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https://www.readbyqxmd.com/read/28303213/3d-nanomolding-and-fluid-mixing-in-micromixers-with-micro-patterned-microchannel-walls
#1
Bahador Farshchian, Alborz Amirsadeghi, Junseo Choi, Daniel S Park, Namwon Kim, Sunggook Park
Microfluidic devices where the microchannel walls were decorated with micro and nanostructures were fabricated using 3D nanomolding. Using 3D molded microfluidic devices with microchannel walls decorated with microscale gratings, the fluid mixing behavior was investigated through experiments and numerical simulation. The use of microscale gratings in the micromixer was predicated by the fact that large obstacles in a microchannel enhances the mixing performance. Slanted ratchet gratings on the channel walls resulted in a helical flow along the microchannel, thus increasing the interfacial area between fluids and cutting down the diffusion length...
2017: Nano Converg
https://www.readbyqxmd.com/read/28254551/in-silico-identification-of-a-therapeutic-target-for-photo-activated-disinfection-with-indocyanine-green-modeling-and-virtual-screening-analysis-of-arg-gingipain-from-porphyromonas-gingivalis
#2
Maryam Pourhajibagher, Abbas Bahador
BACKGROUND: Porphyromonas gingivalis is a momentous bacterial etiological agent associated with periodontitis, peri-implantitis as well as endodontic infections. The potential advantage of Photo-activated disinfection (PAD) as a promising novel approach is the choice of a suitable target site, specific photosensitizer, and wavelength of light for delivery of the light from source to target. Since Arg-gingipain is a cysteine proteinase that is involved in the virulence of P. gingivalis, it was evaluated as a target site for PAD with indocyanine green (ICG) as a photosensitizer...
February 27, 2017: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/28253076/major-thought-restructuring-the-roles-of-different-prefrontal-cortical-regions
#3
Shima Seyed-Allaei, Zahra Nasiri Avanaki, Bahador Bahrami, Tim Shallice
An important question for understanding the neural basis of problem solving is whether the regions of human prefrontal cortices play qualitatively different roles in the major cognitive restructuring required to solve difficult problems. However, investigating this question using neuroimaging faces a major dilemma: either the problems do not require major cognitive restructuring, or if they do, the restructuring typically happens once, rendering repeated measurements of the critical mental process impossible...
March 2, 2017: Journal of Cognitive Neuroscience
https://www.readbyqxmd.com/read/28251109/effect-of-hydroalcoholic-extract-of-echinacea-purpurea-in-combination-with-meglumine-antimoniate-on-treatment-of-leishmania-major-induced-cutaneous-leishmaniasis-in-balb-c-mice
#4
Bahador Sarkari, Mobin Mohseni, Mahmoud Reza Moein, Reza Shahriarirad, Qasem Asgari
CONTEXT: Progressive resistance of Leishmania parasite to available drugs including, meglumine antimoniate, has been reported from various regions of the world, especially Iran. AIMS: This study was conducted to evaluate the effect of hydroalcoholic extract of Echinacea purpurea in a combination therapy with glucantime in the treatment of cutaneous leishmaniasis caused by Leishmania major. MATERIALS AND METHODS: Hydroalcoholic extract of E...
January 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/28249746/the-evaluation-of-cultivable-microbiota-profile-in-patients-with-secondary-endodontic-infection-before-and-after-photo-activated-disinfection
#5
Maryam Pourhajibagher, Roghayeh Ghorbanzadeh, Steven Parker, Nasim Chiniforush, Abbas Bahador
BACKGROUND: Secondary/persistent endodontic infection can be the outcome of failure of endodontic treatment. Photo-activated disinfection (PAD) can be a useful adjunct to mechanical and antimicrobial agents in eliminating endopathogenic microorganisms. In this study, we evaluated the effect of PAD on diversity and count of microbiota related to secondary/persistent endodontic infections. MATERIALS AND METHODS: Root canal samples were taken using sterile paper points from the root canals of 14 patients with secondary/persistent endodontic infections after removing the root-canal filling materials...
