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https://www.readbyqxmd.com/read/27923181/combined-oral-contraceptive-use-is-associated-with-both-improvement-and-worsening-of-mood-in-the-different-phases-of-the-treatment-cycle-a-double-blind-placebo-controlled-randomized-trial
#1
Cecilia Lundin, Kristina Gemzell Danielsson, Marie Bixo, Lena Moby, Hanna Bengtsdotter, Izabella Jawad, Lena Marions, Jan Brynhildsen, Agota Malmborg, Ingela Lindh, Inger Sundström Poromaa
OBJECTIVE: Ever since the introduction of combined oral contraception (COC), one of the major reasons for discontinuing the pill use has been mood-related side effects. Moreover, women who discontinue the pill turn to less effective methods whereby the probability of an unintended conception increases. Approximately 4-10% of COC users complain of depressed mood, irritability or increased anxiety, but drug-related causality has been difficult to prove. Given the lack of randomized controlled trials in this area, we aimed to prospectively estimate the severity of adverse mood in COC users that would be as representative of general users as possible...
November 29, 2016: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/27922848/lung-regeneration-steps-toward-clinical-implementation-and-use
#2
Elizabeth A Calle, Katherine L Leiby, MichaSam B Raredon, Laura E Niklason
PURPOSE OF REVIEW: Whole lung tissue engineering is a relatively new area of investigation. In a short time, however, the field has advanced quickly beyond proof of concept studies in rodents and now stands on the cusp of wide-spread scale up to large animal studies. Therefore, this technology is ever closer to being directly clinically relevant. RECENT FINDINGS: The main themes in the literature include refinement of the fundamental components of whole lung engineering and increasing effort to direct induced pluripotent stem cells and lung progenitor cells toward use in lung regeneration...
December 5, 2016: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/27922221/commentary-the-tyranny-of-time-and-the-reality-principle
#3
Russell Gersten
Each of the five articles in this special issue gets "into the weeds" in terms of studying actual classroom or school implementation of evidence-based or promising practices. Virtually all confront the issue of logistics and establishing an infrastructure for ensuring adequate implementation. In general, those studies that ask teachers to change their practice, be it core classwide instruction (Wanzek & Vaughn, this issue) or the whole-class adolescent literacy interventions described in LaRusso et al. (this issue) experienced a good deal more in the way of implementation challenges than those that provided schools with extra services and were able to hire their own personnel to train and oversee as part of an efficacy trial...
December 2016: New Directions for Child and Adolescent Development
https://www.readbyqxmd.com/read/27921861/understanding-intra-vaginal-and-labia-minora-elongation-practices-among-women-heads-of-households-in-zamb%C3%A3-zia-province-mozambique
#4
Carolyn M Audet, Meridith Blevins, Charlotte Buehler Cherry, Lazaro González-Calvo, Ann F Green, Troy D Moon
Intra-vaginal drying and tightening and labia minora elongation are commonly practised in some parts of southern Africa. We sought to capture data on these practices among women living in Zambézia province, Mozambique. Information was gathered from 3543 female heads of household on > 500 variables, including vaginal practices, in 2014. Women who planned to use intra-vaginal tightening substances had 1.84 times higher odds of ever receiving an HIV test (p < 0.001) and 1.40 times higher odds of at least one antenatal care visit attended during last pregnancy (p = 0...
December 6, 2016: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/27920973/consumption-of-caffeinated-energy-drinks-among-youth-and-young-adults-in-canada
#5
Jessica L Reid, Cassondra McCrory, Christine M White, Chantal Martineau, Pat Vanderkooy, Nancy Fenton, David Hammond
The growing market for caffeinated energy drinks (CEDs) has caused concern about excessive caffeine intake and potential adverse effects, particularly among young people. The current study examined patterns of CED consumption among youth and young adults in Canada, using data from a national online survey conducted in October 2014. Data from a non-probability sample of 2040 respondents aged 12-24 from a consumer panel was weighted to national proportions; measures of CED consumption were estimated, including prevalence, excessive daily consumption, and context for use (locations and reasons)...
