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https://www.readbyqxmd.com/read/27617610/unusual-manifestation-of-mucosal-plasmacytosis-mimicking-erythema-multiforme
#1
Keshavamurthy Vinay, Chougule Abhijit, Sunil Dogra
Mucosal plasmacytoses constitute a group of idiopathic inflammatory disorders, characterized by a dense infiltrate of plasma cells at the mucocutaneous junction without any recognizable dermatosis or neoplasm. We report an unusual clinical presentation of mucosal plasmacytosis presenting with hemorrhagic crusting of the lips, mimicking erythema multiforme.
2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/26508289/macular-pigmentation-complicating-irritant-contact-dermatitis-and-viral-warts-in-laugier-hunziker-syndrome
#2
B Bhoyrul, J Paulus
Laugier-Hunziker syndrome (LHS) is a rare acquired disorder characterized by macu-lar pigmentation of the lips and oral mucosa, with frequent longitudinal melanonychia. Involvement of other areas, such as the genitalia and fingers, has rarely been described. LHS is a benign condition with no known systemic manifestations. We report the case of a woman who developed melanotic macules on her fingers and elbow 16 years after the onset of pigmentation of her lips. This unusual feature of LHS in our patient was associated with irritant contact dermatitis and viral warts...
April 2016: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/26415314/perioral-dermatitis-still-a-therapeutic-challenge
#3
REVIEW
Zrinka Bukvić Mokos, Ana Kummer, Elvira Lazić Mosler, Romana Čeović, Aleksandra Basta-Juzbašić
Perioral dermatitis is a common and often chronic dermatosis. In its classic form, it primarily affects women aged 15 to 45 years, but there are also variants including lupus-like and granulomatous perioral dermatitis, where granulomatous form is more common in childhood and affects mostly prepubescent boys. The etiopathogenesis of the disease remains unclear, but there is a frequent finding of prolonged use of topical products, especially corticosteroids, in the treatment of rosacea and seborrheic dermatitis, preceding the clinical manifestation of perioral dermatitis...
June 2015: Acta Clinica Croatica
https://www.readbyqxmd.com/read/25618204/-fixed-drug-eruption-after-taking-ethambutol
#4
A S Bakayoko, M Kaloga, M Kamagate, Z Kone, A T J Daix, E Ohui, I Gbery, K Domoua
INTRODUCTION: Fixed drug eruption (FDE) is a specific skin reaction and the only exclusively medicinal dermatosis. Among the drugs usually responsible are the antituberculous antibiotics including rifampicin and, less often, isoniazid and pyrazinamide. FDE after taking ethambutol is rarely described. CASE REPORT: A 32-year old HIV negative patient presented a FDE localized to the internal surface of the lips and the interdigital folds during the 4th month of antituberculous treatment comprising rifampicin, isoniazid and ethambutol...
January 2015: Revue des Maladies Respiratoires
https://www.readbyqxmd.com/read/25262747/dermatology-of-the-lips-inflammatory-diseases
#5
Irène Hitz Lindenmüller, Peter H Itin, Susanna K Fistarol
The sensitive transitional skin of the lips is a favored site for primary skin diseases, especially eczematous dermatitis. An inflammatory condition of the lips, eg chapped lips (cheilitis sicca) in atopic eczema, may be the only manifestation of a skin disease or appear as part of a generalized dermatosis. Inflammatory changes to the lips also occur in the context of systemic disorders such as lupus erythematosus or in allergic diseases. This article presents the most frequent and the most important forms of inflammatory cheilitis...
