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Late Menarche

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https://www.readbyqxmd.com/read/29112888/age-of-pubertal-onset-and-2nd-to-4th-digit-ratios-preliminary-findings
#1
Diane C Gooding, Blake H Chambers
BACKGROUND: The second to fourth digit ratio (2D:4D) is used as a marker of prenatal sex hormone exposure. The aim of this study was to evaluate the possible relation between digit ratio and age of pubertal onset. METHODS: Participants were 321 men and 202 women aged between 18 and 28 at the time of assessment who self-reported their onset of puberty (i.e., age at first conscious ejaculation or menarche). Participants' right and left digit lengths were measured from hand scans...
November 4, 2017: Early Human Development
https://www.readbyqxmd.com/read/29112597/association-of-age-at-menarche-with-obesity-and-hypertension-among-southwestern-chinese-women-a-new-finding
#2
Gang Liu, Yuan Yang, Wei Huang, Nan Zhang, Fan Zhang, Ge Li, Han Lei
OBJECTIVES: The purpose of this study was to assess the association of the age at menarche with obesity and hypertension among southwestern Chinese women. METHODS: Participants in a cross-sectional study were required to recall and complete a standard self-reporting questionnaire, including age at menarche and lifestyle habits. Cardiovascular risk factors were obtained from the questionnaire or a physical examination. The main outcomes were obesity and hypertension...
November 6, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28970852/clinicopathologic-characteristics-of-pregnancy-associated-breast-cancer-results-of-analysis-of-a-nationwide-breast-cancer-registry-database
#3
Yun Gyoung Kim, Ye Won Jeon, Byung Kyun Ko, Guiyun Sohn, Eun-Kyu Kim, Byung-In Moon, Hyun Jo Youn, Hyun-Ah Kim
PURPOSE: This study aimed to evaluate the clinicopathological characteristics of pregnancy-associated breast cancer (PABC) in comparison with non-pregnancy associated breast cancer (non-PABC). METHODS: A total of 344 eligible patients with PABC were identified in the Korean Breast Cancer Society Registry database. PABC was defined as ductal carcinoma in situ, invasive ductal carcinoma, or invasive lobular carcinoma diagnosed during pregnancy or within 1 year after the birth of a child...
September 2017: Journal of Breast Cancer
https://www.readbyqxmd.com/read/28951134/implications-of-pubertal-timing-for-romantic-relationship-quality-among-heterosexual-and-sexual-minority-young-adults
#4
Bianka M Reese, Sarah L Trinh, Carolyn T Halpern
PURPOSE: Relative to on-time or late-maturing peers, girls who begin puberty early typically begin romantic and sexual experiences earlier; however, advanced pubertal status does not necessarily coincide with commensurate interpersonal skills necessary for healthy romantic relationships. Research is limited on the long-term implications of early puberty for relationship quality, and virtually nothing is known about the social implications of early timing for sexual minority females. METHODS: Using linear regression, we examine longitudinal associations between two measures of girls' pubertal timing (self-perceived timing and menarcheal age) and romantic relationship quality in young adulthood, stratified by sexual orientation, among 5,568 females in waves I and IV of the National Longitudinal Study of Adolescent to Adult Health...
September 23, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28927079/new-use-of-microsatellite-instability-analysis-in-endometrial-cancer
#5
Haruko Kunitomi, Kouji Banno, Megumi Yanokura, Takashi Takeda, Moito Iijima, Kanako Nakamura, Miho Iida, Masataka Adachi, Keiko Watanabe, Yusuke Matoba, Yusuke Kobayashi, Eiichiro Tominaga, Daisuke Aoki
The increasing incidence of obesity and diabetes due to changes in diet, earlier menarche, delayed menopause, late marriage, and declining birth rate have resulted in an increase in the number of endometrial cancer cases over the last few decades. Although surgical therapy is sufficient for early endometrial cancer, there is no effective therapy for patients with advanced and recurrent endometrial cancer. The oncogenic mechanism of endometrial cancer involves microsatellite instability (MSI) caused by dysfunction of DNA mismatch repair genes in 30% of patients...
