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Late Menarche

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https://www.readbyqxmd.com/read/28395581/a-case-control-study-of-rheumatoid-arthritis-revealed-abdominal-obesity-and-environmental-risk-factor-interactions-in-northern-china
#1
Lingyu Fu, Jianming Zhang, Lei Jin, Yao Zhang, Saisai Cui, Meng Chen
BACKGROUND: The aim of this study was to evaluate new and previously hypothesized environmental risk factors and their interaction with rheumatoid arthritis (RA). METHODS: Four hundred patients recently diagnosed with RA and 400 controls frequency-matched by gender and birth year using Propensity Score Matching (PSM) were selected from northern China. Investigation was performed using self-reported data from interviewer-administered surveys. Associations between exposure variables and risk of RA were evaluated using multifactor non-conditional logistic regression...
April 11, 2017: Modern Rheumatology
https://www.readbyqxmd.com/read/28366409/demographic-lifestyle-and-other-factors-in-relation-to-antim%C3%A3-llerian-hormone-levels-in-mostly-late-premenopausal-women
#2
Seungyoun Jung, Naomi Allen, Alan A Arslan, Laura Baglietto, Louise A Brinton, Brian L Egleston, Roni Falk, Renée T Fortner, Kathy J Helzlsouer, Annika Idahl, Rudolph Kaaks, Eva Lundin, Melissa Merritt, Charlotte Onland-Moret, Sabina Rinaldi, María-José Sánchez, Sabina Sieri, Helena Schock, Xiao-Ou Shu, Patrick M Sluss, Paul N Staats, Ruth C Travis, Anne Tjønneland, Antonia Trichopoulou, Shelley Tworoger, Kala Visvanathan, Vittorio Krogh, Elisabete Weiderpass, Anne Zeleniuch-Jacquotte, Wei Zheng, Joanne F Dorgan
OBJECTIVE: To identify reproductive, lifestyle, hormonal, and other correlates of circulating antimüllerian hormone (AMH) concentrations in mostly late premenopausal women. DESIGN: Cross-sectional study. SETTING: Not applicable. PATIENT(S): A total of 671 premenopausal women not known to have cancer. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Concentrations of AMH were measured in a single laboratory using the picoAMH ELISA...
April 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28362019/non-genetic-risk-factors-for-early-and-late-age-at-menarche-in-eastern-ukrainian-females
#3
Anna Yermachenko, Iryna Mogilevkina, Vitaliy G Gurianov, Olena Getsko, Volodymyr Dvornyk
BACKGROUND: Age at menarche is a reproductive trait, which is largely influenced by environmental factors. Each population has a set of lifestyle factors that may shift age at menarche in different direction. Populations of Eastern Slavs, particularly Ukrainians, are underrepresented in studies of reproductive health. The objective of the present research was to determine important non-genetic risk factors, which may contribute to menarcheal onset in Eastern Ukrainians. METHODS: In total 620 females aged 17-25 years participated in the cross-sectional survey...
January 26, 2017: Anthropologischer Anzeiger; Bericht über die Biologisch-anthropologische Literatur
https://www.readbyqxmd.com/read/28350418/hymen-imperforatus-%C3%A3-r-en-diagnos-som-ofta-missas-risk-f%C3%A3-r-l%C3%A3-ngdragna-symtom-om-adekvat-unders%C3%A3-kning-inte-genomf%C3%A3-rs
#4
Martin Salö, Anna Börjesson
Imperforate hymen - an often missed diagnosis Imperforate hymen is the most common congenital malformation in the female reproduction system that give rise to obstructive symptoms. If the diagnosis is not made in the newborn girl, symptoms often first arise at menarche. The diagnosis is easy to make but has to be suspected. This case reports describes the typical clinical picture of a late diagnosed imperforate hymen. As shown in this case and from a review of the literature, these girls often have symptoms for a long time before the diagnosis is made...
March 23, 2017: Läkartidningen
https://www.readbyqxmd.com/read/28338576/genetic-polymorphism-of-nucks1-is-associated-with-the-susceptibility-of-adolescent-idiopathic-scoliosis
#5
Leilei Xu, Chao Xia, Weixiang Sun, Xiaodong Qin, Yong Qiu, Zezhang Zhu
STUDY DESIGN: A genetic association study. OBJECTIVE: To investigate whether NUCKS1 is a susceptible gene of adolescent idiopathic scoliosis (AIS) in Chinese population and to further narrate its association with the clinical phenotypes. SUMMARY OF BACKGROUND DATA: AIS is characterized by late onset of menarche and disturbed growth rhythm. Previous studies showed that NUCKS1 is associated with age at menarche and pubertal height growth. METHODS: SNP rs951366 of NUCKS1 was genotyped in 972 patients and 1454 healthy controls...