February 26, 2017: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/28238067/acquisition-of-tn6018-3-cs-regions-increases-colistin-mics-against-acinetobacter-baumannii-isolates-harboring-new-variants-of-abars
#6
Mohammad Savari, Alireza Ekrami, Saeed Shoja, Abbas Bahador
Colistin is the last hope to treat extensively drug resistance (XDR) Acinetobacter baumannii (A. baumannii) infections, but resistance to colistin is currently reported in clinical centers all over the world. Here, we studied two colistin-resistant A. baumannii isolates with a difference in minimum inhibitory concentrations (MICs) that were isolated from a single burn patient during treatment in the hospitalization period. The international clonal (IC) lineage, multilocus sequence typing (MLST), and multiple loci variable number tandem repeat (VNTR) analysis (MLVA) typing were used to characterize the relatedness of A...
February 25, 2017: Folia Microbiologica
https://www.readbyqxmd.com/read/28216095/real-time-quantitative-reverse-transcription-pcr-analysis-of-expression-stability-of-aggregatibacter-actinomycetemcomitans-fimbria-associated-gene-in-response-to-photodynamic-therapy
#7
Maryam Pourhajibagher, Abbas Monzavi, Nasim Chiniforush, Mohammad Moein Monzavi, Shaghayegh Sobhani, Sima Shahabi, Abbas Bahador
BACKGROUND: Aggregatibacter actinomycetemcomitans is an etiological agent of both chronic and aggressive periodontitis. Dissemination of A. actinomycetemcomitans from the oral cavity and initiation of systemic infections has led to new approaches for treatment being needed. In this study, a series of experiments presented investigated the effect of methylene blue (MB)-mediated antimicrobial photodynamic therapy (aPDT) on cell viability and expression of fimbria-associated gene (rcpA) in A...
February 16, 2017: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/28215171/oral-colonization-by-nosocomial-pathogens-during-hospitalization-in-invasive-care-unit-and-prevention-strategies
#8
Hossein Kazemian, Samane Bourbour, Maryam Beheshti, Abbas Bahador
BACKGROUND: Critically ill patients are very susceptible to a variety of disorders and infections during hospitalization in Intensive Care Units (ICU). Among these problems, nosocomial infections are major causes of morbidity and mortality. METHODS: Nosocomial pneumonias, specifically ventilator associated pneumonias have become a major health care issue. The implication of oral care in hospital presents challenges that can prevent or reduce the risk of nosocomial pneumonias in ICU...
February 15, 2017: Recent Patents on Anti-infective Drug Discovery
https://www.readbyqxmd.com/read/28188945/assessment-of-clinical-teachers-professionalism-in-iran-from-residents-and-fellowships-perspective
#9
Sima Garshasbi, Hamidollah Bahador, Nahid Fakhraei, Abolfazl Farbod, Maryam Mohammadi, Soleiman Ahmady, Seyed Hassan Emami Razavi
In the present study, professional conduct of clinical teachers in Tehran University of Medical Sciences in Iran was assessed by their residents (n=292) and fellowships (n=48) using a standard questioner called self-reported measurement equipment. This evaluation was a descriptive cross-sectional study. Professionalism was questioned in four domains including clinical teacher-patient, clinical teacher-student, inter-professional and clinical teacher-self relationships. Accordingly, mean scores of the teachers in cases of clinical teacher-patient; clinical teacher-student, inter-professional (teamwork) and clinical teacher-self relations were 61%, 62...
January 2017: Acta Medica Iranica
https://www.readbyqxmd.com/read/28186433/production-of-monoclonal-antibody-against-excretory-secretory-antigen-of-fasciola-hepatica-and-evaluation-of-its-efficacy-in-the-diagnosis-of-fascioliasis
#10
Samaneh Abdolahi Khabisi, Bahador Sarkari, Abdolali Moshfe, Sedigheh Jalali
Parasitological methods are not helpful for the diagnosis of fascioliasis in acute and invasive periods of the disease. Detection of coproantigens seems to be a suitable alternative approach in the diagnosis of fascioliasis. The present study aimed to develop a reliable antigen detection system, using monoclonal antibodies raised against excretory-secretory (ES) antigen of Fasciola hepatica, for the diagnosis of fascioliasis. Fasciola adult worms were collected from the bile ducts of infected animals. Species of the fluke was determined by polymerase chain reaction-restriction fragment length polymorphism (RFLP-PCR)...
