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Fatiha Mekircha, Samira Chebab, Rosita Gabbianelli, Essaid Leghouchi
This study aimed to verify whether Olea europaea L. (olive) oil (OEO) exerted a protective effect against oxidative stress induced by deltamethrin (DM) and alterations of pituitary, thyroid and gonadal hormones in adult female rats. DM (0,00256 g/kg body weight),OEO (0,6 g/kg body weight) and DM with OEO were administered to rats orally for 28 days. Volatile compounds present in olive oil were analysed by GC-MS. Estradiol (E2 ), Thyroxine (T4),Thyroid Stimulating Hormone (TSH), Triiodothyronine (T3), Follicle Stimulating Hormone (FSH), Luteinizing Hormone (LH), Progesterone (Pg) were measured in serum using Chemiluminescent Microparticle Immunoassay (CMIA)...
June 11, 2018: Ecotoxicology and Environmental Safety
Seyed Mohammad Nabavi, Seyed Fazel Nabavi, Antoni Sureda, Janbo Xiao, Ahmad Reza Dehpour, Samira Shirooie, Ana Sanches Silva, Alessandra Baldi, Haroon Khan, Maria Daglia
N-acetyl-5-methoxy-tryptamine (melatonin) is a natural substance produced both by plants, as a secondary metabolite, and animals, by the pineal gland and other tissues. In humans, melatonin participates in numerous functions including the regulation of mood, sleep, reproduction, promotion of immunomodulation, antioxidant defense and as an anti-inflammatory agent. The anti-inflammatory activity of melatonin could yield beneficial effects on intake, particularly against the chronic inflammation which underlies many chronic diseases...
June 14, 2018: Critical Reviews in Food Science and Nutrition
Mehdi Qasemi, Mojtaba Afsharnia, Ahmad Zarei, Ali Asghar Najafpoor, Samira Salari, Mahmoud Shams
Phenol is a hazardous organic chemical that introduced into the environment by industrial and pharmaceutical discharges. As a versatile option for phenol removal, adsorption would be viable if it accompanying with low cost adsorbents. This article described a natural, very cheap and local available adsorbent for phenol removal. Phenol showed a high affinity to Citrullus colocynthis waste ash which mainly composed of SiO2 (41.6%), Al2 O3 (17.3%) and MgO (15.9%). Up to 70% of phenol adsorbed in the first 30 min of agitation...
June 2018: Data in Brief
Izadora Nogueira Fonte Boa, Carolina de Medeiros Rimkus, Kenia Repiso Campanholo, Samira Luisa Apóstolos Pereira, Thiago de Faria Junqueira, Melissa de Almeida Rodrigues Machado, Dagoberto Callegaro, Maria Concepción García Otaduy, Claudia da Costa Leite, Eliane Correa Miotto
OBJECTIVE: A 4.5-year follow-up study was conducted to characterize baseline verbal episodic memory (VEM) and its behavior and to assess the effects of relapsing-remitting multiple sclerosis (RRMS) on this domain. METHODS: Twenty-nine patients with RRMS underwent two neuropsychological assessments performed an average of 4.5 years apart. Twenty-six control participants underwent a single neuropsychological assessment. A significance level of p < 0.005 was adopted to denote a significant difference between the groups on the Mann Whitney and Wilcoxon paired statistical analyses...
May 2018: Arquivos de Neuro-psiquiatria
Phillip E McClean, Kirstin E Bett, Robert Stonehouse, Rian Lee, Stephanie Pflieger, Samira Mafi Moghaddam, Valerie Geffroy, Phil Miklas, Sujan Mamidi
The presence of seed color in common bean (Phaseolus vulgaris) requires the dominant-acting P (pigment) gene, and white seed is a recessive phenotype in all domesticated races of the species. P was classically associated with seed size, thus describing it as the first genetic marker for a quantitative trait. The molecular structure of P was characterized to understand the selection of white seeds during bean diversification and the relationship of P to seed weight. P was identified by homology searches, a genome-wide association study (GWAS) and gene remodeling, and confirmed by gene silencing...
June 13, 2018: New Phytologist
Samira Kashinath Dhamapurkar, Barbara A Wilson, Anita Rose, Gerhard Florschutz, Peter Watson, Agnes Shiel
BACKGROUND & OBJECTIVE: Patients with brain injury are at high risk for infections. Although infection and cognitive deterioration are established for people with dementia, this has not been shown for patients with a prolonged disorder of consciousness (PDOC). This study determines whether regular Wessex Head Injury Matrix (WHIM) assessments can identify early signs of infections in patients with PDOC. METHOD: Retrospective and prospective approaches were used to assess the WHIM scores of patients with a PDOC (N = 21 in the retrospective study and 22 in the prospective study)...
