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Variability in practice

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https://www.readbyqxmd.com/read/29913302/weed-hygiene-practices-in-rural-industries-and-public-land-management-variable-knowledge-patchy-implementation-inconsistent-coordination
#1
Nicholas Gill, Sonia Graham, Rebecca Cross, Eli Taylor
Weed management science and practice largely focuses on eradicating, containing and reducing existing weed populations; the focus is on plants in situ. More recently, the redefinition of biosecurity to include weeds has seen greater attention paid to preventing the introduction of weeds to previously uninfested areas within countries. Thus weed hygiene has come to the fore, with a growing number of publications recommending a diverse range of practices to minimise the spread of weeds across farm, regional and state boundaries...
June 15, 2018: Journal of Environmental Management
https://www.readbyqxmd.com/read/29913113/the-frequency-of-false-allegations-of-child-sexual-abuse-a-critical-review
#2
William O'Donohue, Caroline Cummings, Brendan Willis
The rate of false allegations has been a topic of research spanning back to as early as the 1970s. Studies have often relied on data gathered by Child Protective Services workers and court administrators. Some researchers have also used hypothetical scenarios to estimate rates. However, given the plethora of sampling methods, there is a large variation in estimated rates of false allegations of sexual abuse depending on the data source and context of the allegation. Additionally, methodological problems such as unclear or invalid criteria used to judge truth or falsity of an allegation, unrepresentative samples, and ignoring important contextual variables such as the stage at which an allegation is made, currently all render the determination of actual rates of false child sexual abuse allegations to be unknown...
June 18, 2018: Journal of Child Sexual Abuse
https://www.readbyqxmd.com/read/29913086/training-pilots-for-unexpected-events-a-simulator-study-on-the-advantage-of-unpredictable-and-variable-scenarios
#3
Annemarie Landman, Peter van Oorschot, M M René van Paassen, Eric L Groen, Adelbert W Bronkhorst, Max Mulder
OBJECTIVE: This study tested whether simulator-based training of pilot responses to unexpected or novel events can be improved by including unpredictability and variability in training scenarios. BACKGROUND: Current regulations allow for highly predictable and invariable training, which may not be sufficient to prepare pilots for unexpected or novel situations in-flight. Training for surprise will become mandatory in the near future. METHOD: Using an aircraft model largely unfamiliar to the participants, one group of 10 pilots (the unpredictable and variable [U/V] group) practiced responses to controllability issues in a relatively U/V manner...
June 1, 2018: Human Factors
https://www.readbyqxmd.com/read/29913021/implementation-of-a-clinical-prediction-model-using-daily-postnatal-weight-gain-birth-weight-and-gestational-age-to-risk-stratify-rop
#4
Kortany McCauley, Anupama Chundu, Helen Song, Robin High, Donny Suh
PURPOSE: To develop a simple prognostic model using postnatal weight gain, birth weight, and gestational age to identify infants at risk for developing severe retinopathy of prematurity (ROP). METHODS: Medical records from two tertiary referral centers with the diagnosis code "Retinopathy of Prematurity" were evaluated. Those with a birth weight of 1,500 g or less, gestational age of 30 weeks or younger, and unstable clinical courses were included. Multivariate regression analysis was applied to transform three independent variables into a growth rate algorithm...
June 18, 2018: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29912794/intraindividual-and-interindividual-variability-of-olanzapine-trough-concentrations-in-patients-treated-with-the-long-acting-injectable-formulation
#5
Sara Baldelli, Massimo C Mauri, Chiara Di Pace, Silvia Paletta, Alessandra Reggiori, Chiara Rovera, Emilio Clementi, Dario Cattaneo
BACKGROUND: A long-acting injectable (LAI) formulation of olanzapine has been developed as an alternative to oral regimens. A therapeutic range of 20 to 80 ng/mL for oral olanzapine trough concentrations has been proposed. Here, we sought to investigate the intraindividual and interindividual variability of olanzapine concentrations with time in patients on maintenance therapy with the LAI formulation carried out in the routine clinical practice. METHODS: To address this issue, we carried out a retrospective analysis of therapeutic drug monitoring of olanzapine concentrations in 21 schizophrenic patients on maintenance LAI olanzapine...