March 23, 2017: Spine
https://www.readbyqxmd.com/read/28293690/bone-mineral-density-among-korean-females-aged-20-50%C3%A2-years-influence-of-age-at-menarche-the-korea-national-health-and-nutrition-examination-survey-2008-2011
#6
H K Chang, D-G Chang, J-P Myong, J-H Kim, S-J Lee, Y S Lee, H-N Lee, K H Lee, D C Park, C J Kim, S Y Hur, J S Park, T C Park
To evaluate a possible correlation between bone mineral density (BMD) and age at menarche, the present study used the BMD dataset of the Korea National Health and Nutrition Examination Survey IV-V (KNHANES IV-V). Age at menarche had a small but significant association with BMD of the lumbar spine in premenopausal Korean females, aged 20-50 years. INTRODUCTION: To investigate any correlation between bone mineral density (BMD) and age at menarche in Korean females using data from the fourth and fifth Korea National Health and Nutrition Examination Survey (KNHANES IV-V; 2008-2011)...
March 14, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28264686/reproductive-risk-factors-associated-with-breast-cancer-in-women-in-bangui-a-case-control-study
#7
Augustin Balekouzou, Ping Yin, Christian Maucler Pamatika, Cavin Epie Bekolo, Sylvain Wilfrid Nambei, Marceline Djeintote, Komlan Kota, Christian Diamont Mossoro-Kpinde, Chang Shu, Minghui Yin, Zhen Fu, Tingting Qing, Mingming Yan, Jianyuan Zhang, Shaojun Chen, Hongyu Li, Zhongyu Xu, Boniface Koffi
BACKGROUND: Breast cancer (breast Ca) is recognised as a major public health problem in the world. Data on reproductive factors associated with breast Ca in the Central African Republic (CAR) is very limited. This study aimed to identify reproductive variables as risk factors for breast Ca in CAR women. METHODS: A case-control study was conducted among 174 cases of breast Ca confirmed at the Pathology Unit of the National Laboratory in Bangui between 2003 and 2015 and 348 age-matched controls...
March 6, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/28182101/periductal-mastitis-an-inflammatory-disease-related-to-bacterial-infection-and-consequent-immune-responses
#8
Lu Liu, Fei Zhou, Pin Wang, Lixiang Yu, Zhongbing Ma, Yuyang Li, Dezong Gao, Qiang Zhang, Liang Li, Zhigang Yu
Periductal mastitis (PDM) is a prolonged inflammatory disease, but the cause of PDM is poorly understood. In the present case control study, 87 PDM and 87 healthy controls were enrolled and the results were evaluated to identify the significant risk factors for PDM. To investigate the roles of bacterial infection and critical cytokines expression, 16S rRNA gene sequencing and bacterial culturing were conducted. We also measured the levels of interferon-γ, interleukin-12A, and interleukin-17A by semiquantitative immunohistochemistry method...
2017: Mediators of Inflammation
https://www.readbyqxmd.com/read/28142040/bmi-reproductive-factors-and-breast-cancer-molecular-subtypes-a-case-control-study-and-meta-analysis
#9
Hui Li, Xuezheng Sun, Erline Miller, Qiong Wang, Ping Tao, Li Liu, Ying Zhao, Mengjie Wang, Yana Qi, Jiayuan Li
BACKGROUND: The effects of body mass index (BMI) and reproductive factors may vary among breast cancer molecular subtypes, evidence of which is lacking in East Asia. METHODS: From 2002 to 2010, 1256 breast cancer patients and 1416 healthy women were recruited. Anthropometric and reproductive factors were collected from medical charts. Breast cancer subtype was defined by ER, PR, and HER2 status. Polytomous logistic regression was used to evaluate associations between risk factors and breast cancer subtypes, with subgroup analysis by menopausal status...
April 2017: Journal of Epidemiology
https://www.readbyqxmd.com/read/28118209/menstrual-and-reproductive-factors-in-the-risk-of-thyroid-cancer-in-japanese-women-the-japan-public-health-center-based-prospective-study
#10
Sangah Shin, Norie Sawada, Eiko Saito, Taiki Yamaji, Motoki Iwasaki, Taichi Shimazu, Shizuka Sasazuki, Manami Inoue, Shoichiro Tsugane
The aim of this study was to evaluate the associations between menstrual and reproductive factors and thyroid cancer risk among Japanese women. A total 54 776 women aged 40-69 years completed a self-administered questionnaire, which included menstrual and reproductive history. During 1990-2012, 187 newly diagnosed cases of thyroid cancer were identified. Hazard ratios (HRs) and 95% confidence intervals (CIs) for menstrual and reproductive factors and incidence of thyroid cancer were estimated using Cox proportional hazards regression...
