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platelet rich plasma for hair

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https://www.readbyqxmd.com/read/28523261/rejuvenation-using-platelet-rich-plasma-and-lipofilling-for-vaginal-atrophy-and-lichen-sclerosus
#1
Seok Hwan Kim, Eun Soo Park, Tae Hee Kim
Vaginal atrophy is a common condition among peri- and post-menopausal women. Symptoms of vaginal dryness, pruritus, irritation, loss of subcutaneous fat, sparse pubic hair and dyspareunia occur due to decreased estrogen level. Estrogen-based treatments are effective. But many patients are reluctant to be treated due to health concerns. As alternatives, we explored the efficacy of platelet-rich plasma (PRP) and lipofilling. A 67-year-old female patient with vaginal atrophy was referred to our department. Treatment using estrogen cream had failed to improve patient's symptoms...
April 2017: Journal of Menopausal Medicine
https://www.readbyqxmd.com/read/28503741/the-effect-of-autologous-activated-platelet-rich-plasma-injection-on-female-pattern-hair-loss-a-randomized-placebo-controlled-study
#2
Abeer Attia Tawfik, Mai Abdel Raouf Osman
BACKGROUND: Hair is an essential part of a woman's appearance and attractiveness. This is reflected in the predominantly psychological morbidity that can be associated with female pattern hair loss. Platelet-rich plasma(PRP) has been used in numerous fields of medicine. Recently, PRP has received growing attention as a potential therapeutic tool for hair loss. OBJECTIVE: To evaluate the efficacy and safety of autologous platelet-rich plasma in the treatment of female pattern hair loss...
May 14, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28442778/as-a-carrier-transporter-for-hair-follicle-reconstitution-platelet-rich-plasma-promotes-proliferation-and-induction-of-mouse-dermal-papilla-cells
#3
Shun-E Xiao, Yong Miao, Jin Wang, Wei Jiang, Zhe-Xiang Fan, Xiao-Min Liu, Zhi-Qi Hu
Morphogenesis of hair follicles during development and in hair reconstitution assays involves complex interactions between epithelial cells and dermal papilla cells (DPCs). DPCs may be a source of cells for hair regeneration in alopecia patients. Reconstitution of engineered hair follicles requires in vitro culture of trichogenic cells, a three-dimensional scaffolds, and biomolecular signals. However, DPCs tend to lose their biological activity when cultured as trichogenic cells, and scaffolds currently used for hair follicle regeneration lack biological efficiency and biocompatibility...
April 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28423680/a-bioartificial-dermal-regeneration-template-promotes-skin-cell-proliferation-in-vitro-and-enhances-large-skin-wound-healing-in-vivo
#4
Peng Chang, Bingyu Guo, Qiang Hui, Xiaoyan Liu, Kai Tao
A novel bioartificial dermal regeneration template has been developed using platelet-rich plasma and acellular animal skin collagen sponge for the treatment of larger area and full thickness skin wounds. This platelet-rich plasma-collagen sponge keeps native skin structure and contains huge amounts of growth factors. The effect of this bioartificial dermal regeneration template was tested in vitro and in vivo via a mimic poor wound healing process by adding collagenase I into cell culture medium or the wound area...
April 11, 2017: Oncotarget
https://www.readbyqxmd.com/read/28375977/platelet-rich-plasma-for-the-treatment-of-female-pattern-hair-loss-a-patient-survey
#5
Mary E Laird, Kristen I Lo Sicco, Michael L Reed, Nooshin K Brinster
No abstract text is available yet for this article.
April 3, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28271918/platelet-rich-plasma-for-treatment-of-non-scarring-hair-loss-systematic-review-of-literature
#6
Azin Ayatollahi, Hamed Hosseini, Jaleh Gholami, Babak Mirminachi, FaridHossein Firooz, Alireza Firooz
BACKGROUND: Although there are many studies showing the role of platelet rich plasma (PRP) in bone grafts, teeth osteosynthesis, and wound healing, there have been little peer reviewed studies about the safety and efficacy of PRP application in the treatment of hair loss. MATERIALS AND METHODS: In this systematic review, we searched Ovid Medline, Scopus and Web of Knowledge till November 2015 for human studies evaluating the efficacy of PRP for the treatment of non-cicatricial alopecia...
March 23, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28221183/the-effect-of-plasma-rich-in-growth-factors-on-pattern-hair-loss-a-pilot-study
#7
Eduardo Anitua, Ander Pino, Nahikari Martinez, Gorka Orive, Daniel Berridi
BACKGROUND: Autologous growth factors have proved to promote tissue regeneration in various medical fields. Recent findings suggest that platelet rich plasma may also play an important role in hair follicle restoration. OBJECTIVE: The objective of this study was to evaluate the safety and clinical efficacy of plasma rich in growth factors (PRGFs) for the treatment of androgenetic alopecia (AGA). MATERIALS AND METHODS: Five PRGF injections were administered over 19 patients with AGA...
