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https://www.readbyqxmd.com/read/29045301/cannabinoid-hyperemesis-syndrome-chs-a-parisian-case-series
#1
Maude Marillier, Anne Batisse, Yves Edel, An-Hung Nguyen, Cécile Chevallier, Grégory Pfau, Philippe Podevin, Samira Djezzar
No abstract text is available yet for this article.
October 17, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29043708/comparison-of-in-vitro-fertilization-intracytoplasmic-sperm-injection-cycle-outcome-in-patients-with-and-without-polycystic-ovary-syndrome-a-modified-poisson-regression-model
#2
Amir Almasi-Hashiani, Mohammad Ali Mansournia, Mahdi Sepidarkish, Samira Vesali, Azadeh Ghaheri, Arezoo Esmailzadeh, Reza Omani-Samani
Background: Polycystic ovary syndrome (PCOS) is a frequent condition in reproductive age women with a prevalence rate of 5-10%. This study intends to determine the relationship between PCOS and the outcome of assisted reproductive treatment (ART) in Tehran, Iran. MATERIALS AND METHODS: In this historical cohort study, we included 996 infertile women who referred to Royan Institute (Tehran, Iran) between January 2012 and December 2013. PCOS, as the main variable, and other potential confounder variables were gathered...
January 2018: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/29042457/neutralizing-antibody-mediated-response-and-risk-of-bk-virus-associated-nephropathy
#3
Morgane Solis, Aurélie Velay, Raphaël Porcher, Pilar Domingo-Calap, Eric Soulier, Mélanie Joly, Mariam Meddeb, Wallys Kack-Kack, Bruno Moulin, Siamak Bahram, Françoise Stoll-Keller, Heidi Barth, Sophie Caillard, Samira Fafi-Kremer
BK virus-associated nephropathy (BKVAN) causes renal allograft dysfunction. The current management of BKVAN relies on pre-emptive adaptation of immunosuppression according to viral load monitoring. However, this empiric strategy is not always successful. Therefore, pretransplant predictive markers are needed. In a prospective longitudinal study, we enrolled 168 kidney transplant recipients and 69 matched donors. To assess the value of BKV genotype-specific neutralizing antibody (NAb) titers as a predictive marker for BKV replication, we measured BKV DNA load and NAb titers at transplant and followed patients for 24 months...
October 17, 2017: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/29041704/optical-and-electrical-trade-offs-of-rib-to-contact-distance-in-depletion-type-ring-modulators
#4
Samira Karimelahi, Wahid Rahman, Mahdi Parvizi, Naim Ben-Hamida, Ali Sheikholeslami
We present a study on electrical and optical trade-offs of the doping map in a ring modulator. Here, we investigate the effects of the high-doped region distance to edge of the waveguide sidewall. Four groups of ring modulators with different rib-to-contact distances are fabricated and measured where the key parameters such as extinction ratio, insertion loss, transmission penalty, and bandwidth are compared quantitatively. Small-signal responses for the selected ring modulators are simulated where results are in agreement with measurement results...
August 21, 2017: Optics Express
https://www.readbyqxmd.com/read/29038743/mature-induced-pluripotent-stem-cell-derived-human-podocytes-reconstitute-kidney-glomerular-capillary-wall-function-on-a-chip
#5
Samira Musah, Akiko Mammoto, Thomas C Ferrante, Sauveur S F Jeanty, Mariko Hirano-Kobayashi, Tadanori Mammoto, Kristen Roberts, Seyoon Chung, Richard Novak, Miles Ingram, Tohid Fatanat-Didar, Sandeep Koshy, James C Weaver, George M Church, Donald E Ingber
An in vitro model of the human kidney glomerulus - the major site of blood filtration - could facilitate drug discovery and illuminate kidney-disease mechanisms. Microfluidic organ-on-a-chip technology has been used to model the human proximal tubule, yet a kidney-glomerulus-on-a-chip has not been possible because of the lack of functional human podocytes - the cells that regulate selective permeability in the glomerulus. Here, we demonstrate an efficient (> 90%) and chemically defined method for directing the differentiation of human induced pluripotent stem (hiPS) cells into podocytes that express markers of the mature phenotype (nephrin+, WT1+, podocin+, Pax2-) and that exhibit primary and secondary foot processes...
