Read by QxMD icon Read

pm 2.5

Chris E Freye, Robert E Synovec
A high temperature diaphragm valve-based two-dimensional (2D) gas chromatography (GC×GC) with time-of-flight mass spectrometry (TOFMS) instrument, with the valve mounted directly in the GC oven, is demonstrated with separations up to 325°C. Use of the diaphragm valve allowed for the use of uncoupled carrier gas flows for (1)D (first column dimension) and (2)D (second column dimension), with a (1)D flow rate of 1ml/min, and a (2)D flow rate 3ml/min. The 3ml/min flow rate on (2)D was selected to ensure compatibility with most TOFMS detectors...
December 1, 2016: Talanta
Rebecca DeVries, David Kriebel, Susan Sama
BACKGROUND: Exacerbations of chronic obstructive pulmonary disease (COPD) contribute greatly to increased morbidity, mortality and diminished quality of life. Recent studies report moderately strong positive associations between exposures to several air pollutants and COPD-related emergency department (ED) visits and hospital admissions (HA). Studies that use clinically defined exacerbations rather than counting ED visits and HA may be more sensitive to environmental triggers like air pollution, but very few such studies exist...
October 18, 2016: Environmental Health: a Global Access Science Source
Tetsuo Yamaguchi, Takamichi Miyamoto, Takamasa Iwai, Junji Yamaguchi, Sadahiro Hijikata, Ryoichi Miyazaki, Naoyuki Miwa, Masahiro Sekigawa, Nobuhiro Hara, Yasutoshi Nagata, Toshihiro Nozato, Yasuteru Yamauchi, Toru Obayashi, Mitsuaki Isobe
BACKGROUND: The prognosis of super-elderly patients (age≥85 years) who undergo bradycardia pacemaker (PM) implantation remains unknown. METHODS: We retrospectively enrolled 868 patients (men 49.0%, 76.6±10.6 years) who could walk unassisted and whose expected life expectancy was more than 1 year, receiving their first bradycardia PM implantation between January 1, 2006, and June 30, 2013. Clinical outcomes were compared between super-elderly patients (n=201, mean age 88...
October 15, 2016: Journal of Cardiology
Narathorn Suwanvesh, Jittima Manonai, Areepan Sophonsritsuk, Wichai Cherdshewasart
OBJECTIVES: To compare the effects of a 12-week treatment with Pueraria mirifica (PM) gel or a conjugated estrogen cream on vaginal maturation index, vaginal symptom score, vaginal health assessment score, and vaginal flora in postmenopausal women. METHODS: In a prospective, noninferiority, randomized controlled study, 82 postmenopausal women with at least one vulvovaginal symptom, that is, dryness, soreness, irritation, dyspareunia, or discharge, were recruited...
October 3, 2016: Menopause: the Journal of the North American Menopause Society
Ken G Andersson, Maryam Oroujeni, Javad Garousi, Bogdan Mitran, Stefan Ståhl, Anna Orlova, John Löfblom, Vladimir Tolmachev
The epidermal growth factor receptor (EGFR) is overexpressed in a number of malignant tumors and is a molecular target for several specific anticancer antibodies and tyrosine kinase inhibitors. The overexpression of EGFR is a predictive biomarker for response to several therapy regimens. Radionuclide molecular imaging might enable detection of EGFR overexpression by a non-invasive procedure and could be used repeatedly. Affibody molecules are engineered scaffold proteins, which could be selected to have a high affinity and selectivity to predetermined targets...
October 5, 2016: International Journal of Oncology
Qian Yin, Jinfeng Wang, Maogui Hu, Hoting Wong
When investigating the impact of air pollution on health, particulate matter less than 2.5 μm in aerodynamic diameter (PM2.5) is considered more harmful than particulates of other sizes. Therefore, studies of PM2.5 have attracted more attention. Beijing, the capital of China, is notorious for its serious air pollution problem, an issue which has been of great concern to the residents, government, and related institutes for decades. However, in China, significantly less time has been devoted to observing PM2...