June 14, 2018: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29912739/minimally-invasive-left-ventricular-assist-device-implantation-implementation-early-in-a-surgical-career
#6
Hannah J Voorhees, Erik N Sorensen, Chetan Pasrija, Francesca M Boulos, Si M Pham, Bartley P Griffith, Zachary N Kon
OBJECTIVE: Several centers have presented minimally invasive surgical approaches to centrifugal left ventricular assist device implantation. Although minimally invasive implantation has been successfully performed by experienced surgeons, at large implanting centers, it is unknown whether these techniques are widely adoptable. We evaluated the experience of a surgeon early in his career with conventional and minimally invasive approaches to device implantation. METHODS: All consecutive left ventricular assist device implantations by a single surgeon in the first year of practice (2015-2016) were retrospectively reviewed...
June 15, 2018: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/29912592/breast-cancer-during-pregnancy-results-of-maternal-and-perinatal-outcomes-in-a-single-institution-and-systematic-review-of-the-literature
#7
Natalia R Gomez-Hidalgo, Elsa Mendizabal, Laura Joigneau, Pilar Pintado, Juan De Leon-Luis
To compare the maternal and the perinatal variables of the patients with pregnancy associated breast cancer (PABC) and the pregnant patients without breast cancer (PNABC), we retrospectively included 13 PABC cases and 66.265 PNABC patients. The PABC patients presented a lower mean gestational age at their delivery and had higher induction of labour and prematurity rates. A diagnosis was performed before stage III in 77% of the cases. The overall survival was 90%; moreover, we collected 16 manuscripts when gathering data from 1581 patients with PABC...
June 18, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29912235/-peripartum-cardiomyopathy-a-little-known-disease
#8
Angela Beatrice Scardovi, Renata De Maria
Peripartum cardiomyopathy (PPCM) is a relatively rare cardiac disease that manifests itself in the final stage of pregnancy and in the first months after delivery in women with no previous history of cardiovascular disease. The incidence of PPCM varies widely across geographic areas and seems to be on the rise as a result of increased awareness and socioeconomic changes. PPCM recognizes a still partially undefined multifactorial etiology. Various pathogenetic hypotheses have been proposed, that range from autoimmune mechanisms to myocarditis to the hormonal hypothesis for aberrant, antiangiogenic and cardiotoxic prolactin (PRL) production, apoptosis, prolonged exposure to tocolytic drugs, malnutrition and genetic predisposition...
April 2018: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/29912092/effects-of-glucocorticoids-on-hospitalized-children-with-anaphylaxis
#9
Yusuke Okubo, Nobuaki Michihata, Naho Morisaki, Koichi Yoshida, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga
BACKGROUND: The benefits of glucocorticoid treatment and recent trends of adjunctive treatments during episodes of anaphylaxis remain unclear. OBJECTIVES: The aims of this study were to investigate the recent practice patterns and compare the effects of glucocorticoid for children hospitalized with anaphylaxis. METHODS: Using the Japanese Diagnosis Procedure Combination inpatient database, we compared the length of hospital stay, risk of 10-day readmission, and total hospitalization cost between the steroid and nonsteroid groups...
June 14, 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29912086/current-practices-in-pediatric-emergency-medicine-fellowship-trauma-training
#10
Diana T Fleisher, Rachel J Katz-Sidlow, James A Meltzer
OBJECTIVE: The management of injured children is a required element of pediatric emergency medicine (PEM) fellowship training. Given the relatively infrequent exposure of trainees to major trauma, it is important to understand how programs train fellows and assess their competency in pediatric trauma. METHODS: An online survey was sent to 84 PEM fellowship program directors (PDs). Program directors were asked to describe their program's characteristics, the degree of fellow independence, educational techniques used to train fellows in trauma, and their expectation of fellows' competency in 14 core trauma-related skills upon graduation...
