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https://www.readbyqxmd.com/read/29664684/effect-of-breastfeeding-in-early-life-on-cardiorespiratory-and-physical-fitness-a-systematic-review-and-meta-analysis
#1
Javad Heshmati, Mahdi Sepidarkish, Farzad Shidfar, Fatemeh Shokri, Samira Vesali, Maryam Akbari, Reza Omani-Samani
BACKGROUND: Numerous studies have reported the associations between the type of feeding during infancy and subsequent chronic diseases. OBJECTIVE: The objective of this systematic review is to synthesize the available literature concerning the effect of breastfeeding in infancy on physical and cardiorespiratory fitness in children and adolescents. MATERIALS AND METHODS: We performed a comprehensive search of medical bibliographic databases to identify observational studies reporting the association between breastfeeding and cardiorespiratory or physical fitness...
April 17, 2018: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/29664667/food-security-and-its-related-factors-in-the-rural-households-of-bam-city-in-iran-a-logistic-regression-model-approach
#2
Saeed Khodabakhshzadeh, Samira Amirzadeh Moradabadi, Sadegh Khodabakhshzadeh, Mohammad Baniasadi, Touraj Harati Khalilabad
Awareness of the food security status of rural population and its influencing factors is essential for policy makers, public health institutions and the development of rural programs. This descriptive cross-sectional study was conducted in 2017 on 384 rural households in Bam city. The data was collected via the 6-item USDA questionnaire. Logistic regression was used to determine the relationship between social, economic and health factors with food security. The results indicate that 35.67% of households had full food security status, 24...
January 1, 2018: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/29659895/identification-of-differential-transcriptional-patterns-in-primary-and-secondary-hyperparathyroidism
#3
Samira M Sadowski, Marc Pusztaszeri, Marie-Claude Brulhart-Meynet, Volodymyr Petrenko, Claudio De Vito, Jonathan Sobel, Céline Delucinge-Vivier, Electron Kebebew, Romano Regazzi, Jacques Philippe, Frédéric Triponez, Charna Dibner
Context: Hyperparathyroidism is associated with hypercalcemia and the excess of parathyroid hormone secretion. However, the alterations in molecular pattern of functional genes during parathyroid tumorigenesis have not been unraveled. We aimed at establishing transcriptional patterns of normal and pathological parathyroid glands (PG) in sporadic primary and secondary hyperparathyroidism (HPT1, 2). Objective: To evaluate dynamic alterations in molecular patterns as a function of the type of PG pathology, a comparative transcript analysis was conducted in subgroups of healthy samples, sporadic HPT1 adenoma and hyperplasia, and HPT2...
April 5, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29658346/association-between-thrombophilia-gene-polymorphisms-and-recurrent-pregnancy-loss-risk-in-the-iranian-population
#4
Razieh Bigdeli, Mohammad Reza Younesi, Erfan Panahnejad, Vahid Asgary, Samaneh Heidarzadeh, Hoda Mazaheri, Samira Louni Aligoudarzi
Miscarriage is the most common complication in pregnancy. Considering the importance of the problem thrombophilia in pregnant women and its association with recurrent pregnancy loss (RPL), analysis of polymorphisms of genes involved in thrombophilia can be useful. We investigated the frequency and association between ten polymorphisms of seven thrombophilia genes and RPL in an Iranian population. This case-control study was conducted on 200 women with recurrent pregnancy loss and also on 200 women with at least one successful pregnancy as the control group...
April 15, 2018: Systems Biology in Reproductive Medicine
https://www.readbyqxmd.com/read/29653348/increased-oxidative-stress-in-the-mitochondria-isolated-from-lymphocytes-of-bipolar-disorder-patients-during-depressive-episodes
#5
Samira S Valvassori, Daniela V Bavaresco, Gustavo Feier, Kelen Cechinel-Recco, Amanda V Steckert, Roger B Varela, Cenita Borges, Milena Carvalho-Silva, Lara M Gomes, Emílio L Streck, João Quevedo
The present study aims to investigate the oxidative stress parameters in isolated mitochondria, as well as looking at mitochondrial complex activity in patients with Bipolar Disorder (BD) during depressive or euthymic episodes. This study evaluated the levels of mitochondrial complex (I, II, II-III and IV) activity in lymphocytes from BD patients. We evaluated the following oxidative stress parameters: superoxide, thiobarbituric acid reactive species (TBARS) and carbonyl levels in submitochondrial particles of lymphocytes from bipolar patients...
