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https://www.readbyqxmd.com/read/29148098/absence-or-mislocalization-of-dnah5-is-a-characteristic-marker-for-motile-ciliary-abnormality-in-nasal-polyps
#1
Qianhui Qiu, Yang Peng, Zhenchao Zhu, Zhuo Chen, Chi Zhang, Hsiao Hui Ong, Kai Sen Tan, Haiyu Hong, Yan Yan, Haoqi Huang, Jing Liu, Xianqing Li, H N Nam, N T N Dung, Li Shi, Qintai Yang, Colin D Bingle, De-Yun Wang
OBJECTIVE: Motile cilia impairment is a common condition in patients with chronically inflamed airways, such as is seen in nasal polyps (NPs). The mechanism underlying this pathogenic condition is complex and not fully understood. METHODS: We investigated the presence and localization of dynein axonemal heavy chain 5 (DNAH5) in motile cilia using immunofluorescence staining in paraffin-embedded nasal biopsies from NPs (n = 120) and inferior turbinate mucosa (n = 35) of healthy controls...
November 17, 2017: Laryngoscope
https://www.readbyqxmd.com/read/29145003/the-importance-of-saprinus-semistriatus-coleoptera-histeridae-for-estimating-the-minimum-post-mortem-interval
#2
I Szelecz, N Feddern, C V W Seppey, J Amendt, E A D Mitchell
In forensic science, the use of entomological evidence to estimate the minimum post-mortem interval can be crucial. However, not all cadaver-visiting insects are equally useful. Our focus is on the histerid beetle Saprinus semistriatus (Scriba 1790) (Histeridae; Coleoptera). Histeridae are common predators that feed mainly on dipteran larvae on carrion and dung. We review 23 publications mentioning this species and provide new experimental data on its temporal pattern beneath and on hanging pig cadavers. In a field experiment near Neuchâtel, Switzerland, we recorded the abundance of S...
November 10, 2017: Legal Medicine
https://www.readbyqxmd.com/read/29140404/evaluation-of-opportunities-to-improve-hematopathology-diagnosis-for-vietnam-pathologists
#3
Vanessa Dayton, Chi Kim Nguyen, Trinh Thu Van, Nguyen Van Thanh, Ta Van To, Nguyen Phi Hung, Nguyen Ngoc Dung, Danny A Milner
Objectives: We evaluate the need for, feasibility of, and impediments to improving hematopathology diagnoses for cancer hospitals in Vietnam. Methods: Two hematopathologists from the United States visited three major cancer treatment hospitals in Vietnam to workshop a sampling of difficult hematopathology cases. With Vietnamese pathologists, they toured histopathology, immunohistochemistry, and ancillary laboratory facilities. Results: Automated tissue processors and slide staining equipment were documented for each of the three hospitals...
November 11, 2017: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/29139533/at-the-very-beginning-of-life-on-earth-the-thiol-rich-peptide-trp-world-hypothesis
#4
Yannick Vallee, Ibrahim Shalayel, Kieu-Dung Ly, K V Raghavendra Rao, Gael De Paëpe, Katharina Märker, Anne Milet
Life developed on Earth probably about 3.8 billion years ago, on a planet that was already largely covered by oceans and where the atmosphere was very humid. The reactions, which may have led to the formation of the first polymers, particularly to the first peptides and nucleic acids, must have been compatible with these conditions. This is the case of the reaction of nitriles with aminothiols, such as cysteine and homocysteine. Since aminonitriles are the probable precursors of amino acids, this condensation reaction has been able to rapidly yield dipeptides, tripeptides, oligomers and even true polymers, each containing thiol functions...
