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https://www.readbyqxmd.com/read/28227765/distribution-aware-estimation-of-the-minimum-achievable-uncertainty-in-diffusion-tensor-imaging-dti
#1
Andrea Duggento, Marco Giannelli, Carlo Tessa, Simona Lanzafame, Maria Guerrisi, Nicola Toschi, Andrea Duggento, Marco Giannelli, Carlo Tessa, Simona Lanzafame, Maria Guerrisi, Nicola Toschi, Nicola Toschi, Maria Guerrisi, Marco Giannelli, Carlo Tessa, Simona Lanzafame, Andrea Duggento
Diffusion tensor imaging (DTI) provides exquisite sensitivity to structural and microstructural characteristics of brain tissue, and is routinely employed in advanced neuroimaging applications. DTI is commonly performed using intrinsically noisy echo-planar imaging techniques and poses high demands both on scanner performance and on in-scanner subject time, which in turn is directly related to the number of diffusion-weighting direction one requires. While DTI-derived indices such as fractional anisotropy (FA), diffusion tensor trace and anisotropy mode have proven extremely useful in characterizing disease-related aberrations, their estimation is commonly performed using fitting routines that do not properly take into account MRI noise distribution...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227762/single-shot-turbo-spin-echo-acquisition-for-in-vivo-cardiac-diffusion-mri
#2
Masoud Edalati, Gregory R Lee, Hui Wang, Michael D Taylor, Yu Y Li, Masoud Edalati, Gregory R Lee, Hui Wang, Michael D Taylor, Yu Y Li, Masoud Edalati, Gregory R Lee, Michael D Taylor, Hui Wang, Yu Y Li
Diffusion MRI offers the ability to noninvasively characterize the microstructure of myocardium tissue and detect disease related pathology in cardiovascular examination. This study investigates the feasibility of in vivo cardiac diffusion MRI under free-breathing condition. A high-speed imaging technique, correlation imaging, is used to enable single-shot turbo spin echo for free-breathing cardiac data acquisition. The obtained in vivo cardiac diffusion-weighted images illustrate robust image quality and minor geometry distortions...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227488/statistical-evaluation-of-manual-segmentation-of-a-diffuse-low-grade-glioma-mri-dataset
#3
Meriem Ben Abdallah, Marie Blonski, Sophie Wantz-Mezieres, Yann Gaudeau, Luc Taillandier, Jean-Marie Moureaux, Meriem Ben Abdallah, Marie Blonski, Sophie Wantz-Mezieres, Yann Gaudeau, Luc Taillandier, Jean-Marie Moureaux, Luc Taillandier, Jean-Marie Moureaux, Marie Blonski, Yann Gaudeau, Sophie Wantz-Mezieres, Meriem Ben Abdallah
Software-based manual segmentation is critical to the supervision of diffuse low-grade glioma patients and to the optimal treatment's choice. However, manual segmentation being time-consuming, it is difficult to include it in the clinical routine. An alternative to circumvent the time cost of manual segmentation could be to share the task among different practitioners, providing it can be reproduced. The goal of our work is to assess diffuse low-grade gliomas' manual segmentation's reproducibility on MRI scans, with regard to practitioners, their experience and field of expertise...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227477/predictive-models-for-diffuse-low-grade-glioma-patients-under-chemotherapy
#4
Meriem Ben Abdallah, Marie Blonski, Sophie Wantz-Mezieres, Yann Gaudeau, Luc Taillandier, Jean-Marie Moureaux, Meriem Ben Abdallah, Marie Blonski, Sophie Wantz-Mezieres, Yann Gaudeau, Luc Taillandier, Jean-Marie Moureaux, Luc Taillandier, Jean-Marie Moureaux, Marie Blonski, Yann Gaudeau, Sophie Wantz-Mezieres, Meriem Ben Abdallah
