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palliative journal

Siu W Lam, Charlotte N Frederiks, Tahar van der Straaten, Aafke H Honkoop, Henk-Jan Guchelaar, Epie Boven
BACKGROUND: The purpose of this study was to evaluate single-nucleotide polymorphisms (SNPs) in genes encoding key metabolising enzymes or involved in pharmacodynamics for possible associations with paclitaxel-induced peripheral neuropathy. METHODS: The study population consists of 188 women from the multicenter, randomised, phase II ATX trial (BOOG2006-06; EudraCT number 2006-006058-83) that received paclitaxel and bevacizumab without or with capecitabine as first-line palliative therapy of HER2-negative metastatic breast cancer...
October 13, 2016: British Journal of Cancer
Harsha Moole, Sirish Dharmapuri, Abhiram Duvvuri, Sowmya Dharmapuri, Raghuveer Boddireddy, Vishnu Moole, Prathyusha Yedama, Naveen Bondalapati, Achuta Uppu, Charan Yerasi
Background. Palliation in advanced unresectable hilar malignancies can be achieved by endoscopic (EBD) or percutaneous transhepatic biliary drainage (PTBD). It is unclear if one approach is superior to the other in this group of patients. Aims. Compare clinical outcomes of EBD versus PTBD. Methods. (i) Study Selection Criterion. Studies using PTBD and EBD for palliation of advanced unresectable hilar malignancies. (ii) Data Collection and Extraction. Articles were searched in Medline, PubMed, and Ovid journals...
2016: Canadian Journal of Gastroenterology & Hepatology
Suzanne Rainsford, Roderick D MacLeod, Nicholas J Glasgow, Donna M Wilson, Christine B Phillips, Robert B Wiles
The 'good death' is one objective of palliative care, with many 'good death' viewpoints and research findings reflecting the urban voice. Rural areas are distinct and need special consideration. This scoping review identified and charted current research knowledge on the 'good' rural death through the perspectives of rural residents, including rural patients with a life-limiting illness, to identify evidence and gaps in the literature for future studies. A comprehensive literature search of English language articles (no date filter applied) was conducted in 2016 (2 January to 14 February) using five library databases...
September 19, 2016: Health & Social Care in the Community
Nikki McCaffrey, Hareth Al-Janabi, David Currow, Renske Hoefman, Julie Ratcliffe
INTRODUCTION: Despite informal caregivers' integral role in supporting people affected by disease or disability, economic evaluations often ignore the costs and benefits experienced by this group, especially in the palliative setting. The purpose of this systematic review is to identify preference-based instruments for measuring care-related outcomes and provide guidance on the selection of instrument in palliative care economic evaluations. METHODS AND ANALYSIS: A comprehensive search of the literature will be conducted from database inception (ASSIA; CINAHL; Cochrane library including DARE, NHS EED, HTA; Econlit; Embase; PsychINFO; PubMed)...
September 12, 2016: BMJ Open
Harsha Moole, Matthew L Bechtold, Micheal Cashman, Fritz H Volmar, Sonu Dhillon, David Forcione, Deepak Taneja, Srinivas R Puli
Self-expandable metal stents (SEMS) are used for palliating inoperable malignant biliary strictures. It is unclear if covered metal stents are superior to uncovered metal stents in these patients. We compared clinical outcomes in patients with covered and uncovered stents. Studies using covered and uncovered metallic stents for palliation in patients with malignant biliary stricture were reviewed. Articles were searched in MEDLINE, PubMed, and Ovid journals. Fixed and random effects models were used to calculate the pooled proportions...
September 2016: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
Fernanda Capella Rugno, Marysia Mara Rodrigues do Prado De Carlo
OBJECTIVE: to identify and evaluate the evidence found in the international scientific literature on the application of the Palliative Outcome Scale (POS) in clinical practice and research in Palliative Care (PC). METHOD: integrative literature review, through the search of publications in journals indexed in PubMed / MEDLINE, LILACS, SciELO and CINAHL databases, between the years 1999 and 2014. RESULTS: the final sample consisted of 11 articles...
2016: Revista Latino-americana de Enfermagem
Melissa Giesbrecht, Valorie A Crooks, Heather Castleden, Nadine Schuurman, Mark W Skinner, Allison M Williams
In 2010, Castleden and colleagues published a paper in this journal using the concept of 'place' as an analytic tool to understand the nature of palliative care provision in a rural region in British Columbia, Canada. This publication was based upon pilot data collected for a larger research project that has since been completed. With the addition of 40 semi-structured interviews with users and providers of palliative care in four other rural communities located across Canada, we revisit Castleden and colleagues' (2010) original framework...
