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https://www.readbyqxmd.com/read/27882320/mediterrasian-diet-products-that-could-raise-hdl-cholesterol-a-systematic-review
#1
REVIEW
Mariangela Rondanelli, Attilio Giacosa, Paolo Morazzoni, Davide Guido, Mario Grassi, Gabriella Morandi, Chiara Bologna, Antonella Riva, Pietro Allegrini, Simone Perna
Background. High HDL-cholesterol (HDL-C) values are negatively correlated with cardiovascular diseases. This review analyses the effect of the supplementation with various Mediterranean diet products (artichoke, bergamot, and olive oil) and Asian diet products (red yeast rice) on the HDL-C value in dyslipidemic subjects. Methods. A systematic review has been done involving all the English written studies published from the 1st of January 1958 to the 31st of March 2016. Results. The results of this systematic review indicate that the dietary supplementation with red yeast rice, bergamot, artichoke, and virgin olive oil has promising effects on the increase of HDL-C serum levels...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27877148/changes-in-mood-states-are-induced-by-smelling-familiar-and-exotic-fragrances
#2
Orly Sarid, Michele Zaccai
Familiar fragrances usually induce positive mood states and elicit favorable evaluation. Relaxation is also widely thought to improve mood state. Yet experimental evidence on the effect of two different stimuli, fragrance smelling and breathing relaxation, on mood state, and fragrance evaluation is lacking. This study aimed to test (1) the effect of two familiar fragrances, lavender and myrtle, and two exotic fragrances, bergamot and ravensara, on perceived mood states before and after relaxation, (2) the effect of relaxation on perceived mood states for each fragrance, and (3) the effect of relaxation on fragrance evaluation as defined by adjectives...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27857849/in-vitro-effect-of-seven-essential-oils-on-the-reproduction-of-the-cattle-tick-rhipicephalus-microplus
#3
Rafael Pazinato, Andréia Volpato, Matheus D Baldissera, Roberto C V Santos, Dilmar Baretta, Rodrigo A Vaucher, Janice L Giongo, Aline A Boligon, Lenita Moura Stefani, Aleksandro Schafer Da Silva
The acaricidal effect of seven essential oils was examined in vitro against the cattle tick (Rhipicephalus microplus). Engorged female ticks were manually collected in farms of Southern Brazil and placed into petri dishes (n = 10) in order to test the following oils: juniper (Juniperus communis), palmarosa (Cymbopogon martinii), cedar (Cedrus atlantica), lemon grass (Cymbopogon citratus), ginger (Zingiber officinale), geranium (Pelargonium graveolens) and bergamot (Citrus aurantium var bergamia) at concentrations of 1%, 5%, and 10% each...
November 2016: Journal of Advanced Research
https://www.readbyqxmd.com/read/27846426/metabolic-outcomes-of-bergamot-polyphenolic-fraction-administration-in-patients-treated-with-second-generation-antipsychotics-a-pilot-study
#4
Antonio Bruno, Gianluca Pandolfo, Manuela Crucitti, Antonino Maisano, Rocco A Zoccali, Maria Rosaria Anna Muscatello
Second-generation antipsychotics (SGAs) are notoriously associated with a marked increase in body weight and with a wide range of metabolic adverse effects, and their chronic use is related with an increased risk for the development of metabolic syndrome (MS). Different adjunctive treatments have been proposed to reduce SGAs-induced weight gain and/or metabolic abnormalities with inconsistent or too limited evidence to support their regular clinical use, thus suggesting the need to find new possible treatments...
October 22, 2016: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/27845763/the-chemistry-and-pharmacology-of-citrus-limonoids
#5
REVIEW
Roberta Gualdani, Maria Maddalena Cavalluzzi, Giovanni Lentini, Solomon Habtemariam
Citrus limonoids (CLs) are a group of highly oxygenated terpenoid secondary metabolites found mostly in the seeds, fruits and peel tissues of citrus fruits such as lemons, limes, oranges, pumellos, grapefruits, bergamots, and mandarins. Represented by limonin, the aglycones and glycosides of CLs have shown to display numerous pharmacological activities including anticancer, antimicrobial, antioxidant, antidiabetic and insecticidal among others. In this review, the chemistry and pharmacology of CLs are systematically scrutinised through the use of medicinal chemistry tools and structure-activity relationship approach...