November 2014: Quintessence International
https://www.readbyqxmd.com/read/23346925/a-case-of-antibacterial-responsive-mucocutaneous-disease-in-a-seven-year-old-dwarf-lop-rabbit-oryctolagus-cuniculus-resembling-mucocutaneous-pyoderma-of-dogs
#6
L Benato, M R Stoeckli, S H Smith, S Dickson, K L Thoday, A Meredith
A seven-year-old, ovariohysterectomised female dwarf lop rabbit (Oryctolagus cuniculus) was referred with severe swelling and erythema of the mucocutaneous junctions of the lips, nares and vulva. Bilateral, severe periocular dermatitis was also present. Heavy pure growths of a member of the Staphylococcus intermedius group were cultured from nasal and aural swabs and skin biopsies. Other possible differential diagnoses were eliminated by standard tests. The clinical features and histopathological characteristics of the biopsies were most consistent with mucocutaneous pyoderma, a dermatosis previously reported in dogs but not in rabbits...
April 2013: Journal of Small Animal Practice
https://www.readbyqxmd.com/read/22548627/anti-neutrophil-cytoplasmic-antibody-positive-neutrophilic-dermatosis-of-the-dorsal-hands
#7
M Malik, W Perkins, I Leach
Neutrophilic dermatosis of the hands is a localized variant of Sweet syndrome (SS). It was first reported in 1995, and is an uncommon condition, with < 100 cases reported to date. The female preponderance, morphological and histological features, and response to treatment are similar to SS, but it differs in its distribution on the body. There may also be a lack of systemic features and inconsistent laboratory findings. Significantly, about half of all cases are associated with haematological problems, i...
December 2012: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/22345770/a-study-of-pathogenesis-of-acanthosis-nigricans-and-its-clinical-implications
#8
Neerja Puri
BACKGROUND: Acanthosis nigricans (AN) is a dermatosis characterized by thickened, hyperpigmented plaques, typically on the intertriginous surfaces and neck. Common in some populations, its prevalence depends on race. Clinicians should recognize AN; it heralds disorders ranging from endocrinologic disturbances to malignancy. In this review, we discuss the pathogenesis of AN and its clinical implications and management. MATERIALS AND METHODS: We selected 30 patients for the study...
November 2011: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/22095181/a-case-of-bullous-pemphigoid-in-infancy-treated-with-local-corticosteroids
#9
L Atzori, M Pau, R Podda, C Manieli, N Aste
Bullous pemphigoid (BP) is an immune-mediated subepidermal vesiculobullous eruption, whose true incidence is unknown, but it is considered extremely rare in children, with a usually indolent course and rare relapses. Diagnosis is often belated, because of the invasive assessment with biopsy for typical immune-pathologic findings to differentiate it from Dermatitis Herpetiformis and Linear IgA bullous dermatosis (LABD), more common in children. A 4-year-old girl presented with one year history of erythematous-edematous and erythematous-bullous eruptions on the genitalia, periocular regions, dorsal and palmo-plantar surfaces...
December 2011: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/22014984/iatrogenic-skin-injury-in-hospitalized-patients
#10
REVIEW
Carol E Cheng, Daniela Kroshinsky
Iatrogenic skin injuries in hospitalized patients range from drug-related complications to those related to procedures. Common drug complications include drug reaction with eosinophilia and systemic symptoms (DRESS), linear immunoglobulin (Ig) A bullous dermatosis, Stevens-Johnson syndrome/toxic epidermal necrolysis, and acute generalized exanthematous pustulosis. Contact dermatitis can result from surgical preparations of chlorhexidine and povidone-iodine, medical adhesives, topical postsurgical ointments, most commonly neomycin and bacitracin, and internal prostheses, including coronary stents, pacemakers, and metal joints...
November 2011: Clinics in Dermatology
https://www.readbyqxmd.com/read/21631981/duodeno-biliary-obstruction-in-peutz-jeghers-syndrome
#11
Eduardo Pérez-Torres, Margarita Fosado-Gayosso, Nashiely Gil-Rojas, María de Fátima Higuera-de la Tijera
BACKGROUND: Peutz-Jeghers syndrome (PJS) is a pathology with autosomal dominant inheritance characterized by the presence of hamartomatous polyposis and mucocutaneous pigmentation. We present a case report from the Hospital General of Mexico. CLINICAL CASE: We present the case of a 28-year-old male. During physical examination we noted hyperpigmented dermatosis of the oral mucosa and lips. The same condition was seen in both palms. The condition evolved with intolerance to oral feeding and progressive obstructive jaundice...
