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Patent ductus arteriosus

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https://www.readbyqxmd.com/read/29453434/post-ligation-cardiac-syndrome-is-associated-with-increased-morbidity-in-preterm-infants
#1
Timothy J B Ulrich, Taylor P Hansen, Kimberly J Reid, Michael A Bingler, Steven L Olsen
OBJECTIVE: The influence of post-ligation cardiac syndrome (PLCS), a complication of patent ductus arteriosus (PDA) ligations, on neonatal outcomes is unknown. The purpose of this study was to determine the risks of PLCS on severe pulmonary morbidity and severe retinopathy of prematurity (ROP). STUDY DESIGN: Retrospective cohort study of infants who underwent a PDA ligation between 2006 and 2015. Data were collected on patients with and without PLCS. The primary outcome was the difference in severe bronchopulmonary dysplasia (BPD) between groups...
February 16, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29452581/prospective-observational-study-on-assessing-the-hemodynamic-relevance-of-patent-ductus-arteriosus-with-frequency-domain-near-infrared-spectroscopy
#2
Christoph E Schwarz, Antonio Preusche, Martin Wolf, Christian F Poets, Axel R Franz
BACKGROUND: What constitutes a hemodynamically relevant patent ductus arteriosus (hrPDA) in preterm infants is unclear. Different clinical and echocardiographic parameters are used, but a gold standard definition is lacking. Our objective was to evaluate associations between regional cerebral tissue oxygen saturation (rcStO 2 ), fraction of tissue oxygen extraction (rcFtO 2 E) measured by frequency domain near-infrared spectroscopy (fd-NIRS) and their correlation to echocardiographic, Doppler-ultrasound, and clinical parameters in preterm infants with and without a hrPDA...
February 16, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29450194/avoiding-arterial-hypotension-in-preterm-neonates-ahip-a-single-center-randomised-controlled-study-investigating-simultaneous-near-infrared-spectroscopy-measurements-of-cerebral-and-peripheral-regional-tissue-oxygenation-and-dedicated-interventions
#3
Gerhard Pichler, Nina Höller, Nariae Baik-Schneditz, Bernhard Schwaberger, Lukas Mileder, Jasmin Stadler, Alexander Avian, Jasmin Pansy, Berndt Urlesberger
Introduction: Up to 50% of preterm infants admitted to intensive care units require cardiocirculatory support. The aim of the present study was to assess whether simultaneous monitoring of cerebral tissue oxygenation index (cTOI) and peripheral tissue oxygenation index (pTOI) using near-infrared spectroscopy (NIRS) in combination with dedicated intervention guidelines may help avoiding arterial hypotension and catecholamine administration in preterm neonates. Study design: Preterm neonates <37 weeks of gestation were included in a single center randomized controlled study...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29449050/a-novel-truncating-mutation-in-flna-causes-periventricular-nodular-heterotopia-ehlers-danlos-like-collagenopathy-and-macrothrombocytopenia
#4
Daisuke Ieda, Ikumi Hori, Yuji Nakamura, Hironori Ohshita, Yutaka Negishi, Tsutomu Shinohara, Ayako Hattori, Takenori Kato, Sachiko Inukai, Katsumasa Kitamura, Tomoki Kawai, Osamu Ohara, Shinji Kunishima, Shinji Saitoh
INTRODUCTION: Filamin A (FLNA) is located in Xq28, and encodes the actin binding protein, filamin A. A mutation in FLNA is the most common cause of periventricular nodular heterotopia (PVNH), but a clear phenotype-genotype correlation has not been established. Indeed, some patients with a FLNA mutation have recently been shown to additionally have Ehlers-Danlos-like collagenopathy or macrothrombocytopenia. In an attempt to establish a clearer correlation between clinical symptoms and genotype, we have investigated a phenotype that involves thrombocytopenia in a patient with a truncation of the FLNA gene...
