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Abdominal components separation

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https://www.readbyqxmd.com/read/28087488/cathepsin-k-targeted-sub-micron-particles-for-regenerative-repair-of-vascular-elastic-matrix
#1
Brenton Jennewine, Jonathan Fox, Anand Ramamurthi
: Abdominal Aortic Aneurysms (AAA) involve slow dilation and weakening of the aortic wall due to breakdown of structural matrix components, such as elastic fibers by chronically overexpressed matrix metalloproteinases (MMPs), primarily, MMPs-2 and -9. Auto-regenerative repair of disrupted elastic fibers by smooth muscle cells (SMCs) at the AAA site is intrinsically poor and together with chronic proteolysis prevents restoration of elastin homeostasis, necessary to enable AAA growth arrest or regression to a healthy state...
January 10, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28046024/chest-fat-quantification-via-ct-based-on-standardized-anatomy-space-in-adult-lung-transplant-candidates
#2
Yubing Tong, Jayaram K Udupa, Drew A Torigian, Dewey Odhner, Caiyun Wu, Gargi Pednekar, Scott Palmer, Anna Rozenshtein, Melissa A Shirk, John D Newell, Mary Porteous, Joshua M Diamond, Jason D Christie, David J Lederer
PURPOSE: Overweight and underweight conditions are considered relative contraindications to lung transplantation due to their association with excess mortality. Yet, recent work suggests that body mass index (BMI) does not accurately reflect adipose tissue mass in adults with advanced lung diseases. Alternative and more accurate measures of adiposity are needed. Chest fat estimation by routine computed tomography (CT) imaging may therefore be important for identifying high-risk lung transplant candidates...
2017: PloS One
https://www.readbyqxmd.com/read/28044960/transversus-abdominis-muscle-release-tar-for-large-incisional-hernia-repair
#3
Valentin Oprea, Victor Gheorghe Radu, Doru Moga
: Background: complex ventral hernia repair is a frequent and challenging topic. Reconstructive techniques are numerous but most of them are unable to achieve the goals of hernioplasty. Posterior component separation with transverses abdominis muscle release (TAR) is a novel approach that offers a solution for complex ventral hernias. METHOD: The posterior rectus sheath is incised and the retrorectus plane is developed. In a modification of the Rives-Stoppa technique, the transversus abdominis is released medial to the linea semilunaris to expose a broad plane that extends from the central tendon of the diaphragm superiorly, to the space of Retzius inferiorly, and laterally to the retro-peritoneum...
November 2016: Chirurgia
https://www.readbyqxmd.com/read/28039640/hands-on-2-0-improving-transfer-of-training-via-the-society-of-american-gastrointestinal-and-endoscopic-surgeons-sages-acquisition-of-data-for-outcomes-and-procedure-transfer-adopt-program
#4
Jonathan Dort, Amber Trickey, John Paige, Erin Schwarz, Brian Dunkin
BACKGROUND: Practicing surgeons commonly learn new procedures and techniques by attending a "hands-on" course, though trainings are often ineffective at promoting subsequent procedure adoption in practice. We describe implementation of a new program with the SAGES All Things Hernia Hands-On Course, Acquisition of Data for Outcomes and Procedure Transfer (ADOPT), which employs standardized, proven teaching techniques, and 1-year mentorship. Attendee confidence and procedure adoption are compared between standard and ADOPT programs...
December 30, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27993696/long-term-outcomes-after-abdominal-wall-reconstruction-with-acellular-dermal-matrix
#5
Patrick B Garvey, Salvatore A Giordano, Donald P Baumann, Jun Liu, Charles E Butler
BACKGROUND: Long-term outcomes data for hernia recurrence rates following abdominal wall reconstruction (AWR) with acellular dermal matrix (ADM) are lacking. The aim of this study was to assess the long-term durability of AWR using ADM. STUDY DESIGN: We studied patients who underwent AWR with ADM at a single center in 2005-2015 with a minimum follow-up of 36 months. Hernia recurrence was the primary outcome and surgical site occurrence (SSO) was a secondary outcome...
