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https://www.readbyqxmd.com/read/29053385/full-scale-horizontal-subsurface-flow-constructed-wetlands-to-treat-domestic-wastewater-by-juncus-acutus-and-cortaderia-selloana
#1
Fulya Aydın Temel, Esin Avcı, Yüksel Ardalı
In the present study, a full scale horizontal subsurface flow constructed wetland was designed, constructed and operated to treat domestic wastewater of Kızılcaören village in Samsun city of Turkey. The total surface area of HSFCW was divided into equal parts. The effects of Juncus acutus L. and Cortaderia selloana (Schult.Schult.f.)Asch.&Graebn. on pollutants removal in HSFCWs were evaluated with the meteorological factors. The average removal efficiencies of J. acutus and C. selloana were determined as 60...
October 20, 2017: International Journal of Phytoremediation
https://www.readbyqxmd.com/read/29053360/habitat-association-predicts-genetic-diversity-and-population-divergence-in-amazonian-birds
#2
Michael G Harvey, Alexandre Aleixo, Camila C Ribas, Robb T Brumfield
The ecological traits of organisms may predict their genetic diversity and population genetic structure and mediate the action of evolutionary processes important for speciation and adaptation. Making these ecological-evolutionary links is difficult because it requires comparable genetic estimates from many species with differing ecologies. In Amazonian birds, habitat association is an important component of ecological diversity. Here, we examine the link between habitat association and genetic parameters using 20 pairs of closely related Amazonian bird species in which one member of the pair occurs primarily in forest edge and floodplains and the other occurs in upland forest interior...
November 2017: American Naturalist
https://www.readbyqxmd.com/read/29053169/whole-body-physiologically-based-modelling-of-beta-blockers-in-the-rat-events-in-tissues-and-plasma-following-an-intravenous-bolus-dose
#3
S Y A Cheung, T Rodgers, L Aarons, I Gueorguieva, G L Dickinson, S Murby, C Brown, B Collins, M Rowland
BACKGROUND AND PURPOSE: Whole body physiologically based pharmacokinetic (PBPK) models have been increasingly applied in drug development to describe kinetic events of therapeutic agents in animals and human. The advantage of such modelling is the ability to incorporate vast amounts of physiological information, such as organ blood flow and volume, to ensure that the model is as close to reality as possible. EXPERIMENTAL APPROACH: Prior PBPK model development of enantiomers of a series of seven racemic betablockers, namely acebutolol, betaxolol, bisoprolol, metoprolol, oxprenolol, pindolol and propranolol, together with S-timolol in rat was based on tissue and blood concentration data at steady state...
October 20, 2017: British Journal of Pharmacology
https://www.readbyqxmd.com/read/29053103/ultrasound-functional-imaging-in-an-i-ex-vivo-i-beating-porcine-heart-platform
#4
Niels J Petterson, Louis S Fixsen, Marcel C M Rutten, Nico H J Pijls, Frans N van de Vosse, Richard G P Lopata
In recent years, novel ultrasound functional imaging (UFI) techniques have been introduced to assess cardiac function by measuring, e.g., cardiac output (CO) and/or myocardial strain. Verification and reproducibility assessment in a realistic setting remain major issues. Simulations and phantoms are often unrealistic, whereas in vivo measurements often lack crucial hemodynamic parameters or ground truth data, or suffer from the large physiological and clinical variation between patients when attempting clinical validation...
October 20, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29052101/effects-of-hydraulic-soil-properties-on-vegetation-pattern-formation-in-sloping-landscapes
#5
Gerardo Severino, Francesco Giannino, Fabrizio Cartení, Stefano Mazzoleni, Daniel M Tartakovsky
Current models of vegetation pattern formation rely on a system of weakly nonlinear reaction-diffusion equations that are coupled by their source terms. While these equations, which are used to describe a spatiotemporal planar evolution of biomass and soil water, qualitatively capture the emergence of various types of vegetation patterns in arid environments, they are phenomenological and have a limited predictive power. We ameliorate these limitations by deriving the vertically averaged Richards' equation to describe flow (as opposed to "diffusion") of water in partially saturated soils...