Diffuse low-grade gliomas are rare primitive cerebral tumours of adults. These tumors progress continuously over time and then turn to a higher grade of malignancy associated with neurological disability, leading ultimately to death. Tumour size is one of the most important prognostic factors. Thus, it is of great importance to be able to assess the volume of the tumor during the patients' monitoring. MRI is nowadays the recommended modality to achieve this. Furthermore, if surgery remains the first option for diffuse low-grade gliomas, chemotherapy is increasingly used (before or after a possible surgery)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226714/a-unified-bayesian-based-compensated-magnetic-resonance-imaging
#5
Ameneh Boroomand, Edward Li, Mohammad Javad Shafiee, Masoom A Haider, Farzad Khalvati, Alexander Wong, Ameneh Boroomand, Edward Li, Mohammad Javad Shafiee, Masoom A Haider, Farzad Khalvati, Alexander Wong, Alexander Wong, Mohammad Javad Shafiee, Edward Li, Masoom A Haider, Ameneh Boroomand, Farzad Khalvati
Magnetic resonance (MR) images of higher quality is demanded for helping with more accurate and earlier diagnosis of different diseases. The overall quality of MR images is limited due to the existence of different degradation factors such as (1) MR aberrations due to intrinsic properties of the MR scanner, (2) magnetic field inhomogeneity, and (3) inherent MRI noise. Correcting each MRI degradation factor could be solely useful for the quality enhancement of MR imaging with a limited impact. Here, we propose a unified Bayesian based compensated MR imaging (CMRI) system which jointly corrects for the different aforementioned MR aberrations as well as MR noise and hence generates compensated MR (CMR) images with a higher quality...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226697/differences-in-white-matter-microstructure-between-parkinson-s-disease-patients-with-and-without-rem-sleep-behavior-disorder
#6
Farzaneh Rahmani, Mina Ansari, Atefeh Pooyan, Mehdi M Mirbagheri, Mohammad Hadi Aarabi, Farzaneh Rahmani, Mina Ansari, Atefeh Pooyan, Mehdi M Mirbagheri, Mohammad Hadi Aarabi, Mehdi M Mirbagheri, Farzaneh Rahmani, Atefeh Pooyan, Mina Ansari, Mohammad Hadi Aarabi
REM sleep behavior disorder (RBD) is characterized by increased muscle tone and violent limb movements and usually occurs during the early stages of Parkinson disease (PD). PD patients with RBD represent faster motor progression and cognitive dysfunction. We used diffusion imaging to assess which regions are involved in this phenomenon. In the current study, we computed Quantitative Anisotropic (QA), which is based on spin distribution function (SDF) that quantifies the density of diffusing water and is more sensitive to psychological differences between groups and also diffusion MRI connectometry to conduct group analysis between age and gender matched PD patients with and without RBD...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226694/multi-output-gaussian-processes-for-enhancing-resolution-of-diffusion-tensor-fields
#7
Hernan Dario Vargas Cardona, Alvaro A Orozco, Mauricio A Alvarez, Hernan Dario Vargas Cardona, Alvaro A Orozco, Mauricio A Alvarez, Hernan Dario Vargas Cardona, Mauricio A Alvarez, Alvaro A Orozco
Second order diffusion tensor (DT) fields are widely used in several clinical applications: brain fibers connections, diagnosis of neuro-degenerative diseases, image registration, brain conductivity models, etc. However, due to current acquisition protocols and hardware limitations in MRI machines, the diffusion magnetic resonance imaging (dMRI) data is obtained with low spatial resolution (1 or 2 mm(3) for each voxel). This issue can be significant, because tissue fibers are much smaller than voxel size. Interpolation has become in a successful methodology for enhancing spatial resolution of DT fields...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226693/comprehensive-reconstruction-of-multi-shot-multi-channel-diffusion-data-using-mussels
#8
Merry Mani, Vincent Magnotta, Douglas Kelley, Mathews Jacob, Merry Mani, Vincent Magnotta, Douglas Kelley, Mathews Jacob, Mathews Jacob, Vincent Magnotta, Merry Mani, Douglas Kelley
