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platelet rich plasma for hair

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https://www.readbyqxmd.com/read/29904992/platelet-rich-plasma-for-the-management-of-hair-loss-better-alone-or-in-combination
#1
Eduardo Anitua, Ander Pino, Pedro Jaén, Mª Rogelia Navarro
Platelet-rich plasma (PRP) and autologous protein-based treatments have recently emerged as a potential therapeutic approach for hair loss-related disorders including androgenetic alopecia and alopecia areata. The safety and efficacy of repeated intradermal injections of PRP has proved to promote hair growth in a number of randomized clinical trials. Biologically active proteins and cytokines released upon platelet activation have shown to induce folliculogenesis and activate the anagen growing phase of dormant bulbs...
June 14, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29797431/efficacy-of-non-surgical-treatments-for-androgenetic-alopecia-a-systematic-review-and-network-meta-analysis
#2
REVIEW
Aditya K Gupta, Rachel R Mays, Michelle S Dotzert, Sarah G Versteeg, Neil H Shear, Vincent Piguet
Androgenetic alopecia, or male/female pattern baldness, is the most common type of progressive hair loss disorder. The aim of this paper is to review recent advances in non-surgical treatments for androgenetic alopecia and identify the most effective treatments. A network meta-analysis (NMA) was conducted of the available literature of the six most common non-surgical treatment options for treating androgenetic alopecia in both men and women; dutasteride 0.5mg, finasteride 1mg, low level laser therapy (LLLT), minoxidil 2%, minoxidil 5% and platelet rich plasma (PRP)...
May 24, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29790267/systematic-review-of-platelet-rich-plasma-prp-preparation-and-composition-for-the-treatment-of-androgenetic-alopecia
#3
REVIEW
MaryJo E Kramer, Terrence C Keaney
BACKGROUND: Platelet-rich plasma (PRP) injections have gained popularity in dermatology practice as a treatment for hair loss. As an autologous blood product, PRP is categorized as a minimally manipulated tissue by the U.S. Food and Drug Administration (FDA) and thus evades extensive regulation. As a result, there is a lack of standardization of its preparation and final composition. OBJECTIVE: This study aims to provide a systematic review of the various PRP preparation protocols and PRP compositions utilized in clinical trials for the treatment of hair loss...
May 22, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29707872/platelet-rich-plasma-on-female-androgenetic-alopecia-tested-on-10-patients
#4
Michela Starace, Aurora Alessandrini, Carmine D'Acunto, Davide Melandri, Francesca Bruni, Annalisa Patrizi, Bianca Maria Piraccini
BACKGROUND: Recently, platelet-rich plasma (PRP) injection has been proposed as a potential adjuvant therapy to treat androgenetic alopecia. AIMS: Investigate the efficacy, tolerability, and clinical improvement of PRP for the treatment of female AGA. PATIENTS/METHODS: A total of 10 female patients affected by AGA and not responding to treatment with minoxidil and/or oral antiandrogens were enrolled. The clinical improvement was evaluated by pull test, global photographs, and Trichoscan at weeks 9, 12, and 24, and hair measurements were performed at baseline and 12 and 24 weeks after the first session...
April 30, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29564738/platelet-rich-plasma-therapy-and-reproductive-medicine
#5
EDITORIAL
Adriana Bos-Mikich, Ricardo de Oliveira, Nilo Frantz
Reports on clinical uses of platelet-rich plasma (PRP) have dramatically increased in the last decade. Indications for PRP therapy range from muscle and skeletal injuries to hair re-growth. More recently evidences have shown its positive effects in promoting endometrial and follicular growth and gestation in assisted reproduction cycles. We discuss the putative role of PRP on endometrial receptivity, with a brief history of its applications in research and clinical therapies. Despite its widespread uses in medicine, the mechanisms through which PRP exerts its regenerative effects are only postulated, not based on scientific data...
