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https://www.readbyqxmd.com/read/29666750/tweet-success-scientific-communication-correlates-with-increased-citations-in-ecology-and-conservation
#1
Clayton T Lamb, Sophie L Gilbert, Adam T Ford
Science communication is seen as critical for the disciplines of ecology and conservation, where research products are often used to shape policy and decision making. Scientists are increasing their online media communication, via social media and news. Such media engagement has been thought to influence or predict traditional metrics of scholarship, such as citation rates. Here, we measure the association between citation rates and the Altmetric Attention Score-an indicator of the amount and reach of the attention an article has received-along with other forms of bibliometric performance (year published, journal impact factor, and article type)...
2018: PeerJ
https://www.readbyqxmd.com/read/29664963/trpv4-inhibition-attenuates-stretch-induced-inflammatory-cellular-responses-and-lung-barrier-dysfunction-during-mechanical-ventilation
#2
N Pairet, S Mang, G Fois, M Keck, M Kühnbach, J Gindele, M Frick, P Dietl, D J Lamb
Mechanical ventilation is an important tool for supporting critically ill patients but may also exert pathological forces on lung cells leading to Ventilator-Induced Lung Injury (VILI). We hypothesised that inhibition of the force-sensitive transient receptor potential vanilloid (TRPV4) ion channel may attenuate the negative effects of mechanical ventilation. Mechanical stretch increased intracellular Ca2+ influx and induced release of pro-inflammatory cytokines in lung epithelial cells that was partially blocked by about 30% with the selective TRPV4 inhibitor GSK2193874, but nearly completely blocked with the pan-calcium channel blocker ruthenium red, suggesting the involvement of more than one calcium channel in the response to mechanical stress...
2018: PloS One
https://www.readbyqxmd.com/read/29660848/international-collaborative-study-to-assess-cardiovascular-risk-and-evaluate-long-term-health-in-cats-with-preclinical-hypertrophic-cardiomyopathy-and-apparently-healthy-cats-the-reveal-study
#3
Philip R Fox, Bruce W Keene, Kenneth Lamb, Karsten A Schober, Valerie Chetboul, Virginia Luis Fuentes, Gerhard Wess, Jessie Rose Payne, Daniel F Hogan, Alison Motsinger-Reif, Jens Häggström, Emilie Trehiou-Sechi, Deborah M Fine-Ferreira, Reid K Nakamura, Pamela M Lee, Manreet K Singh, Wendy A Ware, Jonathan A Abbott, Geoffrey Culshaw, Sabine Riesen, Michele Borgarelli, Michael B Lesser, Nicole Van Israël, Etienne Côté, John E Rush, Barret Bulmer, Roberto A Santilli, Andrea C Vollmar, Maribeth J Bossbaly, Nadine Quick, Claudio Bussadori, Janice M Bright, Amara H Estrada, Dan G Ohad, Maria Josefa Fernández-Del Palacio, Jenifer Lunney Brayley, Denise S Schwartz, Christina M Bové, Sonya G Gordon, Seung Woo Jung, Paola Brambilla, N Sydney Moïse, Christopher D Stauthammer, Rebecca L Stepien, Cecilia Quintavalla, Christophe Amberger, Ferenc Manczur, Yong-Wei Hung, Remo Lobetti, Marie De Swarte, Alice Tamborini, Carmel T Mooney, Mark A Oyama, Andrey Komolov, Yoko Fujii, Romain Pariaut, Masami Uechi, Victoria Yukie Tachika Ohara
BACKGROUND: Hypertrophic cardiomyopathy is the most prevalent heart disorder in cats and principal cause of cardiovascular morbidity and mortality. Yet, the impact of preclinical disease is unresolved. HYPOTHESIS/OBJECTIVES: Observational study to characterize cardiovascular morbidity and survival in cats with preclinical nonobstructive (HCM) and obstructive (HOCM) hypertrophic cardiomyopathy and in apparently healthy cats (AH). ANIMALS: One thousand seven hundred and thirty client-owned cats (430 preclinical HCM; 578 preclinical HOCM; 722 AH)...