Echo planar imaging (EPI)-based magnetic resonance imaging (MRI) data are often corrupted by Nyquist ghost artifacts resulting from odd-even shifts of the EPI read-outs. Algorithms that corrects for the Nyquist ghost artifacts rely on calibration scans that are collected prior to the data acquisition. However, a more complex pattern of ghosting artifacts arises when diffusion-weighted data are acquired using segmented k-space EPI read-outs. The additional under-sampling present in the segmented acquisitions and the inter-shot motion during diffusion weighted acquistion cause ghosting artifacts in addition to the EPI ghosting arising from odd-even shifts...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226692/tle-lateralization-using-whole-brain-structural-connectivity
#9
Esmaeil Davoodi-Bojd, Kost V Elisevich, Jason Schwalb, Ellen Air, Hamid Soltanian-Zadeh, Esmaeil Davoodi-Bojd, Kost V Elisevich, Jason Schwalb, Ellen Air, Hamid Soltanian-Zadeh, Hamid Soltanian-Zadeh, Kost V Elisevich, Esmaeil Davoodi-Bojd, Ellen Air, Jason Schwalb
A prerequisite of temporal lobe epilepsy (TLE) surgery is to lateralize the disease. Recent studies have shown the capability of diffusion weighted MRI (DWMRI) in lateralizing TLE patients. This has been achieved by analyzing diffusion parameters of specific white matter tracts or regions known to be involved in the disease; however, other brain regions and connections have not been investigated for TLE lateralization. Whole brain structural connectivity using DWMRI provides a wealth of information regarding the structural connections in the brain...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226446/a-challenging-issue-detection-of-white-matter-hyperintensities-in-neonatal-brain-mri
#10
Baptiste Morel, Yongchao Xu, Alessio Virzi, Thierry Geraud, Catherine Adamsbaum, Isabelle Bloch, Baptiste Morel, Yongchao Xu, Alessio Virzi, Thierry Geraud, Catherine Adamsbaum, Isabelle Bloch, Alessio Virzi, Yongchao Xu, Thierry Geraud, Catherine Adamsbaum, Isabelle Bloch, Baptiste Morel
The progress of magnetic resonance imaging (MRI) allows for a precise exploration of the brain of premature infants at term equivalent age. The so-called DEHSI (diffuse excessive high signal intensity) of the white matter of premature brains remains a challenging issue in terms of definition, and thus of interpretation. We propose a semi-automatic detection and quantification method of white matter hyperintensities in MRI relying on morphological operators and max-tree representations, which constitutes a powerful tool to help radiologists to improve their interpretation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225646/conventional-and-zoomit-dwi-for-evaluation-of-testis-in-patients-with-ipsilateral-varicocele
#11
İsmail Okan Yıldırım, Semih Sağlık, Hüseyin Çelik
OBJECTIVE: The current study aimed to investigate the effects of varicocele on testis parenchyma by using ZOOMit DWI and conventional DWI and to compare both diffusion methods. SUBJECTS AND METHODS: Forty-five patients with unilateral varicocele diagnosed by physical examination and color Doppler ultrasound between July 2015 and December 2015 and 32 healthy volunteers were included in the study. ZOOMit and conventional DWI were performed for all patients with a 3-T MRI scanner...
February 22, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28225579/intravoxel-incoherent-motion-mri-assessment-of-chemoradiation-induced-pelvic-bone-marrow-changes-in-cervical-cancer-and-correlation-with-hematological-toxicity
#12
Elaine Yuen Phin Lee, Jose Angelo Udal Perucho, Vince Vardhanabhuti, Jian He, Steven Wai Kwan Siu, Siew Fei Ngu, Nina A Mayr, William T C Yuh, Queenie Chan, Pek-Lan Khong
PURPOSE: To investigate bone marrow changes after chemoradiation (CRT) using intravoxel incoherent motion magnetic resonance imaging (IVIM-MRI) and correlate imaging changes with hematological toxicity (HT) in patients with locally advanced cervical cancer. MATERIALS AND METHODS: Thirty-nine patients with newly diagnosed cervical cancer were prospectively recruited for two sequential 3.0T IVIM-MRI studies: before treatment (MRI-1) and 3-4 weeks after standardized CRT (MRI-2)...
