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Late Menarche

Natalie R Langley, Sandra Cridlin
Secular changes refer to short-term biological changes ostensibly due to environmental factors. Two well-documented secular trends in many populations are earlier age of menarche and increasing stature. This study synthesizes data on maximum clavicle length and fusion of the medial epiphysis in 1840-1980 American birth cohorts to provide a comprehensive assessment of developmental and morphological change in the clavicle. Clavicles from the Hamann-Todd Human Osteological Collection (n = 354), McKern and Stewart Korean War males (n = 341), Forensic Anthropology Data Bank (n = 1,239), and the McCormick Clavicle Collection (n = 1,137) were used in the analysis...
January 2016: Human Biology
Chia-Chun Li, Tsui-Hsia Feng
Endometrial cancer is the most common gynecological cancer and the sixth most common cancer among women in Taiwan. Risk factors for endometrial cancer include obesity, long-term estrogen replacement therapy, diabetes mellitus, hypertension, nulliparty, early age at menarche, late age at menopause, and tamoxifen therapy. Most women with endometrial cancer exhibit abnormal uterine bleeding. Endometrial cancer is often diagnosed at stage I. Surgery alone is the primary treatment for stage I endometrial cancer...
October 2016: Hu Li za Zhi the Journal of Nursing
Maria Sumia, Nina Lindberg, Marja Työläjärvi, Riittakerttu Kaltiala-Heino
OBJECTIVES: The aim of our study was to explore whether gender dysphoria in adolescent girls is associated with early pubertal timing. METHODS: We compared menarcheal timing among 52 adolescent girl-to-boy sex reassignment (SR) applicants with that of 644 adolescent girls who participated in an adolescent population mental health survey. RESULTS: Of the population girls, 21% presented with early (≤11 years), 61% with normative (12-13 years) and 19% with late (≥14 years) menarcheal timing; among the SR applicants, 42% presented with early, 46% with normative and 12% with late menarcheal timing (p = 0...
October 3, 2016: European Journal of Contraception & Reproductive Health Care
Claire A Sheldon, Grace L Paley, Rui Xiao, Anat Kesler, Ori Eyal, Melissa W Ko, Chantal J Boisvert, Robert A Avery, Vincenzo Salpietro, Paul H Phillips, Gena Heidary, Shana E McCormack, Grant T Liu
PURPOSE: To examine anthropometric and maturational characteristics at diagnosis in pediatric idiopathic intracranial hypertension (IIH). DESIGN: Retrospective, international, multisite study. PARTICIPANTS: Pediatric patients (2-18 years of age at diagnosis) with IIH. MAIN OUTCOME MEASURES: Body mass index (BMI), height, and weight Z-scores; sexual maturation. METHODS: Cases of IIH were identified retrospectively based on diagnostic code, pediatric neuro-ophthalmologist databases, or both and updated diagnostic criteria (2013) were applied to confirm definite IIH...
September 27, 2016: Ophthalmology
Mee-Hwa Lee, Shin Hye Kim, Minkyung Oh, Kuk-Wha Lee, Mi-Jung Park
BACKGROUND: An increased incidence of central precocious puberty has been recently reported in South Korea, which suggests an ongoing downward trend in pubertal development in the Korean population. We aimed to verify the trend in age at menarche in young Korean women during the last decade and associated factors. METHODS: We analyzed a population-based sample of 3409 Korean girls, aged 10-18 years, using data from the Korean National Health and Nutrition Examination Surveys (KNHANES) II (2001), III (2005), IV (2007-2009), and V (2010 and 2011)...
2016: Reproductive Health
Susana Bubach, Ana Maria Baptista Menezes, Fernando Celso Barros, Fernando César Wehrmeister, Helen Gonçalves, Maria Cecília Formoso Assunção, Bernardo Lessa Horta
BACKGROUND: Evidence suggests that early menarche is positively associated with adiposity in adulthood. However, it is important to assess whether this association is due to early menarche or to the association of adiposity in late childhood with age at menarche. We evaluated the association between age at menarche and body composition in adolescence and adulthood, among subjects who have been prospectively followed in two Brazilian birth cohort studies. METHODS: In 1982 and 1993, the hospitals births in Pelotas were identified, and these subjects have been followed for several times...
2016: BMC Public Health
Eun-Young Lee, Roman Pabayo, Ichiro Kawachi
OBJECTIVES: This study examined the timing of menarche and spermarche and their associations with physical activity (PA) and sedentary behavior (SB) after controlling for body mass index (BMI). METHODS: Multiple logistic regression analyses were conducted to determine whether the timing of menarche in girls and spermarche in boys is associated with PA and SB independent of BMI in a nationally representative sample of Korean adolescents (13-18 years; N = 74,186)...