September 2016: Health & Place
Adam James Roberts
In a recent article in this journal, Carl Knight and Andreas Albertsen argue that Rawlsian theories of distributive justice as applied to health and healthcare fail to accommodate both palliative care and the desirability of less painful treatments. The asserted Rawlsian focus on opportunities or capacities, as exemplified in Normal Daniels' developments of John Rawls' theory, results in a normative account of healthcare which is at best only indirectly sensitive to pain and so unable to account for the value of efforts of which the sole purpose is pain reduction...
August 12, 2016: Bioethics
Philippa J Cahill, Elizabeth A Lobb, Christine Sanderson, Jane L Phillips
BACKGROUND: Structured family meeting procedures and guidelines suggest that these forums enhance family-patient-team communication in the palliative care inpatient setting. However, the vulnerability of palliative patients and the resources required to implement family meetings in accordance with recommended guidelines make better understanding about the effectiveness of this type of intervention an important priority. AIM AND DESIGN: This systematic review examines the evidence supporting family meetings as a strategy to address the needs of palliative patients and their families...
August 4, 2016: Palliative Medicine
A S Weintraub, E M Geithner, A Stroustrup, E D Waldman
OBJECTIVE: Compassion fatigue (CF) is distress experienced by caregivers from ongoing contact with patients who are suffering. Burnout (BO) is occupational stress directly related to dissonance between job demands and available resources. Compassion satisfaction (CS) is professional fulfillment experienced through helping others. CF in physicians is not well studied. Neonatologists may be at particular risk for CF by virtue of recurrent exposure to distress in patients and their families...
August 4, 2016: Journal of Perinatology: Official Journal of the California Perinatal Association
Joseph Clark, Clare Gardiner, Amy Barnes
CONTEXT: An increasing amount of health policy is formulated at global level. At this global level, palliative care has attracted support primarily from normative institutions (WHO), not funding agencies. To attract greater global attention from policymakers, it has been argued that an international approach to research is required. However, the extent to which an international approach is being undertaken is unknown. OBJECTIVES: To systematically identify and thematically synthesise all international palliative care research, defined as research involving two or more countries, or focused on the global level...
August 2, 2016: BMJ Supportive & Palliative Care
Chi Eung Danforn Lim, Rachel W C Ng, Nga Chong Lisa Cheng, Maria Cigolini, Cannas Kwok, Frank Brennan
BACKGROUND: End-stage kidney disease (ESKD) is a chronic, debilitative and progressive illness that may need interventions such as dialysis, transplantation, dietary and fluid restrictions. Most patients with ESKD will require renal replacement therapy, such as kidney transplantation or maintenance dialysis. Advance care planning traditionally encompass instructions via living wills, and concern patient preferences about interventions such as cardiopulmonary resuscitation and feeding tubes, or circumstances around assigning surrogate decision makers...
July 26, 2016: Cochrane Database of Systematic Reviews
Nicholas James, Sarah Pirrie, Ann Pope, Darren Barton, Lazaros Andronis, Ilias Goranitis, Stuart Collins, Duncan McLaren, Joe O'Sullivan, Chris Parker, Emilio Porfiri, John Staffurth, Andrew Stanley, James Wylie, Sharon Beesley, Alison Birtle, Janet Brown, Prabir Chakraborti, Martin Russell, Lucinda Billingham
BACKGROUND: Bony metastatic castration-refractory prostate cancer is associated with a poor prognosis and high morbidity. TRAPEZE was a two-by-two factorial randomised controlled trial of zoledronic acid (ZA) and strontium-89 (Sr-89), each combined with docetaxel. All have palliative benefits, are used to control bone symptoms and are used with docetaxel to prolong survival. ZA, approved on the basis of reducing skeletal-related events (SREs), is commonly combined with docetaxel in practice, although evidence of efficacy and cost-effectiveness is lacking...
July 2016: Health Technology Assessment: HTA
Jamie L Penner, Moire Stevenson, Monica P Parmar, Emmanuelle Bélanger
OBJECTIVE: The objective of this article was to explore the extent of the scientific literature and evidence base about the psychosocial needs of students conducting research in the fields of advanced cancer and palliative care. METHOD: A scoping review was conducted in major scientific databases. English-language articles on the topic of interest were retained if they were published in peer-reviewed journals between 1995 and 2013. RESULTS: A total of 3,161 references were screened, and 7 were retained for analysis...
