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Abdominal aortic aneurysms

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https://www.readbyqxmd.com/read/28549310/segmentation-of-lumen-and-outer-wall-of-abdominal-aortic-aneurysms-from-3d-black-blood-mri-with-a-registration-based-geodesic-active-contour-model
#1
Yan Wang, Florent Seguro, Evan Kao, Yue Zhang, Farshid Faraji, Chengcheng Zhu, Henrik Haraldsson, Michael Hope, David Saloner, Jing Liu
Segmentation of the geometric morphology of abdominal aortic aneurysm is important for interventional planning. However, the segmentation of both the lumen and the outer wall of aneurysm in magnetic resonance (MR) image remains challenging. This study proposes a registration based segmentation methodology for efficiently segmenting MR images of abdominal aortic aneurysms. The proposed methodology first registers the contrast enhanced MR angiography (CE-MRA) and black-blood MR images, and then uses the Hough transform and geometric active contours to extract the vessel lumen by delineating the inner vessel wall directly from the CE-MRA...
May 19, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/28548204/endovascular-treatment-for-ruptured-abdominal-aortic-aneurysm
#2
REVIEW
Stephen Badger, Rachel Forster, Paul H Blair, Peter Ellis, Frank Kee, Denis W Harkin
BACKGROUND: An abdominal aortic aneurysm (AAA) (pathological enlargement of the aorta) is a condition that can occur as a person ages. It is most commonly seen in men older than 65 years of age. Progressive aneurysm enlargement can lead to rupture and massive internal bleeding, which is fatal unless timely repair can be achieved. Despite improvements in perioperative care, mortality remains high (approximately 50%) after conventional open surgical repair. Endovascular aneurysm repair (EVAR), a minimally invasive technique, has been shown to reduce early morbidity and mortality as compared to conventional open surgery for planned AAA repair...
May 26, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28546046/on-the-use-of-geometric-modeling-to-predict-aortic-aneurysm-rupture
#3
Sruthi L Muluk, Pallavi D Muluk, Judy Shum, Ender A Finol
BACKGROUND: Currently, the risk of abdominal aortic aneurysm (AAA) rupture is determined using the maximal diameter (Dmax) of the aorta. We sought in this study to identify a set of CT-based geometric parameters that would better predict the risk of rupture than Dmax. METHODS: We obtained CT Scans from 180 patients (90 ruptured AAA, 90 elective AAA repair) and then used automated software to calculate 1-dimensional, 2-dimensional, and 3-dimensional geometric parameters for each AAA...
May 22, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28546044/endovascular-repair-of-thoraco-abdominal-and-arch-aneurysms-in-patients-with-connective-tissue-disease-using-branched-and-fenestrated-devices
#4
Rachel E Clough, Teresa Martin-Gonzalez, Katrien Van Calster, Adrien Hertault, Rafaëlle Spear, Richard Azzaoui, Jonathan Sobocinski, Stéphan Haulon
INTRODUCTION: Prophylactic open surgery is the standard practice in patients with connective tissue and thoraco-abdominal (TAAA) and aortic arch disease. Branched and fenestrated devices offer a less invasive alternative but there are concerns regarding the durability of the repair and the effect of the stent graft on the fragile aortic wall. The aim of this study was to evaluate mid-term outcomes of fenestrated and/or branched endografting in patients with connective tissue disease. METHODS: All patients with connective tissue disease that underwent TAAA or arch aneurysm repair using a fenestrated and/or branched endograft in a single high volume centre between 2004 and 2015 were included...
May 22, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28546041/10-years-single-centre-results-of-abdominal-aortic-aneurysm-treatment-endovascular-vs-open-repair
#5
Payman Majd, Wael Ahmad, Ingrid Becker, Jan Sigge Brunkwall
OBJECTIVES: The purpose of the present study was to compare the long-term survival in matched cohorts of patients with infrarenal abdominal aortic aneurysm (AAA) undergoing an elective open repair (OR) or an endovascular aneurysm repair (EVAR). MATERIALS AND METHODS: Patients with a primary elective repair of an infrarenal aortic aneurysm between 1998 and 2006 were identified in a retrospective review of our single centre database. EVAR and OR patients were matched with respect to age, gender, renal disease, tobacco use, hypertension, chronic obstructive pulmonary disease and coronary artery disease...