August 2016: Osong Public Health and Research Perspectives
Rama Saha, Ralf Kuja-Halkola, Per Tornvall, Lena Marions
OBJECTIVES: Despite the high prevalence of endometriosis among women of reproductive age, risk factors or markers for developing the condition remain largely unknown. Many of the published studies are based on small selected samples. We therefore investigated the relationships of reproductive and lifestyle factors with endometriosis in a large sample of Swedish female twins. MATERIAL AND METHODS: This cross-sectional study included 28,822 women. Among these, endometriosis was reported by 1,228 women and the self-reported diagnosis was confirmed by medical records...
September 15, 2016: Journal of Women's Health
Chih-Ting Lee, Meng-Che Tsai, Chung-Ying Lin, Carol Strong
BACKGROUND: Early puberty is linked to adverse developmental outcomes in adolescents in Western societies. However, little is known about this relationship in an East Asian context. In addition, whether the impact of subjective pubertal timing (PT) and menarcheal age (MA) on adolescent psychosocial development persists into early adulthood remains unclear and is worthy of investigation. METHODS: A subset of data was retrieved from the Taiwan Youth Project, which recruited and followed a longitudinal cohort of 7(th)- and 9(th)-grade female Taiwanese students from 2000 to 2007...
July 26, 2016: Pediatrics and Neonatology
Naeimeh Tayebi, Zahra Yazdznpanahi, Shahrzad Yektatalab, Marzieh Akbarzadeh, Najaf Zare
BACKGROUND: Menarche age is an indicator of a girl's puberty besides the clinical assessment of detecting deviations. This study aimed to search the pattern of menarche age (normal, early and late) and its relationship with some demographic characteristics in girls and their parents. METHODS: This cross-sectional study was done on girls aged between 9 and 18 years old in Shiraz city. About 2000 students were selected through cluster sampling. Data collection was done by applying a demographic information form...
August 26, 2016: International Journal of Adolescent Medicine and Health
Ling Yang, Liming Li, Iona Y Millwood, Sarah Lewington, Yu Guo, Paul Sherliker, Sanne Ae Peters, Zheng Bian, Xianping Wu, Min Yu, Huilin Liu, Hongmei Wang, Enke Mao, Junshi Chen, Mark Woodward, Richard Peto, Zhengming Chen
BACKGROUND: Adiposity is increasing rapidly in China but little is known about the relevance to it of women's reproductive factors, which differ inter-generationally and from that in the West. We assess associations of adiposity with life-course reproductive factors in Chinese women. METHODS: In 2004-08, the nationwide China Kadoorie Biobank recruited 303 000 women aged 30-79 (mean 50) years from 10 diverse regions. Multivariable linear regression was used to examine associations of reproductive factors (e...
August 14, 2016: International Journal of Epidemiology
Aladdin H Shadyab, Caroline A Macera, Richard A Shaffer, Sonia Jain, Linda C Gallo, Margery L S Gass, Molly E Waring, Marcia L Stefanick, Andrea Z LaCroix
OBJECTIVE: The aim of the present study was to investigate associations between reproductive factors and survival to age 90 years. METHODS: This was a prospective study of postmenopausal women from the Women's Health Initiative recruited from 1993 to 1998 and followed until the last outcomes evaluation on August 29, 2014. Participants included 16,251 women born on or before August 29, 1924 for whom survival to age 90 during follow-up was ascertained. Women were classified as having survived to age 90 (exceptional longevity) or died before age 90...
July 25, 2016: Menopause: the Journal of the North American Menopause Society
Yun Shen, Hui Hu, Brandie D Taylor, Haidong Kan, Xiaohui Xu
OBJECTIVES: To examine the association between early menarche and gestational diabetes mellitus (GDM). METHODS: Data from the National Health and Nutrition Examination Survey 2007-2012 were used to investigate the association between age at menarche and the risk of GDM at first birth among 5914 women. A growth mixture model was used to detect distinctive menarche onset patterns based on self-reported age at menarche. Logistic regression models were then used to examine the associations between menarche initiation patterns and GDM after adjusting for sociodemographic factors, family history of diabetes mellitus, lifetime greatest Body Mass Index, smoking status, and physical activity level...
