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https://www.readbyqxmd.com/read/30021411/prevalence-of-human-cosavirus-and-saffold-virus-in-young-children-with-gastroenteritis-northern-italy
#1
Valentina Daprà, Paola Montanari, Marco Rassu, Cristina Calvi, Ilaria Galliano, Massimiliano Bergallo
BACKGROUND: Gastroenteritis is a common disease in children, characterized by diarrhea, vomiting, abdominal pain, and fever. Human Cosavirus (HCoSV) and Saffold virus (SAFV) both have a worldwide distribution. Both viruses have been detected in the stools of patients with acute gastroenteritis in several countries. METHODS: In order to provide more insights into the epidemiology of enteric viruses that are not included usually in routine diagnostic tests, cases of childhood sporadic gastroenteritis of unknown etiology requiring hospital admission in Turin, Italy, during December 2014 to November 2015, were screened for HCoSV and SAFV...
July 18, 2018: Minerva Pediatrica
https://www.readbyqxmd.com/read/30018230/immunogenicity-and-induction-of-functional-antibodies-in-rabbits-immunized-with-a-trivalent-typhoid-invasive-nontyphoidal-salmonella-glycoconjugate-formulation
#2
Scott M Baliban, Jessica C Allen, Brittany Curtis, Mohammed N Amin, Andrew Lees, R Nageswara Rao, Gangadhara Naidu, Ramasamy Venkatesan, D Yogeswara Rao, Vadrevu Krishna Mohan, Krishna M Ella, Myron M Levine, Raphael Simon
Typhoid fever due to Salmonella Typhi and invasive nontyphoidal Salmonella (iNTS) infections caused by serovars Enteritidis (SE) and Typhimurium (STm) are major pediatric health problems in sub-Saharan Africa. Typhoid has high complication rates, and iNTS infections have high case fatality rates; moreover, emerging antimicrobial resistance is diminishing treatment options. Vi capsule-based typhoid conjugate vaccine (Typbar-TCV™), licensed in India and pre-qualified by the World Health Organization, elicits durable immunity when administered to infants, but no iNTS vaccines are licensed or imminent...
July 17, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/30009667/neonatal-onset-fam%C3%A4-l%C3%A4-al-med%C3%A4-terranean-fever
#3
Elif Çelikel, Z Birsin Özçakar, Semanur Özdel, Nilgün Çakar, Fatma Aydın, Seda Şahin, Fatoş Yalçınkaya
OBJECTIVES: Familial Mediterranean fever (FMF) is an autosomal recessive disease characterised by recurrent, self limited attacks of fever with serositis. Recently, it was shown that FMF patients with early disease onset have more severe disease. The aim of this study was to describe the demographic, clinical and genetic features of FMF patients who had disease onset during the neonatal period. METHODS: Medical records of all patients diagnosed as FMF and had been seen in the outpatient clinic of Pediatric Rheumatology department between January 2013-January 2014 were retrospectively evaluated...
July 14, 2018: Modern Rheumatology
https://www.readbyqxmd.com/read/30008140/impact-of-balloon-laryngoplasty-on-management-of-acute-subglottic-stenosis
#4
Andréia Melchiors Wenzel, Cláudia Schweiger, Denise Manica, Leo Sekine, Isabel Cristina Schütz Ferreira, Gabriel Kuhl, Paulo José Cauduro Marostica
PURPOSE: To assess the impact of balloon laryngoplasty on clinical and surgical outcomes in pediatric patients with acute subglottic stenosis. METHODS: Two case series were included and compared. The first group included patients treated initially either with tracheostomy (if severe symptoms) or with close follow-up (if mild symptoms). Those children underwent re-evaluation and specific treatment of their stenosis with laser incisions or open surgeries some weeks later...