October 2016: Journal of Environmental Sciences (China)
Karen Vrijens, Ellen Winckelmans, Maria Tsamou, Willy Baeyens, Patrick De Boever, Danyel Jennen, Theo M de Kok, Elly Den Hond, Wouter Lefebvre, Michelle Plusquin, Hans Reynders, Greet Schoeters, Nicolas Van Larebeke, Charlotte Vanpoucke, Jos Kleinjans, Tim S Nawrot
BACKGROUND: Particulate matter (PM) exposure leads to premature death, mainly due to respiratory and cardiovascular diseases. OBJECTIVES: Identification of transcriptomic biomarkers of air pollution exposure and effect in a healthy adult population. METHODS: Microarray analyses were performed in 98 healthy volunteers (48 men, 50 women). The expression of 8 sex-specific candidate biomarker genes (significantly associated with PM10 in the discovery cohort and with a reported link to air pollution-related disease) was measured with qPCR in an independent validation cohort (75 men, 94 women)...
October 14, 2016: Environmental Health Perspectives
Min Liu, Wei Fang, Shuang Liu
In this study, we evaluated seven new 99mTc(III) complexes [99mTcCl(CDO)(CDOH)2B-R] (99mTc-2Fboroxime: R = 2-formylfuran-3-yl (2F); 99mTc-3Fboroxime: R = furan-3-yl (3F); 99mTc-5Fboroxime: R = 5-formyfuran-2-yl (5F); 99mTc-HPboroxime: R = 6-hydroxylpyridin-2-yl (HP); 99mTc-MPYboroxime: R = 5-methoxypyridin-3-yl (MPY); 99mTc-PMboroxime: R = 1,5-pyrimidin-3-yl (PM), and 99mTc-4PYboroxime: R = pyridin-4-yl (4PY)) for their potential as heart imaging agents. All new 99mTc(III) radiotracers except 99mTc-2Fboroxime were prepared with high radiochemical purity (RCP > 95%)...
October 13, 2016: Bioconjugate Chemistry
Yan-Su Chen, Fei Meng, Hai-Long Li, Qing-Hua Liu, Ping-Fu Hou, Jin Bai, Jun-Nian Zheng
Dicer, a key component of the microRNA processing machinery, has been reported to exert discrepant prognostic values and biological roles in different types of cancers. Here, we investigated the function and prognostic value of Dicer in clear cell renal cell carcinoma (ccRCC). Using the retrospective ccRCC patients' cohorts with tissue microarray (TMA), we demonstrated that Dicer expression was significantly down-regulated in ccRCC compared with renal non-tumor tissues, and negatively associated with pN status (P = 0...
October 8, 2016: Oncotarget
Lorenzo Loffredo, Roberto Cangemi, Ludovica Perri, Elisa Catasca, Camilla Calvieri, Roberto Carnevale, Cristina Nocella, Francesco Equitani, Domenico Ferro, Francesco Violi, Simona Battaglia, Giuliano Bertazzoni, Elisa Biliotti, Tommaso Bucci, Cinzia Myriam Calabrese, Marco Casciaro, Andrea Celestini, Maurizio De Angelis, Paolo De Marzio, Rozenn Esvan, Marco Falcone, Lucia Fazi, Lucia Fontanelli Sulekova, Cristiana Franchi, Laura Giordo, Stefania Grieco, Elisa Manzini, Paolo Marinelli, Michela Mordenti, Sergio Morelli, Paolo Palange, Daniele Pastori, Pasquale Pignatelli, Marco Rivano Capparuccia, Giulio Francesco Romiti, Elisabetta Rossi, Eleonora Ruscio, Alessandro Russo, Maria Gabriella Scarpellini, Luisa Solimando, Gloria Taliani, Stefano Trapè, Filippo Toriello
BACKGROUND: Community-acquired pneumonia (CAP) is complicated by cardiovascular events as myocardial infarction and stroke but the underlying mechanism is still unclear. We hypothesized that endothelial dysfunction may be implicated and that endotoxemia may have a role. METHODS: Fifty patients with CAP and 50 controls were enrolled. At admission and at discharge, flow-mediated dilation (FMD), serum levels of endotoxins and oxidative stress, as assessed by serum levels of nitrite/nitrate (NOx) and isoprostanes, were studied...