March 21, 2018: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29554209/introducing-platelet-rich-stroma-platelet-rich-plasma-prp-and-stromal-vascular-fraction-svf-combined-for-the-treatment-of-androgenetic-alopecia
#6
Hieronymus P Stevens, Simone Donners, Julia de Bruijn
Background: Androgenetic alopecia (AGA) is characterized by miniaturization of the hair follicles gradually causing conversion of terminal hairs into vellus hairs, leading to progressive reduction of the density of hair on the scalp. Approved therapeutic options are limited and show side effects. Objectives: To evaluate injections of stromal vascular fraction (SVF), which is rich in adipose-derived stromal cells (ASCs) in combination with platelet-rich plasma (PRP) in the upper scalp as a new autologous treatment option for AGA...
March 15, 2018: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29508105/decellularized-amnion-scaffold-with-activated-prp-a-new-paradigm-dressing-material-for-burn-wound-healing
#7
Jeevitaa Kshersagar, Ravi Kshirsagar, Shashikant Desai, Raghvendra Bohara, Meghnad Joshi
Direct application of amnion has greater risk of immunological rejection and infection. Decellularization is an effective method to lower the risk of immune complications and infections. The bioreactor assembly with multiple cassettes was designed for decellurization of multiple amnions with different cell types simultaneously in single run. A detergent-based protocol was modified to remove all cellular components from amnion and diminish the DNA content to render it non-immunogenic. Amnion (n = 10) were treated with 2% sodium dodecyl sulphate (SDS), 5% dimethyl sulfoxide (DMSO) and 2% sodium deoxycholeate (SD)...
March 5, 2018: Cell and Tissue Banking
https://www.readbyqxmd.com/read/29473280/effect-of-platelets-rich-plasma-on-scalp-hair-diameter
#8
Muhammad Ahmad
OBJECTIVES: To measure the effects of platelet-rich plasma (PRP) on hair diameter in Pakistani population. MATERIALS AND METHODS: The study was conducted in a private setup in the adult patients undergoing PRP treatment. Baseline platelets count was noted for each patient. PRP was prepared using a commercial kit. Three PRP injections were administered in the scalp at 0, 1, and 3 months of interval. The hair caliber was measured in the mid-scalp area using a separate stencil for each patient...
February 23, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29457005/effectiveness-of-platelet-rich-plasma-for-androgenetic-alopecia-a-review-of-the-literature
#9
REVIEW
Jessica Cervantes, Marina Perper, Lulu L Wong, Ariel E Eber, Alexandra C Villasante Fricke, Tongyu Cao Wikramanayake, Joaquin J Jimenez
Androgenetic alopecia (AGA) is a hair loss disorder affecting 80% of men and 50% of women throughout their lifetime. Therapies for AGA are limited and there is no cure. There is a high demand for hair restoration. Platelet-rich plasma (PRP), a treatment modality shown to promote wound healing, has also been explored as a treatment for AGA. This literature review was conducted to assess the effectiveness of PRP treatment for AGA. Twelve studies conducted from 2011 to 2017 were evaluated and summarized by study characteristics, mode of preparation, and treatment protocols...
January 2018: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29440850/a-meta-analysis-on-evidence-of-platelet-rich-plasma-for-androgenetic-alopecia
#10
Salvatore Giordano, Marco Romeo, Pietro di Summa, Andre' Salval, Petteri Lankinen
Background: Platelet-rich plasma (PRP) treatment has gained popularity among different surgical specialities for improving various conditions. Androgenetic alopecia (AGA) is a common disorder, with possible psychosocial implications. Plastic surgeons have increased the practice of PRP injections for hair restoration. A meta-analysis on this topic was performed comparing local injection of PRP versus control to investigate the efficacy of local PRP injections in AGA. Methods: We performed a systematic literature search...