February 22, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28225569/hepatic-alanine-differentiates-nonalcoholic-steatohepatitis-from-simple-steatosis-in-humans-and-mice-a-proton-mr-spectroscopy-study-with-long-echo-time
#13
Tae-Hoon Kim, Hong Young Jun, Ki-Jong Kim, Young Hwan Lee, Myeung Su Lee, Keum Ha Choi, Ki Jung Yun, Yong Yeon Jeong, Chung Hwan Jun, Eun Young Cho, Kwon-Ha Yoon
PURPOSE: To evaluate the hepatic metabolic alterations in nonalcoholic fatty liver disease (NAFLD) by using (1) H-MRS (proton magnetic resonance spectroscopy) with long echo time and to test the reproducibility of human study in an animal model. Liver biopsy is the gold standard for diagnosing NAFLD but with practical constraints. (1) H-MRS allows in vivo assessment of hepatocellular metabolism and has shown potential for biochemical differentiation in diffuse liver disease. MATERIALS AND METHODS: In all, 32 subjects (11 patients with nonalcoholic steatohepatitis [NASH], 15 with simple steatosis [SS], and six healthy controls) were studied...
February 22, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28225568/liver-histology-and-diffusion-weighted-mri-in-children-with-nonalcoholic-fatty-liver-disease-a-magnet-study
#14
Paul Manning, Paul Murphy, Kang Wang, Jonathan Hooker, Tanya Wolfson, Michael S Middleton, Kimberly P Newton, Cynthia Behling, Hannah I Awai, Janis Durelle, Melissa N Paiz, Jorge E Angeles, Diana De La Pena, J Allen McCutchan, Jeffrey B Schwimmer, Claude B Sirlin
PURPOSE: To determine potential associations between histologic features of pediatric nonalcoholic fatty liver disease (NAFLD) and estimated quantitative magnetic resonance diffusion-weighted imaging (DWI) parameters. MATERIALS AND METHODS: This prospective, cross-sectional study was performed as part of the Magnetic Resonance Assessment Guiding NAFLD Evaluation and Treatment (MAGNET) ancillary study to the Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN)...
February 22, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28224172/multi-parametric-mri-findings-of-granulomatous-prostatitis-developing-after-intravesical-bacillus-calmette-gu%C3%A3-rin-therapy
#15
Josh Gottlieb, Robert Princenthal, Martin I Cohen
PURPOSE: To evaluate the multi-parametric MRI (mpMRI) findings in patients with biopsy-proven granulomatous prostatitis and prior Bacillus Calmette-Guérin (BCG) exposure. MATERIALS AND METHODS: MRI was performed in six patients with pathologically proven granulomatous prostatitis and a prior history of bladder cancer treated with intravesical BCG therapy. Multi-parametric prostate MRI images were recorded on a GE 750W or Philips Achieva 3.0 Tesla MRI scanner with high-resolution, small-field-of-view imaging consisting of axial T2, axial T1, coronal T2, sagittal T2, axial multiple b-value diffusion (multiple values up to 1200 or 1400), and dynamic contrast-enhanced 3D axial T1 with fat suppression sequence...
February 21, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28223963/corrigendum-feasibility-and-diagnostic-accuracy-of-ischemic-stroke-territory-recognition-based-on-two-dimensional-projections-of-three-dimensional-diffusion-mri-data
#16
Jana Katharina Wrosch, Bastian Volbers, Philipp Gölitz, Daniel Frederic Gilbert, Stefan Schwab, Arnd Dörfler, Johannes Kornhuber, Teja Wolfgang Groemer
[This corrects the article on p. 239 in vol. 6, PMID: 26635717.].
