keyword
MENU ▼
Read by QxMD icon Read
search

Drug eluting beads

keyword
https://www.readbyqxmd.com/read/29739489/safety-and-efficacy-analysis-of-deb-tace-treatment-in-elderly-patients-with-hepatocellular-carcinoma-a-comparative-cohort-study
#1
Qing Yang, Xiaosheng Jin, Fangpeng Ye, Bingru Zheng, Xiangpang Xie, Ya Luo, Zhenjing Shi, Changsheng Shi
The aim of this study was to explore the difference of liver function change, safety profiles and efficacy of drug-eluting bead transarterial chemoembolization (DEBTACE) therapy between elderly and middle-aged hepatocellular carcinoma (HCC) patients. 91 HCC patients were enrolled in this prospective cohort study. They were treated by DEB-TACE therapy and divided into elderly group (age >= 65 years, n=30) and middle-aged group (age < 65 years, n=61), liver function, safety profiles and treatment response were recorded...
May 8, 2018: Oncology Research
https://www.readbyqxmd.com/read/29739274/comprehensive-analysis-of-factors-affecting-clinical-response-and-short-term-survival-to-drug-eluting-bead-transarterial-chemoembolization-for-treatment-in-patients-with-liver-cancer
#2
Xia Wu, Ran Chen, Weiliang Zheng, Hongjie Hu
This study aimed to investigate the clinical response and short-term survival and further explore the comprehensive factors for predicting clinical outcomes in patients with liver cancer treated by drug-eluting beads transarterial chemoembolization . Forty-nine patients with liver cancer who received drug-eluting beads transarterial chemoembolization treatment were consecutively enrolled in this cohort study. Demographic features, medical histories, clinicopathological properties, biochemical indexes, previous treatments, and chemoembolization reagents were recorded...
January 1, 2018: Technology in Cancer Research & Treatment
https://www.readbyqxmd.com/read/29661601/corrigendum-to-evaluation-of-texture-analysis-parameter-for-response-prediction-in-patients-with-hepatocellular-carcinoma-undergoing-drug-eluting-bead-transarterial-chemoembolization-deb-tace-using-biphasic-contrast-enhanced-ct-image-data-correlation-with-liver
#3
Christopher Kloth, Wolfgang Maximilian Thaiss, Rainer Kärgel, Rainer Grimmer, Jan Fritz, Sorin Dumitru Ioanoviciu, Dominik Ketelsen, Konstantin Nikolaou, Marius Horger
No abstract text is available yet for this article.
April 13, 2018: Academic Radiology
https://www.readbyqxmd.com/read/29609903/transarterial-chemoembolization-tace-in-the-management-of-hepatocellular-carcinoma-results-of-a-french-national-survey-on-current-practices
#4
A Fohlen, J P Tasu, H Kobeiter, J M Bartoli, J P Pelage, B Guiu
PURPOSE: To report current practices of transarterial chemoembolization (TACE) by interventional radiologists (IR) for hepatocellular carcinoma (HCC) through a French national survey. MATERIALS AND METHODS: An electronic survey was sent by e-mail to 232 IRs performing TACE in 32 private or public centers. The survey included 66 items including indications for TACE, technical aspects of TACE, other locally available treatments for HCC, follow-up imaging and general aspects of interventional radiology practices...
March 30, 2018: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/29587773/callispheres-drug-eluting-beads-versus-lipiodol-transarterial-chemoembolization-in-the-treatment-of-hepatocellular-carcinoma-a-short-term-efficacy-and-safety-study
#5
Baolin Wu, Jun Zhou, Gonghao Ling, Dongyong Zhu, Qingyun Long
BACKGROUND: The present study aimed to evaluate the short-term efficacy and safety of drug-eluting beads transarterial chemoembolization (DEB-TACE) with CalliSpheres Beads loaded with doxorubicin (DOX) in the treatment of Chinese patients with hepatocellular carcinoma (HCC) compared to conventional TACE (cTACE). METHODS: A total of 54 patients with HCC treated by TACE from June 2016 to February 2017 were retrospectively analyzed. These included 24 cases in the DEB-TACE group and 30 cases in the cTACE group...
