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https://www.readbyqxmd.com/read/28642340/cardiovascular-and-cerebral-hemodynamics-during-exercise-and-recovery-in-obese-individuals-as-a-function-of-their-fitness-status
#1
Mathieu Gayda, Gabriel Lapierre, Olivier Dupuy, Sarah Fraser, Louis Bherer, Martin Juneau, Vincent Gremeaux, Anil Nigam
The aim of this study was to compare cardiovascular hemodynamics and cerebral oxygenation/perfusion (COP) during and after maximal incremental exercise in obese individuals according to their aerobic fitness versus age-matched healthy controls (AMHC). Fifty-four middle-aged obese (OB) and 16 AMHC were recruited. Maximal cardiopulmonary function (gas exchange analysis), cardiac hemodynamics (impedance cardiography), and left frontal COP (near-infrared spectroscopy: NIRS) were measured continuously during a maximal incremental ergocycle test...
June 2017: Physiological Reports
https://www.readbyqxmd.com/read/28640773/salivary-mitochondrial-dna-copy-number-is-associated-with-exercise-ventilatory-efficiency
#2
Yang Chen, Helene Z Hill, Gudrun Lange, Michael J Falvo
Chen, Y, Hill, HZ, Lange, G, and Falvo, MJ. Salivary mitochondrial DNA copy number is associated with exercise ventilatory efficiency. J Strength Cond Res 31(7): 2000-2004, 2017-Mitochondrial DNA copy number (mtDNAcn) is an index of mitochondrial content and is responsive to changes in exercise training volume. Therefore, assessment of mtDNAcn may help to optimize exercise prescription and aid in athlete monitoring. Although previous work has assessed mtDNAcn derived from skeletal muscle and blood using invasive approaches, no study has examined salivary mtDNAcn and its relationship with sport performance...
July 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28637880/a-study-comparing-vein-integrity-and-clinical-outcomes-vico-in-open-vein-harvesting-and-two-types-of-endoscopic-vein-harvesting-for-coronary-artery-bypass-grafting-the-vico-randomised-clinical-trial
#3
Bhuvaneswari Krishnamoorthy, William R Critchley, Alexander J Thompson, Katherine Payne, Julie Morris, Rajamiyer V Venkateswaran, Ann L Caress, James E Fildes, Nizar Yonan
Background -Current consensus statements maintain that endoscopic vein harvesting (EVH) should be standard care in coronary artery bypass surgery (CABG) but vein quality and clinical outcomes have been questioned. The Vein Integrity and Clinical Outcome (VICO) trial was designed to assess the impact of different vein harvesting methods on vessel damage and if this contributes to clinical outcomes following CABG. Methods -A single centre, randomised clinical trial of patients undergoing CABG with an internal mammary artery, and with one to four vein grafts were recruited...
June 21, 2017: Circulation
https://www.readbyqxmd.com/read/28609106/in-situ-fabrication-of-defective-conx-single-clusters-on-reduced-graphene-oxide-sheets-with-excellent-electrocatalytic-activity-for-oxygen-reduction
#4
Ting He, Xiaojuan Wang, Huiqiong Wu, Hui Xue, Peng Xue, Jing Ma, Minli Tan, Shuanghua He, Rujuan Shen, Lunzhao Yi, Yi Zhang, Juan Xiang
A facile one-step strategy for anchoring defective CoNx single clusters on partly reduced graphene oxide (RGO) is constructed to significantly improve the catalytic performance of non-noble metal complexes toward oxygen reduction reaction (ORR). Sequent loading with trace amounts of metal-free porphyrin and Co2+ in RGO can dramatically enhance both the half-wave potential and peak current density. Intriguingly, the RGO/P/2Co single cluster exhibits the best ORR catalytic performance with the half-wave potential of 0...
June 13, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28608567/the-effect-of-stress-on-haematologic-response-and-physicochemical-parameters-of-muscle-meat-in-rabbits
#5
V Reséndiz-Cruz, J E Ramírez-Bribiesca, D Mota-Rojas, I Guerrero-Legarreta, R G Cruz-Monterrosa, D Hernandez-Sanchez
Ante-mortem studies of stress in rabbits are few and can potentially impact the haematologic response and physicochemical parameters of muscle meat. The aim of this study was to investigate the induction of stress by transport and simulation at two different times. Two hundred rabbits divided in a similar proportion of male and female were stressed by vehicular transportation and with motion simulation, using a vibration platform. They were divided into five groups: Control (without stress), Stress with Short Transportation (30 min), Stress with Long Transportation (60 min), Stress with Short Vibration Platform (30 min) and Stress with Long Vibration Platform (60 min)...