December 16, 2016: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/27864458/three-dimensional-analysis-of-component-stability-of-the-nellix-endovascular-aneurysm-sealing-system-after-treatment-of-infrarenal-abdominal-aortic-aneurysms
#6
Bernhard Dorweiler, Christian Boedecker, Friedrich Dünschede, Christian F Vahl, Marwan Youssef
PURPOSE: To assess short-term stability and conformational changes of the Nellix EndoVascular Aneurysm Sealing (EVAS) System using 3-dimensional (3D) analysis. METHODS: Postoperative computed tomography (CT) scans obtained at 0, 3, and 12 months in 24 patients (mean age 75±7 years; 22 men) who underwent EVAS between December 2013 and December 2014 for intact abdominal aortic aneurysm (within the instructions for use) were evaluated for stent-graft deviation in multiple planes using dedicated 3D analysis software...
November 17, 2016: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/27804212/international-estimated-fetal-weight-standards-of-the-intergrowth-21-st-project
#7
J Stirnemann, J Villar, L J Salomon, E Ohuma, P Ruyan, D G Altman, F Nosten, R Craik, S Munim, L Cheikh Ismail, F C Barros, A Lambert, S Norris, M Carvalho, Y A Jaffer, J A Noble, E Bertino, M G Gravett, M Purwar, C Victora, R Uauy, Z Bhutta, S Kennedy, A T Papageorghiou
BACKGROUND: Estimated fetal weight (EFW) and fetal biometry are complementary measures to screen for fetal growth disturbances. Our aim was to provide international EFW standards to complement the INTERGROWTH-21(st) Fetal Growth Standards that are available for use worldwide. METHODS: Women with an accurate gestational age assessment, who were enrolled in the prospective, international, multicentre, population-based, Fetal Growth Longitudinal Growth Study (FGLS) and INTERBIO-21(st) Fetal Study (FS), two of the components of the INTERGROWTH-21(st) Project, had ultrasound scans every 5 weeks from 9-14 weeks until 40 weeks' gestation...
November 2, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27764968/the-relationship-between-anthropometry-and-body-composition-from-computed-tomography-the-mediators-of-atherosclerosis-in-south-asians-living-in-america-study
#8
Morgana Mongraw-Chaffin, Alka M Kanaya, Namratha R Kandula, Arti Shah, Cheryl A M Anderson
OBJECTIVE: Few studies examine the relationships between anthropometry and the body composition measures they approximate, or whether they differ by sex, and no studies have examined these relationships in South Asians living in the US. DESIGN: We conducted a cross-sectional study of 871 participants in the Mediators of Atherosclerosis in South Asians Living in America (MASALA) Study who had BMI < 40 kg/m(2) and underwent abdominal CT scans for measurement of visceral and subcutaneous fat...
October 21, 2016: Ethnicity & Health
https://www.readbyqxmd.com/read/27757337/abdominal-closure-after-tram-flap-breast-reconstruction-with-transversus-abdominis-muscle-release-and-mesh
#9
Antonio Espinosa-de-Los-Monteros, Héctor Avendano-Peza, Yuri W Novitsky
Breast reconstruction with a pedicled transverse rectus abdominis muscle (TRAM) flap can result in significant abdominal wall donor-site morbidity. Although the pedicled TRAM flap donor area reinforced with mesh results in decreased rates of postoperative abdominal bulging and hernias, the best technique to accomplish that is yet to be elucidated. We present our novel technique of posterior components separation with transversus abdominis muscle release and retromuscular mesh reinforcement for donor-area closure during pedicled TRAM flap breast reconstruction...
September 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/27753991/ed-05-3-association-between-persistent-organic-pollutants-and-metabolic-syndrome
#10
Duk Hee Lee
Metabolic syndrome (MetS) is a cluster of major cardiovascular risk factors like glucose intolerance, dyslipidemia, and high blood pressure. The most important risk factor for MetS is abdominal obesity. Also, insulin resistance is considered as an underlying pathophysiology of MetS. Under the current paradigm, excess calorie intake and physical inactivity are major contributors to obesity and insulin resistance.Meanwhile, many environmental chemicals have recently received attention as a significant contributor to obesity and obesity-related metabolic dysfunction...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27728955/laparoscopic-stapled-sublay-repair-with-self-gripping-mesh-a-simplified-technique-for-minimally-invasive-extraperitoneal-ventral-hernia-repair
#11
Alexandra M Moore, Lisa N Anderson, David C Chen
INTRODUCTION: Minimally invasive laparoscopic and robotic techniques for ventral hernia repair have evolved to achieve the benefits and minimize the limitations of both the open Rives-Stoppa sublay mesh repair and laparoscopic intraperitoneal onlay mesh (IPOM) repair. By combining the principles of a retromuscular repair with the benefits of a minimally invasive approach, these techniques attempt to decrease recurrence, increase functionality, exclude mesh from the viscera, limit infection and wound complications, and minimize pain...