March 2017: Preventive Medicine Reports
https://www.readbyqxmd.com/read/27920223/correlation-between-pubic-hair-grooming-and-stis-results-from-a-nationally-representative-probability-sample
#6
E Charles Osterberg, Thomas W Gaither, Mohannad A Awad, Matthew D Truesdale, Isabel Allen, Siobhan Sutcliffe, Benjamin N Breyer
OBJECTIVE: STIs are the most common infections among adults. Concurrently, pubic hair grooming is prevalent. Small-scale studies have demonstrated a relationship between pubic hair grooming and STIs. We aim to examine this relationship in a large sample of men and women. DESIGN: We conducted a probability survey of US residents aged 18-65 years. The survey ascertained self-reported pubic hair grooming practices, sexual behaviours and STI history. We defined extreme grooming as removal of all pubic hair more than 11 times per year and high-frequency grooming as daily/weekly trimming...
December 5, 2016: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/27920066/new-concepts-for-an-old-problem-the-diagnosis-of-endometrial-hyperplasia
#7
REVIEW
Peter A Sanderson, Hilary O D Critchley, Alistair R W Williams, Mark J Arends, Philippa T K Saunders
BACKGROUND: Endometrial hyperplasia (EH) is a uterine pathology representing a spectrum of morphological endometrial alterations. It is predominantly characterized by an increase in the endometrial gland-to-stroma ratio when compared to normal proliferative endometrium. The clinical significance of EH lies in the associated risk of progression to endometrioid endometrial cancer (EC) and 'atypical' forms of EH are regarded as premalignant lesions. Traditional histopathological classification systems for EH exhibit wide and varying degrees of diagnostic reproducibility and, as a consequence, standardized patient management can be challenging...
December 4, 2016: Human Reproduction Update
https://www.readbyqxmd.com/read/27919358/risk-factors-for-lack-of-statin-therapy-in-patients-with-diabetes-and-coronary-artery-disease
#8
Huabing Zhang, Jorge Plutzky, Maria Shubina, Alexander Turchin
BACKGROUND: Patients with both diabetes and coronary artery disease (CAD) have exceedingly high cardiovascular risk. Nevertheless, little is known about prevalence of statin therapy in this population and reasons why some patients may not be receiving this potentially life-saving treatment. OBJECTIVE: To investigate prevalence and predictors of statin therapy in patients with combined diabetes and CAD. METHODS: We conducted a retrospective cohort study of primary care patients with diabetes and CAD followed at 2 academic medical centers between 2000 and 2011...
November 2016: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/27919353/dyslipidemia-according-to-gender-and-race-the-brazilian-longitudinal-study-of-adult-health-elsa-brasil
#9
Raul D Santos, Isabela M Bensenor, Alexandre C Pereira, Paulo A Lotufo
BACKGROUND: There is little information regarding lipid profiles of racially mixed populations. Differently from other Latin American countries, the proportion of African ancestry is much higher in Brazil. OBJECTIVE: Verify whether there are differences in the lipid profile between black and white subjects and if people with mixed ancestry have a pattern more closely resembling whites or blacks. METHODS: A total of 15,105 civil servants aged 35-74 years from the ELSA-Brasil study had their fasting lipid profile determined...
November 2016: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/27918940/beyond-flexibility-controlling-stem-cells-in-an-ever-changing-environment
#10
REVIEW
Anne Pfeiffer, Christian Wenzl, Jan U Lohmann
Developmental plasticity is a defining feature of plants allowing them to colonize a wide range of different ecosystems by promoting environmental adaptation. Their postembryonic development requires life-long maintenance of stem cells, which are embedded into specialized tissues, called meristems. The shoot apical meristem gives rise to all above ground tissues and is a complex and dynamic three-dimensional structure harboring cells of different clonal origins and fates. Functionally divergent subdomains are stably maintained despite permanent cell division, however their relative sizes are modified in response to developmental and environmental signals...