March 27, 2018: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29555570/reproducibility-of-mrecist-in-measurement-and-response-assessment-for-hepatocellular-carcinoma-treated-by-transarterial-chemoembolization
#6
Moon Hyung Choi, Ga Eun Park, Soon Nam Oh, Michael Yong Park, Sung Eun Rha, Young Joon Lee, Seung Eun Jung, Joon-Il Choi
RATIONALE AND OBJECTIVES: To evaluate the reproducibility of Modified Response Evaluation Criteria in Solid Tumors (mRECIST) for hepatocellular carcinoma (HCC) after transarterial chemoembolization (TACE) using multiphasic computed tomography. MATERIALS AND METHODS: The institutional review board approved this retrospective study. We evaluated 97 patients who underwent TACE (60 conventional TACE [cTACE] and 37 drug-eluting bead TACE [DEB-TACE]) for HCC from 2010 to 2014...
March 16, 2018: Academic Radiology
https://www.readbyqxmd.com/read/29520201/computed-tomographic-perfusion-imaging-for-the-prediction-of-response-and-survival-to-transarterial-chemoembolization-of-hepatocellular-carcinoma
#7
Peter Popovic, Ana Leban, Klara Kregar, Manca Garbajs, Rok Dezman, Matjaz Bunc
Background: The purpose of this retrospective cohort study was to evaluate the clinical value of computed tomographic perfusion imaging (CTPI) parameters in predicting the response to treatment and overall survival in patients with hepatocellular carcinoma (HCC) treated with drug-eluting beads transarterial chemoembolization (DEBTACE). Patients and methods: Between December 2010 and January 2013 eighteen patients (17 men, 1 woman; mean age 69 ± 5.8 years) with intermediate stage HCC underwent CTPI of the liver prior to treatment with DEBTACE...
March 2018: Radiology and Oncology
https://www.readbyqxmd.com/read/29484132/cryoablation-with-drug-loaded-bead-embolization-in-the-treatment-of-unresectable-hepatocellular-carcinoma-safety-and-efficacy-analysis
#8
Jian-Ying Zeng, Xiang-Hao Piao, Zhong-Yuan Zou, Qing-Feng Yang, Zi-Lin Qin, Ji-Bing Chen, Liang Zhou, Li-Zhi Niu, Jian-Guo Liu
This study aimed to explore the efficacy and safety of drug-eluting bead (DEB) embolization (DEB-TACE) when combined with cryoablation in the treatment of unresectable hepatocellular carcinoma (HCC). The study was a single-center randomized controlled trial comprised of 60 patients with HCC conducted between August 2015 and October 2017. The patients were randomly divided into two groups: DEB-TACE combined with cryoablation (DEB-TACE-Cryo group) or cryoablation alone (Cryo group). Inter-group differences in overall survival, progression-free survival, and adverse reactions were assessed...
January 26, 2018: Oncotarget
https://www.readbyqxmd.com/read/29434732/sustained-multiple-organ-ischaemia-after-transarterial-chemoembolization-with-drug-eluting-beads-for-hepatocellular-carcinoma
#9
Young Woon Kim, Jung Hyun Kwon, Soon Woo Nam, Jeong Won Jang, Hyun Suk Jung, Yu Ri Shin, Eun Su Park, Dong Jae Shim
Transarterial chemoembolization (TACE) with drug-eluting beads (DC beads) may enhance drug delivery to tumours and reduce systemic toxicity. TACE with DC beads leads to significantly fewer serious side-effects compared with conventional TACE. A 66-year-old man with hepatocellular carcinoma (HCC) complained of continuous abdominal pain 1 month after TACE with DC beads. At the time of TACE, angiography revealed severe stenosis of both hepatic arteries. The diagnostic work up on admission suggested severe bile duct injury with regional bile duct dilatation, segmental liver and spleen infarction, necrotizing pancreatitis, as well as gastric and duodenal ulcers...
February 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29399283/efficacy-of-intra-arterial-contrast-enhanced-ultrasonography-during-transarterial-chemoembolization-with-drug-eluting-beads-for-hepatocellular-carcinoma
#10
Kazue Shiozawa, Manabu Watanabe, Takashi Ikehara, Shuhei Yamamoto, Takashi Matsui, Yoshinori Saigusa, Yoshinori Igarashi, Iruru Maetani
AIM: To assess the usefulness of intra-arterial contrast-enhanced ultrasonography (IAUS) during transarterial chemoembolization (TACE) with drug-eluting beads (DEB) for hepatocellular carcinoma (HCC). METHODS: Thirty two patients with 39 HCC underwent DEB-TACE guided with IAUS, and examined by contrast-enhanced ultrasonography (CEUS) or dynamic CT after DEB-TACE were enrolled in this study. CEUS findings before DEB-TACE and IAUS findings were compared. Treatments judged to be complete and incomplete for lesions were appropriate and insufficient, respectively...