May 22, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28545777/inhibitory-effects-of-doxycycline-on-the-onset-and-progression-of-abdominal-aortic-aneurysm-and-its-related-mechanisms
#6
Maomao Yu, Cong Chen, Yini Cao, Rong Qi
The objective of this study was to investigate whether doxycycline (DOX) given at different doses and via different administration routes had protective or therapeutic effects on abdominal aortic aneurysm (AAA) induced by elastase in mice. Moreover, the anti-AAA mechanism of DOX was studied in TNF-α-stimulated vascular smooth muscle cell (VSMC) in vitro. For in vivo study, either daily administration of 30mg/kg of DOX by gavage or intraperitoneal injection of 15mg/kg DOX every other day for 14 days significantly prevented the development of AAA at its early stage...
May 22, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28545328/diabetes-mellitus-increases-the-risk-of-ruptured-abdominal-aortic-aneurysms
#7
Waldemar Wierzba, Andrzej Sliwczynski, Jaroslaw Pinkas, Arkadiusz Jawien, Waldemar Karnafel
The publication is a polemical response to reports that present data that diabetes reduces the risk of rupture of abdominal aortic aneurysm (AAA). The study analyzed all cases of developing AAA in patients with and without diabetes in 2012 in Poland. Data for the analysis were obtained with a unique and complete resources of the National Health Fund (NFZ) and population data from the Central Statistical Office (GUS). In Poland during 2012 2,227,453 patients with diabetes were treated, 975,364 males and 1,252,089 females...
May 1, 2017: Diabetes & Vascular Disease Research
https://www.readbyqxmd.com/read/28540077/role-of-molecular-imaging-with-positron-emission-tomographic-in-aortic-aneurysms
#8
REVIEW
Parmanand Singh, Zaid Almarzooq, Brian Salata, Richard B Devereux
Aortic aneurysms (AA) are often asymptomatic before the occurrence of acute, potentially fatal complications including dissection and/or rupture. Beyond aortic size, the ability to assess aortic wall characteristics and processes contributing to aneurysm development may allow improved selection of patients who may benefit from prophylactic surgical intervention. Current risk stratification for aneurysms relies upon routine noninvasive imaging of aortic size without assessing the underlying pathophysiologic processes, including features such as inflammation, which may be associated with aneurysm development and progression...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28539057/abdominal-aortic-aneurysm-screening-do-we-need-to-shift-toward-a-targeted-strategy
#9
Konstantinos Spanos, Nicos Labropoulos, Athanasios Giannoukas
No abstract text is available yet for this article.
January 1, 2017: Angiology
https://www.readbyqxmd.com/read/28538996/the-relationship-between-surface-curvature-and-abdominal-aortic-aneurysm-wall-stress
#10
Sergio Ruiz de Galarreta, Aitor Cazon, Raúl Antón, Ender A Finol
The maximum diameter criterion is the most important factor when predicting risk of rupture of abdominal aortic aneurysms (AAA). An elevated wall stress has also been linked to a high risk of aneurysm rupture, yet is an uncommon clinical practice to compute AAA wall stress. The purpose of this study is to assess whether other characteristics of the AAA geometry are statistically correlated with wall stress. Using in-house segmentation and meshing algorithms, thirty patient-specific AAA models were generated for finite element analysis...