June 14, 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29911631/the-effectiveness-of-a-nursing-staff-development-intervention-to-improve-pain-management-a-randomized-controlled-trial
#11
S Zoëga, S E Ward, R C Serlin, H Sveinsdottir, E Th Gretarsdottir, N Fridriksdottir, E J G Hafsteinsdottir, S Gunnarsdóttir
Aims To test the effectiveness of the Pain Resource Nurse (PRN) education program in a university hospital. Methods This was a randomized controlled trial. Two nurses from each of the 23 participating surgical and medical units were selected to participate in the PRN program. The program consisted of a three day course in pain management with a structured follow up. After a baseline measurement, the units were randomized to either receive the intervention or to serve as a wait-list control. The control group received the intervention following a second data collection 10 months from baseline...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29910764/the-use-of-footstep-sounds-as-rhythmic-auditory-stimulation-for-gait-rehabilitation-in-parkinson-s-disease-a-randomized-controlled-trial
#12
Mauro Murgia, Roberta Pili, Federica Corona, Fabrizio Sors, Tiziano A Agostini, Paolo Bernardis, Carlo Casula, Giovanni Cossu, Marco Guicciardi, Massimiliano Pau
Background: The use of rhythmic auditory stimulation (RAS) has been proven useful in the management of gait disturbances associated with Parkinson's disease (PD). Typically, the RAS consists of metronome or music-based sounds (artificial RAS), while ecological footstep sounds (ecological RAS) have never been used for rehabilitation programs. Objective: The aim of this study was to compare the effects of a rehabilitation program integrated either with ecological or with artificial RAS...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29910741/physiology-and-pathophysiology-in-ultra-marathon-running
#13
REVIEW
Beat Knechtle, Pantelis T Nikolaidis
In this overview, we summarize the findings of the literature with regards to physiology and pathophysiology of ultra-marathon running. The number of ultra-marathon races and the number of official finishers considerably increased in the last decades especially due to the increased number of female and age-group runners. A typical ultra-marathoner is male, married, well-educated, and ~45 years old. Female ultra-marathoners account for ~20% of the total number of finishers. Ultra-marathoners are older and have a larger weekly training volume, but run more slowly during training compared to marathoners...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29910706/less-might-be-more-conduction-failure-as-a-factor-possibly-limiting-the-efficacy-of-higher-frequencies-in-rtms-protocols
#14
Islam Halawa, Amir Goldental, Yuichiro Shirota, Ido Kanter, Walter Paulus
Introduction: rTMS has been proven effective in the treatment of neuropsychiatric conditions, with class A (definite efficacy) evidence for treatment of depression and pain (Lefaucheur et al., 2014). The efficacy in stimulation protocols is, however, quite heterogeneous. Saturation of neuronal firing by HFrTMS without allowing time for recovery may lead to neuronal response failures (NRFs) that compromise the efficacy of stimulation with higher frequencies. Objectives: To examine the efficacy of different rTMS temporal stimulation patterns focusing on a possible upper stimulation limit related to response failures...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29910640/gaming-science-innovations-to-integrate-health-systems-science-into-medical-education-and-practice
#15
REVIEW
Earla J White, Joy H Lewis, Lise McCoy
Health systems science (HSS) is an emerging discipline addressing multiple, complex, interdependent variables that affect providers' abilities to deliver patient care and influence population health. New perspectives and innovations are required as physician leaders and medical educators strive to accelerate changes in medical education and practice to meet the needs of evolving populations and systems. The purpose of this paper is to introduce gaming science as a lens to magnify HSS integration opportunities in the scope of medical education and practice...