2017: International Journal of Developmental Biology
https://www.readbyqxmd.com/read/29138432/social-support-as-a-key-protective-factor-against-depression-in-hiv-infected-patients-report-from-large-hiv-clinics-in-hanoi-vietnam
#5
Shoko Matsumoto, Kazue Yamaoka, Kenzo Takahashi, Junko Tanuma, Daisuke Mizushima, Cuong Duy Do, Dung Thi Nguyen, Hoai Dung Thi Nguyen, Kinh Van Nguyen, Shinichi Oka
Depression is the most common mental health issue among people living with HIV/AIDS (PLWHA). This study explored how different types and sources of social support are associated with depression among HIV-infected patients in Vietnam. We carried out a cross-sectional survey on 1,503 HIV-infected patients receiving antiretroviral therapy at two HIV clinics in Hanoi in 2016. Depression was prevalent in 26.2% of participants. Higher score of social support, especially emotional/informational support and positive social interaction, showed significant association with lower depression rate...
November 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29135894/deferoxamine-preconditioning-of-irradiated-tissue-improves-perfusion-and-fat-graft-retention
#6
John Flacco, Natalie Chung, Charles P Blackshear, Dre Irizarry, Arash Momeni, Gordon K Lee, Dung Nguyen, Geoffrey C Gurtner, Michael T Longaker, Derrick C Wan
BACKGROUND: Radiation therapy is a mainstay in the treatment of many malignancies, but collateral damage to surrounding tissue, with resultant hypovascularity, fibrosis, and atrophy, can be difficult to reconstruct. Fat grafting has been shown to improve the quality of irradiated skin, but volume retention of the graft is significantly decreased. Deferoxamine (DFO) is a FDA-approved iron-chelating medication for acute iron intoxication and chronic iron overload that has also been shown to increase angiogenesis...
November 8, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29134142/assemblage-and-functional-categorization-of-dung-beetles-coleoptera-scarabaeinae-from-the-pantanal
#7
Marcelo B Pessôa, Thiago J Izzo, Fernando Z Vaz-de-Mello
The Pantanal is one of the world's largest tropical wetland areas and harbors high mammal biomass. There is no formal list of dung beetle species, and studies on their functional roles have never being carried out in Pantanal. In this study, we identified dung beetle species occurring in the north Pantanal region (Poconé sub-region, Brazil) and studied their functional organization, by measuring morphological, behavioral and phenological traits. We collected 25,278 individuals belonging to 17 genera and 35 species...
2017: PeerJ
https://www.readbyqxmd.com/read/29134024/hidden-in-the-urban-parks-of-new-york-city-themira-lohmanus-a-new-species-of-sepsidae-described-based-on-morphology-dna-sequences-mating-behavior-and-reproductive-isolation-sepsidae-diptera
#8
Yuchen Ang, Gowri Rajaratnam, Kathy Fy Su, Rudolf Meier
New species from well-studied taxa such as Sepsidae (Diptera) are rarely described from localities that have been extensively explored and one may think that New York City belongs to this category. Yet, a new species of Themira (Diptera: Sepsidae) was recently discovered which is currently only known to reside in two of New York City's largest urban parks. Finding a new species of Themira in these parks was all the more surprising because the genus was revised in 1998 and is not particularly species-rich (13 species)...
2017: ZooKeys
https://www.readbyqxmd.com/read/29128770/ivermectin-residues-disrupt-dung-beetle-diversity-soil-properties-and-ecosystem-functioning-an-interdisciplinary-field-study
#9
José R Verdú, Jorge M Lobo, Francisco Sánchez-Piñero, Belén Gallego, Catherine Numa, Jean-Pierre Lumaret, Vieyle Cortez, Antonio J Ortiz, Mattia Tonelli, Juan P García-Teba, Ana Rey, Alexandra Rodríguez, Jorge Durán
Ivermectin is the most common endectocide used to control parasites affecting livestock. Short-term physiological and behavioural effects of ivermectin on dung beetles may have long-term consequences for beetle populations and ecosystem functioning. Long-term effects of the use of ivermectin can be estimated by comparing dung assemblages and ecosystem functions in areas with conventional ivermectin-treated livestock and environmentally similar areas in which livestock are not treated with veterinary medical products (organic farming)...
