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https://www.readbyqxmd.com/read/29222206/catastrophic-catheter-induced-coronary-artery-vasospasm-successfully-rescued-using-intravascular-ultrasound-imaging-guidance
#1
Masaki Kodaira, Ryota Tabei, Toshiki Kuno, Yohei Numasawa
A 46-year-old man underwent coronary angiography for stable angina. He developed inferior ST-segment myocardial infarction during the angiography. Intravascular ultrasound (IVUS) findings suggested coronary vasospasm. Intracoronary administration of isosorbide dinitrate restored the coronary flow. This case illustrates the essential role IVUS imaging played in establishing the diagnosis of catheter-induced coronary vasospasm.
December 7, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29221959/robotically-assisted-percutaneous-coronary-intervention-reasons-for-partial-manual-assistance-or-manual-conversion
#2
Jonathan Harrison, Lawrence Ang, Jesse Naghi, Omid Behnamfar, Ali Pourdjabbar, Mitul P Patel, Ryan R Reeves, Ehtisham Mahmud
BACKGROUND: Robotically-assisted percutaneous coronary intervention (R-PCI) is feasible for simple coronary lesions. OBJECTIVES: To determine the frequency and reasons for partial manual assistance or manual conversion during R-PCI in clinical practice. METHODS: The CorPath 200 System (Corindus, Waltham, MA) enables the operator to sit in a radiation-shielded cockpit and remotely control intracoronary devices including guidewires, balloons, and stents...
November 9, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29216999/characteristics-predictors-and-mechanisms-of-thrombosis-in%C3%A2-coronary-bioresorbable-scaffolds-differences-between-early-and-late-events
#3
Tommaso Gori, Melissa Weissner, Svenja Gönner, Franziska Wendling, Helen Ullrich, Stephen Ellis, Remzi Anadol, Alberto Polimeni, Thomas Münzel
OBJECTIVES: The study sought to investigate the incidence, characteristics, predictors, and possible mechanisms of early and 3-year coronary scaffold thrombosis (ScT). BACKGROUND: An increased incidence of both early and late ScT has been shown in randomized trials. METHODS: Consecutive patients were enrolled in a single-center registry. Quantitative coronary angiography was performed. Incidence and predictors of ScT were assessed with Kaplan-Meier and Cox regression analyses...
December 11, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29215470/invasive-assessment-of-microvascular-function-in-patients-with-valvular-heart-disease
#4
Takeshi Nishi, Hideki Kitahara, Saito Yuichi, Tomoko Nishi, Takashi Nakayama, Yoshihide Fujimoto, Goro Matsumiya, Yoshio Kobayashi
BACKGROUND: The aim of this study was to investigate microvascular function in patients with valvular heart disease (VHD), which causes chronic left ventricular volume and/or pressure overload, therefore change in coronary microvascular hemodynamics. PATIENTS AND METHODS: We prospectively enrolled 30 patients with VHD considered for surgery (10 aortic stenosis, 12 aortic regurgitation, and eight mitral regurgitation) and 30 controls. Intracoronary physiological assessments were performed in the unobstructed left anterior descending artery using a pressure-temperature sensor guidewire at rest and hyperemia...
December 5, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/29212544/plaque-volume-and-plaque-risk-profile-in-diabetic-vs-non-diabetic-patients-undergoing-lipid-lowering-therapy-a-study-based-on-3d-intravascular-ultrasound-and-virtual-histology
#5
Tomas Kovarnik, Zhi Chen, Gary S Mintz, Andreas Wahle, Kristyna Bayerova, Ales Kral, Martin Chval, Karel Kopriva, John Lopez, Milan Sonka, Ales Linhart
BACKGROUND: Coronary atherosclerosis progresses faster in patients with diabetes mellitus (DM) and causes higher morbidity and mortality in such patients compared to non-diabetics ones (non-DM). We quantify changes in plaque volume and plaque phenotype during lipid-lowering therapy in DM versus non-DM patients using advanced intracoronary imaging. METHODS: We analyzed data from 61 patients with stable angina pectoris included to the PREDICT trial searching for prediction of plaque changes during intensive lipid-lowering therapy (40 mg rosuvastatin daily)...
