Read by QxMD icon Read

Patent ductus arteriosus

Abdulraouf M Z Jijeh, Muna Ismail, Aisha Al-Bahanta, Ahmed Alomrani, Omar Tamimi
Background: Congenital aortic stenosis (AS) is a rare disease. Treatment options for newborns are challenging. Newborns may have higher reintervention rate and mortality. Objectives: The study aimed to identify the factors predictive of reintervention following balloon aortic valvuloplasty (BAV) for AS during infancy. Methods: Retrospectively, between 2001 and 2016, echocardiography (echo) and cardiac catheterization data for infants with AS were analyzed, including follow-ups and reinterventions...
May 2018: Annals of Pediatric Cardiology
Shivanand Gangahanumaiah, Bronwyn C Scarr, Mark R Buckland, David V Pilcher, Miranda A Paraskeva, David C McGiffin
A 27-year-old female with Eisenmenger's syndrome underwent closure of a patent ductus arteriosus, closure of a perimembranous ventricular septal defect and mid muscular defect and bilateral lung transplantation. Her immediate postoperative course was complicated by severe right ventricular outflow tract (RVOT) obstruction resulting in hemodynamic collapse, a condition described as suicide right ventricle. The patient was placed on central Veno-Arterial Extra-Corporeal Membrane Oxygenation as a bridge to the relief of RVOT obstruction which included a right ventricular outflow muscle resection and a right ventricle outflow tract patch...
June 19, 2018: Journal of Cardiac Surgery
Brian A Scansen
There remain areas of uncertainty in optimal technique, preferred candidates, and expected outcome for small animal patients undergoing cardiac intervention. This article highlights issues within interventional cardiology that are in need of study and offers the author's opinion and experience on topics such as variants of pulmonary valve anatomy and alternatives to conventional balloon dilation for pulmonary valve stenosis, patient selection for cutting or high-pressure balloon dilation of aortic valvar or subaortic stenosis, occlusion of patent ductus arteriosus in very small dogs, ductal stenting in conditions with reduced pulmonary blood flow, and alternative considerations for vascular access and closure...
June 16, 2018: Veterinary Clinics of North America. Small Animal Practice
Varangthip Khuwuthyakorn, Chuleeporn Jatuwattana, Suchaya Silvilairat, Watcharee Tantiprapha
Background In low- and middle-income countries (LMIC), haemodynamically significant patent ductus arteriosus (hsPDA) is treated with oral indomethacin (IDC) and ibuprofen (IB) instead of intravenous formulations. No significant differences in efficacy have been reported. However, previous studies had small numbers of VLBW infants (<1500 g). Objective To evaluate the efficacy of oral IDC and IB for closing PDA in VLBW infants with a gestational age of 24-32 weeks. Methods This randomised controlled study enrolled 32 infants with hsPDA for treatment with either three doses of oral IDC or oral IB...
June 18, 2018: Paediatrics and International Child Health
Leeann R Pavlek, Jonathan L Slaughter, Darren P Berman, Carl H Backes
Risks associated with drug therapy and surgical ligation have led health care providers to consider alternative strategies for patent ductus arteriosus (PDA) closure. Catheter-based PDA closure is the procedure of choice for ductal closure in adults, children, and infants ≥6kg. Given evidence among older counterparts, interest in catheter-based closure of the PDA in lower weight (<6kg) infants is growing. Among these smaller infants, the goals of this review are to: (1) provide an overview of the procedure; (2) review the types of PDA closure devices; (3) review the technical success (feasibility); (4) review the risks (safety profile); (5) discuss the quality of evidence on procedural efficacy; (6) consider areas for future research...
June 13, 2018: Seminars in Perinatology
Ting Chen, Li Qiu, Lin Zhong, Qingfen Tao, Hanmin Liu, Lina Chen
There is a lack of data describing the role of flexible bronchoscopy (FB) in evaluating pulmonary diseases in children with congenital cardiovascular abnormalities in China. Determining whether those children suffer from respiratory complications may be useful for future preoperative planning and family counseling. The present study aimed to investigate the features and FB-associated findings with respect to pulmonary diseases in children with congenital cardiovascular abnormalities. The role of FB in guiding the treatment and safety of procedures was also evaluated...
