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https://www.readbyqxmd.com/read/28345167/a-dynamic-estimation-of-obesity-using-nhanes-data-a-pseudo-panel-approach
#1
Michelle Saksena, Norman Maldonado
In this analysis, we examine the effect of wages on obesity by constructing pseudo-panels to conduct a dynamic estimation of Grossman's human capital model. The results indicate that wages have an increasing effect on obesity status. After accounting for past health status, the protective effect of wages commonly disseminated in the literature reverses on obesity status. The results may also indicate possible asymmetric consumption behavior between foods/nutrients that improve diet quality versus those that degrade it...
March 27, 2017: Health Economics
https://www.readbyqxmd.com/read/28343951/orthopedic-in-training-examination-a-performance-review-based-on-program-and-resident-specific-characteristics
#2
Christopher L Camp, Ryan M Degen, Norman S Turner, Arlen D Hanssen, Matthew D Karam, Joshua S Dines
OBJECTIVES: The orthopedic in-training examination (OITE) is the most common and objective method used to assess resident knowledge in the United States. As such, residents and programs use a number of strategies to maximize OITE performance. The purpose of this work was to better understand what strategies were being implemented and to determine which program-specific and resident-specific characteristics best correlate with improved scores. DESIGN: A national survey of orthopedic residents and program directors (PDs) was performed to better understand OITE performance and correlate scores with various test preparation strategies...
March 23, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28343851/somatosensory-rehabilitation-for-allodynia-in-complex-regional-pain-syndrome-of-the-upper-limb-a-retrospective-cohort-study
#3
Tara L Packham, Claude J Spicher, Joy C MacDermid, Susan Michlovitz, D Norman Buckley
STUDY DESIGN: Retrospective cohort study. INTRODUCTION: Somatosensory rehabilitation is a standardized method of evaluation and conservative treatment of painful disorders of vibrotactile sensation, including the mechanical allodynia and burning pain of complex regional pain syndrome (CRPS). PURPOSE OF THE STUDY: The purpose of this study was to examine the effectiveness of somatosensory rehabilitation for reducing allodynia in persons with CRPS of 1 upper limb in a retrospective consecutive cohort of patients...
March 23, 2017: Journal of Hand Therapy: Official Journal of the American Society of Hand Therapists
https://www.readbyqxmd.com/read/28343822/the-new-surgical-technique-for-improving-total-knee-and-hip-arthroplasty-outcomes-patient-selection
#4
Kevin Magone, Bernard P Kemker, Nataliya Pilipenko, Erin O'Connor, Norman Walter, Theresa Atkinson
BACKGROUND: Inclusion of patient satisfaction scores in setting reimbursements has been suggested by health care policy makers to contain cost and improve outcomes. The Short Form 36 Health Survey (SF-36) score provides a health-related quality of life (HRQoL) measure of arthroplasty outcome. Although previous work identified factors that influence this score for hip and knee arthroplasty patients, they did not focus on how a surgeon might use this information in a clinical setting. The present study examined whether relatively simple criteria might identify patients more likely to experience minimal HRQoL improvement...
March 1, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28342300/hypofractionated-re-irradiation-to-the-brainstem-in-children-with-recurrent-brain-tumors
#5
Timothy V Waxweiler, Arya Amini, Yevgeniy Vinogradskiy, Norman Yeh, Nicholas K Foreman, Todd C Hankinson, Arthur K Liu
To characterize radiation necrosis following hypofractionated brainstem re-irradiation in pediatric patients, we reviewed 23 cases with 28 tumors invading or abutting brainstem and treated with hypofractionated re-irradiation from 2004 to 2014. Re-irradiation delivered total doses of 16-30 Gy in two to five fractions. The most commons regimens used were 24 Gy in three fractions and 25 Gy in five fractions. At median follow-up of 12.8 months, median overall survival was 14.7 months and eight in-field recurrences were detected (median time 10...
