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https://www.readbyqxmd.com/read/29677642/diagnostic-value-of-18-f-fluordesoxyglucose-positron-emission-tomography-for-patients-with-brain-metastasis-from-unknown-primary-site
#1
Fabian Wolpert, Michael Weller, Anna Sophie Berghoff, Elisabeth Rushing, Lisa Michaela Füreder, Gregory Petyt, Henning Leske, Nicolaus Andratschke, Luca Regli, Marian Christoph Neidert, Roger Stupp, Rolf Stahel, Reinhard Dummer, Thomas Frauenfelder, Patrick Roth, Nicolas Reyns, Philipp Antonio Kaufmann, Matthias Preusser, Emilie Le Rhun
BACKGROUND: In 30% of patients with brain metastasis (BM), neurological symptoms are the first clinical manifestation of systemic malignancy, referred to as BM from cancer of unknown primary site (BM-CUPS). Here, we define the diagnostic value of 18 F-fluordesoxyglucose positron emission tomography (FDG-PET/CT) in the workup of BM-CUPS. METHODS: We screened 565 patients operated for BM at the University Hospital Zurich and identified 64 patients with BM-CUPS with data on both FDG-PET/CT and contrast-enhanced chest/abdomen computed tomography (CT) available at BM diagnosis...
April 17, 2018: European Journal of Cancer
https://www.readbyqxmd.com/read/29677384/risk-factors-and-long-term-outcomes-of-pediatric-liver-transplant-recipients-with-chronic-high-epstein-barr-virus-loads
#2
Hideya Kamei, Yoshinori Ito, Junichi Kawada, Satoshi Ogiso, Yasuharu Onishi, Masahiko Komagome, Nobuhiko Kurata, Yasuhiro Ogura
BACKGROUND: Serial monitoring of Epstein-Barr virus (EBV) reveals that certain pediatric liver transplant (LT) recipients exhibit high EBV loads for long periods. We investigated the incidence and risk factors of chronic high EBV (CHEBV) loads (continuous EBV DNA >10000 IU/mL of whole blood for ≥6 months) and long-term outcomes. METHODS: This single center, retrospective observational study investigated pediatric LT recipients who survived ≥6 months. We quantitated EBV DNA weekly during hospitalization and subsequently every 4 or 6 weeks at the outpatient clinic...
April 20, 2018: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/29677217/optimisation-of-three-dimensional-lower-jaw-resection-margin-planning-using-a-novel-black-bone-magnetic-resonance-imaging-protocol
#3
Astrid M Hoving, Joep Kraeima, Rutger H Schepers, Hildebrand Dijkstra, Jan Hendrik Potze, Bart Dorgelo, Max J H Witjes
BACKGROUND: MRI is the optimal method for sensitive detection of tumour tissue and pre-operative staging in oral cancer. When jawbone resections are necessary, the current standard of care for oral tumour surgery in our hospital is 3D virtual planning from CT data. 3D printed jawbone cutting guides are designed from the CT data. The tumour margins are difficult to visualise on CT, whereas they are clearly visible on MRI scans. The aim of this study was to change the conventional CT-based workflow by developing a method for 3D MRI-based lower jaw models...
2018: PloS One
https://www.readbyqxmd.com/read/29677082/artificial-intelligence-can-predict-daily-trauma-volume-and-average-acuity
#4
David P Stonko, Bradley M Dennis, Richard D Betzold, Allan B Peetz, Oliver L Gunter, Oscar D Guillamondegui
INTRODUCTION: The goal of this study was to integrate temporal and weather data in order to create an artificial neural network (ANN) to predict trauma volume, the number of emergent operative cases, and average daily acuity at a level 1 trauma center. METHODS: Trauma admission data from TRACS and weather data from the National Oceanic and Atmospheric Administration (NOAA) was collected for all adult trauma patients from July 2013-June 2016. The ANN was constructed using temporal (time, day of week), and weather factors (daily high, active precipitation) to predict four points of daily trauma activity: number of traumas, number of penetrating traumas, average ISS, and number of immediate OR cases per day...