April 4, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29651440/mast-cell-the-neglected-member-of-the-tumor-microenvironment-role-in-breast-cancer
#6
REVIEW
Angélica Aponte-López, Ezequiel M Fuentes-Pananá, Daniel Cortes-Muñoz, Samira Muñoz-Cruz
Mast cells are unique tissue-resident immune cells that secrete a diverse array of biologically active compounds that can stimulate, modulate, or suppress the immune response. Although mounting evidence supports that mast cells are consistently infiltrating tumors, their role as either a driving or an opposite force for cancer progression is still controversial. Particularly, in breast cancer, their function is still under discussion. While some studies have shown a protective role, recent evidence indicates that mast cells enhance blood and lymphatic vessel formation...
2018: Journal of Immunology Research
https://www.readbyqxmd.com/read/29629987/markedly-deranged-injury-site-metabolism-and-impaired-functional-recovery-in-acute-spinal-cord-injury-patients-with-fever
#7
Mathew J Gallagher, Argyro Zoumprouli, Isaac Phang, Jan M Schwab, Marcel A Kopp, Thomas Liebscher, Marios C Papadopoulos, Samira Saadoun
OBJECTIVES: To characterize the effect of fever after acute, traumatic spinal cord injury on injury site metabolism and patient outcome. DESIGN: Longitudinal cohort study. In 44 patients (London cohort), we determined the effect of fever on intrathecal injury site metabolism by analyzing 1,767 hours of intraspinal pressure and 759 hours of microdialysis data. We also determined the effect of fever burden, computed for the first 2 weeks in hospital, on neurologic outcome...
April 6, 2018: Critical Care Medicine
https://www.readbyqxmd.com/read/29625556/targeted-next-generation-sequencing-with-an-extended-gene-panel-does-not-impact-variant-detection-in-mitochondrial-diseases
#8
Morgane Plutino, Annabelle Chaussenot, Cécile Rouzier, Samira Ait-El-Mkadem, Konstantina Fragaki, Véronique Paquis-Flucklinger, Sylvie Bannwarth
BACKGROUND: Since the advent of next generation sequencing (NGS), several studies have tried to evaluate the relevance of targeted gene panel sequencing and whole exome sequencing for molecular diagnosis of mitochondrial diseases. The comparison between these different strategies is extremely difficult. A recent study analysed a cohort of patients affected by a mitochondrial disease using a NGS approach based on a targeted gene panel including 132 genes. This strategy led to identify the causative mutations in 15...
April 7, 2018: BMC Medical Genetics
https://www.readbyqxmd.com/read/29621717/circulating-levels-of-perfluoroalkyl-substances-and-left-ventricular-geometry-of-the-heart-in-the-elderly
#9
Ingrid Mobacke, Lars Lind, Linda Dunder, Samira Salihovic, P Monica Lind
AIMS: Some persistent organic pollutants (POPs) such as hexachlorobenzene (HCB) and some polychlorinated biphenyls (PCBs) have been shown to interfere with myocardial function and geometry. We therefore investigated if also another group of POPs: per- and polyfluoroalkyl substances (PFASs) were associated with alterations in left ventricular geometry. METHODS: 801 subjects aged 70 years were investigated in a cross-sectional study within the scope of the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study...
April 2, 2018: Environment International
https://www.readbyqxmd.com/read/29621645/self-assembled-and-ph-sensitive-mixed-micelles-as-an-intracellular-doxorubicin-delivery-system
#10
Samira Jafarzadeh-Holagh, Sameereh Hashemi-Najafabadi, Hossein Shaki, Ebrahim Vasheghani-Farahani
Nanocarrier-based drug delivery systems have been explored extensively in cancer therapy. Among the vast number of different nanocarrier systems applied to deliver chemotherapeutics to cancer tumor, intelligent systems which deliver drug to various sites in the body have attracted considerable attentions. Finding a specific stimulant that triggers the carrier to release its payload in the target tissue is a key parameter for efficacy of delivery systems. Acidic pH of cancer tumor helps a pH-sensitive carrier to release drug at the tumor site...
March 1, 2018: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29621576/a-comparative-study-of-the-disinfection-efficacy-of-h-2-o-2-ferrate-and-uv-h-2-o-2-ferrate-processes-on-inactivation-of-bacillus-subtilis-spores-by-response-surface-methodology-for-modeling-and-optimization
#11
Atiyeh Rajabi Matin, Samira Yousefzadeh, Ehsan Ahmadi, Amirhossain Mahvi, Mahmood Alimohammadi, Hassan Aslani, Ramin Nabizadeh
Although chlorination can inactivate most of the microorganisms in water but protozoan parasites like C. parvum oocysts and Giardia cysts can resist against it. Therefore, many researches have been conducted to find a novel method for water disinfection. Present study evaluated the synergistic effect of H2O2 and ferrate followed by UV radiation to inactivate Bacillus subtilis spores as surrogate microorganisms. Response surface methodology(RSM) was employed for the optimization for UV/H2O2/ferrate and H2O2/ferrate processes...
