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https://www.readbyqxmd.com/read/29342038/utility-of-noncontrast-magnetic-resonance-imaging-for-detection-of-recurrent-vestibular-schwannoma
#1
Jamie C Williams, Carrie M Carr, Laurence J Eckel, Amy L Kotsenas, Christopher H Hunt, Matthew L Carlson, John I Lane
BACKGROUND: Gadolinium-enhanced T1-weighted magnetic resonance imaging (MRI) (T1WI) is the conventional imaging technique of choice to detect vestibular schwannoma (VS) recurrence or regrowth, despite suboptimal specificity secondary to enhancing postoperative changes. Furthermore, recent concerns regarding the accumulation of gadolinium in body tissues have led for a call to reduce the number of contrast-enhanced examinations. The objective of the current study is to evaluate the diagnostic accuracy of high-resolution noncontrast (three-dimensional [3D] T2) MRI relative to gadolinium-enhanced T1WI in the detection of VS recurrence after resection...
January 16, 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29341022/in-vivo-pharmacokinetics-of-magnetic-nanoparticles
#2
Carlos Caro, M Carmen Muñoz-Hernández, Manuel Pernia Leal, María Luisa García-Martín
Over the past few years, many papers have been published on the nanomedical applications of magnetic nanoparticles. However, most studies lack important information about the in vivo behavior of these nanoparticles, which is a critical aspect for their rational design. In this chapter we describe a simple protocol for the in vivo characterization of the pharmacokinetics of magnetic nanoparticles intravenously injected in mice, using basic MRI sequences.
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29341017/molecular-magnetic-resonance-imaging-mmri
#3
Maxime Gauberti, Antoine P Fournier, Denis Vivien, Sara Martinez de Lizarrondo
Molecular magnetic resonance imaging (mMRI) enables the detection of a protein of interest in vivo, in a noninvasive manner. The general concept of mMRI is to target a contrast agent to a protein of interest, and to perform a contrast-sensitive MRI sequence. Typically, contrast agents are made of a "contrastophore" (the part of the construct responsible for the contrast on the images) and a targeting moiety ("pharmacophore"). Recently, the development of a new family of contrastophore carrying a high payload of iron oxide (micro-sized particles of iron oxide, MPIO) has led to a dramatic increase in the sensitivity of mMRI...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29341004/diffusion-weighted-magnetic-resonance-imaging
#4
Irene Guadilla, Daniel Calle, Pilar López-Larrubia
Magnetic resonance imaging (MRI) is a technique based on the contents and relaxation features of water in tissues. In basic MRI sequences, diffusion phenomenon of water molecules is not taken into account although it has a notable influence in the relaxation times, and therefore in the signal intensity of images. In fact, MRI techniques that take advantage of water diffusion have experienced a huge development in last years. Diffusion-weighted imaging (DWI) has spectacularly evolved reaching nowadays a great impact both in clinical and preclinical imaging-especially in the neuroimaging field-and in basic research...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29339222/measurement-variability-of-liver-metastases-from-neuroendocrine-tumors-on-different-magnetic-resonance-imaging-sequences
#5
T Lestra, L Kanagaratnam, S Mulé, A Janvier, H Brixi, G Cadiot, A Dohan, C Hoeffel
PURPOSE: To assess dimension measurement variability of liver metastases from neuroendocrine tumors (LMNET) on different magnetic resonance imaging (MRI) sequences. MATERIAL AND METHODS: In this institutional review board-approved retrospective study from January 2011 to December 2012, all liver MRI examinations performed at our department in patients with at least one measurable LMNET according to response evaluation criteria in solid tumors (RECIST1.1) were included...
