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https://www.readbyqxmd.com/read/28917256/postoperative-stereotactic-body-radiotherapy-for-spinal-metastases
#1
Majed Alghamdi, Chia-Lin Tseng, Sten Myrehaug, Pejman Maralani, Chris Heyn, Hany Soliman, Young Lee, Mark Ruschin, Leodante Da Costa, Victor Yang, Mikki Campbell, Arjun Sahgal
Spine is a common site of metastases in cancer patients. Spine surgery is indicated for select patients, typically those with mechanical instability and/or malignant epidural spinal cord (or cauda equina) compression. Although post-operative conventional palliative external beam radiation therapy has been the standard of care, technical improvements in radiation planning and image-guided radiotherapy have allowed for the application of stereotactic body radiotherapy (SBRT) to the spine. Spine SBRT is intended to ablate residual tumor and optimize local control by delivering several fold greater biologically effective doses...
September 2017: Chinese Clinical Oncology
https://www.readbyqxmd.com/read/28913694/emergency-neurological-life-support-traumatic-spine-injury
#2
Deborah M Stein, William A Knight
Traumatic spine injuries (TSIs) carry significantly high risks of morbidity, mortality, and exorbitant health care costs from associated medical needs following injury. For these reasons, TSI was chosen as an ENLS protocol. This article offers a comprehensive review on the management of spinal column injuries using the best available evidence. Though the review focuses primarily on cervical spinal column injuries, thoracolumbar injuries are briefly discussed as well. The initial emergency department (ED) clinical evaluation of possible spinal fractures and cord injuries, along with the definitive early management of confirmed injuries, are also covered...
September 14, 2017: Neurocritical Care
https://www.readbyqxmd.com/read/28913395/simultaneous-bilateral-total-hip-arthroplasty-in-morquio-syndrome
#3
Imran Ilyas, Syed Kashif, Samar Rabbani, Husam A Alrumaih
A 16-year-old girl who had Morquio syndrome presented with severe bilateral hip pain and limited mobility because of bilateral hip osteoarthritis and fixed flexion deformities. She was wheelchair bound for the previous 6 months. Cervical spine flexion-extension views showed mild subluxation (<3 mm), and there was thoracolumbar spine kyphosis. Magnetic resonance imaging of the cervical and thoracolumbar spine showed hypoplasia of the odontoid and vertebral bodies, but no spinal cord compression. Bilateral cemented total hip arthroplasty was performed through a posterior approach under general anesthesia with fiberoptic intubation...
September 2017: Arthroplasty Today
https://www.readbyqxmd.com/read/28904585/is-it-the-monster-teratoma-or-simply-meningomyelocele-our-experience-of-histological-surprise
#4
Suyash Singh, Jayesh Sardhara, Pradeep Sharma, Arun Kumar Srivastava, Kuntal Kanti Das, Kamlesh S Bhaisora, Anant Mehrotra, Awadhesh Kumar Jaiswal, Sanjay Behari, Raj Kumar
Teratomas are one of the most common tumors in newborn with excellent prognosis arises from totipotent primordial germ cells harboring two or three germ cell layers. The tumor has been titled "Great masquerade." The teratomas of sacrococcygeal region present with lower limb weakness, urinary or bowel obstruction, and swelling at lower back or intrauterine mass in ultrasound or complicated delivery. A 2-month-old male child presented with complaints of swelling over lumbosacral region with discharging punctum since birth...
April 2017: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/28904574/multicentric-chordoma-in-a-child
#5
Shighakolli Ramesh, Raju Subodh, Srinadh Boppana, Erukkambattu Jayashankar
Chordomas are primary malignant bone tumors that arise in the axial skeleton, believed to originate from remnants of embryologic notochordal cell rests. Multicentric origin of chordoma is extremely rare. To our literature search, we found only three cases of multicentric chordoma in adults. We report a first case of multicentric chordoma in pediatric age group. A 14-month-old child presented with torticolis and left upper limb monoparesis, imaging showed expansile bony destructive lesion in clivus and dorsal spine simultaneously...
