Richard Omore, Alex O Awuor, Billy Ogwel, Caleb Okonji, Catherine Sonye, Caren Oreso, Victor Akelo, Manase Amollo, Isaiah Ogudi, Raphael O Anyango, Marjorie Audi, Evans Apondi, Laura Riziki, Lilian Ambila, Nasrin Dilruba, Erick Muok, Stephen Munga, John B Ochieng, Karen L Kotloff
BACKGROUND: Although Shigella is an important cause of diarrhea in Kenyan children, robust research platforms capable of conducting incidence-based Shigella estimates and eventual Shigella- targeted clinical trials are needed to improve Shigella -related outcomes in children. Here, we describe characteristics of a disease surveillance platform whose goal is to support incidence and consequences of Shigella diarrhea as part of multicounty surveillance aimed at preparing sites and assembling expertise for future Shigella vaccine trials...
March 2024: Open Forum Infectious Diseases