November 13, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27755863/adverse-phototoxic-effect-of-essential-plant-oils-on-nih-3t3-cell-line-after-uv-light-exposure
#6
Svatopluk Binder, Adéla Hanáková, Kateřina Tománková, Klára Pížová, Robert Bajgar, Barbora Manišová, Kristina Kejlová, Hana Bendová, Dagmar Jírová, Hana Kolářová
AIM: Natural or artificial substances have become an inseparable part of our lives. It is questionable whether adequate testing has been performed in order to ensure these substances do not pose a serious health risk. The principal aim of our research was to clarify the potential risk of adding essential oils to food, beverages and cosmetic products. METHODS: The toxicity of substances frequently employed in cosmetics, aromatherapy and food industry (bergamot oil, Litsea cubeba oil, orange oil, citral) were investigated using cell line NIH3T3 (mouse fibroblasts) with/without UV irradiation...
September 2016: Central European Journal of Public Health
https://www.readbyqxmd.com/read/27747942/clinical-pharmacology-of-citrus-bergamia-a-systematic-review
#7
Carmen Mannucci, Michele Navarra, Fabrizio Calapai, Raffaele Squeri, Sebastiano Gangemi, Gioacchino Calapai
Citrus bergamia Risso et Poiteau ("Bergamot") originated from the Mediterranean ecoregion (southern Italy, Calabria). Bergamot essential oil (BEO) is used in perfumes, cosmetics, and for stress reduction. Juice from C. bergamia has been used for hyperlipidemia. We evaluated literature published on C. bergamia clinical applications. Clinical trials on C. bergamia not combined with other substances, published in English, were searched. We selected ten articles, six describing BEO effects on stress, three reporting effects of polyphenolic fraction of C...
October 17, 2016: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/27669206/anti-inflammatory-activity-of-citrus-bergamia-derivatives-where-do-we-stand
#8
REVIEW
Nadia Ferlazzo, Santa Cirmi, Gioacchino Calapai, Elvira Ventura-Spagnolo, Sebastiano Gangemi, Michele Navarra
Inflammatory diseases affect a large portion of the worldwide population, and chronic inflammation is a major risk factor for several dangerous pathologies. To limit the side effects of both synthetic and biological anti-inflammatory drugs, the use of herbal medicines, nutraceuticals and food supplements has increased tremendously as alternative and/or complementary medicine to treat several pathologies, including inflammation. During the last decades, the biological properties of Citrus bergamia (bergamot) derivatives have obtained important scientific achievements, and it has been suggested their use in a context of a multitarget pharmacological strategy...
2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27570269/effect-of-uv-c-radiation-and-vapor-released-from-a-water-hyacinth-root-absorbent-containing-bergamot-oil-to-control-mold-on-storage-of-brown-rice
#9
Sumethee Songsamoe, Narumol Matan, Nirundorn Matan
The aims of this study were to develop absorbent material from a water hyacinth root containing bergamot oil and to improve its antifungal activity by using ultraviolet C (UV-C) against the growth of A. flavus on the brown rice. Process optimization was studied by the immersion of a water hyacinth root into a water and bergamot oil (300, 500 and 700 μl ml(-1)). The root (absorbent material) was dried at 50, 70, and 90 °C for 10 min. Then, ultraviolet C (UV-C) was used for enhancing the antifungal activity of bergamot oil for 10, 15, and 20 min...
March 2016: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/27471464/anti-inflammatory-and-antioxidant-effects-of-flavonoid-rich-fraction-of-bergamot-juice-bje-in-a-mouse-model-of-intestinal-ischemia-reperfusion-injury
#10
Daniela Impellizzeri, Marika Cordaro, Michela Campolo, Enrico Gugliandolo, Emanuela Esposito, Filippo Benedetto, Salvatore Cuzzocrea, Michele Navarra
The flavonoid-rich fraction of bergamot juice (BJe) has demonstrated anti-inflammatory and antioxidant activities. The aim of work was to test the beneficial effects of BJe on the modulation of the ileum inflammation caused by intestinal ischemia/reperfusion (I/R) injury in mice. To understand the cellular mechanisms by which BJe may decrease the development of intestinal I/R injury, we have evaluated the activation of signaling transduction pathways that can be induced by reactive oxygen species production...
