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https://www.readbyqxmd.com/read/29791584/risk-factors-for-early-onset-ventilator-associated-pneumonia-in-aneurysmal-subarachnoid-hemorrhage-patients
#1
J B Cui, Q Q Chen, T T Liu, S J Li
This study aimed to investigate the risk factors related to ventilator-acquired pneumonia (VAP) in aneurysmal subarachnoid hemorrhage (SAH) patients. From January 2011 to December 2015, a single-center retrospective study including 200 SAH patients requiring mechanical ventilation (MV) ≥48 h was performed. The clinical data of these patients were collected and analyzed. The age range of the patients were 41-63 and 72 (36%) were male. The Glasgow coma scale score range was 5-15 and the Simplified Acute Physiology Score II range was 31-52...
2018: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/29791340/design-of-a-delayed-xor-phase-detector-for-an-optical-phase-locked-loop-toward-high-speed-coherent-laser-communication
#2
Yang Liu, Shoufeng Tong, Shuai Chang, Yansong Song, Yan Dong, Xin Zhao, Zhe An, Fuwan Yu
Optical phase-locked loops are an effective detection method in high-speed and long-distance laser communication. Although this method can detect weak signal light and maintain a small bit error rate, it is difficult to perform because identifying the phase difference between the signal light and the local oscillator accurately has always been a technical challenge. Thus, a series of studies is conducted to address this issue. First, a delayed exclusive or gate (XOR) phase detector with multi-level loop compound control is proposed...
May 10, 2018: Applied Optics
https://www.readbyqxmd.com/read/29790833/alterations-in-the-cortical-control-of-standing-posture-during-varying-levels-of-postural-threat-and-task-difficulty
#3
Craig D Tokuno, Martin Keller, Mark Gregory Carpenter, Gonzalo Márquez, Wolfgang Taube
Cortical excitability increases during the performance of more difficult postural tasks. However, it is possible that changes in postural threat associated with more difficult tasks may in itself lead to alterations in the neural strategies underlying postural control. Therefore, the purpose of this study was to examine whether changes in postural threat are responsible for the alterations in corticospinal excitability and short interval intracortical inhibition (SICI) that occur with increasing postural task difficulty...
May 23, 2018: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29790677/predicting-healthcare-outcomes-in-prematurely-born-infants-using-cluster-analysis
#4
Victoria MacBean, Alan Lunt, Simon B Drysdale, Muska N Yarzi, Gerrard F Rafferty, Anne Greenough
AIMS: Prematurely born infants are at high risk of respiratory morbidity following neonatal unit discharge, though prediction of outcomes is challenging. We have tested the hypothesis that cluster analysis would identify discrete groups of prematurely born infants with differing respiratory outcomes during infancy. METHODS: A total of 168 infants (median (IQR) gestational age 33 (31-34) weeks) were recruited in the neonatal period from consecutive births in a tertiary neonatal unit...
May 23, 2018: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29790551/a-porous-nickel-cyclotetraphosphate-nanosheet-as-a-new-acid-stable-electrocatalyst-for-efficient-hydrogen-evolution
#5
Xiong Liu, Bo Wen, Ruiting Guo, Jiashen Meng, Ziang Liu, Wei Yang, Chaojiang Niu, Qi Li, Liqiang Mai
The stability of non-precious metal-based electrocatalysts for the acidic hydrogen evolution reaction (HER) is of great importance. Here, we have used nickel cyclotetraphosphate (Ni2P4O12) nanosheet arrays as a HER electrocatalyst for the first time. The Ni2P4O12 arrays were obtained through a facile low-temperature phosphorylation process and possess superior HER catalytic activities and stability in acid. The Ni2P4O12 delivers a small overpotential of 131.8 mV at -10 mA cm-2 and a low Tafel slope of 47.8 mV dec-1 in 0...