November 9, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29127227/protocol-for-hospital-based-surveillance-of-cerebral-palsy-cp-in-hanoi-using-the-paediatric-active-enhanced-disease-surveillance-mechanism-paeds-vietnam-a-study-towards-developing-hospital-based-disease-surveillance-in-vietnam
#10
Gulam Khandaker, Nguyen Van Bang, Trịnh Quang Dũng, Nguyen Thi Huong Giang, Cao Minh Chau, Nguyen Thi Van Anh, Nguyen Van Thuong, Nadia Badawi, Elizabeth J Elliott
INTRODUCTION: The epidemiology, pathogenesis, management and outcomes of cerebral palsy (CP) in low-income and middle-income countries including Vietnam are unknown because of the lack of mechanisms for standardised collection of data. In this paper, we outline the protocol for developing a hospital-based surveillance system modelled on the Paediatric Active Enhanced Disease Surveillance (PAEDS) system in Australia. Using PAEDS-Vietnam we will define the aetiology, motor function and its severity, associated impairments, and nutritional and rehabilitation status of children with CP in Hanoi, Vietnam...
November 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/29126174/mirtarbase-update-2018-a-resource-for-experimentally-validated-microrna-target-interactions
#11
Chih-Hung Chou, Sirjana Shrestha, Chi-Dung Yang, Nai-Wen Chang, Yu-Ling Lin, Kuang-Wen Liao, Wei-Chi Huang, Ting-Hsuan Sun, Siang-Jyun Tu, Wei-Hsiang Lee, Men-Yee Chiew, Chun-San Tai, Ting-Yen Wei, Tzi-Ren Tsai, Hsin-Tzu Huang, Chung-Yu Wang, Hsin-Yi Wu, Shu-Yi Ho, Pin-Rong Chen, Cheng-Hsun Chuang, Pei-Jung Hsieh, Yi-Shin Wu, Wen-Liang Chen, Meng-Ju Li, Yu-Chun Wu, Xin-Yi Huang, Fung Ling Ng, Waradee Buddhakosai, Pei-Chun Huang, Kuan-Chun Lan, Chia-Yen Huang, Shun-Long Weng, Yeong-Nan Cheng, Chao Liang, Wen-Lian Hsu, Hsien-Da Huang
MicroRNAs (miRNAs) are small non-coding RNAs of ∼ 22 nucleotides that are involved in negative regulation of mRNA at the post-transcriptional level. Previously, we developed miRTarBase which provides information about experimentally validated miRNA-target interactions (MTIs). Here, we describe an updated database containing 422 517 curated MTIs from 4076 miRNAs and 23 054 target genes collected from over 8500 articles. The number of MTIs curated by strong evidence has increased ∼1.4-fold since the last update in 2016...
November 6, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/29121870/trends-in-newborn-umbilical-cord-care-practices-in-sokoto-and-bauchi-states-of-nigeria-the-where-who-how-what-and-the-ubiquitous-role-of-traditional-birth-attendants-a-lot-quality-assurance-sampling-survey
#12
Dele Abegunde, Nosa Orobaton, Katherine Beal, Amos Bassi, Moyosola Bamidele, Toyin Akomolafe, Francis Ohanyido, Olayinka Umar-Farouk, Saba'atu Danladi
BACKGROUND: Neonatal infections caused by unsafe umbilical cord practices account for the majority of neonatal deaths in Nigeria. We examined the trends in umbilical cord care practices between 2012 and 2015 that coincided with the introduction of chlorhexidine digluconate 7.1% gel in Bauchi and Sokoto States. METHODS: We obtained data from three rounds of lot quality assurance samples (LQAS) surveys conducted in 2012, 2013 and 2015. Households were randomly sampled in each round that totaled 1140 and 1311 households in Bauchi and Sokoto States respectively...