April 19, 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29676943/impact-of-preoperative-thrombocytopenia-on-the-outcome-after-coronary-artery-bypass-grafting
#5
Wail Nammas, Magnus Dalén, Stefano Rosato, Riccardo Gherli, Daniel Reichart, Giuseppe Gatti, Francesco Onorati, Giuseppe Faggian, Marisa De Feo, Ciro Bancone, Sidney Chocron, Sorosh Khodabandeh, Giuseppe Santarpino, Antonino S Rubino, Daniele Maselli, Saverio Nardella, Antonio Salsano, Tiziano Gherli, Francesco Nicolini, Marco Zanobini, Matteo Saccocci, Karl Bounader, Paola D'Errigo, Tuomas Kiviniemi, Eeva-Maija Kinnunen, Andrea Perrotti, Juhani Airaksinen, Giovanni Mariscalco, Vito G Ruggieri, Fausto Biancari
The impact of thrombocytopenia on postoperative bleeding and other major adverse events after cardiac surgery is unclear. This issue was investigated in a series of patients who underwent isolated coronary artery bypass grafting (CABG) from the prospective, multicenter E-CABG registry. Preoperative thrombocytopenia was defined as preoperative platelet count <150 × 109 /L and it was considered moderate-severe when preoperative platelet count was <100 × 109 /L. Multilevel mixed-effects regression analysis was performed to adjust the effect of thrombocytopenia on outcomes for baseline and operative covariates as well as for interinstitutional differences in patient-blood management...
April 20, 2018: Platelets
https://www.readbyqxmd.com/read/29676694/keyhole-strategy-aiming-at-minimizing-hospital-stay-for-surgical-clipping-of-unruptured-middle-cerebral-artery-aneurysms
#6
Kentaro Mori, Kojiro Wada, Naoki Otani, Arata Tomiyama, Terushige Toyooka, Satoru Takeuchi, Takuji Yamamoto, Yasuaki Nakao, Hajime Arai
OBJECTIVE Aneurysms of the middle cerebral artery (MCA) are still most often treated by clipping through standard craniotomy, but a longer hospital stay is one of the main drawbacks of this treatment. The authors developed a pterional keyhole clipping strategy for unruptured MCA aneurysms with the intention of minimizing hospital stay. In this paper, they report on their experience with this approach and analyze the long-term neurological and radiological outcomes. METHODS A total of 160 relatively small unruptured MCA aneurysms (mean 6...
April 20, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29676340/progesterone-receptor-expression-and-ki-67-labelling-index-of-meningiomas-in-the-lagos-university-teaching-hospital
#7
Nzechukwu Zimudo Ikeri, Charles Chidozie Anunobi, Olufemi B Bankole
Background: Meningioma in Nigeria has been poorly studied. Its location within the intracranial cavity is associated with significant morbidity and mortality. Even when completely excised, it has a tendency to recur and this is associated with repeat operations and shortened survival. The World Health Organization (WHO) grade, progesterone receptor (PR) expression and Ki-67 index are predictive for recurrence and are, therefore, useful for individualised management. The aim of this study was therefore to determine the PR expression and Ki-67 index of meningiomas received in our institution...
January 2018: Nigerian Postgraduate Medical Journal
https://www.readbyqxmd.com/read/29676289/natural-history-and-outcome-of-inflammatory-bowel-diseases-in-children-in-saudi-arabia-a-single-center-experience
#8
Khalid M Alreheili, Khalid A Alsaleem, Ali I Almehaidib
Background/Aim: Inflammatory bowel disease (IBD) is a chronic gastrointestinal disorder which includes ulcerative colitis (UC), Crohn's disease (CD), and indeterminate colitis (IC). The natural history of pediatric IBDs is poorly understood and generally unpredictable. We aim to study the natural history of IBD in Saudi children including the extraintestinal manifestations, changes in diagnosis, disease behavior, medical management, and surgical outcome. Patients and Methods: A retrospective review of all the charts of children less than 14 years of age who were diagnosed as IBD and followed up in King Faisal Specialist Hospital and Research Center (KFSH and RC) from January 2001 to December 2011 was performed...
April 18, 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/29676053/increasing-success-in-outpatient-laparoscopic-cholecystectomy-by-an-optimal-clinical-pathway
#9
Tristan Greilsamer, François Orion, Fabrice Denimal, Benoît De Kerviler, Marc-Henri Jean, Jérôme Dimet, Michel Comy, Emeric Abet
BACKGROUND: The objective of this study was to evaluate the impact of more convincing and reassuring remarks from the surgeon in the preoperative consult associated with a dedicated outpatient facility to increase our rate of success in outpatient laparoscopic cholecystectomy. METHODS: A one-centre prospective clinical study was conducted between February 2013 and May 2015. During the first time period (February 2013-March 2014), patients were hospitalized in conventional care unit and given the possibility to choose an outpatient procedure...