April 16, 2018: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/29660626/tubulin-posttranslational-modifications-in-in-vitro-matured-prepubertal-and-adult-ovine-oocytes
#4
E Serra, S Succu, F Berlinguer, C Porcu, G G Leoni, S Naitana, S D Gadau
Microtubules (MTs), polymers of alpha/beta-tubulin heterodimers, are involved in crucial functions in eukaryotic cells. MTs physiology can be influenced by a variety of post-translational modifications (PTMs), including tyrosination, detyrosination, delta 2 modification, acetylation, polyglutamylation, polyglycylation. In mammalian oocytes, MTs are essential for meiosis, regulating the formation of meiotic spindle and chromosomes movements. Considering that the patterns of tubulin PTMs (tyrosination, detyrosination, acetylation, polyglutamylation and delta 2 modification) have not been investigated in ovine oocytes, this study has been designed to investigate their presence and quantification in in vitro matured (IVM) adult and prepubertal ovine oocytes...
April 7, 2018: Theriogenology
https://www.readbyqxmd.com/read/29659625/st-waveform-analysis-for-monitoring-hypoxic-distress-in-fetal-sheep-after-prolonged-umbilical-cord-occlusion
#5
Peter Andriessen, Alex Zwanenburg, Judith O E H van Laar, Rik Vullings, Ben J M Hermans, Hendrik J Niemarkt, Reint K Jellema, Daan R M G Ophelders, Tim G A M Wolfs, Boris W Kramer, Tammo Delhaas
INTRODUCTION: The inconclusive clinical results for ST-waveform analysis (STAN) in detecting fetal hypoxemia may be caused by the signal processing of the STAN-device itself. We assessed the performance of a clinical STAN device in signal processing and in detecting hypoxemia in a fetal sheep model exposed to prolonged umbilical cord occlusion (UCO). METHODS: Eight fetal lambs were exposed to 25 minutes of UCO. ECG recordings were analyzed during a baseline period and during UCO...
2018: PloS One
https://www.readbyqxmd.com/read/29657413/genetic-parameter-estimation-for-pre-weaning-growth-traits-in-jordan-awassi-sheep
#6
Khaleel Jawasreh, Zuhair Bani Ismail, Feizal Iya, Vielka Jeanethe Castañeda-Bustos, Mauricio Valencia-Posadas
Aim: The aim of this study was to estimate the heritability, genetic and phenotypic correlations, and the genetic trends for pre-weaning growth traits including the birth weight (BWT), weaning weight (WWT), pre-weaning daily gain (PWDG), and weaning age (WA) in Awassi lambs. Materials and Methods: A total of 5131 Awassi lambs from two Jordanian sheep breeding stations were used. A multitrait animal model and restricted maximum likelihood methods were used to estimate the covariances between the studied traits...
February 2018: Veterinary World
https://www.readbyqxmd.com/read/29656341/environmental-factors-that-influence-milk-production-of-pantaneiro-ewes-and-the-weight-gain-of-their-lambs-during-the-pre-weaning-period
#7
M L Longo, F M Vargas Junior, K Cansian, M R Souza, P C Burim, A L A Silva, C M Costa, L O Seno
The main objective of this research was to conduct an exploratory study of the lactation curve in order to characterize the productive potential of Pantaneiro ewes and lambs. Fifty ewes were bred using four rams in two different mating seasons. The ewes were kept with their lambs on pasture of Brachiaria brizantha. Ewe body score, ewe weight, and lamb weight were evaluated. Milk sampling was performed every week. In the morning for milk collections, the ewes were treated with 1 UI of oxytocin (intramuscular) for complete milking...