January 21, 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28086982/reproductive-factors-and-the-risk-of-triple-negative-breast-cancer-in-white-women-and-african-american-women-a-pooled-analysis
#11
Huiyan Ma, Giske Ursin, Xinxin Xu, Eunjung Lee, Kayo Togawa, Lei Duan, Yani Lu, Kathleen E Malone, Polly A Marchbanks, Jill A McDonald, Michael S Simon, Suzanne G Folger, Jane Sullivan-Halley, Dennis M Deapen, Michael F Press, Leslie Bernstein
BACKGROUND: Early age at menarche, nulliparity, late age at first completed pregnancy, and never having breastfed, are established breast cancer risk factors. However, among breast cancer subtypes, it remains unclear whether all of these are risk factors for triple-negative breast cancer (TNBC). METHODS: We evaluated the associations of these reproductive factors with TNBC, in 2658 patients with breast cancer (including 554 with TNBC) and 2448 controls aged 20-64 years, who participated in one of the three population-based case-control studies: the Women's Contraceptive and Reproductive Experiences Study, the Women's Breast Carcinoma in situ Study, or the Women's Learning the Influence of Family and Environment Study...
January 13, 2017: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/27996108/effect-of-reproductive-history-and-exogenous-hormone-use-on-cognitive-function-in-mid-and-late-life
#12
Roksana Karim, Ha Dang, Victor W Henderson, Howard N Hodis, Jan St John, Roberta D Brinton, Wendy J Mack
OBJECTIVES: To investigate the association between reproductive history indicators of hormonal exposure, including reproductive period, pregnancy, and use of hormonal contraceptives, and mid- and late-life cognition in postmenopausal women. DESIGN: Analysis of baseline data from two randomized clinical trials: the Women's Isoflavone Soy Health and the Early vs Late Intervention Trial of Estradiol. SETTING: University academic research center...
December 2016: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27919437/fertile-lifespan-characteristics-and-all-cause-and-cause-specific-mortality-among-postmenopausal-women-the-rotterdam-study
#13
Loes Jaspers, Maryam Kavousi, Nicole S Erler, Albert Hofman, Joop S E Laven, Oscar H Franco
OBJECTIVE: To characterize the relation between established and previously unexplored characteristics of the fertile life with all-cause and cause-specific mortality. DESIGN: Prospective cohort study. SETTING: Not applicable. PATIENT(S): A total of 4,076 postmenopausal women. INTERVENTION(S): Women's fertile lifespan (age at menarche to menopause), number of children, maternal age at first and last child, maternal lifespan (interval between maternal age at first and last child), postmaternal fertile lifespan (interval between age at last child and menopause), lifetime cumulative number of menstrual cycles, and unopposed cumulative endogenous estrogen (E) exposure...
February 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/27880720/the-impact-of-reproductive-life-on-breast-cancer-risk-in-women-with-family-history-or-brca-mutation
#14
Angela Toss, Giovanni Grandi, Angelo Cagnacci, Luigi Marcheselli, Silvia Pavesi, Elisabetta De Matteis, Elisabetta Razzaboni, Chiara Tomasello, Stefano Cascinu, Laura Cortesi
Reproductive history and exogenous hormonal exposures are acknowledged risk factors for breast cancer in the general population. In women at increased breast cancer risk for genetic predisposition or positive family history, data regarding these risk factors are limited or conflicting, and recommendations for these categories are unclear. We evaluated the characteristics of reproductive life in 2522 women at increased genetic or familial breast cancer risk attending our Family Cancer Center. Breast cancers in BRCA mutation carriers were more likely to be hormone receptor negative, diagnosed at 35 years or before and multiple during the lifetime than tumors in women at increased familial risk, while the distribution of invasive cancers and HER2 positive tumors was similar in the different risk groups...
February 7, 2017: Oncotarget
https://www.readbyqxmd.com/read/27836305/age-at-menarche-and-risk-of-major-cardiovascular-diseases-evidence-of-birth-cohort-effects-from-a-prospective-study-of-300-000-chinese-women
#15
Ling Yang, Liming Li, Iona Y Millwood, Sanne A E Peters, Yiping Chen, Yu Guo, Zheng Bian, Xiaofang Chen, Lingli Chen, Shixian Feng, Silu Lv, Zhigang Pang, Mark Woodward, Zhengming Chen
BACKGROUND: Previous studies of mostly Western women have reported inconsistent findings on the association between age at menarche and risk of cardiovascular disease (CVD). Little is known about the association in China where there has been a large intergenerational decrease in women's mean age at menarche. METHODS: The China Kadoorie Biobank recruited 302,632 women aged 30-79 (mean 50.5)years in 2004-8 from 10 diverse regional sites across China. During 7years follow-up, 14,111 incident cases of stroke, 14,093 of coronary heart disease (CHD), and 3200 CVD deaths were reported among 281,491 women who had no prior history of CVD at baseline...
