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https://www.readbyqxmd.com/read/29770267/role-of-noninvasive-imaging-of-cerebral-arterial-system-in-ischemic-stroke-comparison-of-transcranial-color-coded-doppler-sonography-with-magnetic-resonance-angiography
#1
Betty Simon, Sunithi Elizabeth Mani, Shyamkumar Nidugala Keshava, Mathew Alexander, Sanjith Aaron
Aim: To determine the accuracy of transcranial color-coded Doppler sonography (TCCS) in the evaluation of cerebral arterial system in patients with ischemic stroke attending a tertiary care hospital in South India. Objectives: (1) To describe the topographical distribution of atherosclerotic lesions in the cerebral circulation in patients presenting with ischemic stroke from the Indian subcontinent and (2) to determine the accuracy of TCCS for detection and quantification of intracranial stenoses in various segments of the intracerebral arterial system in comparison with magnetic resonance angiography (MRA)...
2018: Journal of Clinical Imaging Science
https://www.readbyqxmd.com/read/29767351/evaluating-the-methods-used-for-measuring-cerebral-blood-flow-at-rest-and-during-exercise-in-humans
#2
REVIEW
Michael M Tymko, Philip N Ainslie, Kurt J Smith
The first accounts of measuring cerebral blood flow (CBF) in humans were made by Angelo Mosso in ~1880, who recorded brain pulsations in patients with skull defects. In 1890, Charles Roy and Charles Sherrington determined in animals that brain pulsations-assessed via a similar method used by Mosso-were altered during a variety of stimuli including sensory nerve stimulation, asphyxia, and pharmacological interventions. Between 1880 and 1944, measurements for CBF were typically relied on skull abnormalities in humans...
May 16, 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29766604/sodium-nitroglycerin-induces-middle-cerebral-artery-vasodilation-in-young-healthy-adults
#3
Jenna M Schulz, Baraa K Al-Khazraji, J Kevin Shoemaker
Recent evidence indicates that basal cerebral conduit vessels dilate with hypercapnia, with a nitric oxide (NO) mechanism explaining one way in which parenchymal cerebral arterioles dilate. However, whether NO affects basal cerebral artery dilation remains unknown. This study quantified the effect of an exogenous NO donor [sodium nitroglycerin (NTG); 0.4 mg sublingual spray] on the right middle cerebral artery (rMCA) cross-sectional area (CSA), blood velocity and overall blood flow. Measures of vessel CSA (7 Tesla magnetic resonance imaging) and MCA blood velocity (transcranial Doppler ultrasound) were made at baseline (BL), and following exogenous NTG or placebo (PLO) administration in young, healthy individuals (n = 10, 2 males, age range 20-23 years)...
May 15, 2018: Experimental Physiology
https://www.readbyqxmd.com/read/29755714/identification-of-cerebral-artery-stenosis-using-bilateral-photoplethysmography
#4
Hyun Goo Kang, Seogki Lee, Han Uk Ryu, Youngsuk Shin
Cerebral artery stenosis is currently diagnosed by transcranial Doppler (TCD), computed tomographic angiography (CTA), or magnetic resonance angiography (MRA). CTA exposes a patient to radiation, while CTA and MRA are invasive and side effects were related to contrast medium use. This study aims to provide a technique that can simply discriminate between people with normal blood vessels and those with cerebral artery stenosis using photoplethysmography (PPG), which is noninvasive and inexpensive. Moreover, the measurement takes only 120 seconds and is conducted on the fingers...
2018: Journal of Healthcare Engineering
https://www.readbyqxmd.com/read/29750475/effects-of-losartan-and-allopurinol-on-cardiorespiratory-regulation-in-obstructive-sleep-apnoea
#5
Barbara J Morgan, Mihaela Teodorescu, David F Pegelow, Emily R Jackson, Devin L Schneider, David T Plante, James P Gapinski, Scott J Hetzel, John M Dopp
Chemoreflex sensitization produced by chronic intermittent hypoxia (CIH) in rats is attenuated by angiotensin II type 1 receptor (AT1 R) blockade. AT1 R blockade and xanthine oxidase inhibition both ameliorate CIH-induced endothelial dysfunction. We hypothesized treatment with losartan and allopurinol would reduce chemoreflex sensitivity and improve hypoxic vasodilation in patients with obstructive sleep apnoea (OSA). Eighty-six hypertensive patients with apnoea-hypopnoea index ≥25 events/hr and no other cardiovascular, pulmonary, renal, or metabolic disease were randomly assigned to receive allopurinol, losartan, or placebo for 6 weeks...
