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Hamid Galehdari, Samira Negahdari, Mahnaz Kesmati, Anahita Rezaie, Gholamreza Shariati
BACKGROUND: Wound healing is often impaired in diabetic animals and humans. Matrix metalloproteases act as pro-inflammatory agents in physiological wound healing pathways by stimulating cytokines including the interleukins, IL6, IL1A and IL1B, and the tumor necrosis factor and transforming growth factor beta1. Botanicals are traditionally used to assist healing of different types of wounds, because they produce fewer side effects. Our specific aim here was to develop a plant-based recipe supporting effective wound healing in diabetic animals...
October 6, 2016: BMC Complementary and Alternative Medicine
E S Rizzi, D M Dourado, R Matias, J A I Muller, J F Guilhermino, A T G Guerrero, D L Moreira, B A K Silva, M Barbosa-Ferreira
Impaired wound healing represents a serious complication in some pathologies and the use of plant extracts has proved to improve tissue repair. The objectives of this study were to evaluate the healing potential of the ointment of Sebastiana hispida compared with Aluminum-Gallium Indium-Phosphide Laser (InGaAlP) in surgically induced wounds in rats and to perform the phytochemical analysis. The phytochemical analysis was performed in the classic way and also by HPLC. A controlled study was developed with 80 rats (200-250 g) in which a linear excision was performed in the dorsal region after shaving, measuring 2 cm × 1 cm (epidermis and dermis) exposing the muscle fascia...
October 3, 2016: Brazilian Journal of Biology, Revista Brasleira de Biologia
Salih Levent Cinar, Demet Kartal, Ayse Kacar Bayram, Mehmet Canpolat, Murat Borlu, Ayten Ferahbas, Hüseyin Per
BACKGROUND: The skin is one of the most affected organs in tuberous sclerosis complex and angiofibromas are seen in almost 80% of such patients. These benign tumors impose a great psycho-social burden on patients. OBJECTIVE: The aim of the study was to evaluate the effectiveness and tolerability of topical sirolimus for facial angiofibromas in patients with tuberous sclerosis complex. METHODS: This was a prospective, single-blinded, cross-over study which involved twelve patients...
September 19, 2016: Indian Journal of Dermatology, Venereology and Leprology
Hui-Lei Wan, Hui-Zhi Chen, Xiu-Qin Shi
OBJECTIVE: To study the effects of Traditional Chinese Medicine Jianpi Chushi decoction and ointment on chronic eczema. METHODS: DNCB acetone solution was used to sensitize the skin of back and ears of 36 rats in order to establish chronic eczema model. A total of 36 rats were divided into four groups of 9 randomly including oral medicine group, external inunctum group, combination therapy group, and model control group respectively. Besides, the blank group of 4 healthy rats were set...
September 2016: Asian Pacific Journal of Tropical Medicine
Veronica Grassi, James William Butterworth, Layloma Latiffi
INTRODUCTION: Myiasis, parasitic infestation of the body by fly larvae, caused by the Cordylobia rodhaini is very rare with only fourteen cases published since 1970. We present a rare case of myiasis mimicking a breast abscess. PRESENTATION OF CASE: A 17-year-old female presented with a nodular ulcerative lesion in her left breast 14days following a trip to Ghana. She had been initially unsuccessfully treated with the antibiotic flucloxacillin following a misdiagnosis of a breast abscess...
2016: International Journal of Surgery Case Reports
Yutaka Tobo
Immersion freezing (ice nucleation by particles immersed in supercooled water) is a key process for forming ice in mixed-phase clouds. Immersion freezing experiments with particles in microliter-sized (millimeter-sized) water droplets are often applied to detecting very small numbers of ice nucleating particles (INPs). However, the application of such large droplets remains confined to the detection of INPs active at temperatures much higher than the homogeneous freezing limit, because of artifacts related to freezing of water droplets without added INPs at temperatures of -25 °C or higher on a supporting substrate...
2016: Scientific Reports
M Dolores Garrido, Macarena Egea, M Belén Linares, Beatriz Martínez, Ceferina Viera, Begoña Rubio, Francesc Borrisser-Pairó
This study represents a proposal for training sensory panels in androstenone (AND) perception in meat and meat products. The procedure consists of four main parts: (1) selection and training of a sensory panel (11 panelists) using standards with Vaseline oil media as carriers of AND and skatole (SKA); (2) developing a training method AND detection in meat; (3) dry cured meat product and (4) cooked meat product. All candidates were able to distinguish between AND, SKA and AND+SKA in Vaseline oil, order AND solutions with different concentrations and classify them in the three categories: low, medium and high...