April 2, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29620724/expanding-the-phenome-and-variome-of-skeletal-dysplasia
#12
Sateesh Maddirevula, Saud Alsahli, Lamees Alhabeeb, Nisha Patel, Fatema Alzahrani, Hanan E Shamseldin, Shams Anazi, Nour Ewida, Hessa S Alsaif, Jawahir Y Mohamed, Anas M Alazami, Niema Ibrahim, Firdous Abdulwahab, Mais Hashem, Mohamed Abouelhoda, Dorota Monies, Nada Al Tassan, Muneera Alshammari, Afaf Alsagheir, Mohammed Zain Seidahmed, Samira Sogati, Mona S Aglan, Muddathir H Hamad, Mustafa A Salih, Ahlam A Hamed, Nadia Alhashmi, Amira Nabil, Fatima Alfadli, Ghada M H Abdel-Salam, Hisham Alkuraya, Winnie Ong Peitee, W T Keng, Abdullah Qasem, Aziza M Mushiba, Maha S Zaki, Mahmoud R Fassad, Majid Alfadhel, Saji Alexander, Yasser Sabr, Samia Temtamy, Alka V Ekbote, Samira Ismail, Gamal Ahmed Hosny, Ghada A Otaify, Khalda Amr, Saeed Al Tala, Arif O Khan, Tamer Rizk, Aida Alaqeel, Abdulmonem Alsiddiky, Ankur Singh, Seema Kapoor, Amal Alhashem, Eissa Faqeih, Ranad Shaheen, Fowzan S Alkuraya
PurposeTo describe our experience with a large cohort (411 patients from 288 families) of various forms of skeletal dysplasia who were molecularly characterized.MethodsDetailed phenotyping and next-generation sequencing (panel and exome).ResultsOur analysis revealed 224 pathogenic/likely pathogenic variants (54 (24%) of which are novel) in 123 genes with established or tentative links to skeletal dysplasia. In addition, we propose 5 genes as candidate disease genes with suggestive biological links (WNT3A, SUCO, RIN1, DIP2C, and PAN2)...
April 5, 2018: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/29620696/mephenesin-is-there-a-progression-in-cases-of-substance-use-related-disorders-in-france
#13
Cecile Chevallier, Anne Batisse, Maeva Fortias, Samira Djezzar
No abstract text is available yet for this article.
April 3, 2018: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29618911/risk-assessment-of-workers-exposure-to-volatile-organic-compounds-in-the-air-of-a-petrochemical-complex-in-iran
#14
Farshid Ghorbani Shanh, Samira Rahimnejad, Abdulrahman Bahrami, Maryam Farhadian
Context: Long-term exposure to volatile organic compounds (VOCs) affects the occupancies health in petrochemical complex. Objectives: The aim of this study is to apply the lifetime cancer risk (LCR) and hazard quotient (HQ) in occupational exposure to estimate the risk of VOCs in petrochemical complexes. Settings and Design: A cross-sectional study was conducted in the petrochemical complex of Iran for a period of 1 year. Materials and Methods: Sorbent tubes were used to obtain air samples from 169 workers at different petrochemical complexes in southern Iran...
September 2017: Indian Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29617499/mortality-predictors-in-the-surgical-treatment-of-active-infective-endocarditis
#15
Jenny Lourdes Rivas de Oliveira, Magaly Arrais Dos Santos, Renato Tambellini Arnoni, Auristela Ramos, Dorival Della Togna, Samira Kaissar Ghorayeb, Roberto Tadeu Magro Kroll, Luiz Carlos Bento de Souza
INTRODUCTION: Active infective endocarditis is associated with high morbidity and mortality. Surgery is indicated in high-risk conditions, and the main determinants of mortality in surgical treatment should be evaluated. OBJECTIVE: To identify mortality predictors in the surgical treatment of active infective endocarditis in a long-term follow-up. METHODS: This prospective observational study involved 88 consecutive patients diagnosed with active infective endocarditis, who underwent surgery between January 2005 and December 2015...