April 19, 2018: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29675898/implementation-of-the-who-surgical-safety-checklist-at-a-teaching-hospital-in-india-and-evaluation-of-the-effects-on-perioperative-complications
#10
Raghavendra Shankar
BACKGROUND: The WHO Surgical Safety Checklist was developed to help operating teams reduce the occurrence of patient harm. The Checklist is a simple, practical tool that any surgical team in the world can use to ensure that the preoperative, intraoperative, and postoperative steps that have been shown to benefit patients are undertaken in a timely and efficient way. METHODS: This study was carried out at Rajarajeswari Medical College Hospital, Bangalore, India, to study the effects of the WHO Surgical Safety Checklist on mortality and morbidity in surgical patients, to identify the potential problems in the long-term implementation of the same, and to document the complications in patients undergoing a major surgery during the study period...
April 20, 2018: International Journal of Health Planning and Management
https://www.readbyqxmd.com/read/29675867/patient-perspectives-of-cataract-surgery-protocol-and-baseline-findings-of-a-cohort-study
#11
Vu Quang Do, Peter McCluskey, Anna Palagyi, Andrew White, Fiona J Stapleton, Nicole Carnt, Lisa Keay
BACKGROUND: Patient-reported outcome measures (PROMs) are becoming increasingly recognised as a key component in assessing the relative effectiveness of cataract surgery. This manuscript presents the protocol methodology and baseline characteristics of a prospective cohort study investigating patient-centred predictors of cataract surgery outcomes. METHODS: Patients with bilateral cataract (aged ≥ 50 years) scheduled for their first eye cataract surgery were recruited at four public hospitals and three private ophthalmology clinics in Sydney, Australia...
April 19, 2018: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/29675629/-geriatric-trauma-center-dgu%C3%A2-evaluation-of-clinical-and-economic-parameters-a-pilot-study-in-a-german-university-hospital
#12
M Knobe, B Böttcher, M Coburn, T Friess, L C Bollheimer, H J Heppner, C J Werner, J-P Bach, M Wollgarten, S Poßelt, C Bliemel, B Bücking
BACKGROUND: Previous studies on orthogeriatric models of care suggest that there is substantial variability in how geriatric care is integrated in the patient management and the necessary intensity of geriatric involvement is questionable. OBJECTIVE: The aim of the current prospective cohort study was the clinical and economic evaluation of fragility fracture treatment pathways before and after the implementation of a geriatric trauma center in conformity with the guidelines of the German Trauma Society (DGU)...
April 19, 2018: Der Unfallchirurg
https://www.readbyqxmd.com/read/29675320/tissue-intrinsic-fluorescence-recovering-by-an-empirical-approach-based-on-the-pso-algorithm-and-its-application-in-type-2-diabetes-screening
#13
Yuanzhi Zhang, Huayi Hou, Yang Zhang, Yikun Wang, Ling Zhu, Meili Dong, Yong Liu
In order to reduce the influence of scattering and absorption on tissue fluorescence spectra, after tissue fluorescence and diffuse reflectance in different tissue optical properties were simulated by the Monte Carlo method, a tissue intrinsic fluorescence recovering algorithm making use of diffuse reflectance spectrum was developed. The empirical parameters in the tissue intrinsic fluorescence recovering algorithm were coded as a particle in the solution domain, the classification performance was defined as the fitness, and then a particle swarm optimization (PSO) algorithm was established for empirical parameters optimization...
April 1, 2018: Biomedical Optics Express
https://www.readbyqxmd.com/read/29675068/cerebellar-mutism-syndrome-following-midline-posterior-fossa-tumor-resection-in-children-an-institutional-experience
#14
Nand Kishore Gora, Ashok Gupta, Virendra Deo Sinha
Aim: Cerebellar mutism (CM) syndrome is a well-known and annoying complication of posterior fossa surgery in the pediatric age group. Risk factors such as the type of tumor, size, involvement of posterior fossa structures and hydrocephalus, and postoperative cerebellar swelling for CM were investigated in this study. Materials and Methods: A consecutive series of 33 children with midline posterior fossa tumors were operated at the SMS Medical College and Hospital, Department of Neurosurgery, Jaipur India, between September 2015 and December 2016...