December 2016: Meat Science
Kourosh Ghanbarzadeh, Omid Reza Tabatabaie, Ebrahim Salehifar, Massoud Amanlou, Ghasemali Khorasani
BACKGROUND: A suitable pharmacological substitute for the well-established surgical delay technique for random skin flaps to increase viability has been elusive. OBJECTIVE: To evaluate the effects of nitroglycerin and botulinum toxin type A on random flap survival in a rat model. METHODS: The present controlled experimental study was performed in the four groups of rats. One week after intervention in each group, the flap was raised and kept in situ, and flap necrosis was evaluated through follow-up...
2016: Plastic Surgery
Raman Malhotra, Kimia Ziahosseini, Cornelia Poitelea, Andre Litwin, Suresh Sagili
PURPOSE: To report outcomes of a randomized trial on the role of "active" Manuka honey on eyelid surgical wound healing. METHOD: Prospective, randomized, single-blinded study was performed for patients undergoing bilateral upper blepharoplasty. Vaseline was applied 4 times a day to both sides for 6 weeks and in addition, one eyelid was randomized to receive Manuka honey twice daily. Postoperative wounds were graded by a masked observer at 1 week, 1 month, and 4 months using Manchester scar scale and a modified eyelid scar grading scale...
July 13, 2016: Ophthalmic Plastic and Reconstructive Surgery
Noriyuki Nakashima
BACKGROUND: Dermal injury of the Eublepharis macularius (leopard gecko) often results in a loss of the spotted patterns. The scar is usually well recovered, but the spots and the tubercles may be lost depending on the size and part of the lesion. This report presents a surgical attempting, in which the pigments in the edge of the remaining skin flap are partially preserved to maximally restore the natural pigmentation patterns during the course of dermal regeneration. CASE PRESENTATION: A four-year-old female lizard E...
2016: BMC Veterinary Research
G Rea, F Perna, G Calabrese, A Molino, T Valente, A Vatrella
Lipoid pneumonia is an uncommon disorder characterized by accumulation of lipid components into the interstitial and alveolar compartment. The usual classification distinguishes endogenous and exogenous and acute or chronic forms, related to the type of fats, the amount of damage and the time of exposure. We describe a case of exogenous lipoid pneumonia by inhalation of vaseline used for cleaning of the tracheostoma in a 63-year-old female, presenting as cough, worsening dyspnea in few weeks. The diagnosis was finally established with a re-evaluation of BAL with specific staining for lipids, revealing the presence of foamy macrophages lipids rich, according to HRCT findings...
May 2016: Translational Medicine @ UniSa
Courtney Maierhofer, Cara E Rice, Shu-Hua Wang, Karen S Fields, Melissa Ervin, Abigail Norris Turner
BACKGROUND: Use of lubricants during anal intercourse is very common among men who have sex with men. However, few studies have evaluated associations between specific lubricants and rectal sexually transmitted infections (STIs). METHODS: Between July 2012 and October 2013, we conducted a cross-sectional study of men who have sex with men recruited from an urban, public sexual health clinic. In a self-administered survey, participants identified the lubricants used and frequency of lubricant use in the previous three months...
July 2016: Sexually Transmitted Diseases
Pedro Alves da Rocha-Filho, Mônica Maruno, Márcio Ferrari, José Fernando Topan
The Brazilian biodiversity offers a multiplicity of raw materials with great potential in cosmetics industry applications. Some vegetable oils and fatty esters increase skin hydration by occlusivity, keeping the skin hydrated and with a shiny appearance. Sunflower (Helianthus annus L.) oil is widely employed in cosmetic emulsions in the form of soaps, creams, moisturizers and skin cleansers due to the presence of polyphenols and its high vitamin E content. Liquid crystals are systems with many applications in both pharmaceutical and cosmetic formulations and are easily detected by microscopy under polarized light due to their birefringence properties...
2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Di-Qing Luo, Hui-Hui Wu, Yu-Kun Zhao, Juan-Hua Liu, Fang Wang
Imiquimod (IMQ)-induced mouse psoriatic model is one of the useful models displaying most of psoriatic features. To compare the modeling efficacy of different IMQ creams, we induced the psoriatic models by topically applying two different brands of IMQ 5% creams to the shaved Balb/c mice skin and assessed the results. Balb/c female mice (n = 24) 8-12 weeks of age were randomly divided into experimental groups A (Likejie), B (Aldara), and control group C (Vaseline); Likejie, Aldara, or Vaseline was topically applied to the back skin for mice in groups A, B, and C, respectively, for six consecutive days...