April 2017: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/28904564/the-role-of-pre-reduction-mri-in-the-management-of-complex-cervical-spine-fracture-dislocations-an-ongoing-controversy
#6
Sergiu Botolin, Todd F VanderHeiden, Ernest E Moore, Herbert Fried, Philip F Stahel
BACKGROUND: Cervical spine fracture-dislocations in neurologically intact patients represent a surgical challenge due to the risk of inflicting iatrogenic spinal cord compression by closed reduction maneuvers. The use of MRI for early advanced imaging in these injuries remains controversially debated. CASE PRESENTATION: A 54-year old man sustained a fall over the handlebars of his racing bicycle. The helmeted patient sustained a fall on his head which resulted in a hyperflexion injury of the neck...
2017: Patient Safety in Surgery
https://www.readbyqxmd.com/read/28902102/post-traumatic-spinal-hygroma-causing-cord-compression-in-type-iii-odontoid-fracture-with-vertical-atlantoaxial-instability
#7
Salvatore Russo, Antonio Belli, Andy Eynon, Ali Nader-Sepahi
STUDY DESIGN: Case report. OBJECTIVE: To report the first case in the literature of a traumatic cervical spine subdural cerebrospinal fluid (CSF) collection (hygroma) under tension causing cord compression. We suggest etiopathogenesis and modality of treatment. SUMMARY OF BACKGROUND DATA: Hygromas are subdural cranial CSF collection. A literature review showed no previous published case of post-traumatic spinal hygroma. This was a potential life-threatening sequelae of a high cervical injury that warranted early diagnosis and emergency treatment...
September 15, 2017: Spine
https://www.readbyqxmd.com/read/28893697/incidence-of-postoperative-hematomas-requiring-surgical-treatment-in-neurosurgery-a-retrospective-observational-study
#8
Kadri Lillemäe, Johanna Järviö, Marja Kaarina Silvasti-Lundell, Jussi Antinheimo, Juha Hernesniemi, Tomi Tapio Niemi
OBJECTIVE: We aimed to characterize the occurrence of postoperative hematoma (POH) after neurosurgery overall and according to procedure type, and describe the prevalence of possible confounders. METHODS: Patient data between 2010 and 2012 at the Department of Neurosurgery in Helsinki University Hospital were retrospectively analyzed. Data search was performed according to the type of surgery including craniotomies; shunt procedures, spine surgery and spinal cord stimulators (SCS) implantation...
September 8, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28891440/a-systematic-review-of-mesenchymal-stem-cells-in-spinal-cord-injury-intervertebral-disc-repair-and-spinal-fusion
#9
Shujhat Khan, Pouya Mafi, Reza Mafi, Wasim Khan
Spinal surgery presents a challenge for both neurosurgery and orthopaedic surgery. Due to the heterogeneous differentiation potential of mesenchymal stem cells, there is much interest in the treatment of spine surgery. Animal and human trials focussing on the efficacy of mesenchymal stem cells in spinal cord injury, spine fusion and disc degeneration were included in this systematic review. Published articles up to January 2016 from MEDLINE, PubMed and Ovid were used by searching for specific terms. Of the 2595 articles found, 53 met the selection criteria and were included for analysis (16 on spinal cord injury, 28 on intervertebral disc repair and 9 on spinal fusion)...
September 7, 2017: Current Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28889042/marginal-en-bloc-resection-of-c2-3-chordoma-with-bilateral-vertebral-artery-preservation-and-mesh-cage-reconstruction-with-review-of-previously-published-cases
#10
Steven O Tenny, Landon D Ehlers, J Will Robbins, Christopher C Gillis
BACKGROUND: Chordomas arise from remnants of the notocord and occur throughout the neuroaxis. En bloc resection of chordomas can prove especially challenging in the upper cervical spine secondary to the unique structural anatomy and intimate relationship to the vertebral arteries and spinal cord. CASE DESCRIPTION: We describe the resection of a C2-3 chordoma in a 55 year old female in two stage fashion with preservation of the vertebral arteries. First a posterior instrumented fusion and removal of the posterior elements was performed, followed by an anterior transmandibular en bloc resection with cage reconstruction with kick-plate support achievable with off-the-shelf products...