May 11, 2018: Experimental Physiology
https://www.readbyqxmd.com/read/29746600/impact-of-positive-end-expiratory-pressure-on-cerebral-hemodynamic-in-paediatric-patients-with-post-traumatic-brain-swelling-treated-by-surgical-decompression
#6
Silvia De Rosa, Gianluca Villa, Paola Franchi, Aldo Mancino, Federica Tosi, Marina Alessandra Martin, Simona Bazzano, Giorgio Conti, Silvia Maria Pulitanò
INTRODUCTION: The objective of our present study is to evaluate the impact of different PEEP levels on cerebral hemodynamic, gas exchanges and respiratory system mechanics in paediatric patients with post-traumatic brain swelling treated with decompressive craniectomy (DC). MATERIALS AND METHODS: A prospective physiologic study was carried out on 14 paediatric patients presenting with severe traumatic brain swelling treated with DC. Transcranial Doppler ultrasonography was performed on the middle cerebral artery bilaterally after DC...
2018: PloS One
https://www.readbyqxmd.com/read/29744017/spontaneous-recanalization-after-carotid-artery-dissection-the-case-for-an-ultrasound-only-monitoring-strategy
#7
Sarah Lumsden, Gabor Rosta, Jean Bismuth, Alan B Lumsden, Zsolt Garami
Dissection of the internal carotid artery (ICA) accounts for 5% to 25% of ischemic strokes in young adults. We report a case of spontaneous recanalization of a traumatic ICA dissection in which carotid duplex (CDU) and transcranial color-coded duplex ultrasound (TCCD) were used. A 47-year-old male presented with intermittent episodes of headache, blurry vision, anisocoria, and loss of taste sensation following a whiplash injury while body surfing. Magnetic resonance angiogram (MRA) of the neck revealed absent flow in the cavernous ICA and a clot at the skull base...
October 2017: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/29732592/transcranial-doppler-ultrasound-in-peninsular-arab-patients-with-sickle-cell-disease
#8
Adekunle Adekile, Meaad Hassan, Akram Asbeutah, Mohamed Al-Hinai, Omar Trad, Nayef Farhan
OBJECTIVES: Transcranial Doppler ultrasound is used to identify patients with sickle cell disease (SCD) at risk for stroke. We performed transcranial Doppler studies in patients from 4 countries in the Arabian Peninsula (Kuwait, Oman, Iraq, and United Arab Emirates) to document the prevalence of abnormal transcranial Doppler findings. METHODS: The patients were recruited from outpatient clinics and studied in a steady state. Transcranial Doppler examinations were performed with standard equipment by experienced operators...
May 6, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29727515/microv-technology-to-improve-transcranial-color-coded-doppler-examinations
#9
Giovanni Malferrari, Giuseppe Pulito, Attilia Maria Pizzini, Nicola Carraro, Giorgio Meneghetti, Enzo Sanzaro, Patrizio Prati, Antonio Siniscalchi, Daniela Monaco
The purpose of this review is to provide an update on technology related to Transcranial Color Coded Doppler Examinations. Microvascularization (MicroV) is an emerging Power Doppler technology which can allow visualization of low and weak blood flows even at high depths, thus providing a suitable technique for transcranial ultrasound analysis. With MicroV, reconstruction of the vessel shape can be improved, without any overestimation. Furthermore, by analyzing the Doppler signal, MicroV allows a global image of the Circle of Willis...
May 4, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29725955/analysis-of-cerebral-blood-flow-and-intracranial-hypertension-in-critical-patients-with-non-hepatic-hyperammonemia
#10
Alexandre Sanches Larangeira, Marcos Toshiyuki Tanita, Marcos Antonio Dias, Olavo Franco Ferreira Filho, Vinicius Daher Alvares Delfino, Lucienne Tibery Queiroz Cardoso, Cintia Magalhães Carvalho Grion
Hyperammonemia in adults is generally associated with cerebral edema, decreased cerebral metabolism, and increased cerebral blood flow. The aim of this study was to evaluate the association between non-hepatic hyperammonemia and intracranial hypertension assessed by Doppler flowmetry and measurement of the optic nerve sheath. A prospective cohort study in critically ill patients hospitalized in intensive care units of a University Hospital between March 2015 and February 2016. Clinical data and severity scores were collected and the Glasgow coma scale was recorded...
