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https://www.readbyqxmd.com/read/28431065/cha2ds2-vasc-score-and-blood-biomarkers-to-identify-patients-with-atrial-high-rate-episodes-and-paroxysmal-atrial-fibrillation
#1
Paulina Wakula, Benjamin Neumann, Jens Kienemund, Eva Thon-Gutschi, Tatjana Stojakovic, Martin Manninger, Daniel Scherr, Hubert Scharnagl, Martin Kapl, Burkert Pieske, Frank R Heinzel
Aims: Paroxysmal atrial fibrillation (PAF) is often asymptomatic but nonetheless harmful. We evaluated the performance of disease-related blood biomarkers and CHA2DS2-VASc score to discriminate for PAF in patients with continuous rhythm monitoring. Methods and Results: Clinical data and blood samples were obtained from patients with dual-chamber pacemakers selected according to the absence (no_AHRE) or presence of Atrial High-Rate Episodes (AHRE) >6 min in recent device history (case-control approach)...
April 1, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28429854/application-of-3c-insulin-pump-system-in-combination-with-non-invasive-ventilation-in-the-treatment-of-a-patient-with-type-2-diabetes-and-obstructive-sleep-apnea-syndrome
#2
Peng Dong, Jing Xu, Junhong Wang, Chunhong Zhang
We observed the curative effect of 3C insulin system in combination with non-invasive ventilation in a patient with type 2 diabetes and obstructive sleep apnea syndrome (OSAS). 3C insulin pump is a system of devices that closely monitors and effectively regulates blood glucose levels. Non-invasive ventilation has been shown to be an effective treatment for OSAS. A type 2 diabetic patient with concomitant OSAS was treated with a 3C insulin pump system for real-time continuous glucose monitoring and nocturnal non-invasive ventilation for OSAS...
April 21, 2017: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/28427621/engineering-design-and-prototype-development-of-a-full-scale-ultrasound-system-for-virgin-olive-oil-by-means-of-numerical-and-experimental-analysis
#3
Maria Lisa Clodoveo, Vito Moramarco, Antonello Paduano, Raffaele Sacchi, Tiziana Di Palmo, Pasquale Crupi, Filomena Corbo, Vito Pesce, Elia Distaso, Paolo Tamburrano, Riccardo Amirante
The aim of the virgin olive oil extraction process is mainly to obtain the best quality oil from fruits, by only applying mechanical actions while guaranteeing the highest overall efficiency. Currently, the mechanical methods used to extract virgin oils from olives are basically of two types: the discontinuous system (obsolete) and the continuous one. Anyway the system defined as "continuous" is composed of several steps which are not all completely continuous, due to the presence of the malaxer, a device that works in batch...
July 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28426239/performance-of-an-artificial-pancreas-system-for-young-children-with-type-1-diabetes
#4
Mark D DeBoer, Marc D Breton, Christian Wakeman, Elaine M Schertz, Emma G Emory, Jessica L Robic, Laura L Kollar, Boris P Kovatchev, Daniel R Cherñavvsky
BACKGROUND: Young children 5-8 years old with type 1 diabetes (T1D) exhibit clear needs for improved glycemic control but may be limited in their ability to safely interact with an artificial pancreas system. Our goal was to evaluate the safety and performance of an artificial pancreas (AP) system among young children with T1D. RESEARCH DESIGN AND METHODS: In a randomized, crossover trial, children with T1D age 5-8 years were enrolled to receive on separate study periods (in random order) either the UVa AP using the DiAs Control Platform software with child-resistant lock-out screens (followed as an out-patient admission) or their usual insulin pump+continuous glucose monitor (CGM) care at home...
April 20, 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28424755/rapid-low-cost-prototyping-of-transdermal-devices-for-personal-healthcare-monitoring
#5
Sanjiv Sharma, Anwer Saeed, Christopher Johnson, Nikolaj Gadegaard, Anthony Eg Cass
The next generation of devices for personal healthcare monitoring will comprise molecular sensors to monitor analytes of interest in the skin compartment. Transdermal devices based on microneedles offer an excellent opportunity to explore the dynamics of molecular markers in the interstitial fluid, however good acceptability of these next generation devices will require several technical problems associated with current commercially available wearable sensors to be overcome. These particularly include reliability, comfort and cost...
