keyword
MENU ▼
Read by QxMD icon Read
search

Emollients

keyword
https://www.readbyqxmd.com/read/29762208/prevalence-of-atopic-dermatitis-and-pattern-of-drug-therapy-in-malaysian-children
#1
Yi-Yeong Goh, Fazlollah Keshavarzi, Yik Ling Chew
BACKGROUND: Atopic dermatitis (AD) is a chronic relapsing, noncontagious skin inflammation characterized by dry skin and itch. Mutation in filaggrin gene leads to defective skin barrier, allowing entry of allergen and eliciting immunological response. OBJECTIVES: The aims of this study were to investigate the prevalence of AD in Malaysian children and to understand the pattern of drug therapy. Such information could be useful to establish the relationship between ethnicity and family history of atopy and the development of associated signs and symptoms...
May 2018: Dermatitis
https://www.readbyqxmd.com/read/29761732/safety-assessment-of-polyether-lanolins-as-used-in-cosmetics
#2
Lillian C Becker, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler, James G Marks, Ronald C Shank, Thomas J Slaga, Paul W Snyder, F Alan Andersen, Bart Heldreth
The Cosmetic Ingredient Review (CIR) Expert Panel (Panel) assessed the safety of 39 polyether lanolin ingredients as used in cosmetics. These ingredients function mostly as hair conditioning agents, skin conditioning agent-emollients, and surfactant-emulsifying agents. The Panel reviewed available animal and clinical data, from previous CIR safety assessments of related ingredients and components. The similar structure, properties, functions, and uses of these ingredients enabled grouping them and using the available toxicological data to assess the safety of the entire group...
May 2018: International Journal of Toxicology
https://www.readbyqxmd.com/read/29760610/the-structure-and-function-of-the-epidermal-barrier-in-patients-with-atopic-dermatitis-treatment-options-part-two
#3
REVIEW
Jagoda Pelc, Magdalena Czarnecka-Operacz, Zygmunt Adamski
Atopic dermatitis (AD) is a chronic and recurrent disease induced by underlying defects of the epidermal barrier and immunological disorders, typical of atopic diseases. The genetic and immunological mechanisms (outlined in the previous paper) affecting the dysfunction of the barrier are intensified by environmental factors, e.g. airborne and food allergens, infections and stress. For this reason, proper skin care, which prevents further damage and restores the epidermal barrier is of such importance in the field of AD therapy...
April 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29750772/the-ins-and-outs-of-an-outside-in-view-of-allergies-atopic-dermatitis-and-allergy-prevention
#4
Marcus Shaker, Robert G P Murray, Julianne A Mann
PURPOSE OF REVIEW: The skin barrier is a dynamic innate immune organ. This review summarizes the current understanding of how deficiencies associated with atopic dermatitis invite other atopic disorders of the allergic march. RECENT FINDINGS: Atopic dermatitis is characterized by skin barrier defects (such as mutations in filaggrin), intrinsic proallergic T-helper cell 2 immune dysregulation, and skin microbiome alterations. These factors promote the development of food allergy and asthma...
May 9, 2018: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/29745452/efficacy-of-a-shower-cream-and-a-lotion-with-skin-identical-lipids-in-healthy-subjects-with-atopic-dry-skin
#5
Enzo Berardesca, Susan Mortillo, Norma Cameli, Marco Ardigo, Maria Mariano
BACKGROUND: Atopic dermatitis is a chronic, pruritic inflammatory skin disease that adversely affects quality of life. AIMS: The current study evaluates the efficacy of a shower cream and a lotion, each with skin-identical lipids and emollients, in the treatment of atopic dry skin of subjects with a history of atopic condition. METHODS: In all, 40 healthy females with clinically dry skin on the lower legs were enrolled in the study and underwent 4 weeks of daily use of the shower cream and 2 additional weeks of both the shower cream and the body lotion...