May 3, 2018: Metabolic Brain Disease
https://www.readbyqxmd.com/read/29725389/imaging-characteristics-and-pathogenesis-of-intracranial-artery-stenosis-in-patients-with-acute-cerebral-infarction
#11
Wenyuan Xu, Ning Xie, Cheng Zhang, Qin Huang
The current study aimed to investigate the imaging characteristics and pathogenesis of intracranial artery stenosis in patients with acute cerebral infarction. In total, 84 patients diagnosed with acute cerebral infarction were recruited. Magnetic resonance angiography was performed to detect the existence of intracranial artery stenosis or occlusion. In addition, magnetic resonance imaging and diffusion weighted imaging were employed to analyze the infarction types and characteristics. In the majority of patients, the infarction resulted from internal carotid stenosis (77 cases; 91...
May 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29725189/definity-contrast-artifact-in-transcranial-doppler-emboli-monitoring
#12
Ramnath Santosh Ramanathan
No abstract text is available yet for this article.
April 2018: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/29712500/effects-of-fentanyl-for-pain-control-and-neuroprotection-in-very-preterm-newborns-on-mechanical-ventilation
#13
Jie Qiu, Li Zhao, Yang Yang, Jing-Han Zhang, Yun Feng, Rui Cheng
OBJECTIVE: This study aimed to evaluate the cerebral protection effect of fentanyl infusion in very preterm infants in the first 72 h of mechanical ventilation. METHODS: In this double-blind, randomized, controlled trial, mechanically ventilated newborns (< 32 weeks' gestational age) were randomized to fentanyl (continuous infusion of fentanyl) or placebo (continuous infusion of glucose, controls) in the first 72 h of the mechanical ventilation period. The premature infant pain profile (PIPP), cerebral blood flow velocity, neuron-specific enolase (NSE) concentrations in plasma samples, and cerebral function monitoring (CFM) recordings were evaluated...
April 30, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29703414/lactotripeptide-ingestion-increases-cerebral-blood-flow-velocity-in-middle-aged-and-older-adults
#14
Nobuhiko Akazawa, Ai Hamasaki, Koichiro Tanahashi, Keisei Kosaki, Toru Yoshikawa, Kanae Myoenzono, Seiji Maeda
The age-related decrease in cerebral blood flow velocity increases the risk of cerebrovascular disease. Milk protein-derived bioactive peptides, e.g., lactotripeptide (LTP), have been shown to inhibit angiotensin converting enzyme activities and increase vasodilator production. We hypothesized that LTP ingestion increases cerebral blood flow velocity in middle-aged and older adults. In a randomized, placebo-controlled, double-blind design, 15 healthy middle-aged and older adults were assigned to either a LTP group or a placebo group...
March 23, 2018: Nutrition Research
https://www.readbyqxmd.com/read/29693475/transcranial-doppler-ultrasonography-cerebral-blood-flow-dynamics-study-of-neurosurgical-patients-in-peri-agonal-period-with-fixed-dilated-or-non-reacting-pupils
#15
Pratyush Shrestha, Safiur Rahman Ansari, Ram Kumar Ghimire, Dinesh Nath Gongal, Upendra Psd Devkota
INTRODUCTION: Fixed dilated and unreactive pupils are a harbinger of imminent death in neurosurgical patients, signifying that the brainstem is not functioning. Transcranial Doppler (TCD) ultrasonography is a noninvasive, bedside method of determining the flow velocities in the basal cerebral arteries, used extensively in various neurosurgical conditions. AIMS AND OBJECTIVES: To study the cerebral blood flow dynamics of neurosurgical patients in peri-agonal period with fixed dilated or non reacting pupils using TCD...