June 13, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28594806/-a-new-method-of-endoscopic-harvesting-of-the-great-saphenous-vein-in-an-open-system
#6
Iu Iu Vecherskiĭ, V V Zatolokin, K A Petlin, Sh D Akhmedov, V M Shipulin
We examined a total of 246 patients subjected to coronary artery bypass grafting with the use of the great saphenous vein (GSV). The patients were subdivided into two groups. Group One (n=121) patients endured procurement of the great saphenous vein by a new endoscopic technique in an open system with the help of the equipment Karl Storz and electric dissector Ligasure. In Group Two (n=125) patients the vein was harvested by means of the traditional open method. In all patients we evaluated complications in the early postoperative period 13±2...
2017: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/28585973/impact-on-short-lived-climate-forcers-slcfs-from-a-realistic-land-use-change-scenario-via-changes-in-biogenic-emissions
#7
C E Scott, S A Monks, D V Spracklen, S R Arnold, P M Forster, A Rap, K S Carslaw, M P Chipperfield, C L S Reddington, C Wilson
More than one quarter of natural forests have been cleared by humans to make way for other land-uses, with changes to forest cover projected to continue. The climate impact of land-use change (LUC) is dependent upon the relative strength of several biogeophysical and biogeochemical effects. In addition to affecting the surface albedo and exchanging carbon dioxide (CO2) and moisture with the atmosphere, vegetation emits biogenic volatile organic compounds (BVOCs), altering the formation of short-lived climate forcers (SLCFs) including aerosol, ozone (O3) and methane (CH4)...
June 6, 2017: Faraday Discussions
https://www.readbyqxmd.com/read/28576375/testing-commercial-biopreservative-against-spoilage-microorganisms-in-map-packed-ricotta-fresca-cheese
#8
C Spanu, C Scarano, F Piras, V Spanu, C Pala, D Casti, S Lamon, F Cossu, M Ibba, G Nieddu, E P L De Santis
Ricotta fresca cheese is susceptible to secondary contamination and is able to support the growth of pathogens or spoilage psychotrophic bacteria during storage. The aim of the present study was to evaluate which among three commercial biopreservatives was suitable to be used to control the growth of spoilage microorganisms in sheep's milk MAP ricotta fresca cheese. 144 Ricotta fresca cheese samples were inoculated either with the bioprotective culture Lyofast FPR 2 (including Enterococcus faecium, Lactobacillus plantarum e Lactobacillus rhamnosus) or Lyofast CNBAL (Carnobacterium spp) or the fermentate MicroGARD 430...
September 2017: Food Microbiology
https://www.readbyqxmd.com/read/28571240/monitoring-microcirculatory-blood-flow-during-cardiopulmonary-bypass-in-paediatric-cardiac-surgery-patients-as-a-predictor-for-anaerobic-metabolism
#9
Ramesh Patel, Atul Solanki, Hasmukh Patel, Jignesh Patel, Himani Pandya, Jainam Sharma
INTRODUCTION: Improving tissue oxygenation is one of most important tasks in management of low cardiac output. Central venous oxygen saturation (ScvO2) and lactate are established criteria for monitoring the adequacy of tissue oxygenation. The venous-to-arterial carbon dioxide difference [P(v-a)CO2] is inversely associated with cardiac output. AIM: To study the use of P(v-a)CO2/C(a-v)O2 ratio as a marker of low cardiac output during Cardiopulmonary Bypass (CPB) in paediatric cardiac surgical patients...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28560751/differential-control-of-respiratory-frequency-and-tidal-volume-during-high-intensity-interval-training
#10
Andrea Nicolò, Samuele M Marcora, Ilenia Bazzucchi, Massimo Sacchetti
Since respiratory frequency (fR ) has been proposed as a good marker of physical effort, furthering the understanding of how fR is regulated during exercise is of great importance. We manipulated recovery intensity and exercise duration during high-intensity interval training (HIIT) to test the hypothesis that fast inputs (including central command) contribute more than metabolic stimuli to fR regulation. Seven male cyclists performed an incremental test, a 10 min and a 20 min continuous time trial (TT) as preliminary tests...