May 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28342279/learning-effect-on-perinatal-post-mortem-magnetic-resonance-imaging-reporting-single-reporter-diagnostic-accuracy-of-200-cases
#6
Clare Ashwin, J Ciaran Hutchinson, Xin Kang, Dean Langan, Rod Jones, Wendy Norman, Mieke Cannie, Jacques Jani, Neil J Sebire, Owen J Arthurs
OBJECTIVES: To compare diagnostic accuracy of perinatal post mortem magnetic resonance imaging (PMMR) against conventional autopsy, when reported by a single blinded observer for all organ systems following a period of initial experience. METHODS: We compared pre-autopsy PMMR to conventional autopsy for the detection of: (a) major pathological abnormalities related to the cause of death; and (b) all diagnostic findings in five different body organ systems. PMMR was reported blinded to autopsy findings...
March 25, 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/28342214/real-time-fmri-neurofeedback-in-adolescents-with-attention-deficit-hyperactivity-disorder
#7
Analucia A Alegria, Melanie Wulff, Helen Brinson, Gareth J Barker, Luke J Norman, Daniel Brandeis, Daniel Stahl, Anthony S David, Eric Taylor, Vincent Giampietro, Katya Rubia
Attention Deficit Hyperactivity Disorder (ADHD) is associated with poor self-control, underpinned by inferior fronto-striatal deficits. Real-time functional magnetic resonance neurofeedback (rtfMRI-NF) allows participants to gain self-control over dysregulated brain regions. Despite evidence for beneficial effects of electrophysiological-NF on ADHD symptoms, no study has applied the spatially superior rtfMRI-NF neurotherapy to ADHD. A randomized controlled trial tested the efficacy of rtfMRI-NF of right inferior prefrontal cortex (rIFG), a key region that is compromised in ADHD and upregulated with psychostimulants, on improvement of ADHD symptoms, cognition, and inhibitory fMRI activation...
March 25, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28341922/have-admissions-committees-considered-all-the-evidence
#8
EDITORIAL
Kent Hecker, Geoff Norman
No abstract text is available yet for this article.
May 2017: Advances in Health Sciences Education: Theory and Practice
https://www.readbyqxmd.com/read/28341723/supervisor-descriptions-of-veterinary-student-performance-in-the-clinical-workplace-a-qualitative-interview-study
#9
E J Norman
This qualitative study investigated the qualities of veterinary student performance that inform a supervisor's impression of their competency. Semi-structured interviews were conducted with a purposive sample of 15 supervisors from different veterinary subdisciplines, to elicit descriptions of excellent, weak and marginal students. Thematic analysis of transcriptions revealed 12 themes, of which engagement was frequently discussed and of stated importance, and trustworthiness was a differentiator of weak and marginal students from excellent students...
March 24, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28341675/investigating-enterobius-vermicularis-as-a-novel-surrogate-of-helminth-ova-presence-in-tertiary-wastewater-treatment-plants
#10
Sydney P Rudko, Norma J Ruecker, Nicholas J Ashbolt, Norman F Neumann, Patrick C Hanington
Significant effort has gone into assessing the fate and removal of viruses, bacteria and protozoan parasites during wastewater treatment to provide data addressing potential health risks associated with reuse options. Comparatively less is known about the fate of parasitic worm ova species in these complex systems. It is largely assumed that these helminths settle and are removed with the sludge, and consequently represent a relatively low risk for wastewater reuse applications. However, helminths are a highly diverse group of organisms that display a wide range of physical properties that complicate the application of a single performance expectation for helminth reduction during wastewater treatment...
March 24, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28341622/abortion-care-in-canada-is-decided-between-a-woman-and-her-doctor-without-recourse-to-criminal-law
#11
W V Norman, J Downie
No abstract text is available yet for this article.