April 2017: Sensing and Bio-Sensing Research
https://www.readbyqxmd.com/read/28410579/assessing-the-usability-by-clinicians-of-vision-a-hierarchical-display-of-patient-collected-physiological-information-to-clinicians
#6
Cubby L Gardner, Fang Liu, Paul Fontelo, Michael C Flanagan, Albert Hoang, Harry B Burke
BACKGROUND: The inability of patients to accurately and completely recount their clinical status between clinic visits reduces the clinician's ability to properly manage their patients. One way to improve this situation is to collect objective patient information while the patients are at home and display the collected multi-day clinical information in parallel on a single screen, highlighting threshold violations for each channel, and allowing the viewer to drill down to any analog signal on the same screen, while maintaining the overall physiological context of the patient...
April 14, 2017: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/28410347/accuracy-of-zero-heat-flux-cutaneous-temperature-in-intensive-care-adults
#7
Claire Dahyot-Fizelier, Solène Lamarche, Thomas Kerforne, Thierry Bénard, Benoit Giraud, Rémy Bellier, Elsa Carise, Denis Frasca, Olivier Mimoz
OBJECTIVES: To compare accuracy of a continuous noninvasive cutaneous temperature using zero-heat-flux method to esophageal temperature and arterial temperature. DESIGN: Prospective study. SETTING: ICU and NeuroICU, University Hospital. PATIENTS: Fifty-two ICU patients over a 4-month period who required continuous temperature monitoring were included in the study, after informed consent. INTERVENTIONS: All patients had esophageal temperature probe and a noninvasive cutaneous device to monitor their core temperature continuously...
April 13, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28406999/dorsal-root-ganglia-neurite-outgrowth-measured-as-a-function-of-changes-in-microelectrode-array-resistance
#8
Jordan M Renna, Jessica M Stukel, Rebecca Kuntz Willits, Erik D Engeberg
Current research in prosthetic device design aims to mimic natural movements using a feedback system that connects to the patient's own nerves to control the device. The first step in using neurons to control motion is to make and maintain contact between neurons and the feedback sensors. Therefore, the goal of this project was to determine if changes in electrode resistance could be detected when a neuron extended a neurite to contact a sensor. Dorsal root ganglia (DRG) were harvested from chick embryos and cultured on a collagen-coated carbon nanotube microelectrode array for two days...
2017: PloS One
https://www.readbyqxmd.com/read/28401454/use-of-flash-glucose-sensing-technology-for-12%C3%A2-months-as-a-replacement-for-blood-glucose-monitoring-in-insulin-treated-type-2-diabetes
#9
Thomas Haak, Hélène Hanaire, Ramzi Ajjan, Norbert Hermanns, Jean-Pierre Riveline, Gerry Rayman
INTRODUCTION: Published evaluations of sensor glucose monitoring use in insulin treated type 2 diabetes are limited. The aim of this study was to assess the impact of flash glucose-sensing technology as a replacement for self-monitoring of blood glucose (SMBG) over a 12-month period in participants with type 2 diabetes who were on intensive insulin therapy. METHODS: An open-label, randomized, controlled study in adults with type 2 diabetes on intensive insulin therapy from 26 European diabetes centers aimed at assessing flash glucose sensing technology was conducted...
April 11, 2017: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/28398267/hand-based-gesture-recognition-for-vehicular-applications-using-ir-uwb-radar
#10
Faheem Khan, Seong Kyu Leem, Sung Ho Cho
Modern cars continue to offer more and more functionalities due to which they need a growing number of commands. As the driver tries to monitor the road and the graphic user interface simultaneously, his/her overall efficiency is reduced. In order to reduce the visual attention necessary for monitoring, a gesture-based user interface is very important. In this paper, gesture recognition for a vehicle through impulse radio ultra-wideband (IR-UWB) radar is discussed. The gestures can be used to control different electronic devices inside a vehicle...