May 24, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28535909/dynamic-simulation-and-doppler-ultrasonography-validation-of-blood-flow-behavior-in-abdominal-aortic-aneurysm
#11
Cristian C Botar, Árpád Á Tóth, Olivera R Klisurić, Dijana D Nićiforović, Viktorija A Vučaj Ćirilović, Viktor E Till
Criteria for rupture prediction of Abdominal Aortic Aneurysm (AAA) are based only on the diameter of AAA. This method does not consider complex hemodynamic forces exerted on AAA wall. The methodology used in our study combines Computer-Aided Design (CAD) with Computational Fluid Dynamics (CFD). Three-dimensional vascular structures reconstructions were based on Computed Tomography (CT) images and CAD. CFD theory was used for mathematical modeling and simulations. In this way, dynamic behavior of blood flow in bounded three-dimensional space was described...
May 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28535733/access-from-above-bailout-solution-for-intraoperative-distal-migration-of-abdominal-aortic-stent-graft
#12
Dimitrij Kuhelj, Jernej Avsenik, Dašmir Nuredini
The majority of the ruptured abdominal aortic aneurysms today is treated endovascularly. In cases with short aneurysm neck, chimney technique can be used to extend landing zone in emergency setting. Additionally, the repositioning ability of C3 delivery system (Gore & Associates) allows better positioning in cases with challenging anatomy. In our experience, proximal reposition of partially deployed device can be problematic in some patients. We present a case of endovascular repair of ruptured abdominal aortic aneurysm using chimney technique where proximal reposition was achieved by snaring the aortic device via axillary access...
January 1, 2017: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28535732/duplex-ultrasound-surveillance-after-uncomplicated-endovascular-abdominal-aortic-aneurysm-repair
#13
Jacob S Schaeffer, Irina Shakhnovich, Kyle N Sieck, Kara J Kallies, Clark A Davis, Thomas H Cogbill
OBJECTIVES: Health-care costs and risks of radiation and intravenous contrast exposure challenge computed tomography angiography (CTA) as the standard surveillance method after endovascular abdominal aortic aneurysm repair (EVAR). We reviewed our experience using Duplex ultrasound scan (DUS) as an initial and subsequent surveillance technique after uncomplicated EVAR. METHODS: The medical records of patients who underwent EVAR from 2004 to 2014 with at least 1 postoperative imaging study were retrospectively reviewed...
January 1, 2017: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28528280/aortic-involvement-in-relapsing-polychondritis
#14
Maëlle Le Besnerais, Laurent Arnaud, Jonathan Boutémy, Boris Bienvenu, Hervé Lévesque, Zahir Amoura, Isabelle Marie
OBJECTIVE: To assess prevalence of aortic involvement in relapsing polychondritis (RP) patients; to evaluate clinical features and long-term outcome of RP patients exhibiting aortitis, aortic ectasia and/or aneurysm. METHODS: 172 RP patients underwent aortic computed tomography (CT)-scan; they were seen in 3 medical centers. RESULTS: 11 patients (6.4%) had aortic involvement, occurring within a median time of 2 years after RP diagnosis. CT-scan showed isolated aortitis (n=2); the 9 other patients exhibited: aortitis and aortic aneurysm (n=2) or ectasia (n=1), isolated aortic aneurysm (n=4) or ectasia (n=2); aortic localizations were as follows: thoracic (n=6), abdominal (n=2), thoracic and abdominal (n=4) aorta...
May 17, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28528045/endovascular-fenestration-for-distal-aortic-sealing-after-frozen-elephant-trunk-with-thoraflex
#15
Randolph H L Wong, Peter S Y Yu, Micky W T Kwok, Simon C Y Chow, Jacky Y K Ho, Malcolm J Underwood, Simon C H Yu
We describe a case of total arch replacement with frozen elephant trunk for chronic type B aortic dissecting aneurysm, which resulted in inadvertent landing of the frozen elephant trunk into the false lumen. A radiofrequency puncture system-assisted controlled endovascular fenestration of the dissection flap was performed at the upper abdominal aorta and subsequent thoracic endovascular stenting, successfully redirecting the blood flow from the false to the true lumen. Our case illustrated a possible way to seal distal reentry in chronic type B aortic dissection...
