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https://www.readbyqxmd.com/read/28514232/ppar%C3%AE-agonists-attenuate-trigeminal-neuropathic-pain
#1
Danielle N Lyons, Liping Zhang, Robert J Danaher, Craig S Miller, Karin N Westlund
The aim of this study is to investigate the role of peroxisome proliferator-activated receptor-gamma isoform (PPARγ), in trigeminal neuropathic pain utilizing a novel mouse trigeminal inflammatory compression (TIC) injury model. The study determined that the PPARγ nuclear receptor plays a significant role in trigeminal nociception transmission, evidenced by: (1) Intense PPARγ immunoreactivity is expressed 3 weeks after TIC nerve injury in the spinal trigeminal caudalis, the termination site of trigeminal nociceptive nerve fibers...
May 16, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28460220/study-on-dynamic-properties-of-the-photoexcited-charge-carriers-at-anatase-tio2-nanowires-fluorine-doped-tin-oxide-interface
#2
Qingqing Qiu, Lingling Xu, Dejun Wang, Yanhong Lin, Tengfeng Xie
The photoexcited electrons transfer dynamics at the TiO2 film/fluorine doped tin oxide (FTO) interface of anatase TiO2 nanowire arrays (NWAs) and QD-sensitized TiO2 NWAs films have been studied by using surface photovoltage (SPV) and transient photovoltage (TPV) techniques. Various SPV and TPV responses were obtained when the laser beam was incident from the front side illumination and back side illumination. Based on the work function values of anatase TiO2 NWAs and FTO, the results indicate that diffusion is the major way for the separation and transfer of the photoexcited charge in the both anatase TiO2 NWAs and QD-sensitized TiO2 NWAs films under front side illumination...
April 25, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28430087/modification-of-two-capripoxvirus-quantitative-real-time-pcr-assays-to-improve-diagnostic-sensitivity-and-include-beta-actin-as-an-internal-positive-control
#3
Amaresh Das, Ming Y Deng, Shawn Babiuk, Michael T McIntosh
Capripoxviruses (CaPVs), consisting of Sheeppox virus (SPV), Goatpox virus (GPV), and Lumpy skin disease virus (LSDV) species, cause economically significant diseases in sheep, goats, and cattle, respectively. Quantitative real-time polymerase chain reaction (qPCR) assays are routinely used for rapid detection of CaPVs in surveillance and outbreak management programs. We further modified and optimized 2 previously published CaPV qPCR assays, referred to as the Balinsky and Bowden assays, by changing commercial PCR reagents used in the tests...
May 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/28419026/the-gas-sampling-interval-effect-on-vo2peak-is-independent-of-exercise-protocol
#4
Cory M Scheadler, Matthew J Garver, Nicholas J Hanson
INTRODUCTION: There is a plethora of gas sampling intervals available during cardiopulmonary exercise (CPX) testing to measure peak oxygen consumption (VO2peak). Different intervals can lead to altered VO2peaks. Whether differences are affected by the exercise protocol or subject sample is not clear. The purpose of this investigation was to determine whether VO2peak differed due to manipulation of sampling intervals and whether differences were independent of the protocol and subject sample...
April 18, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28401230/synthesis-of-layer-like-ni-oh-2-decorated-znin2s4-sub-microspheres-with-enhanced-visible-light-photocatalytic-hydrogen-production-activity
#5
Songsong Li, Dongsheng Dai, Lei Ge, Yangqin Gao, Changcun Han, Nan Xiao
Novel layer-like Ni(OH)2 co-catalyst-decorated ZnIn2S4 microsphere photocatalysts were synthesized for the first time via a facile in situ deposition method to boost the photocatalytic H2-production performance. The physical and optical properties of the as-prepared Ni(OH)2-ZnIn2S4 composite samples were characterized via X-ray diffraction (XRD), transmission electron microscopy (TEM), UV-vis diffusion reflectance spectroscopy (DRS), X-ray photoelectron spectroscopy (XPS), and surface photovoltage spectroscopy (SPV)...