January 12, 2018: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/29339139/improved-coronary-magnetic-resonance-angiography-using-gadobenate-dimeglumine-in-pediatric-congenital-heart-disease
#6
Miguel Silva Vieira, Markus Henningsson, Nathalie Dedieu, Vassilios S Vassiliou, Aaron Bell, Sujeev Mathur, Kuberan Pushparajah, Carlos Alberto Figueroa, Tarique Hussain, René Botnar, Gerald F Greil
BACKGROUND: CMRA in pediatrics remains challenging due to the smaller vessel size, high heart rates (HR), potential image degradation caused by limited patient cooperation and long acquisition times. High-relaxivity contrast agents have been shown to improve coronary imaging in adults, but limited data is available in children. We sought to investigate whether gadobenate dimeglumine (Gd-BOPTA) together with self-navigated inversion-prepared coronary magnetic resonance angiography (CMRA) sequence design improves coronary image quality in pediatric patients...
January 12, 2018: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/29337774/gadolinium-based-contrast-agent-during-pelvic-mri-contribution-to-patient-management-in-rectal-cancer
#7
Marina J Corines, Stephanie Nougaret, Martin R Weiser, Monika Khan, Marc J Gollub
BACKGROUND: Few publications exist regarding gadolinium-enhanced sequences in rectal MRI. None have evaluated its potential impact on patient management. OBJECTIVE: This study aimed to assess whether gadolinium-enhanced sequences, including dynamic contrast enhancement, change radiologic interpretation and clinical management of rectal cancer. DESIGN: This is a retrospective analysis of 100 rectal MRIs (50 baseline and 50 postneoadjuvant treatment), both without and with gadolinium-enhanced sequences...
February 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29334405/high-resolution-dental-mri-for-planning-palatal-graft-surgery-a-clinical-pilot-study
#8
Tim Hilgenfeld, Thorsten Kästel, Alexander Heil, Peter Rammelsberg, Sabine Heiland, Martin Bendszus, Franz Sebastian Schwindling
AIM: To evaluate whether high-resolution, non-contrast-enhanced dental MRI can be used for accurate determination of palatal-masticatory-mucosa-thickness (PMMT) and to locate the greater palatal artery (GPA). MATERIALS AND METHODS: In five volunteers (4 males, 1 female; mean age 30.2±0.4 years) two independent raters measured PMMT by use of dental MRI in 180 positions. For comparison, clinical bone sounding was performed. The GPA was identified in time-of-flight (TOF) angiography and MSVAT-SPACE-prototype sequence...
January 15, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29334236/wb-mri-and-oncology-recent-major-advances
#9
Vassiliki Pasoglou, Nicolas Michoux, Ahmed Larbi, Van Nieuwenhove Sandy, Frédéric Lecouvet
Magnetic Resonance Imaging (MRI) is a very attractive approach for tumor detection and oncological staging with its absence of ionizing radiation, high soft tissue contrast and spatial resolution. Less than ten years ago the use of Whole Body MRI (WB-MRI) protocols was uncommon due to many limitations, such as the long acquisition times and limited availability. This decade has marked substantial progress in WB-MRI protocols. This very promising technique is rapidly arising from the research world and is becoming a commonly used exam for tumor detection, due to recent technological developments and validation of WB-MRI by multiple studies and consensus papers...
January 15, 2018: British Journal of Radiology
https://www.readbyqxmd.com/read/29334139/interleaved-susceptibility-weighted-and-flair-mri-for-imaging-lesion-penetrating-veins-in-multiple-sclerosis
#10
Refaat E Gabr, Amol S Pednekar, Arash Kamali, John A Lincoln, Flavia M Nelson, Jerry S Wolinsky, Ponnada A Narayana
PURPOSE: To simultaneously image brain lesions and veins in multiple sclerosis. METHODS: An interleaved sequence was developed to simultaneously acquire 3-dimensional T2*-weighted (or susceptibility-weighted (SW)) and fluid-attenuated inversion recovery (FLAIR) images on a 3T MRI system. The pulse sequence parameters were calculated to minimize signal perturbation from steady state while maintaining acceptable image contrast and scan time. Fifteen multiple sclerosis patients were enrolled in this prospective study and underwent a standard multiple sclerosis imaging protocol...
