keyword
MENU ▼
Read by QxMD icon Read
search

SPV

keyword
https://www.readbyqxmd.com/read/27922194/pharmacodynamic-response-profiles-of-anxiolytic-and-sedative-drugs
#1
Xia Chen, Freerk Broeyer, Marieke de Kam, Joke Baas, Adam Cohen, Joop van Gerven
INTRODUCTION: Centrally-acting acutely anxiolytic drugs, like benzodiazepines, barbiturates and gabapentinoids, affect various central nervous system (CNS) functions, which reflect not only their anxiolytic effects but also neuropsychological side-effects. To validate the pharmacodynamic biomarkers for GABA-ergic anxiolytics, this study determined the pharmacodynamics of two anxiolytics and a non-anxiolytic control and linked them to their anxiolytic and sedative effects, during an anxiety-challenge study day...
December 6, 2016: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/27864781/isolation-identification-and-high-throughput-screening-of-neutral-lipid-producing-indigenous-microalgae-from-south-african-aquatic-habitats
#2
S T Gumbi, B M Majeke, A O Olaniran, T Mutanda
Exploring indigenous microalgae capable of producing significant amounts of neutral lipids through high-throughput screening is crucial for sustainable biodiesel production. In this study, 31 indigenous microalgal strains were isolated from diverse aquatic habitats in KwaZulu-Natal, South Africa. Eight superior lipid-producing strains were selected for further analysis, based on Nile red fluorescence microscopy screening. The microalgal isolates were identified to belong to the genera Chlorella, Neochloris and Chlamydomonas via morpho-taxonomic and molecular approach by 18S rRNA gene sequencing...
November 18, 2016: Applied Biochemistry and Biotechnology
https://www.readbyqxmd.com/read/27831573/electron-acceptor-of-ni-decorated-porous-carbon-nitride-applied-in-photocatalytic-hydrogen-production
#3
Lingling Bi, Dedong Meng, Qijing Bu, Yanhong Lin, Dejun Wang, Tengfeng Xie
Nickel, a non-noble metal, is one of the most promising candidates for photocatalysis because it is inexpensive and an earth-abundant metal. Herein, Ni/CM-C3N4 nanocomposites with Ni as a cocatalyst were synthesized by a simple solvothermal method. Field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM) and X-ray diffraction (XRD) confirmed that Ni nanoparticles were loaded onto the surface of CM-C3N4. The prepared Ni/CM-C3N4 nanocomposites exhibited an enhanced hydrogen evolution activity...
November 10, 2016: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/27821973/abnormal-bias-in-subjective-vertical-perception-in-a-post-stroke-astasia-patient
#4
Keisuke Tani, Akiyoshi Matsugi, Shintaro Uehara, Daisuke Kimura
[Purpose] Post-stroke astasia is an inability to stand without external support despite having sufficient muscle strength. However, the dysfunction underlying astasia is unclear. We tested the hypothesis that astasia is the result of an abnormal bias in vertical perception, especially subjective postural vertical (SPV), mediated by somatosensory inputs. [Subjects and Methods] A patient with a right posterolateral thalamus hemorrhage had a tendency to fall toward the contralesional side during standing after 8 weeks of treatment...
October 2016: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/27800482/stabilization-of-the-virulence-plasmid-pslt-of-salmonella-typhimurium-by-three-maintenance-systems-and-its-evaluation-by-using-a-new-stability-test
#5
Damián Lobato-Márquez, Laura Molina-García, Inma Moreno-Córdoba, Francisco García-Del Portillo, Ramón Díaz-Orejas
Certain Salmonella enterica serovars belonging to subspecies I carry low-copy-number virulence plasmids of variable size (50-90 kb). All of these plasmids share the spv operon, which is important for systemic infection. Virulence plasmids are present at low copy numbers. Few copies reduce metabolic burden but suppose a risk of plasmid loss during bacterial division. This drawback is counterbalanced by maintenance modules that ensure plasmid stability, including partition systems and toxin-antitoxin (TA) loci...