December 7, 2017: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/29207367/subadventitial-advancement-of-a-mother-and-child-catheter-to-allow-successful-recanalization-of-a-complex-in-stent-chronic-total-occlusion-testing-the-resistance-of-the-adventitia
#6
Luciano Candilio, Satoru Mitomo, Mauro Carlino, Antonio Colombo, Lorenzo Azzalini
In-stent chronic total occlusion (CTO) represents a challenging lesion subset for percutaneous coronary intervention (PCI), and although a true-to-true lumen crossing is the first-line strategy, a subadventitial approach may become necessary. Here we describe a case of successful in-stent right coronary artery CTO-PCI performed with subadventitial crossing, crushing of the occluded stents, and advancement of a mother-and-child catheter to the distal right coronary artery through the subadventitial space to allow stent delivery...
December 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29206745/cardiosphere-derived-cells-and-ischemic-heart-failure
#7
Carmel Ashur, William H Frishman
After a myocardial infarction, heart tissue becomes irreversibly damaged, leading to scar formation and inevitably ischemic heart failure. Of the many available interventions after a myocardial infarction, such as percutaneous intervention or pharmacological optimization, none can reverse the ischemic insult on the heart and restore cardiac function. Thus, the only available cure for patients with scarred myocardium is allogeneic heart transplantation, which comes with extensive costs, risks, and complications...
January 2018: Cardiology in Review
https://www.readbyqxmd.com/read/29206694/diagnosis-and-management-of-a-patient-with-recurrent-variant-angina-and-history-of-percutaneous-coronary-intervention-vasospasm-and-percutaneous-coronary-intervention
#8
Massimo Fineschi, Flavio D'Ascenzi, Vasile Sirbu, Sergio Mondillo, Carlo Pierli
No abstract text is available yet for this article.
January 2018: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/29203209/comparative-efficacy-of-two-paclitaxel-coated-balloons-with-different-excipient-coatings-in-patients-with-coronary-in-stent-restenosis-a-pooled-analysis-of-the-intracoronary-stenting-and-angiographic-results-optimizing-treatment-of-drug-eluting-stent-in-stent
#9
Roisin Colleran, Michael Joner, Sebastian Kufner, Felix Altevogt, Franz-Josef Neumann, Mohamed Abdel-Wahab, Janika Bohner, Christian Valina, Gert Richardt, Bernhard Zrenner, Salvatore Cassese, Tareq Ibrahim, Karl-Ludwig Laugwitz, Heribert Schunkert, Adnan Kastrati, Robert A Byrne
BACKGROUND: Angioplasty with paclitaxel-coated balloons (PCB) is recommended for treatment of patients with coronary in-stent restenosis (ISR) according to European clinical practice guidelines. Most clinical trials have investigated iopromide-based PCB and there is a paucity of data comparing efficacy against butyryl-tri-hexyl citrate (BTHC)-based PCB. Our aim was to compare the performance of two widely-used PCB in the treatment of coronary ISR. METHODS: We analysed patients treated with BTHC- or iopromide-PCB for treatment of drug-eluting stent ISR in the setting of 2 consecutive trials with identical inclusion and exclusion criteria...
November 28, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29195505/type-2-diabetes-mellitus-is-associated-with-a-lower-fibrous-cap-thickness-but-has-no-impact-on-calcification-morphology-an-intracoronary-optical-coherence-tomography-study
#10
Andrea Milzi, Mathias Burgmaier, Kathrin Burgmaier, Martin Hellmich, Nikolaus Marx, Sebastian Reith
BACKGROUND: Patients with type 2 diabetes (T2DM) are at high risk for cardiovascular events, which usually arise from the rupture of a vulnerable coronary plaque. The minimal fibrous cap thickness (FCT) overlying a necrotic lipid core is an established predictor for plaque rupture. Recently, coronary calcification has emerged as a relevant feature of plaque vulnerability. However, the impact of T2DM on these morphological plaque parameters is largely unexplored. Therefore, this study aimed to compare differences of coronary plaque morphology in patients with and without T2DM with a particular focus on coronary calcification...
