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contrasted induced nephropathy

James Cain, Jamie Goldstone
No abstract text is available yet for this article.
October 18, 2016: Annals of Internal Medicine
Eric B Bass, Rathan M Subramaniam
No abstract text is available yet for this article.
October 18, 2016: Annals of Internal Medicine
George Lazaros, Theodoros Zografos, Evangelos Oikonomou, Gerasimos Siasos, Georgios Georgiopoulos, Manolis Vavuranakis, Alexios Antonopoulos, Kostas Kalogeras, Sotiris Tsalamandris, Dimitris Tousoulis
Contrast-induced nephropathy (CIN) after percutaneous coronary interventions (PCI) in patients with acute myocardial infarction (AMI) is associated with high morbidity and mortality, whereas there are no reliable predictive tools easy to use. We evaluated the association of pre-procedural high-sensitivity C-reactive protein (hsCRP) with the development of CIN and integrated this variable in a new risk CIN prediction model. Consecutive patients (348 AMI subjects) who underwent PCI were recruited. Creatinine levels were detected on admission, at 24, 48, and 72 hours after PCI...
September 28, 2016: American Journal of Cardiology
Farzanehsadat Minoo, Mahboob Lessan-Pezeshki, Ata Firouzi, Salman Nikfarjam, Seyed Mansoor Gatmiri, Elham Ramezanzade
INTRODUCTION: The aim of the study was to investigate the efficacy of nasal oxygen as a supplementation to hydration therapy in reducing the risk of developing contrast-induced nephropathy (CIN). MATERIALS AND METHODS: In a randomized controlled trial, 348 patients scheduled to undergo elective coronary angiography were randomly allocated to standard hydration plus 2 L/min to 3 L/min nasal oxygen (from 10 minutes before the procedure until the end of the procedure) (n = 176) or standard hydration alone (n = 176)...
September 2016: Iranian Journal of Kidney Diseases
Olimpia Trio, Giuseppe Andò
No abstract text is available yet for this article.
September 30, 2016: International Journal of Cardiology
Maharan Kabha, Snir Dekalo, Sophie Barnes, Ishay Mintz, Haim Matzkin, Mario Sofer
Background: Obstructive nephropathy is an uncommon side effect of sulfadiazine, which is used for the treatment of toxoplasmosis. We present a case of acute renal colic and urine extravasation of a patient shortly after she was started on this medication. Case Presentation: A 31-year-old female presented with acute renal colic 2 weeks after starting treatment with sulfadiazine and pyrimethamine for ocular toxoplasmosis. Results: A noncontrast computed tomography revealed left hydronephrosis and fluid located around the kidney and in the left gutter...
2016: J Endourol Case Rep
Xue-Biao Wei, Lei Jiang, Xin-Rong Liu, Dan-Qing Yu, Ning Tan, Ji-Yan Chen, Ying-Ling Zhou, Peng-Cheng He, Yuan-Hui Liu
PURPOSE: Contrast-induced nephropathy (CIN) is a serious complication and associated with poor clinical outcomes. The protective value of brain natriuretic peptide (BNP) administration on CIN is still controversial in patients undergoing percutaneous coronary intervention (PCI) or coronary angiography (CAG). We performed a meta-analysis of randomized controlled trials (RCTs) for BNP in preventing CIN. METHODS: We systematically searched PubMed, Web of Science, Cochrane Library, and ClinicalTrials...
November 2016: European Journal of Clinical Pharmacology
Renfan Xu, Anyu Tao, Yang Bai, Youbin Deng, Guangzhi Chen
BACKGROUND: Conflicting results have been obtained in trials that have evaluated the prophylactic efficacy of N-acetylcysteine (NAC) pretreatment in the prevention of contrast-induced nephropathy (CIN). In this meta-analysis of randomized controlled trials, we aimed to assess the effectiveness of NAC treatment for the prevention of CIN. METHODS AND RESULTS: PubMed, EMBASE, and the Cochrane Library were electronically searched from inception to January 2016 for all relevant studies...