February 12, 2018: Brain & Development
https://www.readbyqxmd.com/read/29445470/emergency-transcatheter-closure-of-a-stented-pda-in-a-patient-with-pulmonary-atresia-and-intact-ventricular-septum-be-ready-for-the-unexpected
#5
Alessia Faccini, Gianfranco Butera
Patients with congenital heart disease and duct-dependent pulmonary circulation can undergo stenting of the patent ductus arteriosus (PDA). This case shows that, due to the physiological changes occurring after stent implantation, sometimes it is necessary to close the stented PDA rather than to redilate it.
February 2018: Clinical Case Reports
https://www.readbyqxmd.com/read/29444139/post-discharge-body-weight-and-neurodevelopmental-outcomes-among-very-low-birth-weight-infants-in-taiwan-a-nationwide-cohort-study
#6
Chung-Ting Hsu, Chao-Huei Chen, Ming-Chih Lin, Teh-Ming Wang, Ya-Chi Hsu
BACKGROUND: Premature infants are at high risk for developmental delay and cognitive dysfunction. Besides medical conditions, growth restriction is regarded as an important risk factor for cognitive and neurodevelopmental dysfunction throughout childhood and adolescence and even into adulthood. In this study, we analyzed the relationship between post-discharge body weight and psychomotor development using a nationwide dataset. MATERIALS AND METHODS: This was a nationwide cohort study conducted in Taiwan...
2018: PloS One
https://www.readbyqxmd.com/read/29440844/cost-effectiveness-analysis-of-devices-for-closure-of-patent-ductus-arteriosus
#7
K M Krishnamoorthy, Arun Gopalakrishnan
No abstract text is available yet for this article.
January 2018: Annals of Pediatric Cardiology
https://www.readbyqxmd.com/read/29434740/a-pilot-study-of-a-cardiovascular-virtual-endoscopy-system-based-on-multi-detector-computed-tomography-in-diagnosing-tetralogy-of-fallot-in-pediatric-patients
#8
Li-Ping Yao, Li Zhang, Ju Mei, Fang-Bao Ding, Hui-Ming Li, Ming Ding, Xin Yang, Xiao-Ming Li, Kun Sun
The present study aimed to investigate the capabilities of the cardiovascular virtual endoscopy (VE) system in diagnosing tetralogy of Fallot (TOF) and performing measurements. A total of 37 patients underwent two-dimensional echocardiography (2-DE) and multi-detector computed tomography (MDCT) examinations. The obtained MDCT images were applied to a cardiovascular VE system. Diagnostic time by VE was first studied and compared with MDCT. Subsequently, with surgical findings as the ground truth, the capabilities of VE, 2-DE and MDCT in diagnosing TOF and its complications were investigated...
February 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29432197/echocardiographic-assessment-of-left-to-right-shunts-atrial-septal-defect-ventricular-septal-defect-atrioventricular-septal-defect-patent-arterial-duct
#9
REVIEW
Antigoni Deri, Kate English
This review article will guide the reader through the basics of echocardiographic assessment of congenital left to right shunts in both paediatric and adult age groups. After reading this article the reader will understand the pathology and clinical presentation of atrial septal defects (ASDs), ventricular septal defects (VSDs), atrioventricular septal defects (AVSDs) and patent ductus arteriosus (PDA). In times gone by the stethoscope was the primary diagnostic tool used to diagnose these lesions, but in today's clinicians those skills have been usurped by the superiority of the trans-thoracic echo probe...
February 5, 2018: Echo Research and Practice
https://www.readbyqxmd.com/read/29422111/an-unusual-case-of-interrupted-cervical-aortic-arch-associated-with-long-segment-coarctation-of-the-descending-thoracic-aorta
#10
Mousam Dey, Naveen Garg, Sunil Kumar
Interrupted aortic arch is a rare congenital anomaly in newborns and infants and is commonly associated with other cardiovascular anomalies. Here, we report an unusual case of type A interrupted cervical aortic arch associated with long segment coarctation of the descending thoracic aorta. Patent ductus arteriosus reconstituted the descending thoracic aorta. Proximal segments of the left common carotid and left subclavian arteries were atretic. Echocardiography-gated multidetector CT angiography not only identified the type of aortic arch interruption in the neonate but also delineated the exact anatomical details...