2017: Nature biomedical engineering
https://www.readbyqxmd.com/read/29037571/effect-of-ruta-chalepensis-on-zinc-lipid-profile-and-antioxidant-levels-in-the-blood-and-tissue-of-streptozotocin-induced-diabetes-in-rats-fed-zinc-deficient-diets
#6
Malika Hamdiken, Samira Bouhalit, Zine Kechrid
In diabetes, oxidative stress and lipid abnormalities are common and pronounced and represent important factors that are involved in the development of complications of diabetes. Zinc deficiency generally induces oxidative stress, but it is well known that the antioxidant Ruta chalepensis has an effective modulator role in oxidative stress in metabolic diseases. The aim of this study was to investigate the effect of R. chalepensis extract on blood biochemical parameters, tissue zinc status and antioxidant systems in rats with diabetes that were fed zinc-deficient diets...
October 13, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29033090/the-antimicrobial-peptide-ll-37-as-a-possible-adjunct-for-the-proliferation-and-differentiation-of-dental-pulp-stem-cells
#7
Noala Vicensoto Moreira Milhan, Patricia Pimentel de Barros, Elis Andrade de Lima Zutin, Felipe Eduardo de Oliveira, Carlos Henrique Ribeiro Camargo, Samira Esteves Afonso Camargo
INTRODUCTION: This study evaluated the biocompatibility of 5 and 10 μg/mL LL-37 in vitro and its effect on the differentiation of human dental pulp stem cells (DPSCs) into odontoblast-like cells. METHODS: Cell viability, genotoxicity, nitric oxide production, cell cycle, dentine sialophosphoprotein (DSPP) production, and DSPP gene expression. RESULTS: Concentrations of 5 and 10 μg/mL of LL-37 were not cytotoxic and generally increased cell viability, especially on the third day (P < ...
October 12, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/29031243/preparation-and-evaluation-of-rifampicin-and-co-trimoxazole-loaded-nanocarrier-against-brucella-melitensis-infection
#8
Narges Bodaghabadi, Samira Hajigholami, Ziba Vaise Malekshahi, Maliheh Entezari, Farhood Najafi, Hadi Shirzad, Majid Sadeghizadeh
Background: Brucellosis or Malta fever is a contagious infection common between human and domestic animals. Many antibiotics are used for brucellosis treatment, but they are not efficient and put heavy burden on society. Co-trimoxazole and rifampicin are two candidates for brucellosis treatment. In this study, we aimed to enhance the efficacy of these antibiotics using designed nanoparticles. Methods: Different concentrations of co-trimoxazole and rifampicin were used for loading onto a nanostructure of synthesized monomethoxy poly(ethylene glycol)-oleate (mPEG-OA)...
October 15, 2017: Iranian Biomedical Journal
https://www.readbyqxmd.com/read/29031151/fabrication-of-green-dye-sensitized-solar-cell-based-on-zno-nanoparticles-as-a-photoanode-and-graphene-quantum-dots-as-a-photo-sensitizer
#9
Golnoush Zamiri, Samira Bagheri
Zero-dimensional graphene quantum dots (GQDs) consist of single- or few-layer graphene with a size less than 20 nm and stand for a new type of QDs with unique properties combining the graphene nature and size-resulted quantum effects. GQDs possess unique optical and electronic properties, and in particular possess a band-gap less than 2.0 eV because of quantum confinement and edge effects. In this study, we investigated the performance of DSSCs using different thicknesses of ZnO nanoparticles as a photo-anode and GQDs as a green photosensitizer...
October 7, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29027470/next-generation-sequencing-applications-for-cardiovascular-disease
#10
Samira Kalayinia, Hamidreza Goodarzynejad, Majid Maleki, Nejat Mahdieh
The Human Genome Project (HGP), as the primary sequencing of the human genome, lasted more than one decade to be completed using the traditional Sanger's method. At present, next-generation sequencing (NGS) technology could provide the genome sequence data in hours. NGS has also decreased the expense of sequencing; therefore, nowadays it is possible to carry out both whole-genome (WGS) and whole-exome sequencing (WES) for the variations detection in patients with rare genetic diseases as well as complex disorders such as common cardiovascular diseases (CVDs)...
October 13, 2017: Annals of Medicine
https://www.readbyqxmd.com/read/29026645/synthesis-and-characterization-of-collagen-plga-biodegradable-skin-scaffold-fibers
#11
Alireza Sadeghi-Avalshahr, Samira Nokhasteh, Amir Mahdi Molavi, Mohammad Khorsand-Ghayeni, Meysam Mahdavi-Shahri
The aim of this study is to investigate the applicability of poly(lactic-co-glycolic acid) (PLGA)/collagen composite scaffold for skin tissue engineering. PLGA and collagen were dissolved in HFIP as a common solvent and fibrous scaffolds were prepared by electrospinning method. The scaffolds were characterized by scanning electron microscopy (SEM), FTIR spectroscopy, mercury porosimetry, tensile strength, biocompatibility assays and Biodegradation. Cytotoxicity and cell adhesion were tested for two cell line groups, human dermal fibroblast (HDF) and human keratinocyte (HaCat)...
