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https://www.readbyqxmd.com/read/29334161/the-role-of-neurosonology-in-the-diagnosis-and-management-of-patients-with-carotid-artery-disease-a-review
#1
REVIEW
Odysseas Kargiotis, Apostolos Safouris, Georgios Magoufis, Maria Georgala, Andromachi Roussopoulou, Eleftherios Stamboulis, Konstantinos G Moulakakis, Andreas Lazaris, George Geroulakos, Spyros Vasdekis, Georgios Tsivgoulis
Carotid artery disease (CAD) is a common cause of ischemic stroke with high rates of recurrence. Carotid endarterectomy (CEA) or carotid artery stenting (CAS) are highly recommended for the secondary prevention of symptomatic CAD during the first 14 days following the index event of transient ischemic attack or minor stroke. CEA or CAS may also be offered in selected cases with severe asymptomatic stenosis. Herein, we review the utility of neurosonology in the diagnosis and pre-/peri-interventional assessment of CAD patients who undergo carotid revascularization procedures...
January 15, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29333343/resounding-failure-to-replicate-links-between-developmental-language-disorder-and-cerebral-lateralisation
#2
Alexander C Wilson, Dorothy V M Bishop
Background: It has been suggested that failure to establish cerebral lateralisation may be related to developmental language disorder (DLD). There has been weak support for any link with handedness, but more consistent reports of associations with functional brain lateralisation for language. The consistency of lateralisation across different functions may also be important. We aimed to replicate previous findings of an association between DLD and reduced laterality on a quantitative measure of hand preference (reaching across the midline) and on language laterality assessed using functional transcranial Doppler ultrasound (fTCD)...
2018: PeerJ
https://www.readbyqxmd.com/read/29315509/carotid-plaque-volume-in-patients-undergoing-carotid-endarterectomy
#3
S Ball, S Rogers, K Kanesalingam, R Taylor, E Katsogridakis, C McCollum
BACKGROUND: The main indication for carotid endarterectomy (CEA) is severity of carotid artery stenosis, even though most strokes in carotid disease are embolic. The relationship between carotid plaque volume (CPV) and symptoms of cerebral ischaemia, and the measurement of CPV by minimally invasive tomographic ultrasound imaging, were investigated. METHODS: The volume of the endarterectomy specimen was measured using a validated saline suspension technique in patients undergoing CEA...
January 8, 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29305914/the-comparison-of-monitoring-of-cerebral-blood-flow-by-c-flow-and-transcranial-doppler-in-carotid-endarterectomy
#4
Xu Wang, Bin Yang, Yan Ma, Peng Gao, Yabing Wang, Yanfei Chen, Liqun Jiao, Feng Ling, Guoguang Zhao
OBJECTIVE: To prospectively compare the use of the c-FLOW (cerebral blood flow monitor) and transcranial Doppler (TCD) as two techniques for assessing brain perfusion during carotid endarterectomy (CEA). METHODS: This was a prospective, single center, observational study. All patients were monitored using c-FLOW and TCD during the operation. Changes from baseline values of cerebral blood flow index (CFI) and blood flow velocity of middle cerebral artery (V-MCA) were recorded following carotid artery clamping and unclamping...
January 3, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29302799/early-abnormal-transient-hyperemic-response-test-can-predict-delayed-ischemic-neurologic-deficit-in-subarachnoid-hemorrhage
#5
Hosam Al-Jehani, Mark Angle, Judith Marcoux, Jeanne Teitelbaum
BACKGROUND: Early detection of vasospasm is crucial to prevent significant delayed ischemic neurological deficit post subarachnoid hemorrhage. The standard methods of detection, including cerebral angiogram and computed tomography are invasive and not safe to be repeated, as is very often indicated clinically. Transient hyperemic response test has been previously used to predict autoregulation failure in traumatic brain injury and subarachnoid hemorrhage. AIMS: We investigate the usability of transient hyperemic response test as a predictor of clinical vasospasm in a cohort of patients with aneurismal subarachnoid hemorrhage...