September 2017: Oncology Letters
https://www.readbyqxmd.com/read/28923182/association-between-age-at-menarche-and-cardiovascular-disease-a-systematic-review-on-risk-and-potential-mechanisms
#6
REVIEW
Janneke Luijken, Yvonne T van der Schouw, Daniëlle Mensink, N Charlotte Onland-Moret
Age at menarche (AAM) has been reported to be associated with the risk of cardiovascular disease (CVD), but the shape of and the mechanisms behind this association remain unclear. We reviewed the data on the association between AAM and different subtypes of CVD, and used shared genetic loci to identify possible mechanisms underlying this association using shared genetic association. We searched the databases of PubMed, Web of Science and Embase through to April 2017. We included articles with any clinically manifest CVD endpoint and for any ethnicity...
October 2017: Maturitas
https://www.readbyqxmd.com/read/28892211/early-menarche-is-associated-with-non-alcoholic-fatty-liver-disease-in-adulthood
#7
Kyung Hee Yi, Jin Soon Hwang, Se Won Lim, Jun Ah Lee, Dong Ho Kim, Jung Sub Lim
BACKGROUND: The aim of this study was to examine the association between early menarche (<12 years) and non-alcoholic fatty liver disease (NAFLD) in premenopausal women and to explore whether it is mediated by adult obesity and insulin resistance. METHODS: We analyzed data of premenopausal women, aged 15 or older, from the Korea National Health and Nutrition Examination Survey (2007-2009). We divided the women into 3 groups: early menarche, reference (12.00-15...
September 11, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28833893/nomenclature-of-primary-amenorrhea-a-proposal-document-of-the-japan-society-of-obstetrics-and-gynecology-committee-for-the-redefinition-of-primary-amenorrhea
#8
Makio Shozu, Hiroshi Ishikawa, Reiko Horikawa, Hideya Sakakibara, Shun-Ichiro Izumi, Takashi Ohba, Yasushi Hirota, Tsutomu Ogata, Yutaka Osuga, Koji Kugu
AIM: The aim of this study was to provide medical terms to describe the condition of a girl who should be evaluated for primary amenorrhea in order to facilitate intervention at an appropriate time. METHODS: We performed a literature and clinical guidelines search for recent practices with regard to menarche and discussed relevant cases that had been experienced by committee members. Additionally, we theoretically reviewed medical terms defined in the Glossary Book of Obstetrics and Gynecology in Japan (Japan Society of Obstetrics and Gynecology, 3rd edition)...
August 17, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28831686/food-versus-pharmacy-assessment-of-nutritional-and-pharmacological-strategies-to-improve-bone-health-in-energy-deficient-exercising-women
#9
REVIEW
Emily A Southmayd, Adelaide C Hellmers, Mary Jane De Souza
PURPOSE OF REVIEW: The review aims to summarize our current knowledge surrounding treatment strategies aimed at recovery of bone mass in energy-deficient women suffering from the Female Athlete Triad. RECENT FINDINGS: The independent and interactive contributions of energy status versus estrogen status on bone density, geometry, and strength have recently been reported, highlighting the importance of addressing both energy and estrogen in treatment strategies for bone health...
October 2017: Current Osteoporosis Reports
https://www.readbyqxmd.com/read/28828095/the-physique-of-elite-female-artistic-gymnasts-a-systematic-review
#10
Sarita Bacciotti, Adam Baxter-Jones, Adroaldo Gaya, José Maia
It has been suggested that successful young gymnasts are a highly select group in terms of the physique. This review summarizes the available literature on elite female gymnasts' anthropometric characteristics, somatotype, body composition and biological maturation. The main aims were to identify: (i) a common physique and (ii) the differences, if any, among competitive/performance levels. A systematic search was conducted online using five different databases. Of 407 putative papers, 17 fulfilled all criteria and were included in the review...