January 15, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29332200/simultaneous-multi-slice-accelerated-turbo-spin-echo-of-the-knee-in-pediatric-patients
#11
Sebastien Benali, Patrick R Johnston, Ali Gholipour, Monet E Dugan, Keith Heberlein, Himanshu Bhat, Sarah D Bixby
PURPOSE: To compare knee MRI performed with the integrated parallel acquisition technique (PAT) and simultaneous multislice (SMS) turbo spin echo (TSE) T2-weighted (T2w) sequences with conventional TSE sequences in pediatric patients. MATERIALS AND METHODS: This was a retrospective IRB-approved study. Seventy-four subjects (26 male, 48 female, mean age 15.3 years, range 8-20) underwent 3-T MRI of the knee with a T2w TSE pulse sequence prototype with four-fold PAT and SMS acceleration as well as the standard PAT-only accelerated sequences...
January 13, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/29331056/exploring-the-advantages-of-multiband-fmri-with-simultaneous-eeg-to-investigate-coupling-between-gamma-frequency-neural-activity-and-the-bold-response-in-humans
#12
Makoto Uji, Ross Wilson, Susan T Francis, Karen J Mullinger, Stephen D Mayhew
We established an optimal combination of EEG recording during sparse multiband (MB) fMRI that preserves high-resolution, whole-brain fMRI coverage while enabling broad-band EEG recordings which are uncorrupted by MRI gradient artefacts (GAs). We first determined the safety of simultaneous EEG recording during MB fMRI. Application of MB factor = 4 produced <1°C peak heating of electrode/hardware during 20 min of GE-EPI data acquisition. However, higher SAR sequences require specific safety testing, with greater heating observed using PCASL with MB factor = 4...
January 13, 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29330713/low-field-magnetic-resonance-imaging-offers-potential-for-measuring-tibial-component-migration
#13
F F Schröder, N J J Verdonschot, B Ten Haken, A Peters, A J H Vochteloo, D F M Pakvis, R Huis In't Veld
BACKGROUND: Roentgen stereophotogrammetric analysis (RSA) is used to measure early prosthetic migration and to predict future implant failure. RSA has several disadvantages, such as the need for perioperatively inserted tantalum markers. Therefore, this study evaluates low-field MRI as an alternative to RSA. The use of traditional MRI with prostheses induces disturbing metal artifacts which are reduced by low-field MRI. The purpose of this study is to assess the feasibility to use low-field (0...
January 12, 2018: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/29330616/-magnetic-resonance-cisternography
#14
REVIEW
U Yilmaz
CLINICAL/METHODICAL ISSUE: Conventional MRI can be insufficient to depict certain pathologies of the cerebrospinal fluid (CSF)-filled spaces. STANDARD RADIOLOGICAL METHODS: 3-D T2-weighted sequences and phase-contrast imaging have a high sensitivity for pathologies of the CSF-filled spaces, but are susceptible to artifacts in some cases. METHODICAL INNOVATIONS/PERFORMANCE: Magnetic resonance (MR) cisternography directly depicts the connection between CSF-filled spaces...
January 12, 2018: Der Radiologe
https://www.readbyqxmd.com/read/29328531/thalamic-atrophy-in-ms-an-mri-marker-of-neurodegeneration-throughout-disease
#15
Christina J Azevedo, Steven Y Cen, Sankalpa Khadka, Shuang Liu, John Kornak, Yonggang Shi, Ling Zheng, Stephen L Hauser, Daniel Pelletier
OBJECTIVE: Thalamic volume is a candidate MRI-based marker associated with neurodegeneration to hasten development of neuroprotective treatments. Our objective is to describe the longitudinal evolution of thalamic atrophy in MS and normal aging, and to estimate sample sizes for study design. METHODS: 601 subjects (2632 MRI scans) were analyzed. 520 subjects with relapse-onset MS [CIS(90); RR(392); SP(38)] underwent annual standardized 3T MRI scans for an average of 4...
