Read by QxMD icon Read


Melanie Bannister-Tyrrell, Nguyen Xuan Xa, Johanna Helena Kattenberg, Nguyen Van Van, Vu Khac Anh Dung, Truong Minh Hieu, Nguyen Van Hong, Eduard Rovira-Vallbona, Nguyen Thanh Thao, Tran Thanh Duong, Anna Rosanas-Urgell, Koen Peeters Grietens, Annette Erhart
BACKGROUND: In Vietnam, malaria persists in remote forested regions where infections are spatially heterogeneous, mostly asymptomatic and with low parasite density. Previous studies in Vietnam have investigated broad behavioural concepts such as 'engaging in forest activities' as risk factors for malaria infection, which may not explain heterogeneity in malaria risk, especially in malaria elimination settings. METHODS: A mixed methods study combining ethnographic research and a cross-sectional survey was embedded in a 1-year malariometric cohort study in three ethnic minority villages in South Tra My district, Quang Nam Province in Central Vietnam...
March 19, 2018: Malaria Journal
Stephanie S Bauerfeind, Jesper G Sørensen, Volker Loeschcke, David Berger, E Dale Broder, Madeleine Geiger, Manuela Ferrari, Wolf U Blanckenhorn
Climatic conditions can be very heterogeneous even over small geographic scales, and are believed to be major determinants of the abundance and distribution of species and populations. Organisms are expected to evolve in response to the frequency and magnitude of local thermal extremes, resulting in local adaptation. Using replicate yellow dung fly (Scathophaga stercoraria; Diptera: Scathophagidae) populations from cold (northern Europe) and warm climates (southern Europe), we compared 1) responses to short-term heat and cold shocks in both sexes, 2) heat shock protein (Hsp70) expression in adults and eggs, and 3) female reproductive traits when facing short-term heat stress during egg maturation...
April 2018: Journal of Thermal Biology
Dung Xuan Nguyen, Tankut Can, Andrey Gromov
This corrects the article DOI: 10.1103/PhysRevLett.118.206602.
February 23, 2018: Physical Review Letters
Aymeric Monteillier, Pierre-Marie Allard, Katia Gindro, Jean-Luc Wolfender, Muriel Cuendet
Lung cancer is the most lethal form of cancer in the world. Its development often involves an overactivation of the nuclear factor kappa B (NF-κB) pathway, leading to increased cell proliferation, survival, mobility, and a decrease in apoptosis. Therefore, NF-κB inhibitors are actively sought after for both cancer chemoprevention and therapy, and fungi represent an interesting unexplored reservoir for such molecules. The aim of the present work was to find naturally occurring lung cancer chemopreventive compounds by investigating the metabolites of Penicillium vulpinum , a fungus that grows naturally on dung...
March 12, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Bryony Sands, Neludo Mgidiswa, Casper Nyamukondiwa, Richard Wall
Pyrethroid insecticides are widely used to control ectoparasites of livestock, particularly ticks and biting flies. Their use in African livestock systems is increasing, driven by the need to increase productivity and local food security. However, insecticide residues present in the dung after treatment are toxic to dung-inhabiting insects. In a semiarid agricultural habitat in Botswana, dung beetle adult mortality, brood ball production, and larval survival were compared between untreated cattle dung and cattle dung spiked with deltamethrin, to give concentrations of 0...
March 2018: Ecology and Evolution
Julian A Gingold, Dandan Zhu, Dung-Fang Lee, Ahmed Kaseb, Jian Chen
Hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (iCCA), the two most common primary liver cancers, represent the second most common cancer-related cause of death worldwide, with most cases being diagnosed at an advanced stage. Recent genome-wide studies have helped to elucidate the molecular pathogenesis and genetic heterogeneity of liver cancers. This review of the genetic landscape of HCC and iCCA discusses the most recent findings from genomic profiling and the current understanding of the pathways involved in the initiation and progression of liver cancer...