January 27, 2018: World Journal of Hepatology
https://www.readbyqxmd.com/read/29381102/transvascular-therapy-of-hepatocellular-carcinoma-hcc-status-and-developments
#11
Daniel Gnutzmann, Nikolas Kortes, Migle Sumkauskaite, Anne Schmitz, Karl-Heinz Weiss, Boris Radeleff
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Only 30-40% of patients diagnosed with HCC are candidates for curative treatment options. The remaining majority of patients undergo local, regional or systemic palliative therapies. Transvascular therapy of HCC takes advantage of the fact that hypervascularized HCCs receive their main perfusion from the hepatic artery. In this context transvascular therapy describes different therapies: bland embolization (transarterial embolization, TAE), cTACE (conventional transarterial chemoembolization), DEB-TACE (TACE with drug-eluting beads, DEB) and SIRT (selective internal radiation therapy, radioembolization)...
April 2018: Minimally Invasive Therapy & Allied Technologies: MITAT
https://www.readbyqxmd.com/read/29375202/drug-eluting-beads-transarterial-chemoembolization-for-hepatocellular-carcinoma-current-state-of-the-art
#12
REVIEW
Antonio Facciorusso
Transarterial chemoembolization (TACE) represents the current gold standard for hepatocellular carcinoma (HCC) patients in intermediate stage. Conventional TACE (cTACE) is performed with the injection of an emulsion of a chemotherapeutic drug with lipiodol into the artery feeding the tumoral nodules, followed by embolization of the same vessel to obtain a synergistic effect of drug cytotoxic activity and ischemia. Aim of this review is to summarize the main characteristics of drug-eluting beads (DEB)-TACE and the clinical results reported so far in the literature...
January 14, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29374736/efficacy-and-safety-of-drug-eluting-bead-tace-with-microspheres-150-%C3%AE-m-for-the-treatment-of-hepatocellular-carcinoma
#13
Tim Sattler, Christina Bredt, Stefanie Surwald, Christian Rust, Johannes Rieger, Tobias Jakobs
BACKGROUND/AIM: To retrospectively evaluate the efficacy and safety of drug eluting bead (DEB) transarterial chemoembolisation (TACE) with microspheres <150 μm for the treatment of hepatocellular carcinoma (HCC) with respect to overall survival, progression-free survival, tumor response and the peri-interventional toxicity. MATERIALS AND METHODS: In this retrospective, single-center study we analyzed 32 HCC-patients (BCLC A: 10 patients, BCLC B: 17 patients, BCLC C: 5 patients), who were treated with (DEB) <15 μm (DCBeadM1®) loaded with epirubicin between 2011 and 2015...
February 2018: Anticancer Research
https://www.readbyqxmd.com/read/29305365/rash-and-subcutaneous-fat-necrosis-after-deb-tace-with-doxorubicin
#14
Ahmed Gamal Elsayed, James M Martin, Toni Pacioles
A 73-year-old woman with hepatocellular carcinoma localised to the liver was treated with doxorubicin-loaded drug-eluting beads through transcatheter arterial chemoembolisation (DEB-TACE). She developed subcutaneous, erythematous, tender nodules in her abdomen 3 days after the procedure. PET/CT scan that was done to evaluate for evidence of disease progression showed mild avidity of these nodules. Biopsy showed fatty necrosis. Nodules started to improve spontaneously 2 weeks after onset. At 8 weeks after onset, lesions stabilised in size and the associated tenderness and erythema resolved...
January 5, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29193977/comment-on-in-vivo-drug-delivery-performance-of-lipiodol-based-emulsion-or-drug-eluting-beads-in-patients-with-hepatocellular-carcinoma
#15
Walter González, Jean-Marc Idée, Sebastien Ballet
No abstract text is available yet for this article.