March 24, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28337638/erratum-to-using-a-discrete-choice-experiment-to-value-the-qlu-c10d-feasibility-and-sensitivity-to-presentation-format
#12
R Norman, R Viney, N K Aaronson, J E Brazier, D Cella, D S J Costa, P M Fayers, G Kemmler, S Peacock, A S Pickard, D Rowen, D J Street, G Velikova, T A Young, M T King
No abstract text is available yet for this article.
March 23, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28337321/prototypic-18-f-labeled-argininamide-type-neuropeptide-y-y1r-antagonists-as-tracers-for-pet-imaging-of-mammary-carcinoma
#13
Max Keller, Simone Maschauer, Albert Brennauer, Philipp Tripal, Norman Koglin, Ralf Dittrich, Günther Bernhardt, Torsten Kuwert, Hans-Jürgen Wester, Armin Buschauer, Olaf Prante
The neuropeptide Y (NPY) Y1 receptor (Y1R) selective radioligand (R)-N(α)-(2,2-diphenylacetyl)-N(ω)-[4-(2-[(18)F]fluoropropanoylamino)butyl]aminocarbonyl-N-(4-hydroxybenzyl)argininamide ([(18)F]23), derived from the high-affinity Y1R antagonist BIBP3226, was developed for imaging studies of Y1R-positive tumors. Starting from the argininamide core bearing amine-functionalized spacer moieties, a series of fluoropropanoylated and fluorobenzoylated derivatives was synthesized and studied for Y1R affinity. The fluoropropanoylated derivative 23 displayed high affinity (Ki = 1...
March 9, 2017: ACS Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28336297/home-based-telerehabilitation-is-not-inferior-to-a-centre-based-program-in-patients-with-chronic-heart-failure-a-randomised-trial
#14
Rita Hwang, Jared Bruning, Norman R Morris, Allison Mandrusiak, Trevor Russell
QUESTION: Is a 12-week, home-based telerehabilitation program conducted in small groups non-inferior to a traditional centre-based program in terms of the change in 6-minute walk distance? Is the telerehabilitation program also non-inferior to a centre-based program in terms of functional capacity, muscle strength, quality of life, urinary incontinence, patient satisfaction, attendance rates, and adverse events? DESIGN: Randomised, parallel, non-inferiority trial with concealed allocation, intention-to-treat analysis and assessor blinding...
March 14, 2017: Journal of Physiotherapy
https://www.readbyqxmd.com/read/28335606/isolation-and-identification-of-the-novel-tubulin-polymerization-inhibitor-bifidenone
#15
Russell B Williams, Steven M Martin, Julie A Lawrence, Vanessa L Norman, Mark O'Neil-Johnson, Gary R Eldridge, Courtney M Starks
The pursuit of structurally novel compounds has led to the isolation of a series of neolignans (2-6), for which the structures have been determined from microgram quantities using microcryoprobe NMR technology. Compounds 2-6 provided some unexpectedly clear structure-activity relationship data, with compound 2 demonstrating significantly more potency in the in vitro cytotoxicity assay than the other analogues. Further screening found that compound 2 induces apoptosis with activation of caspase 3/7. The NCI Compare algorithm suggested that compound 2 acts through the inhibition of tubulin/microtubule dynamics...
March 24, 2017: Journal of Natural Products
https://www.readbyqxmd.com/read/28334999/rewiring-the-primary-somatosensory-cortex-in-carpal-tunnel-syndrome-with-acupuncture
#16
Yumi Maeda, Hyungjun Kim, Norman Kettner, Jieun Kim, Stephen Cina, Cristina Malatesta, Jessica Gerber, Claire McManus, Rebecca Ong-Sutherland, Pia Mezzacappa, Alexandra Libby, Ishtiaq Mawla, Leslie R Morse, Ted J Kaptchuk, Joseph Audette, Vitaly Napadow
Carpal tunnel syndrome is the most common entrapment neuropathy, affecting the median nerve at the wrist. Acupuncture is a minimally-invasive and conservative therapeutic option, and while rooted in a complex practice ritual, acupuncture overlaps significantly with many conventional peripherally-focused neuromodulatory therapies. However, the neurophysiological mechanisms by which acupuncture impacts accepted subjective/psychological and objective/physiological outcomes are not well understood. Eligible patients (n = 80, 65 female, age: 49...