March 9, 2018: Trends in Molecular Medicine
Lisa-Maria Needham, Judith Weber, James W B Fyfe, Omaru M Kabia, Dung T Do, Ewa Klimont, Yu Zhang, Margarida Rodrigues, Christopher M Dobson, Sonia Ghandi, Sarah E Bohndiek, Thomas N Snaddon, Steven F Lee
Protein aggregation into amyloid deposits and oxidative stress are key features of many neurodegenerative disorders including Parkinson's and Alzheimer's disease. We report here the creation of four highly sensitive bifunctional fluorescent probes, capable of H2 O2 and/or amyloid aggregate detection. These bifunctional sensors use a benzothiazole core for amyloid localization and boronic ester oxidation to specifically detect H2 O2 . We characterized the optical properties of these probes using both bulk fluorescence measurements and single-aggregate fluorescence imaging, and quantify changes in their fluorescence properties upon addition of amyloid aggregates of α-synuclein and pathophysiological H2 O2 concentrations...
February 2018: Royal Society Open Science
Zhihong Zhang, Xiaoyang Wang, Jin Tong, Carr Stephen
A highly efficient soil-burrowing dung beetle possesses an intricate outer contour curve on its foreleg end-tooth. This study was carried out based on evidence that this special outer contour curve has the potential of reducing soil penetration resistance and could enhance soil-burrowing efficiency. A toothed wheel is a typical agricultural implement for soil imprinting, to increase its working efficiency; the approach of the bionic geometrical structure was utilized to optimize the innovative shape of imprinting toothed wheel...
2018: Applied Bionics and Biomechanics
Carla Lancelotti
Ancient civilisations depended heavily on natural fuel resources for a wide array of activities, and this had an impact on such resources that can be traced in the archaeological record. At its urban apex, the populations of the Indus Civilisation (2600-1900 BC) produced a wide range of objects and crafts, several of which involved highly specialised pyrotechnology. In the wake of increasing aridity and a period of weakened monsoon rainfall that affected South Asia from 2100 BC, these activities potentially put pressure on the natural resource base that may have had to be counterbalanced by differentiation in fuel use...
2018: PloS One
Phan Vuong Khac Thai, Dang Thi Minh Ha, Nguyen Thi Hanh, Jeremy Day, Sarah Dunstan, Nguyen Thi Quynh Nhu, Vo Sy Kiet, Nguyen Huu Lan, Nguyen Huy Dung, Nguyen Thi Ngoc Lan, Nguyen Thuong Thuong, Nguyen Ngoc Lan, Phạm Thị Thúy Liễu, Nguyễn Thị Hồng, Đào Công Điệp, Nguyễn Thị Kim Thanh, Nguyễn Văn Hội, Nguyễn Văn Nghĩa, Trương Ngọc Đại, Hoàng Quang Minh, Nguyễn Văn Thơm, Jeremy Farrar, Maxine Caws
BACKGROUND: Drug resistant tuberculosis (TB) is increasing in prevalence worldwide. Treatment failure and relapse is known to be high for patients with isoniazid resistant TB treated with standard first line regimens. However, risk factors for unfavourable outcomes and the optimal treatment regimen for isoniazid resistant TB are unknown. This cohort study was conducted when Vietnam used the eight month first line treatment regimen and examined risk factors for failure/relapse among patients with isoniazid resistant TB...
March 6, 2018: BMC Infectious Diseases
Alfonsina Arriaga-Jiménez, Matthias Rös, Gonzalo Halffter
Insect diversity patterns of high mountain ecosystems remain poorly studied in the tropics. Sampling dung beetles of the subfamilies Aphodiinae, Scarabaeinae, and Geotrupinae was carried out at four volcanoes in the Trans-Mexican Volcanic Belt (TMVB) in the Mexican transition zone at 2,700 and 3,400 MASL, and on the windward and leeward sides. Sampling units represented a forest-shrubland-pasture (FSP) mosaic typical of this mountain region. A total of 3,430 individuals of 29 dung beetle species were collected...