April 11, 2017: Sensors
https://www.readbyqxmd.com/read/28397367/continuous-glucose-monitoring-reveals-hypoglycemia-risk-in-elderly-patients-with-type-2-diabetes-mellitus
#11
Takahiro Ishikawa, Masaya Koshizaka, Yoshiro Maezawa, Minoru Takemoto, Yoshiharu Tokuyama, Toshihiro Saito, Koutaro Yokote
INTRODUCTION: The incidence of type 2 diabetes is higher in elderly patients, in whom this disease is associated with dementia, falling, stroke, and death. We utilized a continuous glucose monitoring (CGM) device to analyze the relationship between hypoglycemia and diabetes treatments to identify risk factors for hypoglycemia (defined as a blood glucose level <70 mg/dL). MATERIALS AND METHODS: We classified 170 patients aged ≥65 years with type 2 diabetes who were receiving steady-state medication (29 of whom were inpatients) into hypoglycemic and non-hypoglycemic groups, and compared their HbA1c levels, treatment types, continuous glucose monitoring data, and other parameters...
April 11, 2017: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/28396294/chronic-ambulatory-electrocorticography-from-human-speech-cortex
#12
Vikram R Rao, Matthew K Leonard, Jonathan K Kleen, Ben A Lucas, Emily A Mirro, Edward F Chang
Direct intracranial recording of human brain activity is an important approach for deciphering neural mechanisms of cognition. Such recordings, usually made in patients with epilepsy undergoing inpatient monitoring for seizure localization, are limited in duration and depend on patients' tolerance for the challenges associated with recovering from brain surgery. Thus, typical intracranial recordings, similar to most non-invasive approaches in humans, provide snapshots of brain activity in acute, highly constrained settings, limiting opportunities to understand long timescale and natural, real-world phenomena...
April 7, 2017: NeuroImage
https://www.readbyqxmd.com/read/28387724/analysis-and-tools-for-improved-management-of-connectionless-and-connection-oriented-ble-devices-coexistence
#13
Antonio Del Campo, Lorenzo Cintioni, Susanna Spinsante, Ennio Gambi
With the introduction of low-power wireless technologies, like Bluetooth Low Energy (BLE), new applications are approaching the home automation, healthcare, fitness, automotive and consumer electronics markets. BLE devices are designed to maximize the battery life, i.e., to run for long time on a single coin-cell battery. In typical application scenarios of home automation and Ambient Assisted Living (AAL), the sensors that monitor relatively unpredictable and rare events should coexist with other sensors that continuously communicate health or environmental parameter measurements...
April 7, 2017: Sensors
https://www.readbyqxmd.com/read/28384272/a-novel-low-complexity-digital-filter-design-for-wearable-ecg-devices
#14
Shadnaz Asgari, Alireza Mehrnia
Wearable and implantable Electrocardiograph (ECG) devices are becoming prevailing tools for continuous real-time personal health monitoring. The ECG signal can be contaminated by various types of noise and artifacts (e.g., powerline interference, baseline wandering) that must be removed or suppressed for accurate ECG signal processing. Limited device size, power consumption and cost are critical issues that need to be carefully considered when designing any portable health monitoring device, including a battery-powered ECG device...
2017: PloS One
https://www.readbyqxmd.com/read/28384179/an-intravaginal-ring-for-real-time-evaluation-of-adherence-to-therapy
#15
John A Moss, Marc M Baum, Jeremiah T Easley, Darren M Cox, Thomas J Smith
Two recent Phase III clinical trials to investigate an intravaginal ring for preventing HIV infection demonstrated that adherence to prescribed device use was a primary driver of efficacy. Surrogate methods for determining adherence in the studies were limited in their inability to monitor temporal patterns of use and allow deconvolution of the effects of adherence and device efficacy on HIV infection rates. To address this issue, we have developed functionality in an intravaginal ring to continuously monitor when the device is being used and maintain a log of adherence that can be accessed by clinicians after it is removed...