October 2016: Experimental Biology and Medicine
Daisuke Kimura, Shoji Uga
Parasitic specimens derived from protozoans and helminths have variable thickness. Therefore, microscopic observation of these specimens requires a preparation technique where the space between the coverslip and slide glass can be freely adjusted. However, standard suspension methods for parasites do not afford this flexibility due to the thickness of eggs and parasites. Mounting too large of a sample results in a floating coverslip, making observation difficult. In this article, we developed vaseline-paraffin solution (VPS) as a simple and effective mounting technique for observation of suspended parasite specimens...
May 13, 2016: Parasitology International
Vivian C Paulun, Karl R Gegenfurtner, Melvyn A Goodale, Roland W Fleming
Successfully picking up and handling objects requires taking into account their physical properties (e.g., material) and position relative to the body. Such features are often inferred by sight, but it remains unclear to what extent observers vary their actions depending on the perceived properties. To investigate this, we asked participants to grasp, lift and carry cylinders to a goal location with a precision grip. The cylinders were made of four different materials (Styrofoam, wood, brass and an additional brass cylinder covered with Vaseline) and were presented at six different orientations with respect to the participant (0°, 30°, 60°, 90°, 120°, 150°)...
August 2016: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
Mariana de Almeida Basílio, Filipe de Oliveira Abi-Rached, Luis Eduardo Butignon, João Neudenir Arioli Filho
PURPOSE: To evaluate the effectiveness of abutment screws coated with liquid Vaseline on the screw-joint stability of yttria-stabilized tetragonal zirconia (Y-TZP) abutment systems. MATERIALS AND METHODS: Forty Y-TZP prefabricated abutments, 20 Neodent and 20 Bionnovation, were tightened to 20 Ncm on their respective external hexagon implants, and divided into four groups (n = 10) according to the screws: coated with Vaseline or uncoated. The removal torque (RT) value of the abutment screw was measured before and after loading...
February 8, 2016: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
Nina I Niebuhr, Wibke Johnen, Timur Güldaglar, Armin Runz, Gernot Echner, Philipp Mann, Christian Möhler, Asja Pfaffenberger, Oliver Jäkel, Steffen Greilich
PURPOSE: Phantom surrogates were developed to allow multimodal [computed tomography (CT), magnetic resonance imaging (MRI), and teletherapy] and anthropomorphic tissue simulation as well as materials and methods to construct deformable organ shapes and anthropomorphic bone models. METHODS: Agarose gels of variable concentrations and loadings were investigated to simulate various soft tissue types. Oils, fats, and Vaseline were investigated as surrogates for adipose tissue and bone marrow...
February 2016: Medical Physics
Erika Jensen-Jarolim, Franziska Roth-Walter, Erich Leitner, Stefan Buchleitner, Harald Vogelsang, Tamar Kinaciyan
BACKGROUND: Cinnamon aldehyde (alias cinnamaldehyde) is widely used in food, textile or cosmetic industry. It is mostly associated with contact allergy, but immediate type allergies have been reported. The present study was triggered by a case of anaphylactic events to cinnamon in food and upon skin prick test. We investigated a possible correlation of exposure to a disco fog machine and/or shisha consumption with immediate type hypersensitivity to cinnamon aldehyde in the patient and healthy volunteers...
2016: World Allergy Organization Journal
Theresa Brückner, Martha Schamel, Alexander C Kübler, Jürgen Groll, Uwe Gbureck
UNLABELLED: Classic bone wax is associated with drawbacks such as the risk of infection, inflammation and hindered osteogenesis. Here, we developed a novel self-setting bone wax on the basis of hydrophilic poly(ethylene glycol) (PEG) and hydroxyapatite (HA) forming calcium phosphate cement (CPC), to overcome the problems that are linked to the use of conventional beeswax systems. Amounts of up to 10 wt.% of pregelatinized starch were additionally supplemented as hemostatic agent. After exposure to a humid environment, the PEG phase dissolved and was exchanged by penetrating water that interacted with the HA precursor (tetracalcium phosphate (TTCP)/monetite) to form highly porous, nanocrystalline HA via a dissolution/precipitation reaction...
March 2016: Acta Biomaterialia
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