September 2017: Journal of Human Kinetics
https://www.readbyqxmd.com/read/28757148/transdiagnostic-psychiatric-disorder-risk-associated-with-early-age-of-menarche-a-latent-modeling-approach
#11
Jonathan M Platt, Natalie L Colich, Katie A McLaughlin, Dahsan Gary, Katherine M Keyes
BACKGROUND: Earlier age of pubertal maturation in females is associated with increased risk for mental health problems in adolescence, compared with on-time or later maturation. However, most investigations of pubertal timing and mental health consider risk for individual disorders and fail to account for comorbidity. A latent-modeling approach using a large, nationally representative sample could better explain the transdiagnostic nature of the consequences of early-onset puberty. METHODS: Data on age of menarche and mental disorders were drawn from a population-representative sample of adolescents (n=4925), ages 13-17...
November 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28750633/urinary-bisphenol-a-and-pubertal-development-in-chinese-school-aged-girls-a-cross-sectional-study
#12
Maohua Miao, Ziliang Wang, Xiaoqin Liu, Hong Liang, Zhijun Zhou, Hui Tan, Wei Yuan, De-Kun Li
BACKGROUND: Animal studies suggest that bisphenol A (BPA) may perturb pubertal development in females. However, evidence from human studies is limited. METHODS: This was a cross-sectional study to investigate the association between BPA exposure and pubertal development in school-aged girls. A total of 655 girls aged 9-18 years were selected from three schools in Shanghai, from May to June 2011. We collected one single spot urine sample from each girl. Urine BPA concentrations were measured by modified high-performance liquid chromatography and categorized according to LOD and the median of those above LOD...
July 27, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/28738458/-associations-between-season-of-birth-and-age-both-at-menarche-and-at-menopause
#13
J H Si, R R Meng, J Lyu, Y Guo, Z Bian, C Q Yu, L Yang, Y L Tan, P Pei, J S Chen, Z M Chen, L M Li
Objective: To examine the associations between season of birth and factors as age at menarche, age at menopause and reproductive span. Methods: A total of 285 186 female from the China Kadoorie Biobank, with complete data on critical variables and had menarche at 9-18 years old, were included. A total of 132 373 female with natural menopause were included for the analysis on age at menopause and reproductive span. Multiple linear regression models were used to assess the associations of birth season and the age at menarche, menopause, and reproductive span...
July 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28710506/obese-versus-normal-weight-late-adolescent-females-have-inferior-trabecular-bone-microarchitecture-a-pilot-case-control-study
#14
Joseph M Kindler, Norman K Pollock, Hannah L Ross, Christopher M Modlesky, Harshvardhan Singh, Emma M Laing, Richard D Lewis
Though still a topic of debate, the position that skeletal health is compromised with obesity has received support in the pediatric and adult literature. The limited data relating specifically to trabecular bone microarchitecture, however, have been relatively inconsistent. The aim of this pilot cross-sectional case-control study was to compare trabecular bone microarchitecture between obese (OB) and normal-weight (NW) late-adolescent females. A secondary aim was to compare diaphyseal cortical bone outcomes between these two groups...
July 14, 2017: Calcified Tissue International
https://www.readbyqxmd.com/read/28698185/age-at-menarche-and-late-adolescent-adiposity-associated-with-mammographic-density-on-processed-digital-mammograms-in-24-840-women
#15
Stacey E Alexeeff, Nnaemeka U Odo, Jafi A Lipson, Ninah Achacoso, Joseph H Rothstein, Martin J Yaffe, Rhea Y Liang, Luana Acton, Valerie McGuire, Alice S Whittemore, Daniel L Rubin, Weiva Sieh, Laurel A Habel
Background: High mammographic density is strongly associated with increased breast cancer risk. Some, but not all, risk factors for breast cancer are also associated with higher mammographic density.Methods: The study cohort (N = 24,840) was drawn from the Research Program in Genes, Environment and Health of Kaiser Permanente Northern California and included non-Hispanic white females ages 40 to 74 years with a full-field digital mammogram (FFDM). Percent density (PD) and dense area (DA) were measured by a radiological technologist using Cumulus...