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28223932/cerebrospinal-fluid-levels-of-amyloid-beta-1-43-mirror-1-42-in-relation-to-imaging-biomarkers-of-alzheimer-s-disease
#17
Ina S Almdahl, Camilla Lauridsen, Per Selnes, Lisa F Kalheim, Christopher Coello, Beata Gajdzik, Ina Møller, Marianne Wettergreen, Ramune Grambaite, Atle Bjørnerud, Geir Bråthen, Sigrid B Sando, Linda R White, Tormod Fladby
Introduction: Amyloid beta 1-43 (Aβ43), with its additional C-terminal threonine residue, is hypothesized to play a role in early Alzheimer's disease pathology possibly different from that of amyloid beta 1-42 (Aβ42). Cerebrospinal fluid (CSF) Aβ43 has been suggested as a potential novel biomarker for predicting conversion from mild cognitive impairment (MCI) to dementia in Alzheimer's disease. However, the relationship between CSF Aβ43 and established imaging biomarkers of Alzheimer's disease has never been assessed...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28223480/in-vivo-imaging-reveals-that-pregabalin-inhibits-cortical-spreading-depression-and-propagation-to-subcortical-brain-structures
#18
Stuart M Cain, Barry Bohnet, Jeffrey LeDue, Andrew C Yung, Esperanza Garcia, John R Tyson, Sascha R A Alles, Huili Han, Arn M J M van den Maagdenberg, Piotr Kozlowski, Brian A MacVicar, Terrance P Snutch
Migraine is characterized by severe headaches that can be preceded by an aura likely caused by cortical spreading depression (SD). The antiepileptic pregabalin (Lyrica) shows clinical promise for migraine therapy, although its efficacy and mechanism of action are unclear. As detected by diffusion-weighted MRI (DW-MRI) in wild-type (WT) mice, the acute systemic administration of pregabalin increased the threshold for SD initiation in vivo. In familial hemiplegic migraine type 1 mutant mice expressing human mutations (R192Q and S218L) in the CaV2...
February 21, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28223037/asymmetric-dopaminergic-degeneration-and-levodopa-alter-functional-corticostriatal-connectivity-bilaterally-in-experimental-parkinsonism
#19
Cyril Monnot, Xiaoqun Zhang, Sahar Nikkhou-Aski, Peter Damberg, Per Svenningsson
Asymmetric dopamine loss is commonly found in early Parkinson's disease (PD), but its effects on functional networks have been difficult to delineate in PD patients because of variations in age, disease duration and therapy. Here we used unilateral 6-hydroxydopamine-lesioned (6-OHDA) rats and controls and treated them with a single intraperitoneal injection of levodopa (L-DOPA) before performing diffusion weighted MRI and resting state functional MRI (rs-fMRI). In accordance with a neurodegeneration of the nigrostriatal dopaminergic pathway, diffusion tensor imaging showed increased radial diffusivity and decreased fractional anisotropy in the lesioned substantia nigra...
February 18, 2017: Experimental Neurology
https://www.readbyqxmd.com/read/28220831/the-distribution-of-the-apparent-diffusion-coefficient-as-an-indicator-of-the-response-to-chemotherapeutics-in-ovarian-tumour-xenografts
#20
Monique C Tourell, Ali Shokoohmand, Marietta Landgraf, Nina P Holzapfel, Patrina S P Poh, Daniela Loessner, Konstantin I Momot
Diffusion-weighted magnetic resonance imaging (DW-MRI) was used to evaluate the effects of single-agent and combination treatment regimens in a spheroid-based animal model of ovarian cancer. Ovarian tumour xenografts grown in non-obese diabetic/severe-combined-immunodeficiency (NOD/SCID) mice were treated with carboplatin or paclitaxel, or combination carboplatin/paclitaxel chemotherapy regimens. After 4 weeks of treatment, tumours were extracted and underwent DW-MRI, mechanical testing, immunohistochemical and gene expression analyses...
February 21, 2017: Scientific Reports
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