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https://www.readbyqxmd.com/read/28229841/-neuroimaging-and-blood-biomarkers-in-functional-prognosis-after-stroke
#1
REVIEW
João Paulo Branco, Joana Santos Costa, João Sargento-Freitas, Sandra Oliveira, Bruno Mendes, Jorge Laíns, João Pinheiro
INTRODUCTION: Stroke remains one of the leading causes of morbidity and mortality around the world and it is associated with an important long-term functional disability. Some neuroimaging resources and certain peripheral blood or cerebrospinal fluid proteins can give important information about etiology, therapeutic approach, follow-up and functional prognosis in acute ischemic stroke patients. However, among the scientific community, there is currently more interest in the stroke vital prognosis over the functional prognosis...
November 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28229321/cerebral-endothelial-dysfunction-in-reversible-cerebral-vasoconstriction-syndrome-a-case-control-study
#2
Hyun Ah Choi, Mi Ji Lee, Chin-Sang Chung
BACKGROUND: The aim of this study is to investigate cerebral endothelial dysfunction in patients with reversible cerebral vasoconstriction syndrome (RCVS). METHODS: We prospectively recruited patients with RCVS, age-matched controls with episodic migraine, and age-matched healthy controls at Samsung Medical Center from Apr 2015 to Jul 2016. All participants underwent transcranial Doppler evaluation, with a breath-holding maneuver, for the evaluation of bilateral middle cerebral arteries (MCAs), posterior cerebral arteries (PCAs), and the basilar artery (BA)...
December 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28228722/transcranial-doppler-sonography-reveals-reductions-in-hemispheric-asymmetry-in-healthy-older-adults-during-vigilance
#3
Amanda E Harwood, Pamela M Greenwood, Tyler H Shaw
Given that older adults are remaining longer in the workforce, their ability to perform demanding cognitive tasks such as vigilance assignments needs to be thoroughly examined, especially since many vigilance assignments affect public safety (e.g., aviation, medicine and long distance driving). Previous research exploring the relation between aging and vigilance is conflicted, with some studies finding decreased vigilance performance in older adults but others finding no effect of age. We sought a better understanding of effects of age on vigilance by assessing neurophysiological change over the course of a vigil in young (aged 18-24) and healthy older (aged 66-77) adults...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28227349/automated-embolic-signal-detection-using-adaptive-gain-control-and-classification-using-anfis
#4
Praotasna Sombune, Phongphan Phienphanich, Sombat Muengtaweepongsa, Anuchit Ruamthanthong, Charturong Tantibundhit, Praotasna Sombune, Phongphan Phienphanich, Sombat Muengtaweepongsa, Anuchit Ruamthanthong, Charturong Tantibundhit, Praotasna Sombune, Charturong Tantibundhit, Phongphan Phienphanich, Sombat Muengtaweepongsa, Anuchit Ruamthanthong
This work proposes an automated system for real-time high-accuracy detection of cerebral embolic signals (ES) to couple with transcranial Doppler ultrasound (TCD) devices in diagnosing a risk of stroke. The algorithm employs Adaptive Gain Control (AGC) approach to capture suspected ESs in real-time. Then, Adaptive Wavelet Packet Transform (AWPT) and Fast Fourier Transform (FFT) are used to extract from them features most efficiently representing ES, which determined by Sequential Feature Selection technique...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227290/pre-clinical-investigations-of-multi-path-propagation-in-transcranial-doppler-ultrasound-flow-phantom
#5
Alexander J Weir, Cheng-Xiang Wang, Stuart Parks, Alexander J Weir, Cheng-Xiang Wang, Stuart Parks, Alexander J Weir, Stuart Parks, Cheng-Xiang Wang
There are various practical situations in medical applications when pre-clinical investigations must be performed using a simulation environment or test bench prior to human studies. One example is the analysis of propagation channels in Transcanial Doppler (TCD) ultrasound (US), a signal processing challenge requiring the analysis of data from US waves scattered in three dimensions (3D). When examining the effects of scatterers in such channels, it is common to use a data acquisition test bench and a Doppler flow phantom...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226983/perspective-imaging-of-flow-in-arterial-model-obtained-with-continuous-wave-doppler-focusing-technique
#6
Ryo Nagaoka, Katsuhiro Sasaki, Seiichi Zama, Masaaki Nagone, Hiroshi Nagai, Yasuhito Takeuchi, Yoshifumi Saijo, Ryo Nagaoka, Katsuhiro Sasaki, Seiichi Zama, Masaaki Nagone, Hiroshi Nagai, Yasuhito Takeuchi, Yoshifumi Saijo, Yoshifumi Saijo, Hiroshi Nagai, Katsuhiro Sasaki, Masaaki Nagone, Seiichi Zama, Ryo Nagaoka, Yasuhito Takeuchi
Flowing emboli in the circulatory system cause fatal diseases such as stroke or pulmonary embolism. Conventional transcranial Doppler ultrasound for detection of emboli requires precise positioning by experienced examiner. In the present study, an easier emboli detection device by visualizing perspective view of blood vessel is proposed. The perspective image was obtained with continuous wave (CW) Doppler ultrasound from 2-dimensional array probe. CW Doppler signal from each element was focused by novel beam forming algorithm to obtain en face images at arbitrary depth to form perspective image...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28223258/the-neurologic-protection-of-unilateral-versus-bilateral-antegrade-cerebral-perfusion-in-aortic-arch-surgery-with-deep-hypothermic-circulatory-arrest-a-study-of-77-cases
#7
Bowen Li, Xiaoping Hu, Zhiwei Wang
BACKGROUD: Unilateral and bilateral antegrade cerebral perfusions (ACP) are recognized methods of cerebral protection in aortic arch surgery. However, the adequacy of cerebral protection in aortic arch surgery with deep hypothermic circulatory arrest is controversial. In this study, we compared unilateral and bilateral ACP of cerebral protection in aortic arch surgery by assessing the patient's intraoperative and postoperative brain function. METHODS: A total of 77 patients undergoing aortic arch surgery were included in this study...