April 14, 2018: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/29652661/combined-brain-and-heart-magnetic-resonance-imaging-in-systemic-vasculitides-fiction-or-real-need
#8
REVIEW
Sophie I Mavrogeni, George Kitas, Hildo J Lamb, Klearchos Psychoyios, Theodoros Dimitroulas, Loukia Koutsogeorgopoulou, Kyriaki Boki, Vasiliki Vartela, Genovefa Kolovou, George Markousis-Mavrogenis, Cees G Kallenberg, Loic Guillevin, Dimitrios Vassilopoulos
Systemic vasculitides (SVs) is a group of diseases characterised by inflammation/necrosis of the blood vessel wall in various organs. Simultaneous brain and heart involvement is a cause of increased morbidity/mortality in SV. We aimed to present evidence of concurrent brain/heart involvement in SV and the role of a combined brain/heart magnetic resonance imaging (MRI) in their risk stratification. Cerebral vasculitis (CV) can be presented as focal deficits, seizures, headache, neuropsychiatric manifestations or cognitive dysfunction and cardiovascular disease (CVD) as myocardial/vascular inflammation, perfusion/function defects and fibrosis...
April 10, 2018: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29652402/broadening-the-optical-bandwidth-of-quantum-cascade-lasers-using-rf-noise-current-perturbations
#9
Tomás H P Pinto, James M R Kirkbride, Grant A D Ritchie
We report on the broadening of the optical bandwidth of a distributed feedback quantum cascade laser (QCL) caused by the application of radio frequency (RF) noise to the injection current. The broadening is quantified both via Lamb-dip spectroscopy and the frequency noise power spectral density (PSD). The linewidth of the unperturbed QCL (emitting at ∼5.3  μm) determined by Lamb-dip spectroscopy is 680±170  kHz, and is in reasonable agreement with the linewidth of 460±40  kHz estimated by integrating the PSD measured under the same laser operating conditions...
April 15, 2018: Optics Letters
https://www.readbyqxmd.com/read/29652076/systematic-reanalysis-of-genomic-data-improves-quality-of-variant-interpretation
#10
S M Hiatt, M D Amaral, K M Bowling, C R Finnila, M L Thompson, D E Gray, J M J Lawlor, J Nicholas Cochran, E Martina Bebin, K B Brothers, K M East, W V Kelley, N E Lamb, S E Levy, E J Lose, M B Neu, C A Rich, S Simmons, R M Myers, G S Barsh, G M Cooper
As genomic sequencing expands, so does our knowledge of the link between genetic variation and disease. Deeper catalogs of variant frequencies improve identification of benign variants, while sequencing affected individuals reveals disease-associated variation. Accumulation of human genetic data thus makes reanalysis a means to maximize benefits of clinical sequencing. We implemented pipelines to systematically reassess sequencing data from 494 individuals with developmental disability. Reanalysis yielded pathogenic or likely pathogenic (P/LP) variants in six individuals who initially had no P/LP variants, a 16% increase to P/LP yield...
April 13, 2018: Clinical Genetics
https://www.readbyqxmd.com/read/29648600/comparison-of-two-alternate-pgf2%C3%AE-products-in-two-estrus-synchronization-protocols-in-beef-heifers
#11
Nicola Oosthuizen, Alicia C Lansford, Luara B Canal, Pedro L P Fontes, Carla D Sanford, Carl R Dahlen, Nicolas DiLorenzo, Rick N Funston, G Cliff Lamb
Two experiments were conducted to evaluate the effects of a high concentrate, s.c. PGF2α compared with a conventionally concentrated, i.m. PGF2α in estrus synchronization protocols for heifers. In Exp. 1, 869 Angus-based beef heifers were enrolled at 8 locations. All heifers were exposed to the 7-d CO-Synch + controlled internal drug release (CIDR) estrus synchronization protocol. On day 7 of the protocol heifers received 100 µg of GnRH i.m., and a CIDR insert for 7 d. On day 0, at CIDR removal, estrous detection patches were applied to heifers and, within location, heifers randomly received 1 of 2 PGF2α treatments: 5 mL of Lutalyse i...