April 25, 2018: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/29687959/aerobic-exercise-training-enhances-cerebrovascular-pulsatility-response-to-acute-aerobic-exercise-in-older-adults
#16
Nobuhiko Akazawa, Koichiro Tanahashi, Keisei Kosaki, Song-Gyu Ra, Tomoko Matsubara, Youngju Choi, Asako Zempo-Miyaki, Seiji Maeda
The brain's low resistance ensures a robust blood flow throughout systole and diastole and is susceptible to flow pulsatility. Increased cerebral pulsatility contributes to the progression of cerebrovascular disease. Although aerobic exercise affects vascular function, little is known about the effect of exercise on the cerebral pulsatility index in older adults. The aim of this study was to investigate the effect of exercise training on the post-exercise cerebral pulsatility response in older adults. Ten healthy older adults participated in a 12-week exercise training intervention...
April 2018: Physiological Reports
https://www.readbyqxmd.com/read/29687859/clinical-diagnosis-of-cerebral-vasospasm-after-subarachnoid-hemorrhage-by-using-transcranial-doppler-sonography
#17
D-D Li, J-Y Chang, C-X Zhou, J-B Cui
OBJECTIVE: To investigate the diagnosis of cerebral vasospasm (CVS) after subarachnoid hemorrhage (SAH) by transcranial Doppler (TCD) sonography. PATIENTS AND METHODS: 90 patients with SAH admitted to the Department of Neurosurgery of Weifang People's Hospital from January 2016 to December 2016 were selected. TCD and digital subtraction angiography (DSA) were used to diagnose the prevalence of CVS in patients. The severity of disease was evaluated (improved-Fisher grading)...
April 2018: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29685515/cerebral-embolization-during-endovascular-infrarenal-juxtarenal-and-suprarenal-aortic-aneurysm-repair-high-risk-maneuvers-and-associated-neurologic-outcomes
#18
Ruth A Benson, David Matthews, Vanessa Loftus, Grainne Nicholson, David Tropman, Ian M Loftus
BACKGROUND: Risk factors for postoperative cognitive decline after noncardiac surgery are multifactorial and poorly understood. Evidence suggests that perioperative microembolic damage to the brain on movement of wires and catheters during endovascular aortic procedures may play an important role. Endovascular aortic aneurysm repair requires invasive manipulation of wires and cannulas within the aorta, but research into cerebral emboli during aortic aneurysm repair and cognitive or neurologic injury is scarce and limited to thoracic aneurysms...
April 20, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29677060/cerebral-small-vessel-but-not-large-vessel-disease-is-associated-with-impaired-cerebral-autoregulation-during-cardiopulmonary-bypass-a-retrospective-cohort-study
#19
Yohei Nomura, Roland Faegle, Daijiro Hori, Abbas Al-Qamari, Alexander J Nemeth, Rebecca Gottesman, Gayane Yenokyan, Charles Brown, Charles W Hogue
BACKGROUND: Impaired cerebral blood flow (CBF) autoregulation during cardiopulmonary bypass (CPB) is associated with stroke and other adverse outcomes. Large and small arterial stenosis is prevalent in patients undergoing cardiac surgery. We hypothesize that large and/or small vessel cerebral arterial disease is associated with impaired cerebral autoregulation during CPB. METHODS: A retrospective cohort analysis of data from 346 patients undergoing cardiac surgery with CPB enrolled in an ongoing prospectively randomized clinical trial of autoregulation monitoring were evaluated...
April 17, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29675634/investigation-of-circle-of-willis-variants-and-hemodynamic-parameters-in-twins-using-transcranial-color-coded-doppler-sonography
#20
Bianka Forgó, Ádám Domonkos Tárnoki, Dávid László Tárnoki, Levente Littvay, Corrado Fagnani, Maria Antonietta Stazi, Giorgio Meneghetti, Emanuela Medda, Filippo Farina, Claudio Baracchini
Morphological and hemodynamic variations of the circle of Willis (CW) may have an important impact on cerebrovascular events. However, the environmental and genetic influence remains unclear. For this reason we studied the variations and hemodynamic parameters of the CW in twins using transcranial color-coded sonography (TCCS). Sixty-four twins, 19 monozygotic (MZ) and 13 dizygotic (DZ) pairs from the Italian Twin Registry (average age 45.0 ± 13.7 years) underwent TCCS and risk factor assessment. We examined CW morphology and recorded peak systolic velocity (PSV), end-diastolic velocity (EDV) and pulsatility index (PI)...
April 19, 2018: International Journal of Cardiovascular Imaging
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