February 18, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28220269/is-cerebral-vasomotor-reactivity-impaired-in-parkinson-disease
#8
Martha F Hanby, Ronney B Panerai, Thompson G Robinson, Victoria J Haunton
PURPOSE: The ability of a blood vessel to change diameter in response to a change in carbon dioxide concentration is often referred to as vasomotor reactivity. This study aimed to determine whether vasomotor reactivity is impaired in patients with idiopathic Parkinson's Disease in comparison to healthy controls. METHODS: Transcranial Doppler was used to measure cerebral blood flow velocity in the middle cerebral arteries at baseline and under hypocapnic conditions in 40 patients with idiopathic Parkinson's disease and 50 healthy controls...
February 20, 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/28218603/frequency-and-clinical-course-of-cerebral-embolism-in-patients-undergoing-transcatheter-left-atrial-appendage-closure
#9
Nicolas Majunke, Franziska Eplinius, Matthias Gutberlet, Sven Moebius-Winkler, Ingo Daehnert, Matthias Grothoff, Stephan Schürer, Norman Mangner, Philipp Lurz, Sandra Erbs, Katharina Kirsch, Gerhard Schuler, Marcus Sandri
AIMS: To assess silent and clinically apparent cerebral embolic events in patients undergoing transcatheter left atrial appendage closure. METHODS AND RESULTS: In this prospective single-center study 28 patients underwent percutaneous closure of the left atrial appendage. In all patients a diffusion-weighted magnetic resonance imaging (DWI-MRI) study was performed before, the day after the procedure and during routine follow-up after 45 days. All patients underwent neurological assessment at the time of DWI-MRI...
February 21, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28215461/the-use-of-ultrasound-for-postoperative-monitoring-of-cerebral-bypass-grafts-a-technical-report
#10
Ryan P Morton, Isaac Joshua Abecassis, Anne E Moore, Cory M Kelly, Michael R Levitt, Louis J Kim, Laligam N Sekhar
Duplex ultrasound and transcranial Doppler are valuable tools for post-operative monitoring of extracranial-intracranial cerebral bypass grafts. Here we describe our technique for the evaluation of both high-flow and low-flow cerebral bypass grafts over a nine year period. 186 bypass grafts were studied daily during the inpatient period between Jan 2005 and Dec 2014 after surgery for various cerebrovascular pathologies. There was a technical success rate of 97%. Duplex ultrasonographic flow measurements had excellent interobserver reliability with an intraclass correlation coefficient (ICC) of 0...
February 16, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28215270/decreased-cerebral-vasomotor-reactivity-in-patients-with-obstructive-sleep-apnea-syndrome
#11
Oguzhan Oz, Serdar Tasdemir, Hakan Akgun, Murat Erdem, Adem Balikci, Ahmet Cetiz, Mehmet Yucel, Umit Hidir Ulas, Seref Demirkaya, Yasar Kutukcu, Fuat Özgen
OBJECTIVE: In obstructive sleep apnea syndrome (OSAS), any of the activated neural, vascular, hemodynamic, metabolic, inflammatory, and thrombotic mechanisms may be related to increased cerebrovascular disease and risk of death; however, the possible pathophysiological process between obstructive sleep apnea syndrome and stroke has not been clearly explained. We hypothesize that alterations in vasomotor reactivity in patients may be responsible for their altered cerebral blood flow, and may contribute to the increased risk of ischemic stroke...
February 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28214128/robotic-arch-catheter-placement-reduces-cerebral-embolization-during-thoracic-endovascular-aortic-repair-tevar
#12
A H Perera, C V Riga, L Monzon, R G Gibbs, C D Bicknell, M Hamady
OBJECTIVE: Stroke caused by cerebral embolization constitutes a principal risk during arch manipulation and thoracic endovascular aortic repair (TEVAR). This study investigates the incidence of cerebral embolization during catheter placement in the aortic arch, and compares robotic and manual techniques. METHODS: Intra-operative transcranial Doppler (TCD) was performed in 11 patients undergoing TEVAR. Wire and catheter placement in the arch was performed by two experienced operators...