April 10, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29648587/characterization-of-the-ruminal-fermentation-and-microbiome-in-lambs-supplemented-with-hydrolysable-and-condensed-tannins
#12
Saheed A Salami, Bernardo Valenti, Marco Bella, Michael N O ' Grady, Giuseppe Luciano, Joseph P Kerry, Eleanor Jones, Alessandro Priolo, Charles J Newbold
This study characterised the response of ruminal fermentation and the rumen microbiome in lambs fed commercial vegetal sources of hydrolysable tannins (HT) and condensed tannins (CT). Forty-four lambs (19.56 ± 2.06 kg) were randomly assigned to either a concentrate diet (CON, n = 8) or CON supplemented with 4% of two HT [chestnut (Castanea sativa, HT-c) and tara (Caesalpinia spinosa, HT-t)] and CT [mimosa (Acacia negra, CT-m) and gambier (Uncaria gambir, CT-g)] extracts (all, n = 9) for 75 days pre-slaughter...
April 10, 2018: FEMS Microbiology Ecology
https://www.readbyqxmd.com/read/29644603/assessment-of-intake-of-copper-and-lead-by-sheep-grazing-on-a-shooting-range-for-small-arms-a-case-study
#13
Ida Vaa Johnsen, Espen Mariussen, Øyvind Voie
The Norwegian Armed Forces' shooting ranges contain contamination by metals such as lead (Pb) and copper (Cu) and are often used as grazing pastures for livestock. To determine whether the sheep were at risk from grazing at a shooting range in Nord-Trøndelag (the Leksdalen shooting field), a study was conducted wherein the aim was to determine the amount of soil the sheep were eating, the accumulation of Cu and Pb in the livers of lambs grazing on the shooting ranges, and the accumulation of Pb and Cu in the grass...
April 11, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29644180/balancing-the-benefits-and-harms-of-radiotherapy-post-radical-prostatectomy
#14
EDITORIAL
Benjamin W Lamb, Omar Alghazo, Declan G Murphy
No abstract text is available yet for this article.
March 2018: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29642681/the-effect-of-nutrition-and-body-condition-of-triplet-bearing-ewes-during-late-pregnancy-on-the-behaviour-of-ewes-and-lambs
#15
Gabriella V Gronqvist, Rene A Corner-Thomas, Paul R Kenyon, Kevin J Stafford, Stephen T Morris, Rebecca Edith Hickson
Objective: Triplet-born lambs are less likely to survive to weaning than twin-born or single-born lambs. Appropriate ewe-lamb bonding behaviours and lamb vigour behaviours are necessary for survival of lambs. The aim of this experiment was to determine whether maternal nutrition during late pregnancy influenced behaviour of the ewe and her lambs soon after birth, and to determine whether mid-pregnancy body condition score (BCS) influenced any behavioural response. Methods: The experiments included ewes that were in BCS 2...
April 12, 2018: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/29642671/effects-of-different-amylose-to-amylopectin-ratios-on-rumen-fermentation-and-development-in-fattening-lambs
#16
Fangfang Zhao, Aizhong Zhang, Wen Ren, Ning Jiang, Wen Liu, Faming Wang
Objective: The objective of this experiment was to examine the effects of different amylose/amylopectin ratios on rumen fermentation and development of fattening lambs. Methods: Forty-eight 7-day-old male Small-tailed Han sheep × Northeast fine wool sheep were randomly assigned to four treatments of dietary amylose/amylopectin ratios (0.12, 0.23, 0.24 and 0.48 in tapioca starch, corn starch, wheat starch and pea starch diets, respectively). Three lambs from each treatment were slaughtered at 21, 35, 56 and 77 days of age to determine the rumen fermentation and development...
April 12, 2018: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/29642666/expression-of-selenium-independent-glutathione-peroxidase-5-gpx5-in-the-epididymis-of-small-tail-han-sheep
#17
Ruilan Li, Xiaomei Fan, Tong Zhang, Huizi Song, Xiaona Bian, Rile Nai, Jinquan Li, Jiaxin Zhang
Objective: Selenium-independent glutathione peroxidase (GPx5) is specifically expressed in the mammalian epididymis and plays an important role in protecting sperm from reactive oxygen species (ROS) and lipid peroxidation damage. This study investigates GPx5 expression in the epididymis of Small Tail Han sheep. Methods: GPx5 expression was studied in three age groups: lamb (2-3 months), young (8-10 months), and adult (18-24 months). The epididymis of each age group divided into caput , corpus and cauda , respectively...
