Yoshihiko Saeki, Mayumi Saito, Takuya Irie, Fujiko Itoh, Akiko Enatsu, Hiroko Komura, Miho Fujii, Ryota Fujii, Natsuko Hidaka, Toshiyuki Maehama, Nobuhiko Shirasu, Tomoo Waseda, Takeo Shibata, Emi Takada, Kazuki Mibe, Jinichi Sakamoto, Sousuke Yamada, Masahiro Takakura, Toshiyuki Sasagawa
This study investigated the efficacy of the prophylactic human papillomavirus (HPV) vaccine, which was initiated between 2009 and 2013 in Japan. The study involved 1529 eligible women aged 16-39 years who visited 11 outpatient clinics in Japan for various reasons. These patients underwent HPV genotype analysis and a Pap test of cervical cell samples. A total of 299 women (19.6%) had received the prophylactic HPV vaccine (bivalent:quadrivalent vaccine ratio = 2:1). Of the 5062 participants in the Japanese Human Papillomavirus Disease Education and Research Survey (J-HERS 2011), which was conducted in the pre-vaccination era, 3236 eligible participants were included as controls...
February 2024: Journal of Medical Virology