May 31, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/28503946/fractional-co2-laser-therapy-a-new-challenge-for-vulvovaginal-atrophy-in-postmenopausal-women
#11
G P Siliquini, V Tuninetti, V E Bounous, F Bert, N Biglia
OBJECTIVE: To evaluate the effects of CO2 laser in the treatment of vulvovaginal atrophy (VVA) in postmenopausal women. METHODS: VVA was assessed in 87 postmenopausal women (mean age 58.6 ± 6.9 years) before and after the treatment. The protocol consisted of three monthly treatments and included the treatment of vulva. Subjective measures included VAS (Visual Analog Scale) both for vaginal dryness and dyspareunia; DIVA (Day-by-day Impact of Vaginal Aging); a questionnaire on treatment satisfaction and one about the degree of pain during the procedure...
May 15, 2017: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/28502493/the-effect-of-maximal-vs-submaximal-exertion-on-postprandial-lipid-levels-in-individuals-with-and-without-coronary-heart-disease
#12
David M Aronov, Marina G Bubnova, Natalia V Perova, Alexander N Orekhov, Yuri V Bobryshev
BACKGROUND: Decisions about fat consumption and levels of physical activity are among the everyday choices we make in life and risk of coronary heart disease (CHD) can be affected by those choices. OBJECTIVE: The purpose of this study was to investigate the influence of a standard fat load combined with physical exertion of different intensities on the plasma lipid profile of CHD patients and CHD-free individuals. METHODS: This study looked at the influence of different intensities of physical exercise on postprandial lipid metabolism in 20 healthy men and 36 men with diagnosis of CHD...
March 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/28492385/the-prognostic-value-of-central-venous-to-arterial-co2-difference-arterial-central-venous-o2-difference-ratio-in-septic-shock-patients-with-central-venous-o2-saturation-%C3%A2-80
#13
Huaiwu He, Yun Long, Dawei Liu, Xiaoting Wang, Bo Tang
BACKGROUND: It is a great challenge for physician to assess the relationship between O2 delivery and O2 consumption in septic shock patients with high ScvO2. Recently, the venous-to-arterial CO2 difference/arterial-central venous O2 difference ratio (P(v-a)CO2/C(a-v)O2) has shown potential for reflecting anaerobic metabolism. Therefore, we evaluated the value of using the P(v-a)CO2/C(a-v)O2 ratio to predict mortality and assess anaerobic metabolism in septic shock patients with high ScvO2 (≥ 80%)...
May 10, 2017: Shock
https://www.readbyqxmd.com/read/28455103/transcranial-doppler-ultrasonography-in-the-assessment-of-neurovascular-coupling-responses-to-cognitive-examination-in-healthy-controls-a-feasibility-study
#14
C A L Williams, R B Panerai, T G Robinson, V J Haunton
BACKGROUND: We tested the hypothesis that paradigms from the Addenbrooke's Cognitive Examination (ACE-III), including those that had not been studied using TCD previously (novel) versus those which had been (established), would elicit changes in CBF velocity (CBFv). NEW METHOD: Healthy subjects were studied with bilateral transcranial Doppler (TCD), beat-to-beat blood pressure (Finapres), continuous electrocardiogram (ECG), and end-tidal CO2 (nasal capnography)...
April 26, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28452396/reversible-supracolloidal-self-assembly-of-cobalt-nanoparticles-to-hollow-capsids-and-their-superstructures
#15
Nonappa, Johannes S Haataja, Jaakko V I Timonen, Sami Malola, Peter Engelhardt, Nikolay Houbenov, Manu Lahtinen, Hannu Häkkinen, Olli Ikkala
The synthesis and spontaneous, reversible supracolloidal hydrogen bond-driven self-assembly of cobalt nanoparticles (CoNPs) into hollow shell-like capsids and their directed assembly to higher order superstructures is presented. CoNPs and capsids form in one step upon mixing dicobalt octacarbonyl (Co2 CO8 ) and p-aminobenzoic acid (pABA) in 1,2-dichlorobenzene using heating-up synthesis without additional catalysts or stabilizers. This leads to pABA capped CoNPs (core ca. 5 nm) with a narrow size distribution...