2018: Advances in Medical Education and Practice
https://www.readbyqxmd.com/read/29910320/the-demands-of-a-women-s-college-soccer-season
#16
Jeremy A Gentles, Christine L Coniglio, Matthew M Besemer, Joshua M Morgan, Michael T Mahnken
The purpose of this study was to use GPS, accelerometers, and session rating of perceived exertion (sRPE) to examine the demands of a Division II women's soccer team. Data was collected on 25 collegiate Division II women's soccer players over an entire regular season (17 matches and 24 practices). ZephyrTM BioHarnesses (BHs) were used to collect tri-axial acceleration information and GPS derived variables for all matches and practices. Acceleration data was used to calculate Impulse Load, a measure of mechanical load that includes only locomotor related accelerations...
February 23, 2018: Sports (Basel)
https://www.readbyqxmd.com/read/29910113/evaluation-of-the-vasoactive-inotropic-score-mid-regional-pro-adrenomedullin-and-cardiac-troponin-i-as-predictors-of-low-cardiac-output-syndrome-in-children-after-congenital-heart-disease-surgery
#17
J L Pérez-Navero, C Merino-Cejas, I Ibarra de la Rosa, S Jaraba-Caballero, M Frias-Perez, E Gómez-Guzmán, M Gil-Campos, M J de la Torre-Aguilar
OBJECTIVE: To determine the predictive value of the inotropic score (IS) and vasoactive-inotropic score (VIS) in low cardiac output syndrome (LCOS) in children after congenital heart disease surgery involving cardiopulmonary bypass (CPB), and to establish whether mid-regional pro-adrenomedullin (MR-proADM) and cardiac troponin I (cTn-I), associated to the IS and VIS scores, increases the predictive capacity in LCOS. DESIGN: A prospective observational study was carried out...
June 14, 2018: Medicina Intensiva
https://www.readbyqxmd.com/read/29909537/existing-agricultural-ecosystem-in-china-leads-to-environmental-pollution-an-econometric-approach
#18
Lei Hongdou, Li Shiping, Li Hao
Sustainable agriculture ensures food security and prevents starvation. However, the need to meet the increasing food demands of the growing population has led to poor and unsustainable agricultural practices, which promote environmental degradation. Given the contributions of agricultural ecosystems to environmental pollution, we investigated the impact of the agricultural ecosystem on environmental pollution in China using time series data from 1960 to 2014. We employed several methods for econometric analysis including the unit root test, Johansen test of cointegration, Granger causality test, and vector error correction model...
June 17, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29909298/aerosol-production-during-autopsies-the-risk-of-sawing-in-bone
#19
Jip M E Pluim, Lucas Jimenez-Bou, Reza R R Gerretsen, Arjo J Loeve
When sawing during autopsies on human remains, fine dust is produced, which consists of particles of sizes that may fall within the human respirable range, and can act as vectors for pathogens. The goal of this study was to explore the potential effects of saw blade frequency and saw blade contact load on the number and size of airborne bone particles produced. The methodology involved the use of an oscillating saw with variable saw blade frequencies and different saw blade contact loads on dry human femora...
June 6, 2018: Forensic Science International
https://www.readbyqxmd.com/read/29909091/clinical-and-pharmacogenetic-determinants-of-5-fluorouracyl-leucovorin-irinotecan-toxicity-results-of-the-petacc-3-trial
#20
Sabine Tejpar, Pu Yan, Hubert Piessevaux, Daniel Dietrich, Peter Brauchli, Dirk Klingbiel, Roberto Fiocca, Mauro Delorenzi, Fred Bosman, Arnaud D Roth
PURPOSE: Irinotecan (CPT-11) in combination with 5-fluorouracil (5FU) is widely used in the treatment of colorectal cancer. We assessed potential clinical variables that may predict toxicity and more specifically the role of UGT1A1 polymorphisms associated with irinotecan toxicity. We used data from the PETACC3 trial, which randomised patients in adjuvant setting to 6 months of leucovorin (LV) and 5FU (LV5/FU2) or LV5/FU2 + irinotecan. PATIENTS AND METHODS: Clinical and toxicity data were available for 2982 patients, DNA was available for 1200 (40%) of these patients...
June 14, 2018: European Journal of Cancer
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