February 2017: Monoclonal Antibodies in Immunodiagnosis and Immunotherapy
https://www.readbyqxmd.com/read/28184326/does-endurance-training-compensate-for-neurotrophin-deficiency-following-diabetic-neuropathy
#11
Rasoul Eslami, Reza Gharakhanlou, Abdolreza Kazemi, Amir Bahador Dakhili, Ghazaleh Sorkhkamanzadeh, Ayob Sheikhy
BACKGROUND: A lack of neurotrophic support is believed to contribute to the development of diabetic neuropathy. On the other hand, neurotrophins have consistently been shown to increase in the central and peripheral nervous system following exercise, but the effects of exercise intervention on brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) in diabetic neuropathy are not understood. OBJECTIVES: This experimental study was designed and carried out at the Tarbiat Modares university (TMU) in Tehran, Iran, to investigate the hypothesis that increased activity as endurance training can help to increase the endogenous expression of neurotrophins in diabetic rats...
October 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/28144463/drug-reaction-with-eosinophilia-and-systemic-symptoms-induced-by-valproic-acid-a-case-report
#12
Mahboubeh Darban, Bahador Bagheri
INTRODUCTION: Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare but life-threatening reaction to drugs such as carbamazepine and allopurinol. The condition is characterized by skin rashes, fever, hematological disturbances, lymphadenopathy, and organ failure, most probably hepatic dysfunction. To date, only a few cases of valproate-induced DRESS syndrome have been reported. CASE PRESENTATION: We report on the case of a 60-year-old man who had been treated with valproic acid some time before being referred to Kowsar Hospital, Semnan, Iran in December 2015...
September 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/28137509/plasmid-borne-carbapenem-hydrolyzing-class-d-%C3%AE-lactamases-chdls-and-adeabc-efflux-pump-conferring-carbapenem-tigecycline-resistance-among-acinetobacter-baumannii-isolates-harboring-tnabars
#13
Mohammad Savari, Alireza Ekrami, Saeed Shoja, Abbas Bahador
Here we studied the prevalence and mechanisms of simultaneous resistance to carbapenem and tigecycline and accumulation of resistance determinants reservoirs in genome of Acinetobacter baumannii (A. baumannii) clinical isolates. Susceptibility of the isolates were measured to 18 antimicrobial agents. Genetic diversity of the microbial population was determined using the International Clonal lineage typing (IC typing), multiple locus VNTR analysis (MLVA) and plasmid profiling methods. To detect the AbaRs, Carbapenem-Hydrolyzing Class D β-Lactamases (CHDLs) genes, AdeABC efflux pump genes and resistance determinants, PCR was used...
March 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28127372/clinical-and-molecular-evaluation-of-a-case-of-giant-primary-splenic-hydatid-cyst-a-case-report
#14
Bahador Sarkari, Asieh Fatemie Sfedan, Abdolali Moshfe, Samaneh Abdolahi Khabisi, Amir Savardashtaki, Farshad Hosseini, Ardavan Shahbazi
Spleen is an unusual location for hydatid cyst. Here we report a case of primary splenic hydatid cyst in a 41-yr-old Iranian woman from Yasuj, southwest of Iran. The patient had been admitted to Shahid Beheshti Hospital because of abdominal pain. Abdominal sonography revealed a hypoechoic lesion of 150 X 130 mm in the spleen, suggestive of hydatid cyst. Splenectomy was performed for the patient and surgical interventions revealed a hydatid cyst occupying most of splenic parenchyma. She was discharged on the 5 day of her operation...
October 2016: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/28127344/helminth-parasites-of-wild-boars-sus-scrofa-in-bushehr-province-southwestern-iran
#15
Majid Mansouri, Bahador Sarkari, Gholam Reza Mowlavi
BACKGROUND: Wild boars, Sus scrofa, of wide distribution considered as a potential source of zoonotic parasites. The current study aimed to assess the prevalence of helminth infections in wild boars in the Persian Gulf coastal area (Bushehr Province), Southwestern Iran. METHODS: Twenty-five wild boars, including 11 males and 14 females, were collected during a course of vertebrate pest control in the Bushehr Province, southwestern Iran in 2013. The specimen were immediately dissected and carefully searched for the parasites...