June 1, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28440060/a-practical-approach-in-bioreactor-scale-up-and-process-transfer-using-a-combination-of-constant-p-v-and-vvm-as-the-criterion
#16
Sen Xu, Linda Hoshan, Rubin Jiang, Balrina Gupta, Eric Brodean, Kristin O'Neill, T Craig Seamans, John Bowers, Hao Chen
Bioreactor scale-up is a critical step in the production of therapeutic proteins such as monoclonal antibodies (MAbs). With the scale-up criterion such as similar power input per volume or O2 volumetric mass transfer coefficient (kL a), adequate oxygen supply and cell growth can be largely achieved. However, CO2 stripping in the growth phase is often inadequate. This could cascade down to increased base addition and osmolality, as well as residual lactate increase and compromised production and product quality...
April 25, 2017: Biotechnology Progress
https://www.readbyqxmd.com/read/28435685/quantification-and-physiological-significance-of-the-rightward-shift-of-the-v-slope-during-incremental-cardiopulmonary-exercise-testing
#17
Hirotaka Nishijima, Kazuo Kondo, Kazuya Yonezawa, Hiroki Hashimoto, Masayuki Sakurai
BACKGROUND: Ventilatory anaerobic threshold (VAT) is frequently used as a measure of exercise tolerance, with the V-slope method being the standard; however, this needs to be visually determined. Over the years, we have observed that the V-slope itself often appears to shift rightward before the appearance of the VAT (RtShift: rightward shift of V-slope). This phenomenon has long been known to occur during the first 1-2 min of steady-state exercise and disappears thereafter; it is attributed to CO2 storage, presumably in active muscle...
2017: BMC Sports Science, Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28396262/physiological-and-behavioral-flexibility-to-an-acute-co2-challenge-within-and-between-genotypes-in-rainbow-trout
#18
B Sadoul, N C Friggens, C Valotaire, L Labbé, V Colson, P Prunet, I Leguen
Adaptive capacities, governing the ability of animals to cope with an environmental stressor, have been demonstrated to be strongly dependent upon genetic factors. Two isogenic lines of rainbow trout, previously described for their sensitivity and resilience to an acute confinement challenge, were used in the present study to investigate whether adaptive capacities remain consistent when fish are exposed to a different type of challenge. For this purpose, the effects of a 4-hour hypercapnia (CO2 increase) challenge at concentrations relevant in aquaculture conditions are described for the two isogenic lines...
July 2017: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
https://www.readbyqxmd.com/read/28364680/assessment-of-macro-and-micro-oxygenation-parameters-during-fractional-fluid-infusion-a-pilot-study
#19
Marc-Olivier Fischer, Vincent Bonnet, Emmanuel Lorne, Jean-Yves Lefrant, Olivier Rebet, Benoît Courteille, Charlotte Lemétayer, Jean-Jacques Parienti, Jean-Louis Gérard, Jean-Luc Fellahi, Jean-Luc Hanouz
PURPOSE: The main goal of this study was to assess whether maximal fluid infusion improves both oxygen delivery (DO2) and micro-circulatory parameters during hemodilution. The secondary objective was to assess the ability of baseline micro-circulatory parameters to predict oxygen consumption (VO2) response following fluid infusion. MATERIALS AND METHODS: In a postoperative cardiac ICU, patients received repeated fluid infusion until stroke volume (SV) was maximized...
March 27, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28359891/synthesis-characterization-and-antibacterial-activity-of-hybrid-chitosan-cerium-oxide-nanoparticles-as-a-bionanomaterials
#20
R P Senthilkumar, V Bhuvaneshwari, R Ranjithkumar, S Sathiyavimal, V Malayaman, B Chandarshekar
The hybrid chitosan cerium oxide nanoparticles were prepared for the first time by green chemistry approach using plant leaf extract. The intense peak observed around 292nm in the UV-vis spectrum indicate the formation of cerium oxide nanoparticles. The XRD pattern revealed that the hybrid chitosan-cerium oxide nanoparticles have a polycrystalline structure with cubic fluorite phase. The FTIR spectrum of prepared samples showed the formation of Ce-O bonds and chitosan main chains COC and CO. The FESEM image of hybrid chitosan cerium oxide nanoparticles revealed that the particles are spherical in shape with grains size varying from 23...
March 27, 2017: International Journal of Biological Macromolecules
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