June 2018: Experimental and Therapeutic Medicine
Xing-Wang Zhu, Yuan Shi, Li-Ping Shi, Ling Liu, Jiang Xue, Rangasamy Ramanathan
BACKGROUND: Invasive mechanical ventilation (IMV) is associated with the development of adverse pulmonary and non-pulmonary outcomes in very premature infants. Various modes of non-invasive respiratory support are increasingly being used to decrease the incidence of bronchopulmonary dysplasia. The aim of this trial is to compare the effect of non-invasive high-frequency oscillatory ventilation (NHFOV) and nasal continuous positive airway pressure (NCPAP) in preterm infants with respiratory distress syndrome (RDS) as a primary non-invasive ventilation support mode...
June 14, 2018: Trials
Syed M Rehman, Antonio Ravaglioli, Kanchana Singappuli, Kevin Roman, James Gnanapragasam, Duminda Samarasinghe, Nicola Viola
Single-stage repair of complex cardiac abnormalities in high-risk neonates presents formidable challenges. The majority of hybrid strategies involving bilateral pulmonary artery banding (bPAB) with or without patent ductus arteriosus (PDA) stenting is described in the setting of hypoplastic left heart syndrome. We present a series of cases describing two-stage repair with initial palliative hybrid procedures involving bPAB with or without PDA stenting. This allows weight gain and stabilization of circulation before complete repair, provides good results, and may overcome risk factors associated with single-stage repair in neonates...
June 12, 2018: Journal of Cardiac Surgery
HongChang Guo, Yang Wang, Wenhui Wu, Yongqiang Lai
Patients with patent ductus arteriosus (PDA) are usually detected and treated during childhood, however, some are not detected until adulthood. In addition, heart failure, severe pulmonary hypertension, and calcification of the ductus may also exist. Transcatheter occlusion has become a widely used technique for the closure of small to moderate sized PDAs since Cambier first reported use of Gianturco coils for transcatheter closure of PDA in 1992 [Cambier 1992]. In the case studies reported here, the one-stage hybrid procedure for PDA combined with other cardiac anomalies in adults was applied with satisfactory results...
May 16, 2018: Heart Surgery Forum
Yuki Nakamura, Bijoy Thattaliyath, Marco Ricci
A combination of hypoplasia of the left side of the heart, a hypoplastic aortic arch, a large patent ductus arteriosus, and valvular pulmonary stenosis is very rare. The severity of the valvular pulmonary stenosis in this setting is difficult to judge preoperatively. Here, we describe a newborn with borderline hypoplasia of the left side of the heart, a hypoplastic aortic arch, a large patent ductus arteriosus, and valvular pulmonary stenosis, who underwent the Norwood procedure successfully. The purpose of this report is to share the perioperative course of the patient and our decision-making process that was not straightforward...
June 8, 2018: Annals of Thoracic Surgery
Mohit Pahuja, Aiden Abidov
Cardiac MRI is a complementary and confirmatory modality to a clinical echocardiography in diagnosing patients with complex adult congenital heart disease, especially in presence of great vessel abnormalities. We present a unique case of a patient with pulmonary hypertension (PH), severe right ventricular hypertrophy, Gerbode defect, and a large patent ductus arteriosus (PDA). The diagnosis of PDA was not visualized on prior serial echocardiograms and discovered on a comprehensive cardiac MRI/Chest MR angiogram...
June 10, 2018: Echocardiography
Jennifer Shepherd, Kai-Hsiang Hsu, Shahab Noori
Although patent ductus arteriosus is essential in fetal life, interventions to close or minimize the adverse hemodynamic effects associated with the left-to-right shunt are often needed after birth, especially in extremely premature infants. However, there are clinical conditions where maintaining patency of the ductus is essential for survival. In this article we discuss use of prostaglandin E1 in the management of congenital heart defects, pulmonary hypertension and left ventricular failure in early neonatal period...
June 1, 2018: Seminars in Fetal & Neonatal Medicine
Naveen Garg, Deep Chandh Raja, Roopali Khanna, Sudeep Kumar
Abnormally oriented patent ductus arteriosus is expected in adults, which can lead to difficulties while attempting a device closure. Alternate angiographic views like the "right anterior oblique view," "retrograde approach" and in rare cases, as elicited in the following case scenario, special catheters like the "Tiger® catheter" can aid in crossing the lesion and completion of the procedure successfully.