January 2018: International Journal of Trichology
https://www.readbyqxmd.com/read/29273100/an-overview-of-the-biology-of-platelet-rich-plasma-and-microneedling-as-potential-treatments-for-alopecia-areata
#11
REVIEW
Lauren C Strazzulla, Lorena Avila, Kristen Lo Sicco, Jerry Shapiro
Platelet-rich plasma and microneedling have been investigated recently as potential therapeutic options for the treatment of hair disorders. Evidence from laboratory studies indicates that these treatments enhance growth factor production that in turn facilitates hair follicle development and cycling. Several small studies and case reports have presented encouraging findings regarding the use of these treatments for alopecia areata. Future investigations will be needed to validate these therapeutic techniques for patients with alopecia areata and further refine which subtypes of the disease these methods are best indicated for...
January 2018: Journal of Investigative Dermatology. Symposium Proceedings
https://www.readbyqxmd.com/read/29228441/correlation-between-individual-inflammation-genetic-profile-and-platelet-rich-plasma-efficacy-in-hair-follicle-regeneration-a-pilot-study-reveals-prognostic-value-of-il-1a-polymorphism
#12
F Rossano, S Di Martino, L Iodice, M Di Paolo, S Misso, R Tomeo, A M Marini, R Brugnone, S Marlino, A Santorelli, R Di Francia
OBJECTIVE: Hair loss generates severe psychosocial implications. To date, exploring the prognostic factors of possible clinical benefit of autologous blood concentrate platelet rich plasma (PRP) was failed. The aim of our pilot study was to explore the correlation between the individual inflammation genetic profile and PRP efficacy in the treatment of hair follicle regeneration. PATIENTS AND METHODS: 41 volunteers (25 men, 16 women) took part in this retrospective study...
November 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29204389/platelet-rich-plasma-by-single-spin-process-in-male-pattern-androgenetic-alopecia-is-it-an-effective-treatment
#13
Azin Ayatollahi, Hamed Hosseini, Majid Shahdi, Saman AhmadNasrollahi, Mansour NassiriKashani, Somaye Yadangi, Farid H Firooz, Alireza Firooz
Introduction and Objective: Platelet-rich plasma (PRP) is an autologous preparation of platelets in concentrated plasma. The platelet is a natural source of different growth factors and cytokines. These growth factors act on stem cells in the bulge area of the follicles and stimulate the development of new follicles, and promote neovascularization. The aim of this study was to investigate the efficacy and safety of PRP injections in androgenetic alopecia (AGA) in men. Patients and Methods: Fifteen male patients (mean age: 39 ± 9...
November 2017: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/29194786/microneedling-for-the-treatment-of-hair-loss
#14
REVIEW
R M Fertig, A C Gamret, J Cervantes, A Tosti
Microneedling is a minimally invasive dermatological procedure in which fine needles are rolled over the skin to puncture the stratum corneum. This therapy is used to induce collagen formation, neovascularization and growth factor production of treated areas. It has been used in a wide range of dermatologic conditions, including androgenetic alopecia (AGA) and alopecia areata, among others. While there are a limited number of studies examining this therapy in the use of hair loss, microneedling has been successfully paired with other hair growth promoting therapies, such as minoxidil, platelet-rich plasma and topical steroids, and shown to stimulate hair follicle growth...
April 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29141069/a-novel-multi-targeting-approach-to-treating-hair-loss-using-standardized-nutraceuticals
#15
Patricia K Farris, Nicole Rogers, Amy McMichael, Sophia Kogan
<p>Hair loss is a complicated problem that causes significant concern for those who are affected. Patients seeking medical treatment have limited options that include topical minoxidil and oral finasteride. While these treatments are backed by long term clinical use and research outcomes, many patients find topical minoxidil difficult to incorporate into their daily routine and some are concerned with the side effects associated with finasteride. In the office setting, patients may be treated with more invasive procedures such as platelet-rich plasma injections (PRP) and hair transplantation, treatments that often must be repeated and can lead to a costly investment...