September 6, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28888674/geographical-variations-in-clinical-presentation-and-outcomes-of-decompressive-surgery-in-patients-with-symptomatic-degenerative-cervical-myelopathy-analysis-of-a-prospective-international-multicenter-cohort-study-of-757-patients
#11
Michael G Fehlings, Branko Kopjar, Ahmed Ibrahim, Lindsay A Tetreault, Paul M Arnold, Helton Defino, Shashank Sharad Kale, S Tim Yoon, Giuseppe M Barbagallo, Ronald H M Bartels, Qiang Zhou, Alexander R Vaccaro, Mehmet Zileli, Gamaliel Tan, Yasutsugu Yukawa, Darrel S Brodke, Christopher I Shaffrey, Osmar Santos de Moraes, Eric J Woodard, Massimo Scerrati, Masato Tanaka, Tomoaki Toyone, Rick C Sasso, Michael E Janssen, Ziya L Gokaslan, Manuel Alvarado, Ciaran Bolger, Christopher M Bono, Mark B Dekutoski
BACKGROUND CONTEXT: Degenerative cervical myelopathy (DCM) is a progressive degenerative spine disease and the most common cause of spinal cord impairment in adults worldwide. There is a paucity of studies reporting on regional variations in demographics, clinical presentation, disease causation and surgical effectiveness. PURPOSE: To evaluate differences in demographics, causative pathology, management strategies, surgical outcomes, length of hospital stay and complications across four geographic regions...
September 6, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28887080/a-rare-case-of-metastatic-extramammary-paget-disease-of-the-spine-and-review-of-the-literature
#12
A Karim Ahmed, C Rory Goodwin, Nancy Abu-Bonsrah, Doreen Nguyen, Daniel M Sciubba
Extramammary Paget disease is an intraepithelial neoplasm affecting cells rich in apocrine glands-often located in the vulvar, scrotal, or perianal region. It typically affects older patients, between the ages of 50 and 80years old, and is most often limited to the epidermis. A 47-year-old Asian male first presented with enlargement of the right inguinal lymph node. A subsequent biopsy revealed extrammamary Paget disease of the scrotum. The patient eventually developed significant worsening back pain with bilateral lower extremity numbness and weakness three months later...
September 5, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28885289/mesenchymal-stem-cell-levels-of-human-spinal-tissues
#13
Liam Harris, C Thomas Vangsness
STUDY DESIGN: .: Systematic Review. OBJECTIVE: .: The aim of this study was to investigate, quantify, compare and compile the various mesenchymal stem cell tissue sources within human spinal tissues to act as a compendium for clinical and research application. SUMMARY OF BACKGROUND DATA: .: Recent years have seen a dramatic increase in academic and clinical understanding of human mesenchymal stem cells (MSCs). Previously limited to cells isolated from bone marrow, the past decade has illicited the characterization and isolation of human MSCs from adipose, bone marrow, synovium, muscle, periosteum, peripheral blood, umbilical cord, placenta and numerous other tissues...
September 6, 2017: Spine
https://www.readbyqxmd.com/read/28885125/risk-factor-analysis-of-kyphotic-malalignment-after-cervical-intramedullary-tumor-resection-in-adults
#14
Satoshi Nori, Akio Iwanami, Akimasa Yasuda, Narihito Nagoshi, Nobuyuki Fujita, Tomohiro Hikata, Mitsuru Yagi, Takashi Tsuji, Kota Watanabe, Suketaka Momoshima, Morio Matsumoto, Masaya Nakamura, Ken Ishii
OBJECTIVE A number of studies have reported that surgery for cervical intramedullary tumors via the posterior approach can result in postoperative sagittal malalignment of the cervical spine; however, the risk factors remain unclear. The purpose of this study was to investigate the changes in cervical spinal alignment after surgery for cervical intramedullary tumors in adults and to elucidate the risk factors for cervical spinal sagittal misalignment. METHODS Data for the period from April 2001 to December 2011 for all adults who had undergone surgery for cervical intramedullary spinal cord tumors at a single institution were retrospectively analyzed to determine the postoperative changes in cervical spine alignment...
September 8, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28884108/characteristics-and-clinical-aspects-of-patients-with-spinal-cord-injury-undergoing-surgery
#15
João Simão de Melo-Neto, Lara Eduarda Leite Vidotto, Fabiana de Campos Gomes, Dionei Freitas de Morais, Waldir Antonio Tognola
OBJECTIVE: To identify the characteristics of patients with spinal cord injury (SCI) undergoing surgery. METHODS: Previously, 321 patients with SCI were selected. Clinical and socio-demographic variables were collected. RESULTS: A total of 211 patients were submitted to surgery. Fall and injuries in the upper cervical and lumbosacral regions were associated with conservative treatment. Patients with lesions in the lower cervical spine, worse neurological status, and unstable injuries were associated with surgery...