December 1, 2017: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/29182940/clinical-study-of-optical-coherence-tomography-in-the-diagnosis-of-peripheral-pulmonary-artery-thrombus
#11
Cheng Hong, Fu-Quan Luo, Chun-Li Liu, Nan-Shan Zhong, Jie-Ying Li, Wei Wang
BACKGROUND: Peripheral pulmonary artery thrombus (PPT) is common in the clinic. However, due to the lack of an ideal diagnostic tool, PPT cannot be quickly diagnosed and effectively treated at present. Optical coherence tomography (OCT) is a new intravascular imaging technique that is characterized by high image resolution. This technique is suitable for small vessel imaging and has the ability to distinguish red and white thrombi. OBJECTIVE: This study aimed to evaluate the value of OCT in the diagnosis of PPT and in identifying the nature of thrombi by comparing the difference in sensitivity between OCT and selective pulmonary angiography (SPA)...
October 28, 2017: Thrombosis Research
https://www.readbyqxmd.com/read/29174825/when-intravascular-ultrasound-becomes-indispensable-in-percutaneous-coronary-intervention-of-a-chronic-total-occlusion
#12
REVIEW
Mohsen Mohandes, Hugo Vinhas, Francisco Fernández, Cristina Moreno, Mauricio Torres, Jordi Guarinos
Percutaneous coronary intervention of chronic total occlusion is a particular interventional area which requires high level of operator's experience and the support of additional tools based on intracoronary image such as intravascular ultrasound in many cases to clarify difficulties during procedures and to increase success rate. Implantation of long stents in many cases, the presence of stump ambiguity, and the use of specific techniques in this kind of interventions, such as reverse controlled antegrade and retrograde subintimal tracking (CART) and reverse CART make necessary in many cases the use of intravascular ultrasound for a better understanding of the situation, for reducing eventual complications and increasing procedural success rate...
October 13, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29173601/autologous-bone-marrow-stem-cell-therapy-in-patients-with-st-elevation-myocardial-infarction-a-systematic-review-and-meta-analysis
#13
REVIEW
Maya M Jeyaraman, Rasheda Rabbani, Leslie Copstein, Wasan Sulaiman, Farnaz Farshidfar, Hessam H Kashani, Sheikh M Z Qadar, Qingdong Guan, Becky Skidmore, Elissavet Kardami, John Ducas, Samer Mansour, Ryan Zarychanski, Ahmed M Abou-Setta
BACKGROUND: Randomized controlled trials (RCTs) on bone marrow stem cell (BMSC) therapy in ST-elevation myocardial infarction (STEMI) patients have reported conflicting results. Our main objective was to critically appraise and meta-analyze best-available evidence on efficacy and safety of intracoronary administration of autologous BMSC therapy in STEMI patients after primary percutaneous coronary intervention. METHODS: We conducted a search of MEDLINE, PubMed, EMBASE, CENTRAL, Global Health, CINAHL, and conference proceedings in February 2017...
December 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/29171086/a-randomized-study-of-prourokinase-during-primary-percutaneous-coronary-intervention-in-acute-st-segment-elevation-myocardial-infarction
#14
Wei Geng, Qi Zhang, Jingmin Liu, Xiang Tian, Libo Zhen, Da Song, Ying Yang, Haiyun Meng, Yafang Wang, Jianjun Chen
OBJECTIVES: To evaluate the efficacy and safety of intracoronary administration of prourokinase via balloon catheter during primary percutaneous coronary interventions (PCI) in patients with acute ST-segment elevation myocardial infarction (STEMI). METHODS: Acute STEMI patients underwent primary PCI were randomly divided into two groups: intracoronary prourokinase (IP) group (n = 118) and control group (n = 112). During primary PCI, prourokinase or saline were injected to the distal end of the culprit lesion via balloon catheter after balloon catheter dilatation...
November 23, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29169759/abnormal-coronary-vasoreactivity-in-transient-left-ventricular-apical-ballooning-tako-tsubo-syndrome
#15
Edoardo Verna, Stefano Provasoli, Sergio Ghiringhelli, Fabrizio Morandi, Jorge Salerno-Uriarte
BACKGROUND: The exact etiology and pathophysiologic mechanisms of tako-tsubo syndrome (TTS) remain controversial. OBJECTIVE: To further evaluate the abnormal coronary vasoreactivity and its possible anatomical substrate in TTS. METHODS: We studied 47 patients (46 women; age 67±12years) who underwent diagnostic cardiac catheterization and evaluation of coronary vasoreactivity by sequential acetylcholine (Ach), nitroglycerine and adenosine testing with angiographic and intracoronary pressure-Doppler flow monitoring...