September 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28610407/lack-of-hpv-in-benign-and-malignant-epithelial-ovarian-tumors-in-iran
#16
Farah Farzaneh, Seyed Alireza Nadji, Donya Khosravi, Maryam Sadat Hosseini, Mohammad Hashemi Bahremani, Mohammad Chehrazi, Ghazal Bagheri, Afsaneh Sigaroodi, Zahra Haghighatian
Background: Ovarian epithelial tumors one of the most common gynecological neoplasms; we here evaluated the presence of HPV in benign and malignant examples. Methods: In this cross-sectional study the records of 105 patients with epithelial ovarian tumors (benign and malignant) referred to Imam Hossein University Hospital from 2012 to 2015 were evaluated along with assessment of the presence of the HPV infection using PCR. Results: Among 105 patients, comprising 26 (24.8%) with malignant and 79 (75.2%) with benign lesions, the factors found to impact on malignancy were age at diagnosis, age at first pregnancy, number of pregnancies and hormonal status...
May 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28603694/estrogen-effects-on-the-mammary-gland-in-early-and-late-life-and-breast-cancer-risk
#17
REVIEW
Genevieve Victoria Dall, Kara Louise Britt
A woman has an increased risk of breast cancer if her lifelong estrogen exposure is increased due to an early menarche, a late menopause, and/or an absence of childbearing. For decades, it was presumed that the number of years of exposure drove the increased risk, however, recent epidemiological data have shown that early life exposure (young menarche) has a more significant effect on cancer risk than late menopause. Thus, rather than the overall exposure it seems that the timing of hormone exposure plays a major role in defining breast cancer risk...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28581683/the-effect-of-early-pregnancy-on-the-formation-of-obstetric-fistula
#18
Andrew Browning, Frederick Mbise, Phil Foden
OBJECTIVE: To assess the effect of early pregnancy on obstetric fistula. METHODS: A prospective observational study was conducted among patients with obstetric fistula caused by a long obstructed labor who presented at Selian Lutheran Hospital, Tanzania, or Kitovu Hospital, Uganda, between January 1, 2015, and January 31, 2016. Demographic and clinical variables were evaluated. RESULTS: Among 270 patients, 162 (60.0%) experienced their first pregnancy up to 2 years after menarche (early group) and 108 (40...
June 5, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28520646/relationship-between-pubertal-timing-and-chronic-nonspecific-pain-in-adolescent-girls-the-young-hunt3-study-2006-2008
#19
Barbro Kløven, Gry B Hoftun, Pål R Romundstad, Marite Rygg
The aim of this study was to examine a possible relationship between early puberty and chronic nonspecific pain in 13- to 18-year-old girls. All adolescents in Nord-Trøndelag County, Norway, were invited to participate in the Young-HUNT3 study (2006-2008). Of the invited girls, 81% answered the questionnaire and of these 3982 were 13 to 18 years of age. Menarche and perceived physical maturation were used as exposure measures. Early menarche was defined as <12 years, normal menarche as ≥12 and <14 years, and late menarche as ≥14 years...
May 16, 2017: Pain
https://www.readbyqxmd.com/read/28495176/pubertal-timing-and-cardiometabolic-markers-at-age-16-years
#20
Nina E Berentzen, Alet H Wijga, Lenie van Rossem, Dirkje S Postma, Ulrike Gehring, Henriëtte A Smit
OBJECTIVE: To examine the association between pubertal timing and cardiometabolic markers among adolescents. STUDY DESIGN: We used data from Dutch adolescents participating in a birth cohort study. The study population for the current study consisted of 799 adolescents of whom data were available for at least 1 of the exposure variables (pubertal timing and/or age at menarche) and any of the cardiometabolic markers (waist circumference, cholesterol, blood pressure [BP], glycated hemoglobin) measured at age 16 years...
August 2017: Journal of Pediatrics
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