July 14, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/30006648/pituitary-gland-and-bone-involvement-of-langerhans-cell-histiocytosis-in-a-boy-and-brief-review-of-the-literature
#5
Chao Miao, Lei Zhang, Ming Sun, Chao Ma
A 3 years old boy was hospitalized with a month's history of polydipsia, polyuria and low fever. There was no relevant family history. This is a rare case of Langerhans cell histiocytosis (LCH) with both bone and pituitary infiltration shown on the technetium-99m methylene diphosphonate (99m Tc-MDP) scan and brain magnetic resonance imaging (MRI). Sagittal and coronal T1-weighted images on MRI showed the typical lack of high signal intensity of the posterior pituitary which corresponded to the central signs of diabetes insipidus (DI)...
July 12, 2018: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/29998580/cerebrospinal-fluid-non-pleocytosis-in-pediatric-enteroviral-meningitis-a-large-scale-review
#6
Ji Yeon Song, Sang Ook Nam, Young A Kim, Kyung Min Kim, Soo Young Lyu, Ara Ko, Young Mi Kim, Gyu Min Yeon, Yun-Jin Lee
BACKGROUND: Lack of cerebrospinal fluid (CSF) pleocytosis has been reported in some children of enteroviral meningitis (EVM). The aim of this paper is to investigate the clinical spectrum and related factors for EVM with CSF non-pleocytosis. METHODS: The authors retrospectively reviewed the databases of children diagnosed with EVM by CSF polymerase chain reaction testing between 2011 and 2014. CSF pleocytosis was defined at each age by the criteria. Clinical and laboratory variables were compared between patients with CSF pleocytosis and non-pleocytosis...
July 11, 2018: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/29997076/traditional-uvulectomy-a-common-practice-in-south-kivu-in-the-democratic-republic-of-congo
#7
R Mbusa Kambale, Y Balibuno, N Isia Francisca, J Bwija Kasengi, G Fatuma Mayele, B Mungo Masumbuko
BACKGROUND: Traditional uvulectomy in children, a very common and dangerous practice, remains poorly documented in the Democratic Republic of Congo (DRC). The aim of this study was to establish the epidemiological and clinical profile of children after a traditional uvulectomy and to determine their outcome of the children after this practice in 2 pediatric emergency unities in South Kivu province, DRC. METHOD: This was a cross-sectional study took place conducted in 2 pediatric emergency unities in Bukavu town, in South Kivu province, throughout from January to December 2016...
May 1, 2018: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/29996185/-phenotype-study-of-scn2a-gene-related-epilepsy
#8
Q Zeng, Y H Zhang, X L Yang, J Zhang, A J Liu, X Y Liu, Y W Jiang, X R Wu
Objective: To summarize the phenotype of epileptic children with SCN2A mutations. Methods: Epileptic patients who were treated in the Pediatric Department of Peking University First Hospital from September 2006 to October 2017 and detected with SCN2A mutations by targeted next-generation sequencing were enrolled. Clinical manifestations of all patients were analyzed retrospectively. Results: A total of 21 patients (16 boys and 5 girls) with SCN2A mutations were collected. Twenty-one SCN2A mutations were identified...
July 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29995142/clinical-and-epidemiological-characteristics-and-survival-outcomes-of-children-with-neuroblastoma-21-years-of-experience-at-the-instituto-de-oncologia-pedi%C3%A3-trica-in-s%C3%A3-o-paulo-brazil
#9
Januária Nunes Lucena, Maria Teresa Seixas Alves, Simone Campos Vieira Abib, Gabriel Oliveira de Souza, Regina Pukenis de Castro Neves, Eliana Maria Monteiro Caran
OBJECTIVE: To describe the clinical and epidemiological characteristics and survival outcomes of children with neuroblastoma (NB) treated at a pediatric oncology center from 1991 to 2012. METHODS: A retrospective study with clinical and epidemiological data from 258 patients with neuroblastoma treated at a pediatric oncology center from 1991 to 2012, using medical records. RESULTS: The average age of the children at diagnosis was 40.5±46...