October 2017: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/29674363/study-protocol-on-criterion-validation-of-edinburgh-postnatal-depression-scale-epds-patient-health-questionnaire-phq-9-and-centre-for-epidemiological-studies-depression-ces-d-screening-tools-among-rural-postnatal-women-a-cross-sectional-study
#15
James January, Moses John Chimbari
BACKGROUND: Screening women for postnatal depression (PND) provides an opportunity to reach undetected cases and enhance pregnancy outcomes. In Zimbabwe, no validation of depression screening tools has been done on postnatal women in rural settings. OBJECTIVES: This study aims to determine criterion validity of the Edinburgh Postnatal Depression Scale (EPDS), the Patient Health Questionnaire (PHQ-9) and the Center for Epidemiological Studies-Depression (CES-D) scale using the Diagnostic and Statistical Manual for Mental Disorders (DSM-5) criteria as the reference standard...
April 19, 2018: BMJ Open
https://www.readbyqxmd.com/read/29673881/long-term-outcome-in-extracranial-intracranial-bypass-surgery-for-severe-steno-occlusive-disease-of-intracranial-internal-carotid-or-middle-cerebral-artery
#16
Kok Ann Colin Teo, Tseng Tsai Yeo, Vijay K Sharma
OBJECTIVES: We report the long-term outcome and rates of recurrent cerebral ischemic events in our cohort of carefully selected patients after STA-MCA bypass for severe steno-occlusive disease of intracranial ICA or MCA with exhausted cerebral vasodilatory reserve. PATIENTS AND METHODS: In this retrospective study, we reviewed the hospital records for all patients who underwent direct superficial temporal artery-middle cerebral artery bypass surgery at our institution from January 2010 to August 2017...
April 3, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29673691/laparoscopic-inguinal-ligament-suspension-with-uterine-preservation-for-pelvic-organ-prolapse-a-retrospective-cohort-study
#17
Chunbo Li, Huimin Shu, Zhiyuan Dai
OBJECTIVE: To introduce an alternative surgical technique of laparoscopic inguinal ligament suspension (LILS) with uterine preservation and evaluate its efficacy and safety for patients with severe pelvic organ prolapse (POP). METHODS: Between June 2014 and December 2015, 35 patients with symptomatic stage III or IV were treated by LILS with uterine preservation. The perioperative parameters including surgical time, blood loss, hospital stay and complications were recorded...
April 16, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29673673/the-application-of-uterine-wall-local-resection-and-reconstruction-to-preserve-the-uterus-for-the-management-of-morbidly-adherent-placenta-case-series
#18
Xianlan Zhao, Ya Tao, Yingying Du, Lei Zhao, Cai Liu, Yan Zhou, Peng Wei
OBJECTIVE: We aimed to evaluate our experience with the application of uterine wall local resection and reconstruction to preserve the uterus in patients with morbidly adherent placenta. MATERIALS AND METHODS: In a retrospective study, data from patients with morbidly adherent placenta who delivered by cesarean section between January 1, 2013 and May 31, 2016 were analyzed. Prophylactic abdominal aorta balloon occlusion and tourniquet were used to prevent massive hemorrhage in all 62 cases, followed by uterine wall local resection and reconstruction to preserve the uterus...
April 2018: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29673604/concurrence-of-big-data-analytics-and-healthcare-a-systematic-review
#19
REVIEW
Nishita Mehta, Anil Pandit
BACKGROUND: The application of Big Data analytics in healthcare has immense potential for improving the quality of care, reducing waste and error, and reducing the cost of care. PURPOSE: This systematic review of literature aims to determine the scope of Big Data analytics in healthcare including its applications and challenges in its adoption in healthcare. It also intends to identify the strategies to overcome the challenges. DATA SOURCES: A systematic search of the articles was carried out on five major scientific databases: ScienceDirect, PubMed, Emerald, IEEE Xplore and Taylor & Francis...
June 2018: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29673564/factors-affecting-the-efficacy-and-safety-of-aminophylline-in-treatment-of-apnea-of-prematurity-in-neonatal-intensive-care-unit
#20
Chaohui Ye, Caiyun Miao, Li Yu, Zhuoya Dong, Jie Zhang, Yingying Mao, Xiaodong Lu, Qin Lyu
BACKGROUND: The factors affecting the safety and efficacy of aminophylline use in the treatment of apnea of prematurity (AOP) in the neonatal intensive care unit (NICU) are not clear. In this study, we aimed to evaluate the potential factors affecting the efficacy and safety of aminophylline in AOP treatment at standard doses and to determine appropriate patients for this therapy. METHODS: Over a 3-year period (January 2012 to December 2014), the medical records of 206 preterm infants with apnea who were admitted to the NICU of our hospital to receive aminophylline infusions were retrospectively reviewed...
March 30, 2018: Pediatrics and Neonatology
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