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https://www.readbyqxmd.com/read/27913962/bathing-and-associated-treatments-in-atopic-dermatitis
#1
REVIEW
Julia K Gittler, Jason F Wang, Seth J Orlow
Atopic dermatitis is one of the most common complaints presenting to dermatologists, and patients typically inquire as to appropriate bathing recommendations. Although many dermatologists, allergists, and primary-care practitioners provide explicit bathing instructions, recommendations regarding frequency of bathing, duration of bathing, and timing related to emollient and medication application relative to bathing vary widely. Conflicting and vague guidelines stem from knowledge related to the disparate effects of water on skin, as well as a dearth of studies, especially randomized controlled trials, evaluating the effects of water and bathing on the skin of patients with atopic dermatitis...
December 3, 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27904273/efficacy-and-safety-of-cream-containing-climbazole-piroctone-olamine-for-facial-seborrheic-dermatitis-a-single-center-open-label-split-face-clinical-study
#2
Hae Jeong Youn, Soo Young Kim, Minji Park, Won Hee Jung, Yang Won Lee, Yong Beom Choe, Kyu Joong Ahn
BACKGROUND: Seborrheic dermatitis (SD) is a multifactorial disease; Malassezia species play an important role in its pathogenesis. OBJECTIVE: We aimed to determine whether a cream containing climbazole/piroctone olamine (C/P cream), antifungal agents with expected efficacy against Malassezia species, could improve SD symptoms. METHODS: We instructed 24 patients with mild-to-moderate SD to apply the C/P cream and emollient cream on the right and left sides of the face, respectively, every morning and evening for 4 weeks...
December 2016: Annals of Dermatology
https://www.readbyqxmd.com/read/27904185/topical-therapy-in-atopic-dermatitis-in-children
#3
Dharshini Sathishkumar, Celia Moss
Atopic dermatitis (AD) is a common, chronic childhood skin disorder caused by complex genetic, immunological, and environmental interactions. It significantly impairs quality of life for both child and family. Treatment is complex and must be tailored to the individual taking into account personal, social, and emotional factors, as well as disease severity. This review covers the management of AD in children with topical treatments, focusing on: education and empowerment of patients and caregivers, avoidance of trigger factors, repair and maintenance of the skin barrier by correct use of emollients, control of inflammation with topical corticosteroids and calcineurin inhibitors, minimizing infection, and the use of bandages and body suits...
November 2016: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/27900750/-the-management-of-itching-in-burn-patients-during-the-rehabilitation-stage
#4
Shu-Fen Lo, Li-Jung Chang, Ting-Yuan Shiue, Ching-Yi Pan, Hui-Chuan Wu
Pruritus, a distressing symptom that affects burn patients, not only interferes with activities of daily living but also causes disturbed sleep, which has been associated with anxiety, depression, and other types of negative moods. Furthermore, the uncontrolled scratching that often accompanies pruritus causes tissue damage and may damage or destroy the skin graft. In this paper, the authors first describe the definition and mechanism of pruritus and next use itching-assessment tools to identify the triggering factors...
December 2016: Hu Li za Zhi the Journal of Nursing
https://www.readbyqxmd.com/read/27862339/novel-trpm8-agonist-cooling-compound-against-chronic-itch-results-from-a-randomized-double-blind-controlled-pilot-study-in-dry-skin
#5
S Ständer, M Augustin, D Roggenkamp, C Blome, T Heitkemper, A C Worthmann, G Neufang
BACKGROUND: Patients suffering from chronic pruritus (CP) due to dry skin with are often applying emollients containing menthol. However, topical menthol may be irritating and of weak potency in severe pruritus. Two TRPM8 agonists, (1R,2S,5R)-N-(2-(2-pyridinyl)ethyl)-2-ispropyl-5-methylcyclohexancarboxamide and menthoxypropan-ediol, combined as Cooling Compound (CC) have shown stronger activation of TRPM8 than menthol. OBJECTIVES: Objective of this study was to evaluate the efficacy and safety of CC in alleviating pruritus in patients with dry itchy skin...