May 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28216604/evaluation-of-not-activated-and-activated-prp-in-hair-loss-treatment-role-of-growth-factor-and-cytokine-concentrations-obtained-by-different-collection-systems
#8
Pietro Gentile, John P Cole, Megan A Cole, Simone Garcovich, Alessandra Bielli, Maria Giovanna Scioli, Augusto Orlandi, Chiara Insalaco, Valerio Cervelli
Platelet rich plasma (PRP) was tested as a potential therapy for androgenetic alopecia (AGA) through two different clinical protocols in which one population (18 participants) received half-head treatment with autologous non-activated PRP (A-PRP) produced by CPunT Preparation System (Biomed Device, Modena, Italy) and the other half-head with placebo, and a second separated population in which all participants (n = 6, 3 participants per group) received treatment with calcium-activated PRP (AA-PRP) produced from one of two different PRP collection devices (Regen Blood Cell Therapy or Arthrex Angel System)...
February 14, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27922680/identification-of-key-genes-induced-by-platelet-rich-plasma-in-human-dermal-papilla-cells-using-bioinformatics-methods
#9
Haiyan Shen, Hanxiao Cheng, Haihua Chen, Jufang Zhang
Dermal papilla cells (DPCs) are located at the base of hair follicles, and are known to induce hair follicle regeneration. Platelet-rich plasma (PRP) functions in hair follicle regeneration. To investigate the influence of PRP on DPCs, the present study analyzed RNA‑seq data of human hair dermal papilla cells (HHDPCs) that were treated or untreated by PRP. The data included in the RNA‑seq were from two normal and two treated HHDPC samples. Following identification by Cuffdiff software, differentially expressed genes (DEGs) underwent enrichment analyses, and protein-protein interaction networks were constructed using Cytoscape software...
January 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/27918883/platelet-rich-plasma-in-androgenic-alopecia-indications-technique-and-potential-benefits
#10
REVIEW
Elie M Ferneini, Daniel Beauvais, Concetta Castiglione, Moniek V Ferneini
PURPOSE: The purpose of this study was to provide an overview of platelet-rich plasma (PRP) injected into the scalp for the management of androgenic alopecia. MATERIALS AND METHODS: A literature review was performed to evaluate the benefits of PRP in androgenic alopecia. RESULTS: Hair restoration has been increasing. PRP's main components of platelet-derived growth factor, transforming growth factor, and vascular endothelial growth factor have the potential to stimulate hard and soft tissue wound healing...
April 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27791311/platelets-rich-plasma-versus-minoxidil-5-in-treatment-of-alopecia-areata-a-trichoscopic-evaluation
#11
RANDOMIZED CONTROLLED TRIAL
Moustafa A El Taieb, Hassan Ibrahim, Essam A Nada, Mai Seif Al-Din
Alopecia areata is a common cause of nonscarring alopecia that occurs in a patchy, confluent, or diffuse pattern. Dermoscopy is a noninvasive technique for the clinical diagnosis of many skin diseases. Topical minoxidil solution 5% and platelet rich plasma are important modalities used in treatment of alopecia areata. We aimed to evaluate the efficacy of PRP versus topical minoxidil 5% in the treatment of AA by clinical evaluation and trichoscopic examination. Ninety patients were allocated into three groups; the first was treated with topical minoxidil 5% solution, the second with platelets rich plasma injections, and the third with placebo...
January 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/27770310/treating-alopecia-areata-current-practices-versus-new-directions
#12
REVIEW
Aditya K Gupta, Jessie Carviel, William Abramovits
Alopecia areata (AA) is non-scarring hair loss resulting from an autoimmune disorder. Severity varies from patchy hair loss that often spontaneously resolves to severe and chronic cases that can progress to total loss of scalp and body hair. Many treatments are available; however, the efficacy of these treatments has not been confirmed, especially in severe cases, and relapse rates are high. First-line treatment often includes corticosteroids such as intralesional or topical steroids for mild cases and systemic steroids or topical immunotherapy with diphenylcyclopropenone or squaric acid dibutylester in severe cases...
February 2017: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27631460/a-mechanistic-model-of-platelet-rich-plasma-treatment-for-androgenetic-alopecia
#13
REVIEW
Aditya K Gupta, Jessie Carviel
BACKGROUND: Platelet-rich plasma (PRP) therapy is a novel procedure used to treat androgenetic alopecia (AGA). OBJECTIVE: Propose a mechanism of action of PRP therapy for AGA. METHODS AND MATERIALS: A thorough literature search including PRP research for AGA therapy as well as PRP research in other areas of medicine was conducted. RESULTS: A mechanistic model for the action of PRP on the hair follicle was created. CONCLUSION: Platelet-rich plasma therapy stimulates hair growth through the promotion of vascularization and angiogenesis, as well as encourages hair follicles to enter and extend the duration of the anagen phase of the growth cycle...
