keyword
MENU ▼
Read by QxMD icon Read
search

pm 2.5

keyword
https://www.readbyqxmd.com/read/28088011/particulates-and-noise-exposure-during-bicycle-bus-and-car-commuting-a-study-in-three-european-cities
#1
Enembe O Okokon, Tarja Yli-Tuomi, Anu W Turunen, Pekka Taimisto, Arto Pennanen, Ilias Vouitsis, Zissis Samaras, Marita Voogt, Menno Keuken, Timo Lanki
BACKGROUND: In order to curb traffic-related air pollution and its impact on the physical environment, contemporary city commuters are encouraged to shift from private car use to active or public transport modes. However, personal exposures to particulate matter (PM), black carbon and noise during commuting may be substantial. Therefore, studies comparing exposures during recommended modes of transport versus car trips are needed. METHODS: We measured personal exposure to various-sized particulates, soot, and noise during commuting by bicycle, bus and car in three European cities: Helsinki in Finland, Rotterdam in the Netherlands and Thessaloniki in Greece using portable monitoring devices...
January 11, 2017: Environmental Research
https://www.readbyqxmd.com/read/28087836/neuropathological-consequences-of-gestational-exposure-to-concentrated-ambient-fine-and-ultrafine-particles-in-the-mouse
#2
Carolyn Klocke, Joshua L Allen, Marissa Sobolewski, Margot Mayer-Pröschel, Jason L Blum, Dana Lauterstein, Judith T Zelikoff, Deborah A Cory-Slechta
Increasing evidence indicates that the central nervous system (CNS) is a target of air pollution. We previously reported that postnatal exposure of mice to concentrated ambient ultrafine particles (UFP; ≤100nm) via the University of Rochester HUCAPS system during a critical developmental window of CNS development, equivalent to human 3(rd) trimester, produced male-predominant neuropathological and behavioral characteristics common to multiple neurodevelopmental disorders, including autism spectrum disorder (ASD), in humans...
January 13, 2017: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/28087064/effect-of-cyp2d6-polymorphisms-on-the-pharmacokinetics-of-propafenone-and-its-two-main-metabolites
#3
Mohammad-Reza Rouini, Minoo Afshar
AIM OF THE STUDY: Propafenone (PPF) is an antiarrhythmic drug, metabolized mainly by CYP2D6 to 5-hydroxypropafenone (5OH-PPF) and by CYP3A4 to norpropafenone (NOR-PPF). CYP2D6 shows a high degree of genetic polymorphism which is associated with diminished antiarrhythmic efficacy or cardiac seizures/cardiotoxicity. This study aimed to investigate the effect of the CYP2D6 polymorphism on the pharmacokinetics of PPF and its two main metabolites. The usefulness of PPF/5OH-PPF ratio for CYP2D6 phenotyping in healthy adults was also evaluated...
December 19, 2016: Thérapie
https://www.readbyqxmd.com/read/28081088/am-to-pm-conversion-in-a-resonant-microwave-optical-rectification-detector
#4
Brian H Kolner, Lanbing Kang
A LiNbO<sub>3</sub>-loaded microwave cavity pumped with weakly AM-modulated 30 fs optical pulses was used as a platform to investigate AM-to-PM conversion in the optical rectification process. Theoretical treatment of AM-to-PM conversion (i.e., peak-induced electrical phase deviation β<sub>i</sub> due to optical power modulation with index m) suggests that the dominant mechanism is self-group-velocity modulation due to χ<sup>(3)</sup> and cascaded χ<sup>(2)</sup> processes with a value of δ=β<sub>i</sub>/m=-151  dB, linearly dependent on the optical power at intensities of 6×10<sup>10</sup>  W/m<sup>2</sup> in a 40 mm long LiNbO<sub>3</sub> crystal...
January 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28081070/second-harmonic-generation-via-femtosecond-laser-fabrication-of-poled-quasi-phase-matched-waveguides-in-fused-silica
#5
Jason C Ng, Peter R Herman, Li Qian
Second harmonic generation (SHG) is demonstrated in femtosecond laser written waveguides in fused silica through a combination of thermal poling and laser-based quasi-phase-matching (QPM) techniques. Quasi-phase-matching was controlled by the periodic erasure of induced nonlinearity through femtosecond laser erasure. A maximum SHG conversion efficiency of 6.6±0.5×10<sup>-5</sup>%/W is reported for the fundamental wavelength of 1552.8 nm with a phase-matching bandwidth of 4.4 nm for a 10.0 mm long waveguide...