July 25, 2016: Maternal and Child Health Journal
Patrick Puttemans, Giuseppe Benagiano, Caroline Gargett, Roberto Romero, Sun-Wei Guo, Ivo Brosens
Neonatal uterine bleeding (NUB) occurs in approximately 5% of newborns and is generally considered to be of little clinical significance. However, the real clinical importance of this condition and its long-term implications remain to be determined. The reason why NUB is rare despite high circulating levels of progesterone can be attributed to a progesterone resistance present in a majority of neonates. Recent work indicates that NUB represents a significant biomarker for events that can occur later-on during adolescence...
August 18, 2016: Journal of Maternal-fetal & Neonatal Medicine
Tsz Chun Lai, Gabriel Matthew Leung, C Mary Schooling
BACKGROUND: Age of puberty has declined substantially in developed settings and is now declining in the rest of the world with economic development. Early age of puberty is associated with non-communicable diseases in adulthood, and may be a long-term driver of population health with effects over generations. In a non-Western setting, we examined the association of maternal age of menarche with blood pressure in late childhood/adolescence. METHODS: We used generalised estimating equations to estimate the adjusted association of maternal age of menarche with age-, sex- and height-adjusted blood pressure z-score from 10 to 16 years in Hong Kong's population-representative birth cohort, "Children of 1997" (n = 8327)...
2016: PloS One
Olga Golubnitschaja, Manuel Debald, Kristina Yeghiazaryan, Walther Kuhn, Martin Pešta, Vincenzo Costigliola, Godfrey Grech
Rapidly increasing incidence of breast cancer is a new social challenge resulting from a spectrum of internal and external risk factors which appear to be well accepted as an attribute of the early twenty-first century, being, however, new for female sub-populations compared to the past. These include altered socio-economical conditions such as occupational exposure, rotating shift work, specific environmental factors (increased pollution and environmental toxicity, altered dietary habits, quality and composition of meal) as well as consequently shifted and/or adapted physiologic factors such as lower age at menarche, late age of first full-term pregnancy, if any, shorter periods of breastfeeding and later menopause...
July 22, 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
Jason Y Y Wong, Po-Yin Chang, Ellen B Gold, Wesley O Johnson, Jennifer S Lee
OBJECTIVE: To assess the longitudinal relationship of environmental tobacco smoke (ETS) exposure during midlife, and its interaction with active smoking, with the risk of late-diagnosis incident uterine fibroids during the menopausal transition. DESIGN: Thirteen-year prospective cohort study. SETTING: Not applicable. PATIENT(S): Community-based, multiracial/ethnic cohort of 2,575 women aged 42 to 52 years at baseline, undergoing the menopausal transition...
October 2016: Fertility and Sterility
Amos R Mwakigonja, Happiness Rabiel, Naboth A Mbembati, Leonard E K Lema
BACKGROUND: Breast cancer is the commonest female malignancy globally and the second (after uterine cervix) in sub-Saharan Africa including Tanzania. Prognostic indicators reportedly influence post-mastectomy adjuvant therapy by predicting risks on survival and recurrence although in Tanzania this data is lacking. Here, we evaluate the pattern of prognostic and risk indicators among women with breast cancer undergoing modified-radical-mastectomy (MRM) at Muhimbili National Hospital (MNH) and Tumaini Hospital (TH), Dar es Salaam, Tanzania...
2016: Infectious Agents and Cancer
Antonio Sifuentes-Álvarez, Lucy Yolanda Castañeda-Martínez, Mario Lugo-Nevares, Miguel Arturo Reyes-Romero
BACKGROUND: Breast cancer is a public health problem worldwide and is a priority for developing countries like ours, to establish preventive and early detection measures. In Mexico since 2006 breast cancer than cervical cancer as a cause of death in women aged 30-54 years and threatens all socioeconomic groups. The known risk factors for the occurrence of this neoplasm are early menarche, nulliparity, late age parity and late menopause and family history of breast cancer. OBJECTIVE: To determine the risk factors associated with breast cancer in women in the State of Durango...
November 2015: Ginecología y Obstetricia de México
Yasminur G Turdybekova, Raushan S Dosmagambetova, Symbat U Zhanabayeva, Gena V Bublik, Alik B Kubayev, Zhanbolat G Ibraibekov, Irina L Kopobayeva, Berikbay Zh Kultanov
In order to assess women's reproductive health in the Kyzylorda region (the Aral Sea) of Kazakhstan, 1406 women were involved in an integrated clinical-functional and laboratory examination, given regional and environmental ecological factors. The high level of endocrine gynecological pathology is indicated in the examined women. In both examined zones, there is a late menarche over 16 years old, which is 39%. It is indicated a trend towards younger age of menopause onset. Inflammatory diseases of the female genital organs affect a third of the examined women...
September 15, 2015: Open Access Macedonian Journal of Medical Sciences
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