March 2011: Cirugia y Cirujanos
https://www.readbyqxmd.com/read/21526742/steroid-sparing-effect-of-mycophenolate-mofetil-in-the-treatment-of-a-subepidermal-blistering-autoimmune-disease-in-a-dog
#12
P J Ginel, B Blanco, R Lucena, C R Jiménez, C Peinado-Guitart, E Mozos
A 7-year-old female Cocker spaniel-cross was referred with an 8-month history of mucocutaneous erosive dermatitis. On physical examination, skin lesions affected the eyelids and periocular area, lips and vulva. Lesions were symmetrical with small diffuse superficial ulcers, haemorrhagic crusts, adherent purulent exudation in haired skin, and alopecia with hyperpigmentation and scarring. Histopathologic evaluation showed multiple, non-intact dermoepidermal junction vesicles and ulceration associated with a dermal lichenoid infiltrate...
December 2010: Journal of the South African Veterinary Association
https://www.readbyqxmd.com/read/21523519/-treatment-of-granulomatous-cheilitis-with-fumaric-acid-esters-in-a-young-woman
#13
R Kleine, L Bröhl, U Amon
Granulomatous cheilitis is a rare granulomatous inflammation of the lips of unknown origin; mainly young adults are affected. So far, there is no generally effectual treatment available for this disfiguring dermatosis. We show the efficacy of a treatment with fumaric acid esters reporting the case of a 14-year-old girl with granulomatous cheilitis resistant to previous therapy. Our successful therapy consisted of fumaric acid esters according to the therapeutic schedule for psoriasis and showed a good tolerance subjectively and objectively...
December 2011: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/20973736/laser-phototherapy-for-stevens-johnson-syndrome-a-case-report
#14
Alyne Simões, Patrícia Moreira de Freitas, Marina Stella Bello-Silva, Jan Tunér, Carlos de Paula Eduardo
BACKGROUND AND OBJECTIVE: Stevens-Johnson syndrome (SJS) is a life-threatening dermatosis characterized by epidermal sloughing and stomatitis. We report the case of a 7-year-old boy in whom laser phototherapy (LPT) was highly effective in reversing the effects of an initial episode of SJS that had apparently developed in association with treatment with phenobarbital for a seizure disorder. The patient was first seen in the intensive care unit (ICU) of our institution with fever, cutaneous lesions on his extremities, trunk, face, and neck; mucosal involvement of his genitalia and eyes (conjunctivitis); ulcerative intraoral lesions; and swollen, crusted, and bleeding lips...
January 2011: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/20548897/a-case-of-neutrophilic-dermatosis-of-the-dorsal-hands-with-concomitant-involvement-of-the-lips
#15
Ji Won Byun, Won Kyu Hong, Hee Jin Song, Sung Hyub Han, Hyeon Sook Lee, Gwang Seong Choi, Jeong Hyun Shin
Neutrophilic dermatosis of the dorsal hands (NDDH) is a localized, pustular variant of acute febrile neutrophilic dermatosis (Sweet syndrome). The lesions of NDDH clinically resemble those of Sweet syndrome (SS), but they differ from classic SS according to their locations (NDDH is predominantly restricted to the dorsal hands) and the smaller number of accompanying systemic symptoms. The histology of the NDDH lesion shows a dense dermal neutrophilic infiltration. The lesions rapidly resolve after systemic corticosteroid and/or dapsone therapy...
February 2010: Annals of Dermatology
https://www.readbyqxmd.com/read/20523813/a-case-of-eczema-herpeticum-with-hailey-hailey-disease
#16
Gun Hong Lee, Yun Mi Kim, Sung Yul Lee, Jong Suk Lee, Young Lip Park, Kyu Uang Whang
Eczema herpeticum is the dissemination of herpes simplex virus in the setting of a preexisting skin disease. Hailey-Hailey disease [familial benign chronic pemphigus] is a blistering dermatosis that is inherited as an autosomal dominant trait and it usually presents itself around the third or fourth decades. Coexistence of eczema herpeticum and Hailey-Hailey disease is an infrequent occurrence. Four such cases have been reported in the English and German medical literature. We report here on an unusual case of eczema herpeticum that coexisted with Hailey-Hailey disease in a 47 years old man and we review the relevant literatures...