January 4, 2018: Critical Ultrasound Journal
https://www.readbyqxmd.com/read/29285410/the-clinical-examination-in-the-patient-with-subarachnoid-hemorrhage-is-still-the-most-reliable-parameter-for-predicting-pathophysiological-changes
#6
Athanasios K Petridis, Kerim Beseoglu, Hans J Steiger
Background: Macrovasospasms and delayed cerebral injury are factors which correlate with high morbidity in patients suffering a subarachnoid hemorrhage. Transcranial Doppler (TCD) ultrasonography and perfusion computed tomography (PCT) are diagnostic tools used to diagnose such pathologies. However, TCD is not very reliable and PCT exposes patients to radiation and cannot be performed daily. Case Description: We present the case of a 47-year-old female with subarachnoid hemorrhage caused by rupture of an intracranial aneurysm...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/29282326/neurocognitive-functioning-and-cerebrovascular-reactivity-after-carotid-endarterectomy
#7
Simona Lattanzi, Luciano Carbonari, Gabriele Pagliariccio, Marco Bartolini, Claudia Cagnetti, Giovanna Viticchi, Laura Buratti, Leandro Provinciali, Mauro Silvestrini
OBJECTIVE: To evaluate in patients with TIA and ipsilateral high-grade internal carotid artery (ICA) stenosis whether changes in cognitive performance and cerebral hemodynamics occurred after carotid endarterectomy (CEA) and to explore their relationship. METHODS: Participants were patients who underwent CEA, had TIA within the last 6 months, and had an ipsilateral severe ICA stenosis. Coloured Progressive Matrices (CPM) plus Complex Figure Copy Test (CFCT) and phonemic (ph) plus categorical (ca) Verbal Fluency (VF) tests were performed to assess right and left hemisphere cognitive functions, respectively...
December 27, 2017: Neurology
https://www.readbyqxmd.com/read/29280236/advanced-pediatric-neurosonography-techniques-contrast-enhanced-ultrasonography-elastography-and-beyond
#8
REVIEW
Misun Hwang, Becky J Riggs, Joseph Katz, Donna Seyfert, Frances Northington, Robinson Shenandoah, Irina Burd, Justin McArthur, Kassa Darge, Matthew A Thimm, Thierry A G M Huisman
Recent technical advances in neurosonography continue broadening the diagnostic utility, sensitivity, and specificity of ultrasound for detecting intracranial abnormalities bed side. The clinical and functional applications of neurosonography have significantly expanded since the 1980s when transcranial Doppler sonography first allowed anatomic and hemodynamic delineation of the intracranial vessels through the thin temporal skull. In the past few years, contrast-enhanced ultrasonography, elastography, 3D/4D reconstruction tools, and high-resolution microvessel imaging techniques have further enhanced the diagnostic significance of neurosonography...
December 27, 2017: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://www.readbyqxmd.com/read/29279888/prevalence-of-systemic-atherosclerosis-burdens-and-overlapping-stroke-etiologies-and-their-associations-with-long-term-vascular-prognosis-in-stroke-with-intracranial-atherosclerotic-disease
#9
Takao Hoshino, Leila Sissani, Julien Labreuche, Gregory Ducrocq, Philippa C Lavallée, Elena Meseguer, Céline Guidoux, Lucie Cabrejo, Cristina Hobeanu, Fernando Gongora-Rivera, Pierre-Jean Touboul, Philippe Gabriel Steg, Pierre Amarenco
Importance: Patients who have experienced stroke with intracranial atherosclerotic disease (ICAD) may also have concomitant atherosclerosis in different arterial beds and other possible causes for ischemic stroke. However, little is known about the frequency and prognostic effect of such overlapping diseases. Objectives: To describe the prevalence of systemic atherosclerotic burdens and overlapping stroke etiologies and their contributions to long-term prognoses among patients who have experienced stroke with ICAD...
December 26, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/29262436/multimodality-monitoring-toward-improved-outcomes
#10
Richard Gandee, Chad Miller
Multimodality monitoring provides insights into the critically ill brain-injured patient through the assessment of biochemical, physiological, and electrical data that provides insight into a patient's condition and what strategies may be available to limit further damage and improve the odds for recovery. Modalities utilized include evaluation of intracranial pressure along with cerebral perfusion pressure to determine adequate blood flow; continuous electroencephalography to protect the patient from seizures and to identify early functional manifestations of ischemia and toxicity; transcranial Doppler evaluation for bedside review of circulatory adequacy; tissue oxygen monitoring to establish that brain tissue is receiving adequate oxygen from blood flow; and microdialysis to evaluate the metabolic function of the tissue in areas of concern...