July 2016: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/28127332/effect-of-addition-of-curcumin-nanoparticles-on-antimicrobial-property-and-shear-bond-strength-of-orthodontic-composite-to-bovine-enamel
#16
Ahmad Sodagar, Abbas Bahador, Maryam Pourhajibagher, Badreddin Ahmadi, Pedram Baghaeian
OBJECTIVES: This study sought to assess the effect of curcumin nanoparticles (curcNPs) on antimicrobial property and shear bond strength (SBS) of orthodontic composite to bovine enamel. MATERIALS AND METHODS: In this in vitro, experimental study, 1%, 5% and 10% curcNPs were added to Transbond XT composite. Stainless steel brackets were bonded to 48 sound bovine incisors in four groups (n=12) using composite containing 0% (control), 1%, 5% and 10% curcNPs. The bracket-tooth SBS was measured by a universal testing machine...
September 2016: Journal of Dentistry of Tehran University of Medical Sciences
https://www.readbyqxmd.com/read/28127324/effect-of-postoperative-amoxicillin-on-early-bacterial-colonization-of-peri-implant-sulcus-a-randomized-controlled-clinical-trial
#17
Neda Moslemi, Aysan Shahnaz, Abbas Bahador, Sepehr Torabi, Sanaa Jabbari, Zahra Alizadeh Oskouei
OBJECTIVES: With side effects of antibiotics taken into consideration, the necessity of antibiotic therapy after simple implant placement procedures is still a subject of debate and the existing literature on this topic is widely controversial. The aim of this study was to assess the effect of postoperative amoxicillin therapy on early colonization of peri-implant sulcus after implant placement. MATERIALS AND METHODS: In this randomized controlled clinical trial, 20 patients requiring simple implant placement were randomly allocated to test or control groups and received postoperative amoxicillin or placebo, respectively...
September 2016: Journal of Dentistry of Tehran University of Medical Sciences
https://www.readbyqxmd.com/read/28065582/bivalent-flagellin-immunotherapy-protects-mice-against-pseudomonas-aeruginosa-infections-in-both-acute-pneumonia-and-burn-wound-models
#18
Hosein Ahmadi, Bahador Behrouz, Gholamreza Irajian, Nour Amirmozafari, Sara Naghavi
Pseudomonas aeruginosa infections are a serious challenge to therapy because of the complex pathogenesis and paucity of new effective antibiotics, thus renewing interest in antibody-based therapeutic strategies. Immunotherapy strategies typically target selected virulence factors that are expressed by the majority of clinical strains of P. aeruginosa, particularly because virulence factors mediate infection. Type a and b flagellins (flagellin a+b) of P. aeruginosa are acute virulence factors that play a major role in the establishment of infection...
January 5, 2017: Biologicals: Journal of the International Association of Biological Standardization
https://www.readbyqxmd.com/read/28032108/faunal-distribution-and-seasonal-bio-ecology-of-naturally-infected-sand-flies-in-a-new-endemic-zoonotic-cutaneous-leishmaniasis-focus-of-southern-iran
#19
Kourosh Azizi, Hayedeh Parvinjahromi, Mohammad Djaefar Moemenbellah-Fard, Bahador Sarkari, Mohammad Reza Fakoorziba
BACKGROUND: Cutaneous leishmaniasis is a major health problem in Iran in spite of implementation of control program. This infectious disease caused morbidity in less than 27000 people in 2010. This study was set to determine some ecological aspects of sand flies in Fasa district, Fars Province, southern Iran during 2011-2012. METHODS: A total of 4792 sand flies were captured by means of sticky paper and CDC miniature light traps in 10 selected villages from the beginning to the end of the active season, from which 1115 specimens were captured for abundance study and 3677 specimens captured for monitoring monthly activities in Fasa...
December 2016: Journal of Arthropod-borne Diseases
https://www.readbyqxmd.com/read/27957297/perforated-meckel-s-diverticulum-in-a-3-day-old-neonate-a-case-report
#20
Mehdi Frooghi, Ali Bahador, Alireza Golchini, Mahmood Haghighat, Maryam Ataollahi, Hazhir Javaherizadeh
Perforation of Meckel's diverticulum is a rare complication in neonatal period. A 3-dayold term male neonate was transferred to our emergency room due to bowel perforation. Surgical exploration was done and perforated Meckel's diverticulum was detected. Pathological report of the tissue showed inflamed diverticulum with heterotopic gastric mucosa. This is the first report of Meckel's diverticulum perforation in a neonate in our country.
October 2016: Middle East Journal of Digestive Diseases
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