November 11, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27855723/exceeding-the-recruitment-target-in-a-primary-care-paediatric-trial-an-evaluation-of-the-choice-of-moisturiser-for-eczema-treatment-comet-feasibility-randomised-controlled-trial
#6
Kingsley Powell, Victoria J Wilson, Niamh M Redmond, Daisy M Gaunt, Matthew J Ridd
BACKGROUND: Recruiting to target in randomised controlled trials of investigational medicinal products (CTIMPs) in primary care and paediatric populations is notoriously difficult. More evidence is needed for effective recruitment strategies in these settings. We report on the impact of different recruitment strategies used in the Choice of Moisturiser in Eczema Treatment (COMET) study - a feasibility trial comparing the effectiveness of four emollients for the treatment of childhood eczema - recruiting via general practitioner (GP) surgeries...
November 17, 2016: Trials
https://www.readbyqxmd.com/read/27853352/tear-lipid-layer-thickness-with-eye-drops-in-meibomian-gland-dysfunction
#7
Jennifer S Fogt, Matthew J Kowalski, P Ewen King-Smith, Alice T Epitropolous, Andrew J Hendershot, Carrie Lembach, John Paul Maszczak, Lisa A Jones-Jordan, Joseph T Barr
PURPOSE: The aim of this study was to evaluate the efficacy of a lipid containing emollient eye drop, Soothe XP, which was reformulated in 2014 with a more stable preservative and buffer system, compared to a control, non-emollient, eye drop (Systane Ultra) in improving lipid layer thickness (LLT) in subjects with dry eye due to meibomian gland dysfunction (MGD). PATIENTS AND METHODS: This prospective single-center, open-label, cross-over, examiner masked-study enrolled subjects aged 30-75 years with lipid-deficient dry eye and a clinical diagnosis of MGD as determined by a slit lamp examination, an evaluation of meibomian gland drop out with meibography, and a standard patient evaluation of eye dryness questionnaire of >5...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27852708/choice-of-moisturiser-for-eczema-treatment-comet-feasibility-study-of-a-randomised-controlled-parallel-group-trial-in-children-recruited-from-primary-care
#8
Matthew J Ridd, Kirsty Garfield, Daisy M Gaunt, Sandra Hollinghurst, Niamh M Redmond, Kingsley Powell, Victoria Wilson, Richard H Guy, Nicola Ball, Lindsay Shaw, Sarah Purdy, Chris Metcalfe
OBJECTIVES: To determine the feasibility of a randomised controlled trial of 'leave on' emollients for children with eczema. DESIGN: Single-centre, pragmatic, 4-arm, observer-blinded, parallel, randomised feasibility trial. SETTING: General practices in the UK. PARTICIPANTS: Children with eczema aged 1 month to <5 years. OUTCOME MEASURES: Primary outcome-proportion of parents who reported use of the allocated study emollient every day for the duration of follow-up (12 weeks)...
November 16, 2016: BMJ Open
https://www.readbyqxmd.com/read/27832218/guidelines-for-the-management-of-atopic-dermatitis-in-singapore
#9
Yong Kwang Tay, Yuin Chew Chan, Nisha Suyien Chandran, Madeline Sl Ho, Mark Ja Koh, Yen Loo Lim, Mark By Tang, Thamotharampillai Thirumoorthy
INTRODUCTION: Atopic dermatitis is a common, chronic pruritic condition affecting both children and adults, which has a negative impact on the quality of life. These guidelines were developed by an expert workgroup appointed by the Dermatological Society of Singapore, to provide doctors with information to assist in the management of their patients with atopic dermatitis. The workgroup members are experienced dermatologists with interest and expertise in eczemas. MATERIALS AND METHODS: Workgroup members arrived at a consensus on the topics to be included...
October 2016: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/27790690/measurements-of-structure-and-function-of-skin-emollient-effects-on-atopic-dermatitis
#10
C Edwards
No abstract text is available yet for this article.