2018: PeerJ
P W Crous, M J Wingfield, T I Burgess, A J Carnegie, G E St J Hardy, D Smith, B A Summerell, J F Cano-Lira, J Guarro, J Houbraken, L Lombard, M P Martín, M Sandoval-Denis, A V Alexandrova, C W Barnes, I G Baseia, J D P Bezerra, V Guarnaccia, T W May, M Hernández-Restrepo, A M Stchigel, A N Miller, M E Ordoñez, V P Abreu, T Accioly, C Agnello, A Agustin Colmán, C C Albuquerque, D S Alfredo, P Alvarado, G R Araújo-Magalhães, S Arauzo, T Atkinson, A Barili, R W Barreto, J L Bezerra, T S Cabral, F Camello Rodríguez, R H S F Cruz, P P Daniëls, B D B da Silva, D A C de Almeida, A A de Carvalho Júnior, C A Decock, L Delgat, S Denman, R A Dimitrov, J Edwards, A G Fedosova, R J Ferreira, A L Firmino, J A Flores, D García, J Gené, A Giraldo, J S Góis, A A M Gomes, C M Gonçalves, D E Gouliamova, M Groenewald, B V Guéorguiev, M Guevara-Suarez, L F P Gusmão, K Hosaka, V Hubka, S M Huhndorf, M Jadan, Ž Jurjević, B Kraak, V Kučera, T K A Kumar, I Kušan, S R Lacerda, S Lamlertthon, W S Lisboa, M Loizides, J J Luangsa-Ard, P Lysková, W P Mac Cormack, D M Macedo, A R Machado, E F Malysheva, P Marinho, N Matočec, M Meijer, A Mešić, S Mongkolsamrit, K A Moreira, O V Morozova, K U Nair, N Nakamura, W Noisripoom, I Olariaga, R J V Oliveira, L M Paiva, P Pawar, O L Pereira, S W Peterson, M Prieto, E Rodríguez-Andrade, C Rojo De Blas, M Roy, E S Santos, R Sharma, G A Silva, C M Souza-Motta, Y Takeuchi-Kaneko, C Tanaka, A Thakur, M Th Smith, Z Tkalčec, N Valenzuela-Lopez, P van der Kleij, A Verbeken, M G Viana, X W Wang, J Z Groenewald
Novel species of fungi described in this study include those from various countries as follows: Antarctica : Cadophora antarctica from soil. Australia : Alfaria dandenongensis on Cyperaceae , Amphosoma persooniae on Persoonia sp., Anungitea nullicana on Eucalyptus sp . , Bagadiella eucalypti on Eucalyptus globulus , Castanediella eucalyptigena on Eucalyptus sp., Cercospora dianellicola on Dianella sp., Cladoriella kinglakensis on Eucalyptus regnans , Cladoriella xanthorrhoeae (incl. Cladoriellaceae fam. nov...
December 2017: Persoonia
Vuu My Dung, Dang Ngoc Anh Suong, Yuji Okamaoto, Yu Hiramatsu, Dang Thi Phuong Thao, Hideki Yoshida, Hiroshi Takashima, Masamitsu Yamaguchi
Pyruvate dehydrogenase complex deficiency (PDCD) is a common primary cause of defects in mitochondrial function and also can lead to peripheral neuropathy. Pyruvate dehydrogenase E1 component subunit beta (PDHB) is a subunit of pyruvate dehydrogenase E1, which is a well-known component of PDC. In Drosophila melanogaster, the CG11876 (dPDHB) gene is a homolog of human PDHB. In this study, we established a Drosophila model with neuron-specific knockdown of dPDHB to investigate its role in neuropathy pathogenesis...
February 28, 2018: Experimental Cell Research
Ji Hyoun Kang, Chang Seob Lim, Sung Hwan Park, Sang Woo Seok, Tae Joong Yoon, Badamdorj Bayartogtokh, Yeon Jae Bae
Populations of Gymnopleurus mopsus (family Scarabaeidae), a dung beetle that displays dung-rolling behavior (i.e., a telecoprid), have recently experienced sharp declines, and many populations are now at high risk of local extinction. However, Mongolia, which constitutes a major portion of the species' distribution, still sustains a relatively large population. Here, we used mitochondrial COI sequences to investigate the within-population genetic diversity and both the genetic and phylogeographic structures of 24 G...
March 2, 2018: Scientific Reports
Dung Van Nguyen, Cuong Van Nguyen, David Bonsall, Tue Tri Ngo, Juan Carrique-Mas, Anh Hong Pham, Juliet E Bryant, Guy Thwaites, Stephen Baker, Mark Woolhouse, Peter Simmonds
Rodents and bats are now widely recognised as important sources of zoonotic virus infections in other mammals, including humans. Numerous surveys have expanded our knowledge of diverse viruses in a range of rodent and bat species, including their origins, evolution, and range of hosts. In this study of pegivirus and human hepatitis-related viruses, liver and serum samples from Vietnamese rodents and bats were examined by PCR and sequencing. Nucleic acids homologous to human hepatitis B, C, E viruses were detected in liver samples of 2 (1...