June 12, 2018: Brain Injury: [BI]
Zhao Cai, Daojin Zhou, Maoyu Wang, Seongmin Bak, Yueshen Wu, Zishan Wu, Yang Tian, Xuya Xiong, Yaping Li, Wen Liu, Samira Siahrostami, Yun Kuang, Xiao-Qing Yang, Haohong Duan, Zhenxing Feng, Hailiang Wang, Xiaoming Sun
Exploring materials with regulated local structures and understanding how the atomic motifs govern the reactivity and durability of catalysts are a critical challenge for designing advanced catalysts. Here we report the tuning of the local atomic structure of nickel-iron layered double hydroxides (NiFe-LDHs) by partially substituting Ni2+ with Fe2+ to introduce Fe-O-Fe moieties. These Fe2+-containing NiFe-LDHs exhibit enhanced oxygen evolution reaction (OER) activity with an ultralow overpotential of 195 mV at the current density of 10 mA/cm2, which is among the best OER catalytic performance reported to date...
June 11, 2018: Angewandte Chemie
Noushin Shabani, Javad Razaviyan, Mahdi Paryan, Seyed Mohammad Tavangar, Fereidoun Azizi, Samira Mohammadi-Yeganeh, Mehdi Hedayati
Medullary Thyroid Carcinoma (MTC) is a rare neoplasia derived from neural parafollicular C cells. MicroRNAs (miRNAs) are small regulatory RNAs with essential roles in the biology of cancers such as MTC and can be applied as diagnostic markers. According to previous studies, miR-144 and miR-34 and their two oncogenes target, mammalian target of rapamycin (mTOR) and AXL receptor tyrosine kinase (AXL), were selected for further investigations in our study. Thirty MTC samples as well as thirty adjacent normal thyroid tissues were applied in this study including 28 Formalin-Fixed Paraffin-Embedded (FFPE) and 2 fresh-frozen MTC samples...
June 6, 2018: Human Pathology
Aaron Campigotto, Andrew E Simor, Allison McGeer, Alexander Kiss, Samira Mubareka
Nasopharyngeal swabs from 148 adult patients with influenza were analyzed by polymerase chain reaction for Staphylococcus aureus and or Streptococcus pneumoniae. We found that patients colonized with S. pneumoniae were younger, had lower oxygen saturations, and were more likely to require admission to critical care.
June 5, 2018: Diagnostic Microbiology and Infectious Disease
Titilayo Tatiana Agbadjé, Matthew Menear, Michèle Dugas, Marie-Pierre Gagnon, Samira Abbasgholizadeh Rahimi, Hubert Robitaille, Anik M C Giguère, François Rousseau, Brenda J Wilson, France Légaré
BACKGROUND: For pregnant women and their partners, the decision to undergo Down syndrome prenatal screening is difficult. Patient decision aids (PtDA) can help them make an informed decision. We aimed to identify behaviour change techniques (BCTs) that would be useful in an intervention to promote the use of a PtDA for Down syndrome prenatal screening, and to identify which of these BCTs pregnant women found relevant and acceptable. METHODS: Using the Behaviour Change Wheel and the Theoretical Domains Framework, we conducted a qualitative descriptive study...
June 8, 2018: BMC Health Services Research
Rozalynne Samira, Baohua Li, Daniel Kliebenstein, Chunying Li, Eric Davis, Jeffrey W Gillikin, Terri A Long
ILR3 and PYE function in a regulatory network that modulates GLS accumulation under iron deficiency. The molecular processes involved in the cross talk between iron (Fe) homeostasis and other metabolic processes in plants are poorly understood. In Arabidopsis thaliana the transcription factor IAA-LEUCINE RESISTANT3 (ILR3) regulates iron deficiency response, aliphatic glucosinolate (GLS) biosynthesis and pathogen response. ILR3 is also known to interact with its homolog, POPEYE (PYE), which also plays a role in Fe response...
June 7, 2018: Plant Molecular Biology
Samira Dodangeh, Maryam Niyyati, Mohammad Kamalinejad, Jacob Lorenzo-Morales, Abdolali Moshfe, Ali Haghighi, Eznolah Azargashb
Acanthamoeba keratitis (AK) is a sight-threatening infection of the cornea disease that often presents with a lengthy and not fully effective treatment. Current therapeutic options against Acanthamoeba are not very effective against the cyst. Calibrated trophozoite/cyst suspension was incubated with the same volume of serial dilutions of the Trigonella foenum graecum aqueous extract (200, 250, 350, 450, 600, and 750 mg/mL) in microcentrifuge tubes and mixed by pipetting up and down. After that, the tubes were incubated at 26 ºC for 24, 48, and 72 h...
2018: Iranian Journal of Pharmaceutical Research: IJPR
Mohammad Heidary, Samira Alesaeidi, Khashayar Afshari
Neurological manifestations are reported as a consequence of primary Sjӧgren syndrome (PSS). Any part of the brain and peripheral nervous system can be involved in PSS. However, cerebellar degeneration and atrophy associated with PSS have been rarely reported. Our report describes a 22-year-old woman who presented with cerebellar ataxia, arthritis and arthralgia. Evaluation of her symptoms, autoantibodies and salivary gland pathology was in favour of the diagnosis of Sjögren syndrome. Also, her brain MRI revealed cerebellar degeneration...