December 2017: Seminars in Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29251634/the-clinical-implication-of-transcranial-doppler-detection-of-microembolic-signals-in-patients-with-heartmate-ii
#11
Kazuki Fukuma, Osamu Seguchi, Kozue Saito, Kensuke Kuroda, Seiko Nakajima, Takuma Sato, Masanobu Yanase, Yorihiko Matsumoto, Satsuki Fukushima, Tomoyuki Fujita, Junjiro Kobayashi, Kazuyuki Nagatsuka, Norihide Fukushima
We aimed to elucidate the clinical relevance of transcranial Doppler (TCD) in the detection of microembolic signals in patients with Heartmate II (HM-II). Twenty patients with HM-II underwent TCD examinations, and microembolic signals were rarely detected in stable patients. However, they were detected in patients with hemolysis and/or thromboembolic events. Further, TCD examination under oxygen inhalation revealed that, both, solid emboli and gaseous emboli exist in patients with HM-II.
December 14, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29247032/thromboembolic-risks-of-the-procedural-process-in-second-generation-cryoballoon-ablation-procedures-analysis-from-real-time-transcranial-doppler-monitoring
#12
Shinsuke Miyazaki, Tomonori Watanabe, Takatsugu Kajiyama, Jin Iwasawa, Sadamitsu Ichijo, Hiroaki Nakamura, Hiroshi Taniguchi, Kenzo Hirao, Yoshito Iesaka
BACKGROUND: Atrial fibrillation ablation is associated with substantial risks of silent cerebral events (SCEs) or silent cerebral lesions. We investigated which procedural processes during cryoballoon procedures carried a risk. METHODS AND RESULTS: Forty paroxysmal atrial fibrillation patients underwent pulmonary vein isolation using second-generation cryoballoons with single 28-mm balloon 3-minute freeze techniques. Microembolic signals (MESs) were monitored by transcranial Doppler throughout all procedures...
December 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29244749/serum-levels-of-s100b-and-nse-proteins-in-patients-with-non-transfusion-dependent-thalassemia-as-biomarkers-of-brain-ischemia-and-cerebral-vasculopathy
#13
Aikaterini Kanavaki, Konstantinos Spengos, Maria Moraki, Polyxeni Delaporta, Catherine Kariyannis, Ioannis Papassotiriou, Antonis Kattamis
Patients with non-transfusion-dependent thalassemia (NTDT) are at risk of developing brain ischemia. Transcranial Doppler (TCD) has been established as a useful screening tool of cerebrovascular disease in patients with sickle cell disease. Proteins neuron specific enolase (NSE) and S100B are biomarkers that reflect CNS injury. The purpose of this study is to evaluate cerebral vessel vasculopathy and brain damage in NTDT patients using non-invasive methods as TCD and measurement serum levels of NSE and S100B...
December 15, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29239696/compression-garments-and-cerebral-blood-flow-influence-on-cognitive-and-exercise-performance
#14
Brittany A Smale, Joseph M Northey, Disa J Smee, Nathan G Versey, Ben Rattray
This study aimed to describe the effect of compression garments on middle cerebral artery blood flow velocity (MCAv) in relation to cognitive and exercise performance whilst cycling. In a randomised-controlled-cross-over design, 15 well-trained male cyclists were recruited to participate in three identical trials wearing loose fitting shorts (control), low-grade, or medium-grade compression garments. The protocol involved four 8 min increments of cycling at 30%, 50%, 70%, and 85% maximal power output and a 4 km time-trial...
December 14, 2017: European Journal of Sport Science
https://www.readbyqxmd.com/read/29234612/near-infrared-spectroscopy-versus-transcranial-doppler-based-monitoring-in-carotid-endarterectomy
#15
Jun Woo Cho, Jae Seok Jang
Background: Proper monitoring of cerebral perfusion during carotid artery surgery is crucial for determining if a shunt is needed. We compared the safety and reliability of near-infrared spectroscopy (NIRS) with transcranial Doppler (TCD) for cerebral monitoring. Methods: This single-center, retrospective review was conducted on patients who underwent carotid endarterectomy (CEA) using selective shunt-based TCD or NIRS at Daegu Catholic University Medical Center from November 2009 to June 2016...