May 10, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29724863/new-evidence-challenges-use-of-bath-emollients-for-children-with-eczema
#6
EDITORIAL
Carsten Flohr, Amina Ahmed
No abstract text is available yet for this article.
May 3, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29724749/emollient-bath-additives-for-the-treatment-of-childhood-eczema-bathe-multicentre-pragmatic-parallel-group-randomised-controlled-trial-of-clinical-and-cost-effectiveness
#7
Miriam Santer, Matthew J Ridd, Nick A Francis, Beth Stuart, Kate Rumsby, Maria Chorozoglou, Taeko Becque, Amanda Roberts, Lyn Liddiard, Claire Nollett, Julie Hooper, Martina Prude, Wendy Wood, Kim S Thomas, Emma Thomas-Jones, Hywel C Williams, Paul Little
OBJECTIVES: To determine the clinical effectiveness and cost effectiveness of including emollient bath additives in the management of eczema in children. DESIGN: Pragmatic randomised open label superiority trial with two parallel groups. SETTING: 96 general practices in Wales and western and southern England. PARTICIPANTS: 483 children aged 1 to 11 years, fulfilling UK diagnostic criteria for atopic dermatitis. Children with very mild eczema and children who bathed less than once weekly were excluded...
May 3, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29723354/blocking-or-enhancing-effects-of-some-basic-emollients-in-uva-penetration
#8
Sevgi Akarsu, Emel Fetil, Ozlem Ozbagcivan, Ali Tahsin Gunes
BACKGROUND: Topical agents used in combination with phototherapy or photochemotherapy may have both blocking or enhancing effects in ultraviolet rays. OBJECTIVE: In this in vivo study, the effects of topical petrolatum, basis cream, glycerine, and olive oil on the transmission of ultraviolet A radiation were investigated. METHODS: A test was performed to determine the minimal phototoxic dose on 29 volunteers with only psoralen plus ultraviolet A (PUVA) and then the same test was repeated with white petrolatum, basis cream, glycerine, olive oil, and sunscreen (0...
March 2018: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29692852/emollient-treatment-of-atopic-dermatitis-latest-evidence-and-clinical-considerations
#9
REVIEW
Kam Lun Hon, Jeng Sum Charmaine Kung, Wing Gi Gigi Ng, Ting Fan Leung
Aim: To review current classes of emollients in the market, their clinical efficacy in atopic dermatitis (AD) and considerations for choice of an emollient. Methods: PubMed Clinical Queries under Clinical Study Categories (with Category limited to Therapy and Scope limited to Narrow) and Systematic Reviews were used as the search engine. Keywords of 'emollient or moisturizer' and 'atopic dermatitis' were used. Overview of findings: Using the keywords of 'emollient' and 'atopic dermatitis', there were 105 and 36 hits under Clinical Study Categories (with Category limited to Therapy and Scope limited to Narrow) and Systematic Reviews, respectively...
2018: Drugs in Context
https://www.readbyqxmd.com/read/29676818/new-insights-into-the-phenotypes-of-atopic-dermatitis-linked-with-allergies-and-asthma-in-children-an-overview
#10
F Amat, A Soria, P Tallon, M Bourgoin-Heck, N Lambert, A Deschildre, J Just
Atopic dermatitis (AD) is a complex disease with multiple causes and complex mechanistic pathways according to age of onset, severity of the illness, ethnic modifiers, response to therapy, and triggers. A group of difficult-to-manage patients characterized by early-onset AD and severe lifelong disease associated with allergic asthma and/or food allergy, has been identified. In this paper, we focus on these severe phenotypes, analyzing their links with other atopic comorbidities, and taking into account the results from recent cohort studies and meta-analyses...