February 14, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28207907/argon-does-not-affect-cerebral-circulation-or-metabolism-in-male-humans
#13
Frank Grüne, Stephan Kazmaier, Sanne Elisabeth Hoeks, Robert Jan Stolker, Marc Coburn, Andreas Weyland
OBJECTIVE: Accumulating data have recently underlined argon´s neuroprotective potential. However, to the best of our knowledge, no data are available on the cerebrovascular effects of argon (Ar) in humans. We hypothesized that argon inhalation does not affect mean blood flow velocity of the middle cerebral artery (Vmca), cerebral flow index (FI), zero flow pressure (ZFP), effective cerebral perfusion pressure (CPPe), resistance area product (RAP) and the arterio-jugular venous content differences of oxygen (AJVDO2), glucose (AJVDG), and lactate (AJVDL) in anesthetized patients...
2017: PloS One
https://www.readbyqxmd.com/read/28204998/discrimination-between-emboli-and-artifacts-for-outpatient-transcranial-doppler-ultrasound-data
#14
Blaise Kévin Guépié, Bruno Sciolla, Fabien Millioz, Marilys Almar, Philippe Delachartre
This paper addresses the detection of emboli in transcranial Doppler ultrasound data acquired from an original portable device. The challenge is the removal of several artifacts (motion and voice) intrinsically related to long-duration (up to 1 h 40 mn per patient) outpatient signals monitoring from this device, as well as high intensities due to the stochastic nature of blood flow. This paper proposes an adapted removal procedure. This firstly consists of reducing the background noise and detecting the blood flow in the time-frequency domain using a likelihood method for contour detection...
February 15, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/28203558/cerebral-monitoring-during-carotid-endarterectomy-by-transcranial-doppler-ultrasonography
#15
Woo-Sung Yun
PURPOSE: To evaluate the efficacy and safety of cerebral monitoring by transcranial Doppler ultrasonography (TCD) for the detection of cerebral ischemia during carotid endarterectomy (CEA). METHODS: From August 2004 to December 2013, 159 CEAs were performed in a tertiary hospital. All procedures were performed under general anesthesia. Intraoperative TCD was routinely used to detect cerebral ischemia. Of the 159 patients, 102 patients were included in this study, excluding 27 patients who had a poor transtemporal isonation window and 30 patients who used additional cerebral monitoring systems such as electroencephalography or somatosensory evoked potentials...
February 2017: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/28199523/detection-and-differentiation-of-cerebral-microemboli-in-patients-undergoing-major-orthopaedic-surgery-using-transcranial-doppler-ultrasound
#16
C Kietaibl, A Engel, I Horvat Menih, M Huepfl, G Erdoes, B Kubista, R Ullrich, R Windhager, K Markstaller, K U Klein
No abstract text is available yet for this article.
February 10, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/28193836/post-subdural-hematoma-transient-ischemic-attacks-hypoperfusion-mechanism-supported-by-quantitative-electroencephalography-and-transcranial-doppler-sonography
#17
Ayham M Alkhachroum, Guadalupe Fernandez-Baca Vaca, Sophia Sundararajan, Michael DeGeorgia
No abstract text is available yet for this article.
February 13, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28188214/transcranial-doppler-determined-change-in-posterior-cerebral-artery-blood-flow-velocity-does-not-reflect-vertebral-artery-blood-flow-during-exercise
#18
Takuro Washio, Hiroyuki Sasaki, Shigehiko Ogoh
We examined whether a change in posterior cerebral artery flow velocity (PCAv) reflected the posterior cerebral blood flow, in healthy subjects, during both static and dynamic exercise. PCAv and vertebral artery (VA) blood flow, as an index of posterior blood flow, were continuously measured during an exercise trial, using transcranial Doppler (TCD) ultrasonography and Doppler ultrasound, respectively. Static handgrip exercise significantly increased both PCAv and VA blood flow. Increasing intensity of dynamic exercise further increased VA blood flow from moderate exercise, while PCAv decreased to almost resting level...
February 10, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/28187816/multimodal-neurologic-monitoring
#19
G Korbakis, P M Vespa
Neurocritical care has two main objectives. Initially, the emphasis is on treatment of patients with acute damage to the central nervous system whether through infection, trauma, or hemorrhagic or ischemic stroke. Thereafter, attention shifts to the identification of secondary processes that may lead to further brain injury, including fever, seizures, and ischemia, among others. Multimodal monitoring is the concept of using various tools and data integration to understand brain physiology and guide therapeutic interventions to prevent secondary brain injury...
2017: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/28185829/a-systematic-review-of-the-literature-for-severity-predictors-in-children-with-sickle-cell-anemia
#20
Emily Riehm Meier, Ross M Fasano, Paul R Levett
All patients with HbSS (SCA) share the same genetic mutation but the clinical phenotype is variable and difficult to predict early in life. A reliable severity predictor would be invaluable toward directing therapeutic decisions in those patients at highest risk of SCA complications. A search of PubMed, Cochrane Clinical Trials Register, and Scopus was performed to determine which SCA severity predictors have been validated in pediatric patients. The full text of 94 of the 590 references identified was reviewed based on the title/abstract...
February 2, 2017: Blood Cells, Molecules & Diseases
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