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Late Menarche

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https://www.readbyqxmd.com/read/28182101/periductal-mastitis-an-inflammatory-disease-related-to-bacterial-infection-and-consequent-immune-responses
#1
Lu Liu, Fei Zhou, Pin Wang, Lixiang Yu, Zhongbing Ma, Yuyang Li, Dezong Gao, Qiang Zhang, Liang Li, Zhigang Yu
Periductal mastitis (PDM) is a prolonged inflammatory disease, but the cause of PDM is poorly understood. In the present case control study, 87 PDM and 87 healthy controls were enrolled and the results were evaluated to identify the significant risk factors for PDM. To investigate the roles of bacterial infection and critical cytokines expression, 16S rRNA gene sequencing and bacterial culturing were conducted. We also measured the levels of interferon-γ, interleukin-12A, and interleukin-17A by semiquantitative immunohistochemistry method...
2017: Mediators of Inflammation
https://www.readbyqxmd.com/read/28142040/bmi-reproductive-factors-and-breast-cancer-molecular-subtypes-a-case-control-study-and-meta-analysis
#2
Hui Li, Xuezheng Sun, Erline Miller, Qiong Wang, Ping Tao, Li Liu, Ying Zhao, Mengjie Wang, Yana Qi, Jiayuan Li
BACKGROUND: The effects of body mass index (BMI) and reproductive factors may vary among breast cancer molecular subtypes, evidence of which is lacking in East Asia. METHODS: From 2002 to 2010, 1256 breast cancer patients and 1416 healthy women were recruited. Anthropometric and reproductive factors were collected from medical charts. Breast cancer subtype was defined by ER, PR, and HER2 status. Polytomous logistic regression was used to evaluate associations between risk factors and breast cancer subtypes, with subgroup analysis by menopausal status...
December 9, 2016: Journal of Epidemiology
https://www.readbyqxmd.com/read/28118209/menstrual-and-reproductive-factors-in-the-risk-of-thyroid-cancer-in-japanese-women-the-japan-public-health-center-based-prospective-study
#3
Sangah Shin, Norie Sawada, Eiko Saito, Taiki Yamaji, Motoki Iwasaki, Taichi Shimazu, Shizuka Sasazuki, Manami Inoue, Shoichiro Tsugane
The aim of this study was to evaluate the associations between menstrual and reproductive factors and thyroid cancer risk among Japanese women. A total 54 776 women aged 40-69 years completed a self-administered questionnaire, which included menstrual and reproductive history. During 1990-2012, 187 newly diagnosed cases of thyroid cancer were identified. Hazard ratios (HRs) and 95% confidence intervals (CIs) for menstrual and reproductive factors and incidence of thyroid cancer were estimated using Cox proportional hazards regression...
January 21, 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28086982/reproductive-factors-and-the-risk-of-triple-negative-breast-cancer-in-white-women-and-african-american-women-a-pooled-analysis
#4
Huiyan Ma, Giske Ursin, Xinxin Xu, Eunjung Lee, Kayo Togawa, Lei Duan, Yani Lu, Kathleen E Malone, Polly A Marchbanks, Jill A McDonald, Michael S Simon, Suzanne G Folger, Jane Sullivan-Halley, Dennis M Deapen, Michael F Press, Leslie Bernstein
BACKGROUND: Early age at menarche, nulliparity, late age at first completed pregnancy, and never having breastfed, are established breast cancer risk factors. However, among breast cancer subtypes, it remains unclear whether all of these are risk factors for triple-negative breast cancer (TNBC). METHODS: We evaluated the associations of these reproductive factors with TNBC, in 2658 patients with breast cancer (including 554 with TNBC) and 2448 controls aged 20-64 years, who participated in one of the three population-based case-control studies: the Women's Contraceptive and Reproductive Experiences Study, the Women's Breast Carcinoma in situ Study, or the Women's Learning the Influence of Family and Environment Study...
January 13, 2017: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/27996108/effect-of-reproductive-history-and-exogenous-hormone-use-on-cognitive-function-in-mid-and-late-life
#5
Roksana Karim, Ha Dang, Victor W Henderson, Howard N Hodis, Jan St John, Roberta D Brinton, Wendy J Mack
OBJECTIVES: To investigate the association between reproductive history indicators of hormonal exposure, including reproductive period, pregnancy, and use of hormonal contraceptives, and mid- and late-life cognition in postmenopausal women. DESIGN: Analysis of baseline data from two randomized clinical trials: the Women's Isoflavone Soy Health and the Early vs Late Intervention Trial of Estradiol. SETTING: University academic research center...
