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pancretic cancer

Mitchell L Ramsey, Darwin L Conwell, Phil A Hart
Chronic pancreatitis is a disease that leads to irreversible changes in the pancreatic morphology and function. The loss of function can lead to diabetes mellitus and exocrine pancreatic insufficiency. The inflammation and fibrosis can also lead to other complications including a chronic abdominal pain syndrome, metabolic bone disease, and pancretic cancer. This article reviews our current understanding of the mechanisms and management of these complications of chronic pancreatitis.
July 2017: Digestive Diseases and Sciences
Mario Zovak, Dubravka Mužina Mišić, Goran Glavčić
Surgical resection of pancreatic cancer offers the only chance for prolonged survival. Pancretic resections are technically challenging, and are accompanied by a substantial risk for postoperative complications, the most significant complication being a pancreatic fistula. Risk factors for development of pancreatic leakage are now well known, and several prophylactic pharmacological measures, as well as technical interventions have been suggested in prevention of pancreatic fistula. With better postoperative care and improved radiological interventions, most frequently complications can be managed conservatively...
October 2014: Hepatobiliary Surgery and Nutrition
M Trede, H D Saeger, G Schwall, B Rumstadt
INTRODUCTION: Looking back at the initially dismal record for pancreatic cancer surgery - Whipple himself felt that a 30-35% mortality was justifiable (!) - significant progress has been made. PROGRESS: The operative mortality has fallen below 5% and the serious complications of pancretic resections such as leaks and haemorrhage have been reduced to some 10% and we are better equipped to deal with these if they occur. The 5-year-survival of patients in whom pancreatic cancer was amenable to an R0-resection has risen to 30%...
April 1998: Langenbeck's Archives of Surgery
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