November 2016: British Journal of Dermatology
https://www.readbyqxmd.com/read/27789051/-multiple-epidermolytic-acanthomas-of-the-genitalia
#11
I Moulonguet, M Serre, D Herskovitch
BACKGROUND: Epidermolytic hyperkeratosis presents a particular histological image common to several clinical pictures, including that of keratinopathic ichthyoses. It may also occur fortuitously in various tumoral and inflammatory lesions. It is the elementary histopathological lesion of epidermolytic acanthoma, which may either be single or multiple, and when it occurs in the genital area, is known as epidermolytic hyperkeratosis of the genitalia or multiple epidermolytic acanthoma of the genitalia...
October 24, 2016: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/27786594/worldwide-utilization-of-topical-remedies-in-treatment-of-psoriasis-a-systematic-review
#12
Mathias Tiedemann Svendsen, Janithika Jeyabalan, Klaus Ejner Andersen, Flemming Andersen, Helle Johannessen
OBJECTIVE: To review published literature describing the global use of topical antipsoriatics. MATERIALS AND METHODS: Search for English-language articles in Embase, Pubmed, PsycINFO and Cochrane Library. RESULTS: Fifty-four selected publications were found, describing psoriasis patients' use of topical antipsoriatics, using six different methods to collect data. The eight most frequently used topical treatments from the regions North/South America, North/Central/South Europe, Asia, Middle East and Australia were: corticosteroids used by 16-79%, complementary and alternative medicines used by 10-62%, phototherapies used by 0...
November 13, 2016: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/27746639/effects-of-emollient-containing-bee-venom-on-atopic-dermatitis-a-double-blinded-randomized-base-controlled-multicenter-study-of-136-patients
#13
Chung Eui You, Seok Hoon Moon, Kwang Hoon Lee, Kyu Han Kim, Chun Wook Park, Seong Joon Seo, Sang Hyun Cho
BACKGROUND: Atopic dermatitis (AD) is a common, complex disease that follows a chronic relapsing course and significantly affects the quality of life of patients. Skin barrier dysfunction and inflammatory processes induce and aggravate this skin condition. Proper use of an emollient for hydration is a keystone of AD treatment. Bee venom is known to have anti-inflammatory effects and has been widely used in traditional medicine to treat various inflammatory disorders. OBJECTIVE: To find out the beneficial effect of an emollient containing bee venom in the treatment of patients with AD...
October 2016: Annals of Dermatology
https://www.readbyqxmd.com/read/27676112/infant-skin-care-products-what-are-the-issues
#14
Joanne McManus Kuller
BACKGROUND: Infant skin is susceptible to dryness and irritation from external factors, including topical skin care products not formulated for the infant's skin. This may increase the risk of contact dermatitis. Parents frequently express concern regarding potential harm from ingredients in skin care products and seek information. This is complicated by several skin care myths. PURPOSE: The purpose of this literature review was to provide evidence-based information to educate parents on the use of products for preterm and term infants...
October 2016: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/27676111/extremely-preterm-infant-skin-care-a-transformation-of-practice-aimed-to-prevent-harm
#15
Deanna E Johnson
BACKGROUND: The skin of extremely preterm infants is underdeveloped and has poor barrier function. Skin maintenance interventions initiated in the neonatal intensive care unit (NICU) have immediate and lifelong implications when the potential for infection, allergen sensitization, and altered aesthetic outcomes are considered. In addition, the high-level medical needs of extremely preterm infants demand skin-level medical interventions that too often result in unintended skin harm. PURPOSE: We describe the use of a harm prevention, or consequence-centered, approach to skin care, which facilitates safer practice for extremely premature infants...
October 2016: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/27663925/acupuncture-as-a-complementary-method-of-traditional-psoriasis-treatment-myth-or-reality
#16
Darija Mahović, Fanika Mrsić
Dear Editor, the practitioners of traditional Chinese medicine described psoriasis some 2000 years ago (1). Psoriasis vulgaris is a common, chronic inflammatory skin disease whose worldwide prevalence ranges from 0.1-3% (2,3). Understanding the role of the immune system in psoriasis and the interplay between the innate and adaptive immune system has helped to manage this complex disease, which affects patients far beyond the skin changes themselves (2). In addition to the usual and widely accepted methods of treatment of psoriasis, including topical therapies, phototherapy, and conventional and biological systemic therapies, data can be found in the literature that suggest a favorable effect of acupuncture on the course of psoriasis (4,5)...