October 19, 2017: Bulletin of Mathematical Biology
https://www.readbyqxmd.com/read/29051947/pre-steady-state-kinetic-analysis-of-damage-recognition-by-human-single-strand-selective-monofunctional-uracil-dna-glycosylase-smug1
#6
Alexandra A Kuznetsova, Danila A Iakovlev, Inna V Misovets, Alexander A Ishchenko, Murat K Saparbaev, Nikita A Kuznetsov, Olga S Fedorova
In all organisms, DNA glycosylases initiate base excision repair pathways resulting in removal of aberrant bases from DNA. Human SMUG1 belongs to the superfamily of uracil-DNA glycosylases catalyzing the hydrolysis of the N-glycosidic bond of uridine and uridine lesions bearing oxidized groups at C5: 5-hydroxymethyluridine (5hmU), 5-formyluridine (5fU), and 5-hydroxyuridine (5hoU). An apurinic/apyrimidinic (AP) site formed as the product of an N-glycosylase reaction is tightly bound to hSMUG1, thus inhibiting the downstream action of AP-endonuclease APE1...
October 20, 2017: Molecular BioSystems
https://www.readbyqxmd.com/read/29051641/optimization-of-spray-drying-process-parameters-for-tucupi-powder-using-the-response-surface-methodology
#7
Flavia Cristina Seabra Pires, Rosinelson da Silva Pena
A completely randomized 2(3) factorial experimental design was used to optimize the process parameters for obtaining tucupi powder through spray drying. The effects of the process variables [inlet air temperature (IT), feed flow rate (FR), and maltodextrin concentration (MD)] on the product properties [moisture, water activity (aw), hygroscopicity, water absorption index (WAI), water solubility index (WSI), total color difference (ΔE*), and β-carotene content] were studied using the response surface methodology (RSM) and linear perturbation plot...
October 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29050851/validation-of-a-new-device-to-quantify-groundwater-surface-water-exchange
#8
Mackenzie M Cremeans, J F Devlin
Distributions of flow across the groundwater-surface water interface should be expected to be as complex as the geologic deposits associated with stream or lake beds and their underlying aquifers. In these environments, the conventional Darcy-based method of characterizing flow systems (near streams) has significant limitations, including reliance on parameters with high uncertainties (e.g., hydraulic conductivity), the common use of drilled wells in the case of streambank investigations, and potentially lengthy measurement times for aquifer characterization and water level measurements...
August 10, 2017: Journal of Contaminant Hydrology
https://www.readbyqxmd.com/read/29050805/modelling-of-thrombin-generation-under-flow-in-realistic-left-anterior-descending-geometries
#9
Konstantinos P Papadopoulos, Grigoris T Gerotziafas, Manolis Gavaises
Currently there are no available methods for prediction of thrombotic complications in Coronary Artery disease. Additionally, blood coagulation tests are mainly performed in a steady system while coagulation in vivo occurs under flow conditions. In this work, a phenomenological model for coagulation up-to thrombin generation is proposed; the model is mainly based on the results of thrombin generation assays and therefore it can account for the variation of the coagulability that is observed in different individuals...
October 16, 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/29049796/surgical-strategy-for-aortic-arch-reconstruction-after-the-norwood-procedure-based-on-numerical-flow-analysis
#10
Shohei Miyazaki, Kagami Miyaji, Keiichi Itatani, Norihiko Oka, Shinji Goto, Masanori Nakamura, Tadashi Kitamura, Tetsuya Horai, Koichi Sughimoto, Yuki Nakamura, Naoki Yoshimura
OBJECTIVES: Inefficient aortic flow after the Norwood procedure is known to lead to the deterioration of ventricular function due to an increased cardiac workload. To prevent the progression of aortic arch obstruction, arch reconstruction concomitant with second-stage surgery is recommended. The aim of this study was to determine the indications for reconstruction based on numerical simulation and to reveal the morphology that affects the haemodynamic parameters. METHODS: Fifteen patients who underwent the Norwood procedure or arch repair and Damus-Kaye-Stansel anastomosis were enrolled...
