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https://www.readbyqxmd.com/read/27914859/fine-and-ultrafine-atmospheric-particulate-matter-at-a-multi-influenced-urban-site-physicochemical-characterization-mutagenicity-and-cytotoxicity
#1
Yann Landkocz, Frédéric Ledoux, Véronique André, Fabrice Cazier, Paul Genevray, Dorothée Dewaele, Perrine J Martin, Capucine Lepers, Anthony Verdin, Lucie Courcot, Saâd Boushina, François Sichel, Maurizio Gualtieri, Pirouz Shirali, Dominique Courcot, Sylvain Billet
Particulate Matter (PM) air pollution is one of the major concerns for environment and health. Understanding the heterogeneity and complexity of fine and ultrafine PM is a fundamental issue notably for the assessment of PM toxicological effects. The aim of this study was to evaluate mutagenicity and cytotoxicity of a multi-influenced urban site PM, with or without the ultrafine fraction. For this purpose, PM2.5-0.3 (PM with aerodynamic diameter ranging from 0.3 to 2.5 μm) and PM2.5 were collected in Dunkerque, a French coastal industrial city and were extensively characterized for their physico-chemical properties, including inorganic and organic species...
November 30, 2016: Environmental Pollution
https://www.readbyqxmd.com/read/27914144/outdoor-air-pollution-and-pterygium-in-korea
#2
Ki Woong Lee, Yoon Hyeong Choi, Sung Ha Hwang, Hae Jung Paik, Mee Kum Kim, Won Ryang Wee, Dong Hyun Kim
We investigated relationships between outdoor air pollution and pterygium in Korean adults. This study includes 23,276 adults in population-based cross-sectional data using the Korea National Health and Nutrition Examination Survey 2008-2011. Pterygium was assessed using slit lamp biomicroscopy. Air pollution data (humidity, particulate matter with aerodynamic diameter less than 10 μm [PM₁₀], ozone [O₃], nitrogen dioxide [NO₂], and sulfur dioxide levels [SO₂]) for 2 years preceding the ocular examinations were acquired...
January 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/27913214/alk-rearranged-non-small-cell-lung-cancer-is-associated-with-a-high-rate-of-venous-thromboembolism
#3
Alona Zer, Mor Moskovitz, David M Hwang, Anat Hershko-Klement, Ludmila Fridel, Grzegorz J Korpanty, Elizabeth Dudnik, Nir Peled, Tzippy Shochat, Natasha B Leighl, Geoffrey Liu, Ronald Feld, Ronald Burkes, Mira Wollner, Ming-Sound Tsao, Frances A Shepherd
BACKGROUND: Patients with lung cancer are at increased risk for venous thromboembolism (VTE), particularly those receiving chemotherapy. It is estimated that 8% to 15% of patients with advanced non-small-cell lung cancer (NSCLC) experience a VTE in the course of their disease. The incidence in patients with specific molecular subtypes of NSCLC is unknown. We undertook this review to determine the incidence of VTE in patients with ALK (anaplastic lymphoma kinase)-rearranged NSCLC. PATIENTS AND METHODS: We identified all patients with ALK-rearranged NSCLC diagnosed and/or treated at the Princess Margaret Cancer Centre (PM CC) in Canada between July 2012 and January 2015...
October 26, 2016: Clinical Lung Cancer
https://www.readbyqxmd.com/read/27911466/transparent-nanofibrous-mesh-self-assembled-from-molecular-legos-for-high-efficiency-air-filtration-with-new-functionalities
#4
Varun Kumar Singh, Sai Kishore Ravi, Wanxin Sun, Swee Ching Tan
Alarming levels of particulate matter pollution in air pose a serious health threat in several countries, therefore intriguing a strong need for an economic and a viable technology of air filtration. Current air purification technology is rather expensive with certain types even having the risk of emitting hazardous by-products. The authors have developed a multifunctional air filter inspired from the nasal hairs possessing an ability to specifically trap/exhale the foreign particles and allergens while still letting the air flow...
December 2, 2016: Small
https://www.readbyqxmd.com/read/27906312/widely-tunable-narrow-linewidth-external-cavity-gain-chip-laser-for-spectroscopy-between-1-0-1-1-%C3%A2%C2%B5m
#5
Dong K Shin, Bryce M Henson, Roman I Khakimov, Jacob A Ross, Colin J Dedman, Sean S Hodgman, Kenneth G H Baldwin, Andrew G Truscott
We have developed and characterised a stable, narrow linewidth external-cavity laser (ECL) tunable over 100 nm around 1080 nm, using a single-angled-facet gain chip. We propose the ECL as a low-cost, high-performance alternative to fibre and diode lasers in this wavelength range and demonstrate its capability through the spectroscopy of metastable helium. Within the coarse tuning range, the wavelength can be continuously tuned over 30 pm (7.8 GHz) without mode-hopping and modulated with bandwidths up to 3 kHz (piezo) and 37(3) kHz (current)...