August 2016: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/27660478/preliminary-study-on-the-development-of-an-antistretch-marks-water-in-oil-cream-ultrasound-assessment-texture-analysis-and-sensory-analysis
#17
Cătălina Bogdan, Mirela L Moldovan, Ioana Manuela Man, Maria Crișan
PURPOSE: Striae distensae represent the result of the failure of the dermis to sustain intrinsic mechanical forces. Intensive moisturization of the lesions and use of emollient oils have been recommended for the prevention and treatment of striae distensae rubra. The aim of this research was to formulate an emollient water-in-oil cosmetic cream containing argan oil, which may be helpful in the prevention or early treatment of striae distensae. PATIENTS AND METHODS: Sensory evaluation of the consistency, firmness, adhesiveness, oiliness, spreadability, and rapidity of penetration into the skin was evaluated by 22 volunteers using 10-point scales for each descriptor...
2016: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/27639188/skin-absorption-through-atopic-dermatitis-skin-a-systematic-review
#18
A-S Halling-Overgaard, S Kezic, I Jakasa, K A Engebretsen, H Maibach, J P Thyssen
Patients with atopic dermatitis have skin barrier impairment in both lesional and non-lesional skin. They are typically exposed to emollients daily and topical anti-inflammatory medicaments intermittently, hereby increasing the risk of developing contact allergy and systemic exposed to chemicals ingredients found in these topical preparations. We systematically searched for studies that investigated skin absorption of various penetrants, including medicaments, in atopic dermatitis patients, but also animals with experimentally induced dermatitis...
September 17, 2016: British Journal of Dermatology
https://www.readbyqxmd.com/read/27608978/effect-of-provision-of-an-integrated-neonatal-survival-kit-and-early-cognitive-stimulation-package-by-community-health-workers-on-developmental-outcomes-of-infants-in-kwale-county-kenya-study-protocol-for-a-cluster-randomized-trial
#19
Lisa G Pell, Diego G Bassani, Lucy Nyaga, Isaac Njagi, Catherine Wanjiku, Thulasi Thiruchselvam, William Macharia, Ripudaman S Minhas, Patricia Kitsao-Wekulo, Amyn Lakhani, Zulfiqar A Bhutta, Robert Armstrong, Shaun K Morris
BACKGROUND: Each year, more than 200 million children under the age of 5 years, almost all in low- and middle-income countries (LMICs), fail to achieve their developmental potential. Risk factors for compromised development often coexist and include inadequate cognitive stimulation, poverty, nutritional deficiencies, infection and complications of being born low birthweight and/or premature. Moreover, many of these risk factors are closely associated with newborn morbidity and mortality...
2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27599609/pereskia-aculeata-miller-leaves-accelerate-excisional-wound-healing-in-mice
#20
Nícolas de Castro Campos Pinto, Puebla Cassini-Vieira, Elaine Maria de Souza-Fagundes, Lucíola Silva Barcelos, Maria Christina Marques Nogueira Castañon, Elita Scio
ETHNOPHARMACOLOGICAL RELEVANCE: The leaves of Pereskia aculeata Miller (Cactaceae), known as Barbados gooseberry, are used as emollients and to treat skin wounds and inflammatory process in Brazilian traditional medicine. AIM OF THE STUDY: This study investigated the topical wound healing activity of gels containing the methanol extract (ME) and hexane fraction (HF) of the leaves of this plant in a model of excisional wound healing in mice. MATERIAL AND METHODS: Mice were anesthetized and excisional skin wounds were performed using a circular metal punch of 5 mm diameter...
September 3, 2016: Journal of Ethnopharmacology
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