2016: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/27463949/synergistic-in-vitro-antioxidant-activity-and-observational-clinical-trial-of-f105-a-phytochemical-formulation-including-citrus-bergamia-in-subjects-with-moderate-cardiometabolic-risk-factors
#11
John G Babish, Clinton J Dahlberg, Joseph J Ou, William J Keller, Wei Gao, Mohan R Kaadige, Holly Brabazon, Joseph Lamb, Hani C Soudah, Xiaolan Kou, Zhe Zhang, Linda M Pacioretty, Matthew L Tripp
We examined the clinical safety and efficacy of F105 in 11 subjects with moderate dyslipidemia. F105 is a combination of bergamot fruit extract (Citrus bergamia, BFE) and 9 phytoextracts selected for their ability to improve the antioxidant and anti-inflammatory activity of BFE. In vitro F105 exhibited a synergistic inhibition of oxygen radical absorbing capacity, peroxynitrite formation, and myeloperoxidase activity. Following 12 weeks of F105 daily, no treatment-related adverse events or changes in body mass were seen...
May 31, 2016: Canadian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/27460885/rapid-discrimination-of-bergamot-essential-oil-by-paper-spray-mass-spectrometry-and-chemometric-analysis
#12
Domenico Taverna, Leonardo Di Donna, Fabio Mazzotti, Antonio Tagarelli, Anna Napoli, Emilia Furia, Giovanni Sindona
A novel approach for the rapid discrimination of bergamot essential oil from other citrus fruits oils is presented. The method was developed using paper spray mass spectrometry (PS-MS) allowing for a rapid molecular profiling coupled with a statistic tool for a precise and reliable discrimination between the bergamot complex matrix and other similar matrices, commonly used for its reconstitution. Ambient mass spectrometry possesses the ability to record mass spectra of ordinary samples, in their native environment, without sample preparation or pre-separation by creating ions outside the instrument...
September 2016: Journal of Mass Spectrometry: JMS
https://www.readbyqxmd.com/read/27246183/multimodal-interaction-in-the-insect-brain
#13
Anna Balkenius, Christian Balkenius
BACKGROUND: The magnitude of multimodal enhancement in the brain is believed to depend on the stimulus intensity and timing. Such an effect has been found in many species, but has not been previously investigated in insects. RESULTS: We investigated the responses to multimodal stimuli consisting of an odour and a colour in the antennal lobe and mushroom body of the moth Manduca sexta. The mushroom body shows enhanced responses for multimodal stimuli consisting of a general flower odour and a blue colour...
2016: BMC Neuroscience
https://www.readbyqxmd.com/read/27227548/inhibition-of-spinal-oxidative-stress-by-bergamot-polyphenolic-fraction-attenuates-the-development-of-morphine-induced-tolerance-and-hyperalgesia-in-mice
#14
Filomena Lauro, Luigino Antonio Giancotti, Sara Ilari, Concetta Dagostino, Micaela Gliozzi, Chiara Morabito, Valentina Malafoglia, William Raffaeli, Maurizio Muraca, Bianca M Goffredo, Vincenzo Mollace, Carolina Muscoli
Citrus Bergamia Risso, commonly known as Bergamot, is a fruit whose Essential Oil and Bergamot Polyphenolic Fraction have numerous medicinal properties. It is also an excellent antioxidant and in this study, for the first time, its potential effect on morphine induced tolerance in mice has been investigated. Our studies revealed that development of antinociceptive tolerance to repeated doses of morphine in mice is consistently associated with increased formation of superoxide, malondialdehyde and tyrosine-nitrated proteins in the dorsal horn of the spinal cord such as the enzyme glutamine synthase...
2016: PloS One
https://www.readbyqxmd.com/read/27218799/anti-infective-potential-of-citrus-bergamia-risso-et-poiteau-bergamot-derivatives-a-systematic-review
#15
REVIEW
Santa Cirmi, Carlo Bisignano, Giuseppina Mandalari, Michele Navarra
Infectious diseases remain among the leading causes of morbidity and mortality worldwide, mainly because of the increase of resistance to chemotherapeutic drugs. Nature is the major source of anti-infective drugs and could represent a font of medicines that may help overcome antibiotic resistance. Recently, the potential antimicrobial effect of certain plant extracts has attracted attention within the scientific community as alternatives to synthetic drugs. Here, we present a systematic review on the anti-infective properties of bergamot derivatives that highlight the activity of bergamot essential oil against bacteria, mycetes and larvae, as well as the anti-Helicobacter pylori effect of bergamot juice and the antimicrobial properties of extracts from bergamot peel...