November 9, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29117990/simultaneous-physiologically-based-pharmacokinetic-pbpk-modeling-of-parent-and-active-metabolites-to-investigate-complex-cyp3a4-drug-drug-interaction-potential-a-case-example-of-midostaurin
#13
Helen Gu, Catherine Dutreix, Sam Rebello, Taoufik Ouatas, Lai Wang, Dung Yu Chun, Heidi J Einolf, Handan He
Midostaurin (PKC412) is being investigated for the treatment of acute myeloid leukemia (AML) and advanced systemic mastocytosis (advSM). It is extensively metabolized by cytochrome P450 (CYP) 3A4 to form 2 major active metabolites, CGP52421 and CGP62221. In vitro and clinical drug-drug interaction (DDI) studies indicated that midostaurin and its metabolites are substrates, reversible and time-dependent inhibitors, and inducers of CYP3A4. A simultaneous pharmacokinetic model of parent and active metabolites was initially developed by incorporating data from in vitro, preclinical, and clinical pharmacokinetic studies in healthy volunteers and in patients with AML or advSM...
November 8, 2017: Drug Metabolism and Disposition: the Biological Fate of Chemicals
https://www.readbyqxmd.com/read/29111908/misuse-of-antenatal-care-and-its-association-with-adverse-outcomes-of-pregnancy-in-a-southern-rural-area-of-vietnam
#14
Thi-Thuy-Dung Ngo, The-Dung Nguyen, Philippe Goyens, Annie Robert
Researchers in Vietnam reported a high percentage of pregnant women attending ANC at least once, but an insufficient utilization of ANC services remains. The evidence demonstrating how the utilization of these services affect pregnancy outcome is not documented in Vietnam. We investigated the association between the misuse of ANC services and pregnancy outcome, and assessed other determinants associated with ANC services utilization. We conducted a prospective community-based study in Trang Bom district, Dong Nai, during 12 consecutive months...
November 7, 2017: Health Care for Women International
https://www.readbyqxmd.com/read/29110709/the-prevalence-incidence-and-prevention-of-plasmodium-falciparum-infections-in-forest-rangers-in-bu-gia-map-national-park-binh-phuoc-province-vietnam-a-pilot-study
#15
Do Hung Son, Nguyen Thuy-Nhien, Lorenz von Seidlein, Truong Le Phuc-Nhi, Ngo Thi Phu, Nguyen Thi Kim Tuyen, Nguyen Huyen Tran, Nguyen Van Dung, Bui Van Quan, Nicholas P J Day, Arjen M Dondorp, Nicholas J White, Guy E Thwaites, Tran Tinh Hien
BACKGROUND: Prophylaxis for high-risk populations, such as forest workers, could be one component for malaria elimination in the Greater Mekong Sub-region. A study was conducted to assess the malaria incidence in forest rangers and the feasibility of malaria prophylaxis for rangers sleeping in forest camps. METHODS: Forest rangers deployed in the Bu Gia Map National Park, Vietnam were invited to participate in the study. Plasmodium infections were cleared using presumptive treatment, irrespective of malaria status, with a 3-day course dihydroartemisinin/piperaquine (DP) and a 14-day course of primaquine...
November 6, 2017: Malaria Journal
https://www.readbyqxmd.com/read/29101880/in-situ-observation-of-phase-transformation-in-iron-carbide-nanocrystals
#16
Le Thanh Cuong, Nguyen Duc Dung, Ta Quoc Tuan, Nguyen Thi Khoi, Pham Thanh Huy, Ngo Ngoc Ha
This paper reports on the in situ observation of phase transformation in an iron carbide nanocrystal encapsulated in a graphitic shell by means of high resolution transmission electron microscopy (HR-TEM). A Fe7C3 nanocrystal in orthorhombic (o-Fe7C3) structure with carbon graphitic cover is captured at the initial time of the experiment. Under the projection of a high-energy electron beam (200kV), the graphitic carbon layer evaporates gradually and structural changes in orthorhombic (o-Fe7C3) crystal manifests simultaneously...