January 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/27780981/longitudinal-observation-of-serum-anti-m%C3%A3-llerian-hormone-in-three-girls-after-cancer-treatment
#16
Yoko Miyoshi, Kie Yasuda, Makiko Tachibana, Hisao Yoshida, Emiko Miyashita, Takako Miyamura, Yoshiko Hashii, Kae Hashimoto, Tadashi Kimura, Keiichi Ozono
Gonadal dysfunction and infertility are major endocrinological late effects among childhood cancer survivors. Chemotherapy and radiation have gonadotoxic effects and diminish the ovarian reserve. The serum concentration of anti-Müllerian hormone (AMH) is a useful marker of ovarian reserve in survivors. We conducted a longitudinal study to investigate the variations of AMH in evaluating the acute and chronic effects of cancer therapy on the ovary. Three young female patients with different hematological diseases were registered, and their medical records were reviewed...
October 2016: Clinical Pediatric Endocrinology: Case Reports and Clinical Investigations: Official Journal of the Japanese Society for Pediatric Endocrinology
https://www.readbyqxmd.com/read/27737576/changes-in-clavicle-length-and-maturation-in-americans-1840-1980
#17
Natalie R Langley, Sandra Cridlin
Secular changes refer to short-term biological changes ostensibly due to environmental factors. Two well-documented secular trends in many populations are earlier age of menarche and increasing stature. This study synthesizes data on maximum clavicle length and fusion of the medial epiphysis in 1840-1980 American birth cohorts to provide a comprehensive assessment of developmental and morphological change in the clavicle. Clavicles from the Hamann-Todd Human Osteological Collection (n = 354), McKern and Stewart Korean War males (n = 341), Forensic Anthropology Data Bank (n = 1,239), and the McCormick Clavicle Collection (n = 1,137) were used in the analysis...
January 2016: Human Biology
https://www.readbyqxmd.com/read/27699734/-overview-of-endometrial-cancer
#18
Chia-Chun Li, Tsui-Hsia Feng
Endometrial cancer is the most common gynecological cancer and the sixth most common cancer among women in Taiwan. Risk factors for endometrial cancer include obesity, long-term estrogen replacement therapy, diabetes mellitus, hypertension, nulliparty, early age at menarche, late age at menopause, and tamoxifen therapy. Most women with endometrial cancer exhibit abnormal uterine bleeding. Endometrial cancer is often diagnosed at stage I. Surgery alone is the primary treatment for stage I endometrial cancer...
October 2016: Hu Li za Zhi the Journal of Nursing
https://www.readbyqxmd.com/read/27696903/early-pubertal-timing-is-common-among-adolescent-girl-to-boy-sex-reassignment-applicants
#19
Maria Sumia, Nina Lindberg, Marja Työläjärvi, Riittakerttu Kaltiala-Heino
OBJECTIVES: The aim of our study was to explore whether gender dysphoria in adolescent girls is associated with early pubertal timing. METHODS: We compared menarcheal timing among 52 adolescent girl-to-boy sex reassignment (SR) applicants with that of 644 adolescent girls who participated in an adolescent population mental health survey. RESULTS: Of the population girls, 21% presented with early (≤11 years), 61% with normative (12-13 years) and 19% with late (≥14 years) menarcheal timing; among the SR applicants, 42% presented with early, 46% with normative and 12% with late menarcheal timing (p = 0...
December 2016: European Journal of Contraception & Reproductive Health Care
https://www.readbyqxmd.com/read/27692528/pediatric-idiopathic-intracranial-hypertension-age-gender-and-anthropometric-features-at-diagnosis-in-a-large-retrospective-multisite-cohort
#20
Claire A Sheldon, Grace L Paley, Rui Xiao, Anat Kesler, Ori Eyal, Melissa W Ko, Chantal J Boisvert, Robert A Avery, Vincenzo Salpietro, Paul H Phillips, Gena Heidary, Shana E McCormack, Grant T Liu
PURPOSE: To examine anthropometric and maturational characteristics at diagnosis in pediatric idiopathic intracranial hypertension (IIH). DESIGN: Retrospective, international, multisite study. PARTICIPANTS: Pediatric patients (2-18 years of age at diagnosis) with IIH. MAIN OUTCOME MEASURES: Body mass index (BMI), height, and weight Z-scores; sexual maturation. METHODS: Cases of IIH were identified retrospectively based on diagnostic code, pediatric neuro-ophthalmologist databases, or both and updated diagnostic criteria (2013) were applied to confirm definite IIH...
November 2016: Ophthalmology
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