May 23, 2018: Nanoscale
https://www.readbyqxmd.com/read/29790045/basic-red-2-and-methyl-violet-adsorption-by-date-pits-adsorbent-characterization-optimization-by-rsm-and-ccd-equilibrium-and-kinetic-studies
#6
Manel Wakkel, Besma Khiari, Féthi Zagrouba
The potential of raw date pits as a natural, widely available and low-cost agricultural waste has been studied in order to adsorb cationic dyes from an aqueous solution. Date pits were characterized by FTIR, SEM, BET, and XRD analysis. To optimize removal of two industrial dyes, basic red 2 (BR2) and methyl violet (MV), from aqueous solution using date pits, response surface methodology (RSM) is employed. Tests were carried out as per central composite design (CCD) with four input parameters namely contact time, temperature, initial concentration of adsorbate, and pH...
May 22, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29789843/efficient-alkaline-hydrogen-evolution-electrocatalysis-enabled-by-an-amorphous-co-mo-b-film
#7
Zhaomei Sun, Shuai Hao, Xuqiang Ji, Xiangjiang Zheng, Junfeng Xie, Xuemei Li, Bo Tang
An amorphous Co-Mo-B film on a Ti mesh (Co-Mo-B/Ti) is fabricated via one-step electrodeposition exhibiting a dramatically enhanced hydrogen evolution reaction (HER) performance in alkaline media. To attain a current density of 20 mA cm-2, such Co-Mo-B/Ti demands only an overpotential of 110 mV, 190 mV lower than that of the counterpart Co-B/Ti, with strong electrochemical durability to maintain its catalytic activity for at least 32 h.
May 23, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29789569/value-added-transformation-of-ubiquitous-substrates-into-highly-efficient-and-flexible-electrodes-for-water-splitting
#8
Atharva Sahasrabudhe, Harsha Dixit, Rahul Majee, Sayan Bhattacharyya
Herein, we present an innovative approach for transforming commonly available cellulose paper into a flexible and catalytic current collector for overall water splitting. A solution processed soak-and-coat method of electroless plating was used to render a piece of paper conducting by conformably depositing metallic nickel nanoparticles, while still retaining the open macroporous framework. Proof-of-concept paper-electrodes are realized by modifying nickel-paper current collector with model electrocatalysts nickel-iron oxyhydroxide and nickel-molybdenum bimetallic alloy through electrodeposition route...
May 22, 2018: Nature Communications
https://www.readbyqxmd.com/read/29789266/microvascular-volume-in-symptomatic-achilles-tendons-is-associated-with-visa-a-score
#9
S F E Praet, J H Ong, C Purdam, M Welvaert, G Lovell, L Dixon, J E Gaida, J Anglim, S Manzanero, N Vlahovich, D Hughes, G Waddington
OBJECTIVES: The role of neovascularisation in tendinopathy is still poorly understood, potentially due to technical limitations of conventional power Doppler ultrasound. This study aimed to investigate the association between contrast-enhanced ultrasound (CEUS) microvascular volume (MV), Victorian Institute of Sports Assessment-Achilles (VISA-A) scores and intrinsic Achilles tendon tenderness, as well as two different Power Doppler modes. DESIGN: Cross-sectional study...
May 15, 2018: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/29788899/topical-nanostructured-lipid-carrier-based-hydrogel-of-mometasone-furoate-for-the-treatment-of-psoriasis
#10
Navjot Kaur, Kusha Sharma, Neena Bedi
OBJECTIVE: The aim of the present study was to develop and evaluate nanostructured lipid carrier based topical hydrogel of mometasone furoate for the treatment of psoriasis. METHODS: Drug loaded NLCs were successfully developed by microemulsion technique. Pseudo ternary phase diagrams were constructed using different combinations of surfactant and co-surfactants to study the microemulsion existence range. Different compositions were selected from the phase diagram showing maximum microemulsion region and were converted into NLCs by dilution in water (1:20)...
May 22, 2018: Pharmaceutical Nanotechnology
https://www.readbyqxmd.com/read/29788714/negative-capacitance-beyond-ferroelectric-switches
#11
Ashwani Kumar, Premlal Balakrishna Pillai, Xiaoyao Song, Maria De Souza
Negative capacitance transistors are a unique class of switches capable of operation beyond the Boltzmann limit to realise sub-thermionic switching. Until now, the negative capacitance effect has been predominantly attributed to devices employing an unstable insulator with ferroelectric properties, exhibiting a two-well energy landscape, in accordance with Landau theory. The theory and operation of a solid electrolyte Field Effect Transistor (SE-FET) of subthreshold swing less than 60 mV/dec in the absence of a ferroelectric gate dielectric is demonstrated in this work...