February 9, 2018: Cardiology in the Young
https://www.readbyqxmd.com/read/29421004/variation-in-practice-patterns-in-device-closure-of-atrial-septal-defects-and-patent-ductus-arteriosus-an-analysis-of-data-from-the-improving-pediatric-and-adult-congenital-treatment-impact-registry
#11
Michael L O'Byrne, Kevin F Kennedy, Jonathan J Rome, Andrew C Glatz
Practice variation is a potentially important measure of healthcare quality. The IMPACT registry provides a representative national sample with which to study practice variation in trans-catheter interventions for congenital heart disease. METHODS: We studied cases for closure of atrial septal defect (ASD) and patent ductus arteriosus (PDA) in IMPACT between January 1, 2011, and September 30, 2015, using hierarchical multivariate models studying (1) the distribution of indications for closure and (2) in patients whose indication for closure was left (LVVO) or right ventricular volume overload (RVVO), the factors influencing probability of closure of a small defect (either in size or in terms of the magnitude of shunt)...
February 2018: American Heart Journal
https://www.readbyqxmd.com/read/29411259/intravitreal-aflibercept-for-the-treatment-of-choroidal-neovascularization-associated-with-rubella-retinopathy
#12
Hasan Kiziltoprak, Esat Yetkin, Kemal Tekin, Mustafa Koc, İrfan Akalin, Mehmet Yasin Teke
PURPOSE: To report a case of choroidal neovascularization (CNV) associated with rubella retinopathy (RR) treated with intravitreal aflibercept. CASE PRESENTATION: A 15-year-old girl presented a complaint of visual decrease in her left eye. She had a history of hearing decrease since she was 1 year old in addition to patent ductus arteriosus. On ocular examination, the best corrected visual acuity (BCVA) was 20/20 in the right eye and 20/400 in the left eye. Dilated fundus examinations revealed a classic salt-and-pepper appearance in both eyes and a whitish subretinal lesion with retinal hemorrhages in the left macula...
February 6, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29409564/post-patent-ductus-arteriosus-ligation-syndrome-with-hypertension-and-masking-of-renal-artery-stenosis-in-an-infant
#13
Erica E ElSeed Peterson, Daniel Mauriello
Post-patent ductus arteriosus ligation syndrome is common, but rarely has hypertension been described following ductal ligation with an unclear mechanism. We report a case of an infant who exhibited features of post-patent ductus arteriosus ligation syndrome and hypertension, but was found to have bilateral renal artery stenosis. Increased systemic vascular resistance can be masked by the parallel circuit physiology of a patent ductus arteriosus.
February 7, 2018: Cardiology in the Young
https://www.readbyqxmd.com/read/29399946/techniques-for-trans-catheter-retrieval-of-embolized-nit-occlud%C3%A2-pda-r-and-asd-r-devices
#14
Sanjay Sinha, Daniel Levi, Alejandro Peirone, Carlos Pedra
BACKGROUND: Nit-Occlud® (atrial septal defect) ASD-R and (patent ductus arteriosus) PDA-R devices are used outside the United States for percutaneous closure of the patent ductus arteriosus and atrial septal defects. When embolization occurs, these devices have been difficult to retrieve. METHODS: Bench simulations of retrieval of PDA-R and ASD-R devices were performed in a vascular model. Retrieval of each device was attempted using snare techniques or with bioptome forceps with a range of devices...
February 5, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29392321/retinopathy-of-prematurity-among-very-low-birth-weight-infants-in-china-incidence-and-perinatal-risk-factors
#15
Tian Wu, Li Zhang, Yu Tong, Yi Qu, Bin Xia, Dezhi Mu
Purpose: Retinopathy of prematurity (ROP) is the leading cause of blindness in children worldwide. This study aimed to determine the incidence and perinatal risk factors for ROP in very low-birth-weight (VLBW) Chinese infants. Methods: A retrospective study of the medical records of 504 VLBW infants screened for ROP from 2012 to 2015 was performed in West China Second University Hospital. VLBW infants were examined according to the Royal College of Ophthalmologists ROP guideline and retinopathy was graded following the International Classification of ROP...