July 10, 2018: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
https://www.readbyqxmd.com/read/29990410/a-masquerader-of-disease-an-incomplete-presentation-of-kawasaki-disease
#10
Josh Rezkalla, Peter Chang, Elizabeth Peck, Michelle Schimelpfenig
Kawasaki disease (KD) is a systemic pediatric vasculitis that most commonly affects children between the ages of 6 months and 4 years. The diagnosis of KD requires a high degree of clinical suspicion. In younger patients (less than 6 months) the diagnosis is exceedingly difficult as these patients typically do not meet the criteria to diagnosis KD clinically. Oftentimes, these younger patients do not meet enough of the criteria to warrant ordering an echocardiogram. We report a case of a 6-month-old Caucasian female who presented with high fevers originally thought to be due to a urinary tract infection...
February 2018: South Dakota Medicine: the Journal of the South Dakota State Medical Association
https://www.readbyqxmd.com/read/29986981/decreasing-low-acuity-pediatric-emergency-room-visits-with-increased-clinic-access-and-improved-parent-education
#11
Toren Davis, Albert Meyer, Janalynn Beste, Sonali Batish
BACKGROUND AND OBJECTIVE: The goal of this study was to decrease avoidable, low-acuity emergency department (ED) use among pediatric patients at Coastal Family Medicine. The rationale behind this focus was to improve continuity for our patients while decreasing the cost burden for low-acuity ED visits. The family medicine residency clinic pediatric panel has grown by 35% over the past 3 years, bringing this issue of same-day acute access in our clinic to the forefront. METHODS: A survey was created to better understand the needs of our high users of the ED...
July 2018: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/29986729/private-retail-drug-shops-what-they-are-how-they-operate-and-implications-for-health-care-delivery-in-rural-uganda
#12
Chrispus Mayora, Freddy Eric Kitutu, Ngianga-Bakwin Kandala, Elizabeth Ekirapa-Kiracho, Stefan Swartling Peterson, Henry Wamani
BACKGROUND: Retail drug shops play a significant role in managing pediatric fevers in rural areas in Uganda. Targeted interventions to improve drug seller practices require understanding of the retail drug shop market and motivations that influence practices. This study aimed at describing the operational environment in relation to the Uganda National Drug Authority guidelines for setup of drug shops; characteristics, and dispensing practices of private retail drug shops in managing febrile conditions among under-five children in rural western Uganda...
July 9, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29986368/-otitis-media-definition-pathogenesis-clinical-presentation-diagnosis-and-therapy
#13
A Leichtle, T K Hoffmann, M C Wigand
A number of diseases of the middle ear are summed up under the term otitis media: acute otitis media, recurrent acute otitis media, otitis media with effusion, chronic suppurative otitis media and chronic otitis media epitympanalis (= cholesteatoma). Acute otitis media belongs to the most common pediatric diseases and is often caused by bacterial infection. Since the advent of pneumococcal vaccines the quantity of AOM caused by pneumococci has declined; vaccination against NTHi and Moraxella catarrhalis are being developed...
July 2018: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/29970110/kawasaki-disease-in-the-neonate-case-report-and-literature-review
#14
Fajer Altammar, Bianca Lang
BACKGROUND: Kawasaki Disease (KD), the leading cause of acquired heart disease in children in the developed world, is extremely rare in neonates. We present a case of incomplete KD in a neonate and a review of the literature on neonatal KD. CASE PRESENTATION: A previously healthy full term 15 day old Caucasian male with an unremarkable antenatal and perinatal history, presented on Day 2 of illness with fever, rash, irritability, and poor feeding. Examination revealed fever (39...
July 3, 2018: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/29963408/an-evidence-based-approach-to-evaluation-and-management-of-the-febrile-child-in-indian-emergency-department
#15
REVIEW
Prerna Batra, Neha Thakur, Prashant Mahajan, Reena Patel, Narendra Rai, Nitin Trivedi, Bernhard Fassl, Binita Shah, Abhijeet Saha, Marie Lozon, Rockefeller A Oteng, Dheeraj Shah, Sagar Galwankar
Fever is the most common complaint for a child to visit hospital. Under the aegis of INDO-US Emergency and Trauma Collaborative, Pediatric Emergency Medicine chapter of Academic College of Emergency Experts in India developed evidence-based consensus for evaluation and management of febrile child in emergency department. An extensive literature search and further online communication of the group led to the development of a detailed approach for the evaluation and management of individual conditions associated with fever...