August 2009: Annals of Dermatology
https://www.readbyqxmd.com/read/20456722/clinical-and-immunological-heterogeneity-of-canine-subepidermal-blistering-dermatoses-with-anti-laminin-332-laminin-5-auto-antibodies
#17
Thierry Olivry, Petra Bizikova, Stanley M Dunston, Ross Bond, Richard Halliwell, Anette Loeffler, Cherie M Pucheu-Haston, Mei Chen, M Peter Marinkovich
Laminin-332 (laminin-5) is a basement membrane heterotrimeric protein composed of alpha-3, beta-3 and gamma-2 laminin chains. Laminin-332 polypeptides are targeted by auto-antibodies in human patients with mucous membrane (cicatricial) pemphigoid or, more rarely, subepidermal vesicular diseases that resemble epidermolysis bullosa acquisita (EBA) or bullous pemphigoid (BP). The objectives of this report were to characterize the clinical, histopathological and immunological characteristics of nine dogs with auto-antibodies targeting laminin-332...
August 2010: Veterinary Dermatology
https://www.readbyqxmd.com/read/19588060/a-newborn-with-bullous-pemphigoid-associated-with-linear-iga-bullous-dermatosis
#18
M A Akin, T Gunes, L Akýn, B Ohyama, O Kontas, T Hashimoto
A 16-day-old boy was admitted to our clinic with localized blisters on the neck, cheeks, earlobes, and oral cavity and with erythema on the toes, in addition to poor weight gain and respiratory distress. A physical examination revealed several erythematous plaques with tense bullae, multiple vesicles, and erosions on the left toes, neck, earlobes, and face as well as erosive lesions on the anterior part of the oral cavity, lips, and buccal mucosae. A bronchoscopic examination revealed bullous lesions in the upper respiratory tract and on the epiglottis...
June 2009: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
https://www.readbyqxmd.com/read/19120770/linear-iga-dermatosis-report-of-an-infantile-case-and-analysis-of-213-cases-in-japan
#19
REVIEW
Yuji Horiguchi, Akihiko Ikoma, Rie Sakai, Asako Masatsugu, Miyuki Ohta, Takashi Hashimoto
A 3-year-old boy presented with multiple vesicles, showing a rosette-like arrangement around the crusts. Histopathological and immunohistochemical examinations demonstrated subepidermal blistering with neutrophilic infiltration associated with deposition of IgA, but not IgG, linearly distributed along the basement membrane zone (BMZ) of the epidermis. Indirect immunofluorescence revealed circulating antibodies (IgA class, x160) against the BMZ of guinea pig lip skin. Based on the diagnosis of linear IgA dermatosis (LAD) of childhood, administration of dexamethasone (2 mg/day) was started, and the eruptions diminished immediately...
November 2008: Journal of Dermatology
https://www.readbyqxmd.com/read/19061654/-pyodermatitis-pyostomatitis-vegetans-with-nasal-involvement
#20
L Peuvrel, S Barbarot, V Gagey-Caron, M-H Tessier, E Cassagnau, J-F Stalder
BACKGROUND: Pyodermatitis-pyostomatitis vegetans (PPV) is a rare chronic disorder often associated with inflammatory bowel disease. We report an isolated case involving the oral, labial and nasal mucosa. PATIENTS AND METHODS: A 28-year-old man, in good general condition, presented with a 2-year history of painless stomatitis. The physical examination revealed pustular and exophytic lesions of the jugal, gingival and palatine mucosa on an erythematous background, as well as some pustular and crusted lesions of the lower lip and nostrils...
November 2008: Annales de Dermatologie et de Vénéréologie
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