April 12, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28377255/safety-of-superior-petrosal-vein-sacrifice-during-microvascular-decompression-of-the-trigeminal-nerve
#6
Omar N Pathmanaban, Frazer O'Brien, Yahia Z Al-Tamimi, Charlotte L Hamerbeck-Ward, Scott A Rutherford, Andrew T King
BACKGROUND: Microvascular decompression (MVD) is a safe and effective treatment for trigeminal neuralgia (TGN). Cerebellar venous infarction is a complication associated with surgical sacrifice of the superior petrosal vein (SPV). The SPV intervenes between the trigeminal nerve and the surgeon. Optimal exposure of the cisternal trigeminal nerve, particularly at the brain stem, can be achieved by sacrificing the SPV. We analysed a cohort of 224 patients to determine the frequency of cerebellar venous infarction...
April 1, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28321887/simplification-of-visual-rendering-in-simulated-prosthetic-vision-facilitates-navigation
#7
Victor Vergnieux, Marc J-M Macé, Christophe Jouffrais
Visual neuroprostheses are still limited and simulated prosthetic vision (SPV) is used to evaluate potential and forthcoming functionality of these implants. SPV has been used to evaluate the minimum requirement on visual neuroprosthetic characteristics to restore various functions such as reading, objects and face recognition, object grasping, etc. Some of these studies focused on obstacle avoidance but only a few investigated orientation or navigation abilities with prosthetic vision. The resolution of current arrays of electrodes is not sufficient to allow navigation tasks without additional processing of the visual input...
March 21, 2017: Artificial Organs
https://www.readbyqxmd.com/read/28320711/a-novel-hybrid-plasmid-carrying-multiple-antimicrobial-resistance-and-virulence-genes-in-salmonella-dublin
#8
Chand S Mangat, Sadjia Bekal, Rebecca J Irwin, Michael R Mulvey
Virulence plasmids and antibiotic resistance plasmids are usually maintained separately in Salmonella spp., however we report an instance of a hybrid plasmid (pN13-01125) in Salmonella Dublin. The complete sequence of the 172,265 bp plasmid suggested that pN13-01125 is comprised of the previously described pSDVr and pSH696_135 plasmids and that the mechanism of hybridization likely involved IS6 (IS26) insertion sequence elements. The plasmid has a low conjugation frequency, confers resistance to six classes of antimicrobials, and contains a complete spv virulence operon...
March 20, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28290205/directly-probing-charge-separation-at-interface-of-tio2-phase-junction
#9
Yuying Gao, Jian Zhu, Hongyu An, Pengli Yan, Baokun Huang, Ruotian Chen, Fengtao Fan, Can Li
Phase junction is often recognized as an effective strategy to achieve efficient charge separation in photocatalysis and photochemistry. As a crucial factor to determine the photogenerated charges dynamics, there is an increasingly hot debate about the energy band alignment across the interface of phase junction. Herein, we reported the direct measurement of the surface potential profile over the interface of TiO2 phase junction. A built-in electric field up to 1 kV/cm from rutile to anatase nanoparticle was detected by Kelvin Probe Force Microscopy (KPFM)...
March 16, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28275226/prediction-of-fluid-responsiveness-based-on-liver-compression-induced-blood-pressure-changes-in-children-after-cardiac-surgery
#10
Ji-Hyun Lee, In-Kyung Song, Eun-Hee Kim, Hee-Soo Kim, Jin-Tae Kim
BACKGROUND: This study evaluated whether liver compression-induced blood pressure changes can predict fluid responsiveness in children after cardiac surgery. METHODS: Children aged < 5 years who were undergoing cardiac surgery were evaluated after the sternum was closed. Before fluid loading, the right upper abdomen was compressed at a pressure of 30 mmHg for 15 seconds and changes in blood pressure waves were recorded. Then, 10 ml/kg of colloid solution was administered...