June 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28882716/remote-thoracic-myelopathy-from-a-spinal-dural-arteriovenous-fistula-at-the-cranio-cervical-junction-case-report-and-review-of-literature
#16
Michael J Lang, Stavropoula Tjoumakaris, Robert H Rosenwasser, Pascal Jabbour
BACKGROUND: The cranio-cervical junction is a rare location for spinal dural arteriovenous fistulas (dAVF). Typically, fistulas at this location present with findings related to intracranial cortical venous reflux or with cervical myelopathy. We present a case of cranio-cervical junction dAVF with isolated clinical and radiographic findings of thoracolumbar myelopathy. CASE DESCRIPTION: A 54 year-old male presented with subacute onset of lower extremity weakness, paresthesias and gait dysfunction...
September 4, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28882602/neurosurgical-aspects-of-dialysis-related-spinal-amyloidosis-report-of-three-cases-and-a-review-of-the-literature
#17
M Dalolio, F Lucarella, P Rampini, G P Bulfamante, S Aldea, P Graveleau, S Gaillard, P Scarone
BACKGROUND AND PURPOSE: Osteoarticular manifestations of beta-2 microglobulin amyloidosis are often diagnosed in long-term dialyzed patients. However, spinal involvement is rare (10-25% of patients), and generally not associated with neurological deterioration. Compression of the spinal cord or roots is extremely rare, and probably under-recognized. METHODS: The authors describe three cases of spinal stenosis presenting with neurological signs in long-term dialyzed patients, prospectively collected over 2 years in two different institutions and treated by surgical decompression...
September 4, 2017: Neuro-Chirurgie
https://www.readbyqxmd.com/read/28882353/neurophysiological-monitoring-in-radiofrequency-ablation-of-spinal-osteoid-osteoma-with-a-progressive-time-and-temperature-protocol-in-children
#18
Mariano A Nöel, Martin J Segura, Sergio Sierre, Ida A Francheri Wilson, Carlos A Tello, Eduardo Galaretto, Rodrigo G Remondino, María E Talarico, Ernesto S Bersusky, Lucas Piantoni
STUDY DESIGN: Retrospective. Level IV Evidence. OBJECTIVE: To assess the utility of intraoperative neurophysiological monitoring (IONM) to detect and eventually prevent impending neurovascular damage during computed tomography (CT)-guided radiofrequency ablation (RFA) of spinal osteoid osteoma (OO) in children. SUMMARY AND BACKGROUND DATA: To our knowledge, this is the first case series of spinal OO in pediatric patients treated at a single center employing IONM during RFA...
September 2017: Spine Deformity
https://www.readbyqxmd.com/read/28881124/minimally-invasive-anterior-decompression-technique-without-instrumented-fusion-for-huge-ossification-of-the-posterior-longitudinal-ligament-in-the-thoracic-spine-technical-note-and-literature-review
#19
Jae Won Yu, Sang-O Yun, Chang-Sheng Hsieh, Sang-Ho Lee
OBJECTIVE: Several surgical methods have been reported for treatment of ossification of the posterior longitudinal ligament (OPLL) in the thoracic spine. Despite rapid innovation of instruments and techniques for spinal surgery, the postoperative outcomes are not always favorable. This article reports a minimally invasive anterior decompression technique without instrumented fusion, which was modified from the conventional procedure. The authors present 2 cases of huge beak-type OPLL...
September 2017: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/28881116/surgical-roles-for-spinal-involvement-of-hematological-malignancies
#20
Sang-Il Kim, Young-Hoon Kim, Kee-Yong Ha, Jae-Won Lee, Jin-Woo Lee
OBJECTIVE: Patients with hematological malignancies frequently encounter spine-related symptoms, which are caused by disease itself or process of treatment. However, there is still lack of knowledge on their epidemiology and clinical courses. The purpose of this article is to review clinical presentations and surgical results for spinal involvement of hematologic malignancies. METHODS: From January 2011 to September 2014, 195 patients (98 males and 97 females) suffering from hematological malignancies combined with spinal problems were retrospectively analyzed for clinical and radiological characteristics and their clinical results...
September 2017: Journal of Korean Neurosurgical Society
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