January 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28078629/effect-of-microneedle-type-on-transdermal-permeation-of-rizatriptan
#6
Chandrateja Uppuluri, Ashraf Sultana Shaik, Tao Han, Atul Nayak, Karthik J Nair, Benjamin R Whiteside, Buchi N Nalluri, Diganta B Das
The present study was aimed to investigate the effect of salient microneedle (MN) geometry parameters like length, density, shape and type on transdermal permeation of rizatriptan (RIZ). Studies were carried out using two types of MN devices viz. AdminPatch® arrays (ADM) (0.6, 0.9, 1.2 and 1.5 mm lengths) and laboratory-fabricated polymeric MNs (PMs) of 0.6 mm length. In the case of the PMs, arrays were applied three times at different places within a 1.77-cm(2) skin area (PM-3) to maintain the MN density closer to 0...
January 11, 2017: AAPS PharmSciTech
https://www.readbyqxmd.com/read/28073883/infective-endocarditis-and-risk-of-death-after-cardiac-implantable-electronic-device-implantation-a-nationwide-cohort-study
#7
Cengiz Özcan, Jakob Raunsø, Morten Lamberts, Lars Køber, Tommi Bo Lindhardt, Niels Eske Bruun, Marie Louise Laursen, Christian Torp-Pedersen, Gunnar Hilmar Gislason, Morten Lock Hansen
AIMS: To determine the incidence, risk factors, and mortality of infective endocarditis (IE) following implantation of a first-time, permanent, cardiac implantable electronic device (CIED). METHODS AND RESULTS: From Danish nationwide administrative registers (beginning in 1996), we identified all de-novo permanent pacemakers (PMs) and implantable cardioverter defibrillators (ICDs) together with the occurrence of post-implantation IE-events in the period from 2000-2012...
January 10, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28071057/programmed-transfer-of-sequence-information-into-molecularly-imprinted-polymer-mip-for-hexa-2-2-bithien-5-yl-dna-analog-formation-towards-single-nucleotide-polymorphism-snp-detection
#8
Katarzyna Bartold, Agnieszka Pietrzyk-Le, Tan-Phat Huynh, Zofia Iskierko, Marta I Sosnowska, Krzysztof Noworyta, Wojciech Lisowski, Francesco Maria Enrico Sannicolo, Silvia Cauteruccio, Emanuela Licandro, Francis D'Souza, Wlodzimierz Kutner
A new strategy of simple, inexpensive, rapid, and label-free single nucleotide polymorphism (SNP) detection using robust chemosensors with piezomicrogravimetric (PM), SPR, or capacitive impedimetry (CI) signal transduction is reported. Using these chemosensors, selective detection of a genetically relevant oligonucleotide under FIA conditions within 2 min is accomplished. An invulnerable to non-specific interaction molecularly imprinted polymer (MIP) with electrochemically synthesized probes of hexameric 2,2'-bithien-5-yl DNA analogs discriminating single purine-nucleobase mismatch at room temperature was used...
January 10, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28066851/analysis-of-smartphone-interruptions-on-academic-general-internal-medicine-wards-frequent-interruptions-may-cause-a-crisis-mode-work-climate
#9
Alon Vaisman, Robert C Wu
INTRODUCTION: Hospital-based medical services are increasingly utilizing team-based pagers and smartphones to streamline communications. However, an unintended consequence may be higher volumes of interruptions potentially leading to medical error. There is likely a level at which interruptions are excessive and cause a 'crisis mode' climate. METHODS: We retrospectively collected phone, text messaging, and email interruptions directed to hospital-assigned smartphones on eight General Internal Medicine (GIM) teams at two tertiary care centres in Toronto, Ontario from April 2013 to September 2014...
January 4, 2017: Applied Clinical Informatics
https://www.readbyqxmd.com/read/28065572/uneven-distribution-of-inorganic-pollutants-in-marine-air-originating-from-ocean-going-ships
#10
László Bencs, Benjamin Horemans, Anna Jolanta Buczyńska, René Van Grieken
The distribution of mass, water-soluble inorganic salts and mineral elements of size-segregated aerosols (PM1, PM2.5-1 and PM10-2.5), precursor gaseous pollutants, black carbon, and nanoparticles (10-300 nm size range) at the Southern Bight of the North Sea has been studied. The concentrations of air pollutants peaked over shipping lanes, open-water anchorage areas and frequently navigated waters, due to the presence of mobile emission sources. A considerable decrease in air pollutant levels was seen when diverting from these marine areas towards remote or coastal banks...