March 8, 2017: Minerva Anestesiologica
https://www.readbyqxmd.com/read/28272485/construction-and-immunogenicity-of-a-recombinant-swinepox-virus-expressing-a-multi-epitope-peptide-for-porcine-reproductive-and-respiratory-syndrome-virus
#11
Huixing Lin, Zhe Ma, Xin Hou, Lei Chen, Hongjie Fan
To characterize neutralizing mimotopes, phages were selected from a 12-mer phage display library using three anti-porcine reproductive and respiratory syndrome virus (PRRSV) neutralizing monoclonal antibodies: (1) A1; (2) A2; and (3) A7. Of these, A2 and A7 recognize the mimotope, P2, which contains the SRHDHIH motif, which has conserved consensus sequences from amino acid positions 156 to 161 in the N-terminal ectodomain of GP3. The artificial multi-epitope gene, mp2, was designed by combining three repeats of the mimotope P2...
March 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28260292/-anatomy-and-management-of-superior-petrosal-vein-in-microvascular-decompression-for-trigeminal-neuralgia
#12
Y M Yang, Z W Wang, Z Cui, H Z Jiang, C Sha, Q G Yuan, H W Xie, D M Wang
Objective: To investigate the characteristics of superior petrosal vein (SPV) and its influence on the surgical field in microvascular decompression (MVD) for trigeminal neuralgia (TN), and to analyze the effect of the surgical treatment of SPV on the surgical approach, indication and prognosis. Methods: The clinical data of 280 patients with trigeminal neuralgia between Jan. 2013 and Jun. 2016 were collected, including the trunks and the branches of SPV, intraoperative electrocoagulation status, the surgery outcome and complications...
February 21, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28221382/mechanistic-insights-into-the-photoinduced-charge-carrier-dynamics-of-biobr-cds-nanosheet-heterojunctions-for-photovoltaic-application
#13
Huimin Jia, Beibei Zhang, Weiwei He, Yong Xiang, Zhi Zheng
The rational design of high performance hetero-structure photovoltaic devices requires a full understanding of the photoinduced charge transfer mechanism and kinetics at the interface of heterojunctions. In this paper, we intelligently fabricated p-BiOBr/n-CdS heterojunctions with perfect nanosheet arrays by using a facile successive ionic layer adsorption and reaction and chemical bath deposition methods at low temperature. A BiOBr/CdS heterojunction based solar cell has been fabricated which exhibited enhanced photovoltaic responses...
February 21, 2017: Nanoscale
https://www.readbyqxmd.com/read/28219106/reliability-and-validity-of-a-self-paced-cardiopulmonary-exercise-test-in-post-mi-patients
#14
Lauren Ann Jenkins, Alexis Mauger, Jane Fisher, James Hopker
A self-paced peak oxygen uptake (V̇O2peak) test (SPV) has been shown to produce higher V̇O2peak values compared to standard cardiopulmonary exercise tests (sCPET), but has not been tested on any clinical population. This study aimed to assess the reliability of the SPV in a healthy population (study 1), and the validity and reliability of the SPV in post-myocardial infarction (post-MI) patients (study 2). For study 1, 25 healthy participants completed 3 SPV's. For study 2, 28 post-MI patients completed one sCPET and 2 SPV's...
April 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/28157631/enhanced-photocatalytic-degradation-of-phenol-and-photogenerated-charges-transfer-property-over-bioi-loaded-zno-composites
#15
Jingjing Jiang, Hongtao Wang, Xiaodong Chen, Shuo Li, Tengfeng Xie, Dejun Wang, Yanhong Lin
In this paper, a series of BiOI/ZnO photocatalysts containing various BiOI contents were prepared by a facile two-step synthetic method. The structure and crystal phase, morphology, surface element analysis, optical property of as-prepared samples are measured by X-ray diffraction (XRD), Scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS) and UV-Vis diffuse reflectance spectrometry (DRS). BiOI/ZnO photocatalytic activities of the prepared photocatalysts were evaluated by photocatalytic degradation of phenol under simulated light irradiation...