December 2, 2016: Current Opinion in Plant Biology
https://www.readbyqxmd.com/read/27918400/a-strategic-approach-for-developing-an-advanced-practice-workforce-from-postgraduate-transition-to-practice-fellowship-programs-and-beyond
#11
Dennis A Taylor, Britney S Broyhill, Allison M Burris, Mary Ann Wilcox
The healthcare provider landscape is rapidly changing. Given the imminent retirement of baby boomer physicians, implementation of the Affordable Care Act, and the increased utilization of health care services by an ever-aging population, the supply of providers cannot keep pace with the demand for services. This has led to an increased utilization of advanced clinical practitioners (ACPs). This article shows how one large highly-matrixed health care system approached identifying this workforce, and how thought leaders worked collaboratively with physicians, administrators, and ACPs to meet a growing demand for providers...
January 2017: Nursing Administration Quarterly
https://www.readbyqxmd.com/read/27918088/cerebrolysin-for-acute-ischaemic-stroke
#12
REVIEW
Liliya Eugenevna Ziganshina, Tatyana Abakumova, Ludivine Vernay
BACKGROUND: Cerebrolysin is a mixture of low-molecular-weight peptides and amino acids derived from pigs' brain tissue, which has potential neuroprotective and neurotrophic properties. It is widely used in the treatment of acute ischaemic stroke in Russia, Eastern Europe, China, and other Asian and post-Soviet countries. OBJECTIVES: To assess the benefits and risks of cerebrolysin for treating acute ischaemic stroke. SEARCH METHODS: In May 2016 we searched the Cochrane Stroke Group Trials Register, CENTRAL, MEDLINE, Embase, Web of Science Core Collection, with Science Citation Index, LILACS, OpenGrey, and a number of Russian Databases...
December 5, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27917781/visualizing-a-natural-antibiotic-nanofactory
#13
T Martin Schmeing
Environmental samples are excellent sources of natural products that possess numerous kinds of therapeutic activities. One important family of natural products is the nonribosomal peptides, which includes penicillin, cyclosporin, viomycin and daptomycin (Cubicin). These peptides are made in bacteria or fungi by large enzymes called nonribosomal peptide synthetases (NRPS). NRPSs are true macromolecular machines or nanofactories, with modular assembly-line logic, a complex catalytic cycle, moving parts and many active sites...
December 1, 2016: Clinical and Investigative Medicine. Médecine Clinique et Experimentale
https://www.readbyqxmd.com/read/27917215/prevalence-of-asthma-among-school-children-in-gaborone-botswana
#14
Andrew Kiboneka, Michael Levin, Thembisile Mosalakatane, Ishmael Makone, Eric Wobudeya, Boikanyo Makubate, Russell Hopp, Loeto Mazhani, Shiang-Ju Kung
BACKGROUND: Asthma prevalence is high (>10%) in developed countries and although data is still missing for most of Africa, rates are increasing in developing regions as they become more westernized. We investigated the prevalence of asthma in school children in Gaborone, Botswana. METHODS: This was a cross sectional descriptive study. ISAAC methodology was used. A representative proportionate size random sample of two age groups of children (13-14 year olds and 6-7 year olds) was consecutively enrolled from 10 schools...