January 12, 2018: Annals of Neurology
https://www.readbyqxmd.com/read/29327374/dynamic-coronary-mr-angiography-in-a-pig-model-with-hyperpolarized-water
#16
Kasper Wigh Lipsø, Esben Søvsø Szocska Hansen, Rasmus Stilling Tougaard, Christoffer Laustsen, Jan Henrik Ardenkjaer-Larsen
PURPOSE: To investigate dynamic coronary MR angiography using hyperpolarized water as a positive contrast agent. Hyperpolarization can increase the signal by several orders of magnitude, and has recently been translated to human cardiac application. The aim was to achieve large 1 H signal enhancement to allow high-resolution imaging of the coronary arteries. METHODS: Protons in D2 O were hyperpolarized by dissolution dynamic nuclear polarization. A total of 18 mL of hyperpolarized water was injected into the coronary arteries of healthy pigs (N = 9; 3 injections in 3 animals)...
January 12, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29326046/multi-tissue-partial-volume-quantification-in-multi-contrast-mri-using-an-optimised-spectral-unmixing-approach
#17
Guylaine Collewet, Saïd Moussaoui, Cécile Deligny, Tiphaine Lucas, Jérôme Idier
Multi-tissue partial volume estimation in MRI images is investigated with a viewpoint related to spectral unmixing as used in hyperspectral imaging. The main contribution of this paper is twofold. It firstly proposes a theoretical analysis of the statistical optimality conditions of the proportion estimation problem, which in the context of multi-contrast MRI data acquisition allows to appropriately set the imaging sequence parameters. Secondly, an efficient proportion quantification algorithm based on the minimisation of a penalised least-square criterion incorporating a regularity constraint on the spatial distribution of the proportions is proposed...
January 8, 2018: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/29324862/taking-two-to-tango-fmri-analysis-of-improvised-joint-action-with-physical-contact
#18
Léa A S Chauvigné, Michel Belyk, Steven Brown
Many forms of joint action involve physical coupling between the participants, such as when moving a sofa together or dancing a tango. We report the results of a novel two-person functional MRI study in which trained couple dancers engaged in bimanual contact with an experimenter standing next to the bore of the magnet, and in which the two alternated between being the leader and the follower of joint improvised movements. Leading showed a general pattern of self-orientation, being associated with brain areas involved in motor planning, navigation, sequencing, action monitoring, and error correction...
2018: PloS One
https://www.readbyqxmd.com/read/29324754/fast-quantitative-murine-cardiac-19f-mri-mrs-of-pfce-labeled-progenitor-stem-cells-and-macrophages-at-9-4t
#19
Christakis Constantinides, Mahon Maguire, Eileen McNeill, Ricardo Carnicer, Edyta Swider, Mangala Srinivas, Carolyn A Carr, Jurgen E Schneider
PURPOSE: To a) achieve cardiac 19F-Magnetic Resonance Imaging (MRI) of perfluoro-crown-ether (PFCE) labeled cardiac progenitor stem cells (CPCs) and bone-derived bone marrow macrophages, b) determine label concentration and cellular load limits, and c) achieve spectroscopic and image-based quantification. METHODS: Theoretical simulations and experimental comparisons of spoiled-gradient echo (SPGR), rapid acquisition with relaxation enhancement (RARE), and steady state at free precession (SSFP) pulse sequences, and phantom validations, were conducted using 19F MRI/Magnetic Resonance Spectroscopy (MRS) at 9...
2018: PloS One
https://www.readbyqxmd.com/read/29324329/cystic-mediastinal-masses-and-the-role-of-mri
#20
REVIEW
Rachna Madan, Lisa Ratanaprasatporn, Linda Ratanaprasatporn, Brett W Carter, Jeanne B Ackman
While some cystic masses can be definitively diagnosed on CT, others remain indeterminate. Because of its intrinsic superior soft tissue resolution, MR is an important tool in the evaluation of select mediastinal masses that are incompletely characterized on CT. This review describes how non-vascular MR provides greater diagnostic precision in the evaluation of indeterminate cystic mediastinal masses on CT. It also emphasizes key MR pulse sequences for optimal evaluation of problematic mediastinal masses.
December 27, 2017: Clinical Imaging
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