April 20, 2018: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29676534/consensus-based-european-guidelines-for-treatment-of-atopic-eczema-atopic-dermatitis-in-adults-and-children-part-i
#11
A Wollenberg, S Barbarot, T Bieber, S Christen-Zaech, M Deleuran, A Fink-Wagner, U Gieler, G Girolomoni, S Lau, A Muraro, M Czarnecka-Operacz, T Schäfer, P Schmid-Grendelmeier, D Simon, Z Szalai, J C Szepietowski, A Taïeb, A Torrelo, T Werfel, J Ring
This guideline was developed as a joint interdisciplinary European project, including physicians from all relevant disciplines as well as patients. It is a consensus-based guideline, taking available evidence from other guidelines, systematic reviews and published studies into account. This first part of the guideline covers methods, patient perspective, general measures and avoidance strategies, basic emollient treatment and bathing, dietary intervention, topical anti-inflammatory therapy, phototherapy and antipruritic therapy, whereas the second part covers antimicrobial therapy, systemic treatment, allergen-specific immunotherapy, complementary medicine, psychosomatic counselling and educational interventions...
May 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29625204/bifurcation-analysis-of-a-mathematical-model-of-atopic-dermatitis-to-determine-patient-specific-effects-of-treatments-on-dynamic-phenotypes
#12
Gouhei Tanaka, Elisa Domínguez Hüttinger, Panayiotis Christodoulides, Kazuyuki Aihara, Reiko J Tanaka
Atopic dermatitis (AD) is a common inflammatory skin disease, whose incidence is currently increasing worldwide. AD has a complex etiology, involving genetic, environmental, immunological, and epidermal factors, and its pathogenic mechanisms have not yet been fully elucidated. Identification of AD risk factors and systematic understanding of their interactions are required for exploring effective prevention and treatment strategies for AD. We recently developed a mathematical model for AD pathogenesis to clarify mechanisms underlying AD onset and progression...
April 3, 2018: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/29610161/topical-hypochlorite-and-skin-acidification-improves-erythroderma-of-omenn-syndrome
#13
Margaret Wat, Arielle Olicker, Howard Meyerson, Susan Nedorost, Amy S Paller, Kevin Cooper
We describe a case of Omenn syndrome displaying exudative erythroderma and other characteristic features, including alopecia, absent B and naïve T cells, hyper immunoglobulin E levels, and eosinophilia. A pathogenic recombination-activating RAG1 homozygous genetic mutation confirmed the diagnosis. She required frequent antibiotics at both treatment and prophylactic doses, which alone did not control her erythroderma, but her high risk of infection precluded the use of systemic agents such as cyclosporine, which would further suppress her already severely compromised immune system...
April 2018: Pediatrics
https://www.readbyqxmd.com/read/29596731/prevention-and-treatment-of-diaper-dermatitis
#14
Ulrike Blume-Peytavi, Varvara Kanti
Diaper dermatitis (DD) is one of the most common skin conditions that infants suffer from and their caregivers manage in the first months post-birth. As such, questions of effective prevention and treatment of the condition often arise. Nonmedical skincare practices that support healthy skin barrier function can prevent DD manifestation or alleviate the condition in many cases. The usage of barrier emollients and improved diaper technology contributes to keeping moisture and irritants away from an infant's delicate skin...
March 2018: Pediatric Dermatology
https://www.readbyqxmd.com/read/29577991/the-effect-of-an-exfoliating-skincare-regimen-on-the-numbers-of-epithelial-squames-on-the-skin-of-operating-theatre-staff-studied-by-surface-microscopy
#15
A G Wernham, O L Cain, A M Thomas
BACKGROUND: The shedding of epithelial squames (skin scales) by staff in operating theatre air is an important source for deep infection following joint replacement surgery. This is a serious complication resulting in significant morbidity for the patient and substantial cost implications for healthcare systems. Much effort has been put into providing clean-air in operating theatres, yet little attention has been given to reducing the shedding of surface skin scales at source. AIM: Our aim was to develop a novel method for calculating surface skin scale density using surface microscopy and to use it to evaluate the effect of a skin care regimen on operating theatre staff...