May 15, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28146151/synthesis-of-novel-coox-decorated-ceo2-hollow-structures-with-an-enhanced-photocatalytic-water-oxidation-performance-under-visible-light-irradiation
#16
Siman Fang, Songsong Li, Lei Ge, Changcun Han, Ping Qiu, Yangqin Gao
Cobalt oxide decorated octahedral ceria hollow structures (CoOx/CeO2) with various contents of CoOx nanoparticles were prepared via a simple chemical impregnation method. The obtained samples were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), high resolution transmission electron microscopy (HRTEM), X-ray photoelectron spectroscopy (XPS), UV-Vis diffuse-reflectance spectroscopy (DRS), surface photovoltage spectroscopy (SPV) and transient photovoltage spectroscopy (TPV)...
February 1, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/27996270/upconversion-triggered-charge-separation-in-polymer-semiconductors
#17
Yu Jin Jang, Eunah Kim, Seonghyeon Ahn, Kyungwha Chung, Jihyeon Kim, Heejun Kim, Huan Wang, Jiseok Lee, Dong-Wook Kim, Dong Ha Kim
Upconversion is a unique optical property that is driven by a sequential photon pumping and generation of higher energy photons in a consecutive manner. The efficiency improvement in photovoltaic devices can be achieved when upconverters are integrated since upconverters contribute to the generation of extra photons. Despite numerous experimental studies confirming the relationship, fundamental explanations for a real contribution of upconversion to photovoltaic efficiency are still in demand. In this respect, we suggest a new approach to visualize the upconversion event in terms of surface photovoltage (SPV) by virtue of Kelvin probe force microscopy (KPFM)...
January 19, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/27942980/age-differences-in-physiological-responses-to-self-paced-and-incremental-formula-see-text-testing
#18
RANDOMIZED CONTROLLED TRIAL
Lauren A Jenkins, Alexis R Mauger, James G Hopker
PURPOSE: A self-paced maximal exercise protocol has demonstrated higher [Formula: see text] values when compared against traditional tests. The aim was to compare physiological responses to this self-paced [Formula: see text] protocol (SPV) in comparison to a traditional ramp [Formula: see text] (RAMP) protocol in young (18-30 years) and old (50-75 years) participants. METHODS: Forty-four participants (22 young; 22 old) completed both protocols in a randomised, counter-balanced, crossover design...
January 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/27922194/pharmacodynamic-response-profiles-of-anxiolytic-and-sedative-drugs
#19
Xia Chen, Freerk Broeyer, Marieke de Kam, Joke Baas, Adam Cohen, Joop van Gerven
AIM: Centrally-acting acutely anxiolytic drugs, such as benzodiazepines, barbiturates and gabapentinoids, affect various central nervous system (CNS) functions, which reflects not only their anxiolytic effects but also neuropsychological side-effects. To validate the pharmacodynamic biomarkers for GABA-ergic anxiolytics, this study determined the pharmacodynamics of two anxiolytics and a nonanxiolytic control, and linked them to their anxiolytic and sedative effects, during an anxiety-challenge study day...
May 2017: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/27864781/isolation-identification-and-high-throughput-screening-of-neutral-lipid-producing-indigenous-microalgae-from-south-african-aquatic-habitats
#20
S T Gumbi, B M Majeke, A O Olaniran, T Mutanda
Exploring indigenous microalgae capable of producing significant amounts of neutral lipids through high-throughput screening is crucial for sustainable biodiesel production. In this study, 31 indigenous microalgal strains were isolated from diverse aquatic habitats in KwaZulu-Natal, South Africa. Eight superior lipid-producing strains were selected for further analysis, based on Nile red fluorescence microscopy screening. The microalgal isolates were identified to belong to the genera Chlorella, Neochloris and Chlamydomonas via morpho-taxonomic and molecular approach by 18S rRNA gene sequencing...
May 2017: Applied Biochemistry and Biotechnology
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