Neerja Bhatla, Richard Muwonge, Sylla G Malvi, Smita Joshi, Usha Rani Reddy Poli, Eric Lucas, Pulikkottil O Esmy, Yogesh Verma, Anand Shah, Eric Zomawia, Sharmila Pimple, Kasturi Jayant, Sanjay Hingmire, Aruna Chiwate, Shachi Vashist, Gauravi Mishra, Radhika Jadhav, Maqsood Siddiqi, Devasena Anantharaman, Gitika Panicker, Julia Butt, Subha Sankaran, Thiraviam Pillai Rameshwari Ammal Kannan, Rintu Varghese, Purnima Kartha, M Radhakrishna Pillai, Tim Waterboer, Martin Müller, Peter Sehr, Elizabeth R Unger, Rengaswamy Sankaranarayanan, Partha Basu
Long-term follow-up of a cohort of unmarried girls who received one, two, or three doses of quadrivalent HPV vaccine, between 10 and 18 years of age, in an Indian multi-centric study allowed us to compare antibody responses between the younger and older age cohorts at 10-years post-vaccination, and study the impact of initiation of sexual activity and cervical HPV infections on antibody levels. Among the younger (10-14 years) recipients of a single dose, 97.7% and 98.2% had detectable binding antibody titers against HPV 16 and HPV 18 respectively at ten years post-vaccination...
December 15, 2023: Human Vaccines & Immunotherapeutics