS were enrolled in a prospective, single-center, observational study...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29033559/pressure-injuries-in-elderly-with-acute-myocardial-infarction
#16
Klara Komici, Dino F Vitale, Dario Leosco, Angela Mancini, Graziamaria Corbi, Leonardo Bencivenga, Alessandro Mezzani, Bruno Trimarco, Carmine Morisco, Nicola Ferrara, Giuseppe Rengo
OBJECTIVES: To assess pressure injury (PI) incidence among patients hospitalized for acute myocardial infarction (AMI) in an intensive coronary care unit (ICCU) and to detect the impact of specific risk factors on the development of PI in this clinical setting. PATIENTS AND METHODS: Prospective cohort study in ICCU setting. Patients admitted for AMI: patients mean age 67.5±11.5 years (n=165). Norton Scale, Mini Nutritional Assessment (MNA), demographic, clinical and biochemical data collected at the time of ICCU admission have been tested in a logistic model to assess the odds ratios (ORs) of PI risk development...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29033510/admission-value-of-serum-cathepsin-d-level-can-be-useful-for-predicting-in-hospital-mortality-in-patients-with-nstemi
#17
Harun Kundi, Ahmet Balun, Hulya Cicekcioglu, Mustafa Cetin, Emrullah Kiziltunc, Canan Topcuoglu, Muhammed Fevzi Kilinckaya, Ender Ornek
BACKGROUND: We aimed to investigate the association of serum cathepsin D levels with in-hospital mortality and Syntax scores (SXscore) in non-ST elevation myocardial infarction (NSTEMI) patients. METHODS: A total of 88 patients were included in the study. The patients were divided into two groups: those with in-hospital mortality (-), and those with in-hospital mortality (+). The receiver operating characteristics curve was used to show the sensitivity and specificity of serum cathepsin D levels, and the optimal cut-off value for predicting in-hospital mortality and high SXscore...
July 2017: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/29033375/intraprocedural-arterial-perforation-during-neuroendovascular-therapy-preliminary-result-of-a-dual-trained-endovascular-neurosurgeon-in-the-neurosurgical-hybrid-operating-room
#18
Yuang-Seng Tsuei, Chih-Hsiang Liao, Chung-Hsin Lee, Yea-Jiuan Liang, Wen-Hsien Chen, Shun-Fa Yang
BACKGROUND: Intraprocedural arterial perforation (IPAP) is a potentially dismal complication of neuroendovascular therapy with high mortality and morbidity rates. The management of IPAP with the techniques described has been well established, but rescue results from the dual-trained endovascular neurosurgeon in the neurosurgical hybrid operating room (OR) are rarely reported. Here, we report five cases of successful rescue of IPAP in the neurosurgical hybrid OR and compare them with other series...
October 12, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/29033336/open-abdomen-therapy-with-vacuum-and-mesh-mediated-fascial-traction-after-aortic-repair-an-international-multicentre-study
#19
Stefan Acosta, Arne Seternes, Maarit Venermo, Leena Vikatmaa, Karl Sörelius, Anders Wanhainen, Mats Svensson, Khatereh Djavani, Martin Björck
OBJECTIVES: Open abdomen therapy may be necessary to prevent or treat abdominal compartment syndrome (ACS). The aim of the study was to analyse the primary delayed fascial closure (PDFC) rate and complications after open abdomen therapy with vacuum and mesh mediated fascial traction (VACM) after aortic repair and to compare outcomes between those treated with open abdomen after primary versus secondary operation. METHODS: This was a retrospective cohort, multicentre study in Sweden, Finland, and Norway, including consecutive patients treated with open abdomen and VACM after aortic repair at six vascular centres in 2006-2015...
October 12, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29033271/surgical-education-module-improves-operative-proficiency-in-endoscopic-carpal-tunnel-release-a-blinded-randomized-controlled-trial-of-trainees
#20
Steve J Kempton, A Neil Salyapongse, Jacqueline S Israel, Benjamin A Mandel
OBJECTIVE: The purpose of this study is to evaluate whether an interactive endoscopic carpal tunnel release (ECTR) surgical education module can improve knowledge of surgical indications and improve procedural competency. DESIGN: An ECTR education module was developed and trainees at various level of training were enrolled and randomized to surgical module and nonmodule (control) groups. Subjects were instructed that they would be the primary surgeon performing an ECTR...
October 12, 2017: Journal of Surgical Education
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