October 2017: Regenerative Biomaterials
https://www.readbyqxmd.com/read/29025868/in-situ-visualization-of-glucocerebrosidase-in-human-skin-tissue-zymography-vs-activity-based-probe-labeling
#12
Jeroen van Smeden, Irini M Dijkhoff, Richard W J Helder, Hanin Al-Khakany, Daphne E C Boer, Anne Schreuder, Wouter W Kallemeijn, Samira Absalah, Herman S Overkleeft, Johannes M F G Aerts, Joke A Bouwstra
Epidermal glucocerebrosidase (GBA1), an acid β-glucosidase normally located in lysosomes, converts (glucosyl)ceramides into ceramides, which is crucial to generate an optimal barrier function of the outermost skin layer, the stratum corneum. Here we report on two developed in-situ methods to localize active GBA in human epidermis: i) an optimized zymography method that is less labour intensive and visualizes enzymatic activity with higher resolution than currently reported methods using either substrate 4-methylumbelliferyl-β-D-glucopyranoside or resorufin-β-D-glucopyranoside...
October 12, 2017: Journal of Lipid Research
https://www.readbyqxmd.com/read/29025150/collection-and-determinants-of-patient-reported-outcome-measures-in-haemodialysis-patients-in-scotland
#13
Ailish Nimmo, Samira Bell, Carol Brunton, Jacqueline Campbell, Arthur Doyle, Bruce MacKinnon, Robert K Peel, Susan Robertson, Ilona Shilliday, Elaine Spalding, Jamie P Traynor, Wendy Metcalfe
Background: Patient reported outcome measures (PROMs) can evaluate the quality of health in patients with established renal failure. There is limited experience of their use within national renal registries. Aim: To describe the Scottish Renal Registry's (SRR) experience of collecting PROMS in the haemodialysis population and correlate PROMS to demographic and clinical parameters. Design: Retrospective observational cross-sectional study. Methods: Haemodialysis patients in Scotland were invited to complete the KDQOL™-36 questionnaire on the day of the annual SRR census in 2015 and 2016...
September 18, 2017: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/29024129/efficacy-of-vitamins-e-and-c-for-reversing-the-cytotoxic-effects-of-nicotine-and-cotinine
#14
Maryam Torshabi, Zeinab Rezaei Esfahrood, Mahshid Jamshidi, Abbas Mansuri Torshizi, Samira Sotoudeh
Nicotine has adverse cellular and molecular effects on oral mucosa, bone, and teeth. Vitamin E (α-tocopherol) and vitamin C (ascorbic acid) are biological antioxidants with positive effects on wound healing and bone formation. This in vitro study sought to assess the cytotoxic effects of different concentrations of nicotine and cotinine (a metabolite of nicotine) on MG-63 osteoblast-like cells and human gingival fibroblasts (HGFs) in the presence and absence of antioxidant vitamins E and C (separately and combined)...
October 12, 2017: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29023747/cross-sectional-study-of-associations-between-prior%C3%A2-spontaneous-abortions-and-preterm-delivery
#15
Reza O Samani, Mohammad A Mansournia, Mahdi Sepidarkish, Amir Almasi-Hashiani, Saeid Safiri, Samira Vesali, Payam Amini, Saman Maroufizadeh
OBJECTIVE: To evaluate associations between a history of spontaneous abortion and preterm delivery during subsequent pregnancies. METHODS: The present secondary analysis included cross-sectional survey data related to all deliveries at 103 hospitals in Tehran, Iran, between July 6 and 21, 2015. Trained midwives interviewed patients within 24 hours of delivery. Adjusted odds ratios (ORs) with 95% confidence intervals (CIs) were calculated to investigate associations between spontaneous abortion and preterm delivery...