January 5, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28061531/effects-of-circadian-rhythms-and-treatment-times-on-the-response-of-radiotherapy-for-painful-bone-metastases
#11
Stephanie Chan, Liying Zhang, Leigha Rowbottom, Rachel McDonald, Georg A Bjarnason, May Tsao, Elizabeth Barnes, Cyril Danjoux, Marko Popovic, Henry Lam, Carlo DeAngelis, Edward Chow
BACKGROUND: Previous studies have observed how the time of radiotherapy delivery can impact toxicities and outcomes. The goal of this study was to determine whether treatment time influenced radiotherapy response for bone metastases. METHODS: Patients who received radiation treatment to painful bone metastases from January 2000 to December 2010 were included in our analysis. Demographic and treatment information including performance status, primary site, treatment dose and fraction, and response were collected prospectively...
October 19, 2016: Annals of Palliative Medicine
https://www.readbyqxmd.com/read/28061370/fine-particulate-air-pollution-and-premature-ventricular-contractions-the-reasons-for-geographic-and-racial-differences-in-stroke-regards-study
#12
Wesley T O'Neal, Elsayed Z Soliman, Jimmy T Efird, Virginia J Howard, George Howard, Leslie A McClure
BACKGROUND: It is unknown if higher levels of ambient particulate matter (PM) exposure increase the risk for premature ventricular contractions (PVC) in a population-based study of men and women, and if this relationship varies by race or sex. METHODS: We examined the association of PM <2.5µm in diameter (PM2.5) concentration with PVCs in 26,121 (mean age=64±9.3 years; 55% female; 41% black) participants from the REasons for Geographic And Racial Differences in Stroke (REGARDS) study...
January 3, 2017: Environmental Research
https://www.readbyqxmd.com/read/28060518/in-use-emissions-and-estimated-impacts-of-traditional-natural-and-forced-draft-cookstoves-in-rural-malawi
#13
Roshan Wathore, Kevin Mortimer, Andrew P Grieshop
Emissions from traditional cooking practices in low- and middle-income countries have detrimental health and climate effects; cleaner-burning cookstoves may provide "co-benefits". Here we assess this potential via in-home measurements of fuel-use and emissions and real-time optical properties of pollutants from traditional and alternative cookstoves in rural Malawi. Alternative cookstove models were distributed by existing initiatives and include a low-cost ceramic model, two forced-draft cookstoves (FDCS; Philips™ HD4012LS and ACE-1), and several institutional cookstoves...
January 6, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28060413/molecularly-imprinted-polymer-chemosensor-for-selective-determination-of-an-n-nitroso-l-proline-food-toxin
#14
Patrycja Lach, Piyush Sindhu Sharma, Karolina Golebiewska, Maciej Cieplak, Francis D'Souza, Wlodzimierz Kutner
A molecularly imprinted polymer (MIP)-based chemosensor for the selective determination of a chosen toxin, N-nitroso-l-proline (Pro-NO), was devised and fabricated. By means of DFT, the structure of the pre-polymerization (functional monomer)-template complex was modeled. This complex was then potentiodynamically electropolymerized in the presence of cross-linking monomer to form a MIP-Pro-NO thin film. Next, the Pro-NO template was extracted from MIP-Pro-NO with 0.1 m NaOH. Piezoelectric microgravimetry (PM) on an electrochemical quartz crystal microbalance and electrochemical (differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy (EIS)) techniques were used to transduce binding of Pro-NO to molecular cavities of the MIP-Pro-NO...
November 7, 2016: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28059355/self-homodyne-24%C3%A3-32-qam-superchannel-receiver-enabled-by-all-optical-comb-regeneration-using-brillouin-amplification
#15
Abel Lorences-Riesgo, Mikael Mazur, Tobias A Eriksson, Peter A Andrekson, Magnus Karlsson
We demonstrate and characterize an all-optical self-homodyne (SH) frequency superchannel enabled by comb regeneration at the receiver. In order to generate the superchannel, we use a frequency comb with 26 carriers spaced by 25 GHz at the transmitter, from which 24 carriers are modulated with polarization-multiplexed 32 quadrature amplitude modulation (PM 32-QAM) data. To enable comb regeneration at the receiver side, the two central carriers remain unmodulated. High fidelity comb regeneration is achieved by filtering the two unmodulated carriers with an approximately 25 MHz wide optical filter based on Brillouin amplification before a parametric mixer...