November 28, 2016: Optics Express
https://www.readbyqxmd.com/read/27906031/contrasting-biological-potency-of-particulate-matter-collected-at-sites-impacted-by-distinct-industrial-sources
#6
Errol M Thomson, Dalibor Breznan, Subramanian Karthikeyan, Christine MacKinnon-Roy, Ngoc Q Vuong, Ewa Dabek-Zlotorzynska, Valbona Celo, Jean-Pierre Charland, Prem Kumarathasan, Jeffrey R Brook, Renaud Vincent
BACKGROUND: Industrial sources contribute a significant proportion of anthropogenic particulate matter (PM) emissions, producing particles of varying composition that may differentially impact health. This study investigated the in vitro toxicity of ambient PM collected near industrial sites in relation to particle size and composition. METHODS: Size-fractionated particles (ultrafine, PM0.1-2.5, PM2.5-10, PM>10) were collected in the vicinity of steel, copper, aluminium, and petrochemical industrial sites...
December 1, 2016: Particle and Fibre Toxicology
https://www.readbyqxmd.com/read/27901526/direct-conjugation-of-antibodies-to-the-zns-shell-of-quantum-dots-for-fret-immunoassays-with-low-picomolar-detection-limits
#7
S Bhuckory, L Mattera, K D Wegner, X Qiu, Y-T Wu, L J Charbonnière, P Reiss, N Hildebrandt
Compact and functional nanoparticle-antibody conjugates are of paramount importance for the development of quantum dot (QD)-based immunoassays. Here, we present a simple strategy to directly conjugate IgG, F(ab')2, and Fab antibodies via their endogenous disulfide groups directly to the inorganic ZnS shell of compact penicillamine-coated QDs. The functionality of the conjugates was demonstrated by terbium (Tb)-to-QD FRET immunoassays against prostate specific antigen in serum samples. Detection limits of 2...
November 30, 2016: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/27900624/the-sources-of-trace-element-pollution-of-dry-depositions-nearby-a-drinking-water-source
#8
Xinyue Guo, Hongbing Ji, Cai Li, Yang Gao, Huaijian Ding, Lei Tang, Jinguo Feng
Miyun Reservoir is one of the most important drinking water sources for Beijing. Thirteen atmospheric PM sampling sites were established around this reservoir to analyze the mineral composition, morphological characteristics, element concentration, and sources of atmospheric PM pollution, using transmission electron microscope, X-ray diffraction, and inductively coupled plasma mass spectrometry analyses. The average monthly dry deposition flux of aerosols was 15.18 g/m(2), with a range of 5.78-47.56 g/m(2)...
November 29, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27898909/protein-and-amino-acid-bioavailability-of-extruded-dog-food-with-protein-meals-of-different-quality-using-growing-mink-as-a-model
#9
M T Tjernsbekk, A-H Tauson, C F Matthiesen, Ø Ahlstrøm
The present study evaluated growing mink () as a model for dietary protein quality assessment of protein meals used in extruded dog foods. Three foods with similar CP content but of different protein quality were produced using different protein meals. The protein meals varied with respect to CP digestibility and AA composition and included lamb meal (LBM), poultry meal (PM), and fish meal (FM) with low, intermediate, and high protein quality, respectively. Nitrogen balance, BW gain, protein efficiency ratio (PER), and apparent total tract digestibility (ATTD) were used as measures of protein and AA bioavailability in growing mink...
September 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/27896403/histology-is-a-prognostic-indicator-after-pulmonary-metastasectomy-from-renal-cell-carcinoma
#10
Yoichi Ohtaki, Kimihiro Shimizu, Keiju Aokage, Masayuki Nakao, Junji Yoshida, Mitsuhiro Kamiyoshihara, Masayuki Sugano, Yusuke Takahashi, Seshiru Nakazawa, Toshiteru Nagashima, Kai Obayashi, Tomoyuki Hishida, Masahiro Tsuboi, Shohei Mori, Mingyon Mun, Sakae Okumura, Hitoshi Igai, Noriyuki Matsutani, Akira Mogi, Hiroyuki Kuwano
OBJECTIVES: There are only a few detailed reports concerning the prognosticators following surgical resection of pulmonary metastases (PMs) from renal cell carcinoma (RCC). We investigated the prognosis of patients with RCC PMs undergoing pulmonary metastasectomy and identified prognostic factors in a multi-institutional retrospective study. METHODS: We retrospectively evaluated 84 patients who underwent resection of PMs from RCC between 1993 and 2014. We assessed the clinicopathological characteristics, focusing on the histological findings of PMs...