December 2016: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27919437/fertile-lifespan-characteristics-and-all-cause-and-cause-specific-mortality-among-postmenopausal-women-the-rotterdam-study
#6
Loes Jaspers, Maryam Kavousi, Nicole S Erler, Albert Hofman, Joop S E Laven, Oscar H Franco
OBJECTIVE: To characterize the relation between established and previously unexplored characteristics of the fertile life with all-cause and cause-specific mortality. DESIGN: Prospective cohort study. SETTING: Not applicable. PATIENT(S): A total of 4,076 postmenopausal women. INTERVENTION(S): Women's fertile lifespan (age at menarche to menopause), number of children, maternal age at first and last child, maternal lifespan (interval between maternal age at first and last child), postmaternal fertile lifespan (interval between age at last child and menopause), lifetime cumulative number of menstrual cycles, and unopposed cumulative endogenous estrogen (E) exposure...
February 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/27880720/the-impact-of-reproductive-life-on-breast-cancer-risk-in-women-with-family-history-or-brca-mutation
#7
Angela Toss, Giovanni Grandi, Angelo Cagnacci, Luigi Marcheselli, Silvia Pavesi, Elisabetta De Matteis, Elisabetta Razzaboni, Chiara Tomasello, Stefano Cascinu, Laura Cortesi
Reproductive history and exogenous hormonal exposures are acknowledged risk factors for breast cancer in the general population. In women at increased breast cancer risk for genetic predisposition or positive family history, data regarding these risk factors are limited or conflicting, and recommendations for these categories are unclear. We evaluated the characteristics of reproductive life in 2522 women at increased genetic or familial breast cancer risk attending our Family Cancer Center. Breast cancers in BRCA mutation carriers were more likely to be hormone receptor negative, diagnosed at 35 years or before and multiple during the lifetime than tumors in women at increased familial risk, while the distribution of invasive cancers and HER2 positive tumors was similar in the different risk groups...
November 17, 2016: Oncotarget
https://www.readbyqxmd.com/read/27836305/age-at-menarche-and-risk-of-major-cardiovascular-diseases-evidence-of-birth-cohort-effects-from-a-prospective-study-of-300-000-chinese-women
#8
Ling Yang, Liming Li, Iona Y Millwood, Sanne A E Peters, Yiping Chen, Yu Guo, Zheng Bian, Xiaofang Chen, Lingli Chen, Shixian Feng, Silu Lv, Zhigang Pang, Mark Woodward, Zhengming Chen
BACKGROUND: Previous studies of mostly Western women have reported inconsistent findings on the association between age at menarche and risk of cardiovascular disease (CVD). Little is known about the association in China where there has been a large intergenerational decrease in women's mean age at menarche. METHODS: The China Kadoorie Biobank recruited 302,632 women aged 30-79 (mean 50.5)years in 2004-8 from 10 diverse regional sites across China. During 7years follow-up, 14,111 incident cases of stroke, 14,093 of coronary heart disease (CHD), and 3200 CVD deaths were reported among 281,491 women who had no prior history of CVD at baseline...
January 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/27780981/longitudinal-observation-of-serum-anti-m%C3%A3-llerian-hormone-in-three-girls-after-cancer-treatment
#9
Yoko Miyoshi, Kie Yasuda, Makiko Tachibana, Hisao Yoshida, Emiko Miyashita, Takako Miyamura, Yoshiko Hashii, Kae Hashimoto, Tadashi Kimura, Keiichi Ozono
Gonadal dysfunction and infertility are major endocrinological late effects among childhood cancer survivors. Chemotherapy and radiation have gonadotoxic effects and diminish the ovarian reserve. The serum concentration of anti-Müllerian hormone (AMH) is a useful marker of ovarian reserve in survivors. We conducted a longitudinal study to investigate the variations of AMH in evaluating the acute and chronic effects of cancer therapy on the ovary. Three young female patients with different hematological diseases were registered, and their medical records were reviewed...