2016: Journal of the American Heart Association
Lucia Barbieri, Monica Verdoia, Matteo Nardin, Paolo Marino, Harry Suryapranata, Giuseppe De Luca
Contrast-induced nephropathy (CIN) is a common complication of coronary angiography/percutaneous coronary intervention (PCI). Identification of high-risk patients and optimal periprocedural management are key points to reduce the incidence of this iatrogenic complication. We evaluated the impact of gender on CIN after coronary angiography/PCI. We enrolled 2851 consecutive patients (730 females and 1851 males) undergoing coronary angiography/PCI. Baseline clinical and procedural characteristics were collected according to gender...
September 22, 2016: Angiology
Devraj Sukul, Milan Seth, Simon R Dixon, Mark Zainea, Nicklaus K Slocum, Elizabeth J Pielsticker, Hitinder S Gurm
OBJECTIVES: We examined clinical outcomes following percutaneous coronary intervention (PCI) in patients turned down for surgical revascularization across a broad population. BACKGROUND: Prior studies suggest that surgical ineligibility is associated with increased mortality in patients with unprotected left main or multivessel coronary artery disease undergoing PCI. METHODS: This study included consecutive patients who underwent PCI in a multicenter registry in Michigan from January 2010 to December 2014...
September 21, 2016: Catheterization and Cardiovascular Interventions
Mustafa Zungur, Ilker Gul, Ahmet Tastan, Ertan Damar, Talat Tavli
BACKGROUND/AIMS: The Mehran risk score (MS) was adopted to predict the development of contrast-induced nephropathy (CIN) and includes clinical and procedural variables. In this study, we aimed to evaluate the value of MS in the prediction of CIN development after transcatheter aortic valve implantation (TAVI). METHODS: Ninety-three patients (47 females; mean age, 77.2 ± 7.6 years) who underwent aortic valve replacement with TAVI for severe aortic stenosis in our center between June 2013 and November 2014 were included in the study...
August 2016: Cardiorenal Medicine
Ting-Min Hsieh, Tzu-Hsien Tsai, Yueh-Wei Liu, Ching-Hua Hsieh
BACKGROUND: Although angioembolization increases the success rate of non-operative management in patients with blunt splenic injuries (BSI), the issue of contrast-induced nephropathy (CIN) due to serial administration of contrast medium remains unclear. We aimed to examine the risk factors of CIN and their clinical effect on mortality in patients with BSI. METHOD: We retrospectively studied the complete data on 377 trauma patients with BSI who survived more than 48 h between July 2003 and June 2015...
September 10, 2016: International Journal of Surgery
Gungor Sitar, Mehmet Kucuk, Mustafa Erinc Sitar, Ozgur Yasar, Seval Aydin, Karolin Yanar, Ufuk Cakatay, Nur Buyukpınarbasili
BACKGROUND: One of the most important side effects of contrast pharmaceutical agents, which are used very common in routine radiology practice, is contrast induced nephropathy. Even ischemia, oxidative stress and osmolality related cytotoxic effects are considered, the molecular mechanisms underlying this pathology have not been identified completely yet. OBJECTIVES: The aim of the current study was to reveal the role of oxidative stress and antioxidant enzymatic defence mechanisms in the aetiopathogenesis of contrast-induced nephropathy...
June 2016: Iranian Red Crescent Medical Journal
Yuya Adachi, Akihiro Endo, Ryuma Nakashima, Takashi Sugamori, Nobuyuki Takahashi, Yoshihisa Kinoshita, Kazuaki Tanabe
A 76-year-old woman was hospitalized repeatedly due to unexplained heart failure. On admission, she had hypertensive acute heart failure. Her symptoms disappeared promptly after the initial treatment; however, her systolic blood pressure remained at over 160 mmHg despite her taking three antihypertensive drugs. Closer examination revealed hemodynamically significant right renal artery stenosis and a lack of left kidney function. We performed percutaneous transluminal renal angioplasty using CO2 angiography in combination with iodinated contrast agents...