December 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27608205/double-blind-placebo-controlled-pilot-study-on-the-use-of-platelet-rich-plasma-in-women-with-female-androgenetic-alopecia
#14
RANDOMIZED CONTROLLED TRIAL
Carlos J Puig, Robert Reese, Michelle Peters
BACKGROUND: Platelet-rich plasma (PRP) has been suggested as a therapeutic intervention for female androgenetic alopecia. OBJECTIVE: To perform a pilot study on the effect of PRP scalp injections in women with female androgenetic alopecia. MATERIALS AND METHODS: This double-blind, multicenter, placebo-controlled study compared the effect of PRP with that of saline placebo as scalp injection. The endpoints were hair count and hair mass index (HMI), along with patient-opinion survey responses...
November 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27530764/micro-needling-depth-penetration-presence-of-pigment-particles-and-fluorescein-stained-platelets-clinical-usage-for-aesthetic-concerns
#15
Gordon H Sasaki
BACKGROUND: Aesthetic micro-needling (MN) has demonstrated skin permeability to cosmeceutical ingredients and platelet-rich plasma by creating reversible micro-channels in the skin. OBJECTIVES: The purposes of this study were to determine: (1) actual needle depth-penetrations by adjusting needle lengths in a disposable tip of an electric MN device; (2) time-dependent passage of pigment and platelets; and (3) safety and efficacy profiles in patients. METHODS: Excised micro-needled pre-auricular skin was used to determine actual depths of tissue penetration with six needle lengths, and the presence of massaged pigment particles (histological examination) and fluorescein-labeled platelets (confocal laser microscopy) in 1 mm depth micro-channels over an hour...
January 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/27300455/soft-tissue-augmentation-of-the-face-with-autologous-platelet-derived-growth-factors-and-tricalcium-phosphate-microtomography-evaluation-of-mice
#16
Antonio Scarano, Luca Valbonetti, Massimiliano Marchetti, Felice Lorusso, Maurizio Ceccarelli
BACKGROUND: The platelets used in oral, maxillofacial, and plastic surgery are generally grouped as concentrated platelet-rich plasma. The general principle of production consists of a centrifugation, making it possible to eliminate red blood cells, then acellular plasma, to preserve only the concentrated platelets. OBJECTIVE: The aim of the present study was that micro porous tricalcium phosphate (β-TCP) mixed with autologous platelet-derived growth factors could be an alternative to fat and hyaluronic acid which are widely used for oral and maxillofacial soft tissue augmentation...
July 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27234711/autologous-platelet-rich-plasma-for-the-treatment-of-pattern-hair-loss
#17
REVIEW
Babu Singh, Lynne J Goldberg
Platelet-rich plasma (PRP) is a solution derived from whole blood that is enriched in the platelet fraction. Platelets serve as a reservoir of growth factors and cytokines. When platelets are activated in vivo, signaling molecules are released into the immediate microenvironment and activate receptors for various pathways. Historically, PRP has been applied to wound beds to promote healing of complex wounds. Over the last decade, it has served as a valuable therapeutic tool in various specialties such as maxillofacial surgery, plastic surgery, orthopedics and sports medicine...
August 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27119924/collagen-and-fractionated-platelet-rich-plasma-scaffold-for-dermal-regeneration
#18
Matthew T Houdek, Cody C Wyles, Paul G Stalboerger, Andre Terzic, Atta Behfar, Steven L Moran
BACKGROUND: Current options for in vivo regeneration of dermal tissue remain limited. The purpose of this study was to engineer a unique scaffold capable of recruiting dermal stem cells from adjacent tissue, thus circumventing the need to seed the scaffolds with stem cells before implantation, leading to skin regeneration. METHODS: A hydrogel scaffold was created through combination of type I collagen along with fractionated platelet-rich plasma. This was compared to a control hydrogel consisting of type I collagen and fetal bovine serum...
May 2016: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27035501/randomized-placebo-controlled-double-blind-half-head-study-to-assess-the-efficacy-of-platelet-rich-plasma-on-the-treatment-of-androgenetic-alopecia
#19
RANDOMIZED CONTROLLED TRIAL
Rubina Alves, Ramon Grimalt
BACKGROUND: Platelet-rich plasma (PRP) was identified as having a beneficial effect in alopecia and has been postulated as a new therapy for androgenetic alopecia (AGA). OBJECTIVE: To assess the efficacy of PRP for the treatment of AGA. MATERIALS AND METHODS: This was a randomized, placebo-controlled, double-blind study in 25 patients with AGA. Platelet-rich plasma was injected in half-head and the other half-head with placebo. Each patient received a total of 3 treatments of PRP, 1 month apart...
April 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/26988129/platelet-rich-plasma-as-a-novel-treatment-for-lichen-planopillaris
#20
Željana Bolanča, Andy Goren, Biserka Getaldić-Švarc, Majda Vučić, Mirna Šitum
Treatment of lichen planopillaris (LPP) remains a significant challenge due to the irreversible damage inflicted on hair follicles combined with the low efficacy of existing treatments. We hypothesized that growth factors released by the use of platelet-rich plasma (PRP) may arrest the development of LPP. To test our hypothesis, we treated an LPP patient that has failed previous treatments with a new PRP regimen. Following PRP treatment and six months follow-up, the patient experienced complete regression of itching and hair shedding...
July 2016: Dermatologic Therapy
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