September 2016: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/27136257/characterization-of-radicals-arising-from-oxidation-of-commercially-important-essential-oils
#16
Hiroko-Miyuki Mori, Hideo Iwahashi
Inappropriate use of essential oils may entail risks to human health due to mutational events, carcinogenic effects, genetic damages and sensitizing effect caused by generation of reactive oxygen species. In order to detect radicals that are expected to form during their oxidation, we measured the electron spin resonance (ESR) spectra of a standard reaction mixture (I) containing 25 μM flavin mononucleotide, 0.018% several essential oils (or 0.015% geraniol), 1.9 M acetonitrile, 20 mM phosphate buffer (pH 7...
June 2016: Free Radical Research
https://www.readbyqxmd.com/read/27041320/oxygenated-heterocyclic-compounds-to-differentiate-citrus-spp-essential-oils-through-metabolomic-strategies
#17
Jerome Masson, Erica Liberto, Jean-Claude Beolor, Hugues Brevard, Carlo Bicchi, Patrizia Rubiolo
This study aimed to characterise and discriminate 44 authenticated commercial samples of citrus essential oils (EO) from seven species (bergamot, lemon, bigarade, orange, mandarin, grapefruit, lime) by analysing the non-volatile oxygenated heterocyclic compounds (OHC) by UHPLC/TOF-HRMS, multivariate data analysis (PCA, PLS-DA) and metabolomic strategies; the OHC fraction includes coumarins, furocoumarins, and polymethoxylated flavonoids. Two different approaches were adopted: (i) targeted profiling based on quantifying 18 furocoumarins and coumarins, some of which are regulated by law, and (ii) targeted fingerprinting based on 140 OHCs reported in citrus essential oils, from which 38 discriminant markers were defined...
September 1, 2016: Food Chemistry
https://www.readbyqxmd.com/read/27037654/natural-iron-chelators-protective-role-in-a549-cells-of-flavonoids-rich-extracts-of-citrus-juices-in-fe-3-induced-oxidative-stress
#18
Nadia Ferlazzo, Giuseppa Visalli, Santa Cirmi, Giovanni Enrico Lombardo, Pasqualina Laganà, Angela Di Pietro, Michele Navarra
Exogenous iron in particulate matter and imbalanced iron homeostasis cause deleterious effects on health. Natural and synthetic iron chelators may be of therapeutic benefit, therefore we evaluated the protective effect of Citrus flavonoids-rich extracts from bergamot and orange juices in iron overloaded human lung epithelial cells. Cytofluorimetric, biochemical and genotoxic analyses were performed in Fe2(SO4)3 exposed A549, pretreated with each extract whose chemical composition was previously detected. Chelating activity was assessed in cells by a calcein ester...
April 2016: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/26996621/rational-basis-for-the-use-of-bergamot-essential-oil-in-complementary-medicine-to-treat-chronic-pain
#19
L Rombolà, D Amantea, R Russo, A Adornetto, L Berliocchi, L Tridico, M T Corasaniti, S Sakurada, T Sakurada, G Bagetta, L A Morrone
In complementary medicine, aromatherapy uses essential oils to improve agitation and aggression observed in dementia, mood, depression, anxiety and chronic pain. Preclinical research studies have reported that the essential oil obtained from bergamot (BEO) fruit (Citrus bergamia, Risso) modifies normal and pathological synaptic plasticity implicated, for instance, in nociceptive and neuropathic pain. Interestingly, recent results indicated that BEO modulates sensitive perception of pain in different models of nociceptive, inflammatory and neuropathic pain modulating endogenous systems...
2016: Mini Reviews in Medicinal Chemistry
https://www.readbyqxmd.com/read/26851838/the-effect-of-bergamot-on-dyslipidemia
#20
Rosaria Vincenza Giglio, Angelo Maria Patti, Dragana Nikolic, Giovanni Li Volti, Khalid Al-Rasadi, Niki Katsiki, Dimitri P Mikhailidis, Giuseppe Montalto, Ekaterina Ivanova, Alexander N Orekhov, Manfredi Rizzo
BACKGROUND: Statins are the most common used lipid lowering drugs but they may cause adverse effects and despite their well-established therapeutic benefits residual cardiovascular (CV) risk remains. The use of other lipid lowering drugs and nutraceuticals alone or as add-on lipid-modifying therapy can be an option in such cases. Several studies have reported health-related properties of the Citrus fruits, among which bergamot (Citrus bergamia Risso) differs from others by particularly high content of certain compounds...
October 15, 2016: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
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