2017: PloS One
https://www.readbyqxmd.com/read/28375597/poly-methyl-methacrylate-surface-modification-for-surfactant-free-real-time-toxicity-assay-on-droplet-microfluidic-platform
#16
Raphael Ortiz, Jian Lin Chen, David C Stuckey, Terry W J Steele
Microfluidic droplet reactors have many potential uses, from analytical to synthesis. Stable operation requires preferential wetting of the channel surface by the continuous phase which is often not fulfilled by materials commonly used for lab-on-chip devices. Here we show that a silica nanoparticle (SiNP) layer coated onto a Poly(methyl methacrylate) (PMMA) and other thermoplastics surface enhances its wetting properties by creating nanoroughness, and allows simple grafting of hydrocarbon chains through silane chemistry...
April 7, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28371461/comparison-of-morning-basal-1-bolus-insulin-therapy-insulin-glulisine-insulin-glargine-300-u-ml-vs-insulin-lispro-insulin-glargine-biosimilar-using-continuous-glucose-monitoring-cgm-a-randomized-crossover-study
#17
Soichi Takeishi, Hiroki Tsuboi, Shodo Takegoshi
AIMS/INTRODUCTION: We compared the effects of morning administration of insulin glulisine + insulin glargine 300 U/ml (G+G300) to that of insulin lispro + insulin glargine biosimilar (L+GB). MATERIALS AND METHODS: 30 patients with type 2 diabetes who wear continuous glucose monitoring device in admission after glucose levels were stabilized by morning long-acting and ultra-rapid-acting insulins were randomly allocated to groups who received G+G300 on days 1 and 2 and the same dose L+GB on days 3 and 4, or vice versa...
March 28, 2017: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/28371294/advanced-materials-for-health-monitoring-with-skin-based-wearable-devices
#18
REVIEW
Han Jin, Yasmin Shibli Abu-Raya, Hossam Haick
Skin-based wearable devices have a great potential that could result in a revolutionary approach to health monitoring and diagnosing disease. With continued innovation and intensive attention to the materials and fabrication technologies, development of these healthcare devices is progressively encouraged. This article gives a concise, although admittedly non-exhaustive, didactic review of some of the main concepts and approaches related to recent advances and developments in the scope of skin-based wearable devices (e...
March 29, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28368138/crosscheck-integrating-self-report-behavioral-sensing-and-smartphone-use-to-identify-digital-indicators-of-psychotic-relapse
#19
Dror Ben-Zeev, Rachel Brian, Rui Wang, Weichen Wang, Andrew T Campbell, Min S H Aung, Michael Merrill, Vincent W S Tseng, Tanzeem Choudhury, Marta Hauser, John M Kane, Emily A Scherer
OBJECTIVE: This purpose of this study was to describe and demonstrate CrossCheck, a multimodal data collection system designed to aid in continuous remote monitoring and identification of subjective and objective indicators of psychotic relapse. METHOD: Individuals with schizophrenia-spectrum disorders received a smartphone with the monitoring system installed along with unlimited data plan for 12 months. Participants were instructed to carry the device with them and to complete brief self-reports multiple times a week...
April 3, 2017: Psychiatric Rehabilitation Journal
https://www.readbyqxmd.com/read/28368062/graphene-quantum-dot-based-switch-on-nanosensors-for-intracellular-cytokine-monitoring
#20
Guozhen Liu, Kai Zhang, Ke Ma, Andrew Care, Mark R Hutchinson, Ewa M Goldys
The detection of cytokines in body fluids, cells, tissues and organisms continues to attract considerable attention due to the importance of these key cell signalling molecules in biology and medicine. We report a graphene quantum dot (GQD) based aptasensor able to specifically detect ultra-small amounts of cytokine molecules intracellularly. Graphene quantum dots modified with cytokine aptamers (Ap-GQDs) and epitope modified GQDs (Ep-GQDs) were prepared; both are normally fluorescent at sufficient dilution...
April 3, 2017: Nanoscale
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