January 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29166637/assessing-vessel-tone-during-coronary-artery-spasm-by-dual-acquisition-multidetector-computed-tomography-angiography
#16
Cai De Jin, Moo Hyun Kim, Eun Ju Kang, Young Rak Cho, Tae Ho Park, Ki Nam Lee, Victor Serebruany
BACKGROUND: Diminished vascular tone is an established biomarker of heart damage. Little is known about the extent of coronary vessel tone (CVT) with spasm as assessed by dual-acquisition multidetector computed tomography angiography (MCTA) in patients with vasospastic angina (VSA). OBJECTIVE: We evaluated the CVT modulated by intravenous nitrate injection (INI) using MCTA imaging in VSA patients. METHODS: Twenty-one VSA patients (60 ± 9 years; 76% males) who underwent initial MCTA (without morning vasodilation), followed by an intracoronary ergonovine provocation test were included...
November 23, 2017: Cardiology
https://www.readbyqxmd.com/read/29154687/pyruvate-enhancement-of-cardiac-performance-cellular-mechanisms-and-clinical-application
#17
Robert T Mallet, Albert H Olivencia-Yurvati, Rolf Bünger
Cardiac contractile function is adenosine-5'-triphosphate (ATP)-intensive, and the myocardium's high demand for oxygen and energy substrates leaves it acutely vulnerable to interruptions in its blood supply. The myriad cardioprotective properties of the natural intermediary metabolite pyruvate make it a potentially powerful intervention against the complex injury cascade ignited by myocardial ischemia-reperfusion. A readily oxidized metabolic substrate, pyruvate augments myocardial free energy of ATP hydrolysis to a greater extent than the physiological fuels glucose, lactate and fatty acids, particularly when it is provided at supra-physiological plasma concentrations...
January 1, 2017: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/29153956/effect-of-laser-activated-bleaching-on-the-chemical-stability-and-morphology-of-intracoronal-dentin
#18
Fabiane Carneiro Lopes, Renato Roperto, Anna Akkus, Ozan Akkus, Regina Guenka Palma-Dibb, Manoel Damião de Sousa-Neto
OBJECTIVES: To evaluate the effect of the bleaching with 35% hydrogen peroxide either activated or not by a 970nm diode laser on the chemical stability and dentin surface morphology of intracoronary dentin. METHODS: Twenty-seven slabs of intracoronary dentin specimens (3×3mm) were distributed into three groups (n=9), according to surface treatment: HP - 35% hydrogen peroxide (1×4'), DL - 970nm diode laser (1×30"/0,8W/10Hz), HP+DL - 35% HP activated with 970nm diode laser (1×30"/0,8W/10Hz leaving the gel in contact to the surface for 4' after activation)...
November 13, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/29153502/clinical-outcomes-following-intravascular%C3%A2-imaging-guided-versus-coronary-angiography-guided-percutaneous-coronary-intervention-with%C3%A2-stent-implantation-a%C3%A2-systematic-review-and-bayesian-network-meta-analysis-of%C3%A2-31%C3%A2-studies-and-17-882-patients
#19
Sergio Buccheri, Gabriele Franchina, Sara Romano, Sebastiano Puglisi, Giuseppe Venuti, Paolo D'Arrigo, Bruno Francaviglia, Matteo Scalia, Antonio Condorelli, Marco Barbanti, Piera Capranzano, Corrado Tamburino, Davide Capodanno
OBJECTIVES: The authors sought to explore the comparative clinical efficacy of different imaging modalities for guiding percutaneous coronary interventions (PCI). BACKGROUND: Coronary angiography (CA) is the standard imaging modality for intraprocedural guidance of PCI. Intracoronary imaging techniques, including intravascular ultrasound (IVUS) and optical coherence tomography (OCT), can overcome some limitations of CA. METHODS: Comprehensive hierarchical Bayesian network meta-analysis of randomized clinical trials and adjusted observational studies comparing clinical outcomes of PCI with stent implantation guided by CA, IVUS, or OCT...
November 8, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29153497/is-the-intracoronary-electrocardiogram-lesion-specific
#20
Emre Aslanger, Mustafa Aytek Şimşek, Ayça Türer Cabbar, Olcay Özveren, Muzaffer Değertekin
No abstract text is available yet for this article.
November 7, 2017: JACC. Cardiovascular Interventions
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