October 31, 2017: Micron: the International Research and Review Journal for Microscopy
https://www.readbyqxmd.com/read/29100656/diversity-and-bioactivities-of-nostocacean-cyanobacteria-isolated-from-paddy-soil-in-vietnam
#17
Hang T L Pham, Lien T T Nguyen, Tuan A Duong, Dung T T Bui, Que T Doan, Ha T T Nguyen, Sabine Mundt
Nostocacean cyanobacteria are one of the important components of paddy fields due to their ability to fix atmospheric nitrogen and supply phytohormones for crop growth. In this study, 13 Nostoc strains isolated from paddy soils in Vietnam were classified using a polyphasic approach. The results showed a high diversity of the isolated strains that represented seven morphotypes corresponding to five genotypes, with 16S rRNA gene sequence similarity values ranging between 94.97-99.78% compared to the available sequences from GenBank...
October 14, 2017: Systematic and Applied Microbiology
https://www.readbyqxmd.com/read/29099171/hollow-few-layer-graphene-based-structures-from-parafilm-waste-for-flexible-transparent-supercapacitors-and-oil-spill-cleanup
#18
Duc Dung Nguyen, Ping-Yen Hsieh, Meng-Ting Tsai, Chi-Young Lee, Nyan-Hwa Tai, Bao Dong To, Duc Tu Vu, Chia Chen Hsu
We report a versatile strategy to exploit parafilm waste as a carbon precursor for fabrication of freestanding, hollow few-layer graphene fiber mesh (HFGM) structures without use of any gaseous carriers/promoters via an annealing route. The freestanding HFGMs possess good mechanical flexibility, tailorable transparency, and high electrical conductivity, consequently qualifying them as promising electrochemical electrodes. Because of the hollow spaces, electrolyte ions can easily access into and contact with interior surfaces of the graphene fibers, accordingly increasing electrode/electrolyte interfacial area...
November 9, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29093750/bioprospecting-of-novel-thermostable-%C3%AE-glucosidase-from-bacillus-subtilis-ra10-and-its-application-in-biomass-hydrolysis
#19
Rameshwar Tiwari, Puneet Kumar Singh, Surender Singh, Pawan K S Nain, Lata Nain, Pratyoosh Shukla
Background: Saccharification is the most crucial and cost-intensive process in second generation biofuel production. The deficiency of β-glucosidase in commercial enzyme leads to incomplete biomass hydrolysis. The decomposition of biomass at high temperature environments leads us to isolate thermotolerant microbes with β-glucosidase production potential. Results: A total of 11 isolates were obtained from compost and cow dung samples that were able to grow at 50 °C...
2017: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/29089167/mortality-burden-of-diurnal-temperature-range-and-its-temporal-changes-a-multi-country-study
#20
Whanhee Lee, Michelle L Bell, Antonio Gasparrini, Ben G Armstrong, Francesco Sera, Sunghee Hwang, Eric Lavigne, Antonella Zanobetti, Micheline de Sousa Zanotti Stagliorio Coelho, Paulo Hilario Nascimento Saldiva, Samuel Osorio, Aurelio Tobias, Ariana Zeka, Patrick G Goodman, Bertil Forsberg, Joacim Rocklöv, Masahiro Hashizume, Yasushi Honda, Yue-Liang Leon Guo, Xerxes Seposo, Do Van Dung, Tran Ngoc Dang, Shilu Tong, Yuming Guo, Ho Kim
Although diurnal temperature range (DTR) is a key index of climate change, few studies have reported the health burden of DTR and its temporal changes at a multi-country scale. Therefore, we assessed the attributable risk fraction of DTR on mortality and its temporal variations in a multi-country data set. We collected time-series data covering mortality and weather variables from 308 cities in 10 countries from 1972 to 2013. The temporal change in DTR-related mortality was estimated for each city with a time-varying distributed lag model...
January 2018: Environment International
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