July 15, 2016: Palliative & Supportive Care
Daryll Archibald, Rebecca Patterson, Erna Haraldsdottir, Mark Hazelwood, Shirley Fife, Scott A Murray
INTRODUCTION: Public health palliative care is a term that can be used to encompass a variety of approaches that involve working with communities to improve people's experience of death, dying and bereavement. Recently, public health palliative care approaches have gained recognition and momentum within UK health policy and palliative care services. There is general consensus that public health palliative care approaches can complement and go beyond the scope of formal service models of palliative care...
2016: BMJ Open
Naouma Siouta, K Van Beek, M E van der Eerden, N Preston, J G Hasselaar, S Hughes, E Garralda, C Centeno, A Csikos, M Groot, L Radbruch, S Payne, J Menten
BACKGROUND: Integrated Palliative Care (PC) strategies are often implemented following models, namely standardized designs that provide frameworks for the organization of care for people with a progressive life-threatening illness and/or for their (in)formal caregivers. The aim of this qualitative systematic review is to identify empirically-evaluated models of PC in cancer and chronic disease in Europe. Further, develop a generic framework that will consist of the basis for the design of future models for integrated PC in Europe...
2016: BMC Palliative Care
Maree Azzopardi, Rajesh Thomas, Sanjeevan Muruganandan, David C L Lam, Luke A Garske, Benjamin C H Kwan, Muhammad Redzwan S Rashid Ali, Phan T Nguyen, Elaine Yap, Fiona C Horwood, Alexander J Ritchie, Michael Bint, Claire L Tobin, Ranjan Shrestha, Francesco Piccolo, Christian C De Chaneet, Jenette Creaney, Robert U Newton, Delia Hendrie, Kevin Murray, Catherine A Read, David Feller-Kopman, Nick A Maskell, Y C Gary Lee
INTRODUCTION: Malignant pleural effusions (MPEs) can complicate most cancers, causing dyspnoea and impairing quality of life (QoL). Indwelling pleural catheters (IPCs) are a novel management approach allowing ambulatory fluid drainage and are increasingly used as an alternative to pleurodesis. IPC drainage approaches vary greatly between centres. Some advocate aggressive (usually daily) removal of fluid to provide best symptom control and chance of spontaneous pleurodesis. Daily drainages however demand considerably more resources and may increase risks of complications...
2016: BMJ Open
Grace Meijuan Yang, Shirlyn Hui-Shan Neo, Shawn Zhi Zheng Lim, Lalit Kumar Radha Krishna
BACKGROUND: Although the benefits of palliative care in the outpatient setting are well established, there has been little to support the employing of hospital palliative care services for inpatients with cancer. OBJECTIVE: We conducted a systematic literature review to evaluate the effectiveness of palliative care for cancer patients in the acute inpatient hospital setting. METHODS: Two electronic databases-PubMed and CINAHL Plus-were searched for articles published between 1 January 2005 and 28 May 2015...
June 30, 2016: Journal of Palliative Medicine
Carla Braz Evangelista, Maria Emilia Limeira Lopes, Solange Fatima Geraldo da Costa, Patricia Serpa de Souza Batista, Jaqueline Brito Vidal Batista, Amanda Maritsa de Magalhães Oliveira
OBJECTIVE: to analyze scientifi c articles published in international online journals about palliative care and spirituality. METHODS: an integrative literature review with data collected in September 2014 from the LILACS, SCIELO, MEDLINE/PubMed, and IBECS databases. RESULTS: thirty-nine publications were identifi ed and their textual analysis facilitated through four thematic approaches: the meaning of spirituality in the context of palliative care; palliative care and spiritual support; spirituality and relief of pain and other symptoms in patients under palliative care; and instruments to evaluate the spiritual dimension of the scope of palliative care...
June 2016: Revista Brasileira de Enfermagem
Kun Hyung Kim, Myeong Soo Lee, Tae-Hun Kim, Jung Won Kang, Tae-Young Choi, Jae Dong Lee
BACKGROUND: People living with chronic kidney disease (CKD) experience a range of symptoms and often have complex comorbidities. Many pharmacological interventions for people with CKD have known risks of adverse events. Acupuncture is widely used for symptom management in patients with chronic diseases and in other palliative care settings. However, the safety and efficacy of acupuncture for people with CKD remains largely unknown. OBJECTIVES: We aimed to evaluate the benefits and harms of acupuncture, electro-acupuncture, acupressure, moxibustion and other acupuncture-related interventions (alone or combined with other acupuncture-related interventions) for symptoms of CKD...
2016: Cochrane Database of Systematic Reviews
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