October 7, 2016: European Journal of Internal Medicine
Jaiprakash, Amrita Singhai, Gazala Habib, Ramya Sunder Raman, Tarun Gupta
Fine aerosol fraction (particulate matter with aerodynamic diameter <= 1.0 μm (PM)1.0) over the Indian Institute of Technology Delhi campus was monitored day and night (10 h each) at 30 m height from November 2009 to March 2010. The samples were analyzed for 5 ions (NH4(+), NO3(-), SO4(2-), F(-), and Cl(-)) and 12 trace elements (Na, K, Mg, Ca, Pb, Zn, Fe, Mn, Cu, Cd, Cr, and Ni). Importantly, secondary aerosol (sulfate and nitrate) formation was observed during dense foggy events, supporting the fog-smog-fog cycle...
October 10, 2016: Environmental Science and Pollution Research International
Chia-Chun Tseng, Shun-Jen Chang, Wen-Chan Tsai, Tsan-Teng Ou, Cheng-Chin Wu, Wan-Yu Sung, Ming-Chia Hsieh, Jeng-Hsien Yen
OBJECTIVE: Past studies have shown common pathologic characteristics and shared immunologic features between polymyositis (PM) and amyotrophic lateral sclerosis (ALS). To explore the potential relationship between the two diseases, we performed a nationwide cohort study. METHODS: We identified all newly diagnosed PM from Taiwan's Registry of Catastrophic Illness Database between January 1, 1998 and December 31, 2011. Each PM patient was matched to at most 5 control patients from the National Health Insurance Research Database by sex, age, and entry date...
October 9, 2016: Arthritis Care & Research
Geun-Hye Yu, Seungshik Park, Kwon-Ho Lee
In this study, 24 h size-segregated particulate matter (PM) samples were collected between September 2012 and August 2013 at an urban site in Korea to investigate seasonal mass size distributions of PM and its water-soluble components as well as to infer the possible sources of size-resolved water-soluble organic carbon (WSOC) using a positive matrix factorization (PMF) model. The potential source contribution function (PSCF) was also computed to identify the possible source regions of size-resolved WSOC. The seasonal average contribution of water-soluble organic matter to PM1...
October 12, 2016: Environmental Science. Processes & Impacts
Carlo Fornaini, Elisabetta Merigo, Michele Sozzi, Jean-Paul Rocca, Federica Poli, Stefano Selleri, Annamaria Cucinotta
Objectives: The introduction of diode lasers in dentistry had several advantages, principally consisting on the reduced size, reduced cost and possibility to beam delivering by optical fibbers. Up today only the wavelengths around 810 and 980 nm were the most utilized in oral surgery but recently more different lasers had been proposed. The aim of this study was to compare the efficacy of four diode laser wavelengths (810, 980, 1470 and 1950 nm) for the ablation of soft tissues. Material and methods: Specimens were surgically collected from the dorsal surface of four bovine tongues and irradiated by four different diode wavelengths...
June 29, 2016: Laser Therapy
Kevin K Ariën, Françoise Baleux, Delphine Desjardins, Françoise Porrot, Yves-Marie Coïc, Johan Michiels, Kawthar Bouchemal, David Bonnaffé, Timothée Bruel, Olivier Schwartz, Roger Le Grand, Guido Vanham, Nathalie Dereuddre-Bosquet, Hugues Lortat-Jacob
The CD4 and the cryptic coreceptor binding sites of the HIV-1 envelope glycoprotein are key to viral attachment and entry. We developed new molecules comprising a CD4 mimetic peptide linked to anionic compounds (mCD4.1-HS12 and mCD4.1-PS1), that block the CD4-gp120 interaction and simultaneously induce the exposure of the cryptic coreceptor binding site, rendering it accessible to HS12- or PS1- mediated inhibition. Using a cynomolgus macaque model of vaginal challenge with SHIV162P3, we report that mCD4.1-PS1, formulated into a hydroxyethyl-cellulose gel provides 83% protection (5/6 animals)...