October 2016: Clinical Pediatric Endocrinology: Case Reports and Clinical Investigations: Official Journal of the Japanese Society for Pediatric Endocrinology
https://www.readbyqxmd.com/read/27737576/changes-in-clavicle-length-and-maturation-in-americans-1840-1980
#10
Natalie R Langley, Sandra Cridlin
Secular changes refer to short-term biological changes ostensibly due to environmental factors. Two well-documented secular trends in many populations are earlier age of menarche and increasing stature. This study synthesizes data on maximum clavicle length and fusion of the medial epiphysis in 1840-1980 American birth cohorts to provide a comprehensive assessment of developmental and morphological change in the clavicle. Clavicles from the Hamann-Todd Human Osteological Collection (n = 354), McKern and Stewart Korean War males (n = 341), Forensic Anthropology Data Bank (n = 1,239), and the McCormick Clavicle Collection (n = 1,137) were used in the analysis...
January 2016: Human Biology
https://www.readbyqxmd.com/read/27699734/-overview-of-endometrial-cancer
#11
Chia-Chun Li, Tsui-Hsia Feng
Endometrial cancer is the most common gynecological cancer and the sixth most common cancer among women in Taiwan. Risk factors for endometrial cancer include obesity, long-term estrogen replacement therapy, diabetes mellitus, hypertension, nulliparty, early age at menarche, late age at menopause, and tamoxifen therapy. Most women with endometrial cancer exhibit abnormal uterine bleeding. Endometrial cancer is often diagnosed at stage I. Surgery alone is the primary treatment for stage I endometrial cancer...
October 2016: Hu Li za Zhi the Journal of Nursing
https://www.readbyqxmd.com/read/27696903/early-pubertal-timing-is-common-among-adolescent-girl-to-boy-sex-reassignment-applicants
#12
Maria Sumia, Nina Lindberg, Marja Työläjärvi, Riittakerttu Kaltiala-Heino
OBJECTIVES: The aim of our study was to explore whether gender dysphoria in adolescent girls is associated with early pubertal timing. METHODS: We compared menarcheal timing among 52 adolescent girl-to-boy sex reassignment (SR) applicants with that of 644 adolescent girls who participated in an adolescent population mental health survey. RESULTS: Of the population girls, 21% presented with early (≤11 years), 61% with normative (12-13 years) and 19% with late (≥14 years) menarcheal timing; among the SR applicants, 42% presented with early, 46% with normative and 12% with late menarcheal timing (p = 0...
December 2016: European Journal of Contraception & Reproductive Health Care
https://www.readbyqxmd.com/read/27692528/pediatric-idiopathic-intracranial-hypertension-age-gender-and-anthropometric-features-at-diagnosis-in-a-large-retrospective-multisite-cohort
#13
Claire A Sheldon, Grace L Paley, Rui Xiao, Anat Kesler, Ori Eyal, Melissa W Ko, Chantal J Boisvert, Robert A Avery, Vincenzo Salpietro, Paul H Phillips, Gena Heidary, Shana E McCormack, Grant T Liu
PURPOSE: To examine anthropometric and maturational characteristics at diagnosis in pediatric idiopathic intracranial hypertension (IIH). DESIGN: Retrospective, international, multisite study. PARTICIPANTS: Pediatric patients (2-18 years of age at diagnosis) with IIH. MAIN OUTCOME MEASURES: Body mass index (BMI), height, and weight Z-scores; sexual maturation. METHODS: Cases of IIH were identified retrospectively based on diagnostic code, pediatric neuro-ophthalmologist databases, or both and updated diagnostic criteria (2013) were applied to confirm definite IIH...
November 2016: Ophthalmology
https://www.readbyqxmd.com/read/27662834/age-at-menarche-in-korean-adolescents-trends-and-influencing-factors
#14
Mee-Hwa Lee, Shin Hye Kim, Minkyung Oh, Kuk-Wha Lee, Mi-Jung Park
BACKGROUND: An increased incidence of central precocious puberty has been recently reported in South Korea, which suggests an ongoing downward trend in pubertal development in the Korean population. We aimed to verify the trend in age at menarche in young Korean women during the last decade and associated factors. METHODS: We analyzed a population-based sample of 3409 Korean girls, aged 10-18 years, using data from the Korean National Health and Nutrition Examination Surveys (KNHANES) II (2001), III (2005), IV (2007-2009), and V (2010 and 2011)...
2016: Reproductive Health
https://www.readbyqxmd.com/read/27660104/impact-of-the-age-at-menarche-on-body-composition-in-adulthood-results-from-two-birth-cohort-studies
#15
Susana Bubach, Ana Maria Baptista Menezes, Fernando Celso Barros, Fernando César Wehrmeister, Helen Gonçalves, Maria Cecília Formoso Assunção, Bernardo Lessa Horta
BACKGROUND: Evidence suggests that early menarche is positively associated with adiposity in adulthood. However, it is important to assess whether this association is due to early menarche or to the association of adiposity in late childhood with age at menarche. We evaluated the association between age at menarche and body composition in adolescence and adulthood, among subjects who have been prospectively followed in two Brazilian birth cohort studies. METHODS: In 1982 and 1993, the hospitals births in Pelotas were identified, and these subjects have been followed for several times...