January 2018: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29615897/adenosine-a-2a-receptors-control-glutamatergic-synaptic-plasticity-in-fast-spiking-interneurons-of-the-prefrontal-cortex
#16
Amber Kerkhofs, Paula M Canas, A J Timmerman, Tim S Heistek, Joana I Real, Carolina Xavier, Rodrigo A Cunha, Huibert D Mansvelder, Samira G Ferreira
Adenosine A2A receptors (A2A R) are activated upon increased synaptic activity to assist in the implementation of long-term plastic changes at synapses. While it is reported that A2A R are involved in the control of prefrontal cortex (PFC)-dependent behavior such as working memory, reversal learning and effort-based decision making, it is not known whether A2A R control glutamatergic synapse plasticity within the medial PFC (mPFC). To elucidate that, we tested whether A2A R blockade affects long-term plasticity (LTP) of excitatory post-synaptic potentials in pyramidal neurons and fast spiking (FS) interneurons in layer 5 of the mPFC and of population spikes...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29615068/modeling-and-rescue-of-defective-blood-brain-barrier-function-of-induced-brain-microvascular-endothelial-cells-from-childhood-cerebral-adrenoleukodystrophy-patients
#17
Catherine A A Lee, Hannah S Seo, Anibal G Armien, Frank S Bates, Jakub Tolar, Samira M Azarin
BACKGROUND: X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ABCD1 gene. 40% of X-ALD patients will convert to the deadly childhood cerebral form (ccALD) characterized by increased permeability of the brain endothelium that constitutes the blood-brain barrier (BBB). Mutation information and molecular markers investigated to date are not predictive of conversion. Prior reports have focused on toxic metabolic byproducts and reactive oxygen species as instigators of cerebral inflammation and subsequent immune cell invasion leading to BBB breakdown...
April 4, 2018: Fluids and Barriers of the CNS
https://www.readbyqxmd.com/read/29609192/the-burden-of-indirect-causes-of-maternal-morbidity-and-mortality-in-the-process-of-obstetric-transition-a-cross-sectional-multicenter-study
#18
Jessica Fernandes Cirelli, Fernanda Garanhani Surita, Maria Laura Costa, Mary Angela Parpinelli, Samira Maerrawi Haddad, José Guilherme Cecatti
OBJECTIVE:  The aim of this study is to evaluate the burden of indirect causes of maternal morbidity/mortality in Brazil. METHODS:  Secondary analysis of a multicenter cross-sectional study conducted in 27 referral obstetric units within the Brazilian Network for Surveillance of Severe Maternal Morbidity. RESULTS:  A total of 82,388 women were surveilled: 9,555 women with severe maternal morbidity were included, and 942 (9.9%) of them had indirect causes of morbidity/mortality...
March 2018: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/29608982/stochastic-exposure-and-health-risk-assessment-of-rice-contamination-to-the-heavy-metals-in-the-market-of-iranshahr-iran
#19
Babak Djahed, Mahmoud Taghavi, Mehdi Farzadkia, Samira Norzaee, Mohammad Miri
An investigation of some heavy metals content in rice (Oryza sativa) and associated health risks was carried out for residents of Iranshahr city, Iran. Average daily rice consumption of the citizens and most widely used rice brands in the market of Iranshahr were determined using a questionnaire. Besides, the concentration of heavy metals in the gathered rice samples was measured by inductively coupled plasma mass spectrometry (ICP-MS). Monte Carlo uncertainty simulation was utilized in conducting exposure assessment and investigating the non-carcinogenic effects of the studied elements as well as the carcinogenic effect of As...
March 30, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29606967/effects-of-oregano-essential-oil-on-brain-tlr4-and-tlr2-gene-expression-and-depressive-like-behavior-in-a-rat-model
#20
Azam Amiresmaeili, Samira Roohollahi, Ali Mostafavi, Nayere Askari
The aim of the present study was to evaluate the effects of oregano essential oil (OEO) on the hippocampus and prefrontal cortex TLR 2/4 gene expression and depressive like behavior induced by chronic unpredictable stress (CUS). Sucrose preference and forced swim tests were adopted to examine the antidepressant effect. Control (CON), OEO, CUS, and CUS + OEO groups were used. The OEO and CUS + OEO groups received OEO (0.2 mL/kg, i.p.), CON and CUS received saline (0.2 mL/kg, i.p.), and the positive drug groups of CUS rats received fluoxetine (10 mg/kg) and diazepam (3 mg/kg) once daily for 14 days...
April 2018: Research in Pharmaceutical Sciences
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