October 26, 2016: Surgical Technology International
https://www.readbyqxmd.com/read/27696169/prior-radiotherapy-does-not-affect-abdominal-wall-reconstruction-outcomes-evidence-from-propensity-score-analysis
#12
Salvatore Giordano, Patrick B Garvey, Donald P Baumann, Jun Liu, Charles E Butler
BACKGROUND: Prior abdominal wall radiotherapy (XRT) adversely affects wound healing, but data are limited on how prior XRT may affect abdominal wall reconstruction (AWR) outcomes. The purpose of this study was to determine whether prior abdominal wall radiotherapy is associated with a higher incidence of complications following AWR for a hernia or oncologic resection defect. METHODS: We performed a retrospective study of consecutive patients who underwent complex AWR using acellular dermal matrix (ADM) at a single center...
September 30, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27658893/the-six-obesity-indices-which-one-is-more-compatible-with-metabolic-syndrome-a-population-based-study
#13
Nima Motamed, Masoudreza Sohrabi, Hossein Poustchi, Mansooreh Maadi, Mojtaba Malek, Hossein Keyvani, Mahboobeh Safaean Amoli, Farhad Zamani
OBJECTIVES: The present study was conducted to determine the best discriminators in the diagnosis of the metabolic syndrome (MetS) among six obesity indexes. Furthermore the optimal cutoff points for all obesity indexes were determined. METHODS: The baseline data of 5910 subjects of Haraz cohort study which was conducted in northern Iran were analyzed. Receiver operating characteristic (ROC) analyses were separately performed to determine discriminatory power of six obesity indexes, including, body mass index (BMI), waist circumference (WC), waist to hip ratio (WHR), waist to height ratio (WHtR), abdominal volume index (AVI) and conicity index (CI) for diagnosis of at least two other components of MetS...
August 23, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/27642902/ed-05-3-association-between-persistent-organic-pollutants-and-metabolic-syndrome
#14
Duk Hee Lee
Metabolic syndrome (MetS) is a cluster of major cardiovascular risk factors like glucose intolerance, dyslipidemia, and high blood pressure. The most important risk factor for MetS is abdominal obesity. Also, insulin resistance is considered as an underlying pathophysiology of MetS. Under the current paradigm, excess calorie intake and physical inactivity are major contributors to obesity and insulin resistance.Meanwhile, many environmental chemicals have recently received attention as a significant contributor to obesity and obesity-related metabolic dysfunction...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27565062/long-term-outcomes-of-sandwich-ventral-hernia-repair-paired-with-hybrid-vacuum-assisted-closure
#15
Caitlin W Hicks, Katherine E Poruk, Pablo A Baltodano, Kevin C Soares, Said C Azoury, Carisa M Cooney, Peter Cornell, Frederic E Eckhauser
BACKGROUND: Sandwich ventral hernia repair (SVHR) may reduce ventral hernia recurrence rates, although with an increased risk of surgical site occurrences (SSOs) and surgical site infections (SSIs). Previously, we found that a modified negative pressure wound therapy (hybrid vacuum-assisted closure [HVAC]) system reduced SSOs and SSIs after ventral hernia repair. We aimed to describe our outcomes after SVHR paired with HVAC closure. METHODS: We conducted a 4-y retrospective review of all complex SVHRs (biologic mesh underlay and synthetic mesh overlay) with HVAC closure performed at our institution by a single surgeon...