2016: Frontiers in Molecular Biosciences
https://www.readbyqxmd.com/read/27780297/pharmacokinetics-and-pharmacodynamics-of-a-new-highly-concentrated-intranasal-midazolam-formulation-for-conscious-sedation
#6
Lenneke Schrier, Rob Zuiker, Frans W H M Merkus, Erica S Klaassen, Zheng Guan, Bert Tuk, Joop M A van Gerven, Ronald van der Geest, Geert Jan Groeneveld
AIM: To evaluate the pharmacokinetics, pharmacodynamics, nasal tolerance and effects on sedation of a highly concentrated aqueous intranasal midazolam formulation (Nazolam) and to compare these to intravenous midazolam. METHODS: In this four-way crossover, double-blind, double-dummy, randomized, placebo-controlled study, 16 subjects received 2.5 mg Nazolam, 5.0 mg Nazolam, 2.5 mg intravenous midazolam or placebo on different occasions. Pharmacokinetics of midazolam and α-hydroxy-midazolam were characterized and related to outcome variables for sedation (Saccadic Peak Velocity, the Bond and Lader Visual Analogue Scale for sedation, the Simple Reaction Time Task and the Observer's Assessment of Alertness/Sedation)...
October 25, 2016: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/27695992/analysis-of-the-blood-supply-to-the-post-fracture-edentulous-mandible-study-by-colour-doppler-sonography
#7
Júlio Cezar M A Mancini, Márcio Ricardo Taveira Garcia, Ilka Regina Souza de Oliveira, Ronaldo Rodrigues de Freitas, João Gualberto C Luz
PURPOSE: This study assessed the arterial blood supply to the mandible of edentulous patients treated for mandibular fractures using colour Doppler ultrasound. METHODS: The blood supply of edentulous patients surgically treated for mandibular fractures (group A) and edentulous fracture-free individuals (group B) was assessed. Only the fractured sides were evaluated in the first group (N = 17), whereas each side was evaluated in the second group (N = 20)...
October 1, 2016: Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27679549/pancreaticoduodenectomy-for-ductal-adenocarcinoma-of-the-pancreatic-head-with-venous-resection
#8
Vojko Flis, Stojan Potrc, Nina Kobilica, Arpad Ivanecz
BACKGROUND: Recent reports have shown that patients with vascular tumour invasion who undergo concurrent vascular resection can achieve long-term survival rates equivalent to those without vascular involvement requiring pancreaticoduodenectomy alone. There is no consensus about which patients benefit from the portal-superior mesenteric vein resection and there is no consensus about the best surgical technique of vessel reconstruction (resection with or without graft reconstruction). As published series are small the aim of this study was to evaluate our experience in pancreatectomies with en bloc vascular resection and reconstruction of vessels...
September 1, 2016: Radiology and Oncology
https://www.readbyqxmd.com/read/27666190/salmonella-spv-locus-suppresses-host-innate-immune-responses-to-bacterial-infection
#9
Shu-Yan Wu, Li-Dan Wang, Jin-Ling Li, Guang-Mei Xu, Mei-Ling He, Yuan-Yuan Li, Rui Huang
Salmonella enterica serovar typhimurium (S. typhimurium) is globally distributed and causes massive morbidity and mortality in humans and animals. S. typhimurium carries Salmonella plasmid virulence (spv) locus, which is highly conserved and closely related to bacterial pathogenicity, while its exact role in host immune responses during infection remains to be elucidated. To counteract the invaders, the host has evolved numerous strategies, among which the innate immunity and autophagy act as the first defense...
September 22, 2016: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/27620878/revised-ct-angiography-venous-score-with-consideration-of-infratentorial-circulation-value-for-diagnosing-brain-death
#10
Antoine J Marchand, Philippe Seguin, Yannick Malledant, Marion Taleb, Hélène Raoult, Jean Yves Gauvrit
BACKGROUND: Computed tomography angiography (CTA) is largely performed in European countries as an ancillary test for diagnosing brain death. However, CTA suffers from a lack of sensitivity, especially in patients who have previously undergone decompressive craniectomy. The aim of this study was to assess the performance of a revised four-point venous CTA score, including non-opacification of the infratentorial venous circulation, for diagnosing brain death. METHODS: A preliminary study of 43 control patients with normal CTAs confirmed that the infratentorial superior petrosal vein (SPV) was consistently visible...
