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Mesenchymal hamartoma

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https://www.readbyqxmd.com/read/27888828/nasal-chondromesenchymal-hamartoma-a-rare-nasal-benign-tumor
#1
Hakan Avcı, Şenol Çomoğlu, Erkan Öztürk, Bilge Bilgiç, Ökkeş Erkan Kıyak
Nasal chondromesenchymal hamartoma (NCMH) is a rare nasal benign tumor, which arises from the nasal cavity or paranasal sinuses. In this article, we present a five-year-old male patient with rhabdomyosarcoma unity in remission that emerged with nasal obstruction. Synchronous diagnosis of pediatric tumors such as pleuropulmonary blastoma in the literature is a remarkable finding. We found a mass within the left nasal cavity originating from superior portion of nasal septum, extending to the olfactory cleft and resected all tumor via endoscopic surgical approach...
September 2016: Kulak Burun Boğaz Ihtisas Dergisi: KBB, Journal of Ear, Nose, and Throat
https://www.readbyqxmd.com/read/27833980/mesenchymal-hamartoma-of-the-left-liver-lobe-in-an-18-month-old-female-patient
#2
Emil Radu Iacob, Călin Marius Popoiu, Alexandra Nyiredi, LaurenŢiu Mogoantă, Oana Badea, Eugen Sorin Boia
Mesenchymal hamartoma of the liver (MHL) is a benign and rare hepatic lesion, with an uncertain etiology and a potential for developing into an undifferentiated distant embryonal sarcoma after an incomplete resection. It mainly presents as progressive abdominal distension with normal blood works. Most cases are diagnosed in the first two years of life, with a higher frequency in boys and on the right liver. We report the case of a mesenchymal hamartoma of the left liver in an 18-month-old girl, with a rough evolution and a literature review...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/27721599/expression-of-ck14-and-vimentin-in-adenomatoid-odontogenic-tumor-and-dentigerous-cyst
#3
Muniswamappa Sudhakara, S Puranik Rudrayya, Srineevas S Vanaki, RamanPreet Kaur Bhullar, M S Shivakumar, Mahadevi Hosur
BACKGROUND: Origin of adenomatoid odontogenic tumor (AOT) has long been a controversy, and the issue of it being a neoplasm or hamartoma was a subject of debate for a long time. Earlier it was grouped under a mixed group of odontogenic tumors considering the varying degrees of inductive changes. Recently, the WHO classification states that the presence of hard tissue within AOT was not due to induction but was rather a metaplastically produced mineralization and hence the tumor was reclassified under a group of tumors arising from odontogenic epithelium...
September 2016: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/27691780/torsion-of-a-mesenchymal-hamartoma-of-the-liver-in-a-1-year-old-boy-case-report
#4
Marko Bašković, Maja Đinkić, Božidar Župančić, Jasminka Stepan, Lucija Čizmić
We report a case of a one-year-old boy who was referred to our clinic suspected of having acute abdomen. On physical examination, the abdomen was soft, diffusely tender with weak peristalsis. Ultrasonography and MRI of the right hemiabdomen demonstrated a well-defined, solid, expansive formation with slightly lobulated contours and an interspersed inhomogeneous structure with overall dimensions of 59 × 45 × 50 mm. After midline laparotomy was performed, a cystic tumor was found, twisted around a pedicle which was arising from the falciform ligament and it measured 5-6 cm in diameter...
October 3, 2016: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/27684838/uncommon-liver-tumors-case-report-and-literature-review
#5
Chia-Hung Wu, Nai-Chi Chiu, Yi-Chen Yeh, Yu Kuo, Sz-Shian Yu, Ching-Yao Weng, Chien-An Liu, Yi-Hong Chou, Yi-You Chiou
BACKGROUND: Beside hepatocellular carcinoma, metastasis, and cholangiocarcinoma, the imaging findings of other relatively uncommon hepatic lesions are less discussed in the literature. Imaging diagnosis of these lesions is a daily challenge. In this article, we review the imaging characteristics of these neoplasms. METHODS: From January 2003 to December 2014, 4746 patients underwent liver biopsy or hepatic surgical resection in our hospital. We reviewed the pathological database retrospectively...
September 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27631514/egfr-exon-20-insertion-duplication-mutations-characterize-fibrous-hamartoma-of-infancy
#6
Jason Y Park, Cynthia Cohen, Dania Lopez, Erica Ramos, Jennifer Wagenfuehr, Dinesh Rakheja
Fibrous hamartoma of infancy (FHI) is a benign mesenchymal tumor histologically characterized by a mixture of intersecting fascicles of fibroblasts/myofibroblasts in collagenous stroma, nests of primitive oval or stellate cells in basophilic mucoid stroma, and mature adipose tissue. We hypothesized that FHI, because of histologic overlap with mesenchymal overgrowth tumors seen in CLOVES (Congenital Lipomatous Overgrowth with Vascular, Epidermal, Skeletal anomalies) and Proteus syndromes, may harbor mutations in signaling pathways associated with cellular proliferation...