October 17, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29049343/a-sequential-monte-carlo-approach-to-gene-expression-deconvolution
#11
Oyetunji E Ogundijo, Xiaodong Wang
High-throughput gene expression data are often obtained from pure or complex (heterogeneous) biological samples. In the latter case, data obtained are a mixture of different cell types and the heterogeneity imposes some difficulties in the analysis of such data. In order to make conclusions on gene expresssion data obtained from heterogeneous samples, methods such as microdissection and flow cytometry have been employed to physically separate the constituting cell types. However, these manual approaches are time consuming when measuring the responses of multiple cell types simultaneously...
2017: PloS One
https://www.readbyqxmd.com/read/29049022/cardiovascular-adaptation-to-hypoxia-and-the-role-of-peripheral-resistance
#12
Andrew S Cowburn, David Macias, Charlotte Summers, Edwin R Chilvers, Randall S Johnson
Systemic vascular pressure in vertebrates is regulated by a range of factors: one key element of control is peripheral resistance in tissue capillary beds. Many aspects of the relationship between central control of vascular flow and peripheral resistance are unclear. An important example of this is the relationship between hypoxic response in individual tissues, and the effect that response has on systemic cardiovascular adaptation to oxygen deprivation. We show here how hypoxic response via the HIF transcription factors in one large vascular bed, that underlying the skin, influences cardiovascular response to hypoxia in mice...
October 19, 2017: ELife
https://www.readbyqxmd.com/read/29048216/thermal-response-to-high-power-holmium-laser-lithotripsy
#13
Ali H Aldoukhi, Khurshid R Ghani, Timothy L Hall, William W Roberts
OBJECTIVES: The aim of this study was to investigate "calyceal" fluid temperature changes during holmium laser activation/lithotripsy using settings up to 40 watt power output with different irrigation flow rates. METHODS: The experimental system consisted of a glass test tube (diameter 10 mm/length 75 mm) filled with deionized water, to mimic a calyx. Real time temperature was recorded using a thermocouple (Physitemp, NJ) positioned 5 mm from the bottom of the tube...
October 19, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/29048110/morphometric-and-morphologic-parameters-of-the-heart-in-healthy-alouatta-guariba-clamitans-cabrera-1940
#14
Murilo Gomes de Soutello Charlier, Maurício Gianfrancesco Filippi, Carolina Hagy Girotto, Vanessa Lanes Ribeiro, Carlos Roberto Teixeira, Maria Lúcia Gomes Lourenço, Luiz Carlos Vulcano
BACKGROUND: This study aimed at assessing the heart function of one neotropical primate (Alouatta guariba clamitans) kept in captivity using radiography, electrocardiogram (ECG) and Doppler echocardiography. METHODS: Ten adult healthy howler monkeys (A. g. clamitans) were evaluated under general anaesthesia. Vertebral Heart Scores (VHS) were obtained from radiographic studies. Ejection fraction, shortening fraction of left ventricle, left atrial/aortic root ratio, ascending aortic diameter, peak velocity of pulmonary, mitral, tricuspid and aortic blood flow and other values were measured by Doppler echocardiography...
October 19, 2017: Journal of Medical Primatology
https://www.readbyqxmd.com/read/29047590/correcting-aero-optical-wavefront-aberration-of-the-supersonic-mixing-layer-based-on-periodic-pulse-forcing
#15
Guangming Guo, Hong Liu
A correction strategy for correcting the aero-optical wavefront aberration of the supersonic mixing layer is presented based on flow control that is implemented by periodic pulse forcing. The flow field of the controlled supersonic mixing layer is simulated by large eddy simulation, and the optical transmission trajectory of the incident beam is computed by the ray-tracing method. The key component of the correction strategy is a compensation signal employed to correct the aberrated wavefront, which is produced according to flow and control parameters...