March 2, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28333279/inhibition-of-pim1-kinase-attenuates-inflammation-induced-pro-labour-mediators-in-human-fetal-membranes-in-vitro
#17
Ratana Lim, Gillian Barker, Martha Lappas
STUDY QUESTION: Does proviral integration site for Moloney murine leukemic virus (PIM)1 kinase play a role in regulating the inflammatory processes of human labour and delivery? SUMMARY ANSWER: PIM1 kinase plays a critical role in fetal membranes in regulating pro-inflammatory and pro-labour mediators. WHAT IS KNOWN ALREADY: Infection and inflammation have strong causal links to preterm delivery by stimulating pro-inflammatory cytokines and collagen degrading enzymes, which can lead to rupture of membranes...
March 9, 2017: Molecular Human Reproduction
https://www.readbyqxmd.com/read/28332978/structural-reorganization-of-the-chromatin-remodeling-enzyme-chd1-upon-engagement-with-nucleosomes
#18
Ramasubramanian Sundaramoorthy, Amanda L Hughes, Vijender Singh, Nicola Wiechens, Daniel P Ryan, Hassane El-Mkami, Maxim Petoukhov, Dmitri I Svergun, Barbara Treutlein, Salina Quack, Monika Fischer, Jens Michaelis, Bettina Böttcher, David G Norman, Tom Owen-Hughes
The yeast Chd1 protein acts to position nucleosomes across genomes. Here we model the structure of the Chd1 protein in solution and when bound to nucleosomes. In the apo state the DNA binding domain contacts the edge of the nucleosome while in the presence of the non-hydrolyzable ATP analog, ADP-beryllium fluoride, we observe additional interactions between the ATPase domain and the adjacent DNA gyre 1.5 helical turns from the dyad axis of symmetry. Binding in this conformation involves unravelling the outer turn of nucleosomal DNA and requires substantial reorientation of the DNA binding domain with respect to the ATPase domains...
March 23, 2017: ELife
https://www.readbyqxmd.com/read/28332940/longitudinal-cancer-risk-management-trajectories-of-brca1-2-mutation-positive-reproductive-age-women
#19
Jennifer Louise Young, Allison Werner-Lin, Rebecca Mueller, Lindsey Hoskins, Norman Epstein, Mark H Greene
Young women with BRCA1/2 mutations face difficult health-care decisions regarding family formation, fertility, breastfeeding, and whether/when to undergo cancer risk-reducing surgery. This longitudinal qualitative study investigated these life choices during the reproductive years. We conducted two semistructured interviews over three years with 12 reproductive-age BRCA1/2-positive women. Researchers coded transcripts to examine the evolution of risk perceptions, risk management, and family planning decisions...
February 14, 2017: Journal of Psychosocial Oncology
https://www.readbyqxmd.com/read/28332564/pupillary-responses-in-non-proliferative-diabetic-retinopathy
#20
Jason C Park, Yi-Fan Chen, Norman P Blair, Felix Y Chau, Jennifer I Lim, Yannek I Leiderman, Mahnaz Shahidi, J Jason McAnany
The goal of this study was to determine the extent of rod-, cone-, and melanopsin-mediated pupillary light reflex (PLR) abnormalities in diabetic patients who have non-proliferative diabetic retinopathy (NPDR). Fifty diabetic subjects who have different stages of NPDR and 25 age-equivalent, non-diabetic controls participated. PLRs were measured in response to full-field, brief-flash stimuli under conditions that target the rod, cone, and intrinsically-photosensitive (melanopsin) retinal ganglion cell pathways...
March 23, 2017: Scientific Reports
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