December 2016: Annals of Intensive Care
https://www.readbyqxmd.com/read/27601782/the-effect-of-trial-familiarisation-on-the-validity-and-reproducibility-of-a-field-based-self-paced-vo2max-test
#11
W Lim, D Lambrick, A R Mauger, B Woolley, J Faulkner
The self-paced maximal oxygen uptake (VO2max) test (SPV), which is based on the Borg 6-20 Ratings of Perceived Exertion (RPE) scale, allows participants to self-regulate their exercise intensity during a closed-loop incremental maximal exercise test. As previous research has assessed the utility of the SPV test within laboratory conditions, the purpose to this study was to assess the effect of trial familiarisation on the validity and reproducibility of a field-based, SPV test. In a cross-sectional study, fifteen men completed one laboratory-based graded exercise test (GXT) and three field-based SPV tests...
September 2016: Biology of Sport
https://www.readbyqxmd.com/read/27515038/can-a-central-blood-volume-deficit-be-detected-by-systolic-pressure-variation-during-spontaneous-breathing
#12
Michael Dahl, Chris Hayes, Bodil Steen Rasmussen, Anders Larsson, Niels H Secher
BACKGROUND: Whether during spontaneous breathing arterial pressure variations (APV) can detect a volume deficit is not established. We hypothesized that amplification of intra-thoracic pressure oscillations by breathing through resistors would enhance APV to allow identification of a reduced cardiac output (CO). This study tested that hypothesis in healthy volunteers exposed to central hypovolemia by head-up tilt. METHODS: Thirteen healthy volunteers were exposed to central hypovolemia by 45° head-up tilt while breathing through a facemask with 7...
August 11, 2016: BMC Anesthesiology
https://www.readbyqxmd.com/read/27386107/rheological-baking-and-sensory-properties-of-composite-bread-dough-with-breadfruit-artocarpus-communis-forst-and-wheat-flours
#13
Adegoke H Bakare, Oluwatooyin F Osundahunsi, Joseph O Olusanya
The rheological (Pasting, farinograph, and alveograph) properties of wheat flour (WF) replaced with breadfruit four (05-40%) was analyzed. Baking and sensory qualities of the resulting bread were evaluated. Differences in baking properties of loaves produced under laboratory and industrial conditions were analyzed with t-test, whereas ANOVA was used for other analyses. Peak and final viscosities in the composite blends (CB) ranged from 109.20 to 114.06 RVU and 111.86 to 134.40 RVU, respectively. Dough stability decreased from 9...
July 2016: Food Science & Nutrition
https://www.readbyqxmd.com/read/27352973/salmonella-infection-in-healthy-pet-reptiles-bacteriological-isolation-and-study-of-some-pathogenic-characters
#14
Fabrizio Bertelloni, Marianne Chemaly, Domenico Cerri, Françoise Le Gall, Valentina Virginia Ebani
The fecal samples from 213 captive reptiles were examined, and 29 (13.61%) Salmonella enterica isolates were detected: 14/62 (22.58%) from chelonians, 14/135 (10.37%) from saurians, and 1/16 (6.25%) from ophidians. The isolates were distributed among 14 different serotypes: Miami, Ebrie, Hermannsweder, Tiergarten, Tornov, Pomona, Poona, Goteborg, Abaetetube, Nyanza, Kumasi, Typhimurium, 50:b:z6, 9,12:z29:1,5, and a non-motile serotype with antigenic formula 1,4,[5],12:-:-. Salmonella typhimurium and 50:b:z6 isolates showed the spv plasmid virulence genes, responsible of the capability to induce extra-intestinal infections...
June 2016: Acta Microbiologica et Immunologica Hungarica
https://www.readbyqxmd.com/read/27335768/high-resolution-noncontact-afm-and-kelvin-probe-force-microscopy-investigations-of-self-assembled-photovoltaic-donor-acceptor-dyads
#15
Benjamin Grévin, Pierre-Olivier Schwartz, Laure Biniek, Martin Brinkmann, Nicolas Leclerc, Elena Zaborova, Stéphane Méry
Self-assembled donor-acceptor dyads are used as model nanostructured heterojunctions for local investigations by noncontact atomic force microscopy (nc-AFM) and Kelvin probe force microscopy (KPFM). With the aim to probe the photo-induced charge carrier generation, thin films deposited on transparent indium tin oxide substrates are investigated in dark conditions and upon illumination. The topographic and contact potential difference (CPD) images taken under dark conditions are analysed in view of the results of complementary transmission electron microscopy (TEM) experiments...
