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Chrysa D Papadaniil, Vasiliki E Kosmidou, Anthoula Tsolaki, Magda Tsolaki, Ioannis Yiannis Kompatsiaris, Leontios J Hadjileontiadis
Precise preclinical detection of dementia for effective treatment and stage monitoring is of great importance. Miscellaneous types of biomarkers, e.g., biochemical, genetic, neuroimaging, and physiological, have been proposed to diagnose Alzheimer's disease (AD), the usual suspect behind manifested cognitive decline, and mild cognitive impairment (MCI), a neuropathology prior to AD that does not affect cognitive functions. Event related potential (ERP) methods constitute a non-invasive, inexpensive means of analysis and have been proposed as sensitive biomarkers of cognitive impairment; besides, various ERP components are strongly linked with working memory, attention, sensory processing and motor responses...
October 1, 2016: Brain Research
Rishi V A Sheorajpanday, Peter Marien, Arie J T M Weeren, Guy Nagels, Jos Saerens, Michel J A M van Putten, Peter P De Deyn
INTRODUCTION: Vascular cognitive impairment, no dementia (vCIND) is a prevalent and potentially preventable disorder. Clinical presof the small vessel subcortical subtype may be insidious and difficult to diagnose in the initial stage. We investigated electroencephalographic sources of subcortical vCIND in comparison to amnesic multidomain mild cognitive impairment (amdMCI) to determine the additional diagnostic value of quantitative electroencephalograhy (EEG) in this setting. METHODS: Fifty-seven community residing patients with an uneventful central neurological history and first presentation of cognitive decline without dementia were included, 35 patients were diagnosed with vCIND and 22 with amdMCI...
April 2013: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
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