February 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29377085/modified-rib-pivot-lateral-thoracotomy-a-case-series
#16
C Appelgrein, G Hosgood
OBJECTIVE: To describe a modified rib pivot thoracotomy and its clinical application in client-owned dogs and cats. STUDY DESIGN: Case series of 24 dogs and 1 cat requiring a thoracotomy. METHODS: A lateral thoracic incision over the required thoracic segment was made. The latissimus dorsi muscle was reflected dorsally. The predetermined rib was identified and the periosteum overlying the rib was elevated circumferentially, avoiding the intercostal neurovascular structures...
January 2018: Australian Veterinary Journal
https://www.readbyqxmd.com/read/29372379/effect-on-cerebral-oxygenation-of-paracetamol-for-patent-ductus-arteriosus-in-preterm-infants
#17
Carlo Dani, Chiara Poggi, Ilaria Cianchi, Iuri Corsini, Venturella Vangi, Simone Pratesi
Paracetamol seems to have similar success rates compared with indomethacin and ibuprofen in closing patent ductus arteriosus (PDA) in preterm infants, but with a better safety profile. The aim of our study was to evaluate the possible effects of paracetamol on cerebral oxygenation and cerebral blood flow velocity (CBFV). Infants with gestational age < 32 weeks with hemodynamically significant PDA (hsPDA) were prospectively studied by near infrared spectroscopy (NIRS) after the first dose of paracetamol (15 mg/kg) or ibuprofen (10 mg/kg)...
January 25, 2018: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29367269/percutaneous-occlusion-of-patent-ductus-arteriosus-for-an-elderly-patient-with-refractory-congestive-heart-failure
#18
Satoshi Shoji, Hideaki Kanazawa, Ryo Yanagisawa, Makoto Tanaka, Ryoma Fukuoka, Keitaro Akita, Mai Kimura, Takahide Arai, Takashi Kawakami, Kentaro Hayashida, Shinsuke Yuasa, Hikaru Tsuruta, Yuji Itabashi, Mitsushige Murata, Takahiko Nishiyama, Takashi Kohno, Yuichiro Maekawa, Keiichi Fukuda
No abstract text is available yet for this article.
February 2018: Circulation. Heart Failure
https://www.readbyqxmd.com/read/29353231/the-preterm-heart-in-childhood-left-ventricular-structure-geometry-and-function-assessed-by-echocardiography-in-6-year-old-survivors-of-periviable-births
#19
Lilly-Ann Mohlkert, Jenny Hallberg, Olof Broberg, Annika Rydberg, Cecilia Pegelow Halvorsen, Petru Liuba, Vineta Fellman, Magnus Domellöf, Gunnar Sjöberg, Mikael Norman
BACKGROUND: Preterm birth has been associated with increased risk of cardiovascular morbidity in adult life. We evaluated whether preterm birth is associated with deviating cardiac structure and function before school start. METHODS AND RESULTS: In total, 176 children aged 6 years and born extremely preterm (EXPT; gestational age of 22-26 weeks) and 134 children born at term (control [CTRL]) were studied. We used echocardiography to assess left heart dimensions, geometry, and functions...
January 20, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29352349/factors-affecting-n-terminal-pro-b-type-natriuretic-peptide-levels-in-preterm-infants-and-use-in-determination-of-haemodynamic-significance-of-patent-ductus-arteriosus
#20
Sarah Louise Harris, Kiran More, Bronwyn Dixon, Richard Troughton, Chris Pemberton, John Horwood, Nicola Ellis, Nicola Austin
This study aimed to investigate factors affecting N-terminal pro-B-type natriuretic peptide (NTproBNP) in preterm infants and the ability of NTproBNP to predict haemodynamically significant patent ductus arteriosus (HsPDA). Prospective cohort study of 51 infants < 30 weeks gestation. Blood NTproBNP and heart ultrasound were performed on day of life 3, 10, 28 and 36 weeks corrected age. NTproBNP levels analysed for prediction of HsPDA. The effect of gestational age, ventilation, hypoxia, bronchopulmonary dysplasia (BPD), creatinine and haemoglobin levels on NTproBNP levels were investigated...
January 19, 2018: European Journal of Pediatrics
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