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Milos Sovak, Allen L Seligson, Renata Kucerova, Marie Bienova, Marian Hajduch, Milan Bucek
BACKGROUND: Fluridil, a novel topical antiandrogen, suppresses the human androgen receptor. While highly hydrophobic and hydrolytically degradable, it is systemically nonresorbable. In animals, fluridil demonstrated high local and general tolerance. OBJECTIVE: To evaluate the safety and efficacy of a topical anti- androgen, fluridil, in male androgenetic alopecia. METHODS: In 20 men, for 21 days, occlusive forearm patches with 2, 4, and 6% fluridil, isopropanol, and/or vaseline were applied...
August 2002: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
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