March 22, 2018: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29576427/dermatologic-toxicity-occurring-during-anti-egfr-monoclonal-inhibitor-therapy-in-patients-with-metastatic-colorectal-cancer-a-systematic-review
#16
REVIEW
Mario E Lacouture, Milan Anadkat, Aminah Jatoi, Tamer Garawin, Chet Bohac, Edith Mitchell
Monoclonal antibody inhibitors of the epidermal growth factor receptor (EGFR) have been shown to improve outcomes for patients with metastatic colorectal cancer (mCRC) without RAS gene mutations. However, treatment with anti-EGFR agents can be associated with toxicities of the skin, nails, hair, and eyes. Because these dermatologic toxicities can result in treatment discontinuation and affect patient quality of life, their management is an important focus when administering anti-EGFR monoclonal antibodies. The present systematic review describes the current data reporting the nature and incidence of, and management and treatment options for, dermatologic toxicities occurring during anti-EGFR treatment of mCRC...
December 13, 2017: Clinical Colorectal Cancer
https://www.readbyqxmd.com/read/29571821/care-of-the-growth-restricted-newborn
#17
REVIEW
Bianca Carducci, Zulfiqar A Bhutta
With the first 1,000 days of life proving to be a critical window of opportunity for physical and cognitive growth and development, an optimal intrauterine environment is vital. If fetus needs are compromised prenatally, there is an increased risk of intrauterine growth restriction (IUGR), and infants being born premature, low birth weight (LBW), or small-for-gestational age (SGA). Specialized care of these high-risk infants is necessary in terms of preconception interventions, resuscitation, thermoregulation, nutritional support and kangaroo mother care...
February 26, 2018: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29533490/effects-of-a-protein-free-oat-plantlet-extract-on-microinflammation-and-skin-barrier-function-in-atopic-dermatitis-patients
#18
REVIEW
A Wollenberg, R Fölster-Holst, M Saint Aroman, F Sampogna, C Vestergaard
Atopic dermatitis (AD) is a common, highly pruritic, chronic inflammatory skin disease. Dysfunction of the epidermal barrier is witnessed by an increased transepidermal water loss in lesional and non-lesional AD skin. The inflammation in lesional AD skin is well characterized. Non-lesional skin of AD patients shows histological signs of a subclinical inflammation and a pro-inflammatory cytokine milieu. This microinflammation is present even in seemingly healed skin and must be taken into account regarding treatment of AD...
April 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29519170/dress-syndrome-a-detailed-insight
#19
Sapan Kumar Behera, Saibal Das, Alphienes Stanley Xavier, Sandhiya Selvarajan
Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a serious and potentially fatal adverse effect to therapeutic medications. The incidence of this condition varies among different ethnicities because of the difference in the genetic makeup. Though fever, rash and eosinophilia are essential features for the diagnosis of this syndrome, these vary from patient to patient along with the involvement of various organs such as liver, kidney, lungs, pancreas, etc. Some of the atypical features are dysphagia, agranulocytosis, and chylous ascites...
March 15, 2018: Hospital Practice (Minneapolis)
https://www.readbyqxmd.com/read/29514524/randomised-comparison-of-silicone-gel-and-onion-extract-gel-for-post-surgical-scars
#20
Taejong Song, Kye Hyun Kim, Kyo Won Lee
To compare the efficacy of silicone gel and onion extract gel on new surgical wounds, we performed a randomised controlled trial evaluating the appearance of the laparoscopic surgical scars of 60 subjects after 12 weeks of two times daily application of either silicone gel or onion extract gel. Objective scar assessment by the Vancouver Scar Scale (VSS) and the Image Panel Scale (IPS) and subjective scar assessment by the Body Image Scale (BIS) and Cosmetic Scale (CS) were performed after 12 weeks of treatment...
March 7, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
keyword
keyword
85340
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"