November 28, 2016: World Journal of Surgery
https://www.readbyqxmd.com/read/27894310/monitoring-change-in-volume-of-calcifications-in-juvenile-idiopathic-inflammatory-myopathy-a-pilot-study-using-low-dose-computed-tomography
#11
Maria Ibarra, Cynthia Rigsby, Gabrielle A Morgan, Christina L Sammet, Chiang-Ching Huang, Dong Xu, Ira N Targoff, Lauren M Pachman
BACKGROUND: Dystrophic calcifications may occur in patients with J uvenile Idiopathic Inflammatory Myopathy (JIIM) as well as other connective tissue and metabolic diseases, but a reliable method of measuring the volume of these calcifications has not been established. The purpose of this study is to determine the feasibility of low dose, limited slice, Computed Tomography (CT) to measure objectively in-situ calcification volumes in patients with JIIM over time. METHODS: Ten JIIM patients (eight JDM, two Overlap) with calcifications were prospectively recruited over a 2-year period to undergo two limited, low dose, four-slice CT scans...
November 29, 2016: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/27892410/short-term-no2-exposure-is-associated-with-long-chain-fatty-acids-in-prospective-cohorts-from-augsburg-germany-results-from-an-analysis-of-138-metabolites-and-three-exposures
#12
Cavin K Ward-Caviness, Susanne Breitner, Kathrin Wolf, Josef Cyrys, Gabi Kastenmüller, Rui Wang-Sattler, Alexandra Schneider, Annette Peters
BACKGROUND: Short-term exposure to air pollution is associated with morbidity and mortality. Metabolites are intermediaries in biochemical processes, and associations between air pollution and metabolites can yield unique mechanistic insights. METHODS: We used independent cross-sectional samples with targeted metabolomics (138 metabolites across five metabolite classes) from three cohort studies, each a part of the Cooperative Health Research in the Region of Augsburg (KORA)...
October 2016: International Journal of Epidemiology
https://www.readbyqxmd.com/read/27887857/a-potential-contribution-of-dipeptidyl-peptidase-4-by-the-mediation-of-monocyte-differentiation-in-the-development-and-progression-of-abdominal-aortic-aneurysms
#13
Hsin-Ying Lu, Chun-Yao Huang, Chun-Ming Shih, Yi-Wen Lin, Chein-Sung Tsai, Feng-Yen Lin, Chun-Che Shih
OBJECTIVE: Abdominal aortic aneurysms (AAAs) are characterized by the destruction of elastin and collagen in the media and adventitia. Dipeptidyl peptidase-4 (DPP-4, an adipokine known as CD26) influences cell signaling, cell-matrix interactions, and the regulation of the functional activity of incretins in metabolic and inflammatory disorders. Although the role of DPP-4 in AAA evolution has been demonstrated, the underlying mechanisms of DPP-4-regulated AAA development remains unknown...
November 22, 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/27884469/chinese-province-scale-source-apportionments-for-sulfate-aerosol-in-2005-evaluated-by-the-tagged-tracer-method
#14
Syuichi Itahashi, Hiroshi Hayami, Keiya Yumimoto, Itsushi Uno
Appropriate policies to improve air quality by reducing anthropogenic emissions are urgently needed. This is typified by the particulate matter (PM) problem and it is well known that one type of PM, sulfate aerosol (SO4(2-)), has a large-scale impact due to long range transport. In this study we evaluate the source-receptor relationships of SO4(2-) over East Asia for 2005, when anthropogenic sulfur dioxide (SO2) emissions from China peaked. SO2 emissions from China have been declining since 2005-2006, so the possible maximum impact of Chinese contributions of SO4(2-) is evaluated...
November 22, 2016: Environmental Pollution
https://www.readbyqxmd.com/read/27870974/myocardial-perfusion-in-peripheral-raynaud-s-phenomenon-evaluation-using-stress-cardiovascular-magnetic-resonance
#15
Sophie Mavrogeni, Konstantinos Bratis, Loukia Koutsogeorgopoulou, Georgia Karabela, Efthymios Savropoulos, Gikas Katsifis, John Raftakis, George Markousis-Mavrogenis, Genovefa Kolovou
BACKGROUND: Peripheral Raynaud's phenomenon (RP) is either primary (PRP), without any coexisting disease or secondary (SRP), due to connective tissue diseases (CTD). We hypothesized that adenosine stress cardiovascular magnetic resonance (CMR) can assess myocardial perfusion in a population of PRP and SRP. PATIENTS-METHODS: Twenty CTDs, aged 30.6±7.5yrs., 16F/4M, including 9 systemic sclerosis (SSc), 4 systemic lupus erythematosus (SLE), 3 mixed connective tissue disease (MCTD), 2 polymyositis (PM) and 2 rheumatoid arthritis (RA), with SRP, under treatment with calcium blockers, were evaluated by stress CMR and compared with age-sex matched PRP and controls...