April 12, 2018: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/29629594/a-qualitative-study-of-patient-experience-of-an-open-fracture-of-the-lower-limb-during-acute-care
#18
E Tutton, J Achten, S E Lamb, K Willett, M L Costa
Aims The aim of this study was to explore the patients' experience of recovery from open fracture of the lower limb in acute care. Patients and Methods A purposeful sample of 20 participants with a mean age of 40 years (20 to 82) (16 males, four females) were interviewed a mean of 12 days (five to 35) after their first surgical intervention took place between July 2012 and July 2013 in two National Health Service (NHS) trusts in England, United Kingdom. The qualitative interviews drew on phenomenology and analysis identified codes, which were drawn together into categories and themes...
April 1, 2018: Bone & Joint Journal
https://www.readbyqxmd.com/read/29628290/the-immune-landscape-of-cancer
#19
Vésteinn Thorsson, David L Gibbs, Scott D Brown, Denise Wolf, Dante S Bortone, Tai-Hsien Ou Yang, Eduard Porta-Pardo, Galen F Gao, Christopher L Plaisier, James A Eddy, Elad Ziv, Aedin C Culhane, Evan O Paull, I K Ashok Sivakumar, Andrew J Gentles, Raunaq Malhotra, Farshad Farshidfar, Antonio Colaprico, Joel S Parker, Lisle E Mose, Nam Sy Vo, Jianfang Liu, Yuexin Liu, Janet Rader, Varsha Dhankani, Sheila M Reynolds, Reanne Bowlby, Andrea Califano, Andrew D Cherniack, Dimitris Anastassiou, Davide Bedognetti, Arvind Rao, Ken Chen, Alexander Krasnitz, Hai Hu, Tathiane M Malta, Houtan Noushmehr, Chandra Sekhar Pedamallu, Susan Bullman, Akinyemi I Ojesina, Andrew Lamb, Wanding Zhou, Hui Shen, Toni K Choueiri, John N Weinstein, Justin Guinney, Joel Saltz, Robert A Holt, Charles E Rabkin, Alexander J Lazar, Jonathan S Serody, Elizabeth G Demicco, Mary L Disis, Benjamin G Vincent, Llya Shmulevich
We performed an extensive immunogenomic analysis of more than 10,000 tumors comprising 33 diverse cancer types by utilizing data compiled by TCGA. Across cancer types, we identified six immune subtypes-wound healing, IFN-γ dominant, inflammatory, lymphocyte depleted, immunologically quiet, and TGF-β dominant-characterized by differences in macrophage or lymphocyte signatures, Th1:Th2 cell ratio, extent of intratumoral heterogeneity, aneuploidy, extent of neoantigen load, overall cell proliferation, expression of immunomodulatory genes, and prognosis...
April 4, 2018: Immunity
https://www.readbyqxmd.com/read/29626239/high-spatial-resolution-free-breathing-3d-late-gadolinium-enhancement-cardiac-magnetic-resonance-imaging-in-ischaemic-and-non-ischaemic-cardiomyopathy-quantitative-assessment-of-scar-mass-and-image-quality
#20
Maurice B Bizino, Qian Tao, Jacob Amersfoort, Hans-Marc J Siebelink, Pieter J van den Bogaard, Rob J van der Geest, Hildo J Lamb
PURPOSE: To compare breath-hold (BH) with navigated free-breathing (FB) 3D late gadolinium enhancement cardiac MRI (LGE-CMR) MATERIALS AND METHODS: Fifty-one patients were retrospectively included (34 ischaemic cardiomyopathy, 14 non-ischaemic cardiomyopathy, three discarded). BH and FB 3D phase sensitive inversion recovery sequences were performed at 3T. FB datasets were reformatted into normal resolution (FB-NR, 1.46x1.46x10mm) and high resolution (FB-HR, isotropic 0.91-mm voxels). Scar mass, scar edge sharpness (SES), SNR and CNR were compared using paired-samples t-test, Pearson correlation and Bland-Altman analysis...
April 6, 2018: European Radiology
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