June 6, 2018: BMJ Case Reports
Sholeh Hamzehzadeh, Samira Touri
The potential of {polyethylene glycol 400 + potassium citrate} aqueous biphasic system (ABS) with ionic liquid (IL) 1-butyl-3-methylimidazolium bromide ([C4 C1 im]Br) as an adjuvant is examined for the extraction of L-phenylalanine (Phe), as a model biomolecule, at different temperatures and system compositions. The binodal curves and liquid-liquid equilibrium data were determined by the addition of 5 wt% IL to investigate its effect on phase diagrams and Phe partition coefficients. The results indicate that binodal curves of systems with and without IL are more deviated from each other with decreasing temperature...
June 7, 2018: Biotechnology Progress
Lucas A Shaw, Samira Chizari, Maxim Shusteff, Hamed Naghsh-Nilchi, Dino Di Carlo, Jonathan B Hopkins
An error in a reference is reported and corrected.
May 28, 2018: Optics Express
Asmâa Biaz, Mohammed Drissi, Aissam El Maataoui, Samira El Machtani Idrissi, Sanae Bouhsain, Abdellah Dami, Abdellatif Boulahya, Zohra Ouzzif
Introduction: This prospective study was conducted at the Laboratoy of Biochemistry of the HMIMV, Rabat, over a period of 1 year. It aimed to analyse the kinetics of troponin lc (cTnl) after on-pump cardiac surgery in order to establish threshold values for the diagnosis of perioperative myocardial infarction. Methods: The study included 58 patients who had undergone on-pump valvular surgery or on-pump coronary artery bypass surgery. These patients were separated into 3 groups according to their clinical and electrical evolution as well as their laboratory tests (cTnI) during the immediate post-operative period...
2018: Pan African Medical Journal
Christoph Nowak, Susanne Hetty, Samira Salihovic, Casimiro Castillejo-Lopez, Andrea Ganna, Naomi L Cook, Corey D Broeckling, Jessica E Prenni, Xia Shen, Vilmantas Giedraitis, Johan Ärnlöv, Lars Lind, Christian Berne, Johan Sundström, Tove Fall, Erik Ingelsson
Insulin resistance (IR) predisposes to type 2 diabetes and cardiovascular disease but its causes are incompletely understood. Metabolic challenges like the oral glucose tolerance test (OGTT) can reveal pathogenic mechanisms. We aimed to discover associations of IR with metabolite trajectories during OGTT. In 470 non-diabetic men (age 70.6 ± 0.6 years), plasma samples obtained at 0, 30 and 120 minutes during an OGTT were analyzed by untargeted liquid chromatography-mass spectrometry metabolomics. IR was assessed with the hyperinsulinemic-euglycemic clamp method...
June 6, 2018: Scientific Reports
Sarah Moeschler, Samira Locher, Gert Zimmer
Cellular kinases are crucial for the transcription/replication of many negative-strand RNA viruses and might serve as targets for antiviral therapy. In this study, a library comprising 80 kinase inhibitors was screened for antiviral activity against vesicular stomatitis virus (VSV), a prototype member of the family Rhabdoviridae . 1-Benzyl-3-cetyl-2-methylimidazolium iodide (NH125), an inhibitor of eukaryotic elongation factor 2 (eEF2) kinase, significantly inhibited entry of single-cycle VSV encoding a luciferase reporter...
June 5, 2018: Viruses
Shucheng Chen, Zhihua Chen, Samira Siahrostami, Drew Higgins, Dennis Nordlund, Dimosthenis Sokaras, Taeho Roy Kim, Yunzhi Liu, Xuzhou Yan, Elisabeth Nilsson, Robert Sinclair, Jens K Norskov, Thomas F Jaramillo, Zhenan Bao
Heteroatom-doped carbons have drawn increasing research interest as catalysts for various electrochemical reactions due to their unique electronic and surface structures. In particular, co-doping of carbon with boron and nitrogen has been shown to provide significant catalytic activity for oxygen reduction reactions (ORR). However, limited experimental work has been done to systematically study these materials and much remains to be understood about the nature of the active site(s) and the factors under-lying the activity enhancements of these boron, carbon and nitrogen (BCN) materials...
June 6, 2018: Journal of the American Chemical Society
Samira Jeimy, Jenny Yujing Wang, Lisa Richardson
OBJECTIVE: The virtual patient (VP) is a computer program that simulates real-life clinical scenarios and allows learners to make diagnostic and therapeutic decisions in a safe environment. Although many VP cases are available, few focus on junior trainees as their target audience. In addition, there is wide variability in trainees' clinical rotation experiences, based on local practice and referral patterns, duty hour restrictions, and competing educational requirements. In order to standardize clinical exposure and improve trainees' knowledge and perceived preparedness to manage core internal medicine cases, we developed a pool of VP cases to simulate common internal medicine presentations...
June 5, 2018: BMC Research Notes
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