August 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/27551925/international-consensus-conference-on-open-abdomen-in-trauma
#16
REVIEW
Osvaldo Chiara, Stefania Cimbanassi, Walter Biffl, Ari Leppaniemi, Sharon Henry, Thomas M Scalea, Fausto Catena, Luca Ansaloni, Arturo Chieregato, Elvio de Blasio, Giorgio Gambale, Giovanni Gordini, Guiseppe Nardi, Pietro Paldalino, Francesco Gossetti, Paolo Dionigi, Giuseppe Noschese, Gregorio Tugnoli, Sergio Ribaldi, Sebastian Sgardello, Stefano Magnone, Stefano Rausei, Anna Mariani, Francesca Mengoli, Salomone di Saverio, Maurizio Castriconi, Federico Coccolini, Joseph Negreanu, Salvatore Razzi, Carlo Coniglio, Francesco Morelli, Maurizio Buonanno, Monica Lippi, Liliana Trotta, Annalisa Volpi, Luca Fattori, Mauro Zago, Paolo de Rai, Fabrizio Sammartano, Roberto Manfredi, Emiliano Cingolani
BACKGROUND: A part of damage-control laparotomy is to leave the fascial edges and the skin open to avoid abdominal compartment syndrome and allow further explorations. This condition, known as open abdomen (OA), although effective, is associated with severe complications. Our aim was to develop evidence-based recommendations to define indications for OA, techniques for temporary abdominal closure, management of enteric fistulas, and methods of definitive wall closure. METHODS: The literature from 1990 to 2014 was systematically screened according to PRISMA [Preferred Reporting Items for Systematic Reviews and Meta-analyses] protocol...
January 2016: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/27536495/extensive-abdominal-wall-incisional-heterotopic-ossification-reconstructed-with-component-separation-and-strattice-inlay
#17
Nergis Nina Suleiman, Lars Johan Marcus Sandberg
Symptomatic heterotopic ossification of abdominal surgical incisions is a rare occurrence. We present a 67-year-old man with severe discomfort caused by heterotopic ossification extending from the xiphoid to the umbilicus. The patient underwent an abdominal aortic aneurysm repair 3 years before our treatment. A 13 × 3.5 cm ossified lesion was excised. The resulting midline defect was closed using component separation and inlay Strattice. Tension-free midline adaptation of the recti muscles was achieved...
July 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/27528695/greater-success-of-primary-fascial-closure-of-the-open-abdomen-a-retrospective-study-analyzing-applied-surgical-techniques-success-of-fascial-closure-and-variables-affecting-the-results
#18
M Kääriäinen, M Kuuskeri, M Helminen, H Kuokkanen
BACKGROUND AND AIMS: The open abdomen technique is a standard procedure in the treatment of intra-abdominal catastrophe. Achieving primary abdominal closure within the initial hospitalization is a main objective. This study aimed to analyze the success of closure rate and the effect of negative pressure wound therapy, mesh-mediated medial traction, and component separation on the results. We present the treatment algorithm used in our institution in open abdomen situations based on these findings...
August 15, 2016: Scandinavian Journal of Surgery: SJS
https://www.readbyqxmd.com/read/27513800/initial-uk-experience-with-transversus-abdominis-muscle-release-for-posterior-components-separation-in-abdominal-wall-reconstruction-of-large-or-complex-ventral-hernias-a-combined-approach-by-general-and-plastic-surgeons
#19
N D Appleton, K D Anderson, K Hancock, M H Scott, C J Walsh
INTRODUCTION Large, complicated ventral hernias are an increasingly common problem. The transversus abdominis muscle release (TAMR) is a recently described modification of posterior components separation for repair of such hernias. We describe our initial experience with TAMR and sublay mesh to facilitate abdominal wall reconstruction. METHODS The study is a retrospective review of patients undergoing TAMR performed synchronously by gastrointestinal and plastic surgeons. RESULTS Twelve consecutive patients had their ventral hernias repaired using the TAMR technique from June 2013 to June 2014...
August 11, 2016: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/27495916/the-abdominal-wall-transplant-as-a-sentinel-skin-graft
#20
James Barnes, Fadi Issa, Georgios Vrakas, Peter Friend, Henk Giele
PURPOSE OF REVIEW: Abdominal wall transplantation is a technique used to achieve abdominal closure after intestinal and multivisceral transplantation. This review focuses on whether there are additional benefits for the skin component as an immune-monitoring tool. RECENT FINDINGS: The largest series of abdominal wall transplants has recently been published. Alongside the physiological advantage gained in abdominal closure, the authors describe the immunological insight that the skin component can provide and how this contributes to the management of patients...
October 2016: Current Opinion in Organ Transplantation
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