April 2018: International Journal of Critical Illness and Injury Science
https://www.readbyqxmd.com/read/29957729/pediatric-amazonian-toxoplasmosis-caused-by-atypical-strains-in-french-guiana-2002-2017
#16
Romain Blaizot, Cécile Nabet, Denis Blanchet, Elise Martin, Aurélien Mercier, Marie-Laure Dardé, Narcisse Elenga, Magalie Demar
BACKGROUND: Amazonian toxoplasmosis is a recently described form of Toxoplasma gondii infection, characterized by severe clinical and biological features, and involvement of atypical genetic strains circulating through a forest-based cycle. Though mostly reported in French Guiana since 1998, this disease is probably under-diagnosed in other areas of South America. Few data are available on its specific features in children. METHODS: We retrospectively included all children seen in Cayenne between 2002 and 2017, diagnosed with acute toxoplasmosis due to an atypical strain...
June 27, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29953028/an-assessment-of-a-pediatric-early-warning-system-score-in-severe-hand-foot-and-mouth-disease-children-to-detect-clinical-deterioration-in-hospitalized-children
#17
Lu Mei, Xin Song, Yan Kong, Guiling Yu
Identification of deteriorating severe hand, foot, and mouth disease (HFMD) children for referral to intensive care remains problematic.The medical records of 2382 hospitalized children with severe HFMD from May 2013 to September 2015 were retrospectively reviewed. A Pediatric Early Warning System (PEWS) score was designed based on study parameters on admission, evaluated in a logistic regression model, and subsequently validated with different cut-off scores, to predict the risk for clinical deterioration...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29938303/intramedullary-cervical-abscess-mimicking-a-spinal-cord-tumor-in-a-10-year-old-girl-a-case-based-review
#18
REVIEW
Exequiel Patricio Verdier, Omar Konsol, Santiago Portillo
BACKGROUND: Intramedullary spinal cord abscesses (ISCA) are a rare pathological entity with very few cases reported in the world and may be confused with an intramedullary tumor. Cervical location is the least frequently affected, except for cryptogenic spread, mostly seen in adult patients. Meticulous study of contrast-enhanced MRI pictures has a key role in the diagnosis. METHOD AND RESULTS: We present a case of a spontaneous cervical ISCA, mimicking a spinal cord tumor, in a pediatric patient with good outcome...
June 24, 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29935535/the-antipyretic-efficacy-and-safety-of-propacetamol-compared-with-dexibuprofen-in-febrile-children-a-multicenter-randomized-double-blind-comparative-phase-3-clinical-trial
#19
Seung Jun Choi, Sena Moon, Ui Yoon Choi, Yoon Hong Chun, Jung Hyun Lee, Jung Woo Rhim, Jin Lee, Hwang Min Kim, Dae Chul Jeong
BACKGROUND: We aimed to compare the antipyretic efficacy, safety, and tolerability between oral dexibuprofen and intravenous propacetamol in children with upper respiratory tract infection (URTI) presenting with fever. METHODS: Patients aging from 6 months to 14 years admitted for URTI with axillary body temperature ≥ 38.0 °C were enrolled and randomized into the study or control group. Patients in the study group were intravenously infused with propacetamol and subsequently oral placebo medication was administered...
June 23, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29930928/prevalence-of-fungemia-in-pediatric-patients-with-febrile-neutropenia
#20
Mohsen Meidani, Masoome Baniasadi, Farzin Khorvash
Background: Increasing use of different chemotherapy regimens, organ transplants, etc., has led to the increasing number of neutropenic patients. Overall, 10% of patients affected by cancer who are under treatment with anticancer drugs, regardless of the tumor type, are susceptible to febrile neutropenia. The study was performed to evaluate the frequency of bloodstream fungal infections in pediatric patients with febrile neutropenia in Sayed Al-Shohada Hospital (Cancer Referral Center in Isfahan) in 2010-2012...
2018: Advanced Biomedical Research
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