December 2017: Korean Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29231781/dynamic-autoregulation-of-cerebral-blood-flow-measured-non-invasively-with-fast-diffuse-correlation-spectroscopy
#16
Ashwin B Parthasarathy, Kimberly P Gannon, Wesley B Baker, Christopher G Favilla, Ramani Balu, Scott E Kasner, Arjun G Yodh, John A Detre, Michael T Mullen
Cerebral autoregulation (CA) maintains cerebral blood flow (CBF) in the presence of systemic blood pressure changes. Brain injury can cause loss of CA and resulting dysregulation of CBF, and the degree of CA impairment is a functional indicator of cerebral tissue health. Here, we demonstrate a new approach to noninvasively estimate cerebral autoregulation in healthy adult volunteers. The approach employs pulsatile CBF measurements obtained using high-speed diffuse correlation spectroscopy (DCS). Rapid thigh-cuff deflation initiates a chain of responses that permits estimation of rates of dynamic autoregulation in the cerebral microvasculature...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/29219028/ambulatory-pulse-pressure-brain-neuronal-fiber-integrity-and-cerebral-blood-flow-in-older-adults
#17
Takashi Tarumi, Binu P Thomas, Ciwen Wang, Li Zhang, Jie Liu, Marcel Turner, Jonathan Riley, Nikita Tangella, Kyle B Womack, Diana R Kerwin, C Munro Cullum, Hanzhang Lu, Wanpen Vongpatanasin, David C Zhu, Rong Zhang
Ambulatory blood pressure (ABP) reflects the end-organ vascular stress in daily life; however, its influence on brain neuronal fiber integrity and cerebral blood flow (CBF) remains unclear. The objective of this study was to determine the associations among ABP, white matter (WM) neuronal fiber integrity, and CBF in older adults. We tested 144 participants via ABP monitoring and diffusion tensor imaging. The total level and pulsatile indices of CBF were measured by phase-contrast MRI and transcranial Doppler, respectively...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/29212807/the-independent-and-interactive-effects-of-incremental-heat-strain-orthostatic-stress-and-mild-hypohydration-on-cerebral-perfusion
#18
Rebekah A I Lucas, Luke C Wilson, Philip N Ainslie, Jui-Lin Fan, Kate N Thomas, James D Cotter
The purpose of this study was to identify the dose-dependent effects of heat strain and orthostasis (via lower-body negative pressure; LBNP), with and without mild hypohydration, on systemic function and cerebral perfusion. Eleven males (Mean ±SD: 27 ±7 y; body mass 77 ±6 kg), resting supine in a water-perfused suit, underwent progressive passive heating [0.5°C increments in core temperature (Tc, oesophageal to +2.0°C)] whilst euhydrated (EUH) or hypohydrated (HYPO, 1.5-2% body mass deficit). At each thermal state, mean cerebral artery blood velocity (MCAvmean, Transcranial Doppler), partial pressure of end-tidal carbon dioxide (PETCO2), heart rate (HR) and mean arterial blood pressure (MAP, photoplethysmography) were measured continuously during LBNP (0, -15, -30, -45 mm Hg)...
December 6, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/29201539/assessment-of-cerebral-blood-flow-with-magnetic-resonance-imaging-in-children-with-sickle-cell-disease-a-quantitative-comparison-with-transcranial-doppler-ultrasonography
#19
Paula L Croal, Jackie Leung, Przemyslaw Kosinski, Manohar Shroff, Isaac Odame, Andrea Kassner
Introduction: Transcranial Doppler ultrasonography (TCD) is a clinical tool for stratifying ischemic stroke risk by identifying abnormal elevations in blood flow velocity (BFV) in the middle cerebral artery (MCA). However, TCD is not effective at screening for subtle neurologic injury such as silent cerebral infarcts. To better understand this disparity, we compared TCD measures of BFV with tissue-level cerebral blood flow (CBF) using arterial spin-labeling MRI in children with and without sickle cell disease, and correlated these measurements against clinical hematologic measures of disease severity...
November 2017: Brain and Behavior
https://www.readbyqxmd.com/read/29195161/prenatal-and-pubertal-testosterone-affect-brain-lateralization
#20
T Beking, R H Geuze, M van Faassen, I P Kema, B P C Kreukels, T G G Groothuis
After decades of research, the influence of prenatal testosterone on brain lateralization is still elusive, whereas the influence of pubertal testosterone on functional brain lateralization has not been investigated, although there is increasing evidence that testosterone affects the brain in puberty. We performed a longitudinal study, investigating the relationship between prenatal testosterone concentrations in amniotic fluid, pubertal testosterone concentrations in saliva, and brain lateralization (measured with functional Transcranial Doppler ultrasonography (fTCD)) of the Mental Rotation, Chimeric Faces and Word Generation tasks...
November 6, 2017: Psychoneuroendocrinology
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