2016: Beilstein Journal of Nanotechnology
https://www.readbyqxmd.com/read/27303943/nanophotoactivity-of-porphyrin-functionalized-polycrystalline-zno-films
#16
Celia Rogero, David F Pickup, Jaime Colchero, Eneko Azaceta, Ramón Tena-Zaera, Elisa Palacios-Lidón
Kelvin probe force microscopy in darkness and under illumination is reported to provide nanoscale-resolved surface photovoltage maps of hybrid materials. In particular, nanoscale charge injection and charge recombination mechanisms occurring in ZnO polycrystalline surfaces functionalized with Protoporphyrin IX (H2PPIX) are analyzed. Local surface potential and surface photovoltage maps not only reveal that upon molecular adsorption the bare ZnO work function increases, but also they allow study of its local dependence...
July 6, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27275544/cancer-megafunds-with-in-silico-and-in-vitro-validation-accelerating-cancer-drug-discovery-via-financial-engineering-without-financial-crisis
#17
Xianjin Yang, Edouard Debonneuil, Alex Zhavoronkov, Bud Mishra
Advances in financial engineering are radically reshaping the biomedical marketplace. For instance, new methods of pooling diversified drug development programs by placing them in a special purpose vehicle (SPV) have been proposed to create a securitized cancer megafund allowing for debt and equity participation. In this study, we perform theoretical and numerical simulations that highlight the role of empirical validation of the projects comprising a cancer megafund. We quantify the degree to which the deliberately designed structure of derivatives and investments is key to its liquidity...
June 3, 2016: Oncotarget
https://www.readbyqxmd.com/read/27231429/secondary-varicose-small-pelvic-veins-and-their-treatment-with-micronized-purified-flavonoid-fraction
#18
Yurii T Tsukanov, Anton Y Tsukanov, Evgenii G Levdanskiy
The aim of this study was to examine secondary varicose small pelvic veins (VSPV) and their treatment with micronized purified flavonoid fraction (MPFF). We examined 70 patients with a history of acute iliac thrombosis of > 1 year. Patients with urination difficulties associated with other symptoms (n = 24) received MPFF 1,000 mg once daily for 1 month. Clinical manifestations were assessed by collecting complaints and analyzing results of physician examinations. VSPV was identified in 48 (68.6%) patients, the majority (58%) had grade 2 (7...
June 2016: International Journal of Angiology: Official Publication of the International College of Angiology, Inc
https://www.readbyqxmd.com/read/27229358/surgical-protocol-violations-in-children-with-renal-tumors-provides-an-opportunity-to-improve-pediatric-cancer-care-a-report-from-the-children-s-oncology-group
#19
Peter F Ehrlich, Thomas E Hamilton, Kenneth Gow, Douglas Barnhart, Fernando Ferrer, Jessica Kandel, Richard Glick, Roshni Dasgupta, Arlene Naranjo, Ying He, Elizabeth J Perlman, John A Kalapurakal, Geetika Khanna, Jeffrey S Dome, James Geller, Elizabeth Mullen
BACKGROUND: The purpose of this study was to evaluate the frequency and characteristics of surgical protocol violations (SPVs) among children undergoing surgery for renal tumors who were enrolled on the Children's Oncology Group (COG) renal tumor biology and classification study AREN03B2. METHODS: AREN03B2 was opened in February 2006, and as on March 31, 2013, there were 3,664 eligible patients. The surgical review forms for 3,536 patients with unilateral disease were centrally reviewed for SPVs...
November 2016: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/27199758/serial-measurements-of-splanchnic-vein-diameters-in-rats-using-high-frequency-ultrasound
#20
Bridget M Seitz, Teresa Krieger-Burke, Gregory D Fink, Stephanie W Watts
The purpose of this study was to investigate serial ultrasound imaging in rats as a fully non-invasive method to (1) quantify the diameters of splanchnic veins in real time as an indirect surrogate for the capacitance function of those veins, and (2) assess the effects of drugs on venous dimensions. A 21 MHz probe was used on anesthetized male Sprague-Dawley rats to collect images containing the portal vein (PV), superior mesenteric vein (SMV), abdominal inferior vena cava (IVC), and splenic vein (SpV; used as a landmark in timed studies) and the abdominal aorta (AA)...
2016: Frontiers in Pharmacology
keyword
keyword
85514
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"