September 14, 2016: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/27610342/history-of-the-infantile-hepatic-hemangioma-from-imaging-to-generating-a-differential-diagnosis
#7
REVIEW
Maria Gnarra, Gerald Behr, Alison Kitajewski, June K Wu, Sudha A Anupindi, Carrie J Shawber, Nick Zavras, Dimitrios Schizas, Chris Salakos, Konstantinos P Economopoulos
We aim to provide an up-to-date summary of infantile hepatic hemangioma (IHH) and its misnomers and to dialectically present the differential diagnosis of these rare entities of the liver. Eligible peer-reviewed articles on hepatic infantile hemangiomas, published between 2000 and 2015, were reviewed for this study. IHH is the most common hepatic vascular tumor in children. Once a liver mass is identified in an infant, the differential diagnosis ranges from vascular malformations to benign and malignant tumors including mesenchymal hamartoma, hepatoblastoma, metastatic neuroblastoma, so careful physical examination, imaging studies, and, if indicated, tumor markers and biopsy, are of pivotal importance to ascertain the correct diagnosis...
August 8, 2016: World Journal of Clinical Pediatrics
https://www.readbyqxmd.com/read/27526937/mri-of-paediatric-liver-tumours-how-we-review-and-report
#8
REVIEW
Susan C Shelmerdine, Derek J Roebuck, Alexander J Towbin, Kieran McHugh
Liver tumours are fortunately rare in children. Benign tumours such as haemangiomas and cystic mesenchymal hamartomas are typically seen in infancy, often before 6 months of age. After that age, malignant hepatic tumours increase in frequency. The differentiation of a malignant from benign lesion on imaging can often negate the need for biopsy. Ultrasound is currently the main screening tool for suspected liver pathology, and is ideally suited for evaluation of hepatic lesions in children due to their generally small size...
August 15, 2016: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/27525242/prolonged-air-leakage-caused-by-mesenchymal-cystic-hamartoma-of-the-lung
#9
Young Uk Lee, Jang Hoon Lee, Jong Hyun Baek
A 16-year-old girl was transferred to the department of thoracic and cardiovascular surgery because of a spontaneous pneumothorax with prolonged air leakage. Chest computed tomography demonstrated a cystic lesion measuring 2×3 cm and involving the left upper lobe. Left upper lobectomy was performed via video-assisted thoracoscopic surgery. A pathologic examination of the specimen revealed a mesenchymal cystic hamartoma. Despite the rarity of pulmonary mesenchymal cystic hamartoma, it should be considered a potential cause of pneumothorax for patients with a large pulmonary cyst...
August 2016: Korean Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27516388/catenin-delta-1-ctnnd1-phosphorylation-controls-the-mesenchymal-to-epithelial-transition-in-astrocytic-tumors
#10
Jin Yang, Alexander G Bassuk, Juliane Merl-Pham, Chun-Wei Hsu, Diana F Colgan, Xiaorong Li, Kit Sing Au, Lijuan Zhang, Scott Smemo, Sally Justus, Yasunori Nagahama, Andrew J Grossbach, Matthew A Howard, Hiroto Kawasaki, Neil A Feldstein, William B Dobyns, Hope Northrup, Stefanie M Hauck, Marius Ueffing, Vinit B Mahajan, Stephen H Tsang
Inactivating mutations of the TSC1/TSC2 complex (TSC1/2) cause tuberous sclerosis (TSC), a hereditary syndrome with neurological symptoms and benign hamartoma tumors in the brain. Since TSC effectors are largely unknown in the human brain, TSC patient cortical tubers were used to uncover hyperphosphorylation unique to TSC primary astrocytes, the cell type affected in the brain. We found abnormal hyperphosphorylation of catenin delta-1 S268, which was reversible by mTOR-specific inhibitors. In contrast, in three metastatic astrocytoma cell lines, S268 was under phosphorylated, suggesting S268 phosphorylation controls metastasis...
August 11, 2016: Human Molecular Genetics
https://www.readbyqxmd.com/read/27468623/-liver-transplantation-for-benign-liver-tumor-six-cases-report-and-literature-review
#11
L J Wang, Y M Zhang, Y L Deng, H Zheng, C Pan, Z Y Shen
OBJECTIVE: To analyse and explore the indications and efficacy of liver transplantation for benign liver tumor. METHODS: From Jan.2001 to Dec.2014, 6 patients, incluing 3 males and 3 females, with benign liver tumor underwent liver transplantation in our department.There were 2 cases of hepatic epithelioid hemangioendothelioma, 1 case of hepatic cavernous hemangioma, 1 case of liver mesenchymal hamartoma, 1 case of hilar bile duct mucinous cystadenoma, and 1 case of hepatic adenoma...
July 12, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/27299150/rhabdomyomatous-mesenchymal-hamartoma-presenting-as-a-skin-tag-in-a-newborn
#12
Natalia M Fontecilla, Nicole A Weitz, Christina Day, Alyssa R Golas, Marc E Grossman, Robert Reiffel
No abstract text is available yet for this article.