January 2018: Heart Views: the Official Journal of the Gulf Heart Association
Pierre-Emmanuel Séguéla, Julie Thomas-Chabaneix, Zakaria Jalal, François Roubertie, Léa Faydi, Jean-Baptiste Mouton, Eric Dumas-de-la-Roque, Olivier Tandonnet, Xavier Pillois, Jean-Benoit Thambo, Xavier Iriart
BACKGROUND: Coarctation of the aorta (CoA) is still challenging to diagnose in neonates with patent ductus arteriosus (PDA). Speckle tracking echocardiography allows reliable analysis of myocardial deformation in newborns and seems to provide important insides into regional changes in patients with left ventricular (LV) outflow tract obstruction. AIMS: To assess the interest of LV global longitudinal strain (GLS) measurement for predicting CoA in neonates with PDA and prenatal suspicion...
June 3, 2018: Archives of Cardiovascular Diseases
Jane E Stremming, Clyde J Wright, Laura D Brown
This study was a prospective, randomized trial comparing paracetamol to indomethacin and ibuprofen for closing a hemodynamically significant patent ductus arteriosus (hs-PDA) in premature neonates (<28 weeks GA or <1500 grams). Currently available treatments to close the PDA include indomethacin and ibuprofen, but these treatments have been associated with transient reduction in kidney function (1,2), and they are contraindicated in patients with active bleeding or renal dysfunction. Surgical ligation of the PDA has been associated with worse neurodevelopmental outcomes and BPD (3), although there may be no difference in outcomes after correcting for perinatal confounders (4)...
June 6, 2018: Acta Paediatrica
Dimple Goel, Pankaj Gupta, Stephen Cooper, Jan Klimek
AIM: Cardiorespiratory physiology plays an important role in neonatal care with increasing utility of point of care ultrasound. This review is to bring to light the importance of systemic to pulmonary collaterals (SPCs) in the preterm population without congenital heart disease (CHD) and provide a useful diagnostic tool to the neonatologist performing a cardiac ultrasound. METHODS: Medline, PubMed, EMBASE, and the internet were searched up to November 2017 for papers in English which included SPCs in preterm infants without CHD...
June 5, 2018: Acta Paediatrica
Yogen Singh, Anup Katheria, Cecile Tissot
The role of functional echocardiography in neonatal intensive care unit is rapidly evolving, and increasingly neonatologists are using it in making clinical decisions in sick infants. Functional echocardiography can provide a direct assessment of hemodynamics on bedside, and may be considered as an extension of the clinical examination to evaluate cardiovascular wellbeing in the critically-ill infant. The physiological information may be used in targeting specific intervention based upon the underlying pathophysiology...
May 15, 2018: Indian Pediatrics
V Katheria, D M Poeltler, M Brown, K O Hassen, D Patel, W Rich, N N Finer, A C Katheria
BACKGROUND: The optimal thresholds for identification of preterm infants at greatest risk for adverse sequelae related to patent ductus arteriosus have not been well delineated. Our aim was to determine hemodynamic parameters in the first 24 hours using continuous non-invasive vital and structural measurements to predict which infants required PDA treatment in our institution. METHODS: Retrospective secondary analysis of data from infants born 23 to 32 weeks gestational age with cardiac output and stroke volume via electrical cardiometry, cerebral tissue oximetry measurements, mean arterial blood pressure (BP), heart rate, and oxygen saturation and functional echocardiography results at 12 hours of life were recorded when available (93 percent of subjects)...
May 23, 2018: Journal of Neonatal-perinatal Medicine
Gustavo Rocha, Filipa Flor de Lima, Ana Paula Machado, Hercília Guimarães
INTRODUCTION: It is not known whether very preterm infants born to preeclamptic women have worse outcomes than those delivered preterm for other causes. OBJECTIVE: We assessed the association between preeclampsia (PE) and the neonatal morbidity and mortality of very preterm infants. METHODS: Over 2015 and 2016, 11 collaborating Portuguese level III NICUs prospectively enrolled a cohort of mothers with or without PE who delivered liveborn premature infants between 24 and 30 completed weeks of gestation...
May 29, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
B Ezenwa, E Pena, A Schlegel, R Bapat, E G Shepherd, L D Nelin
AIM: To determine if a decrease in patent ductus arteriosus (PDA) treatment or ligation in extremely preterm infants was associated with changes in rates of mortality and/or morbidities. METHODS: Observational study on extremely preterm infants admitted from 2008 to 2015. The small baby guidelines do not mandate ligation, however, in late 2010 the guidelines were amended based on new literature suggested that ligation may increase rates of morbidities. RESULTS: There were 717 extremely preterm infants admitted during the study period...
May 28, 2018: Acta Paediatrica
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"