June 1, 2017: Applied Optics
https://www.readbyqxmd.com/read/29046465/-usefulness-of-bilateral-rso-sub-2-sub-monitoring-for-predicting-cerebral-hyperperfusion-syndrome-after-carotid-artery-stenting
#16
Jun Niimi, Shoichiro Ishihara, Eisuke Tsukagoshi, Hiroaki Neki, Yoshiaki Kakehi, Nahoko Uemiya, Kouji Mizokami, Hideaki Ishihara, Shinya Kohyama, Fumitaka Yamane
OBJECTIVE: Cerebral hyperperfusion syndrome(CHS)and cerebral hyperperfusion phenomenon(CHP)induce intracranial hemorrhage and can become critical complications after carotid artery stenting(CAS). The purpose of the present study was to predict and avoid CHS after CAS using bilateral rSO<sub>2</sub> intraoperative monitoring. METHODS: We retrospectively analyzed 100 consecutive patients who underwent CAS between January 2012 and May 2014 in our institution...
October 2017: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/29045964/-increased-serum-c-c-chemokine-ligand-19-levels-correlated-with-b-cell-abnormalities-in-systemic-lupus-erythematosus
#17
H J Liu, L J Shi, F L Hu, H H Yao, Z G Li, Y Jia
OBJECTIVE: To detect the levels of serum C-C chemokine ligand 19 (CCL19) in patients with systemic lupus erythematosus (SLE) and to evaluate the correlation between CCL19 expression and clinical features and laboratory parameters, trying to reveal the possible role of CCL19 in the pathogenesis of systemic lupus erythematosus. METHODS: The levels of serum CCL19 were measured by enzyme linked immunosorbent assay (ELISA) in 90 patients with SLE and 30 healthy controls...
October 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29045745/long-term-oral-appliance-therapy-improves-daytime-function-and-mood-in-upper-airway-resistance-syndrome-patients
#18
Luciana B M Godoy, Luciana Palombini, Dalva Poyares, Cibele Dal-Fabbro, Thaís Moura Guimarães, Priscila Calixto Klichouvicz, Sergio Tufik, Sonia Maria Togeiro
Objectives: To evaluate the long term effects of an oral appliance on clinical symptoms, respiratory sleep parameters, sleep quality and sustained attention in patients with Upper Airway Resistance Syndrome (UARS) compared with placebo. Methods: This study was a randomized placebo-controlled clinical trial. Thirty UARS patients were randomized in two groups: placebo and mandibular advancement device (MAD) groups. UARS criteria were presence of sleepiness (Epworth Sleepiness Scale ≥ 10) and/or fatigue (Modified Fatigue Impact Scale ≥ 38) associated with an apnea/hypopnea index (AHI) ≤ 5 and a respiratory disturbance index (RDI) > 5 events/hour of sleep, and/or flow limitation in more than 30% of total sleep time...
October 17, 2017: Sleep
https://www.readbyqxmd.com/read/29045422/cluster-analysis-identifies-three-urodynamic-patterns-in-patients-with-orthotopic-neobladder-reconstruction
#19
Kwang Hyun Kim, Hyun Suk Yoon, Wan Song, Hee Jung Choo, Hana Yoon, Woo Sik Chung, Bong Suk Sim, Dong Hyeon Lee
PURPOSE: To classify patients with orthotopic neobladder based on urodynamic parameters using cluster analysis and to characterize the voiding function of each group. MATERIALS AND METHODS: From January 2012 to November 2015, 142 patients with bladder cancer underwent radical cystectomy and Studer neobladder reconstruction at our institute. Of the 142 patients, 103 with complete urodynamic data and information on urinary functional outcomes were included in this study...
2017: PloS One
https://www.readbyqxmd.com/read/29045416/neonatal-immune-response-to-rhinovirus-a16-has-diminished-dendritic-cell-function-and-increased-b-cell-activation
#20
Amanda Barlow-Anacker, Yury Bochkov, James Gern, Christine M Seroogy
BACKGROUND: Rhinovirus infections during infancy account for the majority of respiratory illness health care utilization and are an associated risk factor for subsequent development of allergic asthma. Neonatal type I interferon production is diminished compared to adults after stimulation with TLR agonists. However, broad profiling of immune cell responses to infectious rhinovirus has not been undertaken and we hypothesized that additional immune differences can be identified in neonates...
2017: PloS One
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