October 10, 2016: Scientific Reports
Laurent Obert, Christelle Peyron, Etienne Boyer, Gauthier Menu, François Loisel, Sébastien Aubry
INTRODUCTION: The shoulder arthroplasty brings satisfaction to patients in terms of quality of life and indolence. However whether anatomic implant or reverse, it does not escape from the loosening of the glenoid component. Moreover, optimal implantation is required to ensure the functional outcome without shortening of the arm. The purpose of this study is obtain CT scan evaluation of the glenoid bone stock in order to optimize glenoid component implantation and obtain a reference to determine optimal humeral component placement in case of humeral proximal fracture...
2016: SICOT-J
Ya-Ru Yang, Yung-Ming Chen, Szu-Ying Chen, Chang-Chuan Chan
BACKGROUND: This study aimed to investigate the associations between particulate matter (PM) exposures and renal function among adults. METHODS: We recruited 21,656 adults as subjects from 2007-2009. The Taiwanese Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation was used to derive the estimated glomerular filtration rate (eGFR). Subjects with an eGFR lower than 60 mL/min/1.73 m(2) were defined as having chronic kidney disease (CKD). Land use regression (LUR) models were used to estimate individual exposures to PM with an aerodynamic diameter <10 μm (PM10), coarse particles (PMCoarse), fine particles (PM2...
October 7, 2016: Environmental Health Perspectives
Alexander L Vogel, Johannes Schneider, Christina Müller-Tautges, Thomas Klimach, Thorsten Hoffmann
Atmospheric oxidation of volatile organic compounds (VOCs) yields a large number of different organic molecules which comprise a wide range of volatility. Depending on their volatility, they can be involved in new particle formation and particle growth, thus affecting the number concentration of cloud condensation nuclei in the atmosphere. Here, we identified oxidation products of VOCs in the particle phase during a field study at a rural mountaintop station in central Germany. We used atmospheric pressure chemical ionization mass spectrometry ((-)APCI-MS) and aerosol mass spectrometry for time-resolved measurements of organic species and of the total organic aerosol (OA) mass in the size range of 0...
October 6, 2016: Environmental Science & Technology
S A H Shah, S M H Andrabi, I Z Qureshi
Effects of curcumin as antioxidant in extender were evaluated on freezability of buffalo spermatozoa. Semen from each of the five bulls (n = 3 replicates, six ejaculates/bull, a total of 30 ejaculates) was diluted in Tris-citric acid extender containing curcumin (0.5, 1.0, 1.5 or 2.0 mM) or control. At pre-freezing and post-thawing, total antioxidant contents (μM/L) and lipid peroxidation levels (μM/ml) were higher (p < .05) and lower (p < .05) respectively, with 1.5 and 2.0 mM compared to 0...
October 6, 2016: Andrologia
Jiyoung Kim, Soo-Jin Cho, Won-Joo Kim, Kwang Ik Yang, Chang-Ho Yun, Min Kyung Chu
BACKGROUND: Insomnia is a common complaint among individuals with migraine. The close association between insomnia and migraine has been reported in clinic-based and population-based studies. Probable migraine (PM) is a migrainous headache which fulfills all but one criterion in the migraine diagnostic criteria. However, an association between insomnia and PM has rarely been reported. This study is to investigate the association between insomnia and PM in comparison with migraine using data from the Korean Headache-Sleep Study...
December 2016: Journal of Headache and Pain
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"