December 26, 2016: Optics Express
https://www.readbyqxmd.com/read/28057075/the-efficacy-of-prospective-memory-rehabilitation-plus-metacognitive-skills-training-for-adults-with-traumatic-brain-injury-study-protocol-for-a-randomized-controlled-trial
#16
Jennifer Fleming, Tamara Ownsworth, Emmah Doig, Lauren Hutton, Janelle Griffin, Melissa Kendall, David H K Shum
BACKGROUND: Impairment of prospective memory (PM) is common following traumatic brain injury (TBI) and negatively impacts on independent living. Compensatory approaches to PM rehabilitation have been found to minimize the impact of PM impairment in adults with TBI; however, poor self-awareness after TBI poses a major barrier to the generalization of compensatory strategies in daily life. Metacognitive skills training (MST) is a cognitive rehabilitation approach that aims to facilitate the development of self-awareness in adults with TBI...
January 5, 2017: Trials
https://www.readbyqxmd.com/read/28056405/size-segregated-pm-and-its-chemical-composition-emitted-from-heated-corn-oil
#17
Mehdi Amouei Torkmahalleh, Soudabeh Gorjinezhad, Melek Keles, Fatma Ozturk, Philip K Hopke
Characterization of the airborne particulate matter (PM) emitted from cooking components including cooking oil, and additives like salt has not been carefully investigated. This study provides new data on the concentration, composition, and emission rates/fluxes of PM (less than 3.3µm) generated during heating corn oil and corn oil with added table salt. The concept of emission flux was employed to estimate the emission rates in this study. A statistically significant reduction of 47.6% (P<0.05) in the total PM emission rate and emission flux were observed when salt was added to the heated corn oil (5...
January 2, 2017: Environmental Research
https://www.readbyqxmd.com/read/28054445/anti-diabetic-activities-of-cis-and-trans-2-3-5-4-tetrahydroxystilbene-2-o-%C3%AE-glucopyranoside-from-polygonum-multiflorum
#18
Wenping Tang, Shiming Li, Yue Liu, Jia-Ching Wu, Min-Hsiung Pan, Mou-Tuan Huang, Chi-Tang Ho
SCOPE: Functional foods can be used alone or in combination with existing therapies in preventing and treating type 2 diabetes (T2D). Trans-2,3,5,4'-tetrahydroxystilbene 2-O-β-glucopyranoside (trans-THSG), a dominant bioactive compound from Polygonum multiflorum (PM) - a popular medicinal food in Asia, has attracted increasing research interests due to its strong antioxidant activity. The content of naturally occurring cis-THSG (cis-2,3,5,4'-tetrahydroxystilbene 2-O-β-glucopyranoside) was very low in PM root, but was prepared in this research by mimicking the traditional process of PM...
January 5, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28054203/molecular-explorations-of-substituted-2-4-phenylquinolin-2-yl-phenols-as-phosphoinositide-3-kinase-inhibitors-and-anticancer-agents
#19
Manikandan Alagumuthu, Sivakumar Arumugam
PURPOSE: Substituted 2-(4-phenylquinolin-2-yl) phenols (PQPDs) emerged as the inhibitors of phosphoinositide 3-kinase (PI3K) and anticancer agents. METHOD: PI3K inhibition was assessed by competitive ELISA. Anticancer activity was evaluated against breast cancer (MCF-7), skin cancer (G-361), and colon cancer (HCT 116) cell lines. RESULTS: In PI3 Kinase assay, PQPDs 4c, 4d, and 4k were inactive with IC50 >5 µM. IC50 for 4a, 4b, 4f-h, and 4j was ≥0...
January 4, 2017: Cancer Chemotherapy and Pharmacology
https://www.readbyqxmd.com/read/28049106/linking-uterine-serous-carcinoma-to-brca1-2-associated-cancer-syndrome-a-meta-analysis-and-case-report
#20
REVIEW
M M de Jonge, A L Mooyaart, M P G Vreeswijk, C D de Kroon, T van Wezel, C J van Asperen, V T H B M Smit, O M Dekkers, T Bosse
BACKGROUND: Uterine serous carcinoma (USC) shows greater morphological, clinical and molecular similarities to high-grade ovarian tubal serous carcinoma than to other types of endometrial cancer. As high-grade ovarian tubal serous carcinoma is known to be associated with BRCA1/2 pathogenic germline mutations (PMs), we aimed to explore whether USC is also a constituent of hereditary breast and ovarian cancer syndrome. METHODS: Pubmed, EMBASE and Web of Science were searched in July 2016 for articles assessing the association between USC and germline BRCA1/2-PMs...
December 31, 2016: European Journal of Cancer
keyword
keyword
85420
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"