January 2, 2018: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/29185767/reply-to-comment-on-in-vivo-drug-delivery-performance-of-lipiodol-based-emulsion-or-drug-eluting-beads-in-patients-with-hepatocellular-carcinoma
#16
Ilse R Dubbelboer, Elsa Lilienberg, Amar Karalli, Rimma Axelsson, Torkel B Brismar, Charlotte Ebeling Barbier, Agneta Norén, Frans Duraj, Mikael Hedeland, Ulf Bondesson, Erik Sjögren, Per Stål, Rickard Nyman, Hans Lennernäs
No abstract text is available yet for this article.
January 2, 2018: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/29180934/long-term-survival-in-a-patient-with-unresectable-liver-metastases-from-uveal-melanoma-treated-with-transarterial-chemoembolization-with-irinotecan-eluting-beads-case-report-and-review-of-literature
#17
Katarzyna Stanisławska, Honorata Stadnik, Mikołaj Nawrocki, Katarzyna Ramlau-Piątek, Robert Juszkat, Michał Drews
Introduction: Treatment of unresectable liver metastases (LM) from uveal melanoma (UM) remains a major clinical challenge. Systemic chemotherapy and chemoimmunotherapy regimens extrapolated from cutaneous melanoma are considered to be ineffective in therapy of metastases from uveal melanoma. Studies suggest that the progression of hepatic metastases rather than the primary tumor or metastases in other organs determines survival. Case report: We report a case of transarterial chemoembolization of 57-year-old man diagnosed with unresectable liver metastases from uveal melanoma with irinotecan eluting beads...
2017: Contemporary Oncology Współczesna Onkologia
https://www.readbyqxmd.com/read/29120489/in-vitro-chemosensitivity-of-feline-injection-site-associated-sarcoma-cell-lines-to-carboplatin
#18
Elizabeth A Maxwell, Heidi Phillips, David J Schaeffer, Timothy M Fan
OBJECTIVE: To determine the in vitro chemosensitivity of feline injection site-associated sarcoma (FISAS) cells to carboplatin concentrations generated by elution of carboplatin-impregnated calcium sulfate hemihydrate (CI-CSH) beads. STUDY DESIGN: In vitro study. SAMPLE: Five immortalized cell lines from histologically confirmed, primary FISASs. METHODS: For each cell line, one 96-well microplate was used for each time point (24, 48, 72 hours)...
February 2018: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/29113030/recent-advances-in-transarterial-embolotherapies-in-the-treatment-of-hepatocellular-carcinoma
#19
REVIEW
Edward Wolfgang Lee, Sarah Khan
Management of hepatocellular carcinoma (HCC) can be maximized with the utilization of multiple treatment modalities including transplant, surgical resection and locoregional therapies including ablative therapies and transarterial embolotherapies. Although transplant and surgical resection offer the best clinical outcomes, a limited number of patients are amenable to these surgical treatment options due to the advanced disease at presentation. Transarterial embolotherapies including conventional transarterial chemoembolization (cTACE), bland transarterial embolization (TAE), drug-eluting beads transarterial chemoembolization (DEB-TACE) and selective internal radiation therapy (SIRT) with Yttrium 90 (90Y) have played an increasingly important role for these patients with unresectable HCC...
December 2017: Clinical and Molecular Hepatology
https://www.readbyqxmd.com/read/29101054/mapping-of-drug-distribution-in-the-rabbit-liver-tumor-model-by-complementary-fluorescence-and-mass-spectrometry-imaging
#20
Katrin Fuchs, Andras Kiss, Pierre E Bize, Rafael Duran, Alban Denys, Gérard Hopfgartner, Gerrit Borchard, Olivier Jordan
This study describes the use of fluorescence imaging and mass spectrometry imaging, for imaging the anti-angiogenic drug sunitinib, used to treat liver cancer. These techniques allowed for the assessment of local delivery of the unlabeled therapeutic drug. More specifically, the spatial distribution of the drug and its metabolites after local administration was investigated, and drug levels in tumor and liver tissue over time were quantified. For this purpose, sunitinib-eluting microspheres were locoregionally injected into the tumor feeding arteries of rabbits bearing liver tumors...
January 10, 2018: Journal of Controlled Release: Official Journal of the Controlled Release Society
keyword
keyword
8544
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"