2016: BMC Public Health
https://www.readbyqxmd.com/read/27635377/timing-of-spermarche-and-menarche-are-associated-with-physical-activity-and-sedentary-behavior-among-korean-adolescents
#16
Eun-Young Lee, Roman Pabayo, Ichiro Kawachi
OBJECTIVES: This study examined the timing of menarche and spermarche and their associations with physical activity (PA) and sedentary behavior (SB) after controlling for body mass index (BMI). METHODS: Multiple logistic regression analyses were conducted to determine whether the timing of menarche in girls and spermarche in boys is associated with PA and SB independent of BMI in a nationally representative sample of Korean adolescents (13-18 years; N = 74,186)...
August 2016: Osong Public Health and Research Perspectives
https://www.readbyqxmd.com/read/27632570/reproductive-and-lifestyle-factors-associated-with-endometriosis-in-a-large-cross-sectional-population-sample
#17
Rama Saha, Ralf Kuja-Halkola, Per Tornvall, Lena Marions
OBJECTIVES: Despite the high prevalence of endometriosis among women of reproductive age, risk factors or markers for developing the condition remain largely unknown. Many of the published studies are based on small selected samples. We therefore investigated the relationships of reproductive and lifestyle factors with endometriosis in a large sample of Swedish female twins. MATERIAL AND METHODS: This cross-sectional study included 28,822 women. Among these, endometriosis was reported by 1,228 women and the self-reported diagnosis was confirmed by medical records...
February 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/27600751/longitudinal-effects-of-self-report-pubertal-timing-and-menarcheal-age-on-adolescent-psychological-and-behavioral-outcomes-in-female-youths-from-northern-taiwan
#18
Chih-Ting Lee, Meng-Che Tsai, Chung-Ying Lin, Carol Strong
BACKGROUND: Early puberty is linked to adverse developmental outcomes in adolescents in Western societies. However, little is known about this relationship in an East Asian context. In addition, whether the impact of subjective pubertal timing (PT) and menarcheal age (MA) on adolescent psychosocial development persists into early adulthood remains unclear and is worthy of investigation. METHODS: A subset of data was retrieved from the Taiwan Youth Project, which recruited and followed a longitudinal cohort of 7(th)- and 9(th)-grade female Taiwanese students from 2000 to 2007...
July 26, 2016: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/27564696/pattern-of-menarche-age-normal-early-and-late-and-its-relationship-with-some-demographic-characteristics-in-girls-and-their-parents
#19
Naeimeh Tayebi, Zahra Yazdznpanahi, Shahrzad Yektatalab, Marzieh Akbarzadeh, Najaf Zare
BACKGROUND: Menarche age is an indicator of a girl's puberty besides the clinical assessment of detecting deviations. This study aimed to search the pattern of menarche age (normal, early and late) and its relationship with some demographic characteristics in girls and their parents. METHODS: This cross-sectional study was done on girls aged between 9 and 18 years old in Shiraz city. About 2000 students were selected through cluster sampling. Data collection was done by applying a demographic information form...
August 26, 2016: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/27524817/adiposity-in-relation-to-age-at-menarche-and-other-reproductive-factors-among-300%C3%A2-000-chinese-women-findings-from-china-kadoorie-biobank-study
#20
Ling Yang, Liming Li, Iona Y Millwood, Sarah Lewington, Yu Guo, Paul Sherliker, Sanne Ae Peters, Zheng Bian, Xianping Wu, Min Yu, Huilin Liu, Hongmei Wang, Enke Mao, Junshi Chen, Mark Woodward, Richard Peto, Zhengming Chen
BACKGROUND: Adiposity is increasing rapidly in China but little is known about the relevance to it of women's reproductive factors, which differ inter-generationally and from that in the West. We assess associations of adiposity with life-course reproductive factors in Chinese women. METHODS: In 2004-08, the nationwide China Kadoorie Biobank recruited 303 000 women aged 30-79 (mean 50) years from 10 diverse regions. Multivariable linear regression was used to examine associations of reproductive factors (e...
August 14, 2016: International Journal of Epidemiology
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