October 12, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29023479/evaluating-the-efficiency-of-chef-and-cmv-promoter-with-ires-and-furin-2a-linker-sequences-for-monoclonal-antibody-expression-in-cho-cells
#16
Saeedeh Ebadat, Samira Ahmadi, Maryam Ahmadi, Fatemeh Nematpour, Farzaneh Barkhordari, Reza Mahdian, Fatemeh Davami, Fereidoun Mahboudi
In recent years, monoclonal antibodies (mAbs) have been developed as powerful therapeutic and diagnostic agents and Chinese hamster ovary (CHO) cells have emerged as the dominant host for the recombinant expression of these proteins. A critical step in recombinant expression is the utilization of strong promoters, such as the Chinese Hamster Elongation Factor-1α (CHEF-1) promoter. To compare the strengths of CHEF with cytomegalovirus (CMV) promoter for mAb expression in CHO cells, four bicistronic vectors bearing either internal ribosome entry site (IRES) or Furin/2A (F2A) sequences were designed...
2017: PloS One
https://www.readbyqxmd.com/read/29023319/comparison-of-fenofibrate-and-pioglitazone-effects-on-patients-with-nonalcoholic-fatty-liver-disease
#17
Malek Yaghoubi, Sattar Jafari, Behnam Sajedi, Sepehr Gohari, Samira Akbarieh, Amir H Heydari, Maryam Jameshoorani
INTRODUCTION: Nonalcoholic fatty liver disease (NAFLD) is known to be a health-related problem; there is no proven treatment for NAFLD. However, a wide range of possible therapies have been proposed and studied. In the current study, we aimed to compare the therapeutic effects of fenofibrate and pioglitazone on NAFLD. PATIENTS AND METHODS: In this randomized clinical trial study (ethic number: ZUMS.REC.1393.133), patients with NAFLD and alanine aminotransferase in range of 1-1...
October 11, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29023073/reproductive-biology-of-sardinella-sp-sardinella-aurita-and-sardinella-maderensis-in-the-south-of-morocco
#18
Ayoub Baali, Hajar Bourassi, Samira Falah, Wahbi Abderrazik, Khalid Manchih, Khadija Amenzoui, Ahmed Yahyaoui
BACKGROUND AND OBJECTIVE: Sardinella sp. has gained much attention lately because of its biomass increase, which might be the result of climatic changes occurring across the Atlantic sea. Little information is known about reproduction of these species particularly in the Moroccan Atlantic area. The objective of the this study was to explore some aspects of the reproductive biology of Sardinella in the South of Atlantic Moroccan coast. MATERIALS AND METHODS: Monthly samples were collected during the period between February, 2015 and January, 2016 in the area between Cape Boujdor and Cape Blanc...
2017: Pakistan Journal of Biological Sciences: PJBS
https://www.readbyqxmd.com/read/29020306/lithium-and-tamoxifen-modulate-behavior-and-protein-kinase-c-activity-in-the-animal-model-of-mania-induced-by-ouabain-behavior-and-pkc-activity-in-animal-model
#19
Samira S Valvassori, Gustavo C Dal-Pont, Wilson R Resende, Roger B Varela, Bruna R Peterle, Fernanda F Gava, Franciele G Mina, José H Cararo, André F Carvalho, João Quevedo
Background: The intracerebroventricular (ICV) injection of ouabain, a specific inhibitor of the Na+/K+-adenosine-triphosphatase (Na+/K+-ATPase) enzyme, induces hyperactivity in rats in a putative animal model of mania. Several evidences have suggested that protein kinase C (PKC) signaling pathway is involved in bipolar disorder (BD). In addition, it is known that protein kinase C (PKC) inhibitors, such as lithium (Li) and tamoxifen (TMX), are effective in treating acute mania. Methods: In the present study, we investigated the effects of Li and TMX on PKC signaling pathway in the frontal cortex and hippocampus of rats submitted to the animal model of mania induced by ouabain...
August 7, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29018578/the-care-of-adolescents-and-young-adults-with-cancer-results-of-the-esmo-siope-survey
#20
Emmanouil Saloustros, Daniel P Stark, Kyriaki Michailidou, Giannis Mountzios, Laurence Brugieres, Fedro Alessandro Peccatori, Svetlana Jezdic, Samira Essiaf, Jean-Yves Douillard, Stefan Bielack
INTRODUCTION: Adolescents and young adults (AYA) with cancer require dedicated clinical management and care. Little is known about the training and practice of European healthcare providers in regard to AYA and the availability of specialised services. METHODS: A link to an online survey was sent to members of the European Society for Medical Oncology (ESMO) and the European Society for Paediatric Oncology (SIOPE). The link was also sent to ESMO National Representatives and circulated to other European oncology groups...
2017: ESMO Open
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