September 2016: African Health Sciences
https://www.readbyqxmd.com/read/27917045/a-biodiversity-hotspot-for-microgastrinae-hymenoptera-braconidae-in-north-america-annotated-species-checklist-for-ottawa-canada
#15
Jose Fernandez-Triana, Caroline Boudreault, Joel Buffam, Ronald Mclean
Microgastrinae wasps (Hymenoptera, Braconidae) from the city of Ottawa and its surroundings (a 50-km radius circle, ~7,800 km(2)) were studied based on 1,928 specimens collected between 1894 and 2010, and housed in the Canadian National Collection of Insects. A total of 158 species from 21 genera were identified, which is by far the highest number of species ever recorded for a locality in North America. An annotated checklist of species is provided. Choeras parasitellae (Bouché, 1834) and Pholetesor nanus (Reinhard, 1880) are recorded for the first time in the Nearctic (previously only known from the Palearctic region), Cotesia depressa (Viereck, 1912) is recorded for the first time in Canada (previously only known from the United States), and Cotesia hemileucae (Riley, 1881) and Protapanteles phlyctaeniae (Muesebeck, 1929) are recorded for the first time in the province of Ontario...
2016: ZooKeys
https://www.readbyqxmd.com/read/27916989/the-toughest-nut-to-crack-will-we-ever-have-a-preventive-and-effective-hiv-1-vaccine
#16
Zwi N Berneman
No abstract text is available yet for this article.
November 2016: Molecular Therapy: the Journal of the American Society of Gene Therapy
https://www.readbyqxmd.com/read/27916703/oogenesis_pred-a-sequence-based-method-for-predicting-oogenesis-proteins-by-six-different-modes-of-chou-s-pseudo-amino-acid-composition
#17
Maryam Rahimi, Mohammad Reza Bakhtiarizadeh, Abdollah Mohammadi-Sangcheshmeh
Regarding to critical roles of oogenesis in formation of ova or unfertilized eggs from the oogonia by mitotic division and subsequent differentiation, the identification of oogenesis-related proteins is of great interest. However, the experimental determination of proteins involved in oogenesis is expensive, time consuming and labor-intensive. Therefore, a new powerful discriminating model is indispensable for classifying oogenesis/non-oogenesis-related proteins with high accuracy and precision. Hereby, for the first time we developed a support vector machine based oogenesis protein prediction method which differentiates oogenesis from non-oogenesis proteins...
December 1, 2016: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/27916330/epidemiology-of-voice-disorders-in-latvian-school-teachers
#18
Baiba Trinite
OBJECTIVES: The prevalence of voice disorders in the teacher population in Latvia has not been studied so far and this is the first epidemiological study whose goal is to investigate the prevalence of voice disorders and their risk factors in this professional group. METHODS: A wide cross-sectional study using stratified sampling methodology was implemented in the general education schools of Latvia. The self-administered voice risk factor questionnaire and the Voice Handicap Index were completed by 522 teachers...
December 1, 2016: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/27916327/does-keeping-adolescent-girls-in-school-protect-against-sexual-violence-quasi-experimental-evidence-from-east-and-southern-africa
#19
Julia Andrea Behrman, Amber Peterman, Tia Palermo
PURPOSE: We examine the relationship between educational attainment in adolescence on young women's lifetime experience of sexual violence in Malawi and Uganda. METHODS: Exposure to Universal Primary Education policies in the mid-1990s serves as a natural experiment to estimate the causal effect of schooling on women's subsequent experience of sexual violence using an instrumented regression discontinuity design and Demographic and Health Survey data. RESULTS: We find a one-year increase in grade attainment leads to a nine-percentage point reduction (p < ...
December 1, 2016: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/27914972/experience-of-primary-care-services-among-early-adolescents-in-england-and-association-with-health-outcomes
#20
Arrash A Yassaee, Dougal S Hargreaves, Kayleigh Chester, Stephanie Lamb, Ann Hagell, Fiona M Brooks
PURPOSE: The aim of this study was to investigate adolescents' (11-15 years) experience of their general practitioner (GP), whether poor reported GP experience was associated with worse physical and mental health measures and whether poor previous GP experience was linked to lower utilization of these services. METHODS: We used logistic regression to analyze data from the 2014 Health Behaviour in School-aged Children study. Four aspects of recent care experience were studied: feeling at ease, feeling treated with respect, satisfaction with doctor's explanation, and feeling able to discuss personal matters...
December 1, 2016: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
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