November 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29130636/efficacy-of-subcutaneous-injection-of-platelet-rich-plasma-in-alopecia-a-clinical-and-histological-pilot-study-on-a-rat-model-with-a-six-month-long-term-follow-up-experience
#16
Sophie Orliac, Jean-Michel Serfaty, Anne Perozziello, Olivier Zurlinden, Liliane Louedec, Benjamin Dallaudière
PURPOSE: To assess the potential of platelet-rich plasma (PRP) subcutaneous injection of to treat alopecia and to evaluate local toxicity. MATERIALS-METHODS: Twelve Hairless rats were used. At D0, we performed systematic clinical examination and divided the rat back into four quadrants (Q). We initiated subcutaneous injection using either PRP in PRPQ+, platelet-poor plasma (PPP) in PPPQ+, physiological serum (PS) in PSQ+, or no treatment (Q4). At D7, D14, D21, and D28 but also second month (M2), M3, M4, M5, rats had exactly the same injection procedure...
April 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29108548/new-generation-therapies-for-the-treatment-of-hair-loss-in-men
#17
REVIEW
Neil S Sadick
Hair loss affects millions of people worldwide and can have devastating effects on an individual's psychoemotional well-being. Today hair restoration technologies through hair transplantation have advanced with the use of robots and follicular unit extraction/grafting that can offer patients excellent clinical results. Adjuvant modalities, such as platelet-rich plasma injections, lasers, and stem cells, can further enhance durability, health, and appearance of hair transplants.
January 2018: Dermatologic Clinics
https://www.readbyqxmd.com/read/29103820/an-overview-of-the-biology-of-platelet-rich-plasma-and-microneedling-as-potential-treatments-for-alopecia-areata
#18
REVIEW
Lauren C Strazzulla, Lorena Avila, Kristen Lo Sicco, Jerry Shapiro
Platelet-rich plasma and microneedling have been investigated recently as potential therapeutic options for the treatment of hair disorders. Evidence from laboratory studies indicates that these treatments enhance growth factor production that in turn facilitates hair follicle development and cycling. Several small studies and case reports have presented encouraging findings regarding the use of these treatments for alopecia areata. Future investigations will be needed to validate these therapeutic techniques for patients with alopecia areata and further refine which subtypes of the disease these methods are best indicated for...
November 3, 2017: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/29101437/comparison-of-the-efficacy-of-homologous-and-autologous-platelet-rich-plasma-prp-for-treating-androgenic-alopecia
#19
Bilsev Ince, Mehmet Emin Cem Yildirim, Mehmet Dadaci, Mustafa Cihat Avunduk, Nedim Savaci
BACKGROUND: Androgenetic alopecia (AGA), the most common cause of hair loss in both sexes, accounts for 95% of all cases of hair loss. Although the literature has suggested that both nonactivated (n-PRP) and activated autologous (a-PRP) PRP can be used to treat AGA, we did not find any study investigating the use of homologous PRP (h-PRP) for this purpose. Also, to the best of our knowledge, there are no studies comparing the efficacy of h-PRP, a-PRP, or n-PRP on AGA therapy. OBJECTIVES: The aim of this study was to compare the increase in hair density, average number of platelets, complications, preparation, and duration of application in the treatment of AGA using a-PRP, n-PRP, and h-PRP...
February 2018: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29064980/hair-transplantation-controversies
#20
REVIEW
Marc R Avram, Robert Finney, Nicole Rogers
BACKGROUND: Hair transplant surgery creates consistently natural appearing transplanted hair for men. It is increasingly popular procedure to restore natural growing hair for men with hair loss. OBJECTIVE: To review some current controversies in hair transplant surgery. MATERIALS AND METHODS: Review of the English PubMed literature and specialty literature in hair transplant surgery. RESULTS: Some of the controversies in hair transplant surgery include appropriate donor harvesting technique including elliptical donor harvesting versus follicular unit extraction whether manual versus robotic, the role of platelet-rich plasma and low-level light surgery in hair transplant surgery...
November 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
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