June 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28527818/predictors-associated-with-increased-prevalence-of-abdominal-aortic-aneurysm-in-chinese-patients-with-atherosclerotic-risk-factors
#16
W Li, S Luo, J Luo, Y Liu, B Ning, W Huang, L Xue, J Chen
OBJECTIVE/BACKGROUND: Epidemiological screening studies have demonstrated that the prevalence of abdominal aortic aneurysm (AAA) of Asian origin appears to be low and so increases uncertainty about the cost effectiveness of screening for AAAs in Chinese people. Some studies have demonstrated a higher prevalence of AAA in patients with atherosclerotic risk factors. The purpose of the study was to determine the prevalence of AAA and to explore the high risk group of AAA in Chinese patients with atherosclerotic risk factors...
May 17, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28527730/experiences-of-the-screening-process-and-the-diagnosis-abdominal-aortic-aneurysm-among-65-year-old-men-from-invitation-to-a-1-year-surveillance
#17
Monica Pettersson, Anders Hansson, John Brodersen, Christine Kumlien
The prevalence of abdominal aortic aneurysm (AAA) is reported to be 2.2%-8% among men >65 years. During recent years, screening programs have been developed to detect AAA, prevent ruptures, and thereby saving lives. Therefore, most men with the diagnosis are monitored conservatively with regular reviews. The objective of the study was to describe how men diagnosed with abdominal aortic aneurysm <55 mm discovered by screening experience the process and diagnosis from invitation to 1 year after screening...
June 2017: Journal of Vascular Nursing: Official Publication of the Society for Peripheral Vascular Nursing
https://www.readbyqxmd.com/read/28527353/mechanical-behavior-of-the-abdominal-aortic-aneurysm-assessed-by-biaxial-tests-in-the-rat-xenograft-model
#18
Louise Marais, Mustapha Zidi
This paper addresses the mechanical biaxial behavior of degraded arteries obtained by the rat xenograft model. For that, a pressure myograph was used to perform extension-inflation tests on abdominal aortic aneurysms (AAAs). Furthermore, residual stresses in the aneurismal wall were assessed by opening angle tests. Thus, the changes in mechanical behavior between native murine aortas, decellularized guinea pig aortas (the grafts) and degraded aortas (AAAs) were investigated. It was shown that decellularized and degraded aortas exhibited a different mechanical behavior than native murine aortas...
May 12, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28527199/the-value-of-contrast-enhanced-ultrasound-ceus-using-a-high-end-ultrasound-system-in-the-characterization-of-endoleaks-after-endovascular-aortic-repair-evar
#19
J Rübenthaler, M Reiser, V Cantisani, D Rjosk-Dendorfer, D A Clevert
PURPOSE: To evaluate the value of contrast-enhanced ultrasound (CEUS) using a high-end ultrasound system in the characterization of endoleaks after endovascular aortic repair (EVAR). MATERIAL AND METHODS: In this mono-center study, 41 patients were retrospectively analyzed after being examined using a modern high-end ultrasound system (RS80A with Prestige, Samsung Medison Co., Ltd., Seoul, Korea). The maximum diameters of the aneurysms were measured in two planes (right-left and ventral-dorsal)...
May 18, 2017: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/28526396/the-impact-of-initial-misdiagnosis-of-ruptured-abdominal-aortic-aneurysms-on-lead-times-complication-rate-and-survival
#20
K Smidfelt, C Drott, K Törngren, J Nordanstig, J Herlitz, M Langenskiöld
OBJECTIVE/BACKGROUND: To investigate the frequency of initial misdiagnosis and the clinical consequences of an initial misdiagnosis of ruptured abdominal aortic aneurysms (rAAA). METHODS: This was a retrospective cohort study. Data from the Swedish National Registry for Vascular Surgery (Swedvasc) and medical charts were extracted for patients treated for rAAA in the West of Sweden in the period 2008-14. Initially misdiagnosed patients were compared with correctly diagnosed patients...
May 16, 2017: European Journal of Vascular and Endovascular Surgery
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