November 12, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27855223/particulate-matter-2-5-exposure-and-self-reported-use-of-wood-stoves-and-other-indoor-combustion-sources-in-urban-nonsmoking-homes-in-norway
#16
Annah B Wyss, Anna Ciesielski Jones, Anette K Bølling, Grace E Kissling, Ryan Chartier, Hans Jørgen Dahlman, Charles E Rodes, Janet Archer, Jonathan Thornburg, Per E Schwarze, Stephanie J London
Few studies have examined particulate matter (PM) exposure from self-reported use of wood stoves and other indoor combustion sources in urban settings in developed countries. We measured concentrations of indoor PM < 2.5 microns (PM2.5) for one week with the MicroPEM™ nephelometer in 36 households in the greater Oslo, Norway metropolitan area. We examined indoor PM2.5 levels in relation to use of wood stoves and other combustion sources during a 7 day monitoring period using mixed effects linear models with adjustment for ambient PM2...
2016: PloS One
https://www.readbyqxmd.com/read/27847976/size-distribution-of-chlorinated-polycyclic-aromatic-hydrocarbons-in-atmospheric-particles
#17
Kensaku Kakimoto, Haruna Nagayoshi, Yoshimasa Konishi, Keiji Kajimura, Takeshi Ohura, Takeshi Nakano, Mitsuhiko Hata, Masami Furuuchi, Ning Tang, Kazuichi Hayakawa, Akira Toriba
The particle size distribution of chlorinated polycyclic aromatic hydrocarbons (ClPAHs) in particulate matter (PM) in Japan is examined for the first time. PM was collected using a PM0.1 air sampler with a six-stage filter. PM was collected in October 2014 and January 2015 to observe potential seasonal variation in the atmospheric behavior and size of PM, including polycyclic aromatic hydrocarbons (PAHs) and ClPAHs. We found that the concentration of PAHs and ClPAHs between 0.5-1.0 μm and 1.0-2.5 μm markedly increase in January (i...
November 15, 2016: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/27843509/association-between-health-symptoms-and-particulate-matter-from-traffic-and-residential-heating-results-from-rhine-iii-in-tartu
#18
Mihkel Pindus, Hans Orru, Marek Maasikmets, Marko Kaasik, Rain Jõgi
BACKGROUND: Traffic and residential heating are the main sources of particulate matter (PM) in Northern Europe. Wood is widely used for residential heating and vehicle numbers are increasing. Besides traffic exhaust, studded tires produce road dust that is the main source of traffic-related PM10. Several studies have associated total PM mass with health symptoms; however there has been little research on the effects of PM from specific sources. OBJECTIVE: To study the health effects resulting from traffic and local heating PM...
2016: Open Respiratory Medicine Journal
https://www.readbyqxmd.com/read/27843010/identifying-sensitive-windows-for-prenatal-particulate-air-pollution-exposure-and-mitochondrial-dna-content-in-cord-blood
#19
Maria José Rosa, Allan C Just, Marco Sánchez Guerra, Itai Kloog, Hsiao-Hsien Leon Hsu, Kasey J Brennan, Adriana Mercado García, Brent Coull, Rosalind J Wright, Martha María Téllez Rojo, Andrea A Baccarelli, Robert O Wright
INTRODUCTION: Changes in mitochondrial DNA (mtDNA) can serve as a marker of cumulative oxidative stress (OS) due to the mitochondria's unique genome and relative lack of repair systems. In utero particulate matter ≤2.5μm (PM2.5) exposure can enhance oxidative stress. Our objective was to identify sensitive windows to predict mtDNA damage experienced in the prenatal period due to PM2.5 exposure using mtDNA content measured in cord blood. MATERIAL AND METHODS: Women affiliated with the Mexican social security system were recruited during pregnancy in the Programming Research in Obesity, Growth, Environment and Social Stressors (PROGRESS) study...
November 11, 2016: Environment International
https://www.readbyqxmd.com/read/27835752/chemical-components-of-respirable-particulate-matter-associated-with-emergency-hospital-admissions-for-type-2-diabetes-mellitus-in-hong-kong
#20
Shengzhi Sun, Hong Qiu, Kin-Fai Ho, Linwei Tian
BACKGROUND: Epidemiological studies have shown that short-term exposure to particulate matter (PM) mass is associated with diabetes morbidity and mortality, although inconsistencies still exist. Variation of chemical components in PM may have contributed to these inconsistencies. We hypothesize that certain components of respirable particulate matter (PM10), not simply PM10 mass, can exacerbate symptoms or cause acute complications for type 2 diabetes mellitus (T2DM). METHODS: We used a Poisson time-series model to examine the association between 17 chemical components of PM10 and daily emergency hospital admissions for T2DM among residents aged 65years or above from January 1998 to December 2007 in Hong Kong...
October 27, 2016: Environment International
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