2016: Internal Medicine
Zhimin Liu, Lei Song, Tong Yu, Jun Gao, Qifeng Zhang, Ling Jiang, Yong Liu, Yun Peng
OBJECTIVE: The aim of this study was to explore the feasibility of using low dose radiation and low concentration contrast media in enhanced CT examinations in children with congenital heart disease. MATERIALS AND METHODS: Ninety patients with congenital heart disease were randomly divided into three groups of 30 patients each who underwent contrast-enhanced cardiac scans on a Discovery CT750 HD scanner. Group A received 270 mg I/mL iodixanol, and group B received 320 mg I/mL iodixanol contrast media and was scanned with prospective ECG triggering mode...
September 2016: International Journal of Clinical Practice
Marjolein Garsen, Angelique L W M M Rops, Henry Dijkman, Brigith Willemsen, Toin H van Kuppevelt, Frans G Russel, Ton J Rabelink, Jo H M Berden, Thomas Reinheckel, Johan van der Vlag
Proteinuria is one of the first clinical signs of diabetic nephropathy and an independent predictor for the progression to renal failure. Cathepsin L, a lysosomal cysteine protease, can be involved in the development of proteinuria by degradation of proteins that are important for normal podocyte architecture, such as the CD2-associated protein, synaptopodin, and dynamin. Cathepsin L also activates heparanase, a heparan sulfate endoglycosidase previously shown to be crucial for the development of diabetic nephropathy...
November 2016: Kidney International
Arezoo Khosravi, Mitra Dolatkhah, Hesam Sadat Hashemi, Zohreh Rostami
BACKGROUND: Contrast-induced nephropathy (CIN) is one of the most important complications of angiography in patients with chronic kidney disease (CKD) or diabetes mellitus. The prevention of CIN can decrease therapeutic costs and hospital stays. There is controversy in the literature over the preventive effect of statins on CIN. OBJECTIVES: This study was designed to evaluate the preventive effect of atorvastatin on CIN after angiography in CKD and diabetic patients...
May 2016: Nephro-urology Monthly
G T C Wong, E Y P Lee, M G Irwin
Contrast induced nephropathy (CIN) is traditionally associated with outpatient imaging studies. More recently, patients afflicted with vascular pathologies are increasingly undergoing endovascular treatments that require the use of iodinated contrast media (CM) agents, thus placing them as risk of developing CIN. As perioperative physicians, anaesthetists should be aware of the risk factors and measures that might minimize acute kidney injury caused by CM. This review evaluates recent data regarding preventive measures against CIN and where possible, places the evidence in the context of the patient receiving endovascular surgical treatment...
September 2016: British Journal of Anaesthesia
Joana B Goic, Amy M Koenigshof, Lindsey D McGuire, Anthony C Klinger, Matthew W Beal
OBJECTIVE: To evaluate a population of dogs for evidence of contrast-induced nephropathy (CIN). DESIGN: A retrospective case review between 2006 and 2012. SETTING: A university teaching hospital. ANIMALS: A total of 1,217 client-owned dogs that were administered intravenous iodinated contrast agents were reviewed for evidence of CIN. Inclusion required a measured serum creatinine within 1 week prior as well as within 1 week following administration of contrast...
September 2016: Journal of Veterinary Emergency and Critical Care
Mian Wang, Li Zhang, Rongzheng Yue, Guiying You, Rui Zeng
BACKGROUND Contrast-induced nephropathy is acute kidney injury caused by contrast medium exposure. Serum creatinine is the clinical diagnostic standard, but it does not yield quick results. The serum level of cystatin C is stable and it can reflect renal function sensitively. The study aimed to assess the usefulness of cystatin C for early diagnosis of contrast-induced nephropathy in patients undergoing coronary angiography. MATERIAL AND METHODS We included 300 patients who underwent CAG. According to the sCr at 48 h, patients were divided into 2 groups: CIN group and non-CIN group...
2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
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