February 28, 2018: Viruses
Dung Phung, Huong Xuan Nguyen, Huong Lien Thi Nguyen, Anh Mai Luong, Cuong Manh Do, Quang Dai Tran, Cordia Chu
OBJECTIVE: To examine the effects of socioecological factors on multiple communicable diseases across Vietnam. METHODS: We used the Moran's I tests to evaluate spatial clusters of diseases and applied multilevel negative binomial regression models using the Bayesian framework to analyse the association between socioecological factors and the diseases queried by oral, airborne, vector-borne, and animal transmission diseases. RESULTS AND SIGNIFICANCE: The study found that oral-transmission diseases were spatially distributed across the country; whereas, the airborne-transmission diseases were more clustered in the Northwest and vector-borne transmission diseases were more clustered in the South...
2018: PloS One
Tran Thanh Binh, Vo Phuoc Tuan, Ho Dang Quy Dung, Pham Huu Tung, Tran Dinh Tri, Ngo Phuong Minh Thuan, Le Quang Tam, Bui Chi Nam, Do Anh Giang, Phan Quoc Hoan, Tomohisa Uchida, Tran Thi Huyen Trang, Vu Van Khien, Yoshio Yamaoka
The Helicobacter pylori -induced burden of gastric cancer varies based on geographical regions and ethnic grouping. Vietnam is a multiethnic country with the highest incidence of gastric cancer in Southeast Asia, but previous studies focused only on the Kinh ethnic group. A population-based cross-sectional study was conducted using 494 volunteers (18-78 years old), from 13 ethnic groups in Daklak and Lao Cai provinces, Vietnam. H. pylori status was determined by multiple tests (rapid urease test, culture, histology, and serology)...
March 1, 2018: International Journal of Molecular Sciences
Takamasa Kinoshita, Kengo Ishiki, Dung Q Nguyen, Hiroshi Shiigi, Tsutomu Nagaoka
Real-time evaluation of bacterial viability is important for various purposes such as hygiene management, development of antibacterial agents, and effective utilization of bacterial resources. Here, we demonstrate a simple procedure for evaluating bacterial viability using gold nanoparticles (Au NPs). The color of bacterial suspensions containing Au NPs strongly depended on the bacterial viability. We found that the dispersion state of Au NPs affected the color of the suspension, based on the interaction of Au NPs with substances secreted by the bacteria...
March 6, 2018: Analytical Chemistry
Kelsey Lee, Khanh-Dung Nguyen, Chao Sun, Mei Liu, Faria Zafar, Jimmy Saetern, Adrian Flierl, James W Tetrud, J William Langston, Dennis Dickson, Birgitt Schüle
BACKGROUND: Mutations in the leucine rich repeat kinase 2 (LRRK2) gene are among the most common genetic causes of Lewy body Parkinson's disease (PD). However, LRRK2 mutations can also lead to a variety of pathological phenotypes other than typical PD, including relatively pure nigrostriatal cell loss without alpha-synuclein-positive Lewy bodies or Lewy neurites, progressive supranuclear palsy (PSP), and multiple system atrophy (MSA). The mechanisms behind this remarkable pleomorphic pathology are currently unclear...
2018: Journal of Parkinson's Disease
Sucharita Patel, Bhatu Kumar Pal, Raj Kishore Patel
In this study, cow dung was identified as a neutralizing agent for red mud (RM). Present research estimated a significant reduction in pH value of red mud (10 g) from 10.28 to 8.15 and reduction in alkalinity of ~148 mg/L from ~488 mg/L by adding 80 g of cow dung in 40 days of anaerobic condition. XRD results exhibit a high intensity of quartz and found new compound, the calcium carbide. The acid neutralizing capacity (ANC) of NRM reduces to ~0.87 from ~1.506 mol H+ /kg. Based on the resultant research, present study proposes cow dung as an efficient neutralizing agent for reducing the pH and alkalinity in the red mud...
February 23, 2018: Environmental Science and Pollution Research International
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"