May 2016: JAAD Case Reports
https://www.readbyqxmd.com/read/27194882/compound-composite-odontoma
#13
G Girish, Radhika M Bavle, Manish Kumar Singh, Sahana N Prasad
The term odontoma has been used as a descriptor for any tumor of odontogenic origin. It is a growth in which both epithelial and mesenchymal cells exhibits complete differentiation. Odontomas are considered as hamartomas rather than true neoplasm. They are usually discovered on routine radiographic examination. Odontomas, according to the World Health Organization, are classified into complex odontoma and compound odontomas. The present paper reports a case of compound composite odontomas.
January 2016: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/26858497/hepatic-cystic-mesenchymal-hamartoma
#14
Debraj Sen, Y S Gulati, Anusree Majumder, Saikat Bhattacharjee, Ritwik Chakrabarti
No abstract text is available yet for this article.
December 2015: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/26816995/multiple-compond-odontomas-in-the-jaws-a-rare-case-report
#15
Pavan Kumar Gujjar, Priya Sahni, Treville Pereira, Jyoti Zingade
Odontomas are tumours of odontogenic origin. In these tumours both the epithelial and mesenchymal cells undergo differentiation to form enamel and dentin with variable amounts of cementum and pulp tissue. The odontomas represent a hamartoma rather than a neoplasm. When the enamel and dentin are laid down in an organized manner it is termed as a compound odontoma wherein the tumour forms a collection of small structures resembling teeth. On the other hand, an irregular mass with no similarity to teeth is termed as a complex odontoma...
December 2015: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/26601559/middle-turbinate-chondro-osseous-respiratory-epithelial-adenomatoid-hamartoma
#16
A Perić, B Vukomanović-Durđević, I Stanojević
OBJECTIVE: Chondroosseous respiratory epithelial adenomatoid hamaroma (COREAH) is an extremely rare, developmental malformation. COREAH is characterized by a spectrum of chondro-osseous metaplasia that arise from the mesenchymal stroma, and it includes dilated submucosal glands lined with respiratory epithelium. This case report aimed to describe a COREAH that originated in the nasal cavity. CASE REPORT: A 68-year-old woman presented with unilateral nasal obstruction...
2015: B-ENT
https://www.readbyqxmd.com/read/26588344/folliculosebaceous-cystic-hamartoma-with-spindle-cell-lipoma-like-stromal-features
#17
Catherine M Nguyen, Hadas Skupsky, David Cassarino
Folliculosebaceous cystic hamartoma is a distinctive cutaneous hamartoma composed of follicular, sebaceous, and mesenchymal components. The lesions are most commonly found on the face and scalp of young adults, with approximately 30% occurring in the nasal or paranasal regions of the face. The clinical differential diagnoses are extensive and include epidermoid cyst, dermal nevus, soft fibroma, and adnexal tumors including sebaceous neoplasms. Here, the authors present a case of a 24-year-old man who presented for evaluation of an asymptomatic growth on the nose, which had slowly enlarged over 9 years...
December 2015: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/26504703/urgent-resection-of-bleeding-congenital-mesenchymal-chest-wall-hamartoma-in-an-infant
#18
Jan-Christoph Bieda, Ralf-Bodo Tröbs, Claudia Roll, Rainer Wunsch, Matthias Neid
We report a case with prenatally diagnosed large cystic-solid mesenchymal chest wall hamartoma. An attempt of conservative management was made however repeated intralesional hemorrhage led to enlargement and severe anemia which required urgent resection at the age of 8 weeks. The infant had an unimpaired development over a follow-up of 4 years.
2013: GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW
https://www.readbyqxmd.com/read/26500976/mesenchymal-hamartoma-of-chest-wall-in-an-infant-mimicking-persistent-pneumonia
#19
Amitabh Singh, Rachna Seth, Gautham Pai, Lesa Dawman, Amit Satapathy
Mesenchymal Hamartoma of the chest wall (MHCW) is a very rare benign tumour. They are usually discovered in infancy. Spontaneous regression is known to occur in this benign condition. Management is surgical removal of mass if respiratory compromise is present. Conservative management is preferred modality in asymptomatic children as malignant transformation is not reported. Herein, we present a case of MHCW in a 5 month old infant presenting with acute respiratory distress with history of respiratory problem at 3 months of age...
September 2015: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/26444007/synchronous-mucosal-schwann-cell-hamartomas-in-a-young-adult-suggestive-of-mucosal-schwann-cell-harmatomatosis-a-case-report
#20
Jeong Mo Bae, Joon Young Lee, Junhun Cho, Sang Ah Lim, Gyeong Hoon Kang
BACKGROUND: Mucosal Schwann-cell hamartoma is a rare mesenchymal polyp that presents in the intestine. Despite lacking ganglion cells, it resembles a gastrointestinal ganglioneuroma. CASE PRESENTATION: We report a case of synchronous mucosal Schwann-cell hamartomas in a young male patient, who presented with a single discrete polyp in the mid-rectum and multiple polypoid mucosal lesions in the distal rectum. CONCLUSION: To the best of our knowledge, this is the first report of a case of multiple mucosal Schwann-cell hamartomas...
2015: BMC Gastroenterology
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