May 23, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29788374/presence-of-hpv-apobec-related-minority-variants-in-hpv16-genomes-from-anal-and-cervical-samples-but-not-in-hpv52-and-hpv58
#12
Alice-Andrée Mariaggi, Hélène Péré, Marine Perrier, Benoit Visseaux, Gilles Collin, David Veyer, Quentin Le Hingrat, Valentine Marie Ferré, Véronique Joly, Anne Couvelard, Margot Bucau, Carine Davitian, Diane Descamps, Laurent Abramowitz, Charlotte Charpentier
Background: The aim of this study was to investigate the presence of minority variants (MV) in high-risk Human Papillomavirus types (hrHPV16, HPV52, HPV58) from cervical and anal smears. Methods: Whole HPV genome ultra-deep sequencing (UDS) was performed on cervical and anal smears collected during patients' follow-up. Bioinformatics analyses were performed using Bowtie2® (Geneious®). Results: We assessed 55 HPV16+, 20 HPV52+ and 17 HPV58+ samples, with significant differences in patient characteristics for the two anatomic sites...
May 17, 2018: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29788332/constitutive-interferon-pathway-activation-in-tumors-as-an-efficacy-determinant-following-oncolytic-virotherapy
#13
Cheyne Kurokawa, Ianko D Iankov, S Keith Anderson, Ileana Aderca, Alexey A Leontovich, Matthew J Maurer, Ann L Oberg, Mark A Schroeder, Caterina Giannini, Suzanne M Greiner, Marc A Becker, E Aubrey Thompson, Paul Haluska, Mark E Jentoft, Ian F Parney, S John Weroha, Jin Jen, Jann N Sarkaria, Evanthia Galanis
Background: Attenuated measles virus (MV) strains are promising agents currently being tested against solid tumors or hematologic malignancies in ongoing phase I and II clinical trials; factors determining oncolytic virotherapy success remain poorly understood, however. Methods: We performed RNA sequencing and gene set enrichment analysis to identify pathways differentially activated in MV-resistant (n = 3) and -permissive (n = 2) tumors derived from resected human glioblastoma (GBM) specimens and propagated as xenografts (PDX)...
May 16, 2018: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/29787248/efficient-n-doping-and-hole-blocking-in-single-walled-carbon-nanotube-transistors-with-1-2-4-5-tetrakis-tetramethyl-guanidino-benzene
#14
Severin Schneider, Maximilian Brohmann, Roxana Lorenz, Yvonne J Hofstetter, Marcel Rother, Eric Sauter, Michael Zharnikov, Yana Vaynzof, Hans-Joerg Himmel, Jana Zaumseil
Efficient, stable and solution-based n-doping of semiconducting single-walled carbon nanotubes (SWCNTs) is highly desired for complementary circuits but remains a significant challenge. Here we present 1,2,4,5-tetrakis(tetramethyl-guanidino)benzene (ttmgb) as a strong two-electron donor that enables the fabrication of purely n-type SWCNT field-effect transistors (FETs). We apply ttmgb to networks of monochiral, semiconducting (6,5) SWCNTs that show intrinsic ambipolar behavior in bottom-contact/top-gate FETs and obtain unipolar n-type transport with 3 to 5 fold enhancement of electron mobilities (approx...
May 22, 2018: ACS Nano
https://www.readbyqxmd.com/read/29786972/a-lyophilized-and-thermal-two-step-synthesis-of-cofe-alloy-nanoparticles-embedded-in-n-doped-carbon-nanosheets-carbon-nanotubes-for-highly-efficient-oxygen-evolution-reaction
#15
Yang Liu, Feng Li, Haidong Yang, Jing Li, Ping Ma, Yan Zhu, Jiantai Ma
There is a vital need to explore highly-efficient and stable nonprecious-metal catalysts for oxygen evolution reaction (OER) to reduce the overpotential and further improve the energy conversion efficiency. Herein, we report a unique and cost-effective lyophilized and thermal two step procedure to synthesize high-performance CoFe alloy nanoparticles embedded in N-doped carbon nanosheets interspersed with carbon nanotubes (CoFe-N-CN/CNTs) hybrid. The lyophilization step during catalysts preparation is beneficial to uniform the dispersion of carbon-like precursors and avoid the agglomeration of metal particles...
May 22, 2018: ChemSusChem
https://www.readbyqxmd.com/read/29786733/a-facet-controlled-rh-3-pb-2-s-2-nanocage-as-an-efficient-and-robust-electrocatalyst-toward-the-hydrogen-evolution-reaction
#16
Taekyung Kim, Jongsik Park, Haneul Jin, Aram Oh, Hionsuck Baik, Sang Hoon Joo, Kwangyeol Lee
Highly active and durable electrocatalysts for the hydrogen evolution reaction (HER) may play a pivotal role in commercial success of electrolytic water splitting technology. Among various material classes, binary metal sulphides show a great promise as HER catalysts because of their tunable energy levels conducive to a high catalytic activity and high robustness under harsh operating conditions. On the other hand, facet-controlled nanoparticles with controlled surface energies have gained great recent popularity as active and selective catalysts...
May 22, 2018: Nanoscale
https://www.readbyqxmd.com/read/29786728/selenization-of-nimn-layered-double-hydroxide-with-enhanced-electrocatalytic-activity-for-oxygen-evolution
#17
Jing Du, Zehua Zou, Ailing Yu, Cailing Xu
Exploiting highly active oxygen evolution reaction electrocatalysts is of great importance in the cost-effective generation of clean fuels. Herein, the preparation of NiMn-layered double hydroxide with selenization is adopted to reduce the charge transfer resistance of the electrocatalytic oxygen evolution reaction and enhance electrocatalytic performance. As a result, this selenization product of NiMn-layered double hydroxide can reach a current density of 10 mA cm-2 at a low overpotential of 280 mV on glassy carbon electrode in 1...
May 22, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29786642/determining-the-radiation-enhancement-effects-of-gold-nanoparticles-in-cells-in-a-combined-treatment-with-cisplatin-and-radiation-at-therapeutic-megavoltage-energies
#18
Celina Yang, Kyle Bromma, Wonmo Sung, Jan Schuemann, Devika Chithrani
Combined use of chemotherapy and radiation therapy is commonly used in cancer treatment, but the toxic effects on normal tissue are a major limitation. This study assesses the potential to improve radiation therapy when combining gold nanoparticle (GNP) mediated radiation sensitization with chemoradiation compared to chemoradiation alone. Incorporation of GNPs with 2 Gy, 6 MV (megavoltage) radiation resulted in a 19 ± 6% decrease in survival of MDA-MB-231 cells. Monte-Carlo simulations were performed to assess dosimetric differences in the presence of GNPs in radiation...
May 22, 2018: Cancers
https://www.readbyqxmd.com/read/29786612/a-formalism-for-reference-dosimetry-in-photon-beams-in-the-presence-of-a-magnetic-field
#19
Bram van Asselen, Simon J Woodings, Sara L Hackett, Theo L van Soest, Jan G M Kok, Bas W Raaymakers, Jochem W H Wolthaus
A generic formalism is proposed for reference dosimetry in the presence of a magnetic field. Besides the regular correction factors from the conventional reference dosimetry formalisms, two factors are used to take into account magnetic field effects: 1) a dose conversion factor to correct for the change in local dose distribution and 2) a correction of the reading of the dosimeter used for the reference dosimetry measurements. The formalism was applied to the Elekta MRI-Linac, for which the 1.5 T magnetic field is orthogonal to the 7 MV photon beam...
May 22, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29786168/variation-in-electrode-redox-potential-selects-for-different-microorganisms-under-cathodic-current-flow-from-electrodes-in-marine-sediments
#20
Bonita R Lam, Annette R Rowe, Kenneth H Nealson
Extracellular electron transport (EET) is a microbial process that allows microorganisms to transport electrons to and from insoluble substrates outside of the cell. Although progress has been made in understanding how microbes transfer electrons to insoluble substrates, the process of receiving electrons has largely remained unexplored. We investigated redox potentials favorable for donating electrons to dissolved and insoluble components in Catalina Harbor marine